CN104208168A - Compound traditional Chinese medicine composition for treating poultry respiratory tract infection and preparation method thereof - Google Patents
Compound traditional Chinese medicine composition for treating poultry respiratory tract infection and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a compound traditional Chinese medicine composition for treating poultry respiratory tract infection and a preparation method thereof, and belongs to the technical field of veterinary traditional Chinese medicine. The compound traditional Chinese medicine composition is mainly composed of the following traditional Chinese herbals in parts by weight: 20 to 100 parts of isatis root, 20 to 120 parts of radix scutellariae, 15 to 100 parts of radix astragali, 15 to 100 parts of polygonum cuspidatum, 5 to 20 parts of licorice, and 2 to 10 parts of dihydroxypropyl theophylline; and preferably is mainly composed of the following traditional Chinese herbals in parts by weight: 25 to 75 parts of isatis root, 30 to 90 parts of radix scutellariae, 20 to 60 parts of radix astragali, 20 to 60 parts of polygonum cuspidatum, 5 to 15 parts of licorice, and 2 to 8 parts of dihydroxypropyl theophylline. In the formula, the isatis root has the functions of clearing heat, removing toxicity, cooling blood, and soothing the throat, the radix scutellariae has the functions of clearing heat, drying dampness, purging fire, and removing toxicity, the radix astragali has the functions of preventing bacteria and strengthening the organism immunity, the polygonum cuspidatum has the functions of dissolving blood stasis, relieving pains, stopping coughing, and reducing phlegm, and the licorice has the functions of tonifying the spleen, boosting qi, clearing heat, and removing toxicity. The five traditional Chinese herbals are co-used with dihydroxypropyl theophylline to enhance the effect of the formula on treating poultry respiratory tract infection, and the compound traditional Chinese medicine composition has the advantages of quick effect and prominent curative effect.
Description
Technical field
The present invention is specifically related to a kind of compound traditional Chinese medicine composite being used for the treatment of poultry respiratory infection, and the preparation method of this compound traditional Chinese medicine composite, belongs to technical field of Chinese medicine for animals.
Background technology
Poultry respiratory tract diseases refers to the obvious respiratory syndrome of performance, as sneeze, snore, asthma, ataxia, or the disease based on respiratory symptom is as newcastle, influenza, infectious bronchitis, infectious laryngotracheitis, chronic respiratory tract disease etc.In poultry farming, respiratory tract disease is disease the most thorny, and it is not only difficult to diagnosis and treatment, and susceptible degree is high, and almost the poultry of every batch all can fall ill in various degree, and the economic loss caused is huge.
At present, poultry respiratory tract diseases has become the primary disease of harm aquaculture, and clinically mainly with An ounce of prevention is worth a pound of cure.In recent years, along with the abuse of antiviral class medicine and antibiotics, create a large amount of resistant strains, and easily residual in poultry body after chemosynthesis class medicament administration, not only affect growth or the fertility performance of birds, also can bring harm to poultry product eater.
Summary of the invention
The object of this invention is to provide a kind of compound traditional Chinese medicine composite being used for the treatment of poultry respiratory infection.
Meanwhile, the present invention also provides a kind of preparation method being used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection.
In order to realize above object, the technical solution adopted in the present invention is:
A kind of compound traditional Chinese medicine composite being used for the treatment of poultry respiratory infection, crude drug primarily of following parts by weight forms: Radix Isatidis 20 ~ 100 parts, Radix Scutellariae 20 ~ 120 parts, the Radix Astragali 15 ~ 100 parts, Rhizoma Polygoni Cuspidati 15 ~ 100 parts, 5 ~ 20 parts, Radix Glycyrrhizae, diprophylline 2 ~ 10 parts.
Preferably, be used for the treatment of a compound traditional Chinese medicine composite for poultry respiratory infection, the crude drug primarily of following parts by weight forms: Radix Isatidis 25 ~ 75, Radix Scutellariae 30 ~ 90 parts, the Radix Astragali 20 ~ 60 parts, Rhizoma Polygoni Cuspidati 20 ~ 60 parts, 5 ~ 15 parts, Radix Glycyrrhizae, diprophylline 2 ~ 8 parts.
