CN106620519A - Drug for treating mammitis and preparation method thereof - Google Patents

Abstract

The invention discloses a drug for treating mammitis and a preparation method thereof; the drug is mainly prepared from trichosanthes kirilowii maxim, dandelion, astragalus membranaceus, selfheal spike, burdock, oldenlandia diffusa, ligusticum wallichii, green tangerine peel, fructus forsythia, spina gleditsiae, cowherb seed, herba violae, angelica sinensis, scutellaria baicalensis, radix bupleuri, white atractylodes rhizome, radix curcumae, polygonum multiflorum, safflower carthamus, smoked plum, and herba leonuri according to a certain weight ratio. The drug is capable of clearing away heat and toxic materials, tonifying spleen and stomach, clearing liver and removing stasis, promoting circulation of blood and restoring menstrual flow, diminishing swelling and restraining sore; the drug is used for treating mammitis, and has quick and good effect, and the disease is not relapsed.

Description

It is a kind of to treat medicine of mastitis and preparation method thereof

Technical field

The present invention relates to a kind of treat medicine of mastitis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Mastitis is the common disease of women, and galactostasis is the prelude of bacterium infection and basis.Hyperlactation, milk ejection is not Freely, milk can deposit blocking, and the milk of alluvial is the best culture medium of bacterium.Have a delicate constitution immunity degradation, and parcel is too tight, goes out Sweat is more, and cleaning is inadequate, and breast local is moist, and also the growth and breeding for bacterium provides hotbed.The traditional Chinese medical science then think mastitis with Liver stomach intrinsic heat, exopathogen invasion and attack, stagnation of the circulation of vital energy heat is stopped up, and excessive noxious heat is relevant.Due to western medicine large side effects, therefore people are to effectively controlling There is great demand in the Chinese medicine for treating mastitis, up to now, it has not been found that with regard to the relevant report of the present invention.

