CN102961487A - Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination - Google Patents
Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination Download PDFInfo
- Publication number
- CN102961487A CN102961487A CN2012105126261A CN201210512626A CN102961487A CN 102961487 A CN102961487 A CN 102961487A CN 2012105126261 A CN2012105126261 A CN 2012105126261A CN 201210512626 A CN201210512626 A CN 201210512626A CN 102961487 A CN102961487 A CN 102961487A
- Authority
- CN
- China
- Prior art keywords
- parts
- fowlpox
- treatment
- henpox
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention relates to a compound combination made from pure traditional Chinese medicines and used for treating henpox. The compound combination is prepared by mixing the following components in parts by weight: 15 to 35 parts of houttuynia cordata, 1 to 3 parts of calculus bovis factitious, 1 to 2 parts of venenum bufonis, 15 to 35 parts of borneol, 10 to 30 parts of boswellia carterii, 10 to 30 parts of myrrh, and 15 to 35 parts of rhizoma coptidis. The compound combination has the beneficial effects of being reasonable in composition and simple to prepare, being free from toxic and side effects, pollution, drug residues and tolerance, achieving high biological availability as being subjected to superfine grinding, having a greatly remarkable curative effect, and having a special effect on treating the henpox according to clinical evidence.
Description
Technical field
The present invention relates to treat the compound pure Chinese medicine composition and method of making the same of fowlpox, belong to the animal field of medicaments, particularly a kind of compound pure Chinese medicine composition and method of making the same that is specifically designed to the treatment fowlpox.
Background technology
Fowlpox is a kind of height contagious disease that is caused by fowlpox virus.The chicken of the various length of times and kind all can infect, and it is characterized in that proliferative skin disorders that body surface occurs being dispersed in without the feather position, tubercular, also can show as the fiber disposition gangrenosum acne hypertrophy focus of upper respiratory tract, oral cavity and esophagus section mucosa.Primary disease is propagated slower, and mortality rate generally between 5%-60%, can affect growth and the egg laying performance of poultry.This disease all can occur throughout the year, and summer and autumn are multiple, is one of principal disease of harm poultry husbandry.
The pathogen of primary disease is fowlpox virus, and virus resistance to external world is very strong.This disease almost spreads all over all poultry countries of the world, is widely distributed.At present, treat this disease the most frequently used be Chinese medicine and antiviral Western medicine, Chinese medicine is because its prescription is unreasonable or simple pulverizing the just, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And various antiviral drugs such as the Ministry of Agriculture such as ribavirin, amantadine ban use of.
Therefore researching and developing a kind of drug residue free of fowlpox, the generation that has no drug resistance, the significant specific medicament of clinical effectiveness for the treatment of is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability height, successful, have no drug resistance and the compound pure Chinese medicine composition and method of making the same of effective treatment fowlpox of drug residue.
For achieving the above object; implementation of the present invention is as follows: a kind of compound pure Chinese medicine compositions for the treatment of fowlpox, by following component by weight mixed preparing form: Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part, Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part.
Described various component optimum ratio amount is: 25 parts of Herba Houttuyniae, 2 parts of artificial Calculus Boviss, 1.5 parts of Venenum Bufoniss, 25 parts of Borneolum Syntheticums, 20 parts of Olibanums, 20 parts of Myrrhas, 25 parts of Rhizoma Coptidis.
A kind of preparation method for the treatment of the compound pure Chinese medicine compositions of fowlpox, carry out as follows:
(1) the various compositions in the prescription (except artificial Calculus Bovis, the Venenum Bufonis) is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part, mix 5-10 minute to even;
(3) take by weighing by weight Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is as follows:
Herba Houttuyniae: hot, be slightly cold, return lung meridian, have the functions such as heat-clearing and toxic substances removing, detumescence and apocenosis, inducing diuresis for treating stranguria syndrome, cure mainly dysentery, intestinal Huang, lung abscess, acute mastitis, stranguria with turbid discharge etc.
The artificial Calculus Bovis: sweet, cool, GUIXIN, Liver Channel, have clear away heart-fire, eliminating phlegm, have one's ideas straightened out, the function of cool liver, endogenous wind stopping, detoxifcation; Cure mainly that calentura coma, middle wind-phlegm fan, infantile convulsion are twitched, epilepsy is gone mad, laryngopharynx swelling and pain, aphtha of the mouth and tongue, carbuncle furuncle etc.
Venenum Bufonis: sweet, hot, warm, GUIXIN, stomach warp have that reducing swelling and alleviating pain, detoxifcation are warded off dirty, heart tonifying, had one's ideas straightened out, the function of refreshment; Cure mainly carbuncle furuncle, laryngopharynx swelling and pain, acute filthy disease stomachache, pyogenic infection, active chronic inflammation, heart failure etc.
Borneolum Syntheticum: hot, bitter, cold, GUIXIN, spleen, lung meridian have the function of sensible refreshment, heat-clearing and fire-dispersing, reducing swelling and alleviating pain; Cure mainly coma convulsions, laryngopharynx swelling and pain, heat in the heart tongue boil, conjunctival congestion cataracta, sore swollen toxin etc.
