CN108371703A - A kind of drug and preparation method thereof for treating cervical carcinoma - Google Patents
A kind of drug and preparation method thereof for treating cervical carcinoma Download PDFInfo
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- CN108371703A CN108371703A CN201810522146.0A CN201810522146A CN108371703A CN 108371703 A CN108371703 A CN 108371703A CN 201810522146 A CN201810522146 A CN 201810522146A CN 108371703 A CN108371703 A CN 108371703A
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Abstract
The invention discloses a kind of drugs and preparation method thereof for treating cervical carcinoma, it is mainly by Patrinia scaniosaefolia, cassia twig, trigone, oldenlandia diffusa, wartwort, Radix Astragali, scorpio, the stem of noble dendrobium, curcuma zedoary, the root bark of white mulberry, setose thistle, Cortex Phellodendri, subprostrate sophora, Snakegourd Fruit, madder, jujube, ginseng, Radix Angelicae Sinensis, Chinese blister beetle, rhizoma alismatis, plantain seed, dianthus superbus, caulis lonicerae, blood clam, pivot stores, Fructus Forsythiae, bulbus fritillariae cirrhosae, green peel, myrobalan, rhizome of cyrtomium, dogwood fruit is prepared according to a certain weight ratio, drug of the present invention has clearing heat and detoxicating, apocenosis broken stasis of blood, blood-breaking, nourishing yin and lessening fire, soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm, it is quick for treating cervical carcinoma, good effect, it does not recur.
Description
Technical field
The present invention relates to a kind of drugs and preparation method thereof for treating cervical carcinoma, belong to the field of Chinese medicines.
Technical background
Cervical carcinoma is the gynecological cancer of the currently the only clear cause of disease, and the cause of disease, which is high-risk HPV persistent viral infection, to be caused,
One of an important factor for having substantial connection, women that sexual behaviour early occurs very much with sexual life, being increase cervical cancer pathogenesis rate;If again
Do not notice that sex hygiene or sexual life are unclean, more sex partners etc. can increase the incidence of cervical carcinoma.Chinese medicine then think cervical carcinoma with
Stagnation of QI due to depression of the liver, damp and hot to accumulate poison, the deficiency of liver-yin and kidney-yin, the sinking of qi of middle-jiao related.Since western medicine side effect is big, people are to effectively controlling
There are great demands for the Chinese medicine for the treatment of cervical carcinoma, up to now, it has not been found that the related report about the present invention.
Invention content
Repeatedly verification of the present inventor according to research and the clinical test of theory of traditional Chinese medical science has finally found effectively treatment uterine neck
The drug of cancer, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine compositions of effective treatment cervical carcinoma.
Another aim of the present invention is to provide the preparation methods of the Chinese medicine composition.
The present invention is selection Patrinia scaniosaefolia, cassia twig, trigone, oldenlandia diffusa, wartwort, Radix Astragali, scorpio, the stem of noble dendrobium, curcuma zedoary, Sang Bai
Skin, setose thistle, Cortex Phellodendri, subprostrate sophora, Snakegourd Fruit, madder, jujube, ginseng, Radix Angelicae Sinensis, Chinese blister beetle, rhizoma alismatis, plantain seed, dianthus superbus, caulis lonicerae, watt
Stupefied sub-, pivots storage, Fructus Forsythiae, bulbus fritillariae cirrhosae, green peel, myrobalan, rhizome of cyrtomium, dogwood fruit, the root bark of Chinese wolf-berry, tortoise version, fruit of Chinese wolfberry drug are combined system
Standby, make each efficacy of drugs generate synergistic effect these pharmaceutical compositions, so as to effectively treat cervical carcinoma.Wherein select
Patrinia scaniosaefolia is to put down because its is bitter in taste, enter liver, stomach, large intestine channel, there is clearing heat and detoxicating, the function of apocenosis broken stasis of blood, control acute appendicitis, diarrhea is red
Under leukorrhea, postpartum stasis of blood, red eye, swell pain, carbuncle swells mange.Select cassia twig be because of the pungent sweet, warm of its nature and flavor, enter bladder, the heart,
Lung channel has sweating expelling pathogenic factors from muscles and skin, the function of warming meridians and promoting circulation of qi to control exterior syndrome due to wind-cold, and shoulder carries on the back podomere ache, obstruction of qi in the chest phlegm and retained fluid, Jing Bi Disorder lumps in the abdomen.It selects
