CN102293964B - Medicine for treating gastric ulcer, and preparation method thereof - Google Patents

Medicine for treating gastric ulcer, and preparation method thereof Download PDF

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CN102293964B
CN102293964B CN2011102559331A CN201110255933A CN102293964B CN 102293964 B CN102293964 B CN 102293964B CN 2011102559331 A CN2011102559331 A CN 2011102559331A CN 201110255933 A CN201110255933 A CN 201110255933A CN 102293964 B CN102293964 B CN 102293964B
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孙桂侠
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Abstract

The invention discloses a medicine for treating gastric ulcer, and a preparation method thereof. The medicine is mainly prepared from atractylodes lancea, officinal magnolia bark, tangerine peel, liquorice, trogopterus dung, cattail pollen, ginseng, root of red-rooted salvia, Chinese yam, coix seed, ark shell, costustoot, sinkiang arnebia root, rhizoma atractylodis macrocephalae, white paeony root, Chinese angelica, bitter orange, dwarf lilyturf tuber, pinellia ternata and astragalus in a certain weight ratio. The medicine has the effects of tonifying spleen and qi, strengthening stomach, clearing liver-fire and eliminating heat, invigorating the circulation of blood and removing blood stasis, nourishing stomach yin, restraining acid, clearing way heat and toxic materials, and invigorating the circulation of blood to relieve pain, has quick response in treatment of gastric ulcer, and is short in a treatment course; and gastric ulcer does not relapse.

Description

A kind of medicine for the treatment of gastric ulcer and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of gastric ulcer and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Gastric ulcer is the digestive system common disease, and its typical case shows as hungry discomfort, glutted belch, pantothenic acid or regularly chronic middle Upper abdominal pain after the meal, when serious, melena and hematemesis can be arranged.The apparent in view cause of disease is helicobacter pylori infections and gastroxia; Can also be caused by factors such as inherited genetic factors and anxious state of mind, overworked, drinking and eating irregularly, smoking, excessive drinkings in addition.Gastric ulcer is because the state of an illness is prolonged silk floss, and the state of an illness is complicated, and is relevant with spiritual emotion again, and aggravation or treat untimelyly also can cause the ill effects such as hemorrhage, perforation, pyloric obstruction and canceration, the serious harm people ' s health.Aspect western medical treatment, can't resolve all the time curative effect slowly and two low difficult problems of improvement rate at present.
Summary of the invention
Therefore there is great demand in people to the Chinese medicine of special effect.The inventor has finally found the medicine of fast treating gastric ulcer, thereby has completed the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.
Purpose of the present invention just is to provide a kind of composition of medicine for the treatment of gastric ulcer.
Another object of the present invention just has been to provide the preparation method of this composition of medicine.
Medicament selection Rhizoma Atractylodis of the present invention, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Oletum Trogopterori, Pollen Typhae, Radix Ginseng, Radix Salviae Miltiorrhizae, Rhizoma Dioscoreae, Semen Coicis, Concha Arcae, the Radix Aucklandiae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Angelicae Sinensis, Fructus Aurantii, Radix Ophiopogonis, the Rhizoma Pinelliae, Radix Astragali medicine make up, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can the fast treating gastric ulcer.Wherein select Rhizoma Atractylodis to be because its nature and flavor are arduous, temperature enters spleen, stomach warp, and spleen invigorating is arranged, dampness, and resolving depression is warded off dirty function, control the wet tired spleen of containing, the asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting is had loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Selecting Cortex Magnoliae Officinalis is that temperature enters spleen, stomach, large intestine channel, and warming middle-JIAO is arranged because of its nature and flavor toil, the therapeutic method to keep the adverse QI flowing downwards, and dampness, the function of expectorant is controlled breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, the cold-damp dysentery.Select Pericarpium Citri Reticulatae to be because its nature and flavor are bitter, hot, temperature is returned lung, spleen channel, and regulating qi-flowing for strengthening spleen is arranged, and the function of drying dampness to eliminate phlegm is controlled fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, the loose stool of suffering from abdominal pain, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Selecting Oletum Trogopterori is that temperature enters liver, spleen channel because of its property bitter but sweet flavor, gives birth to the function that the promoting the circulation of blood pain relieving is arranged, and controls all pains of trusted subordinate's vim and vigour, women's amenorrhea, and postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite are fried with hemostasis, control