CN103638314A - Medicament for treating thyroid adenoma and preparation method of medicament - Google Patents
Medicament for treating thyroid adenoma and preparation method of medicament Download PDFInfo
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- CN103638314A CN103638314A CN201310670891.7A CN201310670891A CN103638314A CN 103638314 A CN103638314 A CN 103638314A CN 201310670891 A CN201310670891 A CN 201310670891A CN 103638314 A CN103638314 A CN 103638314A
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Abstract
The invention discloses a medicament for treating thyroid adenoma and a preparation method of the medicament. The medicament is mainly prepared from medicines such as artemisia anomala, dutchmanspipe root, bryozoatum, oyster, rhizoma polygonati, Paris polyphylla, concha arcae, radix semiaquilegiae, dicliptera chinensis, blackberry lily, pastinaca sativa, jellyfish and the like according to a certain weight ratio. The medicament disclosed by the invention has the functions of clearing away heat and toxic materials, relieving swelling and pain and activating blood to restore menstrual flow, and is rapid to take an effect and good in curative effect when used for treating thyroid adenoma, and the disease is not easy to reoccur after being healed.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of thyroid adenoma and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Thyroid adenoma is the benign tumor that originates from thyroid follicular cells, is the modal benign tumor of thyroid, is apt to occur in the active stage of thyroid function.Two kinds of the real gonadomas of clinical minute folliculus shape and mamillary, the former is common.Normal is single clear-cut tuberosity in capsula glandulae thyreoideae, has complete peplos, and size is 1～10 centimetre.At present, because Western medicine cannot rapid, effective treatment thyroid adenoma, and long-term taking Western medicine has certain side effect, and therefore, people exist very large demand to the Chinese medicine of rapid, effective treatment thyroid adenoma.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment thyroid adenoma, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat thyroid adenoma.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention is to select Herba Artemisiae Anomalae, Radix Aristolochiae, Pumex, Concha Ostreae, Rhizoma Polygonati, Rhizoma Paridis, Concha Arcae, Radix Semiaquilegiae, Herba Diclipterae Chinensis, Rhizoma Belamcandae, Radix Saposhnikoviae, Rhopilema esculenta, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Platycodonis, Pericarpium Citri Reticulatae Viride, Pseudobulbus cremastrae seu pleiones, Thallus Laminariae (Thallus Eckloniae), Fructus Perillae, Arisaema Cum Bile, Ramulus Euonymi, the Radix Polygoni Multiflori, Semen Vaccariae, Fructus Akebiae, Fructus Rosae Laevigatae, Concha Margaritifera, Semen Pharbitidis, Radix Polygalae, Herba Selaginellae, Radix Gentianae, Radix Rhapontici, Concha Meretricis seu Cyclinae, Bulbus Fritillariae Thunbergii, Squama Manis medicine combines, make each efficacy of drugs produce synergism these drug regimens, thereby recurrence that can fast treating thyroid adenoma.Wherein select Herba Artemisiae Anomalae to be because its nature and flavor are bitter, temperature, enters the heart, spleen channel, has removing blood stasis to stimulate the menstrual flow, and the function of healing up sore and subduing swelling, controls amenorrhea and mass in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, Yong Du burning swelling.Select Radix Aristolochiae to be because its nature and flavor are arduous, cold, enter lung, stomach warp, there is circulation of qi promoting, removing toxic substances, the function of detumescence, controls chest and abdomen swelling and pain, acute filthy disease, enteritis dysentery, hypertension, hernia, Serpentis stings poison, carbuncle, furuncle, skin pruritus or wet rotten.Select Pumex to be because its nature and flavor are salty-cold, enter lung, stomach warp, have lung heat clearing fire, change old expectorant, softening the hard mass, treating stranguria function, controls expectorant dyspnea of heat type and coughs, old accumulation of phlegm piece, goiter, scrofula, hernia, skin ulcer is swollen, corneal nebula.