CN102805825B - Drug for curing cutaneous pruritus and preparation method thereof - Google Patents

Drug for curing cutaneous pruritus and preparation method thereof Download PDF

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CN102805825B
CN102805825B CN2012103074559A CN201210307455A CN102805825B CN 102805825 B CN102805825 B CN 102805825B CN 2012103074559 A CN2012103074559 A CN 2012103074559A CN 201210307455 A CN201210307455 A CN 201210307455A CN 102805825 B CN102805825 B CN 102805825B
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radix
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兰恒志
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Abstract

The invention discloses a drug for curing cutaneous pruritus and a preparation method thereof. The drug is mainly prepared by adopting polygonum multiflorum, flower of Chinese scholartree, manyleaf paris rhizome, fried fructus aurantii, salvia miltiorrhiza, prepared rehmannia roots, zaocys dhumnade, gentiana macrophylla and black sesame according to a certain weight ratio. The drug performs the functions of promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, diminishing inflammation and relieving itching, is used for curing the cutaneous pruritus and has the advantages of quick effectiveness, short treatment course, no relapse and high cure rate.

Description

A kind of medicine for the treatment of skin pruritus and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of skin pruritus and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Skin pruritus refers to without former breakout, but a kind of dermatosis of pruritus is arranged, and the traditional Chinese medical science is referred to as pruritus caused by wind pathogen.Skin pruritus belongs to the neuropsychiatric dermatosis, is a kind of skin neurosis illness.To only have skin pruritus clinically and be referred to as pruritus without the primary cutaneous impairer.The category that belongs to the traditional Chinese medical science " pruritus ".At present, western medicine skin pruritus poor effect, and more side effect is arranged, therefore, there is great demand in people to the Chinese medicine of effective treatment skin pruritus.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment skin pruritus, thereby has completed the present invention.
Purpose of the present invention just is to provide a kind of composition of medicine that can treat skin pruritus.
Another object of the present invention just has been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects Radix Polygoni Multiflori, Flos Sophorae, Rhizoma Paridis, Fructus Aurantii (parched), Pericarpium Citri Reticulatae, Rhizoma Imperatae, Semen Ziziphi Spinosae (parched), Periostracum Cicadae, Cortex Cinnamomi, Radix Ophiopogonis, Fructus Mori, Radix Gentianae, Fructus Ligustri Lucidi, Radix Angelicae Sinensis, Poria cum Radix Pini, Radix Salviae Miltiorrhizae, Radix Rehmanniae Preparata, Zaocys, Radix Gentianae Macrophyllae and Semen Sesami Nigrum to be combined, by these drug regimens, make each efficacy of drugs produce synergism, thereby can effectively treat the recurrence of skin pruritus.Wherein select Radix Polygoni Multiflori to be because its nature and flavor are bitter, sweet, puckery, warm, return liver, the heart, kidney channel, invigorating the liver and kidney is arranged, benefiting essence-blood, black beard and hair, the function of bone and muscle strengthening, control blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void.Select Flos Sophorae to be because its nature and flavor hardship is cool, enter liver, large intestine channel, heat clearing away is arranged, removing heat from blood, the function of hemostasis, control discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis, under dysentery with red and white feces, the wind heat conjunctival congestion, skin sore, and for prevention of stroke.Select Rhizoma Paridis to be because its nature and flavor toil is cold, poisonous, enter the heart, Liver Channel, heat-clearing and toxic substances removing is arranged, antiasthmatic-antitussive, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., control carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, infantile convulsion is twitched, snake bite and insect sting.Selecting Fructus Aurantii is because its nature and