CN104208168B - A kind of for compound traditional Chinese medicine composite treating poultry respiratory infection and preparation method thereof - Google Patents
A kind of for compound traditional Chinese medicine composite treating poultry respiratory infection and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of for compound traditional Chinese medicine composite treating poultry respiratory infection and preparation method thereof, belong to technical field of Chinese medicine for animals.This compound traditional Chinese medicine composite is mainly made up of the crude drug of following parts by weight: Radix Isatidis 20～100 parts, Radix Scutellariae 20～120 parts, the Radix Astragali 15～100 parts, Rhizoma Polygoni Cuspidati 15～100 parts, Radix Glycyrrhizae 5～20 parts, diprophylline 2～10 parts；Preferably, mainly it is made up of the crude drug of following parts by weight: Radix Isatidis 25～75, Radix Scutellariae 30～90 parts, the Radix Astragali 20～60 parts, Rhizoma Polygoni Cuspidati 20～60 parts, Radix Glycyrrhizae 5～15 parts, diprophylline 2～8 parts.Radix Isatidis energy heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving in side, Radix Scutellariae energy heat clearing and damp drying, eliminating fire and detoxication, the Radix Astragali antibacterial, the enhancing human body immunity power of energy, Rhizoma Polygoni Cuspidati energy dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm, Radix Glycyrrhizae energy invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing；Above-mentioned 5 taste Chinese herbal medicine and diprophylline are used in combination the effect that can strengthen prescription therapeutic poultry respiratory infection, and drug effect is rapid, evident in efficacy.
Description
Technical field
Present invention relates particularly to a kind of compound traditional Chinese medicine composite for treating poultry respiratory infection, and this herbal mixture group
The preparation method of compound, belongs to technical field of Chinese medicine for animals.
Background technology
Poultry respiratory tract diseases refers to show obvious respiratory syndrome, such as sneeze, snore, asthma, ataxia, or to exhale
Inhale road symptom to be main disease such as newcastle, influenza, infectious bronchitis, infectious laryngotracheitis, chronic exhale
Inhale tract disease etc..In poultry farming, respiratory tract disease is the most thorny disease, and it is not only difficult to diagnosis and treatment, and susceptible
Degree is high, and almost the poultry of every batch all can fall ill in various degree, and the economic loss caused is huge.
At present, poultry respiratory tract diseases has become the primary disease of harm aquaculture, and many to put prevention first clinically, treatment
It is auxiliary.In recent years, along with antiviral class medicine and the abuse of antibiotics, create substantial amounts of resistant strain, and change
Easily remain in poultry body after learning synthesis class medicament administration, not only affect growth or the production performance of birds, also fowl can be produced
Product eater brings harm.
Summary of the invention
It is an object of the invention to provide a kind of compound traditional Chinese medicine composite for treating poultry respiratory infection.
Meanwhile, the present invention also provides for the preparation method of a kind of compound traditional Chinese medicine composite for treating poultry respiratory infection.
In order to realize object above, the technical solution adopted in the present invention is:
A kind of compound traditional Chinese medicine composite for treating poultry respiratory infection, mainly by the crude drug group of following parts by weight
Become: Radix Isatidis 20～100 parts, Radix Scutellariae 20～120 parts, the Radix Astragali 15～100 parts, Rhizoma Polygoni Cuspidati 15～100 parts, Radix Glycyrrhizae 5～
20 parts, diprophylline 2～10 parts.
Preferably, a kind of compound traditional Chinese medicine composite for treating poultry respiratory infection, mainly former by following parts by weight
Material medicine composition: Radix Isatidis 25～75, Radix Scutellariae 30～90 parts, the Radix Astragali 20～60 parts, Rhizoma Polygoni Cuspidati 20～60 parts, Radix Glycyrrhizae 5～
15 parts, diprophylline 2～8 parts.
It is furthermore preferred that a kind of compound traditional Chinese medicine composite for treating poultry respiratory infection, mainly by following parts by weight
Crude drug forms: Radix Isatidis 25 parts, Radix Scutellariae 30 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 20 parts, 5 parts of Radix Glycyrrhizae, diprophylline
2 parts.
