CN102805834B - Drug for curing gastritis and preparation method thereof - Google Patents

Drug for curing gastritis and preparation method thereof Download PDF

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CN102805834B
CN102805834B CN201210294681.8A CN201210294681A CN102805834B CN 102805834 B CN102805834 B CN 102805834B CN 201210294681 A CN201210294681 A CN 201210294681A CN 102805834 B CN102805834 B CN 102805834B
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radix
fructus
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孙凤梅
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Abstract

The invention discloses a drug for curing gastritis and a preparation method thereof. The drug is mainly prepared by adopting radix pseudostellariae, fructus aurantii, radix aucklandiae, liquorice, ladybell roots, radix ophiopogonis, fragrant solomonseal rhizome, dendrobe, szechwan chinaberry fruit, pinellia ternata, dandelion, cassia seeds, edestan, officinal magnolia bark and semen coicis according to a certain weight ratio. The drug disclosed by the invention achieves the effects of warming the middle warmer, nourishing spleen, reconciling the spleen and kidney, tretching liver to smooth Qi, harmonizing stomach and alleviating pain, is used for curing the gastritis and has the advantages of short treatment course, quick effectiveness, no toxicity and no side effect.

Description

A kind of medicine for the treatment of gastritis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of gastritis and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Gastritis is the general designation of stomach lining inflammation.Commonly encountered diseases, can be divided into acute and chronic two classes.Acute gastritis is common is two kinds of pure and erosives.The former shows as epigastric discomfort, pain, anorexia and feels sick, vomits; The latter's digestive tract hemorrhage is main manifestations, has hematemesis and melena.Chronic gastritis can be divided into superficial gastritis, atrophic gastritis and hypertrophic gastritis again conventionally.Chronic gastritis course of disease delay, non-evident sympton and sign mostly, the indigestion symptoms such as general rarely seen glutted, pantothenic acid after meal, belch, irregularities stomachache.Make a definite diagnosis main dependence gastroscopy stomach function regulating biopsy of mucous membrane.Primary disease is common in adult, and many causes of disease can stimulate stomach, and as improper diet, virus and antibacterial infection, medicine irritation etc. all may cause primary disease.At present, due to western medicine gastritis poor effect, and long-term taking Western medicine has a lot of side effect, and therefore, people exist very large demand to the Chinese medicine of effective treatment gastritis.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the Chinese medicine of effective treatment gastritis, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition that can effectively treat gastritis.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention is to select Radix Pseudostellariae, Fructus Evodiae, Fructus Aurantii, the Radix Aucklandiae, Bulbus Allii Macrostemonis, Rhizoma Cyperi, Massa Medicata Fermentata, Radix Glycyrrhizae, Radix Adenophorae, Radix Ophiopogonis, Rhizoma Polygonati Odorati, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Herba Dendrobii, Fructus Toosendan, the Rhizoma Pinelliae, Herba Taraxaci, Fructus Chaenomelis, Fructus Crataegi, Semen Cassiae, Fructus Cannabis, Semen Armeniacae Amarum, Talcum, Medulla Tetrapanacis, Fructus Amomi Rotundus, Folium Bambusae, Cortex Magnoliae Officinalis, Semen Coicis, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat gastritis.Wherein selecting Radix Pseudostellariae is that tepor, enters the heart, spleen, lung three warps, has the function of tonifying the lung, spleen invigorating, controls cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Fructus Evodiae to be because its nature and flavor are pungent, temperature, poisonous, enter liver, stomach warp, there is warming middle-JIAO, pain relieving, regulates the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Select Fructus Aurantii to be because its nature and flavor toil, cool.Enter lung, spleen, large intestine channel.Dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select the Radix Aucklandiae to be because its nature and flavor are arduous, temperature, enters lung, liver, spleen channel, has promoting the circulation of QI to relieve