CN102961487B - Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination - Google Patents
Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination Download PDFInfo
- Publication number
- CN102961487B CN102961487B CN201210512626.1A CN201210512626A CN102961487B CN 102961487 B CN102961487 B CN 102961487B CN 201210512626 A CN201210512626 A CN 201210512626A CN 102961487 B CN102961487 B CN 102961487B
- Authority
- CN
- China
- Prior art keywords
- parts
- fowlpox
- chinese medicine
- calculus bovis
- venenum bufonis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a compound combination made from pure traditional Chinese medicines and used for treating henpox. The compound combination is prepared by mixing the following components in parts by weight: 15 to 35 parts of houttuynia cordata, 1 to 3 parts of calculus bovis factitious, 1 to 2 parts of venenum bufonis, 15 to 35 parts of borneol, 10 to 30 parts of boswellia carterii, 10 to 30 parts of myrrh, and 15 to 35 parts of rhizoma coptidis. The compound combination has the beneficial effects of being reasonable in composition and simple to prepare, being free from toxic and side effects, pollution, drug residues and tolerance, achieving high biological availability as being subjected to superfine grinding, having a greatly remarkable curative effect, and having a special effect on treating the henpox according to clinical evidence.
Description
Technical field
The present invention relates to the compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox, belong to field of animal, particularly a kind of compound pure Chinese medicine composition and method of making the same being specifically designed to treatment fowlpox.
Background technology
Fowlpox is a kind of high degree in contact sexually transmitted disease caused by fowlpox virus.The chicken of the various length of time and kind all can infect, and it is characterized in that body surface occurs that be dispersed in, tubercular proliferative skin disorders without feather position, also can show as the cellulosic gangrenosum acne hypertrophy focus of upper respiratory tract, oral cavity and esophagus portion mucosa.Primary disease is propagated comparatively slow, and mortality rate, generally between 5%-60%, can affect growth and the egg laying performance of poultry.This disease all can occur throughout the year, and summer and autumn are multiple, is one of principal disease of harm poultry husbandry.
The pathogen of primary disease is fowlpox virus, and virus resistance is to external world very strong.This disease is all poultry countries of throughout world almost, are widely distributed.At present, treat this disease the most frequently used be Chinese medicine and antiviral Western medicine, Chinese medicine is because its prescription is unreasonable or just simply pulverize, and particle diameter is excessive, and drug release is comparatively slow, and cause its bioavailability lower, clinical effectiveness is not fine; And various antiviral drugs such as the Ministry of Agriculture such as ribavirin, amantadine prohibits the use.
Therefore research and develop and a kind ofly treat the drug residue free of fowlpox, the generation that has no drug resistance, the significant specific medicament of clinical effectiveness are one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, a kind of reasonable recipe is provided, preparation is simple, micronizing, bioavailability are high, successful, to have no drug resistance and the compound pure Chinese medicine composition and method of making the same of effective treatment fowlpox of drug residue.
For achieving the above object; implementation of the present invention is as follows: a kind of compound pure Chinese medicine compositions for the treatment of fowlpox, by following component by weight mixed preparing form: Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part, Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part.
Described various component optimum ratio amount is: Herba Houttuyniae 25 parts, artificial Calculus Bovis 2 parts, Venenum Bufonis 1.5 parts, Borneolum Syntheticum 25 parts, Olibanum 20 parts, Myrrha 20 parts, Rhizoma Coptidis 25 parts.
Treat a preparation method for the compound pure Chinese medicine compositions of fowlpox, carry out as follows:
(1) 700 mesh sieves are crossed by after the various compositions (except artificial Calculus Bovis, Venenum Bufonis) in prescription respectively micronizing;
(2) take Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part by weight, mix 5-10 minute to even;
(3) take Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
The medicinal property of each component is as follows:
Herba Houttuyniae: pungent, be slightly cold, returns lung meridian, has the functions such as heat-clearing and toxic substances removing, detumescence and apocenosis, inducing diuresis for treating stranguria syndrome, cure mainly dysentery, intestinal Huang, lung abscess, acute mastitis, stranguria with turbid discharge etc.