Each crude drug effect is summarized as follows:
Radix Isatidis: for the root of Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort.；Containing indigo, indirubin and several amino acids, such as essence ammonia
Acid, glutamic acid etc., possibly together with various active compositions such as sinigrin, indigo glycosides, couroupitine As；Nature and flavor are bitter, cold, GUIXIN, lung.
Liver, stomach warp；Energy heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving；Cure mainly anemopyretic cold, influenza, epidemic encephalitis, encephalitis b, major part pestilence,
Scarlet fever, individually waits disease；Modern pharmacology proves that Radix Isatidis has antibacterium, antiviral, antiendotoxin, the merit such as anticancer
Effect, has regulation effect simultaneously to immune system.
Radix Scutellariae: for the root of Labiatae Scutellaria plant Radix Scutellariae；Containing flavone compound such as baicalin, neobaicalein, Radix Scutellariae
Glycosides, wogonoside etc., possibly together with various active compositions such as cupreol, campesterol and stigmasterol；Nature and flavor are bitter, cold, return
Lung, the heart, liver, gallbladder, large intestine channel；Can clearing away heat-fire, dampness removing toxic substances, hemostasis, antiabortive；Cure mainly lung-heat cough with asthma, calentura height
The headache of hot coma, liver-fire, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria, tell nosebleed, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.；
Modern pharmacology prove Radix Scutellariae have antimicrobial, antiplatelet aggregation and anticoagulant, antioxidation, anticancer, reduce blood pressure and profit
Urine, blood fat reducing etc. act on.
The Radix Astragali: for pulse family Astragalus Radix Astagali and the root of Radix Astragali；Containing saponin component such as astragaloside, different Huang
Ketone composition such as calycosin, fatty acid such as Palmic acid and linoleic acid, polysaccharide such as astragalus polysaccharides, heteropolysaccharide etc., and
Nearly 20 various trace elements；Radix Astragali nature and flavor are sweet, temperature, return lung, spleen channel；Energy benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema,
Promoting pus discharge and tissue regeneration strengthening；Cure mainly the disease of all Qi and blood deficiencies, such as diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, steal
Antiperspirant, edema, arthralgia due to stagnation of blood, carbuncle difficulty is burst or is burst for a long time and do not holds back；Modern pharmacology proves that the Radix Astragali can affect organism metabolism and have antioxidation
Effect, moreover it is possible to antithrombotic, antiviral, arthritis, anticancer, anti-inflammatory and antalgic, protection cardio-cerebrovascular and promotion hemopoietic
Function.
Rhizoma Polygoni Cuspidati: for rhizome and the root of Polygonaceae arsesmart Rhizoma Polygoni Cuspidati；Containing favourable anthraquinone and anthraquinone glycoside such as rheum emodin, rheum emodin first
The various active compositions such as ether, chrysophanol, anthra-glucoside A, anthra-glucoside B；Nature and flavor are bitter, cold, return liver, gallbladder, lung meridian；Can invigorate blood circulation and dispel
The stasis of blood, dampness removing jaundice eliminating, heat-clearing and toxic substances removing；Cure mainly abdominal mass accumulation, rheumatic arthralgia, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, injury from falling down,
Sore swollen toxin etc.；Modern pharmacology proves that Rhizoma Polygoni Cuspidati has the effect such as antibacterial, antiviral, antitumor, antioxidation, blood fat reducing.
Radix Glycyrrhizae: for pulse family glycyrrhiza genus Radix Glycyrrhizae, smooth bark Radix Glycyrrhizae, the root and rhizome of Glycyrrhiza inflata Bat.；The sweetest containing triterpene saponin
Grass glucin, Glycyrrhiza uralensis Fisch. saponin A, B etc., flavone compound such as 4',7-Dihydroxyflavanone, liquirtin etc., Coumarins chemical combination
Thing such as glycycoumarin, glycyol etc., alkaloids such as quinolines, iloquinoline derivative etc., polysaccharide such as Radix Glycyrrhizae glucosan GBW,
Angelica Polysaccharide UA, UB, UC etc., possibly together with plurality of active ingredients such as Radix Glycyrrhizae benzofuran, n-tricosanes；Radix Glycyrrhizae property
Sweet in the mouth, flat, return spleen, stomach, the heart, lung meridian；Can be with middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription；Process with control weakness of the spleen and stomach,
Asthenia lack of appetite, stomachache loose stool, extremity contraction urgency pain, cardiopalmus, hysteria, consumptive lung disease cough, raw swollen with controlling laryngopharynx swelling and pain, ulcerative carbuncle
Poison, infantile carbuncle and medicine, alimentary toxicosis etc.；Modern pharmacology proves that Radix Glycyrrhizae has antimicrobial, antiinflammatory, antitussive, dispels
The effects such as expectorant, antitumor, mutation, antioxidation, to digestive system, cardiovascular system, reproductive system and brain, renal function
Etc. having regulation effect.