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Rhizoma Polygonati to be because its nature and flavor are sweet flat, enter spleen, lung, kidney channel, have invigorating the spleen and replenishing QI, profit cardiopulmonary, the function of bone and muscle strengthening, controls deficient cold and heat, pulmonary tuberculosis hemoptysis, the empty lack of appetite of body after being ill, muscles and bones is weak, rheumatalgia, wind favus disease.Select Rhizoma Paridis to be because its nature and flavor are bitter, be slightly cold, slightly poisonous, return Liver Channel, there is heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, convulsion with spasms.Select Concha Arcae to be because its nature and flavor are sweet, salty, flat, enter liver, spleen channel, have and reduce phlegm, softening the hard mass, dissipating blood stasis, the function of removing food stagnancy, controls accumulation of phlegm, and stomachache is noisy, acid regurgitation ， mass in the abdomen, scrofula, ulcerative gingivitis.Select Radix Semiaquilegiae to be because its nature and flavor sweetness and bitterness is cold, enter spleen, small intestinal, bladder three warps, have heat clearing away, removing toxic substances, detumescence, eliminating stagnation, the function of diuresis, controls carbuncle, scrofula, furuncle, stranguria with turbid discharge, leukorrhagia, cough due to deficiency of the lung, hernia ， epilepsy, infantile convulsion, hemorrhoid, traumatic injury.Select Herba Diclipterae Chinensis to be because its nature and flavor are bitter, cold, there is heat clearing away, removing heat from blood, diuresis, the function of removing toxic substances, controls calentura macule, has blood in stool, hematuria, dysuria, toxic swelling furuncle.Select Rhizoma Belamcandae to be because its nature and flavor are bitter, cold, poisonous, enter lung, Liver Channel, there is pathogenic fire reducing, removing toxic substances, loose blood, the function of expectorant, controls sore throat pharyngalgia, cough with dyspnea, accumulation and obstruction of sputum, scrofula tuberculosis, malaria with splenomegaly, women's amenorrhea, carbuncle sore tumefacting virus.Selecting Radix Saposhnikoviae is that temperature, enters bladder, lung, spleen channel, delivers because of its property acrid-sweet flavor, dispels the wind, and victory is wet, and the function of pain relieving, controls affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, and anemofrigid-damp arthralgia, joint is ached, and extremity contraction is anxious, tetanus.Select Rhopilema esculenta to be because its nature and flavor are salty, flat, enter liver, kidney channel, there is heat clearing away, reduce phlegm, removing food stagnancy, the function of intestine moistening, controls cough, asthma, mass in the abdomen distension, constipation due to dry stool, swelling of the feet, sucutaneous nodule.Select Herba Hedyotidis Diffusae to be because its property bitter but sweet flavor is cold, enter the heart, liver, spleen three warps, have heat clearing away, dampness removing, the function of removing toxic substances, controls dyspnea and cough due to lung-heat, tonsillitis, pharyngolaryngitis, appendicitis, dysentery, jaundice, pelvic inflammatory disease, adnexitis, carbuncle furuncle, venom.Select Herba Scutellariae Barbatae to be because its nature and flavor are bitter, cold, there is heat clearing away, the function of removing toxic substances, controls laryngopharynx swelling and pain, scalds traumatic injury, eczema.Select Radix Platycodonis to be because its nature and flavor toil is flat, enter lung, stomach warp, have out lung qi dispersing gas, the function of the evacuation of pus of eliminating the phlegm, controls exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Selecting Pericarpium Citri Reticulatae Viride is that tepor, enters liver, gallbladder meridian, has soothing the liver dispelling the stagnated QI because of its nature and flavor toil, and the function of eliminating stagnation expectorant is