The content of the invention

The present inventor have found effectively treatment mammary gland finally according to the checking repeatedly of research and the clinical testing of theory of traditional Chinese medical science Scorching medicine, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment mastitis.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention be select Snakegourd Fruit, dandelion, the Radix Astragali, selfheal, great burdock achene, oldenlandia diffusa, Ligusticum wallichii, rascal, The capsule of weeping forsythia, spina gleditsiae, the seed of cowherb, Chinese violet, Radix Angelicae Sinensis, the root of large-flowered skullcap, radix bupleuri, the bighead atractylodes rhizome, root tuber of aromatic turmeric, balloonflower root, fritillaria thunbergii, luffa, breast Perfume, myrrh, moutan bark, radix rehmanniae recen, the red sage root, the root of Dahurain angelica, the fleece-flower root, safflower, dark plum, motherwort, windproof, mother chrysanthemum, cornu cerve degelatinatum enter Prepared by row combination, cause each efficacy of drugs to produce synergy these drug regimens such that it is able to effectively treatment mastitis. Wherein it is because that its nature and flavor is sweet, slight bitter from Snakegourd Fruit, trembles with fear, return lung, stomach, large intestine channel has clearing away heat and eliminating phlegm, and relieving stuffiness of the chest by dispersing aggregation of pathogens moisturizes cunning The function of intestines, controls cough with lung heat, and the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, acute appendicitis, constipation.From dandelion Its nature and flavor bitter sweet is because, is trembled with fear, enter liver, stomach have clearing heat and detoxicating, and the function of diuresis dissipating bind controls acute mastitis, lymph gland Inflammation, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, gall-bladder Inflammation, urinary tract infections.It is because that its nature and flavor is sweet from the Radix Astragali, tepor enters lung, the spleen channel, raw to defend solid table, inducing diuresis for removing edema, support with beneficial Poison, the function of myogenic controls spontaneous perspiration, and night sweat, blood-arthralgia, edema, ulcer is not burst or burst and holds back long；Process with the function of having bowl spares benefit, control interior Hinder overstrain, splenasthenic diarrhea, prolapse of the anus, deficiency of vital energy blood takes off, collapse band and the disease of all laboured breathing deficiency of blood.It is because that its nature and flavor is bitter from selfheal It is pungent, to tremble with fear, enter liver, gallbladder channel have clearing liver, and the function of dissipating bind controls scrofula, and goiter and tumor, acute mastitis, breast cancer, mesh pearl nyctalgia, photophobia is shed tears, head It is dizzy dizzy, facial paralysis, arthralgia and myalgia, pulmonary tuberculosis, acute icteric catarrhal jaundice, metrorrhagia, under band.From great burdock achene be because It is arduous for its nature and flavor, it is cool, enter lung, stomach, there is dispelling wind and heat from the body, declare lung promoting eruption, the function of subdhing swelling and detoxicating to control cough due to wind-heat evil, throat Swell and ache, macula is impermeable, rubella is had an itch, carbuncle sore tumefacting virus.Its nature and flavor bitter sweet is because from oldenlandia diffusa, is trembled with fear, enter the heart, liver, spleen Three Jing, there is heat-clearing, and dampness removing, the function of removing toxic substances controls dyspnea and cough due to lung-heat, tonsillitis, sphagitis, appendicitis, dysentery, jaundice, pelvic cavity Inflammation, adnexitis, carbuncle swells furunculosis, venomous snake bite.It is because that its nature and flavor is pungent from Ligusticum wallichii, temperature, enter liver, gallbladder channel have promote breath and open depression, dispel Wind-dryness is wet, the function of promoting blood circulation and stopping pain, controls air-cooled headache rotation and swoons, hypochondriac pain abdomen pain, arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block Bitterly, ulcer sores.Its nature and flavor toil is because from rascal, tepor, enter liver, gallbladder channel have soothing the liver relieving stagnant Qi, the work(of dissipating bind dissolving phlegm Can, chest side of body gastral cavity pain is controlled, hernia, dyspepsia, breast is swollen, newborn core, chronic malaria addiction block.It is because that its nature and flavor is bitter from the capsule of weeping forsythia, it is cool, enter The heart, liver, gallbladder channel, there is heat-clearing, and removing toxic substances, dissipating bind, the function of detumescence controls warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching Close.It is because that its nature and flavor is pungent from spina gleditsiae, temperature searches wind, draws out pus by applying a plaster to the affected part, and subsides a swelling, and the function of apocenosis controls carbuncle swells, sore, pestilential wind, Tinea sore, retention of afterbirth.It is because that its nature and flavor is bitter flat from the seed of cowherb, enter liver, stomach have promoting circulation of blood to stimulate the menstrual flow, and expedite the emergence of lower breast, detumescence The function of sore, controls women's Amenorrhea, alactation, difficult labour, blood strangury, carbuncle swells, metal-inflicted wound bleeding.Its property is because from Chinese violet Taste bitter, acrid, cold, the thoughts of returning home, Liver Channel have clearing heat and detoxicating, the function of cool blood detumescence, control furuncle swelling toxin, ulcer carbuncle on the back, erysipelas, poisonous snake Bite.Its nature and flavor sweet, acrid, warm is because from Radix Angelicae Sinensis, enter the heart, liver, the spleen channel have a benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation Function, controls irregular menstruation, and Amenorrhea stomachache ， Disorder lump in the abdomen knots are poly-, and uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, intestinal dryness is difficult just, weight after dysentery characterized by blood in the stool, Ulcer sores, metal-inflicted wound, injury from falling down.Its nature and flavor bitter cold is because from the root of large-flowered skullcap, enters cardiopulmonary, courage, large intestine channel, had and rush down excess fire, removed Damp and hot, the function of arresting bleeding and miscarriage prevention controls high fever polydipsia, cough with lung heat.It is because that its nature and flavor is bitter from radix bupleuri, cool, enter liver, gallbladder channel, Soothing the liver in having and inducing sweat, the function of rising Yang controls fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, and lower profit is de- Anus, irregular menstruation, metroptosis.Its nature and flavor bitter sweet is because from the bighead atractylodes rhizome, temperature enters spleen, stomach, there is a tonifying spleen, beneficial