CN104056225A

CN104056225A - Medicine for treating atrial fibrillation and preparation method thereof

Info

Publication number: CN104056225A
Application number: CN201410285307.0A
Authority: CN
Inventors: 卢文华
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-06-24
Filing date: 2014-06-24
Publication date: 2014-09-24

Abstract

The invention discloses a medicine for treating atrial fibrillation and a preparation method thereof. The medicine for treating atrial fibrillation is prepared by dens draconis, rhizoma nardostachyos, large jujube, lophatherum stem and leaves, pearl, arborvitae seed, pyrola, ginger, rosewood heart wood, Chinese magnoliavine and epimeddium according to certain weight ratio. The medicine has the functions of tranquilizing by nourishing the heart, clearing heat and removing worries, and benefiting spleen and stomach; and can be used for treating atrial fibrillation with fast effectiveness, good curative effect and no recurrence.

Description

A kind of medicine for the treatment of atrial fibrillation and preparation method thereof

Technical field

The present invention relates to a kind of medicine that is used for the treatment of atrial fibrillation and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Atrial fibrillation is one of modal arrhythmia, is the atrial rhythm that atrium is unordered excitement and ineffective contraction, is to cause by atrium-leading reentrant cycle the room rule disorder that many micro reentry rings cause, very common in old people.Be found in all organic heart disease patients, non-organic cardiac, also atrial fibrillation can occur, the high persistent period of sickness rate is long, also can cause serious complication, as heart failure and arterial thrombosis.Cause patient's deformity or case fatality rate to increase.At present, western medicine atrial fibrillation poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of effective treatment atrial fibrillation in people.

Summary of the invention

The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment atrial fibrillation, thereby has completed the present invention.

Object of the present invention is just to provide a kind of composition of medicine that can effectively treat atrial fibrillation.

Another object of the present invention has just been to provide the preparation method of this composition of medicine.

