CN102293975B - Medicine for treating phthisis and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating phthisis, and a preparation method thereof. The medicine is mainly prepared from donkeyhide glue, natural indigo, flaccid aster herb, common bletilla pseudobulb, root of Szechwan-Yunnan sanicle, platycodon grandiflorus, ladybell root, Japanese metaplexis pericarp, stauntonvine and dwarf lilyturf tuber in a certain weight ratio. The medicine for treating phthisis can be prepared into any common oral formulation. The medicine has the effects of clearing heat and cooling blood, promoting pus discharge and regenerating tissue and invigorating the circulation of blood and removing blood stasis, a good effect of treating phthisis and quick response; and phthisis does not relapse.

Description

A kind of phthisical medicine and preparation method thereof for the treatment of

Technical field

The present invention relates to a kind of phthisical medicine for the treatment of, belong to the field of Chinese medicines.

Background technology

Pulmonary tuberculosis is commonly called as pulmonary tuberculosis, being to invade by tubercule bacillus the pulmonary infection that causes in human body, is also a kind of chronic and deferred infectious disease that youngster is easily suffered from, and 16-40 years old is the age occurred frequently lungy, all can fall ill throughout the year, after infecting, be 4-8 weeks incubation period.During outbreak, pale complexion, health is become thin, and violent cough seriously influences life and sleep, and western medical treatment is main mainly with antiinflammatory, antiviral Western medicine symptomatic treatment at present, but the doctor trained in Western medicine drug cost is high, and the course for the treatment of is long, and effect is undesirable.

Summary of the invention

Therefore people to curative effect preferably Chinese medicine have great demand, up to now, also do not find to the purpose of this invention is to provide about relevant report of the present invention the Chinese medicine composition that a kind of curative effect is treated pulmonary tuberculosis preferably.

Another object of the present invention just has been to provide the preparation method of this composition of medicine.