Artificial Calculus Bovis: sweet, cool, GUIXIN, Liver Channel, have clear away heart-fire, eliminating phlegm, have one's ideas straightened out, cool liver, endogenous wind stopping, removing toxic substances function; Cure mainly calentura coma, middle wind-phlegm fan, infantile convulsion is twitched, epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle etc.
Venenum Bufonis: sweet, pungent, warm, GUIXIN, stomach warp, have reducing swelling and alleviating pain, dirty, heart tonifying warded off in removing toxic substances, have one's ideas straightened out, the function of refreshment; Cure mainly carbuncle furuncle, laryngopharynx swelling and pain, acute filthy disease stomachache, pyogenic infection, active chronic inflammation, heart failure etc.
Borneolum Syntheticum: pungent, bitter, cold, GUIXIN, spleen, lung meridian, have the function of sensible refreshment, heat-clearing and fire-dispersing, reducing swelling and alleviating pain; Cure mainly coma convulsions, laryngopharynx swelling and pain, heat in the heart tongue boil, cataract, sore swollen toxin etc.
Olibanum: acrid, bitter, warm, GUIXIN, liver, spleen channel, have the function of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, expelling pus and promoting granulation; Cure mainly traumatic injury, too fat to move skin infection, qi depression to blood stasis etc.
Myrrha: pungent, bitter, flat, GUIXIN, liver, spleen channel, have the function of promoting flow of QI and blood, subduing swelling and relieving pain, expelling pus and promoting granulation; Cure mainly too fat to move skin infection, traumatic injury etc.
Rhizoma Coptidis: bitter, cold, returns spleen, stomach, large intestine, gallbladder, heart channel, has the function of heat clearing and damp drying, eliminating fire and detoxication; Cure mainly damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder etc.
All taste Chinese medicine is according to Chinese medical theory compatible combination above, for the pathogenic microorganism of fowlpox and clinical symptoms and pathological change, plays the effect for the treatment of both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixing is more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and draw materials wide, micronizing, bioavailability are high, can also can drink water by spice, curative effect highly significant.The present invention is according to Chinese veterinarian's traditional theory, optimize this seven tastes Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, specially good effect is had to treatment fowlpox, and make its product meat reach nuisanceless requirement, meet the export standard of product, effectively ensure that people's is healthy.
Detailed description of the invention
Below in conjunction with preferred embodiment, to according to detailed description of the invention provided by the invention, details are as follows:
Embodiment 1
A kind of compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox: carry out as follows: (every part by 10g)
(1) 700 mesh sieves are crossed by after the various compositions (except artificial Calculus Bovis, Venenum Bufonis) in prescription respectively micronizing;
(2) take Herba Houttuyniae 150 parts, artificial Calculus Bovis 10 parts, Venenum Bufonis 10 parts, Borneolum Syntheticum 150 parts by weight, mix 5-10 minute to even;
(3) take Olibanum 100 parts, Myrrha 100 parts, Rhizoma Coptidis 150 parts by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 2
A kind of compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox: carry out as follows: (every part by 10g)
(1) 700 mesh sieves are crossed by after the various compositions (except artificial Calculus Bovis, Venenum Bufonis) in prescription respectively micronizing;
(2) take Herba Houttuyniae 250 parts, artificial Calculus Bovis 20 parts, Venenum Bufonis 15 parts, Borneolum Syntheticum 250 parts by weight, mix 5-10 minute to even;
(3) take Olibanum 200 parts, Myrrha 200 parts, Rhizoma Coptidis 250 parts by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Embodiment 3
A kind of compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox: carry out as follows: (every part by 10g)
(1) 700 mesh sieves are crossed by after the various compositions (except artificial Calculus Bovis, Venenum Bufonis) in prescription respectively micronizing;
(2) take Herba Houttuyniae 350 parts, artificial Calculus Bovis 30 parts, Venenum Bufonis 20 parts, Borneolum Syntheticum 350 parts by weight, mix 5-10 minute to even;
(3) take Olibanum 300 parts, Myrrha 300 parts, Rhizoma Coptidis 350 parts by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Clinical trial:
Clinical experiment animal selects 32 ages in days, body weight at 1.5kg-1.6kg, and Laboratory Diagnosed is the ill broiler of fowlpox.Ill chicken isolation raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 60,3 groups of feeding environments are identical, and experimental period carries out 5 days altogether; Blank group is left intact, and drug control group institute's control drug uses treatment by its description; Chinese medicine composition group of the present invention by product of the present invention (compositions obtained by the embodiment of the present invention 1) the ill poultry of feeding etc., day dose be: feed or the 250kg that drinks water by the present invention's every 100g spice 120kg, every day 2-3 time, be used in conjunction 3-5 day; Reached the object of disease therapy by gastrointestinal absorption after oral.Computational methods: mortality rate=dead animal number/experimental animal number × 100%, cure rate=healing number of animals/experimental animal number × 100%.Following table is the result (testing the 5th day) at the end of experiment.
