CN103768153B - Traditional Chinese medicine composition for treating air sacculitis of poultry and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating air sacculitis of poultry and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating air sacculitis of poultry and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention comprises the following raw herbal materials: beehive, liparis nervosa, fig, cortex fraxini, platycodon grandiflorum and liquorice. The traditional Chinese medicine composition for treating air sacculitis of poultry, which is disclosed by the invention, takes the effects of clearing heat, cooling blood, reducing phlegm and detoxifying as the treatment principles and has the advantages of being good in treatment effect and short in treatment time for treating air sacculitis of poultry, and therefore, the death rate of poultries is reduced.
Description
Technical field
The present invention relates to herbal medicine technical field, be particularly a kind ofly used for the treatment of Chinese medicine composition of poultry airsacculitis and preparation method thereof.
Background technology
Poultry airsacculitis occurred comparatively general in recent years, the phenomenon concentrating morbidity is even presented in some cultivation City Regions, chicken group just presents once morbidity that morbidity is serious, the course of disease is long, fatality rate is high, refractory feature, particularly 15 ages in days are more common to the chicken group in the stage of delivering for sale, and spring in time of the year when autumn changes into winter to the coming year is multiple phase of this disease.Airsacculitis is the modal airsacculitis being coli-infection and causing clinically: sick chicken spirit is depressed, and dyspnea, has rale, cough.Cut open the visible air bag of inspection muddy, have a large amount of muddy transudate, severe one airbag wall thickens, and has the cheesy grumeleuse differed in size.Except escherichia coli, the pathogenic microorganism such as Avian pneumo-encephalitis virus, infectious bursa diseases virus, infectious bronchitis pathogenic bacteria, infective rhinitis's virus, mycoplasma, aspergillosis, after infecting broiler, can cause airsacculitis.Because airbag wall is very thin, internal layer is simple squamous epithelium, and being all in opening part is ciliated columnar epithelium, and skin is consecutive simple epithelium with serous coat, and be fibrous connective tissue between two-layer epithelium, containing elastic fiber, not only structure is thin, and blood vessel seldom, very thin.So after airsacculitis occurs, after injection, drinking-water, spice, the absorption of medicine is difficult to reach effective blood drug level, and be difficult to kill to the microorganism on air bag, therefore effect is not bery reliable.And along with the generation of bacterial drug resistance, simple dependence antibiotic can not realize the treatment to airsacculitis.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of easy to use and therapeutic effect and is significantly used for the treatment of Chinese medicine composition of poultry airsacculitis and preparation method thereof.
In order to realize foregoing invention object, the invention provides a kind of Chinese medicine composition being used for the treatment of poultry airsacculitis, described Chinese medicine composition comprises following raw medicinal material: Apis room, Herba Liparidis nervosae, Fructus Fici, Cortex Fraxini, Radix Platycodonis and Radix Glycyrrhizae.
In described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can be preferably: Apis room 15-25 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 12-17 weight portion, Cortex Fraxini 8-16 weight portion, Radix Platycodonis 8-17 weight portion and Radix Glycyrrhizae 15-25 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can be preferably again: Apis room 19 weight portion, Herba Liparidis nervosae 15 weight portion, Fructus Fici 14 weight portion, Cortex Fraxini 12 weight portion, Radix Platycodonis 13 weight portion and Radix Glycyrrhizae 18 weight portion.
Described Chinese medicine composition also comprises Bulbus Lilii, Herba Otteliae Alismoidis, Calculus Equi, Xylocopa dissimilis (Lep.) and Fructus Jujubae.
In described Chinese medicine composition, the parts by weight of each raw medicinal material are preferably: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion, Bulbus Lilii 10-20 weight portion, Herba Otteliae Alismoidis 15-25 weight portion, Calculus Equi 5-20 weight portion, Xylocopa dissimilis (Lep.) 10-25 weight portion and Fructus Jujubae 10-15 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can also be preferably: Apis room 17-26 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 15-20 weight portion, Cortex Fraxini 15-20 weight portion, Radix Platycodonis 5-15 weight portion and Radix Glycyrrhizae 17-30 weight portion, Bulbus Lilii 15-20 weight portion, Herba Otteliae Alismoidis 15-20 weight portion, Calculus Equi 9-20 weight portion, Xylocopa dissimilis (Lep.) 16-25 weight portion and Fructus Jujubae 12-15 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can be preferably again: Apis room 21 weight portion, Herba Liparidis nervosae 15 weight portion, Fructus Fici 17 weight portion, Cortex Fraxini 18 weight portion, Radix Platycodonis 11 weight portion and Radix Glycyrrhizae 23 weight portion, Bulbus Lilii 18 weight portion, Herba Otteliae Alismoidis 17 weight portion, Calculus Equi 14 weight portion, Xylocopa dissimilis (Lep.) 20 weight portion and Fructus Jujubae 13 weight portion.