flavor toil, cool, enters lung, spleen, large intestine channel, and dispelling the stagnated QI is arranged, row expectorant, the function of removing food stagnancy, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Pericarpium Citri Reticulatae to be because its nature and flavor are bitter, hot, temperature, return lung, spleen channel, and regulating qi-flowing for strengthening spleen is arranged, and the function of drying dampness to eliminate phlegm, control fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae, enters lung, stomach, small intestine meridian, and removing heat from blood is arranged, hemostasis, and heat clearing away, the function of diuresis, control the calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select Semen Ziziphi Spinosae to be because its nature and flavor are sweet, flat, enter the heart, spleen, liver, gallbladder meridian, nourishing the liver is arranged, mind calming, calm the nerves, and the function of arresting sweating, control restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.Selecting Periostracum Cicadae is because its property sweet-salty, cool, enters lung, Liver Channel, and loose wind heat is arranged, and lung qi dispersing determine the function of convulsion, controls affection due to external wind and heat, the cough hoarseness, and measles is thoroughly not smooth, the rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Selecting Cortex Cinnamomi is that heat, enter kidney, spleen, urinary bladder channel, and the complement sun is arranged, warming the spleen and stomach, removing accumulated cold because of its property acrid-sweet flavor, the function of promoting blood circulation, control decline of the fire from the gate of life, the cold extremities faint pulse, and the YANG-depletion collapse, stomachache is had loose bowels, the colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Select be Radix Ophiopogonis because its property sweet and slightly bitter taste is cold, enter lung, stomach, heart channel, nourishing YIN and moistening the lung is arranged, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid, control dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, the asthenia dysphoria with smothery sensation, clear thirsty, calentura Tianjin wound, dry mouth and throat, constipation.Select Fructus Mori to be because its nature and flavor are sweet, cold, enter liver, kidney channel, have tonifying liver, and kidney tonifying relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows the function of liquid, controls hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Select Radix Gentianae to be because its nature and flavor hardship is cold, enter liver, gallbladder meridian, the eliminating pathogen in the liver excess-fire is arranged, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat , Jing Epilepsy, encephalitis B, and headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the carbuncle skin infection, scrotum swells and ache, the pudendum pruritus due to damp pathogen.Select Fructus Ligustri Lucidi to be because its property bitter but sweet flavor is flat, enter liver, kidney channel, invigorating the liver and kidney is arranged, the function of strong waist knee joint, control yin asthenia generating intrinsic heat, dizziness, order flower tinnitus, soreness of the waist and knees, early whitening of beard and hair.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm enters the heart, liver, spleen channel, benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, the dryness of the intestine difficulty just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Poria cum Radix Pini to be because its property slightly sweet flavor is flat, enter the heart, spleen channel, mind calming is arranged, calm the nerves, the function of diuretic, control the palpitation with fear of having a guilty conscience, forgetful, insomnia, frightened Epilepsy, dysuria.Selecting Radix Salviae Miltiorrhizae is that tepor, enter the heart, Liver Channel, and blood circulation and promoting silt is arranged because of its nature and flavor hardship, calming heart and tranquilizing mind, and evacuation of pus, the function of pain relieving, control angina cordis, menoxenia, dysmenorrhea, to close, metrorrhagia leukorrhagia , mass in the