Medicine of the present invention selects Dens Draconis, Radix Et Rhizoma Nardostachyos, Fructus Jujubae, Folium Bambusae, Margarita, Semen Platycladi, Herba Pyrolae, Rhizoma Zingiberis Recens, Lignum Dalbergiae Odoriferae, Fructus Schisandrae Chinensis, Herba Epimedii, Colla Corii Asini, Bulbus Lilii, succinum, Semen sojae atricolor, Radix Achyranthis Bidentatae, Exocarpium Citri Rubrum, Caulis Bambusae In Taenia, Lumbricus, Radix Pseudostellariae, Herba Ecliptae, Massa Medicata Fermentata, Oletum Trogopterori, Cortex Cinnamomi, Pericarpium Citri Reticulatae, Lignum Santali Albi, Bulbus Allii Macrostemonis, Fructus Tribuli, Poria, Radix Platycodonis, Radix Asparagi, Hirudo, Flos Chrysanthemi medicine to combine, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can fast treating atrial fibrillation.Wherein select Dens Draconis to be because its nature and flavor are puckery, cool, enter the heart, Liver Channel, have tranquillizing the mind by relieving convulsion, the function of heat clearing away and restlessness relieving, Zhi Jing Epilepsy is demented, and dysphoria with smothery sensation is uneasy, insomnia and dreamful sleep.Select Radix Et Rhizoma Nardostachyos to be because its nature and flavor are sweet, temperature, enters spleen, stomach warp, has regulating QI to relieve pain, and activating spleen and strengthening stomach, treats for stomachache, distension and fullness of the chest and abdomen, headache, hysteria, beriberi.Select Fructus Jujubae to be because its nature and flavor are sweet, temperature, enters spleen, stomach warp, has spleen reinforcing stomach function regulating, and supplementing QI for promoting the production of body fluid adjusts battalion to defend, and separates the function of poison of drug, controls insufficiency of stomach lack of appetite, the weak loose stool of spleen, and qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Selecting Folium Bambusae is because its property slightly sweet flavor, cold, enters the heart, lung, gallbladder, stomach warp, has clearing heat and relieving fidgetness, and the function of the diuresis of promoting the production of body fluid controls that calentura is tired drinks, and little youngster shies Epilepsy, and cough with dyspnea is told nosebleed, flushed complexion, oliguria with reddish urine, erosion of the oral mucosa tongue boil.Select Margarita to be because its property sweet-salty is cold, enter the heart, Liver Channel, have tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, and removing nebula improving eyesight, the function of removing toxic substances and promoting granulation, controls palpitation with fear, palpitation with a distress feeling, epilepsy, infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, sore throat aphtha, the raw cataracta of order, skin infection does not close up for a long time.Select Semen Platycladi to be because its nature and flavor are sweet, flat, enter the heart, liver, spleen channel, there is tranquilizing by nourishing the heart, the function of loosening bowel to relieve constipation, controls palpitation with fear, insomnia, seminal emission, night sweat, the function of constipation.Selecting Herba Pyrolae is that temperature, enters liver, kidney two warps, has tonify deficiency because of its nature and flavor sweetness and bitterness, kidney tonifying, and expelling wind and removing dampness, the function of promoting blood flow to regulate menstruation, controls weak cough, over-strained hemoptysis, rheumatic arthritis, metrorrhagia, leucorrhea, traumatic hemorrhage.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enters lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting, opens the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Lignum Dalbergiae Odoriferae to be because its nature and flavor are pungent, temperature, enters liver, spleen channel, regulate the flow of vital energy, and hemostasis, clots absorbing, the function of analgesic therapy, controls haematemesis, spitting of blood, incised wound is hemorrhage, traumatic injury, carbuncle skin ulcer is swollen, lumbago, skelalgia of rheumatism, heart peratodynia.Select Fructus Schisandrae Chinensis to be because its nature and flavor are sour, temperature, enters lung, kidney channel, astringes the lung, and nourishing kidney, promotes the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Selecting Herba Epimedii is that temperature, enters liver, kidney channel, has kidney invigorating and YANG supporting because of its property acrid-sweet flavor, and the function of expelling wind and removing dampness is controlled sexual impotence erectile problem, dribbling urination, and muscles and bones contraction is anxious, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, four feet are meciless.Select Colla Corii Asini to be because its nature and flavor are sweet flat, enter lung, liver, kidney channel, have nourishing YIN and supplementing blood, antiabortive function, controls blood deficiency, and cough due to consumptive disease, is had blood in stool at haematemesis, epistaxis, menoxenia, and metrorrhagia, controls leakage.Select Bulbus Lilii to be because its property sweet and slightly bitter taste is flat, enter the heart, lung meridian, have nourishing the lung to arrest cough, the function of clearing away heart-fire for tranquillization, controls pulmonary tuberculosis chronic cough, cough and spit expectorant blood, and after calentura, waste heat is unclear, fidgets due to deficiency palpitation with fear, staring spells, beriberi edema.Select succinum to be because its nature and flavor are sweet, flat, enter the heart, liver, small intestine meridian, there is tranquillizing the mind by relieving convulsion, dissipating blood stasis hemostasis, the function of relieving stranguria by diuresis, controls infantile convulsion epilepsy, palpitation with fear insomnia, stranguria with blood hematuria, urinary obstruction, women's amenorrhea, stops the stasis of blood stomachache puerperal, skin sore, traumatic injuries.Select Semen sojae atricolor to be because its nature and flavor are sweet, flat, enter spleen, kidney channel, invigorate blood circulation, diuretic, dispels the wind, the function of removing toxic substances, the swelling of harnessing the river is full, pathogenic wind-toxic beriberi, jaundice clonic spasm of the muscle, puerperal puerperal tetanus, locked mouth, carbuncle sore tumefacting virus; Separate poison of drug.