CN105267687A - Traditional Chinese medicine preparation for treating acute tonsillitis and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating acute tonsillitis and preparation method thereof Download PDF

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CN105267687A
CN105267687A CN201510874933.8A CN201510874933A CN105267687A CN 105267687 A CN105267687 A CN 105267687A CN 201510874933 A CN201510874933 A CN 201510874933A CN 105267687 A CN105267687 A CN 105267687A
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rhizoma
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栾绍敏
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Abstract

The invention provides a traditional Chinese medicine preparation for treating acute tonsillitis and a preparation method thereof. The traditional Chinese medicine preparation comprises the following raw medicinal materials: wall spiders' egg-case, Dichondra repens, a disinfectant, manystem stonecrop leaf, semen plantaginis, Indian rorippa herb, Siam psychotria herb, virginia grape fern herb with root, farges decaisnea root, endive, Chinese arundina herb, adder-wort, gynostemma pentaphylla, Involute Spikemoss Herb, bentham dichrocephala herb, Radix Maclurae, Lobedfruit Schizocapsa Rhizome, Chinese ixora flower, Radermachera sinica, welted thistle, root of Shorthairy Antenoron Herb, Meadowrue Root and Rhizome, denseflower bulbophyllum herb, capitate knotweed herb and Canton fairybells root and rhizome. The traditional Chinese medicine preparation for treating acute tonsillitis disclosed by the invention has the beneficial effects that the traditional Chinese medicine preparation is convenient to use and safe and does not have any toxic or side effect, the total effective rate and the cure rate are high, the effectiveness is fast, and the preparation process is simple.

Description

A kind of Chinese medicine preparation for the treatment of acute tonsillitis and preparation method thereof
Technical field
The present invention relates to engineering of traditional Chinese medicine technical field, particularly relate to a kind of Chinese medicine preparation for the treatment of acute tonsillitis and preparation method thereof.
Background technology
Acute tonsillitis is a kind of very common disease of pharynx, is multiplely born in child and person between twenty and fifty, and Main Pathogenic Bacteria is beta hemolytic streptococcus, and staphylococcus, Diplococcus pneumoniae and adenovirus also can cause primary disease.Acute tonsil patient, two cheeks are crimson, mouth frowziness, tongue by thick fur, cervical lymph node, the particularly lymph node at angle of mandible place often enlargement, and have tenderness, leukocyte showed increased.Do not check that can see dissimilar tonsillitis has different manifestations according to office.Acute congestive tonsillitis is also known as acute catarrhal tonsillitis, and main manifestations is that tonsil hyperemia, swelling, surface are without purulent secretion.Acute suppurative tonsillitis containing acute lacunar tonsillitis and acute follicular tonsillitis, shows as tonsil and palatine arches is obviously congested, antiadoncus; Crypts type performance crypts mouth has yellow-white pus point, and exudate can be fused into membranaceous sometimes, does not exceed tonsil scope, is easy to wipe away and does not leave over hemorrhage wound surface; Follicular main manifestations is that the lymph follicle of tonsil essence is congested, and swelling, suppuration, tonsil forms the little protuberance of albumen color.
The traditional Chinese medical science claims acute tonsillitis to be " eroded tonsillitis ", and property is gained the name to nipple like Bombycis mori together.The traditional Chinese medical science thinks that throat is belonging to lung stomach, and be the door of lung stomach, wind-heat evil toxin enters from mouth and nose, invades outside wind heat, Lung Qi obstruction, the wind and heat in the lung meridian circulation criminal of going up, and knot is fallen ill in throat suddenly; Or polyphagia savoury, hot and suffocating fire-transformation taste intrinsic heat, feels wind heat again, and burning hot evil poison is fought joint pharyngeal tonsils, and causes stagnation of QI-blood, hyperactivity of toxic heat, and the rotten sarolemma that burns becomes pus, therefore acute suppurative tonsillitis mostly belongs to anemopyretic or excessiveness of stomach-fire type.Think again the main food of receiving of pharynx simultaneously, under lie in stomach and company's six internal organs; Larynx department breathe, under lie in lung and connect the five internal organs.Lung governing skin and hair, the main flesh natural fibre line of meat of stomach, pharynx, larynx, lung, stomach are always closely linked with the gas in the world, therefore are subject to ailment said due to cold or exposure invasion and attack.Ailment said due to cold or exposure virus, both can direct attack throat, can attack fur outward again, made the flesh natural fibre line of meat inaccessible, not catharsis outward, inside not sensible, and the gas of lung stomach is stopped up and held back, and loses in a surname smooth, strongly fragrant and heat-dissipating, and superinverse throat, for swelling as pain.
Summary of the invention
Technical problem to be solved by this invention is, utilizes the theory of Chinese medical science that China is traditional, provides a kind of effective percentage high and Chinese medicine preparation of the treatment acute tonsillitis that toxic and side effects is little and preparation method thereof.
In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine preparation for the treatment of acute tonsillitis, described Chinese medicine preparation comprises following raw medicinal material: Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae, Herba Psychotriae Siamicae, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., Radix decaisneae fargesii, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herb Gynostemmae Pentaphylli, Herba Selaginellae Involventis, Herba Houttuyniae, Radix Cudraniae, Rhizoma Schizocapsae Plantagineae, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Radix radermacherae sinicae, Herba Cardui Crispi, Radix Antenoronis Filiformis, Radix et Rhizoma Thalictri, Herba Bulbophylli Odoratissim, Herba Polygoni Capitati and Radix et Rhizoma Dispori Cantoniensis.
The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can be preferably: Uroctea compatilis Koch. 15 ~ 25 parts, Herba Dichondrae Repentis 10 ~ 25 parts, disinfectant 15 ~ 30 parts, Herba Sedi Multicaulis 20 ~ 30 parts, Semen Plantaginis 10 ~ 25 parts, Herba Rorippae 15 ~ 30 parts, Herba Psychotriae Siamicae 10 ~ 20 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 15 ~ 25 parts, Radix decaisneae fargesii 20 ~ 30 parts, Herba Sonchi Arvensis 15 ~ 25 parts, Herba Arundinae Chinensis 10 ~ 25 parts, Rhizoma Bistortae 10 ~ 20 parts, Herb Gynostemmae Pentaphylli 20 ~ 35 parts, Herba Selaginellae Involventis 15 ~ 30 parts, Herba Houttuyniae 10 ~ 30 parts, Radix Cudraniae 10 ~ 25 parts, Rhizoma Schizocapsae Plantagineae 15 ~ 25 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 20 ~ 30 parts, Radix radermacherae sinicae 5 ~ 15 parts, Herba Cardui Crispi 10 ~ 25 parts, Radix Antenoronis Filiformis 10 ~ 30 parts, Radix et Rhizoma Thalictri 10 ~ 25 parts, Herba Bulbophylli Odoratissim 20 ~ 35 parts, Herba Polygoni Capitati 10 ~ 20 parts and Radix et Rhizoma Dispori Cantoniensis 15 ~ 25 parts.
The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also more preferably: Uroctea compatilis Koch. 15 ~ 20 parts, Herba Dichondrae Repentis 20 ~ 25 parts, disinfectant 20 ~ 30 parts, Herba Sedi Multicaulis 25 ~ 30 parts, Semen Plantaginis 15 ~ 25 parts, Herba Rorippae 15 ~ 25 parts, Herba Psychotriae Siamicae 15 ~ 20 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 20 ~ 25 parts, Radix decaisneae fargesii 20 ~ 25 parts, Herba Sonchi Arvensis 20 ~ 25 parts, Herba Arundinae Chinensis 15 ~ 20 parts, Rhizoma Bistortae 10 ~ 15 parts, Herb Gynostemmae Pentaphylli 20 ~ 30 parts, Herba Selaginellae Involventis 20 ~ 30 parts, Herba Houttuyniae 15 ~ 25 parts, Radix Cudraniae 10 ~ 20 parts, Rhizoma Schizocapsae Plantagineae 15 ~ 20 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 25 ~ 30 parts, Radix radermacherae sinicae 10 ~ 15 parts, Herba Cardui Crispi 15 ~ 25 parts, Radix Antenoronis Filiformis 20 ~ 30 parts, Radix et Rhizoma Thalictri 15 ~ 25 parts, Herba Bulbophylli Odoratissim 20 ~ 30 parts, Herba Polygoni Capitati 15 ~ 20 parts and Radix et Rhizoma Dispori Cantoniensis 20 ~ 25 parts.