the present invention selects Colla Corii Asini, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis 30 seven flavor medicines make up, these drug regimens are made each drug regimen, make each efficacy of drugs produce synergism, thereby can effectively treat phthisical recurrence, wherein select Colla Corii Asini to be because its nature and flavor are sweet flat, enter lung, liver, kidney channel, nourishing YIN and supplementing blood is arranged, antiabortive function, control blood deficiency, cough due to consumptive disease, spit blood, epistaxis, have blood in stool, menoxenia, metrorrhagia, control leakage.Select the Radix Astragali to be because its nature and flavor are sweet, tepor enters lung, spleen channel, give birth to the useful consolidating superficial resistance of defending, and inducing diuresis to remove edema, poison holding, the function of granulation promoting is controlled spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and hold back for a long time; Process with the function that the invigorating middle warmer benefit is arranged, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Indigo Naturalis to be because its nature and flavor are salty, cold, enter liver, lung, stomach warp, heat clearing away is arranged, removing heat from blood, the function of detoxifcation is controlled the epidemic febrile disease intenseness of heat, and macule is spitted blood, is spat blood, Xiao Jing Epilepsy, skin ulcer is swollen, erysipelas, snake bite and insect sting.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, the loose stool of suffering from abdominal pain, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid is controlled the calentura excessive thirst, yin asthenia generating intrinsic heat, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis is sent out the speckle dermexanthesis.Select Herba Asteris Flaccidi to be because its nature and flavor are bitter, little suffering, cool has heat-clearing and toxic substances removing, and the function that cough-relieving makes eye bright is controlled lung abscess, pneumonia, pulmonary tuberculosis.Select Pseudobulbus Bletillae (Rhizoma Bletillae) to be because its property bitter but sweet flavor is cool, enter lung meridian, tonifying the lung is arranged, hemostasis, detumescence is given birth to and is seen, and the function of sore is controlled lung and is hindered hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, ulcer pain, the soup fire is burnt, rhagadia manus et pedis.Select Radix Asparagi to be because its nature and flavor sweetness and bitterness is cold, enter lung, kidney channel, YIN nourishing is arranged, moisturize, lung heat clearing, the function of pathogenic fire reducing is controlled fever due to yin deficiency, and cough is spitted blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain is quenched one's thirst, constipation.Select Folium Mori to be because its property bitter but sweet flavor is cold, enter lung, Liver Channel, expelling wind and clearing away heat is arranged, the function of cooling blood for improving eyesight, the dispelling the wind and dampness pathogens heating, headache, conjunctival congestion, thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Select Cortex Moutan to be because its nature and flavor are arduous, cool, enter the heart, liver, kidney channel, heat clearing away is arranged, removing heat from blood, and blood, the function of repercussive is controlled the pathogenic heat attacking blood system in febrile diseases, sends out speckle ， Jing Epilepsy, and tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer is flutterred damage.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae, enters lung, stomach, small intestine meridian, and removing heat from blood is arranged, hemostasis, and heat clearing away, the function of diuresis is controlled the calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, the meridian of Foot-TAI YIN edema caused by disorder of QI, invigorating the spleen and replenishing QI is arranged, the function of promoting the production of body fluid is controlled weakness of the spleen and stomach, deficiency of both QI and blood, and fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.Select the Rhizoma Pinelliae to be because its nature and flavor are hot, temperature, poisonous, enter spleen, stomach warp, drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass is controlled the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select Radix Gentianae to be because its nature and flavor are bitter, cold, enter liver, gallbladder meridian, the eliminating pathogen in the liver excess-fire is arranged, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the carbuncle skin infection, scrotum swells and ache, the pudendum pruritus due to damp pathogen.Selecting Radix Saniculae Astrantifoliae is because of its property sweet and slightly bitter taste, and the function of invigorating the lung and the kidney is arranged, and controls pulmonary tuberculosis, lumbago due to renal deficiency.Selecting Radix Dipsaci is that tepor enters liver, kidney channel, and invigorating the liver and kidney is arranged because of its nature and flavor toil, reuniting the fractured tendons and bones, and the function of blood circulation regulating is controlled aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, the carbuncle skin ulcer is swollen.Selecting the Radix Stemonae is that tepor enters lung meridian, and gentle lung qi is arranged because of its nature and flavor sweetness and bitterness, cough-relieving, and the function of parasite killing is controlled the cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.Select Radix Gentianae Macrophyllae to be because its nature and flavor toil is flat, enter liver, stomach, gallbladder meridian, expelling wind and removing dampness is arranged, and the blood Shujin, the function of clearing away heat and promoting diuresis, the dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture, jaundice is had blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Select Lignum Aquilariae Resinatum to be because its nature and flavor are arduous, temperature enters kidney, spleen, stomach warp, and the sending down the abnormal ascending QI warming middle-JIAO is