Olibanum: hot, bitter, warm, GUIXIN, liver, spleen channel have the function of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, expelling pus and promoting granulation; Cure mainly traumatic injury, too fat to move skin infection, qi depression to blood stasis etc.
Myrrha: hot, bitter, flat, GUIXIN, liver, spleen channel have the function of promoting flow of QI and blood, subduing swelling and relieving pain, expelling pus and promoting granulation; Cure mainly too fat to move skin infection, traumatic injury etc.
Rhizoma Coptidis: bitter, cold, return spleen, stomach, large intestine, gallbladder, heart channel, have the function of heat clearing and damp drying, eliminating fire and detoxication; Cure mainly damp-heat dysentery, hyperactivity of heart-fire, excessiveness of stomach-fire, dampness-heat in the liver and gallbladder etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, for pathogenic microorganism and clinical symptoms and the pathological change of fowlpox, the performance treating both the principal and secondary aspects of a disease effect.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, can also can drink water the curative effect highly significant by spice.The present invention is according to Chinese veterinarian's traditional theory, optimize this seven flavors Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves, the treatment fowlpox there is specially good effect, and make its product meat reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription (except artificial Calculus Bovis, the Venenum Bufonis) is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight 150 parts of Herba Houttuyniae, 10 parts of artificial Calculus Boviss, 10 parts of Venenum Bufoniss, 150 parts of Borneolum Syntheticums, mix 5-10 minute to even;
(3) take by weighing by weight 100 parts of Olibanums, 100 parts of Myrrhas, 150 parts of Rhizoma Coptidis, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription (except artificial Calculus Bovis, the Venenum Bufonis) is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight 250 parts of Herba Houttuyniae, 20 parts of artificial Calculus Boviss, 15 parts of Venenum Bufoniss, 250 parts of Borneolum Syntheticums, mix 5-10 minute to even;
(3) take by weighing by weight 200 parts of Olibanums, 200 parts of Myrrhas, 250 parts of Rhizoma Coptidis, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound pure Chinese medicine composition and method of making the same for the treatment of fowlpox: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription (except artificial Calculus Bovis, the Venenum Bufonis) is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight 350 parts of Herba Houttuyniae, 30 parts of artificial Calculus Boviss, 20 parts of Venenum Bufoniss, 350 parts of Borneolum Syntheticums, mix 5-10 minute to even;
(3) take by weighing by weight 300 parts of Olibanums, 300 parts of Myrrhas, 350 parts of Rhizoma Coptidis, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
The clinical experiment animal selects 32 ages in days, body weight at 1.5kg-1.6kg, and Laboratory Diagnosed is the ill broiler of fowlpox.Ill chicken isolation is raised separately, the complete feed of feeding, and be divided at random 3 groups, and 60 every group, 3 groups of feeding environments are identical, and experimental period was carried out 5 days altogether; The blank group is left intact, and the medicine matched group uses treatment with institute's control drug by its description; Chinese medicine composition group of the present invention is with product of the present invention (embodiment of the invention 1 prepared compositions) the ill poultry of feeding etc., and a day dose is: feed or the 250kg that drinks water by the every 100g spice of the present invention 120kg, every day 2-3 time, be used in conjunction 3-5 day; Reach the purpose for the treatment of disease after oral by gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 5th day) when following table is the experiment end.
Table is the field applicable cases contrast of the present invention and other medicines treatment fowlpox:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 13.3 | 55.0 | 31.7 |
| II | Fowlpox dissipation group | 8.3 | 80.0 | 11.7 |
| III | Chinese medicine composition group of the present invention | 3.3 | 90.0 | 6.7 |
This clinical effectiveness statistical analysis, present composition treatment group is being compared difference extremely significantly (P＜0.01) with fowlpox dissipation group aspect the cure rate.
Safety testing:
Choose 60 of 20 age in days healthy AA broiler, according to 10 times of spices of the embodiment of the invention 1 made Chinese medicine composition recommended dose or drank water 5 days, during the medication, healthy chicken is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and body weight increases that to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of the compound pure Chinese medicine composition and method of making the same of this treatment fowlpox being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound pure Chinese medicine compositions for the treatment of fowlpox, it is characterized in that by following component by weight mixed preparing form: Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part, Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part.
2. the compound bee-glue composition for the treatment of fowlpox according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of Herba Houttuyniae, 2 parts of artificial Calculus Boviss, 1.5 parts of Venenum Bufoniss, 25 parts of Borneolum Syntheticums, 20 parts of Olibanums, 20 parts of Myrrhas, 25 parts of Rhizoma Coptidis.
