CN103961566A - Medicament for treating hypertension and preparation method thereof - Google Patents
Medicament for treating hypertension and preparation method thereof Download PDFInfo
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- CN103961566A CN103961566A CN201410225789.0A CN201410225789A CN103961566A CN 103961566 A CN103961566 A CN 103961566A CN 201410225789 A CN201410225789 A CN 201410225789A CN 103961566 A CN103961566 A CN 103961566A
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Abstract
The invention discloses a medicament for treating hypertension and a preparation method thereof. The medicament is mainly prepared from coptis chinensis, radix paeoniae alba, unprocessed rehmannia root, medlar, radix polygonati officinalis, safflower, ligusticum, fructus viticis, inula flower and other medicinal materials in a certain weight ratio, has the functions of clearing heat and cooling blood, reducing hypertension and activating blood circulation, and has the advantages of quick response, good curative effect and relapse prevention when being used for treating hypertension.
Description
Technical field
The present invention relates to one and treat hypertensive medicine and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Hypertension (hypertension) is one of modal disease of the mankind, to increase the independent disease as main clinical manifestation taking arteriotony, the cause of disease is not yet very clear and definite, there is certain relation with age, occupation, family history, clinical essential hypertension and the secondary hypertension of being divided into, dizzy is one of its primary symptom.Because Western medicine cannot effectively be treated hypertension, there is great demand to the hypertensive Chinese medicine of rapid, effective treatment in people therefore, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the hypertensive medicine of effective treatment, thereby has completed the present invention.
Object of the present invention is just to provide the hypertensive Chinese medicine composition of a kind of more effective treatment.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Rhizoma Coptidis, Radix Paeoniae Alba, Radix Rehmanniae, Fructus Lycii, Rhizoma Polygonati Odorati, Flos Carthami, Rhizoma Ligustici, Fructus Viticis, Ramulus Uncariae Cum Uncis, Concha Haliotidis, Folium Ilicis, Semen Celosiae, Radix Gentianae, Radix Scrophulariae, Herba Apocyni veneti, Rhizoma Gastrodiae, Herba Leonuri, Flos Inulae, Herba Taxilli, Spica Prunellae, Flos Sophorae, Flos Chrysanthemi, Radix Ilicis Pubescentis, the Cortex Eucommiae, Fructus Schisandrae Chinensis, Concha Ostreae, Radix Achyranthis Bidentatae, Gypsum Fibrosum, Concha Margaritifera, Halloysitum Rubrum medicine to combine preparation, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat hypertension.Wherein select Rhizoma Coptidis to be because its nature and flavor hardship is cold, enter the heart, liver, stomach, large intestine channel, have pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever while controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis, tells, nosebleed, hematochezia, quenches one's thirst, and infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid, controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, sends out speckle dermexanthesis.Select Fructus Lycii to be because its nature and flavor are sweet, flat, there is nourishing kidney, lung moistening, tonifying liver, the function of improving eyesight, controls hepatic and renal YIN deficiency, and soreness of the waist and knees is had a dizzy spell, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, and loses clear.Sweet because of its nature and flavor with Rhizoma Polygonati Odorati, flat, enter lung, stomach warp, has yin nourishing, moisturizes, relieving restlessness, the function of quenching the thirst, controls calentura sun wound, cough, excessive thirst, deficient fever, rapid digestion of food is famine easily, frequent micturition.Select Flos Carthami to be because its nature and flavor are pungent, temperature, enters the heart, Liver Channel, has promoting blood circulation to restore menstrual flow, and the function of blood stasis removing pain relieving is controlled amenorrhea ， mass in the abdomen, difficult labour, and stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Rhizoma Ligustici to be because its nature and flavor are pungent, temperature, returns urinary bladder channel, has cold expelling to dispel the wind, the function of removing damp and stopping pain, and for anemofrigid cold, top, mountain peak pain.Selecting Fructus Viticis is because its nature and flavor toil, cool, enters liver, stomach, and urinary bladder channel, has dispelling wind and heat pathogens, and the clear sharp head's function, controls anemopyretic cold, just, migraine, and toothache, pain in order eyeball.