stomach, eliminating dampness, Function with, controls deficient QI of the spleen and stomach, do not feel like eating, and burnout lacks gas, empty swollen, has loose bowels, phlegm and retained fluid, oedema, jaundice, arthritis with fixed pain caused by dampness, and urine is not Profit, dizzy, spontaneous perspiration, nausea is uneasy.It is because that its nature and flavor is worked hard from root tuber of aromatic turmeric, cool, enter the heart, lung, Liver Channel have promoting the circulation of qi solution with cool The function of blood broken stasis of blood, controls all pains of chest and abdomen side of body rib, and the mistake heart is demented, and pyreticosis coma is spitted blood, bleeding from five sense organs or subcutaneous tissue, hematuria, blood strangury, and women's vicarious menstruation is yellow Subcutaneous ulcer.Its nature and flavor toil is because from balloonflower root, is put down, enter lung, stomach, there is out a surname's lung qi, the function of eliminating the phlegm apocenosis is controlled diseases caused by external factors and coughed Cough, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache.Fritillaria thunbergii is because that its nature and flavor is bitter, is slightly cold, and return lung, the heart channel of Hang-Shaoyin have Heat-clearing dissipating bind, the function of preventing phlegm from forming and stopping coughing controls wind-heat affecting lung, and phlegm-fire cough, lung carbuncle, acute mastitis, scrofula, sore, ambition is gloomy.From Luffa is because that its nature and flavor is sweet, puts down, and has clearing and activating the channels and collaterals, and the function of clearing heat and eliminating phlegm controls pain in chest and hypochondrium, and stomachache, pain in the back, testis swells Bitterly, lung heat productive cough, women's Amenorrhea, alactation, carbuncle swells, anal fistula.From frankincense be because its nature and flavor work hard, temperature, enter the heart, liver, The spleen channel, there is regulating qi and activating blood, and analgesic therapy, the function of chasing after poison controls qi and blood stagnation, and trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, dysmenorrhoea is produced Hemostasis shouting pain afterwards.It is because that its nature and flavor is bitter from myrrh, puts down, enter Liver Channel, there are scattered blood stasis eliminatings, the function of detumescence ding-tong is controlled and falls damage, Metal-inflicted wound, muscles and bones, all Tong ， Disorder lumps in the abdomen of trusted subordinate, Amenorrhea, ulcer sore pain, anal fistula, mesh barrier.It is because that its nature and flavor is worked hard from moutan bark, Cool, enter the heart, liver and kidney channel have heat-clearing, cool blood, and blood, and the function of disappear the stasis of blood controls heat invading xuefen, send out spot ， Jing Epilepsy, tell, be defeated in battle, have blood in stool, Hectic fever due to yin labor heat, Amenorrhea ， Disorder lumps in the abdomen, large carbuncle flutters damage.It is because that its nature and flavor is sweet from radix rehmanniae recen, trembles with fear, the thoughts of returning home, liver and kidney channel has heat-clearing Cool blood, yin-nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, Heat Diabetes is spitted blood, and bleeding from five sense organs or subcutaneous tissue is sent out spot and sent out Rash.It is because that its nature and flavor is bitter from the red sage root, tepor, enter the heart, Liver Channel have a blood circulation and promoting silt, calming heart and tranquilizing mind, apocenosis, the function of pain relieving, Control angina pectoris, irregular menstruation, dysmenorrhoea, to close, metrorrhagia under band ， Disorder lumps in the abdomen, accumulation, abdominal pain due to blood stasis, arthralgia, shock palpitation not sleep is disliked Pyogenic infections from tumour or sore.It is because that its nature and flavor is pungent from the root of Dahurain angelica, temperature enters lung, spleen, stomach, there is wind-dispelling, eliminating dampness, detumescence, the function of pain relieving is controlled Headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin is dry itches, mange.Choosing It is because that its nature and flavor bitter sweet is puckery with the fleece-flower root, tepor enters liver and kidney channel, there is tonifying liver, kidney-nourishing, blood-nourishing, the function of wind-dispelling controls liver kidney Yin deficiency, sending out must be early white, and the deficiency of blood is dizzy, and waist and knee is weak, and muscles and bones is ached, and passes out semen, and collapses band, chronic malaria, protracted dysentery, chronic hepatitis, carbuncle swells, scrofula Scrofula, intestines wind, haemorrhoids.It is because that its nature and flavor is pungent from safflower, temperature, enter the heart, Liver Channel have invigorate blood circulation, and the function of stasis eliminatings pain relieving is controlled Amenorrhea ， Disorder lumps in the abdomen, difficult labour, stillborn foetus, disease that postpartum lochia can't go, hemostasis is had a pain, carbuncle swells, injury from falling down.Its nature and flavor is because from dark plum Acid, temperature, enter liver, spleen, lung, large intestine channel has convergence to promote the production of body fluid, the function of claming ascaris expelling parasite, controls chronic cough, abnormal heat polydipsia, chronic malaria, dysentery, Have blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, hookworm disease, psoriasis, the triangular mass of mucous membrane growing from the inner corner of the eye.It is because that its nature and flavor is worked hard from motherwort, It is cool, enter pericardium, Liver Channel, there is promoting blood circulation, dissolving stasis, menstruation regulating, the function of the water that disappears controls irregular menstruation, controls and Lou has difficult labour, placenta retension, postpartum Bruise, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria rushes down blood, carbuncle swells sore.Be because its property acrid-sweet flavor from windproof, temperature, enter bladder, Lung, the spleen channel, deliver, wind-dispelling, win wet, the function of pain relieving, control and catch cold, and have a headache, dizzy, Xiang Qiang, wind-cold-dampness arthralgia, joint acid Bitterly, four limbs contraction urgency, lockjaw.Its nature and flavor toil is because from mother chrysanthemum, it is cool, enter lung, Liver Channel, there are wind and heat dispersing, detumescence solution The function of poison, controls anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, malignant boil, carbuncle, aphtha, erysipelas, eczema, epidemic blisters.From Cornu cerve degelatinatum is because that its nature and flavor is salty, temperature, enters liver and kidney channel, there is qi-restoratives, and supporing yang function controls the insufficiency of the kidney yang, ache of the spinal column, taste The cold of insufficiency type, vomiting, anorexia and loose stool, uterus void is cold, uterine bleeding under band.