abdomen, gather, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Radix Rehmanniae Preparata to be because its nature and flavor are sweet, tepor, enter liver, kidney channel, and YIN nourishing is arranged, and the function of enriching blood is controlled deficiency of YIN insufficiency of blood, the waist knee flaccidity, and the chronic cough hectic fever due to YIN-deficiency, seminal emission, metrorrhagia, menoxenia, quench one's thirst, frequency of micturition, deafness, blurred vision.Select Zaocys to be because its nature and flavor are sweet, flat, return Liver Channel, dispelling, collateral-activating is arranged, spasmolytic, dispelling the wind and dampness pathogens arthralgia pain, numb limbs and tense tendons, tic spasm, skin pruritus, leprosy.Select Radix Gentianae Macrophyllae to be because its nature and flavor toil is flat, enter liver, stomach, gallbladder meridian, expelling wind and removing dampness is arranged, and the blood relaxing muscles and tendons, the function of clearing away heat and promoting diuresis, the dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture, jaundice, have blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Select Semen Sesami Nigrum, the different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, and invigorating the liver and kidney is arranged, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.
The specific embodiment
The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope
Radix Polygoni Multiflori 15-25 gram Flos Sophorae 10-20 gram Rhizoma Paridis 10-20 gram
Fructus Aurantii (parched) 15-25 gram Pericarpium Citri Reticulatae 10-20 gram Rhizoma Imperatae 10-20 gram
Semen Ziziphi Spinosae (parched) 20-30 gram Periostracum Cicadae 8-12 gram Cortex Cinnamomi 10-20 gram
Radix Ophiopogonis 10-20 gram Fructus Mori 8-12 cron Radix Gentianae 15-25 gram
Fructus Ligustri Lucidi 10-20 gram Radix Angelicae Sinensis 10-20 gram Poria cum Radix Pini 20-30 gram
Radix Salviae Miltiorrhizae 8-12 gram Radix Rehmanniae Preparata 10-20 gram Zaocys 10-20 gram
Radix Gentianae Macrophyllae 8-12 gram Semen Sesami Nigrum 10-20 gram
Wherein, be preferably
Radix Polygoni Multiflori 20 gram Flos Sophorae 15 gram Rhizoma Paridis 15 grams
Fructus Aurantii (parched) 15 gram Pericarpium Citri Reticulatae 15 gram Rhizoma Imperatae 15 grams
Semen Ziziphi Spinosae (parched) 25 gram Periostracum Cicadae 10 gram Cortex Cinnamomi 15 grams
Radix Ophiopogonis 15 gram Fructus Mori 10 cron Radix Gentianae 20 grams
Fructus Ligustri Lucidi 15 gram Radix Angelicae Sinensis 12 gram Poria cum Radix Pini 25 grams
Radix Salviae Miltiorrhizae 10 gram Radix Rehmanniae Preparata 15 gram Zaocys 10 grams
Radix Gentianae Macrophyllae 10 gram Semen Sesami Nigrum 15 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Polygoni Multiflori: choose decontamination, clean, saturating with blister to eighty per cant, to pull out, profit is even to inside and outside humidity, and section or dice, dry;
2, Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
3, Rhizoma Paridis: get crude drug, remove impurity, slightly soak, clean, run through, cut sheet, drying, sieve removes chip;
4, Fructus Aurantii (parched): get wheat bran and be spread in the heat pot, when the yellow skin of waiting is smoldered, add the Fructus Aurantii sheet, fry to faint yellow, take out, sieve removes wheat bran, cools, and 100 jin of every Fructus Aurantii sheets, with 10 jin, wheat bran;
5, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dry or cold drying, sieve dedust bits;
6, Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dry, the clean chip of winnowing with a dustpan;
7, Semen Ziziphi Spinosae (parched): get clean Semen Ziziphi Spinosae, put in pot and fry to crust and heave and be micro-yellow with slow fire, take out, cool;
8, Periostracum Cicadae: choose decontamination, clean and dry;
9, Cortex Cinnamomi: choose clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, by warm water, infiltrates a moment, and section, dry;
10, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, after running through, pump the heart, then clean and dry;
11, Fructus Mori: wash, choose decontamination, extract long handle, dry;
12, Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
13, Fructus Ligustri Lucidi: choose decontamination, clean, dry;