pain, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and vomiting, has loose bowels, dysentery tenesmus, colic of cold type.Select Bulbus Allii Macrostemonis to be because its nature and flavor are arduous, temperature, enters meridian of Hand-YANG MING, regulates the flow of vital energy, and the chest stuffiness relieving, activates yang, and the function of eliminating stagnation is controlled the thorough back of the body of obstruction of qi in the chest and cardialgia, and gastral cavity painful abdominal mass is not relaxed, and retches, heavy after dysentery, furuncle.Select Rhizoma Cyperi to be because the pungent micro-hard work of its nature and flavor is flat, enter liver, tri-jiao channel, the resolving depression of regulating the flow of vital energy, the function of pain relieving regulating menstruation, treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.Select Massa Medicata Fermentata to be because its nature and flavor sweet, acrid, warm enters upright stone tablet, stomach warp, have invigorating the spleen and regulating the stomach, the function helping digestion in adjusting, controls retention of food and drink, feeling of stuffiness in chest abdominal distention, and vomiting dysentery, postnatal blood stasis stomachache, children's's enlarged abdomen is hard long-pending.Select Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, there are and middle emergency lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription; Process use, control taste lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus , Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, and carbuncle subcutaneous ulcer skin infection, separates poison of drug and alimentary toxicosis.Select Radix Adenophorae to be because its nature and flavor are sweet, be slightly cold, attach to the lung and stomach meridians, have nourishing YIN and clearing away lung-heat, reduce phlegm, the function of QI invigorating, controls lung-heat type cough, deficiency of YIN phthisical cough, and dry cough expectorant is glutinous, deficiency of both vital energy and Yin, restlessness and fever with thirst.Select be Radix Ophiopogonis because its property sweet and slightly bitter taste is cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid, controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, thirsty clearly, calentura Tianjin wound, dry mouth and throat, constipation.Select Rhizoma Polygonati Odorati to be because its nature and flavor are sweet, flat, enter lung, stomach warp, has yin nourishing, moisturizes, relieving restlessness, the function of quenching the thirst, controls calentura sun wound, cough, excessive thirst, deficient fever, rapid digestion of food is easily hungry, frequent micturition.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid, controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, sends out speckle dermexanthesis.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Radix Glycyrrhizae to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, processs use, controls weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus , Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, and ulcer sores, separates poison of drug and alimentary toxicosis.Select Herba Dendrobii to be because its property slightly sweet flavor is micro-salty, cold, enter to have, lung, kidney channel, there is the stomach reinforcing of promoting the production of body fluid, the function of clearing away heat and nourishing YIN, controls consumption of body fluid caused by febrile disease, and xerostomia is tired drinks, deficiency-heat after being ill, it is dark that the moon is hindered order.Select Fructus Toosendan to be because its nature and flavor are bitter, cold, poisonous, enter liver, stomach, small intestine meridian, there is wet down heat, clearing away liver-fire, pain relieving, the function of parasite killing, controls epigastric pain with cold limbs due to adverseness of heat, hypochondriac pain, colic, abdominal pain due to worm stagnation.