Specific embodiment

The drug dose of instant component is also that inventor summarizes what is drawn through groping in a large number, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount：

15-25 gram of Snakegourd Fruit, 10-20 gram of dandelion, 15-25 gram of the Radix Astragali, 10-20 gram of selfheal, 10-20 gram of great burdock achene, long-noded pit viper 10-20 gram of tongue grass, 5-15 gram of Ligusticum wallichii, 10-15 gram of rascal, 5-15 gram of the capsule of weeping forsythia, 10-15 gram of spina gleditsiae, 10-20 gram of the seed of cowherb, 5-15 gram of Chinese violet, 5-15 gram of Radix Angelicae Sinensis, 5-15 gram of the root of large-flowered skullcap, 5-15 gram of radix bupleuri, 10-20 gram of the bighead atractylodes rhizome, 7-12 gram of root tuber of aromatic turmeric, balloonflower root 10-15 gram, 5-15 gram of fritillaria thunbergii, 10-20 gram of luffa, 5-15 gram of frankincense, 5-15 gram of myrrh, 5-15 gram of moutan bark, radix rehmanniae recen 5-15 gram, 10-20 gram of the red sage root, 10-15 gram of the root of Dahurain angelica, 10-20 gram of the fleece-flower root, 5-15 gram of safflower, 5-15 gram of dark plum, motherwort 10- 15 grams, windproof 7-12 gram, 10-20 gram of mother chrysanthemum, 10-20 gram of cornu cerve degelatinatum.