14, Radix Angelicae Sinensis: choose roguing and sanction, clean, moistening, slightly dry in the air when suitable to inside and outside humidity, and section is dried;
15, Poria cum Radix Pini: get crude drug, remove impurity, section, dry in the shade;
16, Herba Portulacae: choose clean impurity, remove undesirable root, slightly moisten with water, cutting is dried;
17, Radix Salviae Miltiorrhizae: choose clean impurity, remove rhizome, clean, pull out, run through rear section, dry;
18, Radix Rehmanniae Preparata: select clean Radix Rehmanniae Preparata to get final product;
19, Zaocys: get crude drug, brush away ash bits, the used time decaptitates, squama, cutting;
20, Radix Gentianae Macrophyllae: choose decontamination, except removing LU, slightly soak, run through section, dry;
21, Semen Sesami Nigrum: get crude drug, remove impurity, sieve removes chip.
Two, preparation
Add 1500 ml waters to soak 60 minutes the Radix Polygoni Multiflori of described weight, Flos Sophorae, Rhizoma Paridis, Fructus Aurantii (parched), Pericarpium Citri Reticulatae, Rhizoma Imperatae, Semen Ziziphi Spinosae (parched), Periostracum Cicadae, Cortex Cinnamomi, Radix Ophiopogonis, Fructus Mori, Radix Gentianae, Fructus Ligustri Lucidi, Radix Angelicae Sinensis, Poria cum Radix Pini, Radix Salviae Miltiorrhizae, Radix Rehmanniae Preparata, Zaocys, Radix Gentianae Macrophyllae, Semen Sesami Nigrum, intense fire decocts boiling 30 minutes, get final product with slow fire boiling to 500 milliliter again, decoction liquor is equally divided into to 3 doses.
Medicine of the present invention has blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, and the effect of anti-inflammatory anti-itch, be used for the treatment of the skin pruritus instant effect, and short treating period, do not recur.
Below further set forth the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 20 of rabbit, the male and female dual-purpose, body weight 2kg, divide two groups, and 10 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 30ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, every day twice, serve on 7 days, observes the administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 185 examples for medical treatment, light-duty class 110 examples wherein, heavy class 75 examples.
2, diagnostic criteria
Skin pruritus has dividing of limitation and general property, the initial skin pruritus of generalized pruritus patient only is confined to a place, for light-duty pruritus card, and then extend to gradually large of health or whole body, develop into heavy pruritus card, skin pruritus often for paroxysmal especially to attach most importance to night, owing to constantly scratching, the secondary lesions such as scratch, blood crusts, pigmentation and lichenification appear.The limitation skin pruritus betides a certain position of health, common are pruritus ani, scrotal pruritus, vulval pruritus, capital pruritus disease etc.
3, Therapeutic Method
Select above-mentioned medicament, take to light-duty class patient, each serving with 1 dose, morning every day, respectively take 1 evening, within 10 days, is a course for the treatment of, takes continuously two courses for the treatment of.Take to heavy class patient, each serving with 1 dose, every day, early, middle and late respectively the clothes 1 time, 10 days be a course for the treatment of, takes continuously three courses for the treatment of.
4, efficacy assessment standard
Produce effects: clinical symptom disappearance after treatment, it is normal that skin recovers, and observes half a year without the recidivist;
Take a turn for the better: clinical symptoms is obviously improved, and skin progressively recovers;
Invalid: clinical partial symptoms disappears or, without change, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy skin pruritus patient of the present invention 185 examples, light-duty class 110 examples wherein, produce effects 105 examples as a result, obvious effective rate is 95.45%, 4 examples that take a turn for the better, improvement rate is 3.64%, invalid 1 example, total effective rate is 99.09%; Treat heavy class 75 examples, produce effects 65 examples, obvious effective rate is 86.67%, 8 examples that take a turn for the better, improvement rate is 10.67%, invalid 2 examples, total effective rate is 97.34%.

