CN105497445A - Traditional Chinese medicine composition for treating henpox - Google Patents

Traditional Chinese medicine composition for treating henpox Download PDF

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Publication number
CN105497445A
CN105497445A CN201610078862.5A CN201610078862A CN105497445A CN 105497445 A CN105497445 A CN 105497445A CN 201610078862 A CN201610078862 A CN 201610078862A CN 105497445 A CN105497445 A CN 105497445A
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CN
China
Prior art keywords
henpox
chinese medicine
traditional chinese
medicine composition
treating
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Pending
Application number
CN201610078862.5A
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Chinese (zh)
Inventor
史运江
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Individual
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Individual
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Priority to CN201610078862.5A priority Critical patent/CN105497445A/en
Publication of CN105497445A publication Critical patent/CN105497445A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention discloses a traditional Chinese medicine composition for treating henpox, and belongs to the technical field of livestock and poultry medicines. According to causes of henpox, the following traditional Chinese medicines are selected: herb of adder tongue, rhizome of fimbriatestipulate begonia, japanese coniogramme, manyinflorescaned sweetvetch root, tender catchweed bedstraw herb, griffith phymatopsis, chinese pulsatilla root, herb of manyspike chloranthus, Dichocarpum auriculatum (Franch.) W. T. Wang, and common squill bulb; all of the traditional Chinese medicines are decocted with water, and juice is extracted and is used for treating the henpox. Based on controlling experiments, the curative effect of the traditional Chinese medicine composition for treating the henpox is good.