controlled breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction piece.Select Pseudobulbus cremastrae seu pleiones to be because its nature and flavor are sweet micro-pungent, cold, enter liver, spleen channel, there is detumescence, eliminating stagnation, reduces phlegm, and the function of removing toxic substances is controlled carbuncle furuncle swollen, scrofula, sore throat swells and ache, Serpentis, worm, mad dog wound.Select Thallus Laminariae (Thallus Eckloniae) to be because its nature and flavor are salty, cold, enter stomach warp, there is softening the hard mass, the function of row water, controls scrofula, and goiter is dysphagic, edema, painful and swollen testis, leukorrhagia.Select Fructus Perillae to be because its nature and flavor are pungent, temperature, enters lung, large intestine channel, has the therapeutic method to keep the adverse QI flowing downwards, expectorant, and lung moistening, the function of wide intestinal, controls cough with dyspnea, phlegm dyspnea, the stagnation of QI, constipation.Select Arisaema Cum Bile to be because its nature and flavor are bitter, cool in nature, enter the heart, liver, lung three warps, have clearing away fire and eliminating phlegm, the relieving convulsion Epilepsy of Dinging, phlegm-fire is breathed heavily and is coughed, phlegm-accumulating vertigo.Select Ramulus Euonymi to be because its nature and flavor are bitter, cold, enter meridian of Foot-JUE YIN, there is removing blood stasis, to stimulate the menstrual flow, the function of parasite killing, controls amenorrhea ， mass in the abdomen, and puerperal, stasis of blood band was suffered from abdominal pain, abdominal pain due to worm stagnation.Select Radix Polygoni Multiflori to be because its property bitter but sweet flavor is puckery, tepor, enters liver, kidney channel, has tonifying liver, and kidney tonifying, nourishes blood, the function of dispeling the wind, control hepatic and renal YIN deficiency, sending out must be early white, and blood deficiency is dizzy, and waist knee joint is weak, and muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Select Semen Vaccariae to be because its nature and flavor are bitter flat, enter liver, stomach warp, have promoting the circulation of blood to stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, the function of detumescence sore, controls women's amenorrhea, galactostasis, and difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.Select Fructus Akebiae to be because its nature and flavor are sweet, cold, there is liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, the function of relieving restlessness diuresis, treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, dysentery, lumbago, hypochondriac pain, hernia, dysmenorrhea, uterus tenesmus.Select Fructus Rosae Laevigatae to be because its nature and flavor are sour and astringent, flat, there is reinforcing the kidney and controlling nocturnal emission, the function of reducing urination and antidiarrheal, controls spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery.Select Concha Margaritifera to be because its nature and flavor are salty, cool, enter the heart, liver two warps, have suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, the function of hemostasis, controls dizziness, tinnitus, cardiopalmus, insomnia, demented ， Jing Epilepsy, spits blood, epistaxis, metrorrhagia.Select Semen Pharbitidis to be because its nature and flavor are bitter, cold, poisonous, return lung, kidney, large intestine channel, there is removing water retention by purgation relieving constipation, drink is washed in expectorant, and parasite killing is attacked long-pending function, the swelling pain of harnessing the river, constipation and anuresis, phlegm retention is gathered, and QI rising in reverse order is breathed with cough, abdominal pain due to worm stagnation, ascarid, taeniasis.Selecting Radix Polygalae is that temperature, enters the heart, kidney channel, has the Fructus Alpiniae Oxyphyllae of calming the nerves, and eliminates the phlegm because of its nature and flavor toil, and the function of resolving depression, controls palpitation