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor hardship is cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, and adult's blood pressure is higher, dizzy, dizzy, married woman's eclampsia.Select Concha Haliotidis to be because its nature and flavor are salty, flat, enter liver, kidney channel, there is suppressing the hyperactive liver and subsiding YANG, heat extraction, the function of improving eyesight, controls wind-yang and up-boring, has a headache dizzy, frightened jerking, hectic fever due to YIN-deficiency consumptive fever, optic atrophy.Select Folium Ilicis to be because its property bitter but sweet flavor in Great Cold, enters liver, lung, stomach warp, have loose wind heat, refresh oneself, the function of relieving thirst and restlessness, controls headache, toothache, conjunctival congestion, Ting ear, calentura excessive thirst, dysentery.Select Semen Celosiae to be because its nature and flavor hardship is cool, enter Liver Channel, the heat of dispeling the wind, the function of clearing away liver-fire, controls conjunctival congestion and swelling pain, hides from view, hypertension, epistaxis, skin wind heat pruritus, mange.Select Radix Gentianae to be because its nature and flavor hardship is cold, enter liver, gallbladder meridian, have eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B, and headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.Select Radix Scrophulariae to be because its nature and flavor hardship is salty, cool, enter lung, kidney channel, have YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances, controls calentura excessive thirst, sends out speckle, and hectic fever due to YIN-deficiency consumptive fever, sleeps not peaceful night, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Select Herba Apocyni veneti to be because its nature and flavor sweetness and bitterness is cool, relieve inflammation or internal heat, blood pressure lowering, heart tonifying, the function of diuresis, controls heart disease, hypertension, neurasthenia, hepatitis abdominal distention, floating kind of nephritis.Select Rhizoma Gastrodiae to be because its nature and flavor are sweet, flat, enter Liver Channel, there is endogenous wind stopping, the function of arresting convulsion, controls dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia, aphasia, little Jing Epilepsy wind symptom.Select Herba Leonuri to be because its nature and flavor are arduous, cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears, controls menoxenia, controls Lou difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria, rushes down blood, carbuncle skin infection.Select Flos Inulae to be because its nature and flavor are salty, temperature, enters lung, liver, stomach warp, has expectorant, the therapeutic method to keep the adverse QI flowing downwards, and softening the hard mass, the function of row water, controls in the heart expectorant knot, the lower distension of the side of body, cough with asthma, singultus, saliva is as shellac varnish, epigastric oppression and rigidity, eructation unrelieved, extensive abdominal edema.Select Herba Taxilli to be because its property bitter but sweet flavor is flat, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive function, controls soreness of waist and knee joint, a little less than muscles and bones flaccidity, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Select Spica Prunellae to be because its nature and flavor toil is cold, enter liver, gallbladder meridian, have liver heat removing, the function of eliminating stagnation, controls scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Select Flos Sophorae to be because its nature and flavor hardship is cool, enter liver, large intestine channel, have heat clearing away, removing heat from blood, the function of hemostasis, controls discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis, under dysentery with red and white feces, wind heat conjunctival congestion, skin sore, and for prevention of