Preferred, a kind of compound traditional Chinese medicine composite being used for the treatment of poultry respiratory infection, the crude drug primarily of following parts by weight forms: Radix Isatidis 25 parts, Radix Scutellariae 30 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 20 parts, 5 parts, Radix Glycyrrhizae, diprophylline 2 parts.
Each crude drug effect is summarized as follows:
Radix Isatidis: be the root of Cruciferae Isatis indigotica Fort. platymiscium Isatis indigotica Fort.; Containing indigo, indirubin and several amino acids, as arginine, glutamic acid etc., also containing various active compositions such as sinigrin, indigo glycosides, couroupitine As; Nature and flavor are bitter, cold, GUIXIN, lung.Liver, stomach warp; Energy heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving; Cure mainly anemopyretic cold, influenza, epidemic encephalitis, encephalitis b, major part pestilence, scarlet fever, wait disease separately; Modern pharmacology proves that Radix Isatidis has antibacterium, antiviral, antiendotoxin, the effect such as anticancer, has regulating action to immune system simultaneously.
Radix Scutellariae: be the root of Labiatae Scutellaria plant Radix Scutellariae; Containing flavone compound as baicalin, neobaicalein, baicalin, wogonoside etc., also containing various active compositions such as cupreol, campesterol and stigmasterol; Nature and flavor are bitter, cold, return lung, the heart, liver, gallbladder, large intestine channel; Can clearing away heat-fire, dampness removing toxic substances, hemostasis, antiabortive; Cure mainly lung-heat cough with asthma, calentura unconsciousness due to high fever, liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria, tell nosebleed, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.; Modern pharmacology prove Radix Scutellariae have antimicrobial, antiplatelet aggregation and anticoagulant, antioxidation, anticancer, reduce blood pressure and the effect such as diuresis, blood fat reducing.
The Radix Astragali: be the root of pulse family Astragalus Radix Astagali and Radix Astragali; Containing saponin component as astragaloside, isoflavones components is as calycosin, and fatty acid is as Palmic acid and linoleic acid, and polysaccharide is as astragalus polysaccharides, heteropolysaccharide etc., and nearly 20 various trace elements; Radix Astragali nature and flavor are sweet, and temperature, returns lung, spleen channel; Energy benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening; Cure mainly the disease of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle difficulty is burst or is burst for a long time and do not hold back; Modern pharmacology proves that the Radix Astragali can affect organism metabolism and have antioxidation, can also antithrombotic, antiviral, arthritis, anticancer, anti-inflammatory and antalgic, protection cardio-cerebrovascular and promotion hemopoietic function.
Rhizoma Polygoni Cuspidati: be rhizome and the root of Polygonaceae arsesmart Rhizoma Polygoni Cuspidati; Containing favourable anthraquinone and anthraquinone glycoside as various active compositions such as emodin, physcione, chrysophanol, anthra-glucoside A, anthra-glucoside B; Nature and flavor are bitter, cold, return liver, gallbladder, lung meridian; Energy blood circulation promoting and blood stasis dispelling, dampness removing jaundice eliminating, heat-clearing and toxic substances removing; Zhu Zhi lumps in the chest and abdomen, rheumatic arthralgia, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, injury from falling down, sore swollen toxin etc.; Modern pharmacology proves that Rhizoma Polygoni Cuspidati has the effect such as antibacterial, antiviral, antitumor, antioxidation, blood fat reducing.
