CN105327296A - Medicine for treating peptic ulcer and preparing method of medicine - Google Patents
Medicine for treating peptic ulcer and preparing method of medicine Download PDFInfo
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- CN105327296A CN105327296A CN201510913424.1A CN201510913424A CN105327296A CN 105327296 A CN105327296 A CN 105327296A CN 201510913424 A CN201510913424 A CN 201510913424A CN 105327296 A CN105327296 A CN 105327296A
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Abstract
The invention discloses a medicine for treating a peptic ulcer and a preparing method of the medicine. The medicine is mainly prepared from cuttlebone, concha arcae, fritillary bulbs, radix cyathulae, codonopsis pilosula, dendrobe, jasmines, nightshade, radix paeoniae alba, fructus evodiae, rhizoma galangae, fleshfingered citron flowers, trogopterus dung, rhizome bletillae, deer-horn glue, hairyvein agrimony, the roots of three-nerved spicebush, morinda officinalis, fructus amomi, mangnolia officinalis, radix bupleuri, semen coicis, radix curcumae, rheum officinale, pharbitis seeds, fructus chebulae, cinnamon and fructus cannabis according to certain weight proportions. The medicine has the functions of tonifying middle-jiao and qi, hormnizing the stomach and enlivening the spleen, abating fever and soothing the liver, and treating weakness of the spleen and the stomach and deficiency of qi and blood, and is fast in effect taking and good in curative effect when being used for treating the peptic ulcer and the peptic ulcer is not prone to relapse.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of peptic ulcer and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Peptic ulcer refers to betide the duodenal chronic ulcer of harmonization of the stomach, is a frequently-occurring disease, commonly encountered diseases.Ulcer be formed with various factors, wherein the Digestion of acidic gastric juice to mucosa is the Fundamentals of ulcer.The traditional Chinese medical science then thinks peptic ulcer and incoordination between the liver and stomach, and damp-heat in the spleen and stomach, qi depression to blood stasis, Deficiency and coldness of spleen and stomach is relevant.Because western medicine side effect is large, therefore there is great demand to the Chinese medicine of effectively treating peptic ulcer in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment peptic ulcer, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment peptic ulcer.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Endoconcha Sepiae, Concha Arcae, Bulbus Fritillariae Thunbergii, Radix Cyathulae, Radix Codonopsis, Herba Dendrobii, Fructus Gardeniae, Herba Solani Nigri, the Radix Paeoniae Alba, Fructus Evodiae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae, Flos Citri Sarcodactylis, Oletum Trogopterori, Pseudobulbus Bletillae (Rhizoma Bletillae), Colla cornus cervi, Herba Agrimoniae, the Radix Linderae, Radix Morindae Officinalis, Fructus Amomi, Cortex Magnoliae Officinalis, Radix Bupleuri, Semen Coicis, Radix Curcumae, Radix Et Rhizoma Rhei, Semen Pharbitidis, Fructus Chebulae, Cortex Cinnamomi, Fructus Cannabis, Herba Taraxaci crude drug to carry out combination preparation, make each efficacy of drugs produce synergism the combination of these crude drug, thus effectively can treat peptic ulcer.Wherein, select Endoconcha Sepiae to be that tepor, enters liver, kidney channel, have dehumidifying, antacid because its nature and flavor are salty, hemostasis, the function of sore, treat for stomachache acid regurgitation, tells, is defeated in battle, hematemesis, has blood in stool, bleeding not during menses, amenorrhea due to blood depletion, Fu Tong mass in the abdomen, intermittent fever of deficiency type dysentery, the rotten skin ulcer of the erosion of the vulva.Concha Arcae is selected to be that flat, enter liver, spleen channel, have and reduce phlegm, softening the hard mass, dissipating blood stasis, the function of removing food stagnancy, controls accumulation of phlegm because its nature and flavor are sweet, salty, stomachache, noisy, acid regurgitation ， mass in the abdomen, scrofula, ulcerative gingivitis.Bulbus Fritillariae Thunbergii is selected to be that be slightly cold, return lung, heart channel, have heat clearing away eliminating stagnation, the function of preventing phlegm from forming and stopping coughing, controls wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore, and ambition is gloomy because its nature and flavor are bitter.Radix Cyathulae is selected to be that the micro-hardship of bitter in the mouth, nontoxic, enter liver, kidney two warp, dispel the wind, dampness removing, stimulates the menstrual flow, the function of invigorating blood circulation, dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea ， mass in the abdomen because its nature and flavor are put down.