with fear, forgetful, nocturnal emission, and insomnia, cough ant phlegm, carbuncle skin ulcer is swollen.Select Herba Selaginellae to be because its nature and flavor are pungent, flat, enter that foot is fainted, few cloudy blood system, have removing blood stasis, fry the function with hemostasis, raw with controlling amenorrhea ， mass in the abdomen, traumatic injury, suffers from abdominal pain, asthma, and parch to black, with controlling haematemesis, is had blood in stool, hematuria, proctoptosis.Select Radix Gentianae to be because its nature and flavor are bitter, cold, enter liver, gallbladder meridian, there is eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.Select Radix Rhapontici to be because its nature and flavor hardship is salty-cold, enter stomach, large intestine channel, have heat-clearing and toxic substances removing, the function of stimulating milk secretion, controls the swollen pain of breast, galactostasis, toxic-heat and blood stasis, arthralgia.Select Concha Meretricis seu Cyclinae to be because its nature and flavor are salty, flat, enter brothers' sun, Yangming Channel, there is heat clearing away, diuretic, reduces phlegm, and the function of softening the hard mass is controlled heat-phlegm and is breathed heavily and cough, edema, gonorrhea, wart, tumor, gather, blood agglomeration chest pain, dysentery, hemorrhoid, metrorrhagia, leukorrhagia.Select Bulbus Fritillariae Thunbergii to be because its nature and flavor are bitter, be slightly cold, return lung, heart channel, have heat clearing away eliminating stagnation, the function of preventing phlegm from forming and stopping coughing, controls wind-heat invading the lung, phlegm-fire cough, and lung abscess, acute mastitis, scrofula, sore, ambition is gloomy.Select Squama Manis to be because its nature and flavor are salty, cool, enter liver, stomach warp, have the routed carbuncle of detumescence, search wind active, the function of the stimulating milk secretion of stimulating the menstrual flow, controls carbuncle skin ulcer swollen, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external hemostasis.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Herba Artemisiae Anomalae 10-20 gram of Radix Aristolochiae 10-20 gram of Pumex 25-35 gram
Concha Ostreae 10-20 gram of Rhizoma Polygonati 5-15 grammes per square metre building 10-20 gram
Concha Arcae 25-35 gram of Radix Semiaquilegiae 15-25 gram of Herba Diclipterae Chinensis 25-35 gram
Rhizoma Belamcandae 25-35 gram of Radix Saposhnikoviae 5-15 gram of Rhopilema esculenta 5-15 gram
Herba Hedyotidis Diffusae 10-20 gram of Herba Scutellariae Barbatae 5-15 gram of Radix Platycodonis 5-15 gram
25-35 gram of Thallus Laminariae (Thallus Eckloniae) 10-20 gram of Pericarpium Citri Reticulatae Viride 5-15 Keshan Rhizoma sagittariae sagittifoliae
Fructus Perillae 15-25 gram of Arisaema Cum Bile 5-15 gram of Ramulus Euonymi 10-20 gram
Radix Polygoni Multiflori 5-15 gram of Semen Vaccariae 5-15 gram of Fructus Akebiae 15-25 gram
Fructus Rosae Laevigatae 10-20 gram of Concha Margaritifera 10-20 gram of Semen Pharbitidis 5-15 gram
Radix Polygalae 15-25 gram of Herba Selaginellae 5-15 cron gallbladder 10-20 gram
Radix Rhapontici 5-15 gram of Concha Meretricis seu Cyclinae 5-15 gram of Bulbus Fritillariae Thunbergii 25-35 gram
Squama Manis 3-9 gram
Preferable amount is
30 grams of 15 grams of Pumexs of 15 grams of Radix Aristolochiaes of Herba Artemisiae Anomalae
15 grams, 15 grams of Rhizoma Polygonatis of Concha Ostreae, 10 grammes per square metre building
30 grams of 20 grams of Herba Diclipterae Chinensis of 30 grams of Radix Semiaquilegiaes of Concha Arcae
10 grams of 10 grams of Rhopilema esculentas of 30 grams of Radix Saposhnikoviaes of Rhizoma Belamcandae
10 grams of 10 grams of Radix Platycodoniss of 15 grams of Herba Scutellariae Barbataes of Herba Hedyotidis Diffusae
15 grams of 30 grams of Thallus Laminariae (Thallus Eckloniae)s of Pericarpium Citri Reticulatae Viride 10 Keshan Rhizoma sagittariae sagittifoliae
15 grams of 10 grams of Ramulus Euonymis of 20 grams of Arisaema Cum Bile of Fructus Perillae
20 grams of 10 grams of Fructus Akebiaes of 10 grams of Semen Vaccariae of the Radix Polygoni Multiflori