Radix Glycyrrhizae: be the root and rhizome of pulse family glycyrrhiza genus Radix Glycyrrhizae, smooth bark Radix Glycyrrhizae, Glycyrrhiza inflata Bat.; Containing triterpene saponin as glycyrrhizin, Glycyrrhiza uralensis Fisch. saponin A, B etc., flavone compound is as 4',7-Dihydroxyflavanone, liquirtin etc., coumarin kind compound is as glycycoumarin, glycyol etc., alkaloids is as quinolines, iloquinoline derivative etc., polysaccharide, as Radix Glycyrrhizae glucosan GBW, Angelica Polysaccharide UA, UB, UC etc., also contains the plurality of active ingredients such as Radix Glycyrrhizae benzofuran, n-tricosane; Radix Glycyrrhizae nature and flavor are sweet, flat, return spleen, stomach, the heart, lung meridian; Can and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Process with controlling weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough, raw with controlling laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, infantile carbuncle and medicine, alimentary toxicosis etc.; Modern pharmacology proves the effects such as Radix Glycyrrhizae has antimicrobial, antiinflammatory, antitussive, eliminates the phlegm, antitumor, mutation, antioxidation, has regulating action to digestive system, cardiovascular system, reproductive system and brain, renal function etc.
Diprophylline: have direct relexation to airway smooth muscle, have expansion bronchus and effect coronarius, its mechanism of action is identical with theophylline; Think by suppressing phosphodiesterase in the past, make caused by intracellular cAMP amount raising, experiment thinks that the bronchiectatic activity part of theophylline is the result because endogenous epinephrine and norepinephrine discharge, in addition, theophylline is purinoceptor blocker, can resist the contraction to respiratory tract such as adenine; Theophylline can strengthen contraction of diaphragm power, and especially when contraction of diaphragm is unable, effect is more remarkable, therefore contributes to improving respiratory function.
Be used for the treatment of a compound traditional Chinese medicine composite for poultry respiratory infection, conventional method can be adopted to be prepared into the common veterinary dosage form such as granule, powder, solution, injection.The present invention only provides a kind of preparation method of granule, comprises the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, extracting in water after section, and filtrate is concentrated into precipitate with ethanol after thick paste, then reclaims ethanol, and it is for subsequent use that spraying dry obtains dry powder; In dry powder, add diprophylline, be mixed and made into soft material, then granulate, dry and get final product.
Described extracting in water, for adding 8 ~ 10 times of water gagings, decocts 1 ~ 1.5 hour, extracts 2 times.
At described filtrate is concentrated into 70 DEG C, relative density is 1.1 ~ 1.3.
Described precipitate with ethanol be add in thick paste concentration be 90 ~ 95% ethanol make alcohol content reach 47 ~ 50%.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Beneficial effect of the present invention:
The present invention adopts Radix Isatidis, Radix Scutellariae, the Radix Astragali, Rhizoma Polygoni Cuspidati, Radix Glycyrrhizae, diprophylline totally 6 kinds of crude drug, wherein Radix Isatidis energy heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, for sore throat, scarlet fever, its infusion has inhibitory action to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, paratyphoid fever bacillus, dysentery (will Hayes, Fu Shi) bacillus, bacillus enteritidis etc., Radix Scutellariae energy heat clearing and damp drying, eliminating fire and detoxication, for hygropyrexia, cough due to lung-heat, Radix Astragali energy enhancing human body immunity function, protect the liver, anti-stress, and there is antibacterial action widely, the phagocytic function of reticuloendothelial system can be strengthened on the one hand, blood leukocytes and multinuclear leucocyte quantity are shown increase, macrophage phagocytic percentage rate and phagocytic index are shown rise, to humoral immunization, cellular immunization all has facilitation, also there is the ability of enhanced virus inducement interferon, as easy catching a cold person takes the Radix Astragali in flu epidemic season, times of common cold not only can be made obviously to reduce, and cold symptoms can be made lighter, shorten the course of disease, on the other hand can also enhancing body anoxia enduring and stress ability, Rhizoma Polygoni Cuspidati energy expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm, for hygropyrexia, cough with copious phlegm, there is antibacterial, antivirus action, the effects such as antitussive and antiasthmatic, a kind of Flavonoid substances contained in Rhizoma Polygoni Cuspidati has inhibitory action to staphylococcus aureus, Staphylococcus albus, Bacillus proteus, and the Rhizoma Polygoni Cuspidati decocting liquid as 10% II type virus (ECHO11) all can have inhibitory action to herpes simplex virus, A type capital, influenza Asia section 68-1 virus and dust, Radix Glycyrrhizae energy invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, for expelling phlegm for arresting cough, relieving spasm to stop pain, because glycyrrhizic acid has the pharmacological action of glucocorticoid sample without serious adverse reaction, clinically be widely used in acute/chronic bronchitis symptom, the glycyrrhizin in addition in Radix Glycyrrhizae or its calcium salt have stronger Detoxication, and the various preparations of glycyrrhizic acid have antiinflammatory action, higher with the activity of succinate, Radix Glycyrrhizae also has phlegm-dispelling functions, can promote throat and bronchial secretion, expectorant is easily brought up, diprophylline is smooth muscle relaxant, has expansion bronchus and effect coronarius, and energy expansion bronchus smooth muscle, keep tubular breathing smooth and easy, the secretions of trachea is excreted, the above-mentioned natural Chinese medicinal herb of compatibility, effect is unique.Above-mentioned 5 taste pure natural Chinese herbal medicine and diprophylline conbined usage can be strengthened effect of prescription therapeutic poultry respiratory infection by the present invention, and drug effect is rapid, evident in efficacy.