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and the function of subduing inflammation, controls gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe in invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select Exocarpium Citri Rubrum to be because its nature and flavor are arduous, temperature, enters brothers' sun, the sun, Yangming Channel, has expectorant, promoting the circulation of QI, and alleviating distention in middle-JIAO, the function of eliminating stagnation, controls wind and cold phlegmatic cough, feels sick, guttation, chest pain feeling of distension and oppression.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduces phlegm, and the function of emesis is controlled dysphoria with smothery sensation vomiting, singultus, and expectorant heat syndrome cough is breathed heavily, spit blood, and epistaxis, metrorrhagia, malignant histocytosis, fetal movement ， Jing Epilepsy.Select Lumbricus to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, there is heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control height fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Selecting Radix Pseudostellariae is that tepor, enters the heart, spleen, lung three warps, has the function of tonifying the lung, spleen invigorating, controls cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Herba Ecliptae to be because its nature and flavor picric acid is cool, enter liver, kidney channel, have removing heat from blood, hemostasis, the kidney invigorating, the function of tonifying YIN, controls haematemesis, hemoptysis, epistaxis, hematuria, has blood in stool, dysentery, knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, dysentery, pudendum pruritus due to damp pathogen.Select Massa Medicata Fermentata to be because its nature and flavor sweet, acrid, warm enters upright stone tablet, stomach warp, have invigorating the spleen and regulating the stomach, the function helping digestion in adjusting, controls retention of food and drink, feeling of stuffiness in chest abdominal distention, and vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen is hard long-pending.Selecting Oletum Trogopterori is that temperature, enters liver, spleen channel because of its property bitter but sweet flavor, and the raw function with there being promoting the circulation of blood pain relieving, controls all pains of trusted subordinate's vim and vigour, women's amenorrhea, and postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite, fry with hemostasis, controls metrorrhagia, menorrhagia, and leucorrhea with bloody discharge is without cease.Selecting Cortex Cinnamomi is that heat, enters kidney, spleen, urinary bladder channel because of its property acrid-sweet flavor, has complement sun, warming the spleen and stomach, removing accumulated cold, the function of promoting blood circulation, controls decline of the fire from the gate of life, cold extremities faint pulse, and YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Select Pericarpium Citri Reticulatae to be because its nature and flavor are bitter, pungent, temperature, returns lung, spleen channel, has regulating qi-flowing for strengthening spleen, and the function of drying dampness to eliminate phlegm, controls fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select Lignum Santali Albi to be because its nature and flavor are pungent, temperature, enters spleen, stomach, lung meridian, regulates the flow of vital energy, and the function of stomach function regulating, controls trusted subordinate's pain, dysphagic vomiting, and chest and diaphragm does not relax.Select Bulbus Allii Macrostemonis to be because its nature and flavor are arduous, temperature, enters meridian of Hand-YANG MING, regulates the flow of vital energy, and the chest stuffiness relieving, activates yang, and the function of eliminating stagnation is controlled the thorough back of the body of obstruction of qi in the chest and cardialgia, and gastral cavity painful abdominal mass is not relaxed, and retches, heavy after dysentery, furuncle.Selecting Fructus Tribuli is because its nature and flavor toil, and temperature, enters liver, lung meridian, has loose wind, improving eyesight, and the therapeutic method to keep the adverse QI flowing downwards, the function of promoting the circulation of blood, controls headache, itching over the body, the conjunctival congestion nebula that swell, fullness in the chest, cough with dyspnea ， mass in the abdomen, breast difficulty, carbuncle, scrofula.Select Poria to be because its property slightly sweet flavor is flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, controls dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Select Radix Platycodonis to be because its nature and flavor toil is flat, enter lung, stomach warp, have out lung qi dispersing gas, the function of the evacuation of pus of eliminating the phlegm, controls exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Select Radix Asparagi to be because its nature and flavor sweetness and bitterness is cold, enter lung, kidney channel, have YIN nourishing, moisturize, lung heat clearing, the function of pathogenic fire reducing, controls fever due to yin deficiency, and cough is spitted blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain, quenches one's thirst, constipation.Select Hirudo to be because the salty hardship of its nature and flavor is flat, poisonous, enter liver, urinary bladder channel, have removing blood stasis, removing blood stasis, the function of stimulating the menstrual flow, controls blood-retention ， mass in the abdomen, gathers, women's amenorrhea, blood stasis becomes consumptive disease, injury from falling down, conjunctival congestion with ophthalmalgia, nebula.Select Flos Chrysanthemi to be because its nature and flavor sweetness and bitterness is cool, enter lung, Liver Channel, has dispelling wind, the heat that disappears, and improving eyesight, the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.