Diprophylline: have direct relexation to airway smooth muscle, has expansion bronchus and effect coronarius, its
Mechanism of action is identical with theophylline；It is considered that by suppression phosphodiesterase, make intracellular cAMP amount improve caused, real
Test think the bronchiectatic activity of theophylline partially due to the result of endogenous epinephrine and norepinephrine release, this
Outward, theophylline is purinoceptor blocker, can resist the contraction to respiratory tract such as adenine；Theophylline can strengthen contraction of diaphragm
Power, especially when contraction of diaphragm is unable, effect is more notable, hence helps to improve respiratory function.
A kind of compound traditional Chinese medicine composite for treating poultry respiratory infection, can use conventional method be prepared as granule,
The common veterinary dosage form such as powder, solution, injection.The present invention only provides the preparation method of a kind of granule, including following
Step: accurately take each taste raw material of Chinese medicine, extracting in water after section according to parts by weight, filtrate is concentrated into precipitate with ethanol after thick paste, then
Reclaim ethanol, be spray-dried dry powder is standby；In dry powder, add diprophylline, be mixed and made into soft material, then pelletize, dry
Do and get final product.
Described extracting in water, for adding 8～10 times amount water, decocts 1～1.5 hour, extracts 2 times.
It is 1.1～1.3 that described filtrate is concentrated into relative density at 70 DEG C.
Described precipitate with ethanol be in thick paste add concentration be 90～95% ethanol make alcohol content reach 47～50%.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Beneficial effects of the present invention:
The present invention uses Radix Isatidis, Radix Scutellariae, the Radix Astragali, Rhizoma Polygoni Cuspidati, Radix Glycyrrhizae, diprophylline totally 6 kinds of crude drug, wherein Baphicacanthus cusia
Root energy heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, for sore throat, scarlet fever, its infusion to bacillus subtilis, staphylococcus aureus,
Sarcine, escherichia coli, Bacillus typhi, paratyphoid fever bacillus, dysentery (will Hayes, Freund) bacillus, bacillus enteritidis
Deng there being inhibitory action；Radix Scutellariae energy heat clearing and damp drying, eliminating fire and detoxication, for hygropyrexia, cough due to lung-heat；Radix Astragali energy enhancing body is exempted from
Epidemic disease function, protects the liver, anti-stress, and has antibacterial action widely, on the one hand can strengthen the phagocytic function of reticuloendothelial system,
Make blood leukocytes and the significant increase of multinuclear leucocyte quantity, make macrophage phagocytic percentage rate and the significant rising of phagocytic index, right
Humoral immunization, cellular immunization all have facilitation, also have the ability of enhanced virus inducement interferon, if easy catching a cold person is in sense
Emit epidemic season and take the Radix Astragali, times of common cold not only can be made to significantly reduce, and cold symptoms can be made relatively light, shorten the course of disease,
On the other hand can also enhancing body anoxia enduring and stress ability；Rhizoma Polygoni Cuspidati energy expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm, be used for
Hygropyrexia, cough with copious phlegm, there is antibacterial, antivirus action, antitussive and antiasthmatic etc. acts on, a kind of flavonoid thing contained in Rhizoma Polygoni Cuspidati
Confrontation staphylococcus aureus, Staphylococcus albus, Bacillus proteus have inhibitory action, and the Rhizoma Polygoni Cuspidati decocting liquid such as 10% is to simple bleb
Exanthema virus, A type capital, influenza Asia section 68-1 virus and angstrom can II type virus (ECHO11) all have inhibitory action；Radix Glycyrrhizae energy
Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, for expelling phlegm for arresting cough, relieving spasm to stop pain, have glucocorticoid sample pharmacological action due to glycyrrhizic acid and
Without serious adverse reaction, clinic is widely used in acute/chronic bronchitis symptom, the additionally glycyrrhizin in Radix Glycyrrhizae or its calcium salt
Having stronger Detoxication, the various preparations of glycyrrhizic acid have antiinflammatory action, and the activity with succinate is higher, and Radix Glycyrrhizae also has
There is phlegm-dispelling functions, throat and bronchial secretion can be promoted, make expectorant easily bring up；Diprophylline is smooth muscle relaxant,
There are expansion bronchus and effect coronarius, energy expansion bronchus smooth muscle, keep tubular breathing smooth and easy, make trachea
Secretions excretes, the above-mentioned natural Chinese medicinal herb of compatibility, and effect is unique.The present invention is by above-mentioned 5 taste pure natural Chinese herbal medicine and two
Brontyl is used in combination the effect that can strengthen prescription therapeutic poultry respiratory infection, and drug effect is rapid, evident in efficacy.