In order to better realize foregoing invention object, the invention provides a kind of preparation method being used for the treatment of the Chinese medicine composition of poultry airsacculitis, it is characterized in that, described preparation method comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mixing, is crushed to and all by 60 mesh sieves, can obtains ground product;
(2) extraction step: be positioned over by ground product in Chinese medicine extracting tank, adds water by 6 ~ 10 times amount of raw medicinal material gross weight, soaks 6 ~ 12 hours, and then heat to 100 DEG C of extractions 1 ~ 3 hour, filter, obtain extracting solution 1, medicinal residues are for subsequent use; In the Chinese medicine extracting tank holding medicinal residues by raw medicinal material gross weight 6 ~ 10 times amount second time add water, be heated to 80 DEG C ~ 100 DEG C extract 1 ~ 3 hour, filter, obtain extracting solution 2, by extracting solution 1 and extracting solution also 2-in-1, leave standstill;
(3) concentration step: the heating of the extracting solution of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: the present invention for Therapeutic Principle with clearing away heat and cooling blood, removing toxic substances of reducing phlegm, has at treatment poultry airsacculitis the advantage that therapeutic effect is good, treatment time is short, reduces the mortality rate of poultry.
Detailed description of the invention
After poultry airsacculitis occurs, there will be dyspnea, trachea thromboembolism, high heat, whole body diffuse hemorrhage, the prolific phenomenon of various pathogenic microorganism, the present invention is with clearing away heat and cooling blood, removing toxic substances of reducing phlegm for Therapeutic Principle, and with Apis room and Herba Liparidis nervosae for monarch drug, Apis room has heat-clearing and toxic substances removing, anastalsis, Herba Liparidis nervosae has the effect of heat-clearing and toxic substances removing, tonifying the lung removing heat from blood, and both jointly play and alleviate the effect that airsacculitis is hemorrhage, bring down a fever; Cortex Fraxini and Radix Platycodonis are ministerial drug, lung qi dispersing, alleviation bronchial embolization symptom of eliminating the phlegm; Fructus Fici is the herb of Compositae Carpesium plant Herba Carpesii Divaricati and the chrysanthemum of falling lid, and have certain inhibitory action to pathogenic bacteria of drug-resistant, Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription.Under the combined effect of above-mentioned all medicines, the airsacculitis for the treatment of poultry, reduces poultry mortality.
The Chinese medicine composition being used for the treatment of poultry airsacculitis provided by the invention comprises following raw medicinal material: Apis room, Herba Liparidis nervosae, Fructus Fici, Cortex Fraxini, Radix Platycodonis and Radix Glycyrrhizae.
The pharmacological property of each raw medicinal material is as follows:
Apis room: taste is micro-sweet; Cool in nature.Function cures mainly: removing toxic substances and promoting subsidence of swelling; Wind dispelling insecticide.Main sore and toxic; Pharyngalgia is coughed; Chronic rhinitis; Sinusitis; Eczema pruritus; Skin ulcer tinea.
Herba Liparidis nervosae: bitter, cold.Function cures mainly: heat clearing away, removing heat from blood, hemostasis.For lung-heat spitting of blood, spit blood; Wound hemorrhage is controlled in external, furuncle toxic swelling.
Fructus Fici: sweet is flat.Function cures mainly: invigorating the stomach and promoting bowel movement, subduing swelling and detoxicating.Control enteritis, dysentery, constipation, hemorrhoid, laryngalgia, carbuncle skin ulcer scabies, throat, appetizing anthelmintic.For inappetence, abdominal distention, constipation due to hemorrhoids, dyspepsia, hemorrhoid, proctoptosis, diarrhoea, hypogalactia, laryngopharynx swelling and pain, hematodiarrhoea, the diseases such as cough ant phlegm.