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Select Herba Dendrobii to be because its property slightly sweet flavor is micro-salty, cold, enter to have, lung, kidney channel, have the stomach reinforcing that promotes the production of body fluid, the function of clearing away heat and nourishing YIN, controls consumption of body fluid caused by febrile disease, and xerostomia is tired drinks, deficiency-heat after being ill, and it is dark that the moon hinders order.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, have heat clearing away, pathogenic fire purging, the function of removing heat from blood, control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Herba Solani Nigri to be because its nature and flavor are bitter, cold, have heat clearing away, removing toxic substances, invigorate blood circulation, the function of detumescence, controls furuncle, carbuncle, erysipelas, osteopatia sprain, chronic tracheitis, acute nephritis.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Fructus Evodiae to be because its nature and flavor are worked hard, temperature, poisonous, enter liver, stomach warp, have warming middle-JIAO, pain relieving, regulate the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Rhizoma Alpiniae Officinarum is selected to be that enter spleen, stomach warp, has stomach warming, dispels the wind, cold expelling, circulation of qi promoting, the function of pain relieving, and control taste invasion by pathogenic cold, coldness and pain in the epigastrium, vomiting is had loose bowels, dysphagia and regurgitation, dyspepsia, subtertian malaria, cold addiction because its property and flavor of peppery and warm.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Flos Citri Sarcodactylis to be because its nature and flavor are sad, temperature, has the function of activating QI to eliminate phlegm, treats for stomachache, coerce swollen, vomiting, dysphagic cough with asthma.Select Oletum Trogopterori to be because its property bitter but sweet flavor, temperature, enters liver, spleen channel, and raw by the function having promoting the circulation of blood pain relieving, control all pains of trusted subordinate's vim and vigour, women's amenorrhea, postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite, stir-fry is stopped blooding, and control metrorrhagia, menorrhagia, leucorrhea with bloody discharge is without cease.Select Pseudobulbus Bletillae (Rhizoma Bletillae) to be because its property bitter but sweet flavor, cool, enter lung meridian, have tonifying the lung, hemostasis, detumescence, raw sight, the function of sore, control lung and hinder hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, canker sores, and soup fire is burnt, rhagadia manus et pedis.Select Colla cornus cervi to be because its property sweet-salty, temperature, enters liver, kidney channel, enriches blood, and the function of benefit essence, controls deficiency of kidney-QI, asthenia weakness and emaciation, lumbago, carbuncle of yin nature, impotence in male, spermatorrhea, uterus cold caused by deficiency, metrorrhagia, leukorrhagia.Select Herba Agrimoniae to be because its nature and flavor toil, flat, enter lung, liver, spleen channel, have hemostasis, the function of stomach invigorating, controls spitting of blood, and spit blood, hematuria, has blood in stool, dysentery, bleeding not during menses, and impairment caused by overstrain takes off power, carbuncle, traumatic injury, wound hemorrhage.Select the Radix Linderae to be that temperature, enters spleen, lung, kidney, urinary bladder channel, have pleasant, dissipating depression of QI, cold expelling, the function of pain relieving, control QI rising in reverse order chest and abdomen swelling and pain because its nature and flavor are pungent, dyspepsia is discontented with, and