10 grams of 15 grams of Semen Pharbitidiss of 15 grams of Concha Margaritiferas of Fructus Rosae Laevigatae
15 grams, 20 grams of Herba Selaginellaes of Radix Polygalae, 10 cron gallbladder
30 grams of 10 grams of Bulbus Fritillariae Thunbergiis of 10 grams of Concha Meretricis seu Cyclinaes of Radix Rhapontici
6 grams of Squama Maniss
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Herba Artemisiae Anomalae: choose clean impurity, remove root, water edulcoration, slightly soaks, and cutting is dried;
2, Radix Aristolochiae: choose decontamination, separately size bar, is soaked in water, and pulls out, and profit is even to inside and outside humidity, section is dry;
3, Pumex: clean and dry, smash;
4, Concha Ostreae: clean, dry, smash use;
5, Rhizoma Polygonati: clean earth, slightly profit, cuts into slices, and dries;
6, Rhizoma Paridis: remove fibrous root, cleaning, drying;
7, Concha Arcae: clean and dry, smash;
8, Radix Semiaquilegiae: clear water is cleaned, section, dries;
9, Herba Diclipterae Chinensis: summer, autumn gather, dries, or gets fresh grass and use;
10, Rhizoma Belamcandae: choose decontamination, water is cleaned, and slightly soaks, and pulls out, runs through, and section, dries, sieve removes palpus, bits;
11, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
12, Rhopilema esculenta: enter in clear water and soak and float, often change water, Ex-all saline taste and sand, chopping is used;
13, Herba Hedyotidis Diffusae: get crude drug, remove impurity, wash quickly is clean, slightly dries in the air, and cutting is dry, sieve dedust bits;
14, Herba Scutellariae Barbatae: remove impurity, clean, slightly moisten, cutting, dry;
15, Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;
16, Pericarpium Citri Reticulatae Viride: choose clean impurity, be soaked in water, pull out, run through, section, dries;
17, Pseudobulbus cremastrae seu pleiones: eliminate fibrous root, clean, clear water soaks 2-4 hour, and taking-up runs through, and section, dries;
18, Thallus Laminariae (Thallus Eckloniae): choose decontamination, water rinses, is cut into wide silk, dries;
19, Fructus Perillae: the dedust of winnowing with a dustpan bits, clean, dry;
20, Arisaema Cum Bile: get crude drug, choose decontamination;
21, Ramulus Euonymi: choose decontamination, by water saturates, pull out, cutting, dries;
22, Radix Polygoni Multiflori: choose decontamination, clean, saturating with blister to eighty per cant, to pull out, profit is even to inside and outside humidity, and section or dice, dry;
23, Semen Vaccariae: the clean impurity of winnowing with a dustpan, put in pot, while spending six, seventy percent with slow fire stir-fry in vain to popping, take out, cool;
24, Fructus Akebiae: clean, slightly soak, moistening is to saturating, and section is dried, or cleans and dry, and the used time smashs to pieces;
25, Fructus Rosae Laevigatae: choose decontamination, cut two lobes, water slightly soaks, and pulls out, removes residual burr after moistening, digs clean hair, core, dry;
26, Concha Margaritifera: choose decontamination, knock fragment, sieve dedust bits;
27, Semen Pharbitidis: get crude drug, remove impurity, flat grain and shell, the used time smashs to pieces;
28, Radix Polygalae: choose decontamination, cutting, sieve dedust bits;
29, Herba Selaginellae charcoal: get clean Herba Selaginellae, put in pot and fry to outer performance coke black with high heat, be inside coke yellow, spray clear water, takes out, and dries;
30, Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
31, Radix Rhapontici: choose clean impurity, unhairing is cleaned, and runs through, and section, dries;
32, Concha Meretricis seu Cyclinae: clean, dry, be ground into fragment;
33, Bulbus Fritillariae Thunbergii: remove impurity, big or small stepping, cleans, and runs through, and cuts sheet, and dry, chip is removed in street, or smashes;
34, Squama Manis: get the Squama Manis sheet of choosing clean, separately size, separately puts sand in pot and make popular, adds Squama Manis sheet, fries to heaving while being golden yellow, takes out, and sieve shakeout, cools.