In the prescription of the present invention, Radix Scutellariae cures mainly lung-heat cough with asthma, and the Radix Astragali cures mainly cough due to deficiency of the lung, can improve immunity of organisms, strengthens machine
The immune disease-resistance poison ability of body self, Rhizoma Polygoni Cuspidati has stronger antibacterial ability, Radix Glycyrrhizae have antimicrobial, antiinflammatory, antitussive,
The effect of eliminating the phlegm etc.；The present invention by by above-mentioned pure natural Chinese herbal medicine according to monarch principle reasonable formula, then with two hydroxypropyl tea
Alkali coordinates, and can directly relax airway smooth muscle, expansion bronchus and coronary artery, has poultry respiratory tract diseases stronger
Healing ability.
The present invention uses pure natural Chinese herbal medicine to compound with diprophylline, and crude drug is easy to get, cheap and safety, noresidue,
Without any side effects to poultry body.Above-mentioned compound traditional Chinese medicine composite is prepared as granule by the present invention, and method is simple, easily
Operation, is suitable to large-scale production and popularization and application.
Detailed description of the invention
The present invention is only described in further detail by following embodiment, but does not constitute any limitation of the invention.
Embodiment 1
For treating the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, by the crude drug group of following parts by weight
Become: Radix Isatidis 25 parts, Radix Scutellariae 30 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 20 parts, 5 parts of Radix Glycyrrhizae, diprophylline 2 parts.
For treating the preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, comprise the following steps:
Each taste raw material of Chinese medicine is accurately taken according to parts by weight, section, extracting in water 2 times, add 10 times amount water for the first time, decoct 1.5
Hour, second time adds 8 times amount water, decocts 1 hour, collecting decoction, filters, and filtrate is concentrated into relative density at 70 DEG C and is
1.1 obtain thick paste, and adding ethanol to the alcohol content that concentration is 95% in thick paste is 50%, stands, filters, and filtrate reclaims second
Be spray-dried after alcohol dry powder is standby；In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then make
Grain, drying.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Embodiment 2
For treating the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, by the crude drug group of following parts by weight
Become: Radix Isatidis 50 parts, Radix Scutellariae 60 parts, the Radix Astragali 40 parts, Rhizoma Polygoni Cuspidati 40 parts, 10 parts of Radix Glycyrrhizae, diprophylline 3 parts.
For treating the preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, comprise the following steps:
Each taste raw material of Chinese medicine is accurately taken according to parts by weight, section, extracting in water 2 times, add 8 times amount water for the first time, decoct 1 little
Time, second time adds 8 times amount water, decocts 1 hour, collecting decoction, filters, and filtrate is concentrated into relative density at 70 DEG C and is
1.3 obtain thick paste, and adding ethanol to the alcohol content that concentration is 90% in thick paste is 47%, stands, filters, and filtrate reclaims second
Be spray-dried after alcohol dry powder is standby；In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then make
Grain, drying.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Embodiment 3
For treating the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, by the crude drug group of following parts by weight
Become: Radix Isatidis 35 parts, Radix Scutellariae 90 parts, the Radix Astragali 25 parts, Rhizoma Polygoni Cuspidati 60 parts, 8 parts of Radix Glycyrrhizae, diprophylline 2 parts.