Trigone is put down, enters liver, the spleen channel because of its nature and flavor toil, there is a blood-breaking, promoting the circulation of qi, disperse accumulation, and the function of analgesic controls lumps in the chest and abdomen, qi and blood
Solidifying band, trusted subordinate's pain, swollen pain under the side of body, Amenorrhea, postpartum blood stasis abdominal pain, traumatic injury, sore swells are hard.Select oldenlandia diffusa be because
It for its nature and flavor bitter sweet, trembles with fear, enters the heart, liver, spleen three and pass through, there is heat-clearing, dampness removing, the function of removing toxic substances to control dyspnea and cough due to lung-heat, tonsillitis, pharynx
Laryngitis, appendicitis, dysentery, jaundice, pelvic infecton, adnexitis, carbuncle swells furunculosis, venomous snake bite.It is because its nature and flavor is pungent to select wartwort
Hardship, it is cool, it is toxic, enter large and small intestines, spleen has row water, a dissolving phlegm, desinsection, the function of removing toxic substances, controls edematous asthma, sputum cough, malaria,
Scrofula, tinea sore, Tuberculous impotence pipe, osteomyelitis.It is the tepor because its nature and flavor is sweet to select Radix Astragali, enters lung, the spleen channel, raw to be defended with beneficial
Gu table, inducing diuresis for removing edema, eliminating toxic, the function of myogenic control spontaneous perspiration, night sweat, blood-arthralgia, edema, un-festering of ulcer or prolonged fester before gathering；Toast is with there is benefit
The function of middle benefit controls internal injury overstrain, and splenasthenic diarrhea, rectal prolapse, deficiency of vital energy blood is de-, collapses band and the disease of all laboured breathing deficiency of blood.Select scorpio
It is to be put down because its nature and flavor is salty pungent, it is toxic, enter meridian of Foot-JUE YIN, has wind-dispelling, relieving convulsion, dredging collateral, the function of removing toxic substances controls convulsion, insane
Epilepsy, apoplexy, hemiplegia, deviation of the eye and mouth, migraine, arthralgia pain due to rheumatism, lockjaw, scrofula, rubella sore swells.Select the stem of noble dendrobium
It is to tremble with fear because its property slightly sweet flavor is micro- salty, enter to have, lung, kidney channel, have the beneficial stomach that promotes the production of body fluid, the function of clearing heat and nourishing yin to control consumption of body fluid caused by febrile disease, mouth
Dry tired to drink, abnormal heat, impairment of yin mesh are dark after being ill.It is because its nature and flavor is pungent, bitter to select curcuma zedoary, and temperature, Return liver, the spleen channel have promoting the circulation of qi blood-breaking, disappear
The function , Zhi abdominal mass and lump of product analgesic, blood stasis closed, dyspepsia anus pain, treating swelling and pain by traumatic injury, early cervical carcinoma.Select the root bark of white mulberry be because
It is sweet for its nature and flavor, it trembles with fear, enters lung, the spleen channel, there is removing heat from lung and relieving asthma, the function of line water detumescence to control dyspnea and cough due to lung-heat, spit blood, oedema, tinea pedis,
Difficult urination.It selects setose thistle and is because its nature and flavor is sweet, it is cool, enter liver, the spleen channel, there is cool blood, stops blooding, dissolving stasis, the function of subduing inflammation controls
It spits blood, bleeding from five sense organs or subcutaneous tissue, hematuria, blood strangury, metrorrhagia, under, intestines wind, acute appendicitis, large carbuncle pyogenic infections, furunculosis.Select Cortex Phellodendri be because its is bitter in taste,
It is cold, enter lung, stomach, kidney channel, there is nourishing yin and lessening fire, the function of moisturize laxation to control dysphoria with smothery sensation and quench one's thirst, hectic fever due to yin labor heat, cough with lung heat defecates dry
Knot, difficult urination.Selecting subprostrate sophora is trembled with fear because its is bitter in taste, is entered the heart, lung, large intestine three and is passed through, relieves inflammation or internal heat, detoxify, detumescence, only
The function of pain controls retropharyngeal abscess, and sore-throat, larynx numbness, swelling and aching of gum, the full heat-syndrome cough of asthma, jaundice, diarrhea, haemorrhoids, heat is swollen, the favus of the scalp, mange, snake,
Worm, dog bite.Selecting Snakegourd Fruit is trembled with fear because its nature and flavor is sweet, slight bitter, return lung, stomach, large intestine channel, there is a clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens,
