CN103768153A - Traditional Chinese medicine composition for treating air sacculitis of poultry and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating air sacculitis of poultry and preparation method thereof Download PDF

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CN103768153A
CN103768153A CN201410053939.4A CN201410053939A CN103768153A CN 103768153 A CN103768153 A CN 103768153A CN 201410053939 A CN201410053939 A CN 201410053939A CN 103768153 A CN103768153 A CN 103768153A
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CN103768153B (en
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李鑫
张一帆
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Shandong New Hope Liuhe Group Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine composition for treating air sacculitis of poultry and a preparation method thereof. The traditional Chinese medicine composition disclosed by the invention comprises the following raw herbal materials: beehive, liparis nervosa, fig, cortex fraxini, platycodon grandiflorum and liquorice. The traditional Chinese medicine composition for treating air sacculitis of poultry, which is disclosed by the invention, takes the effects of clearing heat, cooling blood, reducing phlegm and detoxifying as the treatment principles and has the advantages of being good in treatment effect and short in treatment time for treating air sacculitis of poultry, and therefore, the death rate of poultries is reduced.

Description

Be used for the treatment of Chinese medicine composition of poultry airsacculitis and preparation method thereof
Technical field
The present invention relates to herbal medicine technical field, particularly a kind of Chinese medicine composition that is used for the treatment of poultry airsacculitis and preparation method thereof.
Background technology
Poultry airsacculitis occurred comparatively general in recent years, even present in some cultivation City Regions the phenomenon of concentrating morbidity, once chicken group morbidity just presents, morbidity is serious, the course of disease is long, fatality rate is high, refractory feature, particularly 15 ages in days are more common to the chicken group in the stage of delivering for sale, and be the multiple phase of this disease spring in time of the year when autumn changes into winter to the coming year.Airsacculitis is modal is clinically the airsacculitis that coli-infection causes: sick chicken spirit is depressed, and dyspnea, has rale, cough.Cut open the visible air bag muddiness of inspection, have the transudate of a large amount of muddinesses, severe one airbag wall thickens, and has the cheesy grumeleuse differing in size.Except escherichia coli, the pathogenic microorganisms such as Avian pneumo-encephalitis virus, infectious bursa diseases virus, infectious bronchitis pathogenic bacteria, infective rhinitis's virus, mycoplasma, aspergillosis, infect after broiler, can cause airsacculitis.Because airbag wall is very thin, internal layer is simple squamous epithelium, and being all in opening part is cilium columnar epithelium, and skin is and the consecutive simple epithelium of serous coat, between two-layer epithelium, is fibrous connective tissue, contains elastic fiber, and not only structure is thin, and blood vessel seldom, very thin.So after airsacculitis occurs, after injection, drinking-water, spice, the absorption of medicine is difficult to reach effective blood drug level, and the microorganism on air bag is difficult to kill, therefore effect is not bery reliable.And along with the generation of bacterial drug resistance, rely on merely antibiotic can not realize the treatment to airsacculitis.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of easy to use and therapeutic effect and is significantly used for the treatment of Chinese medicine composition of poultry airsacculitis and preparation method thereof.
In order to realize foregoing invention object, the invention provides a kind of Chinese medicine composition that is used for the treatment of poultry airsacculitis, described Chinese medicine composition comprises following raw medicinal material: Apis room, Herba Liparidis nervosae, Fructus Fici, Cortex Fraxini, Radix Platycodonis and Radix Glycyrrhizae.
In described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can be preferably: Apis room 15-25 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 12-17 weight portion, Cortex Fraxini 8-16 weight portion, Radix Platycodonis 8-17 weight portion and Radix Glycyrrhizae 15-25 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can be preferably again: Apis room 19 weight portions, Herba Liparidis nervosae 15 weight portions, Fructus Fici 14 weight portions, Cortex Fraxini 12 weight portions, Radix Platycodonis 13 weight portions and Radix Glycyrrhizae 18 weight portions.