arranged, and the function of warming the kidney improving inspiration by invigorating kidney-QI is controlled QI rising in reverse order and panted, vomiting singultus, abdominal distention, waist paint cold caused by deficiency, asthenia-cool of the large intestine, urine qi stranguria, man's cold sperm.Select Radix Platycodonis to be because its nature and flavor toil is flat, enter lung, stomach warp, lung qi dispersing gas is arranged out, the function of the evacuation of pus of eliminating the phlegm is controlled the exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Select Radix Scrophulariae to be because its nature and flavor are bitter, salty, cool, enter lung, kidney channel, YIN nourishing is arranged, pathogenic fire reducing, relieving restlessness, the function of detoxifcation is controlled the calentura excessive thirst, sends out speckle, and the hectic fever due to YIN-deficiency consumptive fever is slept not peaceful night, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Select Radix Stellariae to be because its nature and flavor sweetness and bitterness is cool, enter liver, stomach warp, the function of clearing away heat and cooling blood is arranged, control the asthenia hectic fever due to YIN-deficiency, deficiency of YIN chronic malaria, children's's infantile malnutrition with fever weakness and emaciation.Select Depositum urinae preparatum to be because its nature and flavor are salty, cold, enter lung, kidney channel, the function of nourishing YIN to lower pathogenic fire is arranged, control the hectic fever due to YIN-deficiency consumptive fever, cough, hemoptysis, laryngopharynx swelling and pain, the food regurgitation of choking, seminal emission, nebulousurine, stranguria marked by chyluria, women's leucorrhea with red and white discharge.Select Pericarpium Metaplexis to be because its nature and flavor are salty, put down, the function of removing heat from the lung and dissipating phlegm is arranged, control cough with copious phlegm, dyspnea and cough due to the lung-wind syndrome with phlegm, pertussis ， Jing Epilepsy, measles without adequate eruption.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, heat clearing away is arranged, removing heat from blood reduces phlegm, and the function of emesis is controlled dysphoria with smothery sensation vomiting, singultus, and the expectorant heat syndrome cough is breathed heavily, spit blood, and epistaxis, metrorrhagia, malignant histocytosis, fetal movement ， Jing Epilepsy.Select Cordyceps to be because its nature and flavor are sweet, temperature enters lung, kidney two warps, and tonifying deficiency is arranged, and the function of beneficial vital essence is controlled phlegm retention and breathed heavily and cough, dyspnea due to deficiency, and consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, prolonged deficiency is multiple after being ill.Select Radix Rehmanniae Preparata to be because its nature and flavor are sweet, tepor enters liver, kidney channel, and YIN nourishing is arranged, and the function of enriching blood is controlled deficiency of YIN insufficiency of blood, the waist knee flaccidity, and the chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia is quenched one's thirst, frequency of micturition, deafness, blurred vision.Select Concha Haliotidis to be because its nature and flavor are salty, flat, enter liver, kidney channel, suppressing the hyperactive liver and subsiding YANG is arranged, heat extraction, the function that makes eye bright is controlled wind-yang and up-boring, headache is dizzy, frightened jerking, hectic fever due to YIN-deficiency consumptive fever, optic atrophy.Select Bulbus Fritillariae Cirrhosae to be because its property bitter but sweet flavor is cool, enter lung meridian, the lung moistening eliminating stagnation is arranged, the function that antitussive reduces phlegm is controlled cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis.Select Radix Adenophorae to be because its nature and flavor are sweet, be slightly cold, attach to the lung and stomach meridians, nourishing YIN and clearing away lung-heat is arranged, reduce phlegm, the function of QI invigorating is controlled lung-heat type cough, deficiency of YIN phthisical cough, and dry cough expectorant is glutinous, deficiency of both vital energy and Yin, restlessness and fever with thirst.Select Poria to be because its property slightly sweet flavor is flat, enter the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria edema distending pain, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Selecting Radix Angelicae Sinensis is that temperature enters the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, nourishing blood to suppress the hyperactive liver is arranged, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Radix Et Rhizoma Rhei to be because its nature and flavor are bitter, cold, enter stomach, large intestine, liver footpath, the poison of purging heat is arranged, removing mass is stagnant, the function of clots absorbing blood is controlled the excess-heat constipation, and delirium is gone mad, the food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, the time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia is spitted blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge is urinated red, the carbuncle and ulcer toxic swelling, furuncle, burn.Select Fructus Schisandrae Chinensis to be because its nature and flavor are sour, temperature enters lung, kidney channel, astringes the lung, and nourishing kidney is promoted the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission is controlled the deficiency of the lung and breathed with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Select Caulis et folium stauntoniae to be because it has the function of heart tonifying, diuresis, pain relieving.Selecting Radix Ophiopogonis is because its property sweet and slightly bitter taste, cold, enters lung, stomach, heart channel, and nourishing YIN and moistening the lung is arranged, the relieving restlessness that clears away heart-fire, and the function of reinforcing stomach reg fluid is controlled dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation, clear thirsty, calentura Tianjin wound, dry mouth and throat, constipation.