Cortex Fraxini: cure mainly heat clearing and damp drying, liver heat removing and eyesight improving, antiasthmatic-antitussive.For pyretic toxicity dysentery, conjunctival congestion and swelling pain, the raw cataracta of order.
Radix Platycodonis: be the dried roots of Campanulaceae Radix Platycodonis, bitter in the mouth, pungent, slightly warm in nature.Enter lung meridian.Energy expelling phlegm for arresting cough, and have lung qi dispersing, evacuation of pus effect.Contained platycodin is to the direct stimulation of oral cavity, throat, gastric mucosa, and reflexive ground increases bronchial mucosa hypersecretion thus sputum is diluted, and is easy to discharge; Radix Platycodonis has antitussive effect, and have and strengthen antiinflammatory and immunization, its antiinflammatory intensity is similar to aspirin; Water extract can strengthen the phagocytic function of macrophage, strengthens the sterilizing power of neutrophilic leukocyte, improves lysozyme activity; Preventive effect is had to stress ulcer.The thick saponin of Radix Platycodonis has calmness, analgesia, refrigeration function, again can blood sugar lowering, cholesterol reducing, relaxing smooth muscle.Platycodin has very strong haemolysis, but oral can decomposition in digestive tract destroys and lose haemolysis.
Radix Glycyrrhizae: property is put down, and sweet in the mouth, returns 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strongly have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic so that the pharmacological action such as anticancer, Radix Glycyrrhizae has blood fat reducing, antioxidative effect.
In order to better treat poultry airsacculitis, Chinese medicine composition of the present invention also comprises: Bulbus Lilii, Herba Otteliae Alismoidis, Calculus Equi, Xylocopa dissimilis (Lep.) and Fructus Jujubae.
Bulbus Lilii: bitter in the mouth, cold nature.Enter the heart, lung meridian.Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, absentminded.There is nourishing YIN and moistening the lung cough-relieving effect, for the cough caused by dryness-heat of deficiency of lung-YIN, as all sorts of flowers cream.Control chronic cough of deficiency lung, chronic cough is spat blood, as baihe gujin decoction.Have clearing away heart-fire for tranquillization effect, unclear for calentura waste heat, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep etc.
Herba Otteliae Alismoidis: sweet, light, cool.Function cures mainly: removing heat-phlegm, removing toxic substances diuresis.For cough due to lung-heat, pulmonary tuberculosis, hemoptysis, asthma, edema, dysuria; Carbuncle is controlled in external, burn and scald.
Calculus Equi: sweet, salty, micro-hardship is cool.Function cures mainly: removing heat-phlegm, tranquillizing the mind by relieving convulsion.For epilepsy, convulsion in childhood, carbuncle sore tumefacting virus.
Xylocopa dissimilis (Lep.): sweet, sour, cold.Function cures mainly: clearing away heat-fire, dispels the wind.To hide worm worm, aphtha, pharyngalgia for tooth, infantile convulsion.
Fructus Jujubae: there is immunosuppressive action, the ethanol extract of Fructus Jujubae with every day 100mg to rat oral gavage, display Fructus Jujubae has same immunosuppressant with azathioprine; The generation of antibody can be suppressed to atopic diseases.Fructus Jujubae ethanol extract may have inhibitory action to rat reactive antibody, and other effects of inhibitory action are not produced to non-reacted antibody: the two glucoside A of the flavone in Fructus Jujubae, pharmacological evaluation proves have calmness, hypnosis and hypotensive effect, and Fructus Jujubae has the effect increasing cAMP in leukocyte.Fructus Jujubae decoct can reduce the damage of CCl4 to Rabbit Liver.The swimming time of mice can be extended.Nearest report Fructus Jujubae has the proliferation function of anticancer.
Embodiment 1 powder 1
Embodiments provide a kind of Chinese medicine composition being used for the treatment of poultry airsacculitis, wherein, in Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 19 weight portion, Herba Liparidis nervosae 15 weight portion, Fructus Fici 14 weight portion, Cortex Fraxini 12 weight portion, Radix Platycodonis 13 weight portion and Radix Glycyrrhizae 18 weight portion.