stroke.Select Flos Chrysanthemi to be because its nature and flavor sweetness and bitterness is cool, enter lung, Liver Channel, has dispelling wind, the heat that disappears, and improving eyesight, the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Select Radix Ilicis Pubescentis to be because its property mildly bitter flavor is sweet, property is flat, nontoxic, have heat-clearing and toxic substances removing, the function of blood circulation and channel invigorating, controls anemopyretic cold, dyspnea and cough due to lung-heat, laryngeal edema, tonsillitis, dysentery, coronary heart disease, the hemiplegia due to cerebrovascular accident, thromboangiitis obliterans, erysipelas, scalds, central serous chorioretinopathy, uveitis, and skin acute suppurative inflammation.Select the Cortex Eucommiae to be because its nature and flavor are sweet micro-pungent, temperature, enters liver, kidney channel, has invigorating the liver and kidney, bone and muscle strengthening, and antiabortive function, controls spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, hypertension.Selecting Fructus Schisandrae Chinensis is that temperature, enters lung, kidney channel, astringes the lung because of its nature and flavor acid, and nourishing kidney, promotes the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduces phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and the function of subduing inflammation, controls gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe in invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select Gypsum Fibrosum to be because its property acrid-sweet flavor is cold, enter lung, stomach warp, raw with there being expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst, controls calentura high fever and does not move back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, forges deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, bursts and does not regain, the burning hot wound of soup.Select Concha Margaritifera to be because its nature and flavor are salty, cool, enter the heart, liver two warps, have suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, the function of hemostasis, controls dizziness, tinnitus, cardiopalmus, insomnia, demented ， Jing Epilepsy, spits blood, epistaxis, metrorrhagia.Selecting Halloysitum Rubrum is because of its property sweet-puckery flavor, temperature.Enter spleen, stomach, large intestine channel.Astringing intestine to stop diarrhea, hemostasis, removing dampness, effect of granulation promoting.Control chronic diarrhea, chronic dysentery, has blood in stool, proctoptosis, seminal emission, metrorrhagia, leukorrhagia, ulcer being unable to heal.
Detailed description of the invention
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Rhizoma Coptidis 5-10g Radix Paeoniae Alba 6-15g Radix Rehmanniae 10-18g
Fructus Lycii 8-16g Rhizoma Polygonati Odorati 15-25g Flos Carthami 5-15g
Rhizoma Ligustici 10-20g Fructus Viticis 5-15g Ramulus Uncariae Cum Uncis 15-25g
Concha Haliotidis 15-22g Folium Ilicis 6-15g Semen Celosiae 10-20g
Radix Gentianae 10-20g Radix Scrophulariae 15-25g Herba Apocyni veneti 10-20g
Rhizoma Gastrodiae 8-16g Herba Leonuri 5-15g Flos Inulae 10-20g
Herba Taxilli 10-20g Spica Prunellae 5-15g Flos Sophorae 10-20g
Flos Chrysanthemi 12-22g Radix Ilicis Pubescentis 15-25g Cortex Eucommiae 10-20g
Fructus Schisandrae Chinensis 15-25g Concha Ostreae 12-22g Radix Achyranthis Bidentatae 5-15g
Gypsum Fibrosum 5-12g Concha Margaritifera 18-26g Halloysitum Rubrum 10-20g.
Be preferably:
Rhizoma Coptidis 9g Radix Paeoniae Alba 6g Radix Rehmanniae 12g
Fructus Lycii 10g Rhizoma Polygonati Odorati 20g Flos Carthami 9g
Rhizoma Ligustici 12g Fructus Viticis 7g Ramulus Uncariae Cum Uncis 18g
Concha Haliotidis 20g Folium Ilicis 9g Semen Celosiae 15g
Radix Gentianae 15g Radix Scrophulariae 20g Herba Apocyni veneti 15g
Rhizoma Gastrodiae 10g Herba Leonuri 9g Flos Inulae 15g
Herba Taxilli 15g Spica Prunellae 10g Flos Sophorae 15g
Flos Chrysanthemi 15g Radix Ilicis Pubescentis 20g Cortex Eucommiae 12g
Fructus Schisandrae Chinensis 20g Concha Ostreae 20g Radix Achyranthis Bidentatae 10g
Gypsum Fibrosum 6g Concha Margaritifera 20g Halloysitum Rubrum 12g.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dries in the shade;
2, Radix Paeoniae Alba: choose decontamination, separately size, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
3, Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
4, Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;
5, Rhizoma Polygonati Odorati: remove impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;
6, Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
7, Rhizoma Ligustici: get crude drug, remove impurity, big or small stepping, wash quickly is clean, runs through, and section, dries;
8, Fructus Viticis: well sifted ash bits, remove remaining sepal, put in pot and fry with high heat to coke yellow, slightly spray clear water, cool;
9, Ramulus Uncariae Cum Uncis: choose old stalk, impurity, clean, dry;
10, Concha Haliotidis: clean and dry, knock fragment;
11, Folium Ilicis: remove residual branch stalk, impurity, dry;
12, Semen Celosiae: the 8-10 month gathers, extracts aerial parts or spica, rubs with the hands and removes seed, removes impurity, dries;
13, Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
14, Radix Scrophulariae: choose clean impurity, except removing LU, clean and run through, section, dries;
15, Herba Apocyni veneti: remove impurity, cleaning, drying;
16, Rhizoma Gastrodiae: choose decontamination, big or small stepping, is soaked in water to seventy percent saturating, pulls out, slightly dries in the air, then moistens to internal and external temperature evenly, and section, dries;
17, Herba Leonuri: choose decontamination, clean, run through, cutting, dries;
18, Flos Inulae: choose clean impurity, except destemming leaf, sieve removes earth;
19, Herba Taxilli: wash, run through, cutting, dries;
20, Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
21, Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
22, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
23, Radix Ilicis Pubescentis: summer, Qiu Cai, section is dried;
24, the Cortex Eucommiae: remove rough bark, clean, run through, dice or strand, dry;
25, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
26, Concha Ostreae: clean, dry, pulverize use;
27, Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
28, Gypsum Fibrosum: remove assorted stone, clean earth, be broken into fritter;
29, Concha Margaritifera: choose decontamination, knock fragment, sieve dedust bits;
30, Halloysitum Rubrum: choose earth, impurity.
Two, preparation
1, the Rhizoma Coptidis of described weight, Radix Paeoniae Alba, Radix Rehmanniae, Fructus Lycii, Rhizoma Polygonati Odorati, Flos Carthami, Rhizoma Ligustici, Fructus Viticis, Ramulus Uncariae Cum Uncis, Concha Haliotidis, Folium Ilicis, Semen Celosiae, Radix Gentianae, Radix Scrophulariae, Herba Apocyni veneti, Rhizoma Gastrodiae, Herba Leonuri, Flos Inulae, Herba Taxilli, Spica Prunellae, Flos Sophorae, Flos Chrysanthemi, Radix Ilicis Pubescentis, the Cortex Eucommiae, Fructus Schisandrae Chinensis, Concha Ostreae, Radix Achyranthis Bidentatae, Gypsum Fibrosum, Concha Margaritifera, Halloysitum Rubrum are decocted with water twice, 6 times of amounts for the first time add water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time.
2, the medicinal residues after filtering are for the first time added water 4 times and measured, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time.
3, merge twice decoction liquor, intense fire boils, then with slow fire boiling 10 minutes and get final product, medicinal liquid is divided into 4 doses and takes.
Medicine of the present invention has the function of clearing away heat and cooling blood, suppressing the hyperactive liver and subsiding YANG, is used for the treatment of hypertension instant effect, good effect.Further set forth below the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit activities, diet are normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 300 examples for medical treatment.
2, diagnostic criteria
At present domestic hypertensive diagnosis adopts the standard of Chinese Treatment Guidelines for Hypertension suggestion in 2000:
Classification systolic pressure (mmHg) diastolic pressure (mmHg)
Normal arterial pressure <120 <80
Normal high value 120～139 80～89
Hypertension >=140 >=90
1 grade of hypertension (slightly) 140～159 90～99
2 grades of hypertension (moderate) 160～179 100～109
3 grades of hypertension (severe) >=180 >=110
While adhering to different ranks separately as patient's systolic pressure and diastolic pressure, be as the criterion with higher grade scale.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, every day 2 times, each 1 dose 10 days is a course for the treatment of, takes continuously three courses for the treatment of.