The specific embodiment

Drug dose in the invention combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has curative effect preferably in the following weight scope.

Colla Corii Asini 10-20 gram Radix Astragali 10-20 gram Indigo Naturalis 10-15 grams

Radix Glycyrrhizae 6-10 gram Radix Rehmanniae 10-20 gram Herba Asteris Flaccidi 10-20 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 gram Radix Asparagi 8-12 gram Folium Mori 10-20 grams

Cortex Moutan 10-15 gram Rhizoma Imperatae 10-15 gram Radix Codonopsis 10-20 grams

The Rhizoma Pinelliae 10-15 cron gallbladder 8-12 gram Radix Saniculae Astrantifoliae 8-12 grams

Radix Dipsaci 10-20 gram Radix Stemonae 10-20 gram Radix Gentianae Macrophyllae 10-20 grams

Lignum Aquilariae Resinatum 8-12 gram Radix Platycodonis 10-15 gram Radix Scrophulariae 10-15 grams

Radix Stellariae 10-20 gram Depositum urinae preparatum 4-8 gram Pericarpium Metaplexis 8-12 grams

Caulis Bambusae In Taenia 8-12 gram Cordyceps 4-8 gram Radix Rehmanniae Preparata 8-12 grams

Concha Haliotidis 8-15 gram Bulbus Fritillariae Cirrhosae 8-15 gram Radix Adenophorae 10-20 grams

Poria 8-12 gram Radix Angelicae Sinensis 10-15 gram Radix Paeoniae Alba 10-15 grams

Radix Et Rhizoma Rhei 4-8 gram Fructus Schisandrae Chinensis 10-15 gram Caulis et folium stauntoniae 8-12 grams

Radix Ophiopogonis 8-12 grams

Be preferably

The Colla Corii Asini 15 gram Radix Astragali 15 gram Indigo Naturalis 12 grams

Radix Glycyrrhizae 8 gram Radix Rehmanniae 15 gram Herba Asteris Flaccidi 15 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 15 gram Radix Asparagi 10 gram Folium Mori 15 grams

Cortex Moutan 12 gram Rhizoma Imperatae 12 gram Radix Codonopsis 15 grams

The Rhizoma Pinelliae 12 cron gallbladder 10 gram Radix Saniculae Astrantifoliae 10 grams

The Radix Dipsaci 15 gram Radix Stemonae 15 gram Radix Gentianae Macrophyllae 15 grams

Lignum Aquilariae Resinatum 10 gram Radix Platycodonis 12 gram Radix Scrophulariae 12 grams

Radix Stellariae 15 gram Depositum urinae preparatum 6 gram Pericarpium Metaplexis 10 grams

Caulis Bambusae In Taenia 10 gram Cordyceps 6 gram Radix Rehmanniae Preparata 10 grams

Concha Haliotidis 12 gram Bulbus Fritillariae Cirrhosae 12 gram Radix Adenophorae 15 grams

The Poria 10 gram Radix Angelicae Sinensis 12 gram Radix Paeoniae Alba 12 grams

Radix Et Rhizoma Rhei 6 gram Fructus Schisandrae Chinensis 12 gram Caulis et folium stauntoniae 10 grams

Radix Ophiopogonis 10 grams

Preparation method of the present invention is as follows

One, get the raw materials ready

1, Colla Corii Asini: smash use to pieces;

2, the Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;

3, Indigo Naturalis: choose decontamination, cross sieve;

4, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly the time to eighty per cant, run through section, airing;

5, Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cut sheet, drying, and sieve removes chip;

6, Herba Asteris Flaccidi: all herbal medicine, Xia Qiu gathers, and dries in the shade;

7, Pseudobulbus Bletillae (Rhizoma Bletillae): choose decontamination, be soaked in water, pull out, dry in the air suitable to humidity, section, drying;

8, Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

9, Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;

10, Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;

11, Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

12, Radix Codonopsis: run through reed after cleaning silt, section or cutting are dried;

13, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;

14, Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;

15, Radix Saniculae Astrantifoliae: choose decontamination, moisten soft, the section, dry;