The function of moisturize laxation controls cough with lung heat, and the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, acute appendicitis, constipation.It selects
Madder is to tremble with fear because its is bitter in taste, have cooling blood and hemostasis, the function of Stasis through to control haematemesis, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, traumatic hemorrhage, the stasis of blood
Hinder Amenorrhea, joint pain, tumbling and swelling.It is to enter spleen, stomach because of its nature and flavor sweet, warm, there is tonifying spleen and stomach, QI invigorating to select jujube
It promotes the production of body fluid, battalion is adjusted to defend, the function of antidote poison controls stomach void deficiency of food, and the weak loose stool of spleen, qi-blood-body fluid is insufficient, disharmony between ying and wei, palpitation and severe palpitation,
Hysteria of womam.It is to enter spleen, lung channel because of the sweet micro- sweet, warm of its nature and flavor, reinforce vital energy to select ginseng, prevent prolapse and engender liquid, the work(of tranquilizing the mind
Can, it is deficient to control internal lesion caused by overexertion, deficiency of food, burnout, regurgitation and emesis, lingering diarrhea of defecating, cough of deficient and syndrome characterized by dyspnea, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness head
Bitterly, impotence, frequent micturition are quenched one's thirst, woman uterine bleeding, infantile chronic fright and perennial and irrecoverable weakness, the disease of all qi-blood-body fluid deficiencies.Selecting Radix Angelicae Sinensis is
Because its nature and flavor sweet, acrid, warm, enters the heart, liver, the spleen channel, there are benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, the function of moisturize laxation to control irregular menstruation,
Amenorrhea abdominal pain , Disorder lump in the abdomen knots are poly-, uterine bleeding, headache due to deficiency of blood, dizziness, Impotence numbness, and intestinal dryness difficulty just, fall after dysentery characterized by blood in the stool by weight, ulcer sores, metal-inflicted wound
Flutter damage.Selecting Chinese blister beetle is trembled with fear because its nature and flavor is pungent, toxic, is entered large intestine, small intestine, liver and kidney channel, is attacked poison, by the function of the stasis of blood,
Malignant sore is controlled in external application, and first tinea, Kou Yan crooked are oblique, tonsillitis；Internal treatment of scrofula, lyssodexis.Selecting rhizoma alismatis is trembled with fear because its nature and flavor is sweet,
Entering bladder warp, advantageous water, excreting dampness, the function of expelling the heat-evil controls difficult urination, and oedema anus is full, vomiting, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea,
Hematuria.It is to tremble with fear because its nature and flavor is sweet, enter kidney, bladder warp to select plantain seed, advantageous water, heat-clearing, improving eyesight, and the function of eliminating the phlegm is controlled small
Just obstructed, stranguria with turbid discharge, under band, hematuria, summer-heat and damp rush down dysentery, cough ant phlegm, arthritis with fixed pain caused by dampness, hot eyes hides from view.Select dianthus superbus be because its is bitter in taste,
It is cold, enter the heart, kidney, small intestine, bladder warp, there is clearing away heat and promoting diuresis, the function of blood-breaking promoting menstruation to control urinary obstruction, gonorrhoea, oedema, Amenorrhea, carbuncle
Swollen, hot eyes is hidden from view, sore of contaminating.It is to tremble with fear because its nature and flavor is sweet, enter the heart, lung channel, there is heat-clearing, detoxify to select caulis lonicerae, dredging collateral
Function controls warm disease heating, toxic-heat and blood stasis, catarrhal jaundice, carbuncle sore tumefacting virus, arthralgia and myalgia.It is because of its nature and flavor to select blood clam
It is sweet, it is salty, it puts down, enters liver, the spleen channel, there is resolving sputum, softening hard masses to dissipate the stasis of blood, the function of disperse accumulation controls phlegm product, stomachache, noisy, acid regurgitation , Disorder lumps in the abdomen, scrofula
Scrofula, noma.Choosing pivot storage is to tremble with fear because its is bitter in taste, enter bladder warp, there is a diuresis, heat-clearing, the function of desinsection, controls heat gonorrhea, infirmity