metrorrhagia, menorrhagia, and leucorrhea with bloody discharge is without cease.Select Pollen Typhae to be because its nature and flavor are sweet arduous, cool, enter liver, heart channel, cooling blood for hemostasis is arranged, the function of activating blood circulation and dissipating blood stasis is given birth to controlling amenorrhea and is suffered from abdominal pain, and postpartum stagnation is had a pain, and falls that to flutter blood vexed, the furuncle toxic swelling is fried black emesis blood, epistaxis, metrorrhagia, rush down blood, hematuria, dysentery, leukorrhagia, external treatment congenital deformity of the tongue, aphtha, the Ting discharging ear, hemorrhage in ear, uncontrolled urination is itched.Select Radix Ginseng to be because its nature and flavor are sweet little sweet, temperature enters spleen, lung meridian, and strongly invigorating primordial QI is arranged, promote the production of body fluid admittedly take off, the function of calming the nerves is controlled impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, the stool lingering diarrhea, empty cough with asthma is short, the spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Select Radix Salviae Miltiorrhizae to be because its nature and flavor are bitter, tepor enters the heart, Liver Channel, and blood circulation and promoting silt is arranged, calming heart and tranquilizing mind, and evacuation of pus, the function of pain relieving is controlled angina cordis, menoxenia, dysmenorrhea, to close, metrorrhagia leukorrhagia , mass in the abdomen gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Rhizoma Dioscoreae to be because its property bitter but sweet flavor is flat, enter lung, spleen, kidney channel, spleen invigorating is arranged, tonifying the lung is reinforced the kidney, and the function of benefit essence is controlled diarrhea due to hypofunction of the spleen, chronic dysentery, and cough due to consumptive disease is quenched one's thirst, seminal emission, leukorrhagia, frequent micturition.Select Semen Coicis to be because its property slightly sweet flavor is cool, enter spleen, lung, kidney channel, spleen invigorating is arranged, tonifying the lung, heat clearing away, the function of dampness removing is controlled and is had loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.Select Concha Arcae to be because its nature and flavor are sweet, salty, flat, enter liver, spleen channel, have and reduce phlegm, softening the hard mass, dissipating blood stasis, the function of removing food stagnancy is controlled accumulation of phlegm, and stomachache is noisy, acid regurgitation , mass in the abdomen, scrofula, ulcerative gingivitis.Select the Radix Aucklandiae to be because its nature and flavor are arduous, temperature enters lung, liver, spleen channel, and promoting the circulation of QI to relieve pain are arranged, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and vomiting is had loose bowels, dysentery tenesmus, colic of cold type.Select Radix Arnebiae (Radix Lithospermi) to be because its nature and flavor earnestly, cold, enter percardium, Liver Channel, removing heat from blood is arranged, invigorate blood circulation, the function of heat-clearing and toxic substances removing is controlled warm macule, jaundice due to damp-heat, purpura tells, nosebleed, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature enters spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, nourishing blood to suppress the hyperactive liver is arranged, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Selecting Radix Angelicae Sinensis is that temperature enters the heart, liver, spleen channel, and benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation because of the sweet suffering of its nature and flavor, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Selecting Fructus Aurantii is because its nature and flavor toil, cool, enters lung, spleen, large intestine channel, and dispelling the stagnated QI is arranged, row expectorant, the function of removing food stagnancy is controlled chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, weight after dysentery, proctoptosis, uterine prolapse.Selecting Radix Ophiopogonis, have another name called Radix Ophiopogonis, is because its property sweet and slightly bitter taste is cold, enters lung, stomach, heart channel, and nourishing YIN and moistening the lung is arranged, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid is controlled dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation, clear thirsty, calentura Tianjin wound, dry mouth and throat, constipation.Select the Rhizoma Pinelliae to be because its nature and flavor are hot, temperature, poisonous, enter spleen, stomach warp, drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass is controlled the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select the Radix Astragali to be because its nature and flavor are sweet, tepor enters lung, spleen channel, give birth to the useful consolidating superficial resistance of defending, and inducing diuresis to remove edema, poison holding, the function of granulation promoting is controlled spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and hold back for a long time; Process with the function that the invigorating middle warmer benefit is arranged, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.