16, Radix Dipsaci: clean silt, remove the retained root head, run through rear section and dry, sieve anti-dandruff;

17, the Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;

18, Radix Gentianae Macrophyllae: choose decontamination, except removing LU, slightly soak, run through section, dry;

19, Lignum Aquilariae Resinatum: outwash, be split into fritter, fine powder is smashed or be ground into to the used time to pieces;

20, Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

21, Radix Scrophulariae: choose clean impurity, except removing LU, clean running through, section is dried;

22, Radix Stellariae: choose decontamination, go reed, wash, slightly soak and pull out, run through, section is dried;

23, Depositum urinae preparatum: remove impurity, break into fragment;

24, Pericarpium Metaplexis: cut off fruit stem, remove seed and floss hair;

25, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off the ash bits, be kneaded into little group or cutting

26, Cordyceps: remove impurity;

27, Radix Rehmanniae Preparata: get Radix Rehmanniae and add yellow wine 30%, mix thoroughly in steaming device, steam to inside and outside black profit, taking-up is dried;

28, Concha Haliotidis: clean and dry, the knock fragment;

29, Bulbus Fritillariae Cirrhosae: choose decontamination, be soaked in water, pull out, moistening is peelled off the heart, dries;

30, Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, drying;

31, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

32, Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening slightly dries in the air when suitable to inside and outside humidity, and section is dried;

33, the Radix Paeoniae Alba: choose roguing and sanction, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;

34, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

35, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

36, Caulis et folium stauntoniae: get rattan, the stem of Fructus Chaenomelis, remove impurity, soak, run through, section, drying;

37, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry.

Two, preparation

1, the preparation of decocting liquid

(1) with the Colla Corii Asini of described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water, adding for the first time water is 2 times of amounts of crude drug weight, intense fire decocts boiling 30 minutes, used again slow fire boiling 20 minutes, filter and namely get decoction liquor for the first time, for patient early taking liquid.

(2) medicinal residues after filtering for the first time add 1.5 times of amounts that water is medicinal residues weight, decoct boiling, then use slow fire boiling 20 minutes, filter and namely get decoction liquor for the second time, are the liquid of taking medicine patient's evening.

2, the preparation of capsule

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis adds decocting twice, each amount of water was for soaking powder, intense fire decocts boiling, slow fire boiling 20 minutes, merge decoction liquor twice, it is 1.35 extractum that filtering and concentrating becomes proportion, add 90-95% ethanol and carry out precipitate with ethanol, reclaim ethanol and be concentrated under 45-50 ℃ dry, it is ground into powder, incapsulate.

3, the preparation of tablet

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, adding for the first time water is 6 times of amounts of crude drug weight, decocted 1.5 hours, adding for the second time water is 4 times of amounts of crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, extractum is added 90-95% ethanol, stir, precipitation, reclaim ethanol and concentrated, and dry under 45-50 ℃, be ground into powder, add the adjuvant compacting in flakes.

4, the preparation of granule

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, adding for the first time water is 6 times of amounts of crude drug weight, decocted 1.5 hours, adding for the second time water is 4 times of amounts of crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, extractum is added 90-95% ethanol, stir, precipitation, reclaim ethanol and concentrated, dry under 45-50 ℃, add adjuvant, granulation.

5, the preparation of unguentum

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, adding for the first time water is 6 times of amounts of crude drug weight, decocted 1.5 hours, adding for the second time water is 4 times of amounts of crude drug, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum.

The active component of medicine of the present invention can add preparation required various conventional adjuvant during different dosage form, is prepared into any common peroral dosage form with the method for Chinese medicinal of routine, as tablet, capsule, granule, unguentum etc.

Medicine of the present invention has clearing away heat and cooling blood, the Activating stasis of blood, and the function of promoting pus discharge and tissue regeneration strengthening is used for the treatment of pulmonary tuberculosis, good effect, instant effect is difficult for recurrence.