It closes, jaundice, the erosion of vulva, leukorrhea, roundworm, infantile malnutrition due to digestive disturbances or intestinalparasites, hemorrhoid are swollen, wet sore.Select Fructus Forsythiae be because its is bitter in taste, it is cool, enter the heart, liver, gallbladder channel,
There is heat-clearing, detoxify, dissipating bind, the function of detumescence controls warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.Select tendril-leaved fritillary bulb
Mother be because of its nature and flavor bitter sweet, it is cool, enter lung channel, there is moistening lung dissipating bind, the function for resolving sputum of only coughing controls cough due to consumptive disease, spitting of blood of spitting, the heart
Chest pent-up, consumptive lung disease, lung carbuncle, goiter and tumor, scrofula, larynx numbness, acute mastitis.It is because of its nature and flavor toil to select green peel, and tepor enters liver, gallbladder channel,
There are soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm to control chest side of body gastral cavity pain, hernia, dyspepsia, breast is swollen, newborn core, chronic malaria addiction block.Selection is scolded
Son is because its is bitter in taste sour and astringent, and temperature enters lung, stomach, large intestine channel, astringes the lung, puckery intestines, the function of lower gas controls chronic cough aphonia, long
It rushes down, protracted dysentery, rectal prolapse is had blood in stool, uterine bleeding, under band, seminal emission, frequent micturition.Select rhizome of cyrtomium be because its is bitter in taste, it is cool, enter liver, stomach, have
Ascarid, silk ribbon, pinworm are killed, heat-clearing is detoxified, cool blood, the function of hemostasis, controls anemopyretic cold, and damp and hot ecchymosis is spitted blood, and bleeding from five sense organs or subcutaneous tissue, intestines wind is just
Blood, bloody flux, metrorrhagia, under.It is because its nature and flavor is sour to select dogwood fruit, and tepor has filling liver kidney, the function of puckery vital essence to control impotence,
Seminal emission, liver cold of insufficiency type heat, the heart shake arteries and veins and dissipate.It is to tremble with fear because its nature and flavor is sweet, enter lung, liver and kidney channel, there is heat-clearing to select the root bark of Chinese wolf-berry, cool blood
Function controls consumptive disease hectic fever night sweat, and lung heat cough and asthma is spitted blood, and bleeding from five sense organs or subcutaneous tissue, blood strangury is quenched one's thirst, hypertension, carbuncle swells, malignant sore.Selecting tortoise version is
Because the salty sweet and neutral of its nature and flavor, enters liver and kidney channel, there is an enriching yin, checking exuberance of yang, kidney tonifying, the function of strong bone controls the deficiency of the kidney yin, hectic fever due to yin labor heat,
It spits blood, bleeding from five sense organs or subcutaneous tissue, chronic cough, seminal emission, uterine bleeding, under, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
It is to have a nourshing kidney because of its nature and flavor sweet and neutral to select the fruit of Chinese wolfberry, moistening lung, tonifying liver, the function of improving eyesight, controls liver-kidney Yin deficiency, soreness and weakness of waist and knees,
It has a dizzy spell, the more tears of blurred vision, cough due to consumptive disease is quenched one's thirst, seminal emission.
Specific implementation mode
The drug dose of instant component is also to be obtained by plenty of explorations of the inventor, and the dosage of each component is following heavy
All tools have a better effect in amount range：
15-20 grams of Patrinia scaniosaefolia, 10-20 grams of cassia twig, 10-20 grams of trigone, 10-20 grams of oldenlandia diffusa, 3-9 grams of wartwort, Radix Astragali 5-15
Gram, 10-15 grams of scorpio, 5-15 grams of the stem of noble dendrobium, 5-15 grams of curcuma zedoary, 10-15 grams of the root bark of white mulberry, 10-15 grams of setose thistle, 10-20 grams of Cortex Phellodendri, mountain
5-15 grams of beans root, 5-15 grams of Snakegourd Fruit, 10-15 grams of madder, 5-15 grams of jujube, 5-10 grams of ginseng, 5-15 grams of Radix Angelicae Sinensis, Chinese blister beetle 5-15
Gram, 10-15 grams of rhizoma alismatis, 10-20 grams of plantain seed, 10-20 grams of dianthus superbus, 10-15 grams of caulis lonicerae, blood clam 10-20 Ke, pivots store 10-
15 grams, 5-15 grams of Fructus Forsythiae, 5-15 grams of bulbus fritillariae cirrhosae, 7-12 grams of green peel, 5-10 grams of myrobalan, 10-15 grams of rhizome of cyrtomium, 5-15 grams of dogwood fruit,
10-20 grams of the root bark of Chinese wolf-berry, tortoise version 5-15 grams, 10-15 grams of the fruit of Chinese wolfberry.