food is told in regurgitation, colic of cold type, beriberi, frequent micturition.Select Radix Morindae Officinalis to be because its property acrid-sweet flavor, temperature, enter liver, kidney channel, have kidney-replenishing, strengthening bone and muscle, the function of wind-damp dispelling, controls sexual impotence, few abdomen cold type of pain, incontinence of urine, deficiency-cold of uterus, anemofrigid-damp arthralgia, soreness of waist and knee joint.Select Fructus Amomi to be that temperature, enters spleen, stomach warp because its nature and flavor are pungent, in having circulation of qi promoting to adjust, stomach function regulating, the function of being amusing, control stomachache painful abdominal mass swollen, anorexia dyspepsia, chokes every vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Radix Bupleuri to be by because its nature and flavor are bitter, be slightly cold, return liver, gallbladder meridian.Treating SHAO YANG disease by mediation, brings down a fever soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.Semen Coicis is selected to be that cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and have loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea because its property slightly sweet flavor.Radix Curcumae is selected to be because its nature and flavor are worked hard, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Radix Et Rhizoma Rhei is selected to be that enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant because its nature and flavor are bitter, cold, the function of clots absorbing blood, control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Semen Pharbitidis is selected to be that cold, poisonous, return lung, kidney, large intestine channel, have removing water retention by purgation relieving constipation, drink is washed in expectorant, and parasite killing attacks long-pending function, swelling pain of harnessing the river, constipation and anuresis, and phlegm retention is gathered, and QI rising in reverse order is breathed with cough, abdominal pain due to worm stagnation, ascarid, taeniasis because its nature and flavor are bitter.Select Fructus Chebulae to be because its nature and flavor picric acid is puckery, temperature, enters lung, stomach, large intestine channel, astringes the lung, astringing intestine to stop diarrhea, the function of the therapeutic method to keep the adverse QI flowing downwards, control chronic cough aphonia, chronic diarrhea, chronic dysentery, proctoptosis, have blood in stool, metrorrhagia, leukorrhagia, seminal emission, frequent micturition.Select Cortex Cinnamomi to be because its property acrid-sweet flavor, heat, enters kidney, spleen, urinary bladder channel, has complement sun, warming the spleen and stomach, removing accumulated cold, the function of promoting blood circulation, controls decline of the fire from the gate of life, cold extremities faint pulse, and YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Fructus Cannabis is selected to be that flat, enter spleen, stomach, large intestine channel, have and moisturize, laxation, treating stranguria, the function of invigorating blood circulation, control dryness of the intestine constipation, quench one's thirst, pyretic stranguria, migratory arthralgia, dysentery, menoxenia, scabies, tinea is insane because its nature and flavor are sweet.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Endoconcha Sepiae 15-25 gram, Concha Arcae 10-20 gram, Bulbus Fritillariae Thunbergii 15-25 gram, Radix Cyathulae 7-12 gram, Radix Codonopsis 10-20 gram, Herba Dendrobii 10-20 gram, Fructus Gardeniae 5-15 gram, Herba Solani Nigri 15-25 gram, Radix Paeoniae Alba 10-15 gram, Fructus Evodiae 10-20 gram, Rhizoma Alpiniae Officinarum 5-15 gram, Radix Glycyrrhizae 5-10 gram, Flos Citri Sarcodactylis 5-15 gram, Oletum Trogopterori 5-15 gram, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 gram, Colla cornus cervi 10-15 gram, Herba Agrimoniae 10-20 gram, Radix Linderae 5-10 gram, Radix Morindae Officinalis 10-15 gram, Fructus Amomi 5-15 gram, Cortex Magnoliae Officinalis 10-15 gram, Radix Bupleuri 5-15 gram, Semen Coicis 10-20 gram, Radix Curcumae 10-20 gram, Radix Et Rhizoma Rhei 5-15 gram, Semen Pharbitidis 5-15 gram, Fructus Chebulae 10-20 gram, Cortex Cinnamomi 5-15 gram, Fructus Cannabis 5-10 gram, Herba Taraxaci 7-12 gram.