Described Chinese medicine composition also comprises Bulbus Lilii, Herba Otteliae Alismoidis, Calculus Equi, Xylocopa dissimilis (Lep.) and Fructus Jujubae.
In described Chinese medicine composition, the parts by weight of each raw medicinal material are preferably: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion, Bulbus Lilii 10-20 weight portion, Herba Otteliae Alismoidis 15-25 weight portion, Calculus Equi 5-20 weight portion, Xylocopa dissimilis (Lep.) 10-25 weight portion and Fructus Jujubae 10-15 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can also be preferably: Apis room 17-26 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 15-20 weight portion, Cortex Fraxini 15-20 weight portion, Radix Platycodonis 5-15 weight portion and Radix Glycyrrhizae 17-30 weight portion, Bulbus Lilii 15-20 weight portion, Herba Otteliae Alismoidis 15-20 weight portion, Calculus Equi 9-20 weight portion, Xylocopa dissimilis (Lep.) 16-25 weight portion and Fructus Jujubae 12-15 weight portion.
In described Chinese medicine composition, the parts by weight of each raw medicinal material can be preferably again: Apis room 21 weight portions, Herba Liparidis nervosae 15 weight portions, Fructus Fici 17 weight portions, Cortex Fraxini 18 weight portions, Radix Platycodonis 11 weight portions and Radix Glycyrrhizae 23 weight portions, Bulbus Lilii 18 weight portions, Herba Otteliae Alismoidis 17 weight portions, Calculus Equi 14 weight portions, Xylocopa dissimilis (Lep.) 20 weight portions and Fructus Jujubae 13 weight portions.
In order better to realize foregoing invention object, the invention provides a kind of preparation method of the Chinese medicine composition that is used for the treatment of poultry airsacculitis, it is characterized in that, described preparation method comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mix, be crushed to and can, all by 60 mesh sieves, obtain ground product;
(2) extraction step: ground product is positioned in Chinese medicine extracting tank, adds water by 6~10 times of amounts of raw medicinal material gross weight, soak 6~12 hours, then heat to 100 ℃ of extractions 1~3 hour, filter, obtain extracting solution 1, medicinal residues are for subsequent use; 6~10 times of flow control secondaries by raw medicinal material gross weight in the Chinese medicine extracting tank that holds medicinal residues add water, and are heated to 80 ℃~100 ℃ and extract 1~3 hour, filter, and obtain extracting solution 2, and extracting solution 1 and extracting solution 2 are merged, and leave standstill;
(3) concentration step: the extracting solution heating of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: the present invention, take clearing away heat and cooling blood, the removing toxic substances of reducing phlegm as Therapeutic Principle, has advantages of that at treatment poultry airsacculitis therapeutic effect is good, treatment time is short, reduces the mortality rate of poultry.
The specific embodiment
After poultry airsacculitis occurs, there will be dyspnea, trachea thromboembolism, high heat, whole body diffuse hemorrhage, the prolific phenomenon of various pathogenic microorganisms, the present invention is take clearing away heat and cooling blood, the removing toxic substances of reducing phlegm as Therapeutic Principle, and take Apis room and Herba Liparidis nervosae as monarch drug, Apis room has heat-clearing and toxic substances removing, anastalsis, Herba Liparidis nervosae has the effect of heat-clearing and toxic substances removing, tonifying the lung removing heat from blood, and both jointly play and alleviate the effect that airsacculitis is hemorrhage, bring down a fever; Cortex Fraxini and Radix Platycodonis are ministerial drug, lung qi dispersing, the alleviation bronchial embolization symptom of eliminating the phlegm; Fructus Fici is Compositae Carpesium plant Herba Carpesii Divaricati and covers the herb of chrysanthemum, and pathogenic bacteria of drug-resistant is had to certain inhibitory action, and Radix Glycyrrhizae can coordinating the actions of various ingredients in a prescription.Under the combined effect of above-mentioned all medicines, the airsacculitis for the treatment of poultry, reduces poultry mortality.