Preferably：

20 grams of Snakegourd Fruit, 15 grams of dandelion, 20 grams of the Radix Astragali, 15 grams of selfheal, 15 grams of great burdock achene, 15 grams of oldenlandia diffusa, Ligusticum wallichii 10 Gram, 12 grams of rascal, 10 grams of the capsule of weeping forsythia, 12 grams of spina gleditsiae, 15 grams of the seed of cowherb, 10 grams of Chinese violet, 10 grams of Radix Angelicae Sinensis, 10 grams of the root of large-flowered skullcap, 10 grams of radix bupleuri, 15 grams of the bighead atractylodes rhizome, 9 grams of root tuber of aromatic turmeric, 12 grams of balloonflower root, 10 grams of fritillaria thunbergii, 15 grams of luffa, 10 grams of frankincense, 10 grams of myrrh is male 10 grams of the root bark of tree peony, 10 grams of radix rehmanniae recen, 15 grams of the red sage root, 12 grams of the root of Dahurain angelica, 15 grams of the fleece-flower root, 10 grams of safflower, 10 grams of dark plum, motherwort 12 Gram, windproof 9 grams, 15 grams of mother chrysanthemum, 15 grams of cornu cerve degelatinatum.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, Snakegourd Fruit：Crude drug, removing impurity and carpopodium, clean, flattening, chopping or fritter are taken, is dried；

2nd, dandelion：Impurity is picked, soil is cleaned, segment is dried；

3rd, the Radix Astragali：Net impurity is picked, the root head and hollow the greater of residual is removed, is soaked in water, pulled out, section in time after running through, Dry；

4th, selfheal：Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out；

5th, great burdock achene：Impurity is picked, spare is weeded out；

6th, oldenlandia diffusa：Crude drug is taken, impurity is removed, wash quickly is net, slightly dries in the air, segment is dried, and weeds out grey bits；

7th, Ligusticum wallichii：Impurity is picked, separates large and small, be soaked in water, solarization is dried in the air, cut into slices after vexed profit, be dried；

8th, rascal：Net impurity is picked, is soaked in water, pulled out, run through, cut into slices, dried；

9th, the capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；

10th, spina gleditsiae：Impurity is picked, is soaked in water, cut into slices after running through, dried；

11st, the seed of cowherb：Winnow with a dustpan net impurity, put in pot, fried to popping with slow fire and taken out when spending six, seventy percent in vain, cool；

12nd, Chinese violet：Crude drug is taken, impurity is removed, is cleaned, slightly dried in the air, segment is dried；

13rd, Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；

14th, the root of large-flowered skullcap：Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiling water with cold water and pull out, cut into slices, dried；

15th, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, section in time, dries immediately after running through；

16th, the bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

17th, root tuber of aromatic turmeric：It is soaked in water, cleans, pull solarization out and dry in the air, run through, cut into slices, dries；

18th, balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；

19th, fritillaria thunbergii：Impurity is removed, size stepping is cleaned, run through, and cuts sheet, is dried, and chip is removed in street, or is smashed；

20th, luffa：Clean and dry, segment；

21st, frankincense：Pick sand impurity；

22nd, myrrh：Impurity is picked, fragment is broken into；

23rd, moutan bark：Impurity is picked, core is removed, is cleaned, run through, cut into slices, dried；

24th, radix rehmanniae recen：Impurity is removed, is cleaned, slightly moistened, cut sheet, be dried, weed out chip；