4, efficacy assessment standard
Effective: the hypertension state of an illness is controlled, recover normal;
Take a turn for the better: hypertension pathological changes symptom alleviates, and patient sign improves, and the state of an illness progressively takes a turn for the better;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by 1 grade of hyperpietic's 100 example of Drug therapy of the present invention, effective 83 examples of result, obvious effective rate is 83%, 12 examples that take a turn for the better, and improvement rate is 12%, invalid 5 examples, total effective rate is 95%; Treat 2 grades of hyperpietic's 100 examples, effective 79 examples of result, obvious effective rate is 79%, 14 examples that take a turn for the better, improvement rate is 14%, invalid 7 examples, total effective rate is 93%; Treat 3 grades of hyperpietic's 100 examples, effective 76 examples of result, obvious effective rate is 76%, 15 examples that take a turn for the better, improvement rate is 15%, no effect 9, total effective rate is 91%.
Claims (3)
1. the hypertensive medicine for the treatment of, is characterized in that: it is to be made up of the crude drug in following weight range:
Rhizoma Coptidis 5-10g Radix Paeoniae Alba 6-15g Radix Rehmanniae 10-18g
Fructus Lycii 8-16g Rhizoma Polygonati Odorati 15-25g Flos Carthami 5-15g
Rhizoma Ligustici 10-20g Fructus Viticis 5-15g Ramulus Uncariae Cum Uncis 15-25g
Concha Haliotidis 15-22g Folium Ilicis 6-15g Semen Celosiae 10-20g
Radix Gentianae 10-20g Radix Scrophulariae 15-25g Herba Apocyni veneti 10-20g
Rhizoma Gastrodiae 8-16g Herba Leonuri 5-15g Flos Inulae 10-20g
Herba Taxilli 10-20g Spica Prunellae 5-15g Flos Sophorae 10-20g
Flos Chrysanthemi 12-22g Radix Ilicis Pubescentis 15-25g Cortex Eucommiae 10-20g
Fructus Schisandrae Chinensis 15-25g Concha Ostreae 12-22g Radix Achyranthis Bidentatae 5-15g
Gypsum Fibrosum 5-12g Concha Margaritifera 18-26g Halloysitum Rubrum 10-20g.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Rhizoma Coptidis 9g Radix Paeoniae Alba 6g Radix Rehmanniae 12g
Fructus Lycii 10g Rhizoma Polygonati Odorati 20g Flos Carthami 9g
Rhizoma Ligustici 12g Fructus Viticis 7g Ramulus Uncariae Cum Uncis 18g
Concha Haliotidis 20g Folium Ilicis 9g Semen Celosiae 15g
Radix Gentianae 15g Radix Scrophulariae 20g Herba Apocyni veneti 15g
Rhizoma Gastrodiae 10g Herba Leonuri 9g Flos Inulae 15g
Herba Taxilli 15g Spica Prunellae 10g Flos Sophorae 15g
Flos Chrysanthemi 15g Radix Ilicis Pubescentis 20g Cortex Eucommiae 12g
Fructus Schisandrae Chinensis 20g Concha Ostreae 20g Radix Achyranthis Bidentatae 10g
Gypsum Fibrosum 6g Concha Margaritifera 20g Halloysitum Rubrum 12g.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dries in the shade;
(2) Radix Paeoniae Alba: choose decontamination, separately size, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(3) Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
(4) Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;
(5) Rhizoma Polygonati Odorati: remove impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;
(6) Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
(7) Rhizoma Ligustici: get crude drug, remove impurity, big or small stepping, wash quickly is clean, runs through, and section, dries;
(8) Fructus Viticis: well sifted ash bits, remove remaining sepal, put in pot and fry with high heat to coke yellow, slightly spray clear water, cool;
(9) Ramulus Uncariae Cum Uncis: choose old stalk, impurity, clean, dry;
(10) Concha Haliotidis: clean and dry, knock fragment;
(11) Folium Ilicis: remove residual branch stalk, impurity, dry;
(12) Semen Celosiae: the 8-10 month gathers, extracts aerial parts or spica, rubs with the hands and removes seed, removes impurity, dries;
(13) Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
(14) Radix Scrophulariae: choose clean impurity, except removing LU, clean and run through, section, dries;
(15) Herba Apocyni veneti: remove impurity, cleaning, drying;