The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Dens Draconis 3-9 gram of Radix Et Rhizoma Nardostachyos 10-20 gram of Fructus Jujubae 10-14 gram

Folium Bambusae 5-10 gram of Margarita 2-3 gram of Semen Platycladi 10-14 gram

Herba Pyrolae 5-10 gram of Rhizoma Zingiberis Recens 5-15 gram of Lignum Dalbergiae Odoriferae 5-10 gram

Fructus Schisandrae Chinensis 3-10 gram of Herba Epimedii 10-14 gram of Colla Corii Asini 5-15 gram

Bulbus Lilii 15-25 gram of succinum 1-3 gram of Semen sojae atricolor 15-25 gram

Radix Achyranthis Bidentatae 5-10 gram of Exocarpium Citri Rubrum 3-10 gram of Caulis Bambusae In Taenia 5-10 gram

Lumbricus 10-14 gram of Radix Pseudostellariae 5-15 gram of Herba Ecliptae 10-20 gram

Massa Medicata Fermentata 5-15 gram of Oletum Trogopterori 5-15 gram of Cortex Cinnamomi 5-10 gram

Pericarpium Citri Reticulatae 5-15 gram of Lignum Santali Albi 10-14 gram of Bulbus Allii Macrostemonis 5-15 gram

Fructus Tribuli 5-10 gram of Poria 10-14 gram of Radix Platycodonis 10-20 gram

Radix Asparagi 5-15 gram of Hirudo 1-3 gram of Flos Chrysanthemi 5-15 gram.

Preferable amount is

12 grams, 15 grams of Fructus Jujubaes of 6 grams of Radix Et Rhizoma Nardostachyos of Dens Draconis

12 grams of 3 grams of Semen Platycladi of 8 grams of Margaritas of Folium Bambusae

8 grams of 10 grams of Lignum Dalbergiae Odoriferae of 8 grams of Rhizoma Zingiberis Recenss of Herba Pyrolae

15 grams, 12 grams of Colla Corii Asini of 5 grams of Herba Epimedii of Fructus Schisandrae Chinensis

20 grams of 2 grams of Semen sojae atricolor of 20 grams of succinums of Bulbus Lilii

8 grams of 5 grams of Caulis Bambusae In Taenia of 8 grams of Exocarpium Citri Rubrums of Radix Achyranthis Bidentatae

15 grams of 10 grams of Herba Ecliptaes of 12 grams of Radix Pseudostellariaes of Lumbricus

8 grams of 10 grams of Cortex Cinnamomis of 10 grams of Oletum Trogopteroris of Massa Medicata Fermentata

10 grams of 12 grams of Bulbus Allii Macrostemonis of 10 grams of Lignum Santali Albis of Pericarpium Citri Reticulatae

15 grams of 12 grams of Radix Platycodoniss of 8 grams of Poria of Fructus Tribuli

10 grams of 2 grams of Flos Chrysanthemis of 10 grams of Hirudos of Radix Asparagi.

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Dens Draconis: outwash earth, smash;

2, Radix Et Rhizoma Nardostachyos: Ex-all impurity, rob water speed and wash, to pull out, cutting, dries;

3, Fructus Jujubae: choose clean impurity, dry;

4, Fructus Jujubae: choose clean impurity, dry;

5, Margarita powder: get Margarita and clean, with cloth, wrap, with bean curd and water, boil altogether approximately 2 hours, take out, clean, smash to pieces, add water a little, be ground into superfine powder, be dried;

6, Semen Platycladi: choose clean impurity, remove residual shell and plant skin;

7, Herba Pyrolae: choose decontamination, sieve removes silt, cleans, and slightly profit, chops up, and dries;

8, Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;

9, Lignum Dalbergiae Odoriferae: after water logging, steam to appropriateness, pound sheet or flaking, dry;

10, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

11, Herba Epimedii: choose clean impurity, destemming, shredding, sieve removes chip;

12, Colla Corii Asini: smash use to pieces;

13, Bulbus Lilii: choose decontamination, black lobe, the ash disposal of winnowing with a dustpan bits;

14, succinum: choose clean impurity, the used time smashs to pieces and is ground into fine powder;

15, Semen sojae atricolor: choose clean impurity, dry;

16, Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;

17, Exocarpium Citri Rubrum: choose decontamination, outwash, used time folding is broken;

18, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off ash bits, be kneaded into little group or cutting;

19, Lumbricus: choose decontamination, water rinses, and pulls out in time, dries cutting;

20, Radix Pseudostellariae: extract fibrous root, dry;

21, Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;

22, Massa Medicata Fermentata: get wheat bran and sprinkle evenly in heat pot, the cigarette of having waited, pours Massa Medicata Fermentata into, fries to yellow, takes out, and sieve removes wheat bran, cools;

23, Oletum Trogopterori: choose clean impurity, smash or sieve dedust bits;

24, Cortex Cinnamomi: choose clean impurity, the used time smashes, or scrape off rough bark, by warm water, infiltrating a moment, section, dries;

25, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, clean, soften, shredding, dries or cold drying, sieve dedust bits;

26, Lignum Santali Albi: be soaked in water, pound sheet or split brokenly, dries;

27, Bulbus Allii Macrostemonis: choose decontamination, the sieve of winnowing with a dustpan goes whisker;

28, Fructus Tribuli: float silt, the hard thorn that Ex-all is residual;

29, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

30, Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

31, Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, dry;

32, Hirudo: clean, vexed soft, cutting, dries;

33, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity.