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, there is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, controls damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select Herba Taraxaci to be because its property bitter but sweet flavor is cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Fructus Chaenomelis to be because its nature and flavor are sour, temperature, enters liver, spleen channel, has suppressing the hyperactive liver and easing the stomach, and the function of the relaxing muscles and tendons that dries being controlled the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.Select Fructus Crataegi to be because its nature and flavor acid is sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji , mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's's breast food is stagnated.Select Semen Cassiae to be because its property bitter but sweet flavor is cool, enter liver, kidney channel, have liver heat removing, improving eyesight, diuretic, the function of relieving constipation, controls wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, liver cirrhosis abdomen, habitual constipation.Select Fructus Cannabis to be because its nature and flavor are sweet, flat, enter spleen, stomach, large intestine channel, have and moisturize, laxation, treating stranguria, the function of invigorating blood circulation, controls dryness of the intestine constipation, quench one's thirst, pyretic stranguria, migratory arthralgia, dysentery, menoxenia, scabies, tinea is insane.Select Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, enter lung, large intestine channel, there is expelling phlegm for arresting cough, to relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Select Pulvis Talci to be because its nature and flavor are sweet, light, cold, return bladder, lung, stomach warp, have inducing diuresis for treating stranguria syndrome, heat-clearing and toxic substances removing, the function of damp eliminating expelling summer-heat, controls hematodiarrhoea, and gonorrhea is urinated hot puckery pain, heat-damp in summer excessive thirst, damp and hot watery diarrhea, external treatment eczema, eczema, miliaria.Select Medulla Tetrapanacis to be because its property slightly sweet flavor is cool, enter lung, stomach warp, have eliminating the pathogens from the lung, diuresis, the function of lower milk, controls dysuria, gonorrhea, edema, puerpera's galactostasis, blurred vision, nasal obstruction.Select Fructus Amomi Rotundus be because its nature and flavor pungent, temperature, enters lung, spleen channel, has sector-style, warming the stomach, helps digestion, the function of alleviating distention in middle-JIAO, controls the stagnation of QI, dyspepsia is uncomfortable in chest, abdominal distention, eructation, dysphagic, tell contrary, regurgitation, malaria.Select Herba Lophatheri to be because its property slightly sweet flavor is cold, enter heart kidney two warps, have clearing away heart-fire, heat clearing away and restlessness relieving, the function of diuresis, controls calentura thirsty, vexed, hot urination, stranguria with turbid discharge, erosion of the oral mucosa tongue boil, gingival swelling and pain.Selecting Cortex Magnoliae Officinalis is that temperature, enters spleen, stomach, large intestine channel, has warming middle-JIAO because of its nature and flavor toil, the therapeutic method to keep the adverse QI flowing downwards, and dampness, the function of expectorant, controls breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Semen Coicis to be because its property slightly sweet flavor is cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and has loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
6-10 grams of 6-10 grams of Fructus Aurantiis of 8-12 grams of Fructus Evodiaes of Radix Pseudostellariae
5-15 grams of 15-25 grams of Rhizoma Cyperis of 6-10 grams of Bulbus Allii Macrostemonis of the Radix Aucklandiae
15-25 grams of 6-10 grams of Radix Adenophoraes of 5-15 grams of Radix Glycyrrhizaes of Massa Medicata Fermentata
5-15 grams of 5-15 grams of Radix Rehmanniae of 15-25 grams of Rhizoma Polygonati Odorati Radix Ophiopogonis
15-25 grams of 6-10 grams of Herba Dendrobiis of 5-15 grams of Radix Glycyrrhizaes of the Radix Paeoniae Alba
6-10 grams of 15-25 grams of Herba Taraxacis of 6-10 grams of Rhizoma Pinelliaes of Fructus Toosendan
5-15 grams of 5-15 grams of Semen Cassiaes of Fructus Chaenomelis 15-25 Keshan short, bristly hair or beards
6-10 grams, 6-10 grams of Talcums of 6-10 grams of Semen Armeniacae Amarums of Fructus Cannabis
5-15 grams, 5-15 grams of Folium Bambusaes of 5-15 grams of Fructus Amomi Rotunduss of Medulla Tetrapanacis
15-25 grams of 15-25 grams of Semen Coiciss of Cortex Magnoliae Officinalis
Preferable amount is
8 grams of 8 grams of Fructus Aurantiis of 10 grams of Fructus Evodiaes of Radix Pseudostellariae
10 grams of 20 grams of Rhizoma Cyperis of 8 grams of Bulbus Allii Macrostemonis of the Radix Aucklandiae