Two, preparation
1, by the Herba Artemisiae Anomalae of described weight, Radix Aristolochiae, Pumex, Concha Ostreae, Rhizoma Polygonati, Rhizoma Paridis, Concha Arcae, Radix Semiaquilegiae, Herba Diclipterae Chinensis, Rhizoma Belamcandae, Radix Saposhnikoviae, Rhopilema esculenta, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Platycodonis, Pericarpium Citri Reticulatae Viride, Pseudobulbus cremastrae seu pleiones, Thallus Laminariae (Thallus Eckloniae), Fructus Perillae, Arisaema Cum Bile, Ramulus Euonymi, the Radix Polygoni Multiflori, Semen Vaccariae, Fructus Akebiae, Fructus Rosae Laevigatae, Concha Margaritifera, Semen Pharbitidis, Radix Polygalae, Herba Selaginellae, Radix Gentianae, Radix Rhapontici, Concha Meretricis seu Cyclinae, Bulbus Fritillariae Thunbergii, Squama Manis medicine decocts with water secondary, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 35 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.
2, the medicinal residues after filtering are for the first time added to 6 times of amounts of water, decoct boiling, then use slow fire boiling 30 minutes, filter to obtain decoction liquor for the second time.
3, twice decoction liquor mixed, intense fire boils, then with slow fire boiling 10 minutes and get final product, decoction liquor is divided into 6 doses and takes.
Medicine of the present invention has heat-clearing and toxic substances removing, reducing swelling and alleviating pain, and the effect that promoting the circulation of blood is stimulated the menstrual flow, treatment thyroid adenoma instant effect, short treating period, do not recur.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 175 examples for medical treatment.
2, diagnostic criteria
Patient mostly is women, and the age was everlasting below 40 years old, is generally the single-shot tuberosity in thyroid body.The course of disease is slow, most several months to the several years even the time longer, patient finds or is found the cervical region thing that swells without any symptom because of slightly uncomfortable.Majority is single-shot, circular or oval, smooth surface, and clear border, the tough reality of quality,,, can move up and down with swallowing without tenderness without adhesion with surrounding tissue.Diameter of tumor is generally at several centimetres, and huge person is rare.Huge tumor mass can produce adjacent organs pressurized sign, but does not invade these organs.Have small number of patients to know from experience suddenly and increase because of Intratumoral hemorrhage tumor, companion's distending pain, as mamillary capsule gonadoma; Some lump can absorb gradually and dwindle; Can there is cystis degeneration in some.Medical history is compared with elder, often because calcification makes tumor body hard; Some can develop into functional autonomy adenoma, and causes hyperthyroidism.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day, early, middle and late respectively clothes 1 time, 10 days was a course for the treatment of, took continuously 9 courses for the treatment of.
4, efficacy assessment standard
Effective: thyroid adenoma is eliminated, and physical recovery is normal, observe after half a year without recurrence;
Take a turn for the better: thyroid adenoma symptom is clearly better, and body constitution recovers gradually;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy thyroid adenoma patient of the present invention 175 examples, effective 167 examples of result, obvious effective rate is 95.43%, 5 examples that take a turn for the better, and improvement rate is 2.86%, invalid 3 examples, total effective rate is 98.29%.