Two, preparation

1, by the Dens Draconis of described weight, Radix Et Rhizoma Nardostachyos, Fructus Jujubae, Folium Bambusae, Semen Platycladi, Herba Pyrolae, Rhizoma Zingiberis Recens, Lignum Dalbergiae Odoriferae, Fructus Schisandrae Chinensis, Herba Epimedii, Colla Corii Asini, Bulbus Lilii, Semen sojae atricolor, Radix Achyranthis Bidentatae, Exocarpium Citri Rubrum, Caulis Bambusae In Taenia, Lumbricus, Radix Pseudostellariae, Herba Ecliptae, Massa Medicata Fermentata, Oletum Trogopterori, Cortex Cinnamomi, Pericarpium Citri Reticulatae, Lignum Santali Albi, Bulbus Allii Macrostemonis, Fructus Tribuli, Poria, Radix Platycodonis, Radix Asparagi, Hirudo, Flos Chrysanthemi medicine, decoct with water, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 30 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.

2, will filter for the first time rear medicinal residues and add 6 times of amounts of water, and decoct boiling, then use slow fire boiling 40 minutes, filter to obtain decoction liquor for the second time.

3, twice decoction liquor mixed, then use slow fire boiling 10 minutes, pour in container, add the Margarita powder of described weight and Succinum powder to stir, obtain medicinal liquid, medicinal liquid is divided into 6 doses and takes.

Medicine of the present invention has tranquilizing by nourishing the heart, clearing heat and relieving fidgetness, and the function of strengthening the spleen stomach function regulating, is used for the treatment of atrial fibrillation, short treating period, instant effect, has no side effect.

The specific embodiment

By test example, further set forth below the beneficial effect of medicine of the present invention, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The observations of [test example 2] Drug therapy atrial fibrillation of the present invention

1, physical data

Accept Patients With Atrial Fibrillation totally 32 examples for medical treatment.

2, diagnostic criteria

Clinical manifestation:

(1) symptom

During atrial attack, except the hemodynamics change that basic heart disease causes, because atrial fibrillation makes the contractile function in atrium, lose, it is irregular that ventricular systole becomes, and chamber rate speeds, and the modal symptom of patient is cardiopalmus.As merge coronary heart disease, patient can occur angina pectoris, dizzy, faint, seriously can there is heart failure and shock.As the person that merges rheumatic heart disease of mitral stenosis, often bringing out acute lung edema, with pulmonary hypertension person, can spit blood.

Some is type and middling speed type atrial fibrillation at a slow speed, and patient can be without any symptom, especially common old people, while being everlasting health check-up or Electrocardioscopy, finds.

(2) sign

1. original cardiopathic sign, to send out difference cardiopathic different because of former for atrial fibrillation person sign.

2. three of atrial fibrillation large signs: not etc., the rhythm of the heart is definitely not uneven, pulse deficit for apex first heart sound power.

3. thromboembolism is levied: brain, lung and limb vessel thromboembolism can occur patients with atrial fibrillation levies, and the incidence rate of thromboembolism and age, atrium size are relevant with basic heart disease.Patients with atrial fibrillation cerebral infarction incidence rate is higher 5 times than normal population.

3, Therapeutic Method

Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day, early, middle and late respectively clothes 1 time, 15 days was a course for the treatment of, took continuously 3 courses for the treatment of.

4, efficacy assessment standard

Effective: atrial fibrillation transference cure, recovery from illness, observes half a year without bounce-back person;

Take a turn for the better: atrial fibrillation symptom is obviously improved, and body constitution progressively strengthens;

Invalid: atrial fibrillation symptom, without change, does not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, by Drug therapy Patients With Atrial Fibrillation 32 examples of the present invention, effective 28 examples of result, obvious effective rate is 87.50%, 2 examples that take a turn for the better, and improvement rate is 6.75%, invalid 2 examples, total effective rate is 93.75%.