3. the preparation method of the compound pure Chinese medicine compositions of a treatment fowlpox according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription (except artificial Calculus Bovis, the Venenum Bufonis) is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing by weight Herba Houttuyniae 15-35 part, artificial Calculus Bovis 1-3 part, Venenum Bufonis 1-2 part, Borneolum Syntheticum 15-35 part, mix 5-10 minute to even;
(3) take by weighing by weight Olibanum 10-30 part, Myrrha 10-30 part, Rhizoma Coptidis 15-35 part, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210512626.1A CN102961487B (en) | 2012-11-22 | 2012-11-22 | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210512626.1A CN102961487B (en) | 2012-11-22 | 2012-11-22 | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102961487A true CN102961487A (en) | 2013-03-13 |
| CN102961487B CN102961487B (en) | 2014-12-31 |
Family
ID=47792106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210512626.1A Expired - Fee Related CN102961487B (en) | 2012-11-22 | 2012-11-22 | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102961487B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497445A (en) * | 2016-02-04 | 2016-04-20 | 史运江 | Traditional Chinese medicine composition for treating henpox |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557368A (en) * | 2004-01-14 | 2004-12-29 | 河北农业大学 | Medicine for preventing and treating fowl pos disease |
| CN101015601A (en) * | 2007-02-13 | 2007-08-15 | 天津生机集团有限公司 | Traditional Chinese powder medicine for treating chicken pox and preparation process thereof |
-
2012
- 2012-11-22 CN CN201210512626.1A patent/CN102961487B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1557368A (en) * | 2004-01-14 | 2004-12-29 | 河北农业大学 | Medicine for preventing and treating fowl pos disease |
| CN101015601A (en) * | 2007-02-13 | 2007-08-15 | 天津生机集团有限公司 | Traditional Chinese powder medicine for treating chicken pox and preparation process thereof |
Non-Patent Citations (3)
| Title |
|---|
| 孙巨辉: "六应丸治鸡痘", 《中兽医学杂志》, no. 01, 31 December 1986 (1986-12-31) * |
| 杨爱起: "中草药治鸡痘", 《农村养殖技术》, no. 01, 31 December 2001 (2001-12-31) * |
| 马馨等: "《中国传统医学宝库 验方经典》", 30 September 2004, article ""方三 黄白乳没散"" * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497445A (en) * | 2016-02-04 | 2016-04-20 | 史运江 | Traditional Chinese medicine composition for treating henpox |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102961487B (en) | 2014-12-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102784219B (en) | Compound pure Chinese medicine composition for treating bovine ephemeral fever and preparation method of same | |
| CN102727770B (en) | Pure traditional Chinese medicine composition used for treating swine influenza, and preparation method thereof | |
| CN103055065B (en) | Pure Chinese medicinal composition for treating enteritis of fish and preparation method of pure Chinese medicinal composition | |
| CN102370971A (en) | Compound bee glue composition for treating fowl pox and preparation method thereof | |
| CN103054985B (en) | Pure Chinese medicinal composition for treating red fin disease of eels and preparation method of pure Chinese medicinal composition | |
| CN102727848B (en) | Pure traditional Chinese medicine composition used for treating poultry infectious bursal disease, and preparation method thereof | |
| CN102727693B (en) | Compound propolis composition used for treating swine toxoplasmosis, and preparation method thereof | |
| CN102961487B (en) | Compound combination made from pure traditional Chinese medicines and used for treating henpox and preparation method of combination | |
| CN102961515B (en) | Compound bee-glue composition for the treatment of swine erysipelas and preparation method thereof | |
| CN102670863B (en) | Compound propolis composition for treating acariasis of domestic animal and preparation method thereof | |
| CN102784371B (en) | Pure traditional medicine composition for treating swine flu and preparation method of pure traditional medicine composition | |
| CN102670804B (en) | Compound propolis composition for treating poultry dysentery and preparation method thereof | |
| CN102973668A (en) | Compound pure traditional Chinese medicine composition for treating avian infectious laryngotracheitis and preparation method thereof | |
| CN102935139A (en) | Compound propolis composition for treating chronic gastroenteritis of livestock and preparation method of composition | |
| CN103479818B (en) | Pure Chinese medicine composition for the treatment of duck pestilence and preparation method thereof | |
| CN103550705B (en) | The composition and method of making the same for the treatment of Infectious Tracheobroncheitis | |
| CN102973703B (en) | Compound pure Chinese medicine composition for treating enteritis in livestock, and preparation method thereof | |
| CN102743508B (en) | Compound propolis composition for treating avian infectious laryngotracheitis and preparation method thereof | |
| CN102727669B (en) | Compound propolis composition used for treating swine erysipelas, and preparation method thereof | |
| CN102397529B (en) | Compound propolis composition for treating chicken reticuloendotheliosis and preparation method thereof | |
| CN102397510B (en) | Compound propolis composition for treating chicken Marek's disease and preparation method thereof | |
| CN102397531B (en) | Compound propolis composition for treating duck plague and preparation method thereof | |
| CN104906491A (en) | Pure traditional Chinese medicine composition for treating infectious bursal disease of poultry and preparing methd thereof | |
| CN103585606B (en) | Bronchitic Chinese medicine composition for the treatment of chicken infectivity throat and preparation method thereof | |
| CN103877471A (en) | Traditional Chinese medicinal composition for treating porcine viral diarrhea and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141231 Termination date: 20151122 |
|
| EXPY | Termination of patent right or utility model |