20 grams of 8 grams of Radix Adenophoraes of 10 grams of Radix Glycyrrhizaes of Massa Medicata Fermentata
10 grams of 10 grams of Radix Rehmanniae of 20 grams of Rhizoma Polygonati Odorati Radix Ophiopogonis
20 grams of 8 grams of Herba Dendrobiis of 10 grams of Radix Glycyrrhizaes of the Radix Paeoniae Alba
8 grams of 20 grams of Herba Taraxacis of 8 grams of Rhizoma Pinelliaes of Fructus Toosendan
10 grams of 10 grams of Semen Cassiaes of Fructus Chaenomelis 20 Keshan short, bristly hair or beard
8 grams, 8 grams of Talcums of 8 grams of Semen Armeniacae Amarums of Fructus Cannabis
10 grams, 10 grams of Folium Bambusaes of 10 grams of Fructus Amomi Rotunduss of Medulla Tetrapanacis
20 grams of 20 grams of Semen Coiciss of Cortex Magnoliae Officinalis
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Pseudostellariae: extract fibrous root, dry;
2, Fructus Evodiae: choose decontamination, dry;
3, Fructus Aurantii: remove flesh, core, clean, slightly soak, pull out, soften, the hands of take can be pinched doubling as degree, and section, dries;
4, the Radix Aucklandiae: crude drug in whole is put in clear water and cleaned, pull out, moistening makes soft for 12-24 hours, section, dries;
5, Bulbus Allii Macrostemonis: choose decontamination, the sieve of winnowing with a dustpan goes whisker;
6, Rhizoma Cyperi: choose decontamination, be ground into particle, winnow with a dustpan fine, soft fur and smalls;
7, Massa Medicata Fermentata: get wheat bran and sprinkle evenly in heat pot, the cigarette of having waited, pours Massa Medicata Fermentata into, fries to yellow, takes out, and sieve removes wheat bran, cools;
8, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
9, Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, dry;
10, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;
11, Rhizoma Polygonati Odorati: remove impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;
12, Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
13, the Radix Paeoniae Alba: choose roguing and sanction, size separately, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
14, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
15, Herba Dendrobii: get dry Herba Dendrobii, saturating with approximately to eighty per cant of blister, stewing profit, removes undesirable root and black branch, and cutting, hits thin film, dries;
16, Fructus Toosendan: choose decontamination, clean, dry grating or cleave in two;
17, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
18, Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
19, Fructus Chaenomelis: clear water is cleaned, slightly soaks, and moistening, to thoroughly, is put in food steamer and cooked, and takes advantage of fervent sheet, and weather exposure, take by the red atropurpureus that turns as degree;
20, Fructus Crataegi: choose clean impurity, sieve enucleation;
21, Semen Cassiae: get clean Semen Cassiae, put in pot and fry extremely micro-fragrance that has, take out, cool;
22, Fructus Cannabis: choose decontamination and residual shell, get clean core;
23, Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, winnows with a dustpan clean;
24, Talcum: get clean Talcum, break into fragment, water flies or be ground into superfine powder;
25, Medulla Tetrapanacis: choose decontamination, section;
26, Fructus Amomi Rotundus: choose clean impurity, sieve scurf removing, smashes, or peel off shell, gets core and smashes use;
27, Folium Bambusae: choose clean impurity, dry;
28, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding, dries;
29, Semen Coicis: get crude drug, remove residual cot, impurity.
Two, preparation
1, the Radix Pseudostellariae of described weight, Fructus Evodiae, Fructus Aurantii, the Radix Aucklandiae, Bulbus Allii Macrostemonis, Rhizoma Cyperi, Massa Medicata Fermentata, Radix Glycyrrhizae, Radix Adenophorae, Radix Ophiopogonis, Rhizoma Polygonati Odorati, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Herba Dendrobii, Fructus Toosendan, the Rhizoma Pinelliae, Herba Taraxaci, Fructus Chaenomelis, Fructus Crataegi, Semen Cassiae, Fructus Cannabis, Semen Armeniacae Amarum, Talcum, Medulla Tetrapanacis, Fructus Amomi Rotundus, Folium Bambusae, Cortex Magnoliae Officinalis, Semen Coicis medicine are decocted with water, add for the first time 4 times of amounts of water, soak after 100 minutes, intense fire decocts boiling, with slow fire boiling, within 20 minutes, obtain decoction liquor for the first time again, decoction liquor is poured in container for the first time.