For treating the preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, comprise the following steps:
Each taste raw material of Chinese medicine is accurately taken according to parts by weight, section, extracting in water 2 times, add 10 times amount water for the first time, decoct 1
Hour, second time adds 8 times amount water, decocts 1 hour, collecting decoction, filters, and filtrate is concentrated into relative density at 70 DEG C and is
1.2 obtain thick paste, and adding ethanol to the alcohol content that concentration is 90% in thick paste is 47.5%, stands, filters, and filtrate reclaims second
Be spray-dried after alcohol dry powder is standby；In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then make
Grain, drying.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Embodiment 4
For treating the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, by the crude drug group of following parts by weight
Become: Radix Isatidis 75 parts, Radix Scutellariae 50 parts, the Radix Astragali 60 parts, Rhizoma Polygoni Cuspidati 30 parts, 15 parts of Radix Glycyrrhizae, diprophylline 8 parts.
For treating the preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, comprise the following steps:
Each taste raw material of Chinese medicine is accurately taken according to parts by weight, section, extracting in water 2 times, add 10 times amount water for the first time, decoct 1.5
Hour, second time adds 8 times amount water, decocts 1.5 hours, collecting decoction, filters, and filtrate is concentrated into relative density at 70 DEG C
Be 1.2 thick paste, in thick paste add concentration be 95% ethanol to alcohol content be 50%, stand, filter, filtrate reclaim
Be spray-dried after ethanol dry powder is standby；In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then
Granulation, drying.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Embodiment 5
For treating the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, by the crude drug group of following parts by weight
Become: Radix Isatidis 25 parts, Radix Scutellariae 120 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 100 parts, 5 parts of Radix Glycyrrhizae, diprophylline 10 parts.
For treating the preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, comprise the following steps:
Each taste raw material of Chinese medicine is accurately taken according to parts by weight, section, extracting in water 2 times, add 10 times amount water for the first time, decoct 1.5
Hour, second time adds 8 times amount water, decocts 1.5 hours, collecting decoction, filters, and filtrate is concentrated into relative density at 70 DEG C
Be 1.2 thick paste, in thick paste add concentration be 95% ethanol to alcohol content be 50%, stand, filter, filtrate reclaim
Be spray-dried after ethanol dry powder is standby；In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then
Granulation, drying.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Embodiment 6
For treating the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, by the crude drug group of following parts by weight
Become: Radix Isatidis 100 parts, Radix Scutellariae 30 parts, the Radix Astragali 100 parts, Rhizoma Polygoni Cuspidati 20 parts, 20 parts of Radix Glycyrrhizae, diprophylline 2 parts.
For treating the preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, comprise the following steps:
Each taste raw material of Chinese medicine is accurately taken according to parts by weight, section, extracting in water 2 times, add 10 times amount water for the first time, decoct 1
Hour, second time adds 8 times amount water, decocts 1 hour, collecting decoction, filters, and filtrate is concentrated into relative density at 70 DEG C and is
1.2 obtain thick paste, and adding ethanol to the alcohol content that concentration is 95% in thick paste is 47.5%, stands, filters, and filtrate reclaims second
Be spray-dried after alcohol dry powder is standby；In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then make
Grain, drying.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1～2g of every lkg body weight, once-a-day,
It within 3rd, it is a course for the treatment of.
Test example
Experimental animal: according to epidemiology, clinical symptoms, pathology cuts open inspection, identification and isolation of pathogen comprehensive diagnos is bronchus
Scorching sick chicken, randomly selects 560, is divided into 8 groups, often group 70, and test group 1～6 uses embodiment 1～6 successively
The granule of preparation is treated, and matched group uses commercially available exhaling to breathe heavily peaceful (moistening bio tech ltd purchased from Guangdong), and
Blank group does not use any medicine, is used in conjunction 3 days, observes curative effect and adds up healing, effective and invalid number, calculating and cure
Rate, result of the test refers to table 1 below.
