CN102961519A - Compound proplis composition for treating bouine mastitis and preparation method thereof - Google Patents
Compound proplis composition for treating bouine mastitis and preparation method thereof Download PDFInfo
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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Abstract
The invention relates to a compound proplis composition for treating bouine mastitis. The compound proplis composition is prepared from the following components in parts by weight: 15-35 parts of propolis, 15-35 parts of fructus forsythiae, 15-35 parts of hawthorn, 15-35 parts of seaweed, 15-45 parts of myrobalan, 15-35 parts of liquorice, 15-35 parts of oriental wormwood, 15-45 parts of lysimachia christinae hance, 15-35 parts of semen plantaginis and 15-45 parts of juncus bufonius. The compound proplis composition comprises multiple pure traditional Chinese medicine components and has unique advantages which are not owned by the Western medicine; and the compound proplis composition is reasonable in formula, simple in preparation, pollution-free, low in cost and obvious in curative effect and does not have drug residue and toxic or side effect.
Description
Technical field
The present invention relates to compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof, belong to the animal field of medicaments, particularly relate to a kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof.
Background technology
Mammitis of cow is that milch cow is before just before giving birth or the common a kind of multiple diseases of pregnancy duration, the multiple lactation period of being born in breast usefulness milch cow, primary disease is the commonly encountered diseases frequently-occurring disease in the milk cattle cultivating process, sometimes even the life security that jeopardizes female animal and newborn animal thereof, be to cause one of the most serious disease of milch cow economic loss.
Chinese veterinarian thinks that this disease system stops up heat because of female animal three warmers in antenatal puerperal, pyretic toxicity multiple abscess breast and swell swollenly, or the inaccessible milk of mammary gland is accumulated, or polygalactia and the young stock amount of sucking is few, or puerperal, young stock was dead, and milk can not dissipate, accumulate within the breast, pent-up forms primary disease.
Present medicine effect is outstanding not, can produce drug resistance again with the existing drug residue of western medicine, and environment and human health are constituted a serious threat.Therefore researching and developing a kind of specific medicament for the treatment of mammitis of cow is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, drug residue free, have no side effect, effectively treat compound bee-glue composition of mammitis of cow and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of compound bee-glue composition for the treatment of mammitis of cow, by following component by weight mixed preparing form: 15～35 parts of propolis, 15～35 parts of Fructus Forsythiaes, 15～35 parts of Fructus Crataegis, 15～35 parts of Sargassums, 15～45 parts of Fructus Chebulaes, 15～35 parts in Radix Glycyrrhizae, 15～35 parts of Herba Artemisiae Scopariaes, 15～45 parts of Herba Lysimachiaes, 15～35 parts of Semen Plantaginiss, 15～45 parts of Medulla Juncies.
Described various component optimum ratio amount is: 25 parts of propolis, 25 parts of Fructus Forsythiaes, 25 parts of Fructus Crataegis, 25 parts of Sargassums, 30 parts of Fructus Chebulaes, 25 parts in Radix Glycyrrhizae, 25 parts of Herba Artemisiae Scopariaes, 30 parts of Herba Lysimachiaes, 25 parts of Semen Plantaginiss, 30 parts of Medulla Juncies.
A kind of preparation method for the treatment of the compound bee-glue composition of mammitis of cow is to carry out as follows:
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 15～35 parts of propolis, 15～35 parts of Fructus Forsythiaes, 15～35 parts of Fructus Crataegis, 15～35 parts of Sargassums, 15～45 parts of Fructus Chebulaes by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 15～35 parts in Radix Glycyrrhizae, 15～35 parts of Herba Artemisiae Scopariaes, 15～45 parts of Herba Lysimachiaes, 15～35 parts of Semen Plantaginiss, 15～45 parts of Medulla Juncies by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
The medicinal property of each component is as follows:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.
Fructus Forsythiae: bitter, cold, return lung, the heart, small intestine meridian, have the function of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Cure mainly epidemic febrile disease heating, skin ulcer general edema with yellowish skin poison etc.
Fructus Crataegi: sour, sweet, tepor, return stomach, spleen, Liver Channel, have the function of promoting digestion and removing stagnation, circulation of qi promoting dissipating blood stasis; Cure mainly dyspeptic abdominal flatulence, dyspepsia, prolonged lochia etc.
Sargassum: bitter, salty, cold, return liver, stomach, kidney channel, have the function of hard masses softening and resolving, inducing diuresis to remove edema; Cure mainly phlegm retention edema, painful and swollen testis etc.
The Fructus Chebulae: bitter, sour, puckery, flat, return lung, large intestine channel, the function of have astringing intestine to stop diarrhea, astringing the lung; Cure mainly the chronic diarrhea chronic dysentery, have blood in stool, proctoptosis, cough and asthma due to lung deficiency etc.
Radix Glycyrrhizae: sweet, flat, return lung, the heart, spleen channel, have invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, detoxifcation, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning.
Herba Artemisiae Scopariae: bitter, hot, be slightly cold, return spleen, stomach, liver, gallbladder meridian, have the function of eliminating damp-heat, promoting the function of the gallbladder to alleviate jaundice; Cure mainly jaundice, oliguria, eczema pruritus etc.
Herba Lysimachiae: sweet, salty, be slightly cold, return liver, gallbladder, kidney, urinary bladder channel, have the function of clearing away heat-damp and promoting diuresis, diuretic relieving constipation, calculus pain relieving, removing toxic substances and promoting subsidence of swelling; Cure mainly jaundice due to damp-heat, pyretic stranguria, stranguria caused by urinary stone, edema, toxic swelling etc.
