CN104906491A - Pure traditional Chinese medicine composition for treating infectious bursal disease of poultry and preparing methd thereof - Google Patents
Pure traditional Chinese medicine composition for treating infectious bursal disease of poultry and preparing methd thereof Download PDFInfo
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Abstract
The invention relates to a pure traditional Chinese medicine composition for treating the infectious bursal disease of poultry. The pure traditional Chinese medicine composition for treating the infectious bursal disease of poultry is prepared by mixing, by weight, 15-35 parts of fortune eupatorium herbs, 15-55 parts of radix tinosporae, 15-55 parts of wild buckwheats, 15-55 parts of cherokee rose fruits, 15-45 parts of mastic, 15-35 parts of liquorice, 15-35 parts of sarcandra glabra, 15-65 parts of dicliptera chinensis, 15-35 parts of rhizoma cibotii, 15-35 parts of dalbergia wood, 15-65 parts of madder and 15-35 parts of amomum tsao-ko. The pure traditional Chinese medicine composition for treating the infectious bursal disease of poultry has the beneficial effects of being reasonable in component and easy to prepare, has no toxic or side effect, pollution, drug residues or drug resistance, is superfinely smashed, has high bioavailability and a remarkable therapeutic effect and is clinically proven to have special efficacy in treating the infectious bursal disease of poultry.
Description
Technical field
The present invention relates to pure Chinese medicine composition for the treatment of man poultry infectious bursal disease and preparation method thereof, belong to field of animal, be particularly a kind ofly specifically designed to pure Chinese medicine composition for the treatment of man poultry infectious bursal disease and preparation method thereof.
Background technology
Family's poultry infectious bursal disease is that a kind of common transmittable caused by poultry infectious bursal disease virus is sick, main infection 3-6 poultry in age in week, clinically with diarrhoea, row thick white or water sample loose stool for feature, pathological change main manifestations is the congested enlargement of immune organ fabricius bursa or atrophy, and immunity of poultry reduces.This sick mortality rate is very high, very harmful to poultry.
The pathogen of primary disease is poultry infectious bursal disease virus, and this disease spreads all over more or less a hundred country of five continents, is widely distributed.At present, treat this disease the most frequently used be Chinese medicine, but because its prescription is unreasonable or just simply pulverize, particle diameter is excessive, and drug release is comparatively slow, and cause its bioavailability to reduce, clinical effectiveness is not fine; And various antiviral Western medicine is as ribavirin, amantadine etc., the Ministry of Agriculture prohibits the use.
Therefore researching and developing a kind of specific medicament for the treatment of a poultry infectious bursal disease is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, a kind of reasonable recipe is provided, preparation is simple, micronizing, bioavailability are high, successful, to have no drug resistance and pure Chinese medicine composition and preparation method thereof of effective treatment man poultry infectious bursal disease of toxic and side effects.
Implementation of the present invention is as follows for achieving the above object: a kind of pure Chinese medicine composition for the treatment of a poultry infectious bursal disease, by following component by weight mixed preparing form: Herba Eupatorii 15-35 part, Radix Tinosporae 15-55 part, Rhizoma Fagopyri Dibotryis 15-55 part, Fructus Rosae Laevigatae 15-55 part, Olibanum 15-45 part, Radix Glycyrrhizae 15-35 part, Herba Sarcandrae 15-35 part, Herba Diclipterae Chinensis 15-65 part, Rhizoma Cibotii 15-35 part, Lignum Dalbergiae Odoriferae 15-35 part, Radix Rubiae 15-65 part, Fructus Tsaoko 15-35 part.
Described various component optimum ratio amount is: Herba Eupatorii 25 parts, Radix Tinosporae 35 parts, Rhizoma Fagopyri Dibotryis 35 parts, Fructus Rosae Laevigatae 35 parts, Olibanum 30 parts, 25 parts, Radix Glycyrrhizae, Herba Sarcandrae 25 parts, Herba Diclipterae Chinensis 40 parts, Rhizoma Cibotii 25 parts, Lignum Dalbergiae Odoriferae 25 parts, 40 parts, Radix Rubiae, Fructus Tsaoko 25 parts.