25th, the red sage root：Net impurity is picked, rhizome is removed, is cleaned, pulled out, cut into slices after running through, dried；

26th, the root of Dahurain angelica：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried；

27th, the fleece-flower root：Impurity is picked, is cleaned, pulled out with bubble to eighty per cant thoroughly, moisten uniform to inside and outside humidity, cut into slices or the side of being cut into Block, dries；

28th, safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, is dried；

29th, dark plum：Net impurity is picked, grey bits are weeded out, is cleaned, dried；

30th, motherwort：Impurity is picked, is cleaned, run through, segment is dried；

31st, it is windproof：Residual stem is removed, is soaked in water, pulled out, run through section, dried；

32nd, mother chrysanthemum：Impurity is removed, undesirable root is removed, segment is cleaned, is dried；

33rd, cornu cerve degelatinatum：Impurity is picked, fritter is hacked into.

2nd, prepare

1st, by the Snakegourd Fruit after processing, dandelion, the Radix Astragali, selfheal, great burdock achene, oldenlandia diffusa, Ligusticum wallichii, rascal, the capsule of weeping forsythia, Chinese honey locust It is thorn, the seed of cowherb, Chinese violet, Radix Angelicae Sinensis, the root of large-flowered skullcap, radix bupleuri, the bighead atractylodes rhizome, root tuber of aromatic turmeric, balloonflower root, fritillaria thunbergii, luffa, frankincense, myrrh, male The root bark of tree peony, radix rehmanniae recen, the red sage root, the root of Dahurain angelica, the fleece-flower root, safflower, dark plum, motherwort, windproof, mother chrysanthemum, cornu cerve degelatinatum are put into decocting container It is interior, add water for the first time 8 times and measure, after soaking 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain for the first time Decoction liquor, first time decoction liquor is poured in container；

2nd, the dregs of a decoction of filtration are added into 6 times of amounts, is boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

3rd, will decoction liquor mixing and stirring twice, be divided into 4 doses and take.

Dandelion has clearing heat and detoxicating in prescription, and the function of diuresis dissipating bind is monarch drug in a prescription；Selfheal clears liver, dissipating bind；The bighead atractylodes rhizome has benefit Spleen, beneficial stomach, eliminating dampness, and in function, the two is ministerial drug, and three taste medicines play clearing heat and detoxicating jointly, clearing liver dissipating bind, tonifying spleen benefit stomach, Eliminating dampness, and in effect, comprehensively, and with clearing heat and detoxicating, tonifying spleen benefit stomach, Liver-Clearing Powder becomes master can effect a permanent cure treatment mastitis effect, Ligusticum wallichii has promote breath and open depression, dispels pathogenic wind and remove dampness, and the function of promoting blood circulation and stopping pain is adjutant, and the seed of cowherb has promoting circulation of blood to stimulate the menstrual flow, expedites the emergence of lower breast, is subsided a swelling The function of sore, to make medicine, is to take stopgap measures with remaining all medicines.

Medicine of the present invention has clearing heat and detoxicating, tonifying spleen benefit stomach, and clearing liver dissipating bind, promoting circulation of blood stimulates the menstrual flow, and the function of healing up sore and subduing swelling is used for Treatment mastitis, short treating period, instant effect, non-relapse after healing.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples are including this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and 15 per group, one of which is overdose test Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept mastitis out-patient totally 35 for medical treatment.

2nd, diagnostic criteria

Classical symptom is anxious for morbidity, lump can occurs with heating, chilly, sick side breast red and swollen heat pain, eventually forms abscess Deng.Be this mastitis symptom severe patient with high fever, shiver with cold, substantially, local skin is red and swollen for mastosis, there is scleroma, and tenderness is suffered from Side under-arm enlargement of lymph nodes, inflammation softens within a couple of days, forms breast and swells, and has fluctuation, the deep rubefaction of abscess and fluctuation Feel the symptom such as unobvious.