Semen Plantaginis: sweet, be slightly cold, return liver, kidney, lung, small intestine meridian, the function that have clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, makes eye bright; Cure mainly the pyretic stranguria hematuria, have loose bowels, conjunctival congestion and swelling pain, edema etc.
Medulla Junci: sweet, light, be slightly cold, GUIXIN, lung, small intestine meridian have the function of clearing away heart-fire, diuresis; Cure mainly difficulty in urination, edema, aphtha of the mouth and tongue etc.
More than all flavor Chinese medicine according to the tcm theory compatible combination, for the various paathogenic factors that cause mammitis of cow, the performance treating both the principal and secondary aspects of a disease effect.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, and it is wide to draw materials, the curative effect highly significant.Select the multi-flavor pure Chinese medicinal preparation, have the not available unique advantage of Western medicine.Theoretical according to the tradition Chinese veterinarian of motherland, optimize this ten herbal medicine, and make them form compound preparation according to best proportioning, clinical practice proves that the treatment mammitis of cow is had specially good effect.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof carries out: (every part by 10g) as follows
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 150 parts of propolis, 150 parts of Fructus Forsythiaes, 150 parts of Fructus Crataegis, 150 parts of Sargassums, 150 parts of Fructus Chebulaes by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 150 parts in Radix Glycyrrhizae, 150 parts of Herba Artemisiae Scopariaes, 150 parts of Herba Lysimachiaes, 150 parts of Semen Plantaginiss, 150 parts of Medulla Juncies by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
Embodiment 2
A kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof carries out: (every part by 10g) as follows
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 250 parts of propolis, 250 parts of Fructus Forsythiaes, 250 parts of Fructus Crataegis, 250 parts of Sargassums, 300 parts of Fructus Chebulaes by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 250 parts in Radix Glycyrrhizae, 250 parts of Herba Artemisiae Scopariaes, 300 parts of Herba Lysimachiaes, 250 parts of Semen Plantaginiss, 300 parts of Medulla Juncies by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
Embodiment 3
A kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof carries out: (every part by 10g) as follows
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 350 parts of propolis, 350 parts of Fructus Forsythiaes, 350 parts of Fructus Crataegis, 350 parts of Sargassums, 450 parts of Fructus Chebulaes by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 350 parts in Radix Glycyrrhizae, 350 parts of Herba Artemisiae Scopariaes, 450 parts of Herba Lysimachiaes, 350 parts of Semen Plantaginiss, 450 parts of Medulla Juncies by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
Clinical trial:
The clinical experiment animal is selected the 380-450 age in days, and Laboratory Diagnosed is the milch cow of mammitis of cow, its isolation is raised separately, and the complete feed of feeding, and be divided at random 3 groups, and 10 every group, 3 groups of feeding environments are identical, and test period is 7 days; The blank group is left intact, and the medicine matched group uses treatment with " YIMUSHENGHUA SAN " by specification; Chinese medicine composition group of the present invention can be got soup with product of the present invention (embodiment of the invention 1 prepared compositions) decocting, waits temperature and gavages ill milch cow, and a day dose is: by every 150g, every day 1 time, be used in conjunction 2-3 days.Chinese medicinal liquor gavages after decocting, the oral rear purpose that reaches the treatment disease by gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 7th day) when following table is the experiment end.
Table is used the situation of traditional Chinese medicine composition for treating mammitis of cow of the present invention clinically:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 10.0 | 60.0 | 30.0 |
| II | The YIMUSHENGHUA SAN group | 0 | 80.0 | 20.0 |
| III | Present composition group | 0 | 90.0 | 10.0 |
This clinical effectiveness statistical analysis, present composition treatment group is being compared difference extremely significantly (P＜0.01) with the YIMUSHENGHUA SAN group aspect the cure rate.
Safety testing:
Choose 10 of 220 age in days healthy cows, 5 times according to the embodiment of the invention 1 made compositions recommended dose gavage 5 days, and during the medication, healthy cow is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of compound bee-glue composition of this treatment mammitis of cow and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound bee-glue composition for the treatment of mammitis of cow, it is characterized in that by following component by weight mixed preparing form: 15～35 parts of propolis, 15～35 parts of Fructus Forsythiaes, 15～35 parts of Fructus Crataegis, 15～35 parts of Sargassums, 15～45 parts of Fructus Chebulaes, 15～35 parts in Radix Glycyrrhizae, 15～35 parts of Herba Artemisiae Scopariaes, 15～45 parts of Herba Lysimachiaes, 15～35 parts of Semen Plantaginiss, 15～45 parts of Medulla Juncies.
2. the compound bee-glue composition for the treatment of mammitis of cow according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 25 parts of Fructus Forsythiaes, 25 parts of Fructus Crataegis, 25 parts of Sargassums, 30 parts of Fructus Chebulaes, 25 parts in Radix Glycyrrhizae, 25 parts of Herba Artemisiae Scopariaes, 30 parts of Herba Lysimachiaes, 25 parts of Semen Plantaginiss, 30 parts of Medulla Juncies.
3. the preparation method of the compound bee-glue composition of a treatment mammitis of cow according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 15～35 parts of propolis, 15～35 parts of Fructus Forsythiaes, 15～35 parts of Fructus Crataegis, 15～35 parts of Sargassums, 15～45 parts of Fructus Chebulaes by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 15～35 parts in Radix Glycyrrhizae, 15～35 parts of Herba Artemisiae Scopariaes, 15～45 parts of Herba Lysimachiaes, 15～35 parts of Semen Plantaginiss, 15～45 parts of Medulla Juncies by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104288508A (en) * | 2014-09-27 | 2015-01-21 | 李保集 | Ointment for mastitis of dairy cows and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20110092509A (en) * | 2010-02-09 | 2011-08-18 | 주식회사 제일바이오 | Composition for treating bovine mastitis |
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