The Chinese medicine composition that is used for the treatment of poultry airsacculitis provided by the invention comprises following raw medicinal material: Apis room, Herba Liparidis nervosae, Fructus Fici, Cortex Fraxini, Radix Platycodonis and Radix Glycyrrhizae.
The pharmacological property of each raw medicinal material is as follows:
Apis room: taste is micro-sweet; Cool in nature.Function cures mainly: removing toxic substances and promoting subsidence of swelling; Wind dispelling insecticide.Main sore and toxic; Pharyngalgia cough; Chronic rhinitis; Sinusitis; Eczema pruritus; Skin ulcer tinea.
Herba Liparidis nervosae: hardship, cold.Function cures mainly: heat clearing away, removing heat from blood, hemostasis.For lung-heat spitting of blood, spit blood; Wound hemorrhage is controlled in external, furuncle toxic swelling.
Fructus Fici: sweet, flat.Function cures mainly: invigorating the stomach and promoting bowel movement, subduing swelling and detoxicating.Control enteritis, dysentery, constipation, hemorrhoid, laryngalgia, carbuncle skin ulcer scabies, throat, appetizing anthelmintic.For inappetence, abdominal distention, constipation due to hemorrhoids, dyspepsia, hemorrhoid, proctoptosis, diarrhoea, hypogalactia, laryngopharynx swelling and pain, hematodiarrhoea, the diseases such as cough ant phlegm.
Cortex Fraxini: cure mainly heat clearing and damp drying, liver heat removing and eyesight improving, antiasthmatic-antitussive.For pyretic toxicity dysentery, conjunctival congestion and swelling pain, the raw cataracta of order.
Radix Platycodonis: be the dried roots of Campanulaceae Radix Platycodonis, bitter in the mouth, pungent, slightly warm in nature.Enter lung meridian.Energy expelling phlegm for arresting cough, and have lung qi dispersing, evacuation of pus effect.The direct stimulation of contained platycodin to oral cavity, throat, gastric mucosa, makes sputum dilution thereby reflexive ground increases bronchial mucosa hypersecretion, is easy to discharge; Radix Platycodonis has antitussive effect, has the antiinflammatory of enhancing and immunization, and its antiinflammatory intensity is similar to aspirin; Water extract can strengthen the phagocytic function of macrophage, strengthens the sterilizing power of neutrophilic leukocyte, improves lysozyme activity; Stress ulcer is had to preventive effect.The thick saponin of Radix Platycodonis has calmness, analgesia, refrigeration function, again can blood sugar lowering, cholesterol reducing, and relaxing smooth muscle.Platycodin has very strong haemolysis, but destroy and lose haemolysis oral can decomposition in digestive tract.
Radix Glycyrrhizae: property is flat, and sweet in the mouth, returns 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strongly have removing toxic substances, eliminate the phlegm, pain relieving, spasmolytic be so that the pharmacological action such as anticancer, Radix Glycyrrhizae has blood fat reducing, antioxidative effect.
In order better to treat poultry airsacculitis, Chinese medicine composition of the present invention also comprises: Bulbus Lilii, Herba Otteliae Alismoidis, Calculus Equi, Xylocopa dissimilis (Lep.) and Fructus Jujubae.
Bulbus Lilii: bitter in the mouth, cold nature.Enter the heart, lung meridian.Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep, absentminded.There is nourishing YIN and moistening the lung cough-relieving effect, for the cough caused by dryness-heat of deficiency of lung-YIN, as all sorts of flowers cream.Control chronic cough of deficiency lung, chronic cough spitting of blood, as baihe gujin decoction.There is clearing away heart-fire for tranquillization effect, unclear for calentura waste heat, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep etc.
Herba Otteliae Alismoidis: sweet, light, cool.Function cures mainly: removing heat-phlegm, removing toxic substances diuresis.For cough due to lung-heat, pulmonary tuberculosis, hemoptysis, asthma, edema, dysuria; Carbuncle is controlled in external, burn and scald.