Below further set forth the beneficial effect of medicine of the present invention by test example, these test examples comprise animal toxicity test and the clinical observation test of medicine of the present invention.

The animal toxicity test data of [test example 1] medicine of the present invention:

1, get 40 of new zealand rabbits, body weight 2.0-2.5kg, male and female dual-purpose are divided into two groups, and 20 every, wherein one group is the overdose test group, and another group is the normal amount test group.

2, the overdose group is 15ml/kg, and the normal amount group is 10ml%, and administering mode is the administration by gavage administration, and every day is secondary sooner or later, serve on a week, observes the administration reaction every day, and result shows that the movable diet of two groups of rabbit is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data:

Accept out-patient's 360 examples for medical treatment, 15-20 years old age, 30 examples, 21-30 years old 96 example, 31-40 years old 79 example, 41-50 years old 72 example, 83 examples more than 50 years old.

2, diagnostic criteria:

Light shape pulmonary tuberculosis: the light-duty pulmonary tuberculosis in 1 year of fall ill, patient's cough is spat blood, hectic fever, night sweat, restlessness and thirst is breathed hard and is breathed with cough.

Heavy shape pulmonary tuberculosis: medical history is more than 1 year, patient's cough, and sputum mixed with blood, expectorant matter is thick dense, osteopyrexia and fever, insomnia and dreamful sleep chokes that it is out of breath to cough, tugging pain over the chest and hypochondrium, red tongue, thready and rapid pulse.

3, Therapeutic Method:

Decocting liquid: every day twice, herbal decoction decocts and to take routinely, sooner or later services once, and 20 days is a course for the treatment of, course for the treatment of of light shape, heavy three courses for the treatment of.

Capsule: every day three times, each 12,20 days is a course for the treatment of, light-duty two courses for the treatment of, heavy three courses for the treatment of.

Tablet: every day three times, each 10,20 days is a course for the treatment of, light-duty two courses for the treatment of, reopens three courses for the treatment of.

Granule: every day three times, each two bags of 15g, 20 days is a course for the treatment of, light-duty two courses for the treatment of, heavy three courses for the treatment of.

4, efficacy assessment standard:

Produce effects: the degree type pulmonary tuberculosis after treatment, patient's transference cure, it is normal that patient's body constitution is recovered, and follows up a case by regular visits to 1-2 years without the recidivist.

Take a turn for the better: the degree type pulmonary tuberculosis is after treatment, and symptom obviously alleviates, and it is normal that patient's body constitution is recovered substantially.

Invalid: as not reach the improvement standard good.

5, therapeutic outcome: see the following form

In the treatment of two courses for the treatment of, with light-duty pulmonary tuberculosis 228 examples of Drug therapy of the present invention, produce effects 213 effects, total effective rate is 99.12%, in the treatment of three courses for the treatment of, with heavy pulmonary tuberculosis 132 examples of Drug therapy of the present invention, produce effects 112 examples, total effective rate is 95.45%.

Claims (3)

1. treat phthisical medicine for one kind, it is characterized in that: it is comprised of the crude drug in following weight range:

Colla Corii Asini 10-20 gram Radix Astragali 10-20 gram Indigo Naturalis 10-15 grams

Radix Glycyrrhizae 6-10 gram Radix Rehmanniae 10-20 gram Herba Asteris Flaccidi 10-20 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 10-20 gram Radix Asparagi 8-12 gram Folium Mori 10-20 grams

Cortex Moutan 10-15 gram Rhizoma Imperatae 10-15 gram Radix Codonopsis 10-20 grams

The Rhizoma Pinelliae 10-15 cron gallbladder 8-12 gram Radix Saniculae Astrantifoliae 8-12 grams

Radix Dipsaci 10-20 gram Radix Stemonae 10-20 gram Radix Gentianae Macrophyllae 10-20 grams

Lignum Aquilariae Resinatum 8-12 gram Radix Platycodonis 10-15 gram Radix Scrophulariae 10-15 grams