Description

A kind of Chinese medicine composition for the treatment of fowlpox
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition being used for the treatment of fowlpox.
Background technology
Fowlpox is that the one of chicken is acute, contagious disease, and the feature of this disease without on the skin of hair or few hair, varioliform exanthema occurs chicken, or in oral cavity, bottleneck throat mucosa forms cellulosic gangrenosum acne pseudomembrane.The chicken of the various length of time and kind all can infect, and easily causes popular in collective or large-scale chicken farm, weightening finish can be made slow, become thin.When laying hen is infected, egg production temporarily declines, if when concurrent animal infectious diease, parasitic disease and sanitary condition or malnutrition, can cause more death, more easily causes serious loss to children chicken in age.The pathogen of primary disease is fowlpox virus, and virus resistance is to external world very strong.This disease is all poultry countries of throughout world almost, are widely distributed.At present, mainly prevent with fowl pox vaccine.To not injecting fowl pox vaccine, ill chicken main various antiviral drugs such as ribavirin, amantadine etc. are treated, but the Ministry of Agriculture prohibits the use.Therefore research and develop and a kind ofly treat the drug residue free of fowlpox, the generation that has no drug resistance, the significant specific medicament of clinical effectiveness, have great importance.
Summary of the invention
The object of the present invention is to provide a kind of reasonable recipe, preparation is simple, bioavailability is high, successful, to have no drug resistance and the Chinese medicine composition of effective treatment fowlpox of drug residue.
To achieve these goals, the parts by weight of each component of Chinese medicine composition provided by the invention are: Herba Ophioglossi 15-30 part, Rhizoma Begoniae Fimbristipulatae 3-6 part, Coniogramme japonica (Thunb.) Diels 15-30 part, Radix Hedysari 9-30 part, Herba Galii Teneri 6-15 part, Phymatopsis griffithiana (Hook.) J. Sm. 5-15 part, Radix Pulsatillae 9-15 part, Chloranthus multistachys Pei 6-15 part, sow grass 3-10 part, Bulbus scillae scilloidis 3-9 part.
Fang Zhong: Herba Ophioglossi has effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling; Rhizoma Begoniae Fimbristipulatae has effect of clearing away heat and cooling blood, promoting blood circulation and detoxication; Coniogramme japonica (Thunb.) Diels has effect of promoting blood circulation and detoxication, expelling wind and clearing away heat; Radix Hedysari has effect of diuresis detoxification, invigorating QI to consolidate the body surface resistance; Herba Galii Teneri has effect of subduing swelling and detoxicating, clearing away damp-heat, dissipating blood stasis; Phymatopsis griffithiana (Hook.) J. Sm. has effect of heat clearing away, removing heat from blood, removing toxic substances; The Radix Pulsatillae has effect of clearing away heat and cooling blood, removing toxic substances; Chloranthus multistachys Pei have invigorate blood circulation, dissipating blood stasis, dispel the wind removing toxic substances effect; Sow grass has effect of heat-clearing and toxic substances removing, detoxicating and resolving stagnation of pathogens; Bulbus scillae scilloidis has effect of promoting blood circulation and detoxication, reducing swelling and alleviating pain.
The preparation method of Chinese medicine composition of the present invention:
Take each raw medicinal material by weight portion in side, after mixing, add cold water to dipped powder, rear slow fire boiling 30min, filter and discard medicinal residues, obtained water decoction.
Detailed description of the invention
Embodiment one: take Herba Ophioglossi 15g, Rhizoma Begoniae Fimbristipulatae 4g, Coniogramme japonica (Thunb.) Diels 15g, Radix Hedysari 9g, Herba Galii Teneri 6g, Phymatopsis griffithiana (Hook.) J. Sm. 5g, Radix Pulsatillae 9g, Chloranthus multistachys Pei 6g, sow grass 4g, Bulbus scillae scilloidis 4g, after taking the crude drug mixing of described weight portion, add cold water to dipped powder, rear slow fire boiling 30min, filtration discards medicinal residues, obtained water decoction.
Embodiment two: take Herba Ophioglossi 25g, Rhizoma Begoniae Fimbristipulatae 5g, Coniogramme japonica (Thunb.) Diels 25g, Radix Hedysari 20, Herba Galii Teneri 12g, Phymatopsis griffithiana (Hook.) J. Sm. 10g, Radix Pulsatillae 12g, Chloranthus multistachys Pei 12g, sow grass 6g, Bulbus scillae scilloidis 6g, after taking the crude drug mixing of described weight portion, add cold water to dipped powder, rear slow fire boiling 30min, filtration discards medicinal residues, obtained water decoction.
Embodiment three: take Herba Ophioglossi 30g, Rhizoma Begoniae Fimbristipulatae 6g, Coniogramme japonica (Thunb.) Diels 30g, Radix Hedysari 30g, Herba Galii Teneri 15g, Phymatopsis griffithiana (Hook.) J. Sm. 15, Radix Pulsatillae 15g, Chloranthus multistachys Pei 15g, sow grass 9g, Bulbus scillae scilloidis 9g, after taking the crude drug mixing of described weight portion, add cold water to dipped powder, rear slow fire boiling 30min, filtration discards medicinal residues, obtained water decoction.
Clinical trial
Clinical experiment animal selects 32 ages in days, body weight at 1.5kg-1.6kg, and Laboratory Diagnosed is the ill broiler of fowlpox.Ill chicken isolation raised separately, complete feed of feeding, and be divided into 3 groups at random, often organize 60,3 groups of feeding environments are identical, and experimental period carries out 5 days altogether.Blank group is left intact; Western medicine group uses treatment by the description of medicine used; Chinese medicine composition water decoction of the present invention (compositions obtained by the embodiment of the present invention 1) is diluted to 5000ml by Chinese drug-treated group, by 5ml/ (only secondary), 2 times/day, serve on 5d.Computational methods: mortality rate=dead animal number/experimental animal number × 100%, cure rate=healing number of animals/experimental animal number × 100%.Following table is the result (testing the 5th day) at the end of experiment.
Following table is that Chinese drug-treated group and other two groups of therapeutic effect situations contrast:
Numbering Group Mortality rate % Cure rate % At the end of have symptom rate %
1 Blank group 13.3 55.0 31.7
2 Western medicine group 8.3 80.0 11.7
3 Chinese drug-treated group 3.3 90.0 6.7
This clinical effectiveness statistical analysis, traditional Chinese medicine composition for treating group and western medicine group in cure rate compared with difference extremely significantly (P < 0.01).
Safety testing:
Choose 20 age in days healthy AA broiler 60, be divided into administration group and blank group at random, often organize 30.Administration group takes 5 days according to the made Chinese medicine composition decoct of the embodiment of the present invention 1, during medication, healthy chicken is without any bad or Deviant Behavior performance, and drinking-water of searching for food is normal, body weight increases, and to compare difference not remarkable with blank group (i.e. health not administration group).

Claims (1)

1. treat a Chinese medicine composition for fowlpox, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Ophioglossi 15-30 part, Rhizoma Begoniae Fimbristipulatae 3-6 part, Coniogramme japonica (Thunb.) Diels 15-30 part, Radix Hedysari 9-30 part, Herba Galii Teneri 6-15 part, Phymatopsis griffithiana (Hook.) J. Sm. 5-15 part, Radix Pulsatillae 9-15 part, Chloranthus multistachys Pei 6-15 part, sow grass 3-10 part, Bulbus scillae scilloidis 3-9 part.
CN201610078862.5A 2016-02-04 2016-02-04 Traditional Chinese medicine composition for treating henpox Pending CN105497445A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610078862.5A CN105497445A (en) 2016-02-04 2016-02-04 Traditional Chinese medicine composition for treating henpox

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610078862.5A CN105497445A (en) 2016-02-04 2016-02-04 Traditional Chinese medicine composition for treating henpox

Publications (1)

Publication Number Publication Date
CN105497445A true CN105497445A (en) 2016-04-20

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Family Applications (1)

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CN201610078862.5A Pending CN105497445A (en) 2016-02-04 2016-02-04 Traditional Chinese medicine composition for treating henpox

Country Status (1)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961487A (en) * 2012-11-22 2013-03-13 青岛绿曼生物工程有限公司 Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961487A (en) * 2012-11-22 2013-03-13 青岛绿曼生物工程有限公司 Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination

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Application publication date: 20160420

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