Calculus Equi: sweet, salty, micro-hardship, cool.Function cures mainly: removing heat-phlegm, tranquillizing the mind by relieving convulsion.For epilepsy, children's twitches, carbuncle sore tumefacting virus.
Xylocopa dissimilis (Lep.): sweet, sour, cold.Function cures mainly: clearing away heat-fire, dispels the wind.For tooth hide worm worm, aphtha, pharyngalgia, infantile convulsion.
Fructus Jujubae: there is immunosuppressive action, the ethanol extract of Fructus Jujubae with every day 100mg to rat oral gavage, show Fructus Jujubae there is same immunosuppressant with azathioprine; Can suppress the generation of antibody to atopic diseases.Fructus Jujubae ethanol extract may have inhibitory action to rat reactive antibody, and non-reacted antibody is not produced to other effects of inhibitory action: the two glucoside A of flavone in Fructus Jujubae, pharmacological evaluation proves to have calmness, hypnosis and hypotensive effect, Fructus Jujubae to have the effect that increases cAMP in leukocyte.Fructus Jujubae decoct can reduce the damage of CCl4 to Rabbit Liver.Can extend the swimming time of mice.Report Fructus Jujubae has the proliferation function of anticancer recently.
Embodiment 1 powder 1
The embodiment of the present invention provides a kind of Chinese medicine composition that is used for the treatment of poultry airsacculitis, wherein, in Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 19 weight portions, Herba Liparidis nervosae 15 weight portions, Fructus Fici 14 weight portions, Cortex Fraxini 12 weight portions, Radix Platycodonis 13 weight portions and Radix Glycyrrhizae 18 weight portions.
The preparation method of above-mentioned Chinese medicine composition comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mix, be crushed to and can, all by 60 mesh sieves, obtain ground product;
(2) extraction step: ground product is positioned in Chinese medicine extracting tank, adds water by 8 times of amounts of raw medicinal material gross weight, soak 9 hours, then heat to 100 ℃ of extractions 2 hours, filter, obtain extracting solution 1, medicinal residues are for subsequent use; 7 times of flow control secondaries by raw medicinal material gross weight in the Chinese medicine extracting tank that holds medicinal residues add water, and are heated to 90 ℃ and extract 3 hours, filter, and obtain extracting solution 2, and extracting solution 1 and extracting solution 2 are merged, and leave standstill;
(3) concentration step: the extracting solution heating of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
Embodiment 2 powder 2
The embodiment of the present invention provides a kind of Chinese medicine composition that is used for the treatment of poultry airsacculitis, wherein, in Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 21 weight portions, Herba Liparidis nervosae 15 weight portions, Fructus Fici 17 weight portions, Cortex Fraxini 18 weight portions, Radix Platycodonis 11 weight portions and Radix Glycyrrhizae 23 weight portions, Bulbus Lilii 18 weight portions, Herba Otteliae Alismoidis 17 weight portions, Calculus Equi 14 weight portions, Xylocopa dissimilis (Lep.) 20 weight portions and Fructus Jujubae 13 weight portions.
The preparation method of above-mentioned Chinese medicine composition comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mix, be crushed to and can, all by 60 mesh sieves, obtain ground product;
(2) extraction step: ground product is positioned in Chinese medicine extracting tank, adds water by 9 times of amounts of raw medicinal material gross weight, soak 11 hours, then heat to 100 ℃ of extractions 3 hours, filter, obtain extracting solution 1, medicinal residues are for subsequent use; 8 times of flow control secondaries by raw medicinal material gross weight in the Chinese medicine extracting tank that holds medicinal residues add water, and are heated to 100 ℃ and extract 3 hours, filter, and obtain extracting solution 2, and extracting solution 1 and extracting solution 2 are merged, and leave standstill;
(3) concentration step: the extracting solution heating of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
Toxicity test
Select SD rat, give the powder of the embodiment of the present invention 2 of variable concentrations (18.0,6.0,2.0g crude drug/kg), every day gavage once, continuous 90 days, after last administration, 24 hours each groups are lived and are killed 1/2 animal (male and female half and half), and all the other 1/2 animals continue observation and live and kill after 2 weeks.Duration of test is observed outward appearance, general behavior, food ration, the body weight change of animal, and after administration, the index checkings such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crca, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology are carried out in 90 days and drug withdrawal for 2 weeks.Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight gain are all without ANOMALOUS VARIATIONS; Three dosage groups and matched group hematological examination, blood biochemical are learned, urine biochemical analysis is all in normal range, between group without significant difference; Each group main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also has no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, connecting administration in 90 days according to result of the test Chinese medicine preparation of the present invention at high, medium and low three dosage (18.0,6.0,2.0g crude drug/kg) has no significant effect rat, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dosage safety of Chinese medicine preparation clinical practice of the present invention higher.