Be preferably
Endoconcha Sepiae 20 grams, Concha Arcae 15 grams, Bulbus Fritillariae Thunbergii 20 grams, Radix Cyathulae 9 grams, Radix Codonopsis 15 grams, Herba Dendrobii 15 grams, Fructus Gardeniae 10 grams, Herba Solani Nigri 20 grams, the Radix Paeoniae Alba 12 grams, Fructus Evodiae 15 grams, Rhizoma Alpiniae Officinarum 10 grams, 8 grams, Radix Glycyrrhizae, Flos Citri Sarcodactylis 10 grams, Oletum Trogopterori 10 grams, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 grams, Colla cornus cervi 12 grams, Herba Agrimoniae 15 grams, the Radix Linderae 8 grams, Radix Morindae Officinalis 12 grams, Fructus Amomi 10 grams, Cortex Magnoliae Officinalis 12 grams, Radix Bupleuri 10 grams, Semen Coicis 15 grams, Radix Curcumae 15 grams, Radix Et Rhizoma Rhei 10 grams, Semen Pharbitidis 10 grams, Fructus Chebulae 15 grams, Cortex Cinnamomi 10 grams, Fructus Cannabis 8 grams, Herba Taraxaci 9 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Endoconcha Sepiae: scrub clean, dries, and pounds into fritter;
2, Concha Arcae: clean and dry, pulverize;
3, Bulbus Fritillariae Thunbergii: removing impurity, size stepping, cleans, runs through, cut sheet, dry, and sieve removes chip, smashes;
4, Radix Cyathulae: pick decontamination, dries;
5, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
6, Herba Dendrobii: get dry Herba Dendrobii, saturating with blister about to eighty per cant, moistening, removing undesirable root and black branch, cutting, hits thin film, dries;
7, Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve;
8, Herba Solani Nigri: get crude drug, removing is obstructed always, impurity, cleans, slightly moistens, cutting, dry;
9, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
10, Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;
11, Rhizoma Alpiniae Officinarum: pick clean impurity, washing, slightly soaks, pulls out, run through, and section, dries;
12, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
13, Flos Citri Sarcodactylis: gather during flower thinning before sunrise in morning, or pickup fallen flowers, dry or dry;
14, Oletum Trogopterori: pick clean impurity, smashes or sieves dedust bits;
15, Pseudobulbus Bletillae (Rhizoma Bletillae): pick decontamination, is soaked in water, and pulls out, dries in the air even to inside and outside humidity, and section is dry;
16, Colla cornus cervi: get crude drug, removing impurity, the used time smashs to pieces or levigation;
17, Herba Agrimoniae: removing impurity undesirable root, cleans, runs through, cut off, dry;
18, the Radix Linderae: pick decontamination, separately size bar, saturating with blister, changing water according to noting season, preventing smelly, pulling section out in time, sieve dedust bits;
19, Radix Morindae Officinalis: pick decontamination, after soaking, pumps core while hot, cutting, dry with hot water;
20, Fructus Amomi: pick decontamination and shell, smash to pieces;
21, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
22, Radix Bupleuri: get crude drug, removes residual stem, impurity, cleans, softens, cut sheet, dry, and sieve removes chip;
23, Semen Coicis: get crude drug, removing residual cot, impurity;
24, Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
25, Radix Et Rhizoma Rhei: get the Radix Et Rhizoma Rhei be cut into small pieces, former medicine picks clean impurity, size stepping, and moistening is even to inside and outside humidity, and section, dries;
26, Semen Pharbitidis: get crude drug, removing impurity, flat grain and shell, the used time smashs to pieces;
27, Fructus Chebulae: get crude drug, removing impurity, cleaning, drying;
28, Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
29, Fructus Cannabis: pick decontamination and residual shell, get clean core;
30, Herba Taraxaci: pick decontamination, clean earth, cutting, dries.