The specific embodiment
The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each grouping all has good therapeutic effect in the following weight scope:
Rhizoma Atractylodis 5-15 gram Cortex Magnoliae Officinalis 5-15 gram Pericarpium Citri Reticulatae 5-15 grams
Radix Glycyrrhizae 7-11 gram Oletum Trogopterori 5-15 gram Pollen Typhae 5-15 grams
Radix Ginseng 10-15 gram Radix Salviae Miltiorrhizae 10-20 Keshan medicine 10-20 grams
Semen Coicis 10-20 gram Concha Arcae 10-20 gram Radix Aucklandiae 5-15 grams
Radix Arnebiae (Radix Lithospermi) 10-15 gram Rhizoma Atractylodis Macrocephalae 10-20 gram Radix Paeoniae Alba 10-20 grams
Radix Angelicae Sinensis 10-20 gram Fructus Aurantii 10-20 gram grams Radix Ophiopogonis 10-20
The Rhizoma Pinelliae 10-20 gram Radix Astragali 10-20 grams
Wherein, be preferably
Rhizoma Atractylodis 10 gram Cortex Magnoliae Officinalis 10 gram Pericarpium Citri Reticulatae 10 grams
Radix Glycyrrhizae 9 gram Oletum Trogopterori 10 gram Pollen Typhae 10 grams
Radix Ginseng 12 gram Radix Salviae Miltiorrhizae 15 Keshan medicine 15 grams
The Semen Coicis 15 gram Concha Arcae 15 gram Radix Aucklandiae 10 grams
The Radix Arnebiae (Radix Lithospermi) 12 gram Rhizoma Atractylodis Macrocephalae 15 gram Radix Paeoniae Alba 15 grams
Radix Angelicae Sinensis 15 gram Fructus Aurantii 15 gram grams Radix Ophiopogonis 15
The Rhizoma Pinelliae 15 gram Radix Astragali 15 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;
2, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding is dried;
3, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, moistens softly, and shredding is dried or cold drying, sieve dedust bits;
4, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly the time to eighty per cant, run through section, airing;
5, Oletum Trogopterori: choose clean impurity, smash or sieve the dedust bits;
6, Pollen Typhae: rub broken caking, sieve, remove impurity;
7, Radix Ginseng: except removing LU, cutting gets final product;
8, Radix Salviae Miltiorrhizae: choose clean impurity, remove rhizome, clean, pull out, run through rear section, dry;
9, Rhizoma Dioscoreae: choose decontamination, water is captured to steep to the Rhizoma Dioscoreae central part is softening and is pulled out and slightly dry in the air for degree, and section is dried or dried;
10, Semen Coicis: get the Semen Coicis of choosing clean and put in pot and fry to little yellow with slow fire, take out, cool and get final product, or also can (100 jin of every Semen Coiciss are used 10 jin, wheat bran) with stir-fry with wheat bran;
11, Concha Arcae: clean and dry, pulverize;
12, the Radix Aucklandiae: crude drug in whole is put in clear water cleaned, pull out, moistening made soft in 12-24 hours, and section is dried;
13, Radix Arnebiae (Radix Lithospermi): clean, run through, section is dried;
14, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water and pull out after running through, section is dried;
15, the Radix Paeoniae Alba: choose roguing and sanction, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
16, Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening slightly dries in the air when suitable to inside and outside humidity, and section is dried;
17, Fructus Aurantii: remove flesh, core, edulcoration slightly soaks, and pulls out, moistens softly, can pinch doubling as degree take hands, and section is dried;
18, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry;
19, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
20, the Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry.