Treat a preparation method for the pure Chinese medicine composition of a poultry infectious bursal disease, carry out as follows:
(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;
(2) take Herba Eupatorii 15-35 part, Radix Tinosporae 15-55 part, Rhizoma Fagopyri Dibotryis 15-55 part, Fructus Rosae Laevigatae 15-55 part, Olibanum 15-45 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even;
(3) take Herba Sarcandrae 15-35 part, Herba Diclipterae Chinensis 15-65 part, Rhizoma Cibotii 15-35 part, Lignum Dalbergiae Odoriferae 15-35 part, Radix Rubiae 15-65 part, Fructus Tsaoko 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
The medicinal property of each component is as follows:
Herba Eupatorii: pungent, flat, returns spleen, stomach, lung meridian, has removing dampness by means of aromatics, appetizing of being amusing, delivers the function of expelling summer-heat; Cure mainly Sunstroke, inappetence etc.
Radix Tinosporae: bitter, cold, returns lung, large intestine channel, has the function of heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling, pain relieving; Cure mainly lung-heat cough with asthma, laryngopharynx swelling and pain, dysentery, sore swollen toxin, venom etc.
Rhizoma Fagopyri Dibotryis: micro-pungent, puckery, cool, returns lung meridian, has the function of heat-clearing and toxic substances removing, lung heat clearing evacuation of pus, blood circulation promoting and blood stasis dispelling; Cure mainly laryngopharynx swelling and pain, lung abscess nose pus, acute mastitis, dysentery, carbuncle pyogenic infections from tumour or sore etc.
Radix Glycyrrhizae: sweet, flat, returns lung, the heart, spleen channel, has invigorating the spleen and replenishing QI, expelling phlegm for arresting cough and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function; Cure mainly weakness of the spleen and stomach, cough with asthma, poisoning etc.
Fructus Rosae Laevigatae: sour, sweet, puckery, flat, returns bladder, kidney, large intestine channel, has the function of controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents; Cure mainly spermatorrhea, insufficiency of the spleen chronic diarrhea, chronic dysentery, frequent micturition number, be with inferior.
Olibanum: acrid, bitter, warm, returns liver, the heart, spleen channel, has the function of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, expelling pus and promoting granulation; Cure mainly traumatic injury, qi depression to blood stasis, carbuncle skin infection etc.
Herba Sarcandrae: pungent, bitter, flat, returns liver, heart channel, has clearing away heat and cooling blood, the function of synthetism of stimulating the menstrual flow; Cure mainly heat in blood purpura, traumatic injury, articular rheumatic, fracture swell and ache.
Herba Diclipterae Chinensis: sweet, light, cool, GUIXIN, liver, kidney channel, have the function of heat-clearing and toxic substances removing, removing heat from blood, damp eliminating, diuretic; Cure mainly exogenous high fever, conjunctival congestion and swelling pain, skin ulcer cellulitis pyretic toxicity, epistaxis, hematuria, pyretic stranguria etc.
Rhizoma Cibotii: bitter, sweet, warm, returns kidney, Liver Channel, has the function of invigorating the liver and kidney, strong waist knee joint, wind-damp dispelling; Cure mainly that rheumatic arthralgia, waist are unable, frequent micturition etc. of suffering from a deficiency of the kidney.
Lignum Dalbergiae Odoriferae: pungent, warm, returns liver, spleen channel, has the function of removing stasis to stop bleeding, regulating QI to relieve pain; Cure mainly haematemesis, epistaxis, trauma hemostasis, stagnation of liver-QI costalgia, fall and flutter the pain of injury, vomiting stomachache etc.
Radix Rubiae: bitter, cold, returns Liver Channel, has cooling blood for hemostasis, function that blood stasis dispelling stimulates the menstrual flow; Cure mainly epistaxis, have blood in stool, hematuria, traumatic hemorrhage, traumatic injury, prolonged lochia etc.
Fructus Tsaoko: pungent, warm, returns stomach, spleen channel, has the function of warming middle-JIAO dampness, relieving distension by promoting circulation of QI; Cure mainly Deficiency and coldness of spleen and stomach, food stagnation does not disappear, food etc. is told in regurgitation.