Two, prepare
1, the Endoconcha Sepiae after the process of preparing Chinese medicine, Concha Arcae, Bulbus Fritillariae Thunbergii, Radix Cyathulae, Radix Codonopsis, Herba Dendrobii, Fructus Gardeniae, Herba Solani Nigri, the Radix Paeoniae Alba, Fructus Evodiae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae, Flos Citri Sarcodactylis, Oletum Trogopterori, Pseudobulbus Bletillae (Rhizoma Bletillae), Colla cornus cervi, Herba Agrimoniae, the Radix Linderae, Radix Morindae Officinalis, Fructus Amomi, Cortex Magnoliae Officinalis, Radix Bupleuri, Semen Coicis, Radix Curcumae, Radix Et Rhizoma Rhei, Semen Pharbitidis, Fructus Chebulae, Cortex Cinnamomi, Fructus Cannabis, Herba Taraxaci are put into decocting container, add water 8 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, by twice decoction liquor mixing and stirring, 4 doses are divided into take.
In prescription, Radix Codonopsis has invigorating the spleen and replenishing QI, promotes the production of body fluid, and controls weakness of the spleen and stomach, and the function of deficiency of both QI and blood is monarch drug; Rhizoma Alpiniae Officinarum stomach warming, dispels the wind, cold expelling, circulation of qi promoting, controls taste invasion by pathogenic cold; During Fructus Amomi has circulation of qi promoting to adjust, stomach function regulating, the function of being amusing, the two is ministerial drug, three taste medicines play invigorating the spleen and replenishing QI, stomach warming jointly, dispel the wind, cold expelling, circulation of qi promoting, controls weakness of the spleen and stomach, deficiency of both QI and blood, stomach function regulating, the effect of being amusing, treatment peptic ulcer effect is comprehensive, and to control weakness of the spleen and stomach, deficiency of both QI and blood, stomach function regulating, to be amusing be that master can be effected a permanent cure, and Radix Bupleuri has treating SHAO YANG disease by mediation, brings down a fever soothing the liver, the function of yang invigorating is adjuvant drug, Radix Glycyrrhizae has and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, the function controlling weakness of the spleen and stomach, for making medicine, is take stopgap measures with all medicines of remainder.
Medicine of the present invention has invigorating the spleen and replenishing QI, and stomach function regulating is amusing, and brings down a fever soothing the liver, controls weakness of the spleen and stomach, and the function of deficiency of both QI and blood, is used for the treatment of peptic ulcer, short treating period, instant effect, non-relapse after healing.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Taking admixing medical solutions super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept peptic ulcer out-patient totally 28 examples for medical treatment.
2, diagnostic criteria
Classical symptom is chronic, and periodically, rhythmicity upper abdominal pain, other is belch, acid regurgitation, burn feeling after breastbone, sialorrhea, feels sick, vomiting, constipation, waits and separately or can accompany the symptoms such as pain appearance.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 7 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: peptic ulcer transference cure, body constitution recovers normal, recovery from illness;
Take a turn for the better: patient's upper abdominal pain, feel sick, vomiting, acid regurgitation, constipation, belch symptom alleviates, and peptic ulcer symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy Peptic Ulcers 30 example of the present invention, effective 24 examples of result, obvious effective rate is 85.71%, and take a turn for the better 3 examples, and improvement rate is 10.71%, and invalid 1 example, total effective rate is 96.42%.