The preparation method of above-mentioned Chinese medicine composition comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mixing, is crushed to and all by 60 mesh sieves, can obtains ground product;
(2) extraction step: be positioned over by ground product in Chinese medicine extracting tank, adds water by 8 times amount of raw medicinal material gross weight, soaks 9 hours, and then heat to 100 DEG C of extractions 2 hours, filter, obtain extracting solution 1, medicinal residues are for subsequent use; In the Chinese medicine extracting tank holding medicinal residues by raw medicinal material gross weight 7 times amount second time add water, be heated to 90 DEG C extract 3 hours, filter, obtain extracting solution 2, by extracting solution 1 and extracting solution also 2-in-1, leave standstill;
(3) concentration step: the heating of the extracting solution of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
Embodiment 2 powder 2
Embodiments provide a kind of Chinese medicine composition being used for the treatment of poultry airsacculitis, wherein, in Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 21 weight portion, Herba Liparidis nervosae 15 weight portion, Fructus Fici 17 weight portion, Cortex Fraxini 18 weight portion, Radix Platycodonis 11 weight portion and Radix Glycyrrhizae 23 weight portion, Bulbus Lilii 18 weight portion, Herba Otteliae Alismoidis 17 weight portion, Calculus Equi 14 weight portion, Xylocopa dissimilis (Lep.) 20 weight portion and Fructus Jujubae 13 weight portion.
The preparation method of above-mentioned Chinese medicine composition comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mixing, is crushed to and all by 60 mesh sieves, can obtains ground product;
(2) extraction step: be positioned over by ground product in Chinese medicine extracting tank, adds water by 9 times amount of raw medicinal material gross weight, soaks 11 hours, and then heat to 100 DEG C of extractions 3 hours, filter, obtain extracting solution 1, medicinal residues are for subsequent use; In the Chinese medicine extracting tank holding medicinal residues by raw medicinal material gross weight 8 times amount second time add water, be heated to 100 DEG C extract 3 hours, filter, obtain extracting solution 2, by extracting solution 1 and extracting solution also 2-in-1, leave standstill;
(3) concentration step: the heating of the extracting solution of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
Toxicity test
Select SD rat, give the powder of the embodiment of the present invention 2 of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, within after last administration 24 hours, respectively group is alive kills 1/2 animal (male and female half and half), and all the other 1/2 animals continue observations 2 weeks rear living and kill.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal, within after administration 90 days, within 2 weeks, carries out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, connect administration in 90 days according to result of the test Chinese medicine preparation of the present invention at high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) to have no significant effect rat, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention higher.
Application test and effect
1, in order to verify the effect of Chinese medicine composition of the present invention to treatment poultry airsacculitis, testing, contrasting with conventional medicament, studying its therapeutic effect, testing and carry out at certain chicken house of Shandong Shangqiu City.This chicken house 20 Day-old Broiler Chickens of in December, 2012 occurs dead, and dissect and find, tracheal strips has yellow embolus, and air bag is muddy, pulmonary's large-area hemorrhage, and other chickens occur that spirit is depressed, and the symptoms such as dyspnea, has rale, cough are airsacculitis after diagnosing.Selecting 1200 ill chickens is experimental subject, be divided into three experimental grouies at random, three groups of sick chickens comparing difference not statistically significant in state of an illness weight, each experimental group 400, uses the powder 1(embodiment group one of embodiment 1 respectively), the powder 2(embodiment group two of embodiment 2) and conventional medicament (matched group) treat.The using method of powder 1 and powder 2 is: every 100g powder is watered 200kg, and use 4 days continuously, conventional medicament selects Nuo Dakang, and using method, for be dissolved in drinking water by Nuo Dakang, uses 4 days continuously.Test is 8 days, note every day observing and record the situation of chicken, comprising the mental status, search for food, breathing situation, death etc.Test the 5th day statistics mortality rate and effective percentage, the chicken of not fully recovering proceeds treatment from test the 6th day, add up mortality rate and effective percentage after off-test.Wherein effective percentage is that the summation of recovery from illness number of the significant figure that takes a turn for the better of symptom and recovery from illness accounts for the percentage ratio testing total chicken number.Result as shown in Table 1 and Table 2.