The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation also can more preferably: Uroctea compatilis Koch. 18 parts, Herba Dichondrae Repentis 23 parts, disinfectant 25 parts, Herba Sedi Multicaulis 25 parts, Semen Plantaginis 21 parts, Herba Rorippae 15 parts, Herba Psychotriae Siamicae 19 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 22 parts, Radix decaisneae fargesii 23 parts, Herba Sonchi Arvensis 21 parts, Herba Arundinae Chinensis 17 parts, Rhizoma Bistortae 13 parts, Herb Gynostemmae Pentaphylli 25 parts, Herba Selaginellae Involventis 26 parts, Herba Houttuyniae 20 parts, Radix Cudraniae 15 parts, Rhizoma Schizocapsae Plantagineae 18 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 27 parts, Radix radermacherae sinicae 13 parts, Herba Cardui Crispi 20 parts, Radix Antenoronis Filiformis 25 parts, Radix et Rhizoma Thalictri 20 parts, Herba Bulbophylli Odoratissim 25 parts, Herba Polygoni Capitati 15 parts and Radix et Rhizoma Dispori Cantoniensis 22 parts.
When the dosage form of described Chinese medicine preparation is granule, its preparation method comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 ~ 6 times, mixture is the ethanol of 80% ~ 95%, be heated to boiling reflux 4 ~ 6 hours, filter, take backflow as solvent, take filtering residue as solute, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.08Mpa, relative density is the mastic of 1.05 ~ 1.10, spraying dry, the inlet temperature of spray dryer 160 ~ 175 DEG C, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder,
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes granule, in 40 ~ 50 DEG C of dryings, obtains granule.
When the dosage form of described Chinese medicine preparation is syrup, its preparation method comprises the following steps:
The first step, by Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae and Herba Psychotriae Siamicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,
Second step, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herba Selaginellae Involventis, Herba Houttuyniae and Radix Cudraniae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;
3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;
4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.
Beneficial effect of the present invention: the Chinese medicine preparation that acute tonsillitis of the present invention uses is easy to use, safe without toxic side effect, total effective rate and cure rate high, instant effect, preparation technology is simple.
Detailed description of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of acute tonsillitis, Chinese medicine preparation comprises following raw medicinal material: Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae, Herba Psychotriae Siamicae, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., Radix decaisneae fargesii, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herb Gynostemmae Pentaphylli, Herba Selaginellae Involventis, Herba Houttuyniae, Radix Cudraniae, Rhizoma Schizocapsae Plantagineae, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Radix radermacherae sinicae, Herba Cardui Crispi, Radix Antenoronis Filiformis, Radix et Rhizoma Thalictri, Herba Bulbophylli Odoratissim, Herba Polygoni Capitati and Radix et Rhizoma Dispori Cantoniensis.
The pharmacology of various raw medicinal material is as follows:
Uroctea compatilis Koch.: [another name] wall cocoon, Uroctea compatilis Koch. nest curtain, white, Bi Spider nest, spider nest, Bi Spider Wo, Spider spider nest, happiness youngster nest, Uroctea compatilis Koch. cocoon, gossamer urocteae.[source] medical material Ji Yuan: be nest and the egg capsule of Uroctea compatilis Koch. section animal Uroctea compactilis (L. Koch) and Uroctea lessert.[nature and flavor] salty in the mouth; Bitter; Property is put down.[return through] lung; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Hemostasis; Sore.Main sore throat; Tonsillitis; Toothache; Epistaxis; Traumatic hemorrhage; The open sore part is not held back; Vomiting; Cough.[each discussion] " Suzhou this product medical material ": control sore throat, tonsillitis, congenital deformity of the tongue.[extracts] " China's book on Chinese herbal medicine "
Herba Dichondrae Repentis: [another name] pocket grass, JINSUOSHI, Herba Dichodrae, the big grass of spiral shell, little Hydrocotyle vulgaris L., wineglass nest, Herba Carpesii Divaricati, Herba Kummerowiae Striatae, little Herba Centellae, little grass windward, little bowl bowl grass, little Herba Lobeliae Chinensis.[source] medical material Ji Yuan: be the herb of dicotyledon scammonia section plant Herba Dichodrae.[nature and flavor] toil; Cool.[return through] lung; Liver Channel.[function cures mainly] heat clearing away; Dampness removing; Removing toxic substances.Main jaundice; Dysentery; Sand Stranguria; Nebulousurine; Edema; Furuncle swelling toxin; Traumatic injury; Venom.[extracts] " China's book on Chinese herbal medicine "
Disinfectant: [another name] Viola arcuata, arrow grass, tank mouth dish, little Herba Violae japonicae, Viola grypoceras A. Gray, water-white Viola grypoceras A. Gray, spend Carnis Arca inflata shell grass in vain, band blood Herba Violae japonicae, triumph grass, Bai Laowan, triangle gold brick, Cipangopaludina chinensis teacher, the rotten bean of water.[source] medical material Ji Yuan: be the herb of Violaceae plant common violet.[nature and flavor] mildly bitter flavor; Cool in nature.[function cures mainly] heat-clearing and toxic substances removing; Cough-relieving; Hemostasis.Main cough due to lung-heat; Tonsillitis; Eye conjunctivitis; Furuncle swelling toxin; Agkistrodon halys bites; Knife injury is hemorrhage.[extracts] " China's book on Chinese herbal medicine "
Herba Sedi Multicaulis: [another name] Herba Orostachyos, watt flower, Dian Wahua, Parmelia saxatilis Ach., Shi Gen, Herba Peristrophes, rock are complied with one's wishes.[source] medical material Ji Yuan: be stem and leaf or the root of crassulaceae plants gold stem Herba hylotelephii erythrosticti.[nature and flavor] sweet in the mouth; Micro-pungent; Cold nature.[return through] lung; Kidney; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Cooling blood for hemostasis; Wind-damp dispelling.Main laryngopharynx swelling and pain; Burst soup in oral cavity; Eczema sore; Epistaxis; Hemoptysis; Spitting of blood; Rheumatic arthralgia; Headache due to pathogenic wind-heat.[each discussion] be " the southern regions of the Yunnan Province book on Chinese herbal medicine " 1.: control laryngopharynx swelling and pain, disappear tonsillitis, network anemofrigid-damp arthralgia of passing through, and bones and muscles pain washes the damp and hot poison of skin ulcer.2. " Yunnan Chinese herbal medicine ": heat-clearing and toxic substances removing, hemostasis, blood pressure lowering, wind-damp dispelling.[extracts] " China's book on Chinese herbal medicine "
Semen Plantaginis: [source] this product is the dry mature seed of Plantaginaceae plant Herba Plantaginis or Plantago depressa Willd.[nature and flavor] are sweet, are slightly cold.[return through] returns liver, kidney, lung, small intestine meridian.[function cures mainly] clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm.For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.[extracts] " Chinese Pharmacopoeia "