Claims (3)
1. treat a medicine for peptic ulcer, it is characterized in that: it is made up of the crude drug in following weight range:
Endoconcha Sepiae 15-25 gram, Concha Arcae 10-20 gram, Bulbus Fritillariae Thunbergii 15-25 gram, Radix Cyathulae 7-12 gram, Radix Codonopsis 10-20 gram, Herba Dendrobii 10-20 gram, Fructus Gardeniae 5-15 gram, Herba Solani Nigri 15-25 gram, Radix Paeoniae Alba 10-15 gram, Fructus Evodiae 10-20 gram, Rhizoma Alpiniae Officinarum 5-15 gram, Radix Glycyrrhizae 5-10 gram, Flos Citri Sarcodactylis 5-15 gram, Oletum Trogopterori 5-15 gram, Pseudobulbus Bletillae (Rhizoma Bletillae) 5-15 gram, Colla cornus cervi 10-15 gram, Herba Agrimoniae 10-20 gram, Radix Linderae 5-10 gram, Radix Morindae Officinalis 10-15 gram, Fructus Amomi 5-15 gram, Cortex Magnoliae Officinalis 10-15 gram, Radix Bupleuri 5-15 gram, Semen Coicis 10-20 gram, Radix Curcumae 10-20 gram, Radix Et Rhizoma Rhei 5-15 gram, Semen Pharbitidis 5-15 gram, Fructus Chebulae 10-20 gram, Cortex Cinnamomi 5-15 gram, Fructus Cannabis 5-10 gram, Herba Taraxaci 7-12 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Endoconcha Sepiae 20 grams, Concha Arcae 15 grams, Bulbus Fritillariae Thunbergii 20 grams, Radix Cyathulae 9 grams, Radix Codonopsis 15 grams, Herba Dendrobii 15 grams, Fructus Gardeniae 10 grams, Herba Solani Nigri 20 grams, the Radix Paeoniae Alba 12 grams, Fructus Evodiae 15 grams, Rhizoma Alpiniae Officinarum 10 grams, 8 grams, Radix Glycyrrhizae, Flos Citri Sarcodactylis 10 grams, Oletum Trogopterori 10 grams, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 grams, Colla cornus cervi 12 grams, Herba Agrimoniae 15 grams, the Radix Linderae 8 grams, Radix Morindae Officinalis 12 grams, Fructus Amomi 10 grams, Cortex Magnoliae Officinalis 12 grams, Radix Bupleuri 10 grams, Semen Coicis 15 grams, Radix Curcumae 15 grams, Radix Et Rhizoma Rhei 10 grams, Semen Pharbitidis 10 grams, Fructus Chebulae 15 grams, Cortex Cinnamomi 10 grams, Fructus Cannabis 8 grams, Herba Taraxaci 9 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Endoconcha Sepiae: scrub clean, dries, and pounds into fritter;
(2) Concha Arcae: clean and dry, pulverize;
(3) Bulbus Fritillariae Thunbergii: removing impurity, size stepping, cleans, runs through, cut sheet, dry, and sieve removes chip, smashes;
(4) Radix Cyathulae: pick decontamination, dries;
(5) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(6) Herba Dendrobii: get dry Herba Dendrobii, saturating with blister about to eighty per cant, moistening, removing undesirable root and black branch, cutting, hits thin film, dries;
(7) Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve;
(8) Herba Solani Nigri: get crude drug, removing is obstructed always, impurity, cleans, slightly moistens, cutting, dry;
(9) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(10) Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;
(11) Rhizoma Alpiniae Officinarum: pick clean impurity, washing, slightly soaks, pulls out, run through, and section, dries;
(12) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
(13) Flos Citri Sarcodactylis: gather during flower thinning before sunrise in morning, or pickup fallen flowers, dry or dry;
(14) Oletum Trogopterori: pick clean impurity, smashes or sieves dedust bits;
(15) Pseudobulbus Bletillae (Rhizoma Bletillae): pick decontamination, is soaked in water, and pulls out, dries in the air even to inside and outside humidity, and section is dry;
(16) Colla cornus cervi: get crude drug, removing impurity, the used time smashs to pieces or levigation;
(17) Herba Agrimoniae: removing impurity undesirable root, cleans, runs through, cut off, dry;