(16) Rhizoma Gastrodiae: choose decontamination, big or small stepping, is soaked in water to seventy percent saturating, pulls out, slightly dries in the air, then moistens to internal and external temperature evenly, and section, dries;
(17) Herba Leonuri: choose decontamination, clean, run through, cutting, dries;
(18) Flos Inulae: choose clean impurity, except destemming leaf, sieve removes earth;
(19) Herba Taxilli: wash, run through, cutting, dries;
(20) Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
(21) Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
(22) Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
(23) Radix Ilicis Pubescentis: summer, Qiu Cai, section is dried;
(24) Cortex Eucommiae: remove rough bark, clean, run through, dice or strand, dry;
(25) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
(26) Concha Ostreae: clean, dry, pulverize use;
(27) Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
(28) Gypsum Fibrosum: remove assorted stone, clean earth, be broken into fritter;
(29) Concha Margaritifera: choose decontamination, knock fragment, sieve dedust bits;
(30) Halloysitum Rubrum: choose earth, impurity;
(2) preparation
(1) Rhizoma Coptidis of described weight, Radix Paeoniae Alba, Radix Rehmanniae, Fructus Lycii, Rhizoma Polygonati Odorati, Flos Carthami, Rhizoma Ligustici, Fructus Viticis, Ramulus Uncariae Cum Uncis, Concha Haliotidis, Folium Ilicis, Semen Celosiae, Radix Gentianae, Radix Scrophulariae, Herba Apocyni veneti, Rhizoma Gastrodiae, Herba Leonuri, Flos Inulae, Herba Taxilli, Spica Prunellae, Flos Sophorae, Flos Chrysanthemi, Radix Ilicis Pubescentis, the Cortex Eucommiae, Fructus Schisandrae Chinensis, Concha Ostreae, Radix Achyranthis Bidentatae, Gypsum Fibrosum, Concha Margaritifera, Halloysitum Rubrum are decocted with water twice, 6 times of amounts for the first time add water, intense fire decocts boiling 10 minutes, use again slow fire boiling 25 minutes, filter to obtain decoction liquor for the first time;
(2) medicinal residues after filtering are for the first time added water 4 times and measured, intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time;
(3) merge twice decoction liquor, intense fire boils, then with slow fire boiling 10 minutes and get final product, is divided into 4 doses and takes.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107029122A (en) * | 2017-03-16 | 2017-08-11 | 杨本雷 | It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application |
| CN107441359A (en) * | 2017-08-14 | 2017-12-08 | 张素花 | A kind of medicine for treating hypertension and preparation method thereof |
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| CN1352983A (en) * | 2001-11-23 | 2002-06-12 | 郑国芃 | Chinese medicine for treating hypertension |
| CN101455792A (en) * | 2008-11-27 | 2009-06-17 | 朱新华 | Medicine capable of quickly treating hypertension |
| CN103751566A (en) * | 2013-12-24 | 2014-04-30 | 申天顺 | Traditional Chinese medicinal prescription for treating hypertension |
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| CN1352983A (en) * | 2001-11-23 | 2002-06-12 | 郑国芃 | Chinese medicine for treating hypertension |
| CN101455792A (en) * | 2008-11-27 | 2009-06-17 | 朱新华 | Medicine capable of quickly treating hypertension |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107029122A (en) * | 2017-03-16 | 2017-08-11 | 杨本雷 | It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application |
| CN107029122B (en) * | 2017-03-16 | 2018-05-01 | 杨本雷 | A kind of pharmaceutical composition for treating hypertension and preparation method thereof, preparation and application |
| CN107029122B8 (en) * | 2017-03-16 | 2024-06-11 | 楚雄彝族自治州彝族医药研究所 | Medicinal composition for treating hypertension and preparation method, preparation and application thereof |
| CN107441359A (en) * | 2017-08-14 | 2017-12-08 | 张素花 | A kind of medicine for treating hypertension and preparation method thereof |
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Application publication date: 20140806 |