Application test and effect
1, in order to verify the effect of Chinese medicine composition of the present invention to treatment poultry airsacculitis, test, contrast with conventional medicament, study its therapeutic effect, test is carried out at certain chicken house of Shandong Shangqiu City.2012 there is death in these chicken house 20 Day-old Broiler Chickens of December, dissect and find, have yellow embolus in trachea, air bag muddiness, and pulmonary's large-area hemorrhage, there is the symptoms such as spirit is depressed, and dyspnea, has rale, cough in other chickens, is airsacculitis after diagnosing.Selecting 1200 ill chickens is experimental subject, be divided at random three experimental grouies, three groups of sick chickens comparing difference not statistically significant aspect state of an illness weight, 400 of each experimental grouies, use respectively the powder 1(embodiment group one of embodiment 1), the powder 2(embodiment group two of embodiment 2) and conventional medicament (matched group) treat.The using method of powder 1 and powder 2 is: every 100g powder is watered 200kg, uses continuously 4 days, and conventional medicament is selected Nuo Dakang, and using method, for Nuo Dakang is dissolved in drinking water, is used 4 days continuously.Test is 8 days, notes observing and recording the situation of chicken every day, comprises the mental status, searches for food, breathing situation, death etc.Test and within the 5th day, add up mortality rate and effective percentage, the chicken of recovery from illness does not start to proceed treatment on the 6th day from testing, and adds up mortality rate and effective percentage after off-test.Wherein effective percentage is the percentage ratio that the summation of the significant figure that takes a turn for the better of symptom and the recovery from illness number of recovery from illness accounts for the total chicken number of test.Result as shown in Table 1 and Table 2.
Table 1 is tested the 5th day each experimental group curative effect comparision table
Figure 340093DEST_PATH_IMAGE001
Each experimental group curative effect comparision table after table 2 off-test
Figure 672985DEST_PATH_IMAGE002
?data from table 1 and table 2: compared with conventional medicament, the medicine of the use embodiment of the present invention 1 and embodiment 2 is treated chicken airsacculitis and had advantages of that therapeutic effect is good, healing time is short and reduce chicken mortality rate.
2, the foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (9)

1. the Chinese medicine composition that is used for the treatment of poultry airsacculitis, is characterized in that, described Chinese medicine composition comprises following raw medicinal material: Apis room, Herba Liparidis nervosae, Fructus Fici, Cortex Fraxini, Radix Platycodonis and Radix Glycyrrhizae.
2. the Chinese medicine composition that is used for the treatment of poultry airsacculitis according to claim 1, it is characterized in that, in described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion.
3. the Chinese medicine composition that is used for the treatment of poultry airsacculitis according to claim 1 and 2, it is characterized in that, in described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 15-25 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 12-17 weight portion, Cortex Fraxini 8-16 weight portion, Radix Platycodonis 8-17 weight portion and Radix Glycyrrhizae 15-25 weight portion.
4. according to the Chinese medicine composition that is used for the treatment of poultry airsacculitis described in claim 1-3 any one, it is characterized in that, in described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 19 weight portions, Herba Liparidis nervosae 15 weight portions, Fructus Fici 14 weight portions, Cortex Fraxini 12 weight portions, Radix Platycodonis 13 weight portions and Radix Glycyrrhizae 18 weight portions.