Two, preparation
1, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Oletum Trogopterori, Pollen Typhae, Radix Ginseng, Radix Salviae Miltiorrhizae, Rhizoma Dioscoreae, Semen Coicis, Concha Arcae, the Radix Aucklandiae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Aurantii, Radix Ophiopogonis, the Rhizoma Pinelliae, the Radix Astragali with described weight decocts with water, add for the first time 2 times of amounts of water, intense fire decocts boiling 30 minutes, use again slow fire boiling 15 minutes, and namely got decoction liquor for the first time.
2, will filter for the first time rear medicinal residues and add 1.5 times of amounts of water, and decoct boiling, more namely got decoction liquor for the second time in 20 minutes with slow fire boiling.
3, twice decoction liquor mixed, then simmered in water 15 minutes, decoction liquor is divided into 2 doses.
Medicine of the present invention has the effect of invigorating the spleen and benefiting QI, stomach function regulating, purging liver-heat, activating blood circulation to dissipate blood stasis, nourishing stomach-YIN, convergence antacid, heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, and treatment gastric ulcer instant effect, short treating period do not recur, and do not rebound.Below further set forth the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get 50 of rabbit, the male and female dual-purpose, body weight 2.5-2.8kg divides two groups, and 25 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is the administration by gavage administration, serve on 20 days every day twice, observes the administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 150 examples for medical treatment, 20-30 years old age, 30 examples, 30-40 years old 50 example, 40-50 years old 40 example, 30 examples more than 50 years old.
2, diagnostic criteria
The gastric ulcer clinical manifestation is epigastrium pain, is positioned under xiphoid-process (pit of the stomach) or around the epigastrium center line, is burning property, nibbling property or hunger property dull pain, distending pain or dull pain.But sometimes also only be confined to the bottom, thoracic cavity.After occuring, pain can continue half an hour to three hour.Disappear when sending out during fitful pain, through after lasting the intermittent pain of several weeks, one period of short duration painless phase can occur.This pain is relevant with diet, often because of hungry, take medicine, acidic food or beverage bring out.Pain can be alleviated because of the base-forming food of taking food, drink water, take.Other may symptoms be heartburn, acid regurgitation water, belch, loss of appetite, lose weight, anemia, vomiting once in a while, will make pain relax after vomiting.
3, Therapeutic Method
Select above-mentioned medicament, take to the patient, each serving with 1 dose, every day early, respectively take 1 evening, and 20 days is a course for the treatment of, takes continuously two courses for the treatment of.
4, efficacy assessment standard
Produce effects: colic symptoms disappears, and gastroscopy ulcer disappears, and physical recovery is normal, observes after half a year without recurrence;
Take a turn for the better: symptom is clearly better, and gastroscopy ulcer is dwindled gradually, and body constitution obviously recovers;
Invalid: symptom does not reach improvement standard person without improvement.
5, therapeutic outcome
Figure 2011102559331100002DEST_PATH_IMAGE001
In above-mentioned treatment, with Drug therapy patients w ith peptic ulcer disease 150 examples of the present invention, produce effects 140 examples as a result, obvious effective rate is 94%, 7 examples that take a turn for the better, improvement rate is 4.67%, invalid 2 examples, total effective rate is 98.67%.