2, the medicinal residues after filtering are for the first time added to 3 times of amounts that water is former medicine, first boil with high heat, then use slow fire boiling 20 minutes, decoction liquor is poured in container for the second time.
3, the medicinal residues after filtering are for the second time added to 1 times of amount that water is former medicine, first boil with high heat, then use slow fire boiling 10 minutes, decoction liquor is poured in container for the third time.
Three decoction liquor are carried out to mixing and stirring, then use slow fire boiling 20 minutes, be divided into 9 doses and take.
Medicine of the present invention has warming middle-JIAO spleen reinforcing, the spleen and stomach regulating, and depressed liver-energy dispersing and QI regulating, and the effect of stomach and alleviating pain, be used for the treatment of gastritis, and short treating period, instant effect, have no side effect.
The specific embodiment:
By test example, further set forth below the beneficial effect of medicine of the present invention, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get 40 of rabbit, male and female dual-purpose, body weight 2.0-2.3kg, divides two groups, and 20 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 10 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] Drug therapy gastritis of the present invention:
1, physical data
Accept out-patient's totally 300 examples for medical treatment, acute patient's 120 examples wherein, Patients with Chronic Gastritis 180 examples.
2, diagnostic criteria
Acute gastritis refers to a kind of acute inflammatory reaction of the gastric mucosa that a variety of causes causes.Acute gastritis patient often has Upper abdominal pain, feels sick, belch, vomiting and loss of appetite etc.Not etc., but disease is all not hurried, mostly has obvious paathogenic factor for the normal weight of its clinical manifestation, as eating and drinking too much at one meal, heavy drinking or eat unclean food by mistake, suffer from cold, drug administration etc.The gastritis being caused by medicine and stressors, often only shows as hematemesis and melena, is generally on a small quantity, is intermittent, can certainly stop, but also massive hemorrhage can occur.Separately have on some patient clinicals asymptomaticly, only at stomach Microscopic observation, have the stomach lining inflammation of acute gastritis to change.
Chronic gastritis is to take the chronic gastropathy that the non-specific chronic inflammatory disease of gastric mucosa is main pathological change, and pathological changes can be confined to a part for stomach, and whole stomach also can permeate.Clinical manifestation lacks specificity, and the lesion degree of symptom weight and gastric mucosa is also non-uniform.Most patient is normal asymptomatic or have an indigestion symptom that degree is different, as epigastric discomfort and pain, nausea and vomiting, loss of appetite, glutted, acid regurgitation belch etc. after the meal.Gastric mucosal erosive haemorrhage person accompanies hematemesis, melena.Patients with atrophic gastritis can have gastric acid minimizing, dyspepsia, anemia, becomes thin, glossitis, diarrhoea etc., and indivedual patients accompany mucosal erosion person's upper abdominal pain more obvious, and can have hemorrhage.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, acute patient is each serving with 1 dose, and every day early, respectively take 1 evening, within 15 days, is a course for the treatment of, takes 2 courses for the treatment of.Chronic patients is each serving with 1 dose, and every day, early, middle and late respectively clothes 1 time, 15 days was a course for the treatment of, took continuously 4 courses for the treatment of.
4, efficacy assessment standard
Effective: clinical symptom disappearance after treatment, it is normal that body constitution is recovered, and observes half a year without recidivist;
Take a turn for the better: clinical symptoms is obviously improved, and body constitution is progressively recovered;
Invalid: clinical partial symptoms disappears or without change, do not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
Figure 437400DEST_PATH_IMAGE001
In above-mentioned treatment, by Drug therapy gastritis sufferer's 300 examples of the present invention, acute patient's 120 examples wherein, effective 114 examples of result, obvious effective rate is 95%, 5 examples that take a turn for the better, improvement rate is 4.17%, invalid 1 example, total effective rate is 99.17%.Heavy class patient 180 examples, effective 172 examples of result, obvious effective rate is 95.56%, 6 examples that take a turn for the better, improvement rate is 3.33%, invalid 2 examples, total effective rate is 98.89%.