Preferably：
18 grams of Patrinia scaniosaefolia, 15 grams of cassia twig, 15 grams of trigone, 15 grams of oldenlandia diffusa, 6 grams of wartwort, 10 grams of Radix Astragali, 12 grams of scorpio, the stem of noble dendrobium
10 grams, 10 grams of curcuma zedoary, 12 grams of the root bark of white mulberry, 12 grams of setose thistle, 15 grams of Cortex Phellodendri, 10 grams of subprostrate sophora, 10 grams of Snakegourd Fruit, 12 grams of madder, jujube
10 grams, 8 grams of ginseng, 10 grams of Radix Angelicae Sinensis, 10 grams of Chinese blister beetle, 12 grams of rhizoma alismatis, 15 grams of plantain seed, 15 grams of dianthus superbus, 12 grams of caulis lonicerae, blood clam
12 grams of 15 Ke, pivots storage, 10 grams of Fructus Forsythiae, 10 grams of bulbus fritillariae cirrhosae, 9 grams of green peel, 8 grams of myrobalan, 12 grams of rhizome of cyrtomium, 10 grams of dogwood fruit, the root bark of Chinese wolf-berry
15 grams, tortoise version 10 grams, 12 grams of the fruit of Chinese wolfberry.
The preparation method of drug of the present invention is as follows
One, it stocks up
1, Patrinia scaniosaefolia：Crude drug is taken, impurity is removed and is slightly dried in the air with water spray, segment is dry；
2, cassia twig：It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit；
3, trigone：Net impurity is picked, is soaked in water, pulls out and moisturizes, is sliced, dries；
4, oldenlandia diffusa：Crude drug is taken, impurity is removed, wash quickly is net, slightly dries in the air, segment, dry, weeds out grey bits；
5, wartwort：Crude drug is taken, undesirable root is removed, impurity is cleaned, slightly moistened, segment, dry；
6, Radix Astragali：Net impurity is picked, remaining head and hollow the greater is removed, is soaked in water, pulls out, is sliced in time after moisturizing,
It dries；
7, scorpio：Clear water floats the matter that desalts, and dries or low baking temperature roasting is used；
8, the stem of noble dendrobium：The dry stem of noble dendrobium is taken, with bubble about saturating, the bored profit to eighty per cant, undesirable root and black branch, segment is removed, hits film, shine
It is dry；
9, curcuma zedoary：Crude drug is taken, impurity is removed, size stepping is cleaned, slightly impregnated, and is taken out, is moisturized, shave, dry, is weeded out
Clast；
10, the root bark of white mulberry：Grey bits are brushed away, is cleaned, is moisturized rear chopping, dry；
11, setose thistle：Impurity is picked, clear water is cleaned, moisturized, segment is dried；
12, Cortex Phellodendri：Impurity is picked, is eluted with water, is pulled out, is moisturized, slice or chopping are dried；
13, subprostrate sophora：Net impurity is picked, thickness stepping is soaked in water, pulls out, is sliced, dries after moisturizing；
14, Snakegourd Fruit：Crude drug is taken, impurity and carpopodium are removed, is cleaned, is flattened, chopping or fritter are dry；
15, madder：Impurity is removed, is cleaned, is moisturized, cut sheet or section, it is dry, weed out clast；
16, jujube：Net impurity is picked, is dried；
17, ginseng：Except removing LU, segment；
18, Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit, when slightly drying in the air to uniform humidity inside and outside, slice dries；
19, Chinese blister beetle：Net impurity is picked, foot, wing are removed；
20, rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, bored profit to uniform humidity inside and outside,
Slice, is dried；
21, plantain seed：Impurity is picked, spare, empty grain are weeded out；
22, dianthus superbus：Net impurity is picked, undesirable root is removed, is cleaned, bored profit, segment is dried；
23, caulis lonicerae：Impurity is picked, is soaked in water, is moisturized, is sliced, dries；
24, blood clam：It cleans and dries, pulverize；
25, pivot stores：Impurity and root are removed, cleans, softens, segment is dried；
26, Fructus Forsythiae：Net impurity is picked, is rubbed open, discarding stalk is removed；
27, bulbus fritillariae cirrhosae：Impurity is picked, is slightly steeped, is pulled out with water, bored profit is peelled off the heart, dried；
28, green peel：Net impurity is picked, is soaked in water, is pulled out, is moisturized, is sliced, dries；
29, myrobalan：Crude drug is taken, impurity, cleaning, drying are removed；
30, rhizome of cyrtomium：It is slightly soaked, is taken out with clear water, each watering is primary sooner or later, softens, and is sliced, dries；
31, dogwood fruit：It cleans, removes removal core and impurity, dry；
32, the root bark of Chinese wolf-berry：Impurity and core are picked, is slightly washed, segment is dried；
33, tortoise version：It is impregnated with clear water, scrapes off residual meat, cleaned, dry, knock fritter；
34, the fruit of Chinese wolfberry：It winnows with a dustpan net impurity, plucks remaining stalk and the base of a fruit.