All taste Chinese medicine is according to the theoretical compatible combination of Chinese veterinarian above, for the pathogenic microorganism of family's poultry infectious bursal disease, clinical symptoms and pathological change, plays the effect for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixing is more even; Pure Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and draw materials wide, micronizing, bioavailability are high, curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory, and optimize this 12 taste Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, has specially good effect to treatment man poultry infectious bursal disease.And make poultry product meat reach nuisanceless requirement, meet the export standard of poultry product, effectively ensure that people's is healthy.
Detailed description of the invention
Below in conjunction with preferred embodiment, to according to detailed description of the invention provided by the invention, details are as follows:
Embodiment 1
A kind of pure Chinese medicine composition for the treatment of a poultry infectious bursal disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;
(2) take Herba Eupatorii 150 parts, Radix Tinosporae 150 parts, Rhizoma Fagopyri Dibotryis 150 parts, Fructus Rosae Laevigatae 150 parts, Olibanum 150 parts, 150 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(3) take Herba Sarcandrae 150 parts, Herba Diclipterae Chinensis 150 parts, Rhizoma Cibotii 150 parts, Lignum Dalbergiae Odoriferae 150 parts, 150 parts, Radix Rubiae, Fructus Tsaoko 150 parts by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 2
A kind of pure Chinese medicine composition for the treatment of a poultry infectious bursal disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;
(2) take Herba Eupatorii 250 parts, Radix Tinosporae 350 parts, Rhizoma Fagopyri Dibotryis 350 parts, Fructus Rosae Laevigatae 350 parts, Olibanum 300 parts, 250 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(3) take Herba Sarcandrae 250 parts, Herba Diclipterae Chinensis 400 parts, Rhizoma Cibotii 250 parts, Lignum Dalbergiae Odoriferae 250 parts, 400 parts, Radix Rubiae, Fructus Tsaoko 250 parts by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 3
A kind of pure Chinese medicine composition for the treatment of a poultry infectious bursal disease and preparation method thereof: carry out as follows: (every part by 10g)
(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;
(2) take Herba Eupatorii 350 parts, Radix Tinosporae 550 parts, Rhizoma Fagopyri Dibotryis 550 parts, Fructus Rosae Laevigatae 550 parts, Olibanum 450 parts, 350 parts, Radix Glycyrrhizae by weight, mix 5-10 minute to even;
(3) take Herba Sarcandrae 350 parts, Herba Diclipterae Chinensis 650 parts, Rhizoma Cibotii 350 parts, Lignum Dalbergiae Odoriferae 350 parts, 650 parts, Radix Rubiae, Fructus Tsaoko 350 parts by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Clinical trial:
Clinical experiment animal selects 20 ages in days, body weight at 0.8kg-0.9kg, and Laboratory Diagnosed is the ill broiler of infectious bursal disease.Ill chicken isolation raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 100,3 groups of feeding environments are identical, and experimental period carries out 5 days altogether; Blank group is left intact, and drug control group institute's control drug uses treatment by its description; Chinese medicine composition group of the present invention by product of the present invention (compositions obtained by the embodiment of the present invention 2) the ill poultry of feeding etc., day dose be: feed or the 500kg that drinks water by the present invention's every 100g spice 270kg, every day 2-3 time, be used in conjunction 5; Reached the object of disease therapy by gastrointestinal absorption after oral.Computational methods: mortality rate=dead animal number/experimental animal number × 100%, cure rate=healing number of animals/experimental animal number × 100%, at the end of have symptom rate=have symptom number of animals/experimental animal number × 100%.Following table is the result at the end of experiment.
Efficacy assessment standard:
Cure: spirit is normal, drinking-water of searching for food is normal, and breathe normal, the infectious bursal disease clinical symptom disappearance such as feces is normal, body temperature is normal, test in laboratory has no pathogenic microorganism chicken infectivity bursa of Fabricius virus etc.
At the end of have symptom: clinical symptoms is not improved and is even increased the weight of.