5. according to the Chinese medicine composition that is used for the treatment of poultry airsacculitis described in claim 1-4 any one, it is characterized in that, described Chinese medicine composition also comprises Bulbus Lilii, Herba Otteliae Alismoidis, Calculus Equi, Xylocopa dissimilis (Lep.) and Fructus Jujubae.
6. according to the Chinese medicine composition that is used for the treatment of poultry airsacculitis described in claim 1-5 any one, it is characterized in that, in described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 10-30 weight portion, Herba Liparidis nervosae 10-20 weight portion, Fructus Fici 10-20 weight portion, Cortex Fraxini 5-20 weight portion, Radix Platycodonis 5-20 weight portion and Radix Glycyrrhizae 10-30 weight portion, Bulbus Lilii 10-20 weight portion, Herba Otteliae Alismoidis 15-25 weight portion, Calculus Equi 5-20 weight portion, Xylocopa dissimilis (Lep.) 10-25 weight portion and Fructus Jujubae 10-15 weight portion.
7. according to the Chinese medicine composition that is used for the treatment of poultry airsacculitis described in claim 1-6 any one, it is characterized in that, in described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 17-26 weight portion, Herba Liparidis nervosae 13-18 weight portion, Fructus Fici 15-20 weight portion, Cortex Fraxini 15-20 weight portion, Radix Platycodonis 5-15 weight portion and Radix Glycyrrhizae 17-30 weight portion, Bulbus Lilii 15-20 weight portion, Herba Otteliae Alismoidis 15-20 weight portion, Calculus Equi 9-20 weight portion, Xylocopa dissimilis (Lep.) 16-25 weight portion and Fructus Jujubae 12-15 weight portion.
8. according to the Chinese medicine composition that is used for the treatment of poultry airsacculitis described in claim 1-7 any one, it is characterized in that, in described Chinese medicine composition, the parts by weight of each raw medicinal material are: Apis room 21 weight portions, Herba Liparidis nervosae 15 weight portions, Fructus Fici 17 weight portions, Cortex Fraxini 18 weight portions, Radix Platycodonis 11 weight portions and Radix Glycyrrhizae 23 weight portions, Bulbus Lilii 18 weight portions, Herba Otteliae Alismoidis 17 weight portions, Calculus Equi 14 weight portions, Xylocopa dissimilis (Lep.) 20 weight portions and Fructus Jujubae 13 weight portions.
9. a preparation method for the Chinese medicine composition that is used for the treatment of poultry airsacculitis as described in claim 1-8 any one, is characterized in that, described preparation method comprises the following steps:
(1) pulverising step: take all raw medicinal materials according to ratio of weight and number, mix, be crushed to and can, all by 60 mesh sieves, obtain ground product;
(2) extraction step: ground product is positioned in Chinese medicine extracting tank, adds water by 6~10 times of amounts of raw medicinal material gross weight, soak 6~12 hours, then heat to 100 ℃ of extractions 1~3 hour, filter, obtain extracting solution 1, medicinal residues are for subsequent use; 6~10 times of flow control secondaries by raw medicinal material gross weight in the Chinese medicine extracting tank that holds medicinal residues add water, and are heated to 80 ℃~100 ℃ and extract 1~3 hour, filter, and obtain extracting solution 2, and extracting solution 1 and extracting solution 2 are merged, and leave standstill;
(3) concentration step: the extracting solution heating of merging is concentrated into pasty state, puts into drying in oven, grind to form fine-powdered after cooling, obtain powder.
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CN104083508A (en) * 2014-07-16 2014-10-08 葛洪伟 Preparation method of traditional Chinese medicine preparation for preventing and treating respiratory disease caused by chicken airbag inflammation
CN105833161A (en) * 2016-04-30 2016-08-10 何佑兵 Pharmaceutical composition for preventing and treating poultry air sac inflammation and preparation method thereof

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