Two, it prepares
1, by the Patrinia scaniosaefolia of the weight, cassia twig, trigone, oldenlandia diffusa, wartwort, Radix Astragali, scorpio, the stem of noble dendrobium, curcuma zedoary, the root bark of white mulberry,
Setose thistle, Cortex Phellodendri, subprostrate sophora, Snakegourd Fruit, madder, jujube, ginseng, Radix Angelicae Sinensis, Chinese blister beetle, rhizoma alismatis, plantain seed, dianthus superbus, caulis lonicerae, corrugation
Sub-, pivots storage, Fructus Forsythiae, bulbus fritillariae cirrhosae, green peel, myrobalan, rhizome of cyrtomium, dogwood fruit, the root bark of Chinese wolf-berry, tortoise version, the fruit of Chinese wolfberry are put into decocting container, are added
8 times of water amount, after impregnating 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, by the
One time decoction liquor is poured into container；
2, the dregs of a decoction of filtering are added into 6 times of amounts of water, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
3, it decoction liquor will be mixed evenly twice, and be divided into 3 doses and take.
Patrinia scaniosaefolia is clearing heat and detoxicating in prescription, apocenosis broken stasis of blood, and it is monarch drug in a prescription that cassia twig, which has sweating expelling pathogenic factors from muscles and skin, both functions of warming meridians and promoting circulation of qi,；
Trigone blood-breaking, promoting the circulation of qi, disperse accumulation, analgesic, oldenlandia diffusa have heat-clearing, dampness removing, the function of removing toxic substances, with wartwort, Radix Astragali, scorpio, stone
Dry measure used in former times, curcuma zedoary, the root bark of white mulberry, setose thistle be ministerial drug, ten simply medicine play clearing heat and detoxicating, apocenosis broken stasis of blood, blood-breaking, dampness removing, hair jointly
The effect of sweat expelling pathogenic factors from muscles and skin, warming meridians and promoting circulation of qi, treatment cervical carcinoma effect is comprehensive, and based on clearing heat and cooling blood, hemostasis, dissolving stasis, can effect a permanent cure；It is yellow
Cypress has nourishing yin and lessening fire, function and subprostrate sophora, Snakegourd Fruit, madder, jujube, ginseng, Radix Angelicae Sinensis, Chinese blister beetle, rhizoma alismatis, the Chinese herbaceous peony of moisturize laxation
Son, dianthus superbus, caulis lonicerae, blood clam, pivots storage, Fructus Forsythiae, bulbus fritillariae cirrhosae are adjutant；Green peel has a soothing the liver relieving stagnant Qi, the function of dissipating bind dissolving phlegm with
Remaining all medicines are to make medicine, are to take stopgap measures.
Drug of the present invention has clearing heat and detoxicating, apocenosis broken stasis of blood, blood-breaking, nourishing yin and lessening fire, soothing the liver relieving stagnant Qi, dissipating bind dissolving phlegm
Function, for treating cervical carcinoma, short treating period, quick, non-relapse after healing.
Carry out the advantageous effect of the present invention is further explained the drug below by way of test example, these test examples include this hair
The animal toxicity test report of bright drug and clinical observation on the therapeutic effect data.
The animal toxicity test of [test example 1] drug of the present invention is reported：
Rabbit 30, male and female dual-purpose, 2.0-2.5kg of weight is taken to be divided to two groups, every group 15, one of which is tested for overdose
Group, another group is normal amount test group.Super quantity group is 20ml/kg, normal amount 10ml/kg, and administering mode gives for administration by gavage
Medicine even served 7 days twice daily, the reaction of observation administration daily, the results showed that two groups of rabbit activities, diet are normal, and drug is without bad
Toxic side effect.
The clinical observation on the therapeutic effect of [test example 2] drug of the present invention
1, general information
Accept cervical carcinoma out-patient totally 56 for medical treatment.
2, diagnostic criteria
Classical symptom is：Irregularly cloudy bleeding, vaginal discharge increase vagina, and taste is stench, the symptom of whole body have fever,
Become thin, anaemia, oedema, tired fatigue and asthenia etc..
3, therapy
Above-mentioned medicament is selected, is taken to patient, each taking 1 dose, early daily, evening respectively takes 1 time, 30 days as a treatment course, continuously
It takes 1 course for the treatment of.