Herba Rorippae: [another name] peppery rice dish, sarson, pool Pueraria lobota dish, Herba Rorippae, Radix Loxostigmatis griffithii, Carnis Gallus domesticus dish, Tian Gecai, Herba Rorippae, wild potherb mustard, wild mustard grass, wild herbs, barbarea, Du Gencai, chervil, spun gold pod.[source] medical material Ji Yuan: be that thing Herba Rorippae and the herb without lobe Han are planted by ten Zi Hua sections.[nature and flavor] acrid in the mouth; Bitter; Slightly warm in nature.[return through] lung; Liver Channel.[function cures mainly] expelling phlegm for arresting cough; Induce sweat cold expelling; Promoting blood circulation and detoxication; Dampness removing jaundice eliminating.Main cough phlegm dyspnea; Cold, fever; Measles is sent out not smooth thoroughly; Rheumatic arthralgia; Laryngopharynx swelling and pain; Furuncle carbuncle; Dermatitis rhus; Amenorrhea; Traumatic injury; Jaundice; Edema.[each discussion] 1. " Kweiyang medicinal herbs among the people ": heat-clearing and toxic substances removing, relieving cough and resolving phlegm.Dermatitis rhus is controlled in external, furuncle, carbuncle.2. Guangzhou army " conventional Chinese herbal medicine handbook ": clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure cold heating, laryngopharynx swelling and pain, aphonia; Cough due to lung-heat, hemoptysis; Acute rheumatic arthritis; Edema.3. " Fujian Chinese herbal medicine ": dispelling wind expelling pathogenic factors from the exterior, regulating qi-flowing for harmonizing stomach.[extracts] " China's book on Chinese herbal medicine "
Herba Psychotriae Siamicae: [another name] Herba Equiseti Hiemalis, Herba Clinopodii Polycephali, Radix Sophorae Tonkinensis grass, synthetism Herba pteridii latiusculi, horse Radix Ginseng, a tower grass, nib grass, tower careless, hair cylinder grass, rich knotweed.[source] medical material Ji Yuan: for Herba Equiseti Hiemalis produces the herb of plant Radix Scorzonerae Albicaulis.[nature and flavor] are bitter; Cool; Sweet.[return through] lung; Liver; Spleen; Large intestine channel.[function cures mainly] improving eyesight; Heat clearing away; Dampness removing; Hemostasis.The red distending pain of argument; Pterygium; Gonorrhea; Icterohepatitis; Hematuria; Metrorrhagia.[each discussion] 1. " register planted by Guangxi medicine ": root: hemostasis, cough-relieving, controls traumatic injury.Leaf: detumescence, wind dispelling.2. " choosing of Yunnan Chinese herbal medicine ": heat-clearing and toxic substances removing, pain relieving.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "
Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw.: [another name] YIDUOYUN, Jue Qi.[source] medical material Ji Yuan: be root or the herb of Botrychiaceae plant Herba pteridii latiusculi beanstalk.[nature and flavor] are bitter; Puckery; Cool; Sweet; Be slightly cold.[return through] lung; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Suppressing the hyperactive liver eliminating stagnation; Expelling wind for relieving convulsion.Main lung abscess; Venom; Conjunctival congestion; Scrofula; Cough; Serpentis poison; Acute infantile convulsion wind; Rheumatic arthralgia; Traumatic injury.[each discussion] 1. " Shaanxi Chinese herbal medicine ": heat-clearing and toxic substances removing, suppressing the hyperactive liver eliminating stagnation.Control lung abscess, conjunctivitis, impairment caused by overstrain, venom, scrofula.2. Nanchuan " conventional Chinese herbal medicine handbook ": tonify deficiency lung moistening, relieving cough and resolving phlegm.Control cough, weak and celostomia after being ill.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "
Radix decaisneae fargesii: [another name] cat melon, Intestinum Gallus domesticus, cat dung melon, cat dung maple, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp..[source] medical material Ji Yuan: be root or the stem of plants of Lardizabalaceae Radix decaisneae fargesii.[nature and flavor] Gan Xin; Pungent; Property is put down.[return through] returns lung; Liver Channel.[function cures mainly] expelling wind and removing dampness; Clearing away lung-heat to relieve cough.Main air pain of dampness syndrome; Anus wets rotten; Pudendal pruritus; Pulmonary tuberculosis cough.[each discussion] 1. " Guizhou medical herbs ": clearing away lung-heat to relieve cough, evil-wind expelling and dampness removing.2. " Shaanxi Chinese herbal medicine ": root and fruit heat-clearing and toxic substances removing.[extracts] " China's book on Chinese herbal medicine "
Herba Sonchi Arvensis: [another name] Mai dish, wild Herba Sonchi Oleracei, wild gutweed, bitter Pueraria montana (Lour.) Merr., Herba Ixeritis Denticulatae, gets numb dish, lettuce dish, bent numb dish, bitter maror, Herba Patriniae.[source] medical material Ji Yuan: for feverfew is crawled the herb of stem Herba Sonchi Oleracei.[nature and flavor] bitter in the mouth; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Promoting diuresis and pus discharge; Cooling blood for hemostasis.Main laryngopharynx swelling and pain; Furuncle toxic swelling; Hemorrhoid; Acute bacillary dysentery; Intestinal is scorching; Lung abscess; Acute appendicitis; Leaf blood; Epistaxis ' spitting of blood; Hematuria; Have blood in stool; Metrorrhagia.[each discussion] 1. " Hebei Chinese medicine handbook ": heat-clearing and toxic substances removing.Control acute bacillary dysentery, acute laryngitis, internal hemorrhoid is deviate from.2. " the common identification obscuring Chinese herbal medicine ": control leucorrhea and postnatal blood stasis stomachache, appendicitis.[extracts] " China's book on Chinese herbal medicine "
Herba Arundinae Chinensis: [another name] great Ye Radix Cynanchi Paniculati, careless Rhizoma Zingiberis Recens, mountain Corm Eleocharitis.[source] medical material Ji Yuan: be herb and the root stock of orchid Herba Murdanniae Divergentis.[nature and flavor] are bitter; Be slightly cold.[return through] liver; Kidney; Urinary bladder channel.[function cures mainly] heat-clearing and toxic substances removing; Expelling wind and removing dampness.Main pyretic stranguria; Jaundice; Edema; Beriberi edema; Hernia is suffered from abdominal pain; Rheumatic arthralgia; Venom; Sore and toxic; Traumatic injury.[each discussion] be " choosing of Simao, Yunnan Chinese herbal medicine " 1.: heat-clearing and toxic substances removing, wind-damp dispelling, antiinflammatory, diuresis.Treating rheumatic lumbago and skelalgia, stomachache, urinary tract infection, beriberi edema, alimentary toxicosis.[extracts] " China's book on Chinese herbal medicine "
Rhizoma Bistortae: [another name] Herba Salviae Chinensis, Rhizoma Paridis, cutter cut medicine, copper sieve, shrimp ginseng, shrimp, mountain shrimp.[source] this product is the dry rhizome of polygonaceae plant Rhizoma Bistortae.[nature and flavor] are bitter, puckery, are slightly cold.[return through] returns lung, liver, large intestine channel.[function cures mainly] heat-clearing and toxic substances removing, detumescence, hemostasis.For bloody dysentery, diarrhea of heat type, cough due to lung-heat, carbuncle, scrofula, aphtha of the mouth and tongue, spits blood, epistaxis, bleeding hemorrhoids, venom.[extracts] " Chinese Pharmacopoeia "
Herb Gynostemmae Pentaphylli: [another name] Herba Gynostemmatis, Herba Gynostemmatis, Herb Gynostemmae Pentaphylli, raw, the Herba Gynostemmatis that lands.[source] medical material Ji Yuan: be the herb of cucurbitaceous plant Herb Gynostemmae Pentaphylli.[nature and flavor] bitter in the mouth; Micro-sweet; Cool in nature.[return through] returns lung; Spleen; Kidney channel.[function cures mainly] heat clearing away; Tonify deficiency; Removing toxic substances.Main body void is weak; Nephrasthenia emission; Leukopenia; Hyperlipemia; Viral hepatitis; Chronic gastroenteritis; Chronic tracheitis.[extracts] " China's book on Chinese herbal medicine "
Herba Selaginellae Involventis: [another name] Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), Herba Selaginellae Involventis, golden almond, Shi Yangcao, Rana nigromaculata pawl, flower lung gold.[source] medical material Ji Yuan: be the herb of Spikemoss plant Herba Selaginellae Involventis.[nature and flavor] light, micro-hardship, cool.[return through] lung; Liver; The heart; Spleen channel.[function cures mainly] clearing away heat-damp and promoting diuresis; Cough-relieving; Hemostasis; Removing toxic substances.Main jaundice due to damp-heat; Dysentery; Edema; Ascites; Stranguria; Productive cough due to phlegm-damp; Spitting of blood; Spit blood; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Acute mastitis; Scrofula; Hemorrhoid; Scald.[each discussion] 1. " Fujian traditional herbal medicine ": can flexibilizing tendon and strengthening bone, and QI invigorating improving eyesight, removing heat from the liver, treats jaundice.2. " Luchuan book on Chinese herbal medicine ": cooling blood for hemostasis, inducing diuresis to remove edema.Control proctoptosis hematochezia, edema.3. " Traditional Chinese Medicine in Sichuan will ": heat-clearing and toxic substances removing.Control haematemesis, bleeding hemorrhoids, gonorrhea, burn and injury by sword or axe hemorrhage.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "
Herba Houttuyniae: [another name] three rosetangle, constellation grass, Fructus Piperis, drum fourth grass, the sub-grass of nebula, Herba Asari, little trowel head grass, bright head careless.[source] medical material Ji Yuan: be the herb of the little Herba Houttuyniae of feverfew and chrysanthemum leaf Herba Houttuyniae.[nature and flavor] bitter in the mouth; Cold in nature.[function cures mainly] heat-clearing and toxic substances removing; Dispelling pathogenic wind for improving eyesight.Main pneumonia; Hepatitis; Dysentery; Dyspepsia; Malaria; Nyctalopia; Leukorrhagia; Skin infection.[each discussion] " choosing of Yunnan Chinese herbal medicine ": heat-clearing and toxic substances removing, pain relieving, antidiarrheal.Cure cold high heat, diarrhoea, hepatitis.[extracts] " China's book on Chinese herbal medicine "
Radix Cudraniae: [another name] three-bristle cudrania root, river break stone, cotton root, draw cattle to enter stone, three-bristle cudrania rattan root, yellow Serpentis, the yellow dustpan in mountain, ferrum hedge root, HUANGLONG decortication, thorn paper mulberry, kuling supplejack root, the wild Radix Astragali, Semen Sterculiae Nobilis, thousand layers of skin.[source] medical material Ji Yuan: be the root of moraceae plants cudrania cochinchinensis or Zhe Shu.[nature and flavor] are lightly seasoned; Micro-hardship; Cool in nature.[function cures mainly] dispelling wind and removing obstruction in the collateral; Removing damp-heat; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Traumatic injury; Yellow cellulitis; Parotitis; Pulmonary tuberculosis; Gastric duodenal ulcer; Stranguria with turbid discharge; Distention of the abdomen caused by various parasites; Amenorrhea; Impairment caused by overstrain hemoptysis; Treatment carbuncle sore swells.[each discussion] be Guangzhou army " conventional Chinese herbal medicine handbook " 1.: cool the blood dissipate blood stasis.Control amenorrhea.2. " the practical Chinese herbal medicine in Guangxi newly selects ": heat clearing and blood circulation promoting, eliminating phlegm and stopping cough.Control impairment caused by overstrain hemoptysis.3. " choosing of Yunnan Chinese herbal medicine ": anti-inflammatory analgetic.Control mumps, furuncle and phyma.[extracts] " China's book on Chinese herbal medicine "
Rhizoma Schizocapsae Plantagineae: [source] medical material base source: is the tuber of Rhizoma amorphophalli potato section plant dehiscent fruit potato.[nature and flavor] are sweet; Bitter; Cool.[function cures mainly] heat-clearing and toxic substances removing; Eliminating phlegm and stopping cough; Regulate the flow of vital energy and stop production capacity; Dissipating blood stasis stops blooding.Main cold, fever; Phlegm-heat cough; Pertussis; Abdominal distention; Dysentery is suffered from abdominal pain; Dyspepsia; Infantile malnutrition; Hepatitis; Laryngopharynx swelling and pain; Toothache; Mumps; Scrofula; Skin ulcer swells; Scald, burn; Herpes zoster; Traumatic injury; Traumatic hemorrhage.[each discussion] 1. " Nanning City's medicine is forgotten ": antiinflammatory, removing toxic substances, pain relieving.Control peratodynia, acid regurgitation, cough, Hakuri, pharyngalgia, carbuncle skin ulcer is controlled in external application.2. " choosing of Simao, Yunnan Chinese herbal medicine ": heat-clearing and toxic substances removing, anti-inflammatory analgetic.Control gastric and duodenal ulcers, hypertension, hepatitis, stomachache, scald, burn, skin infection.3. " the practical Chinese herbal medicine in Guangxi newly selects ": cooling blood and relieving pain, dissipating blood stasis for subsidence of swelling.Control Peptic Ulcers, infantile malnutrition, stomachache, traumatic injury, carbuncle, innominate toxic swelling, gastric heat pain, acute gastroenteritis, toothache.[extracts] " China's book on Chinese herbal medicine "
Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati): [another name] Ixora stricta, red silk ball, Bulbus lilii concoloris, May Flower, buy son wood, Rhododendron simsii Planch., Niu Lan, pearl paulownia, kind Caulis et folium euphorbiae milii, Flos Ixorae Chinensis, Brassaiopsis glomerulata (Bl.) Regel wood, red oriental cherry, Folium Lantanae Camarae, Lagerstroemia indica L., the elixir of life are colored.[source] medical material Ji Yuan: be the flower of dicotyledon medicine Maguireothamnus speciosus Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati).[nature and flavor] are sweet light; Cool.[return through] Liver Channel.[function cures mainly] clearing away heat and cooling blood; Eliminating stasis to stop pain.Main hypertension; Menoxenia; Amenorrhea; Traumatic injury; Skin infection furuncle and phyma.[each discussion] be " the SHENGCAO property of medicine is standby to be wanted " 1.: disappear skin ulcer, and pus of tut-tuting, dispels the wind, pain relieving, reason phlegm-fire.2. " Guangxi Chinese medicinal herbal ": dissipating blood stasis, continuous muscle, synthetism, pain relieving.Control injured.3. Guangzhou army " conventional Chinese herbal medicine handbook ": removing heat from the liver to lower the high blood pressure, promoting blood circulation to remove blood stasis.[extracts] " China's book on Chinese herbal medicine "
Radix radermacherae sinicae: [source] medical material Ji Yuan: be the root of Bignoniaceae plant Radix radermacherae sinicae, leaf or fruit.[nature and flavor] bitter in the mouth; Cold in nature.[function cures mainly] summer heat clearing toxin resolving; Dissipating blood stasis for subsidence of swelling.Main Sunstroke heating; Carbuncle; Injury and bone fracture; Venom.[each discussion] 1. " Guangxi Chinese herbal medicine ": dissipating blood stasis for subsidence of swelling, heat-clearing and toxic substances removing.2. Guangzhou air force " conventional Chinese herbal medicine handbook ": cool the blood dissipate blood stasis, reducing swelling and alleviating pain.Zhi Gaore has a headache, stomachache, bruise, fracture, carbuncle furuncle, venom.[extracts] " China's book on Chinese herbal medicine "
Herba Cardui Crispi: [source] medical material Ji Yuan: be feverfew silk hair Herba Cardui Crispi and the herb or the root that save hair Herba Cardui Crispi.[nature and flavor] mildly bitter flavor; Cool in nature.[function cures mainly] dispels the wind; Heat clearing away; Dampness removing; Cooling blood for hemostasis; Promoting blood circulation and detumescence.Main cold cough; Have a headache dizzy; Urinary system infection; Chyluria; Leucorrhea; Jaundice; Rheumatic arthralgia; Spit blood; Epistaxis; Hematuria; Menorrhagia; Dysfunctional uterine hemorrhage; Traumatic injury; Furuncle furuncle and phyma; Swelling and pain of hemorrhoid; Burn.[each discussion] 1. " Chinese herbal medicine is commonly used in Tibet ": removing heat from blood, hemostasis, dissipating blood stasis for subsidence of swelling.Control various hemorrhage, traumatic injury congestive edema, malignant boil, burn, scald.2. Soviet Union doctor " Chinese herbal medicine handbook ": dispel the wind, dampness removing, heat clearing away, detumescence.Control chyluria, hematuria, urinary tract infection, influenza, leukorrhagia, menorrhagia; External curing pyogenic infections from tumour or sore, swelling and pain of hemorrhoid.[extracts] " China's book on Chinese herbal medicine "