Table is that the Field information situation that the present invention and other medicines treat fowlpox contrasts:
| Numbering | Group | Mortality rate % | Cure rate % | At the end of have symptom rate % |
| I | Blank group | 13.3 | 55.0 | 31.7 |
| II | Fowlpox dissipation group | 8.3 | 80.0 | 11.7 |
| III | Chinese medicine composition group of the present invention | 3.3 | 90.0 | 6.7 |
This clinical effectiveness statistical analysis, present composition treatment group and fowlpox dissipation group in cure rate compared with difference extremely significantly (P < 0.01).
Safety testing:
Choose 20 age in days healthy AA broiler 60, according to the made Chinese medicine composition recommended dose of the embodiment of the present invention 1 10 times of spices or drinking-water 5 days, during medication, healthy chicken is without any bad or Deviant Behavior performance, drinking-water of searching for food is normal, and it is not remarkable that body weight increase and blank group (i.e. health not administration group) compare difference.
Above-mentioned detailed description of carrying out with reference to the compound pure Chinese medicine composition and method of making the same of embodiment to this treatment fowlpox; illustrative instead of determinate; several embodiments can be listed according to institute's limited range; therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (3)
1. treat a compound pure Chinese medicine compositions for fowlpox, it is characterized in that by following component by weight mixed preparing form: Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part, Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part.
2. the compound pure Chinese medicine compositions for the treatment of fowlpox according to claim 1, it is characterized in that by following component by weight mixed preparing form: Herba Houttuyniae 25 parts, artificial Calculus Bovis 2 parts, Venenum Bufonis 1.5 parts, Borneolum Syntheticum 25 parts, Olibanum 20 parts, Myrrha 20 parts, Rhizoma Coptidis 25 parts.