(18) Radix Linderae: pick decontamination, separately size bar, saturating with blister, changing water according to noting season, preventing smelly, pulling section out in time, sieve dedust bits;
(19) Radix Morindae Officinalis: pick decontamination, after soaking, pumps core while hot, cutting, dry with hot water;
(20) Fructus Amomi: pick decontamination and shell, smash to pieces;
(21) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;
(22) Radix Bupleuri: get crude drug, removes residual stem, impurity, cleans, softens, cut sheet, dry, and sieve removes chip;
(23) Semen Coicis: get crude drug, removing residual cot, impurity;
(24) Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
(25) Radix Et Rhizoma Rhei: get the Radix Et Rhizoma Rhei be cut into small pieces, former medicine picks clean impurity, size stepping, and moistening is even to inside and outside humidity, and section, dries;
(26) Semen Pharbitidis: get crude drug, removing impurity, flat grain and shell, the used time smashs to pieces;
(27) Fructus Chebulae: get crude drug, removing impurity, cleaning, drying;
(28) Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
(29) Fructus Cannabis: pick decontamination and residual shell, get clean core;
(30) Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
(2) prepare
(1) Endoconcha Sepiae after the process of preparing Chinese medicine, Concha Arcae, Bulbus Fritillariae Thunbergii, Radix Cyathulae, Radix Codonopsis, Herba Dendrobii, Fructus Gardeniae, Herba Solani Nigri, the Radix Paeoniae Alba, Fructus Evodiae, Rhizoma Alpiniae Officinarum, Radix Glycyrrhizae, Flos Citri Sarcodactylis, Oletum Trogopterori, Pseudobulbus Bletillae (Rhizoma Bletillae), Colla cornus cervi, Herba Agrimoniae, the Radix Linderae, Radix Morindae Officinalis, Fructus Amomi, Cortex Magnoliae Officinalis, Radix Bupleuri, Semen Coicis, Radix Curcumae, Radix Et Rhizoma Rhei, Semen Pharbitidis, Fructus Chebulae, Cortex Cinnamomi, Fructus Cannabis, Herba Taraxaci are put into decocting container, add water 8 times amount, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring, 4 doses are divided into take.
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105727099A (en) * | 2016-04-27 | 2016-07-06 | 张桂臣 | Traditional Chinese medicine composition for treating peptic ulcer and preparation method thereof |
| CN105770760A (en) * | 2016-04-27 | 2016-07-20 | 张桂臣 | Preparation for treating gastric ulcer and preparation method thereof |
| CN105770761A (en) * | 2016-04-27 | 2016-07-20 | 张桂臣 | Traditional Chinese medicine composition for treating gastric ulcer and preparation method |
| CN105770381A (en) * | 2016-04-27 | 2016-07-20 | 张桂臣 | Preparation taken by patients suffering from gastric ulcers and production method of preparation |
| CN105833131A (en) * | 2016-04-27 | 2016-08-10 | 张桂臣 | Preparation for treating gastric ulcer and duodenal ulcer and preparation method |
| CN105902948A (en) * | 2016-04-27 | 2016-08-31 | 张桂臣 | Preparation for treating chronic gastric ulcer and preparation method of preparation for treating chronic gastric ulcer |
| CN105902766A (en) * | 2016-04-27 | 2016-08-31 | 张桂臣 | Peptic ulcer treating medicine and preparation method thereof |
| CN105920386A (en) * | 2016-04-27 | 2016-09-07 | 张桂臣 | Agent for treating gastric ulcer in imaging department and preparation method of agent |
| CN105920385A (en) * | 2016-04-27 | 2016-09-07 | 张桂臣 | Traditional Chinese medicinal preparation for treating duodenal ulcer in radiology department and preparation method of traditional Chinese medicinal preparation |