Claims

1. a medicine for the treatment of atrial fibrillation, is characterized in that: it is to be made by the crude drug in following weight range:

Folium Bambusae 5-10 gram of Margarita 2-3 gram of Semen Platycladi 10-14 gram

Fructus Tribuli 5-10 gram of Poria 10-14 gram of Radix Platycodonis 10-20 gram

Radix Asparagi 5-15 gram of Hirudo 1-3 gram of Flos Chrysanthemi 5-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Dens Draconis: outwash earth, smash;

(2) Radix Et Rhizoma Nardostachyos: Ex-all impurity, rob water speed and wash, to pull out, cutting, dries;

(3) Fructus Jujubae: choose clean impurity, dry;

(4) Fructus Jujubae: choose clean impurity, dry;

(5) Margarita powder: get Margarita and clean, with cloth, wrap, with bean curd and water, boil altogether approximately 2 hours, take out, clean, smash to pieces, add water a little, be ground into superfine powder, be dried;

(6) Semen Platycladi: choose clean impurity, remove residual shell and plant skin;

(7) Herba Pyrolae: choose decontamination, sieve removes silt, cleans, and slightly profit, chops up, and dries;

(8) Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;

(9) Lignum Dalbergiae Odoriferae: after water logging, steam to appropriateness, pound sheet or flaking, dry;

(10) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

(11) Herba Epimedii: choose clean impurity, destemming, shredding, sieve removes chip;

(12) Colla Corii Asini: smash use to pieces;

(13) Bulbus Lilii: choose decontamination, black lobe, the ash disposal of winnowing with a dustpan bits;

(14) succinum: choose clean impurity, the used time smashs to pieces and is ground into fine powder;

(15) Semen sojae atricolor: choose clean impurity, dry;

(16) Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;

(17) Exocarpium Citri Rubrum: choose decontamination, outwash, used time folding is broken;

(18) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off ash bits, be kneaded into little group or cutting;

(19) Lumbricus: choose decontamination, water rinses, and pulls out in time, dries cutting;

(20) Radix Pseudostellariae: extract fibrous root, dry;

(21) Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;

(22) Massa Medicata Fermentata: get wheat bran and sprinkle evenly in heat pot, the cigarette of having waited, pours Massa Medicata Fermentata into, fries to yellow, takes out, and sieve removes wheat bran, cools;

(23) Oletum Trogopterori: choose clean impurity, smash or sieve dedust bits;

(24) Cortex Cinnamomi: choose clean impurity, the used time smashes, or scrape off rough bark, by warm water, infiltrating a moment, section, dries;

(25) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, clean, soften, shredding, dries or cold drying, sieve dedust bits;

(26) Lignum Santali Albi: be soaked in water, pound sheet or split brokenly, dries;

(27) Bulbus Allii Macrostemonis: choose decontamination, the sieve of winnowing with a dustpan goes whisker;

(28) Fructus Tribuli: float silt, the hard thorn that Ex-all is residual;

(29) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

(30) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

(31) Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, dry;

(32) Hirudo: clean, vexed soft, cutting, dries;

(33) Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;

(2) preparation

(1) by the Dens Draconis of described weight, Radix Et Rhizoma Nardostachyos, Fructus Jujubae, Folium Bambusae, Semen Platycladi, Herba Pyrolae, Rhizoma Zingiberis Recens, Lignum Dalbergiae Odoriferae, Fructus Schisandrae Chinensis, Herba Epimedii, Colla Corii Asini, Bulbus Lilii, Semen sojae atricolor, Radix Achyranthis Bidentatae, Exocarpium Citri Rubrum, Caulis Bambusae In Taenia, Lumbricus, Radix Pseudostellariae, Herba Ecliptae, Massa Medicata Fermentata, Oletum Trogopterori, Cortex Cinnamomi, Pericarpium Citri Reticulatae, Lignum Santali Albi, Bulbus Allii Macrostemonis, Fructus Tribuli, Poria, Radix Platycodonis, Radix Asparagi, Hirudo, Flos Chrysanthemi medicine, decoct with water, add for the first time 8 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 30 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time;

(2) will filter for the first time rear medicinal residues and add 6 times of amounts of water, and decoct boiling, then use slow fire boiling 40 minutes, filter to obtain decoction liquor for the second time;

(3) twice decoction liquor mixed, then use slow fire boiling 10 minutes, pour in container, add the Margarita powder of described weight and Succinum powder to stir, obtain medicinal liquid.