Radix Stellariae 10-20 gram Depositum urinae preparatum 4-8 gram Pericarpium Metaplexis 8-12 grams

Caulis Bambusae In Taenia 8-12 gram Cordyceps 4-8 gram Radix Rehmanniae Preparata 8-12 grams

Concha Haliotidis 8-15 gram Bulbus Fritillariae Cirrhosae 8-15 gram Radix Adenophorae 10-20 grams

Poria 8-12 gram Radix Angelicae Sinensis 10-15 gram Radix Paeoniae Alba 10-15 grams

Radix Et Rhizoma Rhei 4-8 gram Fructus Schisandrae Chinensis 10-15 gram Caulis et folium stauntoniae 8-12 grams

Radix Ophiopogonis 8-12 grams.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

The Colla Corii Asini 15 gram Radix Astragali 15 gram Indigo Naturalis 12 grams

Radix Glycyrrhizae 8 gram Radix Rehmanniae 15 gram Herba Asteris Flaccidi 15 grams

Pseudobulbus Bletillae (Rhizoma Bletillae) 15 gram Radix Asparagi 10 gram Folium Mori 15 grams

Cortex Moutan 12 gram Rhizoma Imperatae 12 gram Radix Codonopsis 15 grams

The Rhizoma Pinelliae 12 cron gallbladder 10 gram Radix Saniculae Astrantifoliae 10 grams

The Radix Dipsaci 15 gram Radix Stemonae 15 gram Radix Gentianae Macrophyllae 15 grams

Lignum Aquilariae Resinatum 10 gram Radix Platycodonis 12 gram Radix Scrophulariae 12 grams

Radix Stellariae 15 gram Depositum urinae preparatum 6 gram Pericarpium Metaplexis 10 grams

Caulis Bambusae In Taenia 10 gram Cordyceps 6 gram Radix Rehmanniae Preparata 10 grams

Concha Haliotidis 12 gram Bulbus Fritillariae Cirrhosae 12 gram Radix Adenophorae 15 grams

The Poria 10 gram Radix Angelicae Sinensis 12 gram Radix Paeoniae Alba 12 grams

Radix Et Rhizoma Rhei 6 gram Fructus Schisandrae Chinensis 12 gram Caulis et folium stauntoniae 10 grams

Radix Ophiopogonis 10 grams.

3. the preparation method of described medicine according to claim 1 and 2, it is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) Colla Corii Asini: smash use to pieces;

(2) Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;

(3) Indigo Naturalis: choose decontamination, cross sieve;

(4) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly the time to eighty per cant, run through section, airing;

(5) Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cut sheet, drying, and sieve removes chip;

(6) Herba Asteris Flaccidi: all herbal medicine, Xia Qiu gathers, and dries in the shade;

(7) Pseudobulbus Bletillae (Rhizoma Bletillae): choose decontamination, be soaked in water, pull out, dry in the air suitable to humidity, section, drying;

(8) Radix Asparagi: choose decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

(9) Folium Mori: choose decontamination, rub with the hands brokenly, winnow with a dustpan destemming, sieve removes spare;

(10) Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;

(11) Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

(12) Radix Codonopsis: run through reed after cleaning silt, section or cutting are dried;

(13) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;

(14) Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;

(15) Radix Saniculae Astrantifoliae: choose decontamination, moisten soft, the section, dry;

(16) Radix Dipsaci: clean silt, remove the retained root head, run through rear section and dry, sieve anti-dandruff;

(17) Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;

(18) Radix Gentianae Macrophyllae: choose decontamination, except removing LU, slightly soak, run through section, dry;

(19) Lignum Aquilariae Resinatum: outwash, be split into fritter, fine powder is smashed or be ground into to the used time to pieces;

(20) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;

(21) Radix Scrophulariae: choose clean impurity, except removing LU, clean running through, section is dried;

(22) Radix Stellariae: choose decontamination, go reed, wash, slightly soak and pull out, run through, section is dried;