Table is that the situation that the present composition and other medicines treat family's poultry infectious bursal disease contrasts:
| Numbering | Group | Mortality rate % | Cure rate % | At the end of have symptom rate % |
| Ⅰ | Blank group | 21 | 0 | 79 |
| Ⅱ | Fuzheng Jiedu powder group | 10 | 78 | 12 |
| Ⅲ | Chinese medicine composition group of the present invention | 5 | 88 | 7 |
This clinical trial results statistical analysis, present composition group, compared with Fuzheng Jiedu powder group, is wanting in heteropole significantly (P < 0.01) at cure rate.
Safety testing:
Choose the healthy broiler 60 of 20 ages in days, according to the made compositions recommended dose of the embodiment of the present invention 25 times of spices or drinking-water 5 days, during medication, healthy broiler is without any bad or Deviant Behavior performance, drinking-water of searching for food is normal, and it is not remarkable that body weight increase and blank group (i.e. health not administration group) compare difference.
Above-mentioned detailed description of pure Chinese medicine composition of this treatment man poultry infectious bursal disease and preparation method thereof being carried out with reference to embodiment; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (3)
1. treat a pure Chinese medicine composition for a poultry infectious bursal disease, it is characterized in that by following component by weight mixed preparing form: Herba Eupatorii 15-35 part, Radix Tinosporae 15-55 part, Rhizoma Fagopyri Dibotryis 15-55 part, Fructus Rosae Laevigatae 15-55 part, Olibanum 15-45 part, Radix Glycyrrhizae 15-35 part, Herba Sarcandrae 15-35 part, Herba Diclipterae Chinensis 15-65 part, Rhizoma Cibotii 15-35 part, Lignum Dalbergiae Odoriferae 15-35 part, Radix Rubiae 15-65 part, Fructus Tsaoko 15-35 part.
2. the pure Chinese medicine composition for the treatment of man according to claim 1 poultry infectious bursal disease, is characterized in that described various component optimum ratio amount is: Herba Eupatorii 25 parts, Radix Tinosporae 35 parts, Rhizoma Fagopyri Dibotryis 35 parts, Fructus Rosae Laevigatae 35 parts, Olibanum 30 parts, 25 parts, Radix Glycyrrhizae, Herba Sarcandrae 25 parts, Herba Diclipterae Chinensis 40 parts, Rhizoma Cibotii 25 parts, Lignum Dalbergiae Odoriferae 25 parts, 40 parts, Radix Rubiae, Fructus Tsaoko 25 parts.
3. a preparation method for the pure Chinese medicine composition for the treatment of man according to claim 1 and 2 poultry infectious bursal disease, is characterized in that carrying out as follows:
(1) 700 mesh sieves are crossed by after the various compositions in prescription respectively micronizing;
(2) take Herba Eupatorii 15-35 part, Radix Tinosporae 15-55 part, Rhizoma Fagopyri Dibotryis 15-55 part, Fructus Rosae Laevigatae 15-55 part, Olibanum 15-45 part, Radix Glycyrrhizae 15-35 part by weight, mix 5-10 minute to even;
(3) take Herba Sarcandrae 15-35 part, Herba Diclipterae Chinensis 15-65 part, Rhizoma Cibotii 15-35 part, Lignum Dalbergiae Odoriferae 15-35 part, Radix Rubiae 15-65 part, Fructus Tsaoko 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246273A (en) * | 2021-12-31 | 2022-03-29 | 四川农业大学 | Traditional Chinese medicine extract for improving immune function and egg quality of old laying hens |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319288A (en) * | 2011-08-31 | 2012-01-18 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof |
| CN103520674A (en) * | 2013-09-27 | 2014-01-22 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of infectious bursa fabricius disease of poultry |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102319288A (en) * | 2011-08-31 | 2012-01-18 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treating poultry infectious bursal disease and preparation method thereof |
| CN103520674A (en) * | 2013-09-27 | 2014-01-22 | 青岛绿曼生物工程有限公司 | Pure traditional Chinese medicine composition for treatment of infectious bursa fabricius disease of poultry |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246273A (en) * | 2021-12-31 | 2022-03-29 | 四川农业大学 | Traditional Chinese medicine extract for improving immune function and egg quality of old laying hens |
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