The effects such as in prescription of the present invention, Radix Scutellariae cures mainly lung-heat cough with asthma, and the Radix Astragali cures mainly cough due to deficiency of the lung, can improve immunity of organisms, the immune disease-resistance of enhancing body self poison ability, and Rhizoma Polygoni Cuspidati has stronger antibacterial ability, and Radix Glycyrrhizae has antimicrobial, antiinflammatory, antitussive, eliminate the phlegm; The present invention passes through by above-mentioned pure natural Chinese herbal medicine according to monarch principle reasonable formula, then coordinates with diprophylline, and can directly relax airway smooth muscle, and expansion bronchus and coronary artery, have stronger healing ability to poultry respiratory tract diseases.
The present invention adopt pure natural Chinese herbal medicine and diprophylline composite, crude drug is easy to get, cheap and safety, noresidue, without any side effects to poultry body.Above-mentioned compound traditional Chinese medicine composite is prepared into granule by the present invention, and method is simple, easy to operate, is suitable for large-scale production and applies.
Detailed description of the invention
Following embodiment is only described in further detail the present invention, but does not form any limitation of the invention.
Embodiment 1
Be used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, be made up of the crude drug of following parts by weight: Radix Isatidis 25 parts, Radix Scutellariae 30 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 20 parts, 5 parts, Radix Glycyrrhizae, diprophylline 2 parts.
The preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection is used for the treatment of in the present embodiment, comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, section, extracting in water 2 times, first time adds 10 times of water gagings, decoct 1.5 hours, second time adds 8 times of water gagings, decocts 1 hour, collecting decoction, filter, at filtrate is concentrated into 70 DEG C relative density be 1.1 thick paste, add in thick paste concentration be 95% ethanol to alcohol content be 50%, leave standstill, filter, after filtrate recycling ethanol, to obtain dry powder for subsequent use for spraying dry; In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then granulate, dry and get final product.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Embodiment 2
Be used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, be made up of the crude drug of following parts by weight: Radix Isatidis 50 parts, Radix Scutellariae 60 parts, the Radix Astragali 40 parts, Rhizoma Polygoni Cuspidati 40 parts, 10 parts, Radix Glycyrrhizae, diprophylline 3 parts.
The preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection is used for the treatment of in the present embodiment, comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, section, extracting in water 2 times, first time adds 8 times of water gagings, decoct 1 hour, second time adds 8 times of water gagings, decocts 1 hour, collecting decoction, filter, at filtrate is concentrated into 70 DEG C relative density be 1.3 thick paste, add in thick paste concentration be 90% ethanol to alcohol content be 47%, leave standstill, filter, after filtrate recycling ethanol, to obtain dry powder for subsequent use for spraying dry; In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then granulate, dry and get final product.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Embodiment 3
Be used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, be made up of the crude drug of following parts by weight: Radix Isatidis 35 parts, Radix Scutellariae 90 parts, the Radix Astragali 25 parts, Rhizoma Polygoni Cuspidati 60 parts, 8 parts, Radix Glycyrrhizae, diprophylline 2 parts.
The preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection is used for the treatment of in the present embodiment, comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, section, extracting in water 2 times, first time adds 10 times of water gagings, decoct 1 hour, second time adds 8 times of water gagings, decocts 1 hour, collecting decoction, filter, at filtrate is concentrated into 70 DEG C relative density be 1.2 thick paste, add in thick paste concentration be 90% ethanol to alcohol content be 47.5%, leave standstill, filter, after filtrate recycling ethanol, to obtain dry powder for subsequent use for spraying dry; In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then granulate, dry and get final product.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Embodiment 4
Be used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, be made up of the crude drug of following parts by weight: Radix Isatidis 75 parts, Radix Scutellariae 50 parts, the Radix Astragali 60 parts, Rhizoma Polygoni Cuspidati 30 parts, 15 parts, Radix Glycyrrhizae, diprophylline 8 parts.
The preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection is used for the treatment of in the present embodiment, comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, section, extracting in water 2 times, first time adds 10 times of water gagings, decoct 1.5 hours, second time adds 8 times of water gagings, decocts 1.5 hours, collecting decoction, filter, at filtrate is concentrated into 70 DEG C relative density be 1.2 thick paste, add in thick paste concentration be 95% ethanol to alcohol content be 50%, leave standstill, filter, after filtrate recycling ethanol, to obtain dry powder for subsequent use for spraying dry; In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then granulate, dry and get final product.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Embodiment 5
Be used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, be made up of the crude drug of following parts by weight: Radix Isatidis 25 parts, Radix Scutellariae 120 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 100 parts, 5 parts, Radix Glycyrrhizae, diprophylline 10 parts.
The preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection is used for the treatment of in the present embodiment, comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, section, extracting in water 2 times, first time adds 10 times of water gagings, decoct 1.5 hours, second time adds 8 times of water gagings, decocts 1.5 hours, collecting decoction, filter, at filtrate is concentrated into 70 DEG C relative density be 1.2 thick paste, add in thick paste concentration be 95% ethanol to alcohol content be 50%, leave standstill, filter, after filtrate recycling ethanol, to obtain dry powder for subsequent use for spraying dry; In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then granulate, dry and get final product.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Embodiment 6
Be used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection in the present embodiment, be made up of the crude drug of following parts by weight: Radix Isatidis 100 parts, Radix Scutellariae 30 parts, the Radix Astragali 100 parts, Rhizoma Polygoni Cuspidati 20 parts, 20 parts, Radix Glycyrrhizae, diprophylline 2 parts.
The preparation method of the compound traditional Chinese medicine composite of poultry respiratory infection is used for the treatment of in the present embodiment, comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, section, extracting in water 2 times, first time adds 10 times of water gagings, decoct 1 hour, second time adds 8 times of water gagings, decocts 1 hour, collecting decoction, filter, at filtrate is concentrated into 70 DEG C relative density be 1.2 thick paste, add in thick paste concentration be 95% ethanol to alcohol content be 47.5%, leave standstill, filter, after filtrate recycling ethanol, to obtain dry powder for subsequent use for spraying dry; In dry powder, add diprophylline, pulverize, sieve, be mixed and made into soft material, then granulate, dry and get final product.
Usage and consumption: medication is feeding, ampoule is the fowl feeding 1 ~ 2g of every lkg body weight, once-a-day, within 3rd, is a course for the treatment of.
Test example
Experimental animal: according to epidemiology, clinical symptoms, pathology cuts open inspection, identification and isolation of pathogen comprehensive diagnos is bronchitic sick chicken, random selecting 560, be divided into 8 groups, often organize 70, the granule that test group 1 ~ 6 adopts embodiment 1 ~ 6 to prepare successively is treated, matched group adopts commercially available exhaling to breathe heavily peaceful (moistening bio tech ltd purchased from Guangdong), and blank group does not use any medicine, be used in conjunction 3 days, observe the curative effect also adds up healing, effective and invalid number, calculate cure rate, result of the test refers to following table 1.