Claims (3)

1. a medicine for the treatment of gastritis, is characterized in that: it is to be made by the crude drug within the scope of following weight:
6-10 grams of 6-10 grams of Fructus Aurantiis of 8-12 grams of Fructus Evodiaes of Radix Pseudostellariae
5-15 grams of 15-25 grams of Rhizoma Cyperis of 6-10 grams of Bulbus Allii Macrostemonis of the Radix Aucklandiae
15-25 grams of 6-10 grams of Radix Adenophoraes of 5-15 grams of Radix Glycyrrhizaes of Massa Medicata Fermentata
5-15 grams of 5-15 grams of Radix Rehmanniae of 15-25 grams of Rhizoma Polygonati Odorati Radix Ophiopogonis
15-25 grams of 6-10 grams of Herba Dendrobiis of 5-15 grams of Radix Glycyrrhizaes of the Radix Paeoniae Alba
6-10 grams of 15-25 grams of Herba Taraxacis of 6-10 grams of Rhizoma Pinelliaes of Fructus Toosendan
5-15 grams of 5-15 grams of Semen Cassiaes of Fructus Chaenomelis 15-25 Keshan short, bristly hair or beards
6-10 grams, 6-10 grams of Talcums of 6-10 grams of Semen Armeniacae Amarums of Fructus Cannabis
5-15 grams, 5-15 grams of Folium Bambusaes of 5-15 grams of Fructus Amomi Rotunduss of Medulla Tetrapanacis
15-25 grams of 15-25 grams of Semen Coiciss of Cortex Magnoliae Officinalis.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
8 grams of 8 grams of Fructus Aurantiis of 10 grams of Fructus Evodiaes of Radix Pseudostellariae
10 grams of 20 grams of Rhizoma Cyperis of 8 grams of Bulbus Allii Macrostemonis of the Radix Aucklandiae
20 grams of 8 grams of Radix Adenophoraes of 10 grams of Radix Glycyrrhizaes of Massa Medicata Fermentata
10 grams of 10 grams of Radix Rehmanniae of 20 grams of Rhizoma Polygonati Odorati Radix Ophiopogonis
20 grams of 8 grams of Herba Dendrobiis of 10 grams of Radix Glycyrrhizaes of the Radix Paeoniae Alba
8 grams of 20 grams of Herba Taraxacis of 8 grams of Rhizoma Pinelliaes of Fructus Toosendan
10 grams of 10 grams of Semen Cassiaes of Fructus Chaenomelis 20 Keshan short, bristly hair or beard
8 grams, 8 grams of Talcums of 8 grams of Semen Armeniacae Amarums of Fructus Cannabis
10 grams, 10 grams of Folium Bambusaes of 10 grams of Fructus Amomi Rotunduss of Medulla Tetrapanacis
20 grams of 20 grams of Semen Coiciss of Cortex Magnoliae Officinalis.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Radix Pseudostellariae: extract fibrous root, dry;
(2) Fructus Evodiae: choose decontamination, dry;
(3) Fructus Aurantii: remove flesh, core, clean, slightly soak, pull out, soften, the hands of take can be pinched doubling as degree, and section, dries;
(4) Radix Aucklandiae: crude drug in whole is put in clear water and cleaned, pull out, stewing profit makes soft for 12-24 hours, and section, dries;
(5) Bulbus Allii Macrostemonis: choose decontamination, the sieve of winnowing with a dustpan goes whisker;
(6) Rhizoma Cyperi: choose decontamination, be ground into particle, winnow with a dustpan fine, soft fur and smalls;
(7) Massa Medicata Fermentata: get wheat bran and sprinkle evenly in heat pot, the cigarette of having waited, pours Massa Medicata Fermentata into, fries to yellow, takes out, and sieve removes wheat bran, cools;
(8) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
(9) Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, dry;
(10) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;
(11) Rhizoma Polygonati Odorati: remove impurity, clean earth, stewing profit is even to inside and outside humidity, and section, dries;
(12) Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