4, efficacy assessment standard
It is effective：Cervical carcinoma symptom disappears, and restores normal, and follow-up 2 years is without recurrence；
It improves：Irregularly cloudy bleeding, vaginal discharge increase patient's vagina, and taste smells as of rotten fish, generates heat, becoming thin, anaemia, water
The phenomenon that swollen, tired fatigue and asthenia, mitigates, and the symptoms were significantly improved for cervical carcinoma, gradually restores normal；
In vain：Improvement standard person is not achieved.
5, treatment results（It see the table below）
In above-mentioned treatment, with drug therapy cervical cancer patient 56 of the present invention, as a result effective 46, obvious effective rate 82.14%,
It improves 7, improvement rate 12.5%, invalid 3, total effective rate 94.64%.
Claims (3)
1. a kind of drug for treating cervical carcinoma, it is characterised in that：It is made of the bulk pharmaceutical chemicals in following weight range：
15-20 grams of Patrinia scaniosaefolia, 10-20 grams of cassia twig, 10-20 grams of trigone, 10-20 grams of oldenlandia diffusa, 3-9 grams of wartwort, Radix Astragali 5-15
Gram, 10-15 grams of scorpio, 5-15 grams of the stem of noble dendrobium, 5-15 grams of curcuma zedoary, 10-15 grams of the root bark of white mulberry, 10-15 grams of setose thistle, 10-20 grams of Cortex Phellodendri, mountain
5-15 grams of beans root, 5-15 grams of Snakegourd Fruit, 10-15 grams of madder, 5-15 grams of jujube, 5-10 grams of ginseng, 5-15 grams of Radix Angelicae Sinensis, Chinese blister beetle 5-15
Gram, 10-15 grams of rhizoma alismatis, 10-20 grams of plantain seed, 10-20 grams of dianthus superbus, 10-15 grams of caulis lonicerae, blood clam 10-20 Ke, pivots store 10-
15 grams, 5-15 grams of Fructus Forsythiae, 5-15 grams of bulbus fritillariae cirrhosae, 7-12 grams of green peel, 5-10 grams of myrobalan, 10-15 grams of rhizome of cyrtomium, 5-15 grams of dogwood fruit,
10-20 grams of the root bark of Chinese wolf-berry, tortoise version 5-15 grams, 10-15 grams of the fruit of Chinese wolfberry.
2. drug according to claim 1, wherein the dosage of each bulk pharmaceutical chemicals is：
18 grams of Patrinia scaniosaefolia, 15 grams of cassia twig, 15 grams of trigone, 15 grams of oldenlandia diffusa, 6 grams of wartwort, 10 grams of Radix Astragali, 12 grams of scorpio, the stem of noble dendrobium
10 grams, 10 grams of curcuma zedoary, 12 grams of the root bark of white mulberry, 12 grams of setose thistle, 15 grams of Cortex Phellodendri, 10 grams of subprostrate sophora, 10 grams of Snakegourd Fruit, 12 grams of madder, jujube
10 grams, 8 grams of ginseng, 10 grams of Radix Angelicae Sinensis, 10 grams of Chinese blister beetle, 12 grams of rhizoma alismatis, 15 grams of plantain seed, 15 grams of dianthus superbus, 12 grams of caulis lonicerae, blood clam
12 grams of 15 Ke, pivots storage, 10 grams of Fructus Forsythiae, 10 grams of bulbus fritillariae cirrhosae, 9 grams of green peel, 8 grams of myrobalan, 12 grams of rhizome of cyrtomium, 10 grams of dogwood fruit, the root bark of Chinese wolf-berry
15 grams, tortoise version 10 grams, 12 grams of the fruit of Chinese wolfberry.