3rd, treatment method

From above-mentioned medicament, take to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 7 days a course for the treatment of, continuously clothes With 2 courses for the treatment of.

4th, efficacy assessment standard

It is effective：Mastitis symptom disappears, and physique recovers normal, recovery from illness；

Take a turn for the better：Patient generates heat, chilly, and breast is red and swollen, the symptom mitigation of lump, and mastitis symptom is clearly better, and physique is progressively extensive It is multiple；

It is invalid：Improvement standard person is not reached.

5th, treatment results（See the table below）

In above-mentioned treatment, with drug therapy mastitis patient 35 of the present invention, as a result effective 29, obvious effective rate is 82.85%, Take a turn for the better 4, improvement rate is 11.42%, and invalid 2, total effective rate is 94.27%.

Claims (3)

1. a kind of medicine for treating mastitis, it is characterised in that：It is made up of the bulk drug in following weight range：

15-25 gram of Snakegourd Fruit, 10-20 gram of dandelion, 15-25 gram of the Radix Astragali, 10-20 gram of selfheal, 10-20 gram of great burdock achene, long-noded pit viper 10-20 gram of tongue grass, 5-15 gram of Ligusticum wallichii, 10-15 gram of rascal, 5-15 gram of the capsule of weeping forsythia, 10-15 gram of spina gleditsiae, 10-20 gram of the seed of cowherb, 5-15 gram of Chinese violet, 5-15 gram of Radix Angelicae Sinensis, 5-15 gram of the root of large-flowered skullcap, 5-15 gram of radix bupleuri, 10-20 gram of the bighead atractylodes rhizome, 7-12 gram of root tuber of aromatic turmeric, balloonflower root 10-15 gram, 5-15 gram of fritillaria thunbergii, 10-20 gram of luffa, 5-15 gram of frankincense, 5-15 gram of myrrh, 5-15 gram of moutan bark, radix rehmanniae recen 5-15 gram, 10-20 gram of the red sage root, 10-15 gram of the root of Dahurain angelica, 10-20 gram of the fleece-flower root, 5-15 gram of safflower, 5-15 gram of dark plum, motherwort 10- 15 grams, windproof 7-12 gram, 10-20 gram of mother chrysanthemum, 10-20 gram of cornu cerve degelatinatum.

2. medicine according to claim 1, wherein the consumption of each bulk drug is：

20 grams of Snakegourd Fruit, 15 grams of dandelion, 20 grams of the Radix Astragali, 15 grams of selfheal, 15 grams of great burdock achene, 15 grams of oldenlandia diffusa, Ligusticum wallichii 10 Gram, 12 grams of rascal, 10 grams of the capsule of weeping forsythia, 12 grams of spina gleditsiae, 15 grams of the seed of cowherb, 10 grams of Chinese violet, 10 grams of Radix Angelicae Sinensis, 10 grams of the root of large-flowered skullcap, 10 grams of radix bupleuri, 15 grams of the bighead atractylodes rhizome, 9 grams of root tuber of aromatic turmeric, 12 grams of balloonflower root, 10 grams of fritillaria thunbergii, 15 grams of luffa, 10 grams of frankincense, 10 grams of myrrh is male 10 grams of the root bark of tree peony, 10 grams of radix rehmanniae recen, 15 grams of the red sage root, 12 grams of the root of Dahurain angelica, 15 grams of the fleece-flower root, 10 grams of safflower, 10 grams of dark plum, motherwort 12 Gram, windproof 9 grams, 15 grams of mother chrysanthemum, 15 grams of cornu cerve degelatinatum.