The 5th day each experimental group curative effect comparision table tested by table 1
Each experimental group curative effect comparision table after table 2 off-test
from the data of table 1 with table 2: compared with conventional medicament, use the medicine of the embodiment of the present invention 1 and embodiment 2 to carry out treating chicken airsacculitis and there is the advantage that therapeutic effect is good, healing time is short and reduce chicken mortality rate.
2, the foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (7)
1. be used for the treatment of the Chinese medicine composition of poultry airsacculitis, it is characterized in that, described Chinese medicine composition is made up of the raw medicinal material of following parts by weight: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion.
2. the Chinese medicine composition being used for the treatment of poultry airsacculitis according to claim 1, it is characterized in that, described Chinese medicine composition is made up of the raw medicinal material of following parts by weight: Apis room 15-25 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 12-17 weight portion, Cortex Fraxini 8-16 weight portion, Radix Platycodonis 8-17 weight portion and Radix Glycyrrhizae 15-25 weight portion.
3. the Chinese medicine composition being used for the treatment of poultry airsacculitis according to claim 1, it is characterized in that, described Chinese medicine composition is made up of the raw medicinal material of following parts by weight: Apis room 19 weight portion, Herba Liparidis nervosae 15 weight portion, Fructus Fici 14 weight portion, Cortex Fraxini 12 weight portion, Radix Platycodonis 13 weight portion and Radix Glycyrrhizae 18 weight portion.
4. be used for the treatment of the Chinese medicine composition of poultry airsacculitis, it is characterized in that, described Chinese medicine composition is made up of the raw medicinal material of following parts by weight: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion, Bulbus Lilii 10-20 weight portion, Herba Otteliae Alismoidis 15-25 weight portion, Calculus Equi 5-20 weight portion, Xylocopa dissimilis (Lep.) 10-25 weight portion and Fructus Jujubae 10-15 weight portion.
5. the Chinese medicine composition being used for the treatment of poultry airsacculitis according to claim 4, it is characterized in that, described Chinese medicine composition is made up of the raw medicinal material of following parts by weight: Apis room 17-26 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 15-20 weight portion, Cortex Fraxini 15-20 weight portion, Radix Platycodonis 5-15 weight portion and Radix Glycyrrhizae 17-30 weight portion, Bulbus Lilii 15-20 weight portion, Herba Otteliae Alismoidis 15-20 weight portion, Calculus Equi 9-20 weight portion, Xylocopa dissimilis (Lep.) 16-25 weight portion and Fructus Jujubae 12-15 weight portion.
6. the Chinese medicine composition being used for the treatment of poultry airsacculitis according to claim 4, it is characterized in that, described Chinese medicine composition is made up of the raw medicinal material of following parts by weight: Apis room 21 weight portion, Herba Liparidis nervosae 15 weight portion, Fructus Fici 17 weight portion, Cortex Fraxini 18 weight portion, Radix Platycodonis 11 weight portion and Radix Glycyrrhizae 23 weight portion, Bulbus Lilii 18 weight portion, Herba Otteliae Alismoidis 17 weight portion, Calculus Equi 14 weight portion, Xylocopa dissimilis (Lep.) 20 weight portion and Fructus Jujubae 13 weight portion.
7. the preparation method being used for the treatment of the Chinese medicine composition of poultry airsacculitis as described in any one of claim 1-6, is characterized in that, described preparation method comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mixing, is crushed to and all by 60 mesh sieves, can obtains ground product;
(2) extraction step: be positioned over by ground product in Chinese medicine extracting tank, adds water by 6 ~ 10 times amount of raw medicinal material gross weight, soaks 6 ~ 12 hours, and then heat to 100 DEG C of extractions 1 ~ 3 hour, filter, obtain extracting solution 1, medicinal residues are for subsequent use; In the Chinese medicine extracting tank holding medicinal residues by raw medicinal material gross weight 6 ~ 10 times amount second time add water, be heated to 80 DEG C ~ 100 DEG C extract 1 ~ 3 hour, filter, obtain extracting solution 2, by extracting solution 1 and extracting solution also 2-in-1, leave standstill;
(3) concentration step: the heating of the extracting solution of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
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