Claims (3)
1. a medicine for the treatment of thyroid adenoma, is characterized in that: it is to be made by the crude drug in following weight range:
Herba Artemisiae Anomalae 10-20 gram of Radix Aristolochiae 10-20 gram of Pumex 25-35 gram
Concha Ostreae 10-20 gram of Rhizoma Polygonati 5-15 grammes per square metre building 10-20 gram
Concha Arcae 25-35 gram of Radix Semiaquilegiae 15-25 gram of Herba Diclipterae Chinensis 25-35 gram
Rhizoma Belamcandae 25-35 gram of Radix Saposhnikoviae 5-15 gram of Rhopilema esculenta 5-15 gram
Herba Hedyotidis Diffusae 10-20 gram of Herba Scutellariae Barbatae 5-15 gram of Radix Platycodonis 5-15 gram
25-35 gram of Thallus Laminariae (Thallus Eckloniae) 10-20 gram of Pericarpium Citri Reticulatae Viride 5-15 Keshan Rhizoma sagittariae sagittifoliae
Fructus Perillae 15-25 gram of Arisaema Cum Bile 5-15 gram of Ramulus Euonymi 10-20 gram
Radix Polygoni Multiflori 5-15 gram of Semen Vaccariae 5-15 gram of Fructus Akebiae 15-25 gram
Fructus Rosae Laevigatae 10-20 gram of Concha Margaritifera 10-20 gram of Semen Pharbitidis 5-15 gram
Radix Polygalae 15-25 gram of Herba Selaginellae 5-15 cron gallbladder 10-20 gram
Radix Rhapontici 5-15 gram of Concha Meretricis seu Cyclinae 5-15 gram of Bulbus Fritillariae Thunbergii 25-35 gram
Squama Manis 3-9 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
30 grams of 15 grams of Pumexs of 15 grams of Radix Aristolochiaes of Herba Artemisiae Anomalae
15 grams, 15 grams of Rhizoma Polygonatis of Concha Ostreae, 10 grammes per square metre building
30 grams of 20 grams of Herba Diclipterae Chinensis of 30 grams of Radix Semiaquilegiaes of Concha Arcae
10 grams of 10 grams of Rhopilema esculentas of 30 grams of Radix Saposhnikoviaes of Rhizoma Belamcandae
10 grams of 10 grams of Radix Platycodoniss of 15 grams of Herba Scutellariae Barbataes of Herba Hedyotidis Diffusae
15 grams of 30 grams of Thallus Laminariae (Thallus Eckloniae)s of Pericarpium Citri Reticulatae Viride 10 Keshan Rhizoma sagittariae sagittifoliae
15 grams of 10 grams of Ramulus Euonymis of 20 grams of Arisaema Cum Bile of Fructus Perillae
20 grams of 10 grams of Fructus Akebiaes of 10 grams of Semen Vaccariae of the Radix Polygoni Multiflori
10 grams of 15 grams of Semen Pharbitidiss of 15 grams of Concha Margaritiferas of Fructus Rosae Laevigatae
15 grams, 20 grams of Herba Selaginellaes of Radix Polygalae, 10 cron gallbladder
30 grams of 10 grams of Bulbus Fritillariae Thunbergiis of 10 grams of Concha Meretricis seu Cyclinaes of Radix Rhapontici
6 grams of Squama Maniss.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Herba Artemisiae Anomalae: choose clean impurity, remove root, water edulcoration, slightly soaks, and cutting is dried;
(2) Radix Aristolochiae: choose decontamination, separately size bar, is soaked in water, and pulls out, and profit is even to inside and outside humidity, section is dry;
(3) Pumex: clean and dry, smash;
(4) Concha Ostreae: clean, dry, smash use;
(5) Rhizoma Polygonati: clean earth, slightly profit, cuts into slices, and dries;
(6) Rhizoma Paridis: remove fibrous root, cleaning, drying;
(7) Concha Arcae: clean and dry, smash;
(8) Radix Semiaquilegiae: clear water is cleaned, section, dries;
(9) Herba Diclipterae Chinensis: summer, autumn gather, dries, or gets fresh grass and use;
(10) Rhizoma Belamcandae: choose decontamination, water is cleaned, and slightly soaks, and pulls out, runs through, and section, dries, sieve removes palpus, bits;
(11) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(12) Rhopilema esculenta: enter in clear water and soak and float, often change water, Ex-all saline taste and sand, chopping is used;
(13) Herba Hedyotidis Diffusae: get crude drug, remove impurity, wash quickly is clean, slightly dries in the air, and cutting is dry, sieve dedust bits;