| CN105920513A (en) * | 2016-04-27 | 2016-09-07 | 张桂臣 | Preparation for treating duodenal ulcer in laboratory department and preparation method of preparation |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1323599A (en) * | 2000-05-12 | 2001-11-28 | 王绍彬 | Medicine for treating diseases of digestive system |
| CN1546066A (en) * | 2003-09-15 | 2004-11-17 | 史 忠 | Gastrointestinal ulcer treating Chinese traditional medicine |
| CN101537156A (en) * | 2009-01-22 | 2009-09-23 | 曹莹莹 | Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease |
| CN101791388A (en) * | 2010-04-12 | 2010-08-04 | 汤永顺 | Traditional Chinese medicine preparation for treating peptic ulcer |
| CN103182065A (en) * | 2013-03-27 | 2013-07-03 | 朱新华 | Oral liquid for treating gastric and duodenal ulcer efficiently |
-
2015
- 2015-12-12 CN CN201510913424.1A patent/CN105327296A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1323599A (en) * | 2000-05-12 | 2001-11-28 | 王绍彬 | Medicine for treating diseases of digestive system |
| CN1546066A (en) * | 2003-09-15 | 2004-11-17 | 史 忠 | Gastrointestinal ulcer treating Chinese traditional medicine |
| CN101537156A (en) * | 2009-01-22 | 2009-09-23 | 曹莹莹 | Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease |
| CN101791388A (en) * | 2010-04-12 | 2010-08-04 | 汤永顺 | Traditional Chinese medicine preparation for treating peptic ulcer |
| CN103182065A (en) * | 2013-03-27 | 2013-07-03 | 朱新华 | Oral liquid for treating gastric and duodenal ulcer efficiently |
Non-Patent Citations (2)
| Title |
|---|
| 张永平等: "益胃愈疡汤治疗消化性溃疡疗效的临床观察", 《健康必读》 * |
| 黄文曼等: "益胃愈疡汤治疗胃溃疡120例", 《吉林中医药》 * |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105727099A (en) * | 2016-04-27 | 2016-07-06 | 张桂臣 | Traditional Chinese medicine composition for treating peptic ulcer and preparation method thereof |
| CN105770760A (en) * | 2016-04-27 | 2016-07-20 | 张桂臣 | Preparation for treating gastric ulcer and preparation method thereof |
| CN105770761A (en) * | 2016-04-27 | 2016-07-20 | 张桂臣 | Traditional Chinese medicine composition for treating gastric ulcer and preparation method |
| CN105770381A (en) * | 2016-04-27 | 2016-07-20 | 张桂臣 | Preparation taken by patients suffering from gastric ulcers and production method of preparation |
| CN105833131A (en) * | 2016-04-27 | 2016-08-10 | 张桂臣 | Preparation for treating gastric ulcer and duodenal ulcer and preparation method |
| CN105902948A (en) * | 2016-04-27 | 2016-08-31 | 张桂臣 | Preparation for treating chronic gastric ulcer and preparation method of preparation for treating chronic gastric ulcer |
| CN105902766A (en) * | 2016-04-27 | 2016-08-31 | 张桂臣 | Peptic ulcer treating medicine and preparation method thereof |
| CN105920386A (en) * | 2016-04-27 | 2016-09-07 | 张桂臣 | Agent for treating gastric ulcer in imaging department and preparation method of agent |
| CN105920385A (en) * | 2016-04-27 | 2016-09-07 | 张桂臣 | Traditional Chinese medicinal preparation for treating duodenal ulcer in radiology department and preparation method of traditional Chinese medicinal preparation |
| CN105920513A (en) * | 2016-04-27 | 2016-09-07 | 张桂臣 | Preparation for treating duodenal ulcer in laboratory department and preparation method of preparation |
| CN107595937A (en) * | 2017-11-03 | 2018-01-19 | 浙江中医药大学 | A kind of root of three-nerved spicebush composition and its application with antagonism inflammatory bowel disease |
| CN107595937B (en) * | 2017-11-03 | 2021-02-23 | 浙江中医药大学 | Combined spicebush root composition with inflammatory bowel disease antagonism and application thereof |
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Application publication date: 20160217 |