(23) Depositum urinae preparatum: remove impurity, break into fragment;

(24) Pericarpium Metaplexis: cut off fruit stem, remove seed and floss hair;

(25) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shake off the ash bits, be kneaded into little group or cutting

(26) Cordyceps: remove impurity;

(27) Radix Rehmanniae Preparata: get Radix Rehmanniae and add yellow wine 30%, mix thoroughly in steaming device, steam to inside and outside black profit, taking-up is dried;

(28) Concha Haliotidis: clean and dry, the knock fragment;

(29) Bulbus Fritillariae Cirrhosae: choose decontamination, be soaked in water, pull out, moistening is peelled off the heart, dries;

(30) Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, drying;

(31) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;

(32) Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening slightly dries in the air when suitable to inside and outside humidity, and section is dried;

(33) Radix Paeoniae Alba: choose roguing and sanction, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;

(34) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

(35) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;

(36) Caulis et folium stauntoniae: get rattan, the stem of Fructus Chaenomelis, remove impurity, soak, run through, section, drying;

(37) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry;

(2) preparation

1, the preparation of decocting liquid

1. with the Colla Corii Asini of described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water, adding for the first time water is 2 times of amounts of crude drug weight, intense fire decocts boiling 30 minutes, used again slow fire boiling 20 minutes, filter and namely get decoction liquor for the first time, for patient early taking liquid,

2. the medicinal residues after filtering for the first time add 1.5 times of amounts that water is medicinal residues weight, decoct boiling, then use slow fire boiling 20 minutes, filter and namely get decoction liquor for the second time, are the liquid of taking medicine patient's evening;

(2) preparation of capsule

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis adds decocting twice, each amount of water was for soaking powder, intense fire decocts boiling, slow fire boiling 20 minutes, merge decoction liquor twice, it is 1.35 extractum that filtering and concentrating becomes proportion, add 90-95% ethanol and carry out precipitate with ethanol, reclaim ethanol and be concentrated under 45-50 ℃ dry, it is ground into powder, incapsulate,

(3) preparation of tablet

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, adding for the first time water is 6 times of amounts of crude drug weight, decocted 1.5 hours, adding for the second time water is 4 times of amounts of crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, extractum is added 90-95% ethanol, stir, precipitation, reclaim ethanol and concentrated, and dry under 45-50 ℃, be ground into powder, add the adjuvant compacting in flakes,

(4) preparation of granule

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, adding for the first time water is 6 times of amounts of crude drug weight, decocted 1.5 hours, adding for the second time water is 4 times of amounts of crude drug weight, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum, extractum is added 90-95% ethanol, stir, precipitation, reclaim ethanol and concentrated, dry under 45-50 ℃, add adjuvant, granulation,

(5) preparation of unguentum

Colla Corii Asini with described weight, the Radix Astragali, Indigo Naturalis, Radix Glycyrrhizae, Radix Rehmanniae, Herba Asteris Flaccidi, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Asparagi, Folium Mori, Cortex Moutan, Rhizoma Imperatae, Radix Codonopsis, the Rhizoma Pinelliae, Radix Gentianae, Radix Saniculae Astrantifoliae, Radix Dipsaci, the Radix Stemonae, Radix Gentianae Macrophyllae, Lignum Aquilariae Resinatum, Radix Platycodonis, Radix Scrophulariae, Radix Stellariae, Depositum urinae preparatum, Pericarpium Metaplexis, Caulis Bambusae In Taenia, Cordyceps, Radix Rehmanniae Preparata, Concha Haliotidis, Bulbus Fritillariae Cirrhosae, Radix Adenophorae, Poria, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Fructus Schisandrae Chinensis, Caulis et folium stauntoniae, Radix Ophiopogonis decocts with water twice, adding for the first time water is 6 times of amounts of crude drug weight, decocted 1.5 hours, adding for the second time water is 4 times of amounts of crude drug, decocted 1 hour, merging the secondary decoction liquor, to be condensed into proportion be 1.35 extractum.