3. a preparation method for the compound pure Chinese medicine compositions for the treatment of fowlpox according to claim 1, is characterized in that carrying out as follows:
(1) 700 mesh sieves are crossed by after the various compositions in prescription except artificial Calculus Bovis, Venenum Bufonis respectively micronizing;
(2) take Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part by weight, mix 5-10 minute to even;
(3) take Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step are obtained, continue mixing 10-15 minute to even.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210512626.1A CN102961487B (en) | 2012-11-22 | 2012-11-22 | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210512626.1A CN102961487B (en) | 2012-11-22 | 2012-11-22 | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102961487A CN102961487A (en) | 2013-03-13 |
| CN102961487B true CN102961487B (en) | 2014-12-31 |
Family
ID=47792106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210512626.1A Expired - Fee Related CN102961487B (en) | 2012-11-22 | 2012-11-22 | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102961487B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497445A (en) * | 2016-02-04 | 2016-04-20 | 史运江 | Traditional Chinese medicine composition for treating henpox |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557368A (en) * | 2004-01-14 | 2004-12-29 | 河北农业大学 | Medicine for preventing and treating fowl pos disease |
| CN101015601A (en) * | 2007-02-13 | 2007-08-15 | 天津生机集团有限公司 | Traditional Chinese powder medicine for treating chicken pox and preparation process thereof |
-
2012
- 2012-11-22 CN CN201210512626.1A patent/CN102961487B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557368A (en) * | 2004-01-14 | 2004-12-29 | 河北农业大学 | Medicine for preventing and treating fowl pos disease |
| CN101015601A (en) * | 2007-02-13 | 2007-08-15 | 天津生机集团有限公司 | Traditional Chinese powder medicine for treating chicken pox and preparation process thereof |
Non-Patent Citations (3)
| Title |
|---|
| 中草药治鸡痘;杨爱起;《农村养殖技术》;20011231(第01期);第17页右栏倒数第1段 * |
| 六应丸治鸡痘;孙巨辉;《中兽医学杂志》;19861231(第01期);第54页右栏倒数第2段至第55页左栏第1段 * |
| 马馨等."方三 黄白乳没散".《中国传统医学宝库 验方经典》.2004, * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102961487A (en) | 2013-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102727770B (en) | Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof | |
| CN103055065B (en) | Pure Chinese medicinal composition for treating enteritis of fish and preparation method of pure Chinese medicinal composition | |
| CN102370971B (en) | Compound bee glue composition for treating fowl pox and preparation method thereof | |
| CN103599362B (en) | Chinese medicine composition for the treatment of swine enzootic pneumonia and preparation method thereof | |
| CN102727848B (en) | Pure traditional Chinese medicine composition used for treating poultry infectious bursal disease, and preparation method thereof | |
| CN102961487B (en) | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination | |
| CN103599220B (en) | Compound bee-glue composition for the treatment of house pet mange and scab and preparation method thereof | |
| CN103585407B (en) | Chinese medicine composition for the treatment of pig infectious atrophic rhinitis and preparation method thereof | |
| CN102961515B (en) | Compound bee-glue composition for the treatment of swine erysipelas and preparation method thereof | |
| CN102670863B (en) | Compound propolis composition for treating acariasis of domestic animal and preparation method thereof | |
| CN102670804B (en) | Compound propolis composition for treating poultry dysentery and preparation method thereof | |
| CN102784371B (en) | Pure traditional medicine composition for treating swine flu and preparation method of pure traditional medicine composition | |
| CN102973668A (en) | Compound pure traditional Chinese medicine composition for treating avian infectious laryngotracheitis and preparation method thereof | |
| CN102935139A (en) | Compound propolis composition for treating chronic gastroenteritis of livestock and preparation method of composition | |
| CN102743508B (en) | Compound propolis composition for treating avian infectious laryngotracheitis and preparation method thereof | |
| CN103479818B (en) | Pure Chinese medicine composition for the treatment of duck pestilence and preparation method thereof | |
| CN103830378B (en) | Chinese veterinary medicine superfine powder for treating chicken caecal coccidiosis and preparation method thereof | |
| CN102973703B (en) | Compound pure Chinese medicine composition for treating enteritis in livestock, and preparation method thereof | |
| CN103550705B (en) | The composition and method of making the same for the treatment of Infectious Tracheobroncheitis | |
| CN103599232B (en) | Pure Chinese medicine composition for the treatment of coccidiosis of domestic fowls and preparation method thereof | |
| CN102727669B (en) | Compound propolis composition used for treating swine erysipelas, and preparation method thereof | |
| CN104906491A (en) | Pure traditional Chinese medicine composition for treating infectious bursal disease of poultry and preparing methd thereof | |
| CN103585606B (en) | Bronchitic Chinese medicine composition for the treatment of chicken infectivity throat and preparation method thereof | |
| CN103585351B (en) | Compound bee-glue composition for the treatment of porcine hyperthermia and preparation method thereof | |
| CN103446540B (en) | Pure Chinese medicine composition for treating chicken reticuloendotheliosis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141231 Termination date: 20151122 |
|
| EXPY | Termination of patent right or utility model |