(14) Herba Scutellariae Barbatae: remove impurity, clean, slightly moisten, cutting, dry;
(15) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;
(16) Pericarpium Citri Reticulatae Viride: choose clean impurity, be soaked in water, pull out, run through, section, dries;
(17) Pseudobulbus cremastrae seu pleiones: eliminate fibrous root, clean, clear water soaks 2-4 hour, and taking-up runs through, and section, dries;
(18) Thallus Laminariae (Thallus Eckloniae): choose decontamination, water rinses, is cut into wide silk, dries;
(19) Fructus Perillae: the dedust of winnowing with a dustpan bits, clean, dry;
(20) Arisaema Cum Bile: get crude drug, choose decontamination;
(21) Ramulus Euonymi: choose decontamination, by water saturates, pull out, cutting, dries;
(22) Radix Polygoni Multiflori: choose decontamination, clean, saturating with blister to eighty per cant, to pull out, profit is even to inside and outside humidity, and section or dice, dry;
(23) Semen Vaccariae: the clean impurity of winnowing with a dustpan, put in pot, while spending six, seventy percent with slow fire stir-fry in vain to popping, take out, cool;
(24) Fructus Akebiae: clean, slightly soak, moistening is to saturating, and section is dried, or cleans and dry, and the used time smashs to pieces;
(25) Fructus Rosae Laevigatae: choose decontamination, cut two lobes, water slightly soaks, and pulls out, removes residual burr after moistening, digs clean hair, core, dry;
(26) Concha Margaritifera: choose decontamination, knock fragment, sieve dedust bits;
(27) Semen Pharbitidis: get crude drug, remove impurity, flat grain and shell, the used time smashs to pieces;
(28) Radix Polygalae: choose decontamination, cutting, sieve dedust bits;
(29) Herba Selaginellae charcoal: get clean Herba Selaginellae, put in pot and fry to outer performance coke black with high heat, be inside coke yellow, spray clear water, takes out, and dries;
(30) Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
(31) Radix Rhapontici: choose clean impurity, unhairing is cleaned, and runs through, and section, dries;
(32) Concha Meretricis seu Cyclinae: clean, dry, be ground into fragment;
(33) Bulbus Fritillariae Thunbergii: remove impurity, big or small stepping, cleans, and runs through, and cuts sheet, and dry, chip is removed in street, or smashes;
(34) Squama Manis: get the Squama Manis sheet of choosing clean, separately size, separately puts sand in pot and make popular, adds Squama Manis sheet, fries to heaving while being golden yellow, takes out, and sieve shakeout, cools;
(2) preparation
(1) by the Herba Artemisiae Anomalae of described weight, Radix Aristolochiae, Pumex, Concha Ostreae, Rhizoma Polygonati, Rhizoma Paridis, Concha Arcae, Radix Semiaquilegiae, Herba Diclipterae Chinensis, Rhizoma Belamcandae, Radix Saposhnikoviae, Rhopilema esculenta, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Radix Platycodonis, Pericarpium Citri Reticulatae Viride, Pseudobulbus cremastrae seu pleiones, Thallus Laminariae (Thallus Eckloniae), Fructus Perillae, Arisaema Cum Bile, Ramulus Euonymi, the Radix Polygoni Multiflori, Semen Vaccariae, Fructus Akebiae, Fructus Rosae Laevigatae, Concha Margaritifera, Semen Pharbitidis, Radix Polygalae, Herba Selaginellae, Radix Gentianae, Radix Rhapontici, Concha Meretricis seu Cyclinae, Bulbus Fritillariae Thunbergii, Squama Manis medicine decocts with water secondary, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 35 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time,
(2) medicinal residues after filtering are for the first time added to 6 times of amounts of water, decoct boiling, then use slow fire boiling 30 minutes, filter to obtain decoction liquor for the second time;
(3) twice decoction liquor mixed, intense fire boils, then with slow fire boiling 10 minutes and get final product.
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