Curative effect judging standard:
Cure: mental status is good, and do not have chronic respiratory diseases, ataxia situation, bronchus does not have secretions;
Effective: disease is clearly better;
Invalid: mental status is poor, there is sleeping ground not rise, have social phenomenon, have chronic respiratory diseases ataxia phenomenon.
The therapeutic effect that each processed group of table 1 infects chicken respiratory
Conclusion: as can be seen from Table 1, the cure rate of test group 1 ~ 6 when treating chicken respiratory and infecting reaches more than 95%, and matched group is only 61%.Statistical analysis shows, the cure rate of test group is significantly higher than matched group (P < 0.01).Result of the test shows, granule prepared by the embodiment of the present invention 1 ~ 6 infects chicken respiratory and has good therapeutic efficiency.
Claims (7)
1. one kind is used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection, it is characterized in that: the crude drug primarily of following parts by weight forms: Radix Isatidis 20 ~ 100 parts, Radix Scutellariae 20 ~ 120 parts, the Radix Astragali 15 ~ 100 parts, Rhizoma Polygoni Cuspidati 15 ~ 100 parts, 5 ~ 20 parts, Radix Glycyrrhizae, diprophylline 2 ~ 10 parts.
2. the compound traditional Chinese medicine composite being used for the treatment of poultry respiratory infection according to claim 1, is characterized in that: the crude drug primarily of following parts by weight forms: Radix Isatidis 25 ~ 75, Radix Scutellariae 30 ~ 90 parts, the Radix Astragali 20 ~ 60 parts, Rhizoma Polygoni Cuspidati 20 ~ 60 parts, 5 ~ 15 parts, Radix Glycyrrhizae, diprophylline 2 ~ 8 parts.
3. the compound traditional Chinese medicine composite being used for the treatment of poultry respiratory infection according to claim 2, is characterized in that: the crude drug primarily of following parts by weight forms: Radix Isatidis 25 parts, Radix Scutellariae 30 parts, the Radix Astragali 20 parts, Rhizoma Polygoni Cuspidati 20 parts, 5 parts, Radix Glycyrrhizae, diprophylline 2 parts.
4. the preparation method being used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection as described in any one of claim 1-3, it is characterized in that: comprise the following steps: accurately get each taste raw material of Chinese medicine according to parts by weight, extracting in water after section, filtrate is concentrated into precipitate with ethanol after thick paste, reclaim ethanol again, it is for subsequent use that spraying dry obtains dry powder; In dry powder, add diprophylline, be mixed and made into soft material, then granulate, dry and get final product.
5. the preparation method being used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection according to claim 4, is characterized in that: described extracting in water, for adding 8 ~ 10 times of water gagings, decocts 1 ~ 1.5 hour, extracts 2 times.
6. the preparation method being used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection according to claim 4, is characterized in that: at described filtrate is concentrated into 70 DEG C, relative density is 1.1 ~ 1.3.
7. the preparation method being used for the treatment of the compound traditional Chinese medicine composite of poultry respiratory infection according to claim 4, is characterized in that: described precipitate with ethanol be add in thick paste concentration be 90 ~ 95% ethanol make alcohol content reach 47 ~ 50%.
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| CN105232678A (en) * | 2015-11-11 | 2016-01-13 | 郑州后羿制药有限公司 | Traditional Chinese medicine granules capable of increasing egg yield of laying hens and preparing method thereof |
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| CN104208168B (en) | 2016-08-17 |
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Address after: 451162 Zhengzhou economic comprehensive experimentation area, Zhengzhou air port, Henan, Xingang Province Patentee after: Henan Hou Yi Industry Group Co., Ltd. Address before: 451162 Xingang, Henan, Zhengzhou, Hong Kong airport on the eastern side of the road on the eastern side of Zhengzhou Patentee before: Zhengzhou Houyi Pharmaceutical Co., Ltd. |