CN103041262B - Traditional Chinese medicine enema for curing chronic prostatitis and preparing method thereof - Google Patents

Traditional Chinese medicine enema for curing chronic prostatitis and preparing method thereof Download PDF

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CN103041262B
CN103041262B CN201210585691.7A CN201210585691A CN103041262B CN 103041262 B CN103041262 B CN 103041262B CN 201210585691 A CN201210585691 A CN 201210585691A CN 103041262 B CN103041262 B CN 103041262B
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fructus
enema
herba
chronic prostatitis
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韩韬
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Hubei Daokang Medical Technology Co ltd
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Qingdao Huaren Technology Incubator Co Ltd
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Abstract

The invention provides a traditional Chinese medicine enema for curing chronic prostatitis, which is prepared from the following bulk drugs in part by weight: 10-20 parts of orobanche coerulescens, 10-20 parts of poria cocos, 10-20 parts of seeds of cowherb, 10-20 parts of schisandra chinensis, 10-20 parts of herba epimedii, 10-20 parts of seeds of Chinese dodder, 10-20 parts of fructus alpiniae oxyphyllae, 10-20 parts of dogwood, 10-20 parts of oldenlandia diffusa. 10-20 parts of dandelion, 10-20 parts of prepared fleece flower root, 10-20 parts of semen plantaginis, 10-20 parts of roots of red-rooted salvia, 10-20 parts of golden cypress, 10-20 parts of rhizoma alismatis, 10-20 parts of selfheal, 10-20 parts of fructus cnidii, 10-20 parts of patrinia, 10-20 parts of Scutellaria baicalensis, 10-20 parts of roots of common peony, 10-20 parts of rhizoma smilacis glabrae, 10-20 parts of raspberry, 10-20 parts of moutan bark and 10-20 parts of Caulis Spatholobi. The traditional Chinese medicine enema and the method adopt traditional Chinese medicines of promoting blood circulation to remove blood stasis, improve capillary permeability and alleviate inflammatory response.

Description

A kind of Chinese medicinal enema for the treatment of chronic prostatitis and preparation method thereof
Technical field
The present invention relates to contain the medicinal preparation that derives from plant, animal or mineral component, particularly a kind of Chinese medicinal enema for the treatment of chronic prostatitis and preparation method thereof.
Background technology
Chronic prostatitis is the common a kind of disease of male reproductive system, and how relevant with the factor such as excessive consumption of alcohol, surfeit irritable food, sitting saddle chair, constipation, minority is thoroughly not cured by acute prostatitis.But most patient had not had the acute inflammation stage, this type of patient's prostatic fluid often has pathogenic bacterium.Chronic prostatitis can cause infertility, posterior urethritis, cