CN103705629B - A kind of Chinese medicine composition for the treatment of pruritus - Google Patents

A kind of Chinese medicine composition for the treatment of pruritus Download PDF

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CN103705629B
CN103705629B CN201410005478.3A CN201410005478A CN103705629B CN 103705629 B CN103705629 B CN 103705629B CN 201410005478 A CN201410005478 A CN 201410005478A CN 103705629 B CN103705629 B CN 103705629B
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radix
chinese medicine
pruritus
fructus
medicine composition
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CN103705629A (en
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王先忠
董艳丽
王军红
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王先忠
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Abstract

The present invention relates to a kind of Chinese medicine composition for the treatment of pruritus, its raw material of Chinese medicine and weight are: Radix Arnebiae (Radix Lithospermi) 5-25 part, Fructus Kochiae 5-25 part, Radix Angelicae Sinensis 10-30 part, Radix Saposhnikoviae 5-25 part, Radix Gentianae Macrophyllae 5-20 part, Radix Sophorae Flavescentis 10-30 part, Indigo Naturalis 5-25 part, Radix Puerariae 5-25 part, Cortex Moutan 5-20 part, Cortex Phellodendri 5-20 part, Radix Rehmanniae 10-30 part, Flos Sophorae 5-25 part, Radix Rehmanniae Preparata 10-30 part, Flos Lonicerae 10-40 part, Fructus Forsythiae 5-20 part, Rhizoma Chuanxiong 5-20 part, Fructus Xanthii 5-25 part, Radix Angelicae Dahuricae 10-30 part, Rhizoma Et Radix Notopterygii 5-20 part, Fructus Gardeniae 5-25 part, Radix Scutellariae 5-20 part, Herba Schizonepetae 5-20 part, Radix Glycyrrhizae 5-15 part.Chinese medicine composition of the present invention has clearing away heat and expelling wind, detoxifying and relieving itching, activating blood circulation to dissipate blood stasis, effect that cold expelling Eradicates is wet, and its treatment pruritus is evident in efficacy, reliable effect.

Description

A kind of Chinese medicine composition for the treatment of pruritus
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of pruritus.
Background technology
Pruritus (pruritus) is a kind of conscious pruritus and clinically without the dermatosis of primary lesion, is one of common clinically dermatosis, is especially more common in old people.It is characterized by based on pruritus, and without primary lesion.Limitation and general two kinds can be divided into clinically.The cause of disease of pruritus is varied, thinks relevant with some disease, as diabetes, hepatopathy, nephropathy etc. more; Also stimulate relevant with some extraneous factors, as cold, warm, chemical & blended fabric etc. simultaneously.At present, doctor trained in Western medicine is take antihistamine drug and tranquilizer for the whole body therapeutic of pruritus, and whole body pruritus person can select vein Calciofon or sodium thiosulfate, also can select procaine intravenous block therapy; Topical therapeutic can external carbolic acid, thymol Calamine Lotion, Dacroment lotion or Emulsion, Mentholum ointment, anaesthesine ointment, capsaicin frost or glucocorticoid cream or ointment etc.Though said medicine has certain effect to antipruritic, it is basic to control.
The traditional Chinese medical science is thought, pruritus belongs to " pruritus ", " pruritus caused by wind pathogen " category.How because natural disposition is not resistance to, defend outer mistake solid, deficient qi and blood, raw dry humorously, and failure of skin and muscle to be nourished causes.
According to theory of Chinese medical science, for the pathogeny of pruritus, with clearing away heat and expelling wind, detoxifying and relieving itching, activating blood circulation to dissipate blood stasis for the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
There is the deficiency of curing the symptoms, not the disease to overcome prior art western medicines in treatment pruritus, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of pruritus that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of pruritus, it is characterized in that: its raw material of Chinese medicine and weight are: Radix Arnebiae (Radix Lithospermi) 5-25 part, Fructus Kochiae 5-25 part, Radix Angelicae Sinensis 10-30 part, Radix Saposhnikoviae 5-25 part, Radix Gentianae Macrophyllae 5-20 part, Radix Sophorae Flavescentis 10-30 part, Indigo Naturalis 5-25 part, Radix Puerariae 5-25 part, Cortex Moutan 5-20 part, Cortex Phellodendri 5-20 part, Radix Rehmanniae 10-30 part, Flos Sophorae 5-25 part, Radix Rehmanniae Preparata 10-30 part, Flos Lonicerae 10-40 part, Fructus Forsythiae 5-20 part, Rhizoma Chuanxiong 5-20 part, Fructus Xanthii 5-25 part, Radix Angelicae Dahuricae 10-30 part, Rhizoma Et Radix Notopterygii 5-20 part, Fructus Gardeniae 5-25 part, Radix Scutellariae 5-20 part, Herba Schizonepetae 5-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of pruritus, is characterized in that: its raw material of Chinese medicine and weight are: Radix Arnebiae (Radix Lithospermi) 15 parts, the Fructus Kochiae 15 parts, Radix Angelicae Sinensis 20 parts, Radix Saposhnikoviae 15 parts, Radix Gentianae Macrophyllae 12 parts, Radix Sophorae Flavescentis 20 parts, Indigo Naturalis 15 parts, Radix Puerariae 15 parts, Cortex Moutan 12 parts, Cortex Phellodendri 10 parts, 20 parts, the Radix Rehmanniae, 15 parts, Flos Sophorae, 20 parts, Radix Rehmanniae Preparata, Flos Lonicerae 30 parts, Fructus Forsythiae 10 parts, Rhizoma Chuanxiong 10 parts, Fructus Xanthii 15 parts, the Radix Angelicae Dahuricae 20 parts, Rhizoma Et Radix Notopterygii 10 parts, Fructus Gardeniae 15 parts, Radix Scutellariae 10 parts, Herba Schizonepetae 12 parts, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Arnebiae (Radix Lithospermi) has effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, removing toxic substances rash; The Fructus Kochiae has effect of clearing away heat-damp and promoting diuresis, relieving stranguria by diuresis; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; Effect that Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely; Radix Gentianae Macrophyllae has effect of Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat; Radix Sophorae Flavescentis has effect of heat clearing and damp drying, wind dispelling insecticide; Indigo Naturalis has effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion; Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, antipyretic effect of promoting the production of body fluid; Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Effect that Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging removes steaming, detoxification sore treatment; The Radix Rehmanniae has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Flos Sophorae has effect of cooling blood for hemostasis, purging liver-fire; Radix Rehmanniae Preparata has effect of yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating; Fructus Forsythiae has effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Fructus Xanthii has dispersing wind and cold, clearing the nasal passage, wind-damp dispelling, antipruritic effect; The Radix Angelicae Dahuricae has effect of the cold expelling that induces sweat, expelling pathogenic wind and restoring the functions of orifices in face, promoting blood circulation and stopping pain, dampness leukorrhagia stopping, detumescence and apocenosis; Rhizoma Et Radix Notopterygii has effect of loose exterior cold, wind-damp dispelling, sharp joint, pain relieving; Fructus Gardeniae has effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Radix Scutellariae has effect of heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention; Effect that Herba Schizonepetae has the loose wind that induces sweat, rash disappears skin ulcer; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays clearing away heat and expelling wind, detoxifying and relieving itching, activating blood circulation to dissipate blood stasis, effect that cold expelling Eradicates is wet altogether, reaches treating both the principal and secondary aspects of a disease to the treatment of pruritus.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 94%, cure rate 69%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
embodiment 1
Treat a Chinese medicine composition for pruritus, its raw material of Chinese medicine and weight proportion are: Radix Arnebiae (Radix Lithospermi) 15g, Fructus Kochiae 15g, Radix Angelicae Sinensis 20g, Radix Saposhnikoviae 15g, Radix Gentianae Macrophyllae 12g, Radix Sophorae Flavescentis 20g, Indigo Naturalis 15g, Radix Puerariae 15g, Cortex Moutan 12g, Cortex Phellodendri 10g, Radix Rehmanniae 20g, Flos Sophorae 15g, Radix Rehmanniae Preparata 20g, Flos Lonicerae 30g, Fructus Forsythiae 10g, Rhizoma Chuanxiong 10g, Fructus Xanthii 15g, Radix Angelicae Dahuricae 20g, Rhizoma Et Radix Notopterygii 10g, Fructus Gardeniae 15g, Radix Scutellariae 10g, Herba Schizonepetae 12g, Radix Glycyrrhizae 6g.
embodiment 2
Treat a Chinese medicine composition for pruritus, its raw material of Chinese medicine and weight proportion are: Radix Arnebiae (Radix Lithospermi) 10g, Fructus Kochiae 25g, Radix Angelicae Sinensis 15g, Radix Saposhnikoviae 25g, Radix Gentianae Macrophyllae 10g, Radix Sophorae Flavescentis 30g, Indigo Naturalis 5g, Radix Puerariae 25g, Cortex Moutan 10g, Cortex Phellodendri 20g, Radix Rehmanniae 15g, Flos Sophorae 25g, Radix Rehmanniae Preparata 10g, Flos Lonicerae 35g, Fructus Forsythiae 5g, Rhizoma Chuanxiong 20g, Fructus Xanthii 10g, Radix Angelicae Dahuricae 25g, Rhizoma Et Radix Notopterygii 5g, Fructus Gardeniae 25g, Radix Scutellariae 5g, Herba Schizonepetae 20g, Radix Glycyrrhizae 12g.
embodiment 3
Treat a Chinese medicine composition for pruritus, its raw material of Chinese medicine and weight proportion are: Radix Arnebiae (Radix Lithospermi) 5g, Fructus Kochiae 20g, Radix Angelicae Sinensis 10g, Radix Saposhnikoviae 20g, Radix Gentianae Macrophyllae 15g, Radix Sophorae Flavescentis 25g, Indigo Naturalis 10g, Radix Puerariae 20g, Cortex Moutan 5g, Cortex Phellodendri 15g, Radix Rehmanniae 10g, Flos Sophorae 20g, Radix Rehmanniae Preparata 15g, Flos Lonicerae 25g, Fructus Forsythiae 12g, Rhizoma Chuanxiong 15g, Fructus Xanthii 5g, Radix Angelicae Dahuricae 30g, Rhizoma Et Radix Notopterygii 12g, Fructus Gardeniae 20g, Radix Scutellariae 15g, Herba Schizonepetae 5g, Radix Glycyrrhizae 8g.
embodiment 4
Treat a Chinese medicine composition for pruritus, its raw material of Chinese medicine and weight proportion are: Radix Arnebiae (Radix Lithospermi) 20g, Fructus Kochiae 10g, Radix Angelicae Sinensis 25g, Radix Saposhnikoviae 5g, Radix Gentianae Macrophyllae 10g, Radix Sophorae Flavescentis 15g, Indigo Naturalis 20g, Radix Puerariae 5g, Cortex Moutan 15g, Cortex Phellodendri 12g, Radix Rehmanniae 25g, Flos Sophorae 5g, Radix Rehmanniae Preparata 25g, Flos Lonicerae 10g, Fructus Forsythiae 15g, Rhizoma Chuanxiong 12g, Fructus Xanthii 20g, Radix Angelicae Dahuricae 15g, Rhizoma Et Radix Notopterygii 15g, Fructus Gardeniae 10g, Radix Scutellariae 12g, Herba Schizonepetae 15g, Radix Glycyrrhizae 10g.
embodiment 5
Treat a Chinese medicine composition for pruritus, its raw material of Chinese medicine and weight proportion are: Radix Arnebiae (Radix Lithospermi) 25g, Fructus Kochiae 5g, Radix Angelicae Sinensis 30g, Radix Saposhnikoviae 10g, Radix Gentianae Macrophyllae 20g, Radix Sophorae Flavescentis 10g, Indigo Naturalis 25g, Radix Puerariae 10g, Cortex Moutan 20g, Cortex Phellodendri 5g, Radix Rehmanniae 30g, Flos Sophorae 10g, Radix Rehmanniae Preparata 30g, Flos Lonicerae 15g, Fructus Forsythiae 20g, Rhizoma Chuanxiong 5g, Fructus Xanthii 25g, Radix Angelicae Dahuricae 10g, Rhizoma Et Radix Notopterygii 20g, Fructus Gardeniae 5g, Radix Scutellariae 20g, Herba Schizonepetae 10g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of pruritus given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 100 example, man 57 example, female 43 example, 15 ~ 70 years old age.
Two, diagnostic criteria:
1. the whole body or the violent pruritus of local skin, without former skin lesion;
2. after repeatedly scratching because of pruritus, secondary skin lesion can be caused, as scratch, blood crusts, pigmentation etc.;
3. old people and adult send out well, and winter or summer is common.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within five days, is a course for the treatment of.Treatments period is avoided cold and uncooked food, the thing of pungent, stimulation.
Four, criterion of therapeutical effect:
(1) fully recover: sings and symptoms disappears or substantially disappears;
(2) effective: sings and symptoms major part takes a turn for the better;
(3) effective: a sings and symptoms part takes a turn for the better;
(4) invalid; Sings and symptoms is all not improved, and symptom is as front.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-5 the course for the treatment of, and recovery from illness 69 example, follows up a case by regular visits to and have no recurrence; Effective 17 examples, effective 8 examples, invalid 6 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
Chen, female, 32 years old.Whole skin pruritus, xerosis cutis and a large amount of desquamation, scratch is obvious, and scratching tear has blood crusts, accompanies vexed, and xerostomia is had a sleepless night, large dry stool.Examine and see: the white or few tongue of red tongue with thin fur, thready pulse or count accurately.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, pruritus obviously alleviates, other transference cures; Continue to take 2 courses for the treatment of, pruritus disappears, free movement of the bowels, recovery from illness.Follow up a case by regular visits to after half a year without recurrence.
Case 2:
Grandson, man, 47 years old.Private prosecution time medical: whole body skin pruritus 2 years, autumn and winter increases the weight of.During morbidity, unbearably, pachylosis is dry for extremity pruritus, and sleeping and eating difficulty peace, is hard and dry.Various desensitizer, vitamin drug for oral administration etc., and external hormones ointment, poor effect.Take 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, all symptoms disappear completely, recovery from illness.
Case 3:
Zhao, man, 63 years old.Patient's readme: whole body skin pruritus is not repeatedly more more than 3 years, and unbearably, dizzy knee joint is soft, and tinnitus is as Cicadae for whole body pruritus.Once took multi-medicament treatment, effect is all not good.Examine and see: whole skin dries up coarse, have bran shape desquamation, skin lesion major part is all plump, and with extremity, back for work, on it, diffusivity is covered with scratch and blood crusts.Red tongue, tongue are few, stringy and thready pulse.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, conscious gargalesthesia alleviates, and xerosis cutis desquamation is clearly better; Continue to take 3 courses for the treatment of, all diseases disappear, and cure.Follow up a case by regular visits to after half a year without recurrence.

Claims (1)

1. treat a Chinese medicine composition for pruritus, it is characterized in that: its raw material of Chinese medicine and weight proportion are: Radix Arnebiae (Radix Lithospermi) 15g, Fructus Kochiae 15g, Radix Angelicae Sinensis 20g, Radix Saposhnikoviae 15g, Radix Gentianae Macrophyllae 12g, Radix Sophorae Flavescentis 20g, Indigo Naturalis 15g, Radix Puerariae 15g, Cortex Moutan 12g, Cortex Phellodendri 10g, Radix Rehmanniae 20g, Flos Sophorae 15g, Radix Rehmanniae Preparata 20g, Flos Lonicerae 30g, Fructus Forsythiae 10g, Rhizoma Chuanxiong 10g, Fructus Xanthii 15g, Radix Angelicae Dahuricae 20g, Rhizoma Et Radix Notopterygii 10g, Fructus Gardeniae 15g, Radix Scutellariae 10g, Herba Schizonepetae 12g, Radix Glycyrrhizae 6g.
CN201410005478.3A 2014-01-07 2014-01-07 A kind of Chinese medicine composition for the treatment of pruritus Expired - Fee Related CN103705629B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108014202A (en) * 2016-11-01 2018-05-11 上海珈凯生物科技有限公司 A kind of traditional Chinese medicine extract composition with anti-skin irritatin effect and preparation method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1172674A (en) * 1997-08-29 1998-02-11 刘进成 Chinese medicinal herb composition for treating skin disease
CN1214261A (en) * 1998-10-21 1999-04-21 余际康 Oral medicine for curing dermatosis
US20070160689A1 (en) * 2006-01-12 2007-07-12 Everett Laboratories, Inc. Compositions and methods for treatment of coughing, sneezing, rhinorrhea, and/or nasal obstruction
CN102068635A (en) * 2010-12-31 2011-05-25 谭曜 Traditional Chinese medicine for treating refractory pruritus
US20120223157A1 (en) * 2011-03-02 2012-09-06 Leslie Marie Radentz Botanical formulation derived from birch bark
CN102805825A (en) * 2012-08-27 2012-12-05 兰恒志 Drug for curing cutaneous pruritus and preparation method thereof
CN103479929A (en) * 2013-09-23 2014-01-01 荣成市科学技术情报研究所 Traditional Chinese medicine composition for treating pruritus

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1172674A (en) * 1997-08-29 1998-02-11 刘进成 Chinese medicinal herb composition for treating skin disease
CN1214261A (en) * 1998-10-21 1999-04-21 余际康 Oral medicine for curing dermatosis
US20070160689A1 (en) * 2006-01-12 2007-07-12 Everett Laboratories, Inc. Compositions and methods for treatment of coughing, sneezing, rhinorrhea, and/or nasal obstruction
CN102068635A (en) * 2010-12-31 2011-05-25 谭曜 Traditional Chinese medicine for treating refractory pruritus
US20120223157A1 (en) * 2011-03-02 2012-09-06 Leslie Marie Radentz Botanical formulation derived from birch bark
CN102805825A (en) * 2012-08-27 2012-12-05 兰恒志 Drug for curing cutaneous pruritus and preparation method thereof
CN103479929A (en) * 2013-09-23 2014-01-01 荣成市科学技术情报研究所 Traditional Chinese medicine composition for treating pruritus

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