Claims (3)

1. medicine for the treatment of gastric ulcer, it is characterized in that: it is to be made by the crude drug in following weight range:
Rhizoma Atractylodis 5-15 gram Cortex Magnoliae Officinalis 5-15 gram Pericarpium Citri Reticulatae 5-15 grams
Radix Glycyrrhizae 7-11 gram Oletum Trogopterori 5-15 gram Pollen Typhae 5-15 grams
Radix Ginseng 10-15 gram Radix Salviae Miltiorrhizae 10-20 Keshan medicine 10-20 grams
Semen Coicis 10-20 gram Concha Arcae 10-20 gram Radix Aucklandiae 5-15 grams
Radix Arnebiae (Radix Lithospermi) 10-15 gram Rhizoma Atractylodis Macrocephalae 10-20 gram Radix Paeoniae Alba 10-20 grams
Radix Angelicae Sinensis 10-20 gram Fructus Aurantii 10-20 gram grams Radix Ophiopogonis 10-20
The Rhizoma Pinelliae 10-20 gram Radix Astragali 10-20 grams.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Rhizoma Atractylodis 10 gram Cortex Magnoliae Officinalis 10 gram Pericarpium Citri Reticulatae 10 grams
Radix Glycyrrhizae 9 gram Oletum Trogopterori 10 gram Pollen Typhae 10 grams
Radix Ginseng 12 gram Radix Salviae Miltiorrhizae 15 Keshan medicine 15 grams
The Semen Coicis 15 gram Concha Arcae 15 gram Radix Aucklandiae 10 grams
The Radix Arnebiae (Radix Lithospermi) 12 gram Rhizoma Atractylodis Macrocephalae 15 gram Radix Paeoniae Alba 15 grams
Radix Angelicae Sinensis 15 gram Fructus Aurantii 15 gram grams Radix Ophiopogonis 15
The Rhizoma Pinelliae 15 gram Radix Astragali 15 grams.
3. the preparation method of medicinal liquid according to claim 1, it comprises the following steps:
(1) get the raw materials ready
(1) Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;
(2) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding is dried;
(3) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, moistens softly, and shredding is dried or cold drying, sieve dedust bits;
(4) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly the time to eighty per cant, run through section, airing;
(5) Oletum Trogopterori: choose clean impurity, smash or sieve the dedust bits;
(6) Pollen Typhae: rub broken caking, sieve, remove impurity;
(7) Radix Ginseng: except removing LU, cutting;
(8) Radix Salviae Miltiorrhizae: choose clean impurity, remove rhizome, clean, pull out, run through rear section, dry;
(9) Rhizoma Dioscoreae: choose decontamination, water is captured to steep to the Rhizoma Dioscoreae central part is softening and is pulled out and slightly dry in the air for degree, and section is dried or dried;
(10) Semen Coicis: get the Semen Coicis of choosing clean and put in pot and fry to little yellow with slow fire, take out, cool and get final product, or with wheat bran with stir-fry also can, 100 jin of every Semen Coiciss are used 10 jin, wheat bran;
(11) Concha Arcae: clean and dry, pulverize;
(12) Radix Aucklandiae: crude drug in whole is put in clear water cleaned, pull out, moistening made soft in 12-24 hours, and section is dried;
(13) Radix Arnebiae (Radix Lithospermi): clean, run through, section is dried;
(14) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water and pull out after running through, section is dried;
(15) Radix Paeoniae Alba: choose roguing and sanction, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
(16) Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening slightly dries in the air when suitable to inside and outside humidity, and section is dried;
(17) Fructus Aurantii: remove flesh, core, edulcoration slightly soaks, and pulls out, moistens softly, can pinch doubling as degree take hands, and section is dried;
(18) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, take out the heart after running through, then clean and dry;
(19) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
(20) Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
(2) preparation
(1) Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Radix Glycyrrhizae, Oletum Trogopterori, Pollen Typhae, Radix Ginseng, Radix Salviae Miltiorrhizae, Rhizoma Dioscoreae, Semen Coicis, Concha Arcae, the Radix Aucklandiae, Radix Arnebiae (Radix Lithospermi), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Radix Angelicae Sinensis, Fructus Aurantii, Radix Ophiopogonis, the Rhizoma Pinelliae, the Radix Astragali with described weight decocts with water, add for the first time 2 times of amounts of water, intense fire decocts boiling 30 minutes, use again slow fire boiling 15 minutes, and namely got decoction liquor for the first time;
(2) will filter for the first time rear medicinal residues and add 1.5 times of amounts of water, and decoct boiling, more namely got decoction liquor for the second time in 20 minutes with slow fire boiling;
(3) twice decoction liquor mixed, then simmered in water 15 minutes, will boil liquid and be divided into 2 doses.
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