3. the preparation method of drug according to claim 1 or claim 2, it includes the following steps：
（One）Stock
（1）Patrinia scaniosaefolia：Crude drug is taken, impurity is removed and is slightly dried in the air with water spray, segment is dry；
（2）Cassia twig：It is slightly impregnated, is pulled out with water, to saturating, slice dries, weeds out bits bored profit；
（3）Trigone：Net impurity is picked, is soaked in water, pulls out and moisturizes, is sliced, dries；
（4）Oldenlandia diffusa：Crude drug is taken, impurity is removed, wash quickly is net, slightly dries in the air, segment, dry, weeds out grey bits；
（5）Wartwort：Crude drug is taken, undesirable root is removed, impurity is cleaned, slightly moistened, segment, dry；
（6）Radix Astragali：Net impurity is picked, remaining head and hollow the greater is removed, is soaked in water, pulls out, is sliced in time after moisturizing,
It dries；
（7）Scorpio：Clear water floats the matter that desalts, and dries or low baking temperature roasting is used；
（8）The stem of noble dendrobium：The dry stem of noble dendrobium is taken, with bubble about saturating, the bored profit to eighty per cant, undesirable root is removed and film is hit in black branch, segment,
It dries；
（9）Curcuma zedoary：Crude drug is taken, impurity is removed, size stepping is cleaned, slightly impregnated, and is taken out, is moisturized, shave, dry, is weeded out
Clast；
（10）The root bark of white mulberry：Grey bits are brushed away, is cleaned, is moisturized rear chopping, dry；
（11）Setose thistle：Impurity is picked, clear water is cleaned, moisturized, segment is dried；
（12）Cortex Phellodendri：Impurity is picked, is eluted with water, is pulled out, is moisturized, slice or chopping are dried；
（13）Subprostrate sophora：Net impurity is picked, thickness stepping is soaked in water, pulls out, is sliced, dries after moisturizing；
（14）Snakegourd Fruit：Crude drug is taken, impurity and carpopodium are removed, is cleaned, is flattened, chopping or fritter are dry；
（15）Madder：Impurity is removed, is cleaned, is moisturized, cut sheet or section, it is dry, weed out clast；
（16）Jujube：Net impurity is picked, is dried；
（17）Ginseng：Except removing LU, segment；
（18）Radix Angelicae Sinensis：Impurity is picked, is cleaned, bored profit, when slightly drying in the air to uniform humidity inside and outside, slice dries；
（19）Chinese blister beetle：Net impurity is picked, foot, wing are removed；
（20）Rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, bored profit to uniform humidity inside and outside,
Slice, is dried；
（21）Plantain seed：Impurity is picked, spare, empty grain are weeded out；
（22）Dianthus superbus：Net impurity is picked, undesirable root is removed, is cleaned, bored profit, segment is dried；
（23）Caulis lonicerae：Impurity is picked, is soaked in water, is moisturized, is sliced, dries；
（24）Blood clam：It cleans and dries, pulverize；
（25）Pivot stores：Impurity and root are removed, cleans, softens, segment is dried；
（26）Fructus Forsythiae：Net impurity is picked, is rubbed open, discarding stalk is removed；
（27）Bulbus fritillariae cirrhosae：Impurity is picked, is slightly steeped, is pulled out with water, bored profit is peelled off the heart, dried；
（28）Green peel：Net impurity is picked, is soaked in water, is pulled out, is moisturized, is sliced, dries；
（29）Myrobalan：Crude drug is taken, impurity, cleaning, drying are removed；
（30）Rhizome of cyrtomium：It is slightly soaked, is taken out with clear water, each watering is primary sooner or later, softens, and is sliced, dries；
（31）Dogwood fruit：It cleans, removes removal core and impurity, dry；
（32）The root bark of Chinese wolf-berry：Impurity and core are picked, is slightly washed, segment is dried；
（33）Tortoise version：It is impregnated with clear water, scrapes off residual meat, cleaned, dry, knock fritter；
（34）The fruit of Chinese wolfberry：It winnows with a dustpan net impurity, plucks remaining stalk and the base of a fruit；
（Two）It prepares
（1）By the Patrinia scaniosaefolia of the weight, cassia twig, trigone, oldenlandia diffusa, wartwort, Radix Astragali, scorpio, the stem of noble dendrobium, curcuma zedoary, the root bark of white mulberry,
Setose thistle, Cortex Phellodendri, subprostrate sophora, Snakegourd Fruit, madder, jujube, ginseng, Radix Angelicae Sinensis, Chinese blister beetle, rhizoma alismatis, plantain seed, dianthus superbus, caulis lonicerae, corrugation
Sub-, pivots storage, Fructus Forsythiae, bulbus fritillariae cirrhosae, green peel, myrobalan, rhizome of cyrtomium, dogwood fruit, the root bark of Chinese wolf-berry, tortoise version, the fruit of Chinese wolfberry are put into decocting container, are added
8 times of water amount, after impregnating 100 minutes, high heat decoction boiling, then with being cooked by slow fire 20 minutes, filter to obtain first time decoction liquor, by the
One time decoction liquor is poured into container；
（2）The dregs of a decoction of filtering are added into 6 times of amounts of water, are boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second of decoction liquor；
（3）It decoction liquor will be mixed evenly twice, and be divided into 3 doses and take.
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