Radix Antenoronis Filiformis: [another name] extra large root, ferrum corner angle Radix Notoginseng, Cortex cynoglossi zeylanici radicis, Herba Lycianthis Biflorae, waterline flower root, knotweed seven, Herba Senecionis Chrysanthemoidis, shorthairy antenoron root.[source] medical material Ji Yuan: be the rhizome of few section plant Herba Antenoronis Neofiliformis (Herba Antenoronis Filiformis) and undercoat Herba Antenoronis Neofiliformis (Herba Antenoronis Filiformis).[nature and flavor] are bitter; Pungent; Cold nature.[function cures mainly] cooling blood for hemostasis; Eliminating stasis to stop pain; Heat-clearing and toxic substances removing.Main cough spitting of blood; Spit blood; Metrorrhagia; Menoxenia; Dysmenorrhea; Epigastric pain; Have loose bowels; Dysentery; Traumatic injury; Rheumatic arthralgia; Scrofula; Swollen ulcer drug; Burn and scald; Biting of poison.[each discussion] 1. supplement to the Herbal: main cholera attacked by pestiferous factors, cardiac and abdominal pain, sore throat, diseases due to noxious agents produced by various parasites, carbuncle is disliked swollen, and red white trip gizzard, Serpentis stings dog poison.Wine and water mill clothes, that applies is also good.2. " Chinese herbal medicine is commonly used in Sichuan ": dissipating blood stasis circulation of qi promoting, reducing swelling and alleviating pain.Control traumatic injury, consumptive disease wound is spitted blood.3. Jiangxi " medical herbs handbook ": dissipating blood stasis stops blooding, removing toxic substances promoting the circulation of QI.[extracts] " China's book on Chinese herbal medicine "
Radix et Rhizoma Thalictri: [another name] Radix et Rhizoma Thalictri.[source] medical material Ji Yuan: be the root and rhizome of ranunculaceae plant spun gold Radix et Rhizoma Thalictri, Zhaotong Thalictrum aquilegifolium L. var. sibiricum Regel, plateau Thalictrum aquilegifolium L. var. sibiricum Regel, leafy Thalictrum aquilegifolium L. var. sibiricum Regel, baikal meadowrue root, long column baikal meadowrue root, yellow Thalictrum aquilegifolium L. var. sibiricum Regel, sticky Thalictrum aquilegifolium L. var. sibiricum Regel etc.[nature and flavor] bitter in the mouth; Cold in nature.[return through] GUIXIN; Liver; Large intestine channel.[function cures mainly] heat clearing and damp drying; Eliminating fire and detoxication.Cure mainly damp-heat dysentery; Jaundice; Sore swollen toxin; Conjunctival congestion and swelling pain; Cold, fever; Cancerous protuberance.[each discussion] " Chinese herbal medicine is commonly used in Tibet ": heat-clearing and toxic substances removing, dispel the wind removing heat from blood, anti-inflammtory anti-dysentery.Control conjunctivitis, infectious hepatitis, carbuncle furuncle, dysentery.Leaf, flower curing arthritis.[extracts] " China's book on Chinese herbal medicine "
Herba Bulbophylli Odoratissim: [another name] little Herba Bulbophylli Odoratissim, Bulbophyllum calodictyon schlecht., extremely fragrant Bulbophyllum, elaeagnus conferta fruits.[source] medical material Ji Yuan: be the herb of orchid Bulbophyllum odoratissimum Lindl..[nature and flavor] are sweet; Light; Cool.[return through] lung; Liver; Kidney channel.[function cures mainly] moistening the lung and resolving phlegm; Removing obstruction in the collateral to relieve pain.Main hemoptysis of pulmonary tuberculosis; Chronic tracheitis; Chronic pharyngitis; Hernia pain; Menoxenia; Rheumatic arthralgia; Traumatic injury.[each discussion] be " Kunming conventional medical herbs among the people " 1.: wind-damp dispelling, active, circulation of qi promoting, pain relieving.2. " choosing of Yunnan Chinese herbal medicine ": synthetism antiinflammatory, moistening the lung and resolving phlegm.Control fracture, pulmonary tuberculosis, spitting of blood, chronic tracheitis, pneumonia convalescent period, chronic pharyngitis, menoxenia.3. " catalogue planted by Guizhou medicine ": clearing heat and moistening dryness, promoting the production of body fluid to quench thirst.[extracts] " China's book on Chinese herbal medicine "
Herba Polygoni Capitati: [source] medical material Ji Yuan: be the herb of polygonaceae plant Herba Polygoni Capitati.[nature and flavor] are bitter; Pungent; Cool in nature.[function cures mainly] clearing away heat-damp and promoting diuresis; Promoting blood circulation and stopping pain.Main dysentery; Pyelonephritis; Cystitis; Lithangiuria; Rheumatalgia; Traumatic injury; Mumps; Skin infection; Eczema.[each discussion] 1. " Guangxi Chinese medicinal herbal ": wind-damp dispelling, eliminating stasis to stop pain.Dispelling the wind and dampness pathogens, traumatic injury.2. " Guangxi Chinese herbal medicine ": detoxicating, relieving inflammation.Control dysentery, skin ulcer, innominate toxic swelling.[extracts] " China's book on Chinese herbal medicine "
Radix et Rhizoma Dispori Cantoniensis: [source] medical material Ji Yuan: be the root and rhizome of liliaceous plant cantonese fairy bells.[nature and flavor] bitter in the mouth; Pungent; Cool in nature.[function cures mainly] wind-damp dispelling; Relaxing muscles and tendons to promote blood circulation; Heat clearing away expelling phlegm for arresting cough.Main air arthralgia chiefly caused by damp pathogen is demonstrate,proved; Joint lumbago and skelalgia; Traumatic injury; Fracture; Asthenia; Osteopyrexia and fever; Pulmonary tuberculosis is spat blood; Cough due to lung-heat; Burn and scald.[each discussion] 1. " Shaanxi Chinese herbal medicine ": YIN nourishing tonify deficiency, wind-damp dispelling, activating collaterals to relieve pain.Control asthenia, osteopyrexia and fever, pulmonary tuberculosis, palpitation and short breath, lumbago, skelalgia of rheumatism, sciatica.2. " Yunnan Chinese herbal medicine ": synthetism is stopped blooding, anti-inflammatory analgetic, expelling wind and removing dampness.3. " Jiangxi medical herbs ": wind and heat eliminating, relaxing muscles and tendons to promote blood circulation.[extracts] " China's book on Chinese herbal medicine "
The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can more preferably: Uroctea compatilis Koch. 15 ~ 25 parts, Herba Dichondrae Repentis 10 ~ 25 parts, disinfectant 15 ~ 30 parts, Herba Sedi Multicaulis 20 ~ 30 parts, Semen Plantaginis 10 ~ 25 parts, Herba Rorippae 15 ~ 30 parts, Herba Psychotriae Siamicae 10 ~ 20 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 15 ~ 25 parts, Radix decaisneae fargesii 20 ~ 30 parts, Herba Sonchi Arvensis 15 ~ 25 parts, Herba Arundinae Chinensis 10 ~ 25 parts, Rhizoma Bistortae 10 ~ 20 parts, Herb Gynostemmae Pentaphylli 20 ~ 35 parts, Herba Selaginellae Involventis 15 ~ 30 parts, Herba Houttuyniae 10 ~ 30 parts, Radix Cudraniae 10 ~ 25 parts, Rhizoma Schizocapsae Plantagineae 15 ~ 25 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 20 ~ 30 parts, Radix radermacherae sinicae 5 ~ 15 parts, Herba Cardui Crispi 10 ~ 25 parts, Radix Antenoronis Filiformis 10 ~ 30 parts, Radix et Rhizoma Thalictri 10 ~ 25 parts, Herba Bulbophylli Odoratissim 20 ~ 35 parts, Herba Polygoni Capitati 10 ~ 20 parts and Radix et Rhizoma Dispori Cantoniensis 15 ~ 25 parts.
The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation can also more preferably: Uroctea compatilis Koch. 15 ~ 20 parts, Herba Dichondrae Repentis 20 ~ 25 parts, disinfectant 20 ~ 30 parts, Herba Sedi Multicaulis 25 ~ 30 parts, Semen Plantaginis 15 ~ 25 parts, Herba Rorippae 15 ~ 25 parts, Herba Psychotriae Siamicae 15 ~ 20 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 20 ~ 25 parts, Radix decaisneae fargesii 20 ~ 25 parts, Herba Sonchi Arvensis 20 ~ 25 parts, Herba Arundinae Chinensis 15 ~ 20 parts, Rhizoma Bistortae 10 ~ 15 parts, Herb Gynostemmae Pentaphylli 20 ~ 30 parts, Herba Selaginellae Involventis 20 ~ 30 parts, Herba Houttuyniae 15 ~ 25 parts, Radix Cudraniae 10 ~ 20 parts, Rhizoma Schizocapsae Plantagineae 15 ~ 20 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 25 ~ 30 parts, Radix radermacherae sinicae 10 ~ 15 parts, Herba Cardui Crispi 15 ~ 25 parts, Radix Antenoronis Filiformis 20 ~ 30 parts, Radix et Rhizoma Thalictri 15 ~ 25 parts, Herba Bulbophylli Odoratissim 20 ~ 30 parts, Herba Polygoni Capitati 15 ~ 20 parts and Radix et Rhizoma Dispori Cantoniensis 20 ~ 25 parts.
The ratio of weight and number of the various raw medicinal materials in described Chinese medicine preparation also can more preferably: Uroctea compatilis Koch. 18 parts, Herba Dichondrae Repentis 23 parts, disinfectant 25 parts, Herba Sedi Multicaulis 25 parts, Semen Plantaginis 21 parts, Herba Rorippae 15 parts, Herba Psychotriae Siamicae 19 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 22 parts, Radix decaisneae fargesii 23 parts, Herba Sonchi Arvensis 21 parts, Herba Arundinae Chinensis 17 parts, Rhizoma Bistortae 13 parts, Herb Gynostemmae Pentaphylli 25 parts, Herba Selaginellae Involventis 26 parts, Herba Houttuyniae 20 parts, Radix Cudraniae 15 parts, Rhizoma Schizocapsae Plantagineae 18 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 27 parts, Radix radermacherae sinicae 13 parts, Herba Cardui Crispi 20 parts, Radix Antenoronis Filiformis 25 parts, Radix et Rhizoma Thalictri 20 parts, Herba Bulbophylli Odoratissim 25 parts, Herba Polygoni Capitati 15 parts and Radix et Rhizoma Dispori Cantoniensis 22 parts.
When the dosage form of described Chinese medicine preparation is granule, it comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 ~ 6 times, mixture is the ethanol of 80% ~ 95%, be heated to boiling reflux 4 ~ 6 hours, filter, take backflow as solvent, take filtering residue as solute, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.08Mpa, relative density is the mastic of 1.05 ~ 1.10, spraying dry, the inlet temperature of spray dryer 160 ~ 175 DEG C, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder,
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes granule, in 40 ~ 50 DEG C of dryings, obtains granule.、
When the dosage form of described Chinese medicine preparation is syrup, it comprises the following steps:
The first step, by Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae and Herba Psychotriae Siamicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,
Second step, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herba Selaginellae Involventis, Herba Houttuyniae and Radix Cudraniae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;
3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;
4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1: granule prepared by the present invention
Get Uroctea compatilis Koch. 180g, Herba Dichondrae Repentis 230g, disinfectant 250g, Herba Sedi Multicaulis 250g, Semen Plantaginis 210g, Herba Rorippae 150g, Herba Psychotriae Siamicae 190g, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 220g, Radix decaisneae fargesii 230g, Herba Sonchi Arvensis 210g, Herba Arundinae Chinensis 170g, Rhizoma Bistortae 130g, Herb Gynostemmae Pentaphylli 250g, Herba Selaginellae Involventis 260g, Herba Houttuyniae 200g, Radix Cudraniae 150g, Rhizoma Schizocapsae Plantagineae 180g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 270g, Radix radermacherae sinicae 130g, Herba Cardui Crispi 200g, Radix Antenoronis Filiformis 250g, Radix et Rhizoma Thalictri 200g, Herba Bulbophylli Odoratissim 250g, Herba Polygoni Capitati 150g and Radix et Rhizoma Dispori Cantoniensis 220g.
Its preparation method comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 times, mixture is the ethanol of 85%, be heated to boiling reflux 5 hours, filter, take backflow as solvent, take filtering residue as solute, adopt percolation with the speed of 2ml per minute slowly percolation, collect percolate, when being evaporated to 55 DEG C subsequently under vacuum 0.08Mpa, relative density is the mastic of 1.06, spraying dry, the inlet temperature 165 DEG C of spray dryer, leaving air temp 85 DEG C, be ground into powder subsequently, make dried cream powder;
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.3 times and 0.2 times in the dried cream powder obtained, makes granule, in 55 DEG C of dryings, obtains granule.
Embodiment 2: syrup prepared by the present invention
Get Uroctea compatilis Koch. 160g, Herba Dichondrae Repentis 250g, disinfectant 220g, Herba Sedi Multicaulis 280g, Semen Plantaginis 170g, Herba Rorippae 230g, Herba Psychotriae Siamicae 170g, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 230g, Radix decaisneae fargesii 210g, Herba Sonchi Arvensis 240g, Herba Arundinae Chinensis 160g, Rhizoma Bistortae 150g, Herb Gynostemmae Pentaphylli 280g, Herba Selaginellae Involventis 230g, Herba Houttuyniae 160g, Radix Cudraniae 170g, Rhizoma Schizocapsae Plantagineae 150g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 290g, Radix radermacherae sinicae 110g, Herba Cardui Crispi 230g, Radix Antenoronis Filiformis 250g, Radix et Rhizoma Thalictri 230g, Herba Bulbophylli Odoratissim 220g, Herba Polygoni Capitati 180g and Radix et Rhizoma Dispori Cantoniensis 240g.
Its preparation method comprises the following steps:
The first step, Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae and Herba Psychotriae Siamicae are mixed in described ratio, adding relative to the determining alcohol of 6 times, mixture is the ethanol of 85%, heating and refluxing extraction 3 times, each reflux, extract, 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 65 DEG C 60 DEG C, relative density is the medicinal liquid of 1.06, by dry with spray dryer for the concentrated solution after concentrated, be ground into 150 orders subsequently, obtain dry powder;
Second step, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herba Selaginellae Involventis, Herba Houttuyniae and Radix Cudraniae being mixed in described ratio, be ground into powder, is that the ethanol of 85% is as solvent with determining alcohol, flood 60 hours, adopt percolation with the speed of 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.26, dry with spray dryer, be ground into 150 orders subsequently, obtain dry powder, the quality of the ethanol added is 4 times of second step mixture quality;
3rd step, mixes surplus stock medical material in described ratio, add relative to mixture 5 times amount determining alcohol be 75% alcohol reflux 3 times, each 2 hours, filter, filtrate merges, and reclaims ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20, in 65 DEG C of reduced vacuum dryings, obtains dry powder;
4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 4 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 50%, ethyl hydroxybenzoate 0.03%.
Toxicity test:
Acute toxicity testing: application mice 60, male and female half and half, body weight 25-35g, carries out acute toxicity test.Mice is divided into two groups at random, i.e. matched group and administration group, before experiment, fasting 12 hours, is dissolved in water by Chinese medicine granules prepared by embodiments of the invention 1, (concentration is 8.39g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg (namely unit dosage form is 41.95 crude drugs/kg), and matched group gives normal saline, administration in one day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage granule LD50>41.95 crude drug/kg of the present invention, every day, maximum dosage-feeding was 83.9 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention be 8.26g crude drug/day/people, adult body weight in 60KG, average dosage is 0.1377g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 35g) oral administration gavage Chinese medicine of the present invention is 609 times of quantity.Therefore Chinese medicine acute toxicity of the present invention is extremely low, clinical drug safety.
Long term toxicity test: Chinese medicine embodiment 1 granule of the present invention to three groups of mices (often organize 20) by 13.25,25.36 and 42.43g crude drug/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Clinical data:
Case selection: all cases all derive from this Out-patient Department and inpatient, totally 120 examples, be divided into treatment group and each 60 examples of matched group at random.Man 34 example in treatment group, female 26 example; Age 18-63 year; Course of disease 1-5 days; Tonsil I ° of enlargement 34 example, tonsil II ° of enlargement 18 example, tonsil III ° of enlargement 8 example.Man 33 example in matched group, female 27 example; Age 19-65 year; Course of disease 1-5 days; Tonsil I ° of enlargement 35 example, tonsil II ° of enlargement 18 example, tonsil III ° of enlargement 7 example.All patients all meet the diagnostic criteria of acute tonsillitis.Treatment group and matched group no significant difference in sex, age, the course of disease and clinical symptoms, two groups of data comparing difference not statistically significants (P > 0.05), have comparability.
Diagnostic criteria:
Western medicine diagnose standard: 1, General Symptoms: onset is comparatively anxious, can have the diseases such as heating, aversion to cold, weak, cough; 2, local symptom: pharyngalgia is cardinal symptom; 3, sign: the congested enlargement of tonsil, surface or have little pus point, pharyngeal mucous membrane is congested, and angle of mandible can have lymphadenectasis tenderness.
Antiadoncus calibration standard: clinically amygdaline profile size is divided into I ~ III degree.I degree of antiadoncus exceeds palatoglossal arch, but is no more than pharyngopalatine arch; II degree of antiadoncus exceedes pharyngopalatine arch, but does not reach pharynx rear wall center line; III degree of antiadoncus reaches pharynx rear wall center line or exceedes pharynx rear wall center line.
Tcm diagnosis standard: with reference to " disease of tcm Standardization of diagnosis and curative effect ".The diagnosis basis of tonsillitis: with pharyngalgia, dysphagia for cardinal symptom.Acute tonsillitis has heating, and chronic nippled moth does not generate heat or has low grade fever.Acute tonsillitis onset is comparatively anxious, and the course of disease is shorter; Recurrent exerbation is then converted into chronic nippled moth, and the course of disease is longer.Pharyngeal inspection: acute tonsillitis: tonsil hyperemia has pus point in scarlet or peony, enlargement, surface, and severe patient has microabscess; Chronic nippled moth: antiadoncus, hyperemia are kermesinus, or not congested, and there is pus point on surface, or have a little pus to overflow after extruding.Acute tonsillitis and part chronic nippled moth patient blood leukocytes sum and neutrophilic granulocyte increase.Should note differentiating mutually with scarlet fever (scarlet fever), peritonsillar abscess.The syndrome-classification of tonsillitis: invade outside wind heat: acute tonsillitis from the beginning of, pharyngalgia, slight dysphagia.Occur together heat, aversion to cold, cough, the disease such as to cough up phlegm.Pharyngeal mucous membrane and tonsil hyperemia, do not become pus.Thin white fur of tongue, floating and rapid pulse.Excessiveness of stomach-fire: pharyngalgia more very, dysphagia.Fever of the body, thirsty, constipation.The congested redness of pharyngeal and tonsil, above has pus point or microabscess.Red tongue, yellow fur, slippery and rapid pulse.YIN-deficiency of the lung and kidney: pharyngeal drying, scorching hot, hypodynia is uncomfortable.The few expectorant of dry cough, feverish sensation in the palms and soles, metal fatigue, or afternoon low grade fever, the flushing in zygomatic region.Tonsil is dark red, enlargement, or has a little pus to invest surface.Red tongue, thin fur, thready and rapid pulse.Deficiency-weakness of spleen-QI: pharyngeal discomfort, micro-ly to itch or dry, or has foreign body sensation, and color of coughing up phlegm is white, and lustreless complexion, sound is low timid, spiritlessness and weakness, lack of appetite, loose stool.Antiadoncus, hyperemia gentlier or not congested, has a little pus during extruding.Pale tongue is fat, white and moist fur, thready and weak pulse.
Therapeutic Method:
Treatment group: oral Chinese medicine embodiment 1 granule of the present invention, each 15g, every day 3 times.5 days courses for the treatment of.
Matched group: 0.9% sodium chloride injection 150ml, penicillin 8,000,000 u, intravenous drip, every day 1 time.If penicillin anaphylaxis person uses 5% glucose injection 250ml, Azithromycin injection 0.5g instead, intravenous drip, every day 1 time.5 days courses for the treatment of.
Criterion of therapeutical effect: cure: when swallowing, pharyngeal dry pain disappears, and pharyngeal congestion, edema, palatine tonsil enlargement, point-like or lamellar secretions disappear.Take a turn for the better: when swallowing, pharyngeal dry pain obviously alleviates, and pharyngeal congestion, edema, palatine tonsil enlargement, point-like or lamellar secretions disappear substantially.Invalid: symptom and sign are not improved or increase the weight of.
Therapeutic outcome: two groups treat 1 course for the treatment of respectively after, statistical result is see table 1 and table 2.
Table 1 liang group treats Clinical efficacy comparison (unit: example) after 1 course for the treatment of respectively
Group Number of cases Cure Take a turn for the better Invalid Total effective rate
Treatment group 60 46 12 2 58(96.67%)
Matched group 60 31 14 15 45(75.00%)
As can be seen from Table 1, adopt treatment by Chinese herbs acute tonsillitis of the present invention, relative to matched group on therapeutic effect, there is significant improvement short.
After a table 2 liang group treats 1 course for the treatment of respectively, healing number and time compare (unit: example)
Group Number of cases Medication 3 days Medication 4 days Medication 5 days
Treatment group 46 28(46.7%) 38(63.3%) 46(76.7%)
Matched group 31 17(28.3%) 23(38.3%) 31(51.7%)
As can be seen from Table 2, adopt treatment by Chinese herbs acute tonsillitis of the present invention, relative to matched group, not only better efficacy, takes effect also faster.
According to the clinical statistics in above table and toxicity test, Chinese medicine provided by the invention has that total effective rate is high, cure rate is high, the advantage of rapid-action, safe without toxic side effect; Follow up a case by regular visits to 3 months respectively to 31 of 46 and the matched group healing that treatment group is cured, result is added up, and treatment group is without recurrence, and relapse rate is 0% simultaneously; Matched group, recurs 3 people, relapse rate 9.67%.
Concrete case: patient, Chen, man, 29 years old, patient started to occur pharyngalgia after suffering from cold before 2 days, when swallowing, the pain increased, malaise, dizzy, without heating fear of cold, without nasal obstruction watery nasal discharge, without nausea and vomiting, without cardiopalmus tachypnea, through looking into tonsil III degree of enlargement, be diagnosed as acute tonsillitis.The granule of oral administration inventive embodiments 1, each 15g, every day 3 times, take clinical symptoms and sign after 3 days and disappear, body temperature, numeration of leukocyte, tonsil recover normal, and clinical diagnosis is fully recovered.Follow up a case by regular visits to 3 months without recurrence.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (8)

1. treat the Chinese medicine preparation of acute tonsillitis for one kind, it is characterized in that, described Chinese medicine preparation comprises following raw medicinal material: Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae, Herba Psychotriae Siamicae, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw., Radix decaisneae fargesii, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herb Gynostemmae Pentaphylli, Herba Selaginellae Involventis, Herba Houttuyniae, Radix Cudraniae, Rhizoma Schizocapsae Plantagineae, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Radix radermacherae sinicae, Herba Cardui Crispi, Radix Antenoronis Filiformis, Radix et Rhizoma Thalictri, Herba Bulbophylli Odoratissim, Herba Polygoni Capitati and Radix et Rhizoma Dispori Cantoniensis.
2. Chinese medicine preparation as claimed in claim 1, it is characterized in that, the ratio of weight and number of described raw medicinal material is: Uroctea compatilis Koch. 15 ~ 25 parts, Herba Dichondrae Repentis 10 ~ 25 parts, disinfectant 15 ~ 30 parts, Herba Sedi Multicaulis 20 ~ 30 parts, Semen Plantaginis 10 ~ 25 parts, Herba Rorippae 15 ~ 30 parts, Herba Psychotriae Siamicae 10 ~ 20 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 15 ~ 25 parts, Radix decaisneae fargesii 20 ~ 30 parts, Herba Sonchi Arvensis 15 ~ 25 parts, Herba Arundinae Chinensis 10 ~ 25 parts, Rhizoma Bistortae 10 ~ 20 parts, Herb Gynostemmae Pentaphylli 20 ~ 35 parts, Herba Selaginellae Involventis 15 ~ 30 parts, Herba Houttuyniae 10 ~ 30 parts, Radix Cudraniae 10 ~ 25 parts, Rhizoma Schizocapsae Plantagineae 15 ~ 25 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 20 ~ 30 parts, Radix radermacherae sinicae 5 ~ 15 parts, Herba Cardui Crispi 10 ~ 25 parts, Radix Antenoronis Filiformis 10 ~ 30 parts, Radix et Rhizoma Thalictri 10 ~ 25 parts, Herba Bulbophylli Odoratissim 20 ~ 35 parts, Herba Polygoni Capitati 10 ~ 20 parts and Radix et Rhizoma Dispori Cantoniensis 15 ~ 25 parts.
3. Chinese medicine preparation as claimed in claim 1 or 2, it is characterized in that, the ratio of weight and number of described raw medicinal material is: Uroctea compatilis Koch. 15 ~ 20 parts, Herba Dichondrae Repentis 20 ~ 25 parts, disinfectant 20 ~ 30 parts, Herba Sedi Multicaulis 25 ~ 30 parts, Semen Plantaginis 15 ~ 25 parts, Herba Rorippae 15 ~ 25 parts, Herba Psychotriae Siamicae 15 ~ 20 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 20 ~ 25 parts, Radix decaisneae fargesii 20 ~ 25 parts, Herba Sonchi Arvensis 20 ~ 25 parts, Herba Arundinae Chinensis 15 ~ 20 parts, Rhizoma Bistortae 10 ~ 15 parts, Herb Gynostemmae Pentaphylli 20 ~ 30 parts, Herba Selaginellae Involventis 20 ~ 30 parts, Herba Houttuyniae 15 ~ 25 parts, Radix Cudraniae 10 ~ 20 parts, Rhizoma Schizocapsae Plantagineae 15 ~ 20 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 25 ~ 30 parts, Radix radermacherae sinicae 10 ~ 15 parts, Herba Cardui Crispi 15 ~ 25 parts, Radix Antenoronis Filiformis 20 ~ 30 parts, Radix et Rhizoma Thalictri 15 ~ 25 parts, Herba Bulbophylli Odoratissim 20 ~ 30 parts, Herba Polygoni Capitati 15 ~ 20 parts and Radix et Rhizoma Dispori Cantoniensis 20 ~ 25 parts.
4. the Chinese medicine preparation as described in claims 1 to 3, it is characterized in that, the ratio of weight and number of described raw medicinal material is: Uroctea compatilis Koch. 18 parts, Herba Dichondrae Repentis 23 parts, disinfectant 25 parts, Herba Sedi Multicaulis 25 parts, Semen Plantaginis 21 parts, Herba Rorippae 15 parts, Herba Psychotriae Siamicae 19 parts, Botrypus virginianus(L.)Holub[Osmunda virginiana L,Botrychium virginianum(L.) Sw. 22 parts, Radix decaisneae fargesii 23 parts, Herba Sonchi Arvensis 21 parts, Herba Arundinae Chinensis 17 parts, Rhizoma Bistortae 13 parts, Herb Gynostemmae Pentaphylli 25 parts, Herba Selaginellae Involventis 26 parts, Herba Houttuyniae 20 parts, Radix Cudraniae 15 parts, Rhizoma Schizocapsae Plantagineae 18 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 27 parts, Radix radermacherae sinicae 13 parts, Herba Cardui Crispi 20 parts, Radix Antenoronis Filiformis 25 parts, Radix et Rhizoma Thalictri 20 parts, Herba Bulbophylli Odoratissim 25 parts, Herba Polygoni Capitati 15 parts and Radix et Rhizoma Dispori Cantoniensis 22 parts.
5. the Chinese medicine preparation as described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is granule, and its preparation method comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 ~ 6 times, mixture is the ethanol of 80% ~ 95%, be heated to boiling reflux 4 ~ 6 hours, filter, take backflow as solvent, take filtering residue as solute, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.08Mpa, relative density is the mastic of 1.05 ~ 1.10, spraying dry, the inlet temperature of spray dryer 160 ~ 175 DEG C, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder,
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes granule, in 40 ~ 50 DEG C of dryings, obtains granule.
6. the Chinese medicine preparation as described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is syrup, and its preparation method comprises the following steps:
The first step, by Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae and Herba Psychotriae Siamicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,
Second step, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herba Selaginellae Involventis, Herba Houttuyniae and Radix Cudraniae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;
3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;
4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.
7. a preparation method for the Chinese medicine preparation described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is granule, and it comprises the following steps:
Step one: described raw medicinal material is mixed in described ratio, adding relative to the determining alcohol of 5 ~ 6 times, mixture is the ethanol of 80% ~ 95%, be heated to boiling reflux 4 ~ 6 hours, filter, take backflow as solvent, take filtering residue as solute, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being evaporated to 50 ~ 60 DEG C subsequently under vacuum 0.06 ~ 0.08Mpa, relative density is the mastic of 1.05 ~ 1.10, spraying dry, the inlet temperature of spray dryer 160 ~ 175 DEG C, leaving air temp 80 ~ 85 DEG C, be ground into powder subsequently, make dried cream powder,
Step 2: the dextrin adding cane sugar powder relative to dried cream powder quality 0.2 ~ 0.4 times and 0.1 ~ 0.2 times in the dried cream powder obtained, makes granule, in 40 ~ 50 DEG C of dryings, obtains granule.
8. a preparation method for the Chinese medicine preparation described in Claims 1-4, is characterized in that, the dosage form of described Chinese medicine preparation is syrup, and its preparation method comprises the following steps:
The first step, by Uroctea compatilis Koch., Herba Dichondrae Repentis, disinfectant, Herba Sedi Multicaulis, Semen Plantaginis, Herba Rorippae and Herba Psychotriae Siamicae mix in described ratio, adding relative to the determining alcohol of 4 ~ 6 times, mixture is the ethanol of 80% ~ 90%, heating and refluxing extraction 2 ~ 4 times, each reflux, extract, 2 hours ~ 3 hours, merge extractive liquid, with the centrifugal remove impurity of tube centrifuge, when the extracting solution after remove impurity being evaporated under the condition of 60 DEG C ~ 70 DEG C 60 DEG C, relative density is the medicinal liquid of 1.05 ~ 1.10, by dry with spray dryer for the concentrated solution after concentrated, be ground into 100 ~ 200 orders subsequently, obtain dry powder,
Second step, Herba Sonchi Arvensis, Herba Arundinae Chinensis, Rhizoma Bistortae, Herba Selaginellae Involventis, Herba Houttuyniae and Radix Cudraniae are mixed in described ratio, be ground into powder, be that the ethanol of 85% ~ 95% is as solvent with determining alcohol, flood 48 hours ~ 72 hours, adopt percolation with the speed of 1 ~ 2ml per minute slowly percolation, collect percolate, when being concentrated into 60 DEG C, relative density is the mastic of 1.25 ~ 1.27, dry with spray dryer, be ground into 100 ~ 200 orders subsequently, obtain dry powder, the quality of the ethanol added is 3 ~ 5 times of second step mixture quality;
3rd step, surplus stock medical material is mixed in described ratio, add relative to mixture 4 ~ 6 times amount determining alcohol be 70% ~ 80% alcohol reflux 2 ~ 4 times, each 1 hour ~ 3 hours, filter, filtrate merges, reclaim ethanol, when being concentrated into 60 DEG C, relative density is the mastic of 1.20 ~ 1.22, in 55 DEG C ~ 65 DEG C reduced vacuum dryings, obtains dry powder;
4th step, by the dry powder blend that the first step obtains to the 3rd step, add the water dissolution relative to mixture quality 3 ~ 5 times, by 40% sodium hydroxide solution adjust ph to 7.0, add correctives sucrose, antiseptic mix homogeneously subsequently, obtain syrup, the correctives added, antiseptic and the content in medicine thereof: sucrose 35 ~ 60%, Pyrusussuriensis acids antiseptic are if potassium sorbate 0.1 ~ 0.3%, paraben preservative are as ethyl hydroxybenzoate 0.01 ~ 0.05%.
CN201510874933.8A 2015-12-02 2015-12-02 Traditional Chinese medicine preparation for treating acute tonsillitis and preparation method thereof Pending CN105267687A (en)

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Publication number Priority date Publication date Assignee Title
CN105663860A (en) * 2016-03-17 2016-06-15 张敏 Traditional Chinese medicine for treating chronic viral hepatitis C and preparing method of traditional Chinese medicine

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CN101194944A (en) * 2006-12-05 2008-06-11 凌沛学 Technique of preparing medicament for treating upper respiratory tract infection and quality control method
CN103127405A (en) * 2012-12-20 2013-06-05 刘登富 Chinese materia medica preparation for treating child acute upper respiratory infection
CN104523852A (en) * 2014-12-18 2015-04-22 中国人民解放军第二军医大学 Anti-cold traditional Chinese medicine composition and application thereof

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Publication number Priority date Publication date Assignee Title
CN101194944A (en) * 2006-12-05 2008-06-11 凌沛学 Technique of preparing medicament for treating upper respiratory tract infection and quality control method
CN103127405A (en) * 2012-12-20 2013-06-05 刘登富 Chinese materia medica preparation for treating child acute upper respiratory infection
CN104523852A (en) * 2014-12-18 2015-04-22 中国人民解放军第二军医大学 Anti-cold traditional Chinese medicine composition and application thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105663860A (en) * 2016-03-17 2016-06-15 张敏 Traditional Chinese medicine for treating chronic viral hepatitis C and preparing method of traditional Chinese medicine

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Application publication date: 20160127