Curative effect judging standard:
Cure: mental status is good, does not has chronic respiratory diseases, ataxia situation, and bronchus does not has secretions；
Effective: disease is clearly better；
Invalid: mental status is poor, there is sleeping ground not rise, have social phenomenon, have chronic respiratory diseases ataxia phenomenon.
The therapeutic effect that chicken respiratory is infected by table 1 each process group
Conclusion: as it can be seen from table 1 the cure rate that test group 1～6 is when treating chicken respiratory and infecting reaches more than 95%,
And matched group is only 61%.Statistical analysis shows, the cure rate of test group is significantly higher than matched group (P ＜ 0.01).Test knot
Fruit shows, chicken respiratory is infected and has good therapeutic efficiency by the granule of the embodiment of the present invention 1～6 preparation.
Claims (7)
1. the compound traditional Chinese medicine composite being used for treating poultry respiratory infection, it is characterized in that: be made up of the crude drug of following parts by weight: Radix Isatidis 20～100 parts, Radix Scutellariae 20～120 parts, the Radix Astragali 15～100 parts, Rhizoma Polygoni Cuspidati 15～100 parts, Radix Glycyrrhizae 5～20 parts, diprophylline 2～10 parts.
Compound traditional Chinese medicine composite for treating poultry respiratory infection the most according to claim 1, it is characterised in that: it is made up of the crude drug of following parts by weight: Radix Isatidis 25～75, Radix Scutellariae 30～90 parts, the Radix Astragali 20～60 parts, Rhizoma Polygoni Cuspidati 20～60 parts, Radix Glycyrrhizae 5～15 parts, diprophylline 2～8 parts.
Compound traditional Chinese medicine composite for treating poultry respiratory infection the most according to claim 2, it is characterised in that: it is made up of the crude drug of following parts by weight: Radix Isatidis 25 parts, Radix Scutellariae 30 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 20 parts, 5 parts of Radix Glycyrrhizae, diprophylline 2 parts.
4. the preparation method of the compound traditional Chinese medicine composite for treating poultry respiratory infection as described in any one of claim 1-3, it is characterized in that: comprise the following steps: accurately take each taste raw material of Chinese medicine according to parts by weight, extracting in water after section, filtrate is concentrated into precipitate with ethanol after thick paste, recycling ethanol, be spray-dried dry powder is standby；In dry powder, add diprophylline, be mixed and made into soft material, then pelletize, drying.
The preparation method of the compound traditional Chinese medicine composite for treating poultry respiratory infection the most according to claim 4, it is characterised in that: described extracting in water, for adding 8～10 times amount water, decocts 1～1.5 hour, extracts 2 times.
The preparation method of the compound traditional Chinese medicine composite for treating poultry respiratory infection the most according to claim 4, it is characterised in that: it is 1.1～1.3 that described filtrate is concentrated into relative density at 70 DEG C.
The preparation method of the compound traditional Chinese medicine composite for treating poultry respiratory infection the most according to claim 4, it is characterised in that: described precipitate with ethanol be in thick paste add concentration be 90～95% ethanol make alcohol content reach 47～50%.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085048A (en) * | 2006-06-06 | 2007-12-12 | 河南农业大学 | Traditional Chinese medicine for detoxicating for animals and preparation method thereof |
| CN102475835A (en) * | 2010-11-25 | 2012-05-30 | 北京东方运嘉医药科技开发有限公司 | Pharmaceutical composition for treating common cold or cough caused by common cold in children and preparation method thereof |
| CN102247514A (en) * | 2011-06-29 | 2011-11-23 | 北京康华远景科技有限公司 | Traditional Chinese medicine composite for treating Newcastle disease |
| CN102872307A (en) * | 2012-09-29 | 2013-01-16 | 李继红 | Traditional Chinese medicine oral liquid for preventing and treating virus diseases of poultry and method for preparing traditional Chinese medicine oral liquid |
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Address after: 451162 Zhengzhou economic comprehensive experimentation area, Zhengzhou air port, Henan, Xingang Province Patentee after: Henan Hou Yi Industry Group Co., Ltd. Address before: 451162 Xingang, Henan, Zhengzhou, Hong Kong airport on the eastern side of the road on the eastern side of Zhengzhou Patentee before: Zhengzhou Houyi Pharmaceutical Co., Ltd. |