Claims (3)

1. a medicine for the treatment of skin pruritus, it is characterized in that: it is to be made by the crude drug in the following weight scope:
Radix Polygoni Multiflori 15-25 gram Flos Sophorae 10-20 gram Rhizoma Paridis 10-20 gram
Fructus Aurantii (parched) 15-25 gram Pericarpium Citri Reticulatae 10-20 gram Rhizoma Imperatae 10-20 gram
Semen Ziziphi Spinosae (parched) 20-30 gram Periostracum Cicadae 8-12 gram Cortex Cinnamomi 10-20 gram
Radix Ophiopogonis 10-20 gram Fructus Mori 8-12 cron Radix Gentianae 15-25 gram
Fructus Ligustri Lucidi 10-20 gram Radix Angelicae Sinensis 10-20 gram Poria cum Radix Pini 20-30 gram
Radix Salviae Miltiorrhizae 8-12 gram Radix Rehmanniae Preparata 10-20 gram Zaocys 10-20 gram
Radix Gentianae Macrophyllae 8-12 gram Semen Sesami Nigrum 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Polygoni Multiflori 20 gram Flos Sophorae 15 gram Rhizoma Paridis 15 grams
Fructus Aurantii (parched) 15 gram Pericarpium Citri Reticulatae 15 gram Rhizoma Imperatae 15 grams
Semen Ziziphi Spinosae (parched) 25 gram Periostracum Cicadae 10 gram Cortex Cinnamomi 15 grams
Radix Ophiopogonis 15 gram Fructus Mori 10 cron Radix Gentianae 20 grams
Fructus Ligustri Lucidi 15 gram Radix Angelicae Sinensis 12 gram Poria cum Radix Pini 25 grams
Radix Salviae Miltiorrhizae 10 gram Radix Rehmanniae Preparata 15 gram Zaocys 10 grams
Radix Gentianae Macrophyllae 10 gram Semen Sesami Nigrum 15 grams.
3. according to the preparation method of claim 1 or 2 described medicine, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Radix Polygoni Multiflori: choose decontamination, clean, saturating with blister to eighty per cant, to pull out, profit is even to inside and outside humidity, and section or dice, dry;
(2) Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
(3) Rhizoma Paridis: get crude drug, remove impurity, slightly soak, clean, run through, cut sheet, drying, sieve removes chip;
(4) Fructus Aurantii (parched): get wheat bran and be spread in the heat pot, when the yellow skin of waiting is smoldered, add the Fructus Aurantii sheet, fry to faint yellow, take out, sieve removes wheat bran, cools, and 100 jin of every Fructus Aurantii sheets, with 10 jin, wheat bran;
(5) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, softens, and shredding, dry or cold drying, sieve dedust bits;
(6) Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dry, the clean chip of winnowing with a dustpan;
(7) Semen Ziziphi Spinosae (parched): get clean Semen Ziziphi Spinosae, put in pot and fry to crust and heave and be micro-yellow with slow fire, take out, cool;
(8) Periostracum Cicadae: choose decontamination, clean and dry;
(9) Cortex Cinnamomi: choose clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, by warm water, infiltrates a moment, and section, dry;
(10) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, after running through, pump the heart, then clean and dry;
(11) Fructus Mori: wash, choose decontamination, extract long handle, dry;
(12) Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
(13) Fructus Ligustri Lucidi: choose decontamination, clean, dry;
(14) Radix Angelicae Sinensis: choose decontamination, clean, moistening, slightly dry in the air when suitable to inside and outside humidity, and section is dried;
(15) Poria cum Radix Pini: get crude drug, remove impurity, section, dry in the shade;
(16) Radix Salviae Miltiorrhizae: choose clean impurity, remove rhizome, clean, pull out, run through rear section, dry;
(17) Radix Rehmanniae Preparata: select clean Radix Rehmanniae Preparata to get final product;
(18) Zaocys: get crude drug, brush away ash bits, the used time decaptitates, squama, cutting;
(19) Radix Gentianae Macrophyllae: choose decontamination, except removing LU, slightly soak, run through section, dry;
(20) Semen Sesami Nigrum: get crude drug, remove impurity, sieve removes chip;
(2) preparation
Add 1500 ml waters to soak 60 minutes the Radix Polygoni Multiflori of described weight, Flos Sophorae, Rhizoma Paridis, Fructus Aurantii (parched), Pericarpium Citri Reticulatae, Rhizoma Imperatae, Semen Ziziphi Spinosae (parched), Periostracum Cicadae, Cortex Cinnamomi, Radix Ophiopogonis, Fructus Mori, Radix Gentianae, Fructus Ligustri Lucidi, Radix Angelicae Sinensis, Poria cum Radix Pini, Radix Salviae Miltiorrhizae, Radix Rehmanniae Preparata, Zaocys, Radix Gentianae Macrophyllae, Semen Sesami Nigrum, intense fire decocts boiling 30 minutes, get final product with slow fire boiling to 500 milliliter again, decoction liquor is equally divided into to 3 doses.
CN2012103074559A 2012-08-27 2012-08-27 Drug for curing cutaneous pruritus and preparation method thereof Expired - Fee Related CN102805825B (en)

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CN103705629B (en) * 2014-01-07 2016-03-16 王先忠 A kind of Chinese medicine composition for the treatment of pruritus
CN106377606A (en) * 2016-12-16 2017-02-08 张永红 Medicament for treating skin pruritus and preparation method of medicament

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CN101099774A (en) * 2007-07-10 2008-01-09 尹克华 Chinese herbal medicine special for treating cutaneous pruritus by wind-dispelling and itching-relieving decoction
CN101642546B (en) * 2009-06-14 2011-05-25 李承平 Chinese patent medicine for eliminating toxin and beautifying faces
CN101810800A (en) * 2010-05-26 2010-08-25 泰一和浦(北京)中医药研究院有限公司 Chinese medicinal composition for treating skin itch and preparation method thereof

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