(13) Radix Paeoniae Alba: choose decontamination, size separately, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(14) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water and, pull out thoroughly time to eighty per cant, run through section, dry;
(15) Herba Dendrobii: get dry Herba Dendrobii, saturating with approximately to eighty per cant of blister, stewing profit, removes undesirable root and black branch, and cutting, hits thin film, dries;
(16) Fructus Toosendan: choose decontamination, clean, dry grating or cleave in two;
(17) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
(18) Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
(19) Fructus Chaenomelis: clear water is cleaned, slightly soaks, and stewing profit, to thoroughly, is put in food steamer and cooked, section while hot, and weather exposure, take by the red atropurpureus that turns as degree;
(20) Fructus Crataegi: choose clean impurity, sieve enucleation;
(21) Semen Cassiae: get clean Semen Cassiae, put in pot and fry extremely micro-fragrance that has, take out, cool;
(22) Fructus Cannabis: choose decontamination and residual shell, get clean core;
(23) Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, the Pi Wei that waits purses up and pulls out, soaks in cold water, sloughs kind of a skin, dries, winnows with a dustpan clean;
(24) Talcum: get clean Talcum, break into fragment, water flies or be ground into superfine powder;
(25) Medulla Tetrapanacis: choose decontamination, section;
(26) Fructus Amomi Rotundus: choose clean impurity, sieve scurf removing, smashes, or peel off shell, gets core and smashes use;
(27) Folium Bambusae: choose clean impurity, dry;
(28) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding, dries;
(29) Semen Coicis: get crude drug, remove residual cot, impurity;
(2) preparation
(1) Radix Pseudostellariae of described weight, Fructus Evodiae, Fructus Aurantii, the Radix Aucklandiae, Bulbus Allii Macrostemonis, Rhizoma Cyperi, Massa Medicata Fermentata, Radix Glycyrrhizae, Radix Adenophorae, Radix Ophiopogonis, Rhizoma Polygonati Odorati, Radix Rehmanniae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Herba Dendrobii, Fructus Toosendan, the Rhizoma Pinelliae, Herba Taraxaci, Fructus Chaenomelis, Fructus Crataegi, Semen Cassiae, Fructus Cannabis, Semen Armeniacae Amarum, Talcum, Medulla Tetrapanacis, Fructus Amomi Rotundus, Folium Bambusae, Cortex Magnoliae Officinalis, Semen Coicis medicine are decocted with water, add for the first time 4 times of amounts of water, soak after 100 minutes, intense fire decocts boiling, with slow fire boiling, within 20 minutes, obtain decoction liquor for the first time again, decoction liquor is poured in container for the first time;
(2) medicinal residues after filtering are for the first time added to 3 times of amounts that water is former medicine, first boil with high heat, then use slow fire boiling 20 minutes, decoction liquor is poured in container for the second time;
(3) medicinal residues after filtering are for the second time added to 1 times of amount that water is former medicine, first boil with high heat, then use slow fire boiling 10 minutes, decoction liquor is poured in container for the third time;
Three decoction liquor are carried out to mixing and stirring, then use slow fire boiling 20 minutes, be divided into 9 doses and take.
CN201210294681.8A 2012-08-20 2012-08-20 Drug for curing gastritis and preparation method thereof Expired - Fee Related CN102805834B (en)

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CN104352920A (en) * 2014-10-24 2015-02-18 万鹏波 Digestion-helping and stomach-conditioning traditional Chinese medicinal composition

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