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Snakegourd Fruit：Crude drug, removing impurity and carpopodium, clean, flattening, chopping or fritter are taken, is dried；

（2）Dandelion：Impurity is picked, soil is cleaned, segment is dried；

（3）The Radix Astragali：Net impurity is picked, the root head and hollow the greater of residual is removed, is soaked in water, pulled out, section in time after running through, Dry；

（4）Selfheal：Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out；

（5）Great burdock achene：Impurity is picked, spare is weeded out；

（6）Oldenlandia diffusa：Crude drug is taken, impurity is removed, wash quickly is net, slightly dries in the air, segment is dried, and weeds out grey bits；

（7）Ligusticum wallichii：Impurity is picked, separates large and small, be soaked in water, solarization is dried in the air, cut into slices after vexed profit, be dried；

（8）Rascal：Net impurity is picked, is soaked in water, pulled out, run through, cut into slices, dried；

（9）The capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；

（10）Spina gleditsiae：Impurity is picked, is soaked in water, cut into slices after running through, dried；

（11）The seed of cowherb：Winnow with a dustpan net impurity, put in pot, fried to popping with slow fire and taken out when spending six, seventy percent in vain, cool；

（12）Chinese violet：Crude drug is taken, impurity is removed, is cleaned, slightly dried in the air, segment is dried；

（13）Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；

（14）The root of large-flowered skullcap：Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiling water with cold water and pull out, cut into slices, dried；

（15）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, section in time, dries immediately after running through；

（16）The bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

（17）Root tuber of aromatic turmeric：It is soaked in water, cleans, pull solarization out and dry in the air, run through, cut into slices, dries；

（18）Balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；

（19）Fritillaria thunbergii：Impurity is removed, size stepping is cleaned, run through, and cuts sheet, is dried, and chip is removed in street, or is smashed；

（20）Luffa：Clean and dry, segment；

（21）Frankincense：Pick sand impurity；

（22）Myrrh：Impurity is picked, fragment is broken into；

（23）Moutan bark：Impurity is picked, core is removed, is cleaned, run through, cut into slices, dried；

（24）Radix rehmanniae recen：Impurity is removed, is cleaned, slightly moistened, cut sheet, be dried, weed out chip；

（25）The red sage root：Net impurity is picked, rhizome is removed, is cleaned, pulled out, cut into slices after running through, dried；

（26）The root of Dahurain angelica：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut Piece is dried；

（27）The fleece-flower root：Impurity is picked, is cleaned, pulled out with bubble to eighty per cant thoroughly, moisten uniform to inside and outside humidity, cut into slices or be cut into Square, dries；

（28）Safflower：Net impurity is picked, cauline leaf, base of a fruit head is removed, is dried；

（29）Dark plum：Net impurity is picked, grey bits are weeded out, is cleaned, dried；

（30）Motherwort：Impurity is picked, is cleaned, run through, segment is dried；

（31）It is windproof：Residual stem is removed, is soaked in water, pulled out, run through section, dried；

（32）Mother chrysanthemum：Impurity is removed, undesirable root is removed, segment is cleaned, is dried；

（33）Cornu cerve degelatinatum：Impurity is picked, fritter is hacked into；

（Two）Prepare

（1）By the Snakegourd Fruit after processing, dandelion, the Radix Astragali, selfheal, great burdock achene, oldenlandia diffusa, Ligusticum wallichii, rascal, the capsule of weeping forsythia, soap Angle thorn, the seed of cowherb, Chinese violet, Radix Angelicae Sinensis, the root of large-flowered skullcap, radix bupleuri, the bighead atractylodes rhizome, root tuber of aromatic turmeric, balloonflower root, fritillaria thunbergii, luffa, frankincense, myrrh, Moutan bark, radix rehmanniae recen, the red sage root, the root of Dahurain angelica, the fleece-flower root, safflower, dark plum, motherwort, windproof, mother chrysanthemum, cornu cerve degelatinatum are put into appearance of boiling medicine In device, add water 8 times and measure, after soaking 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain decoction for the first time Liquid, first time decoction liquor is poured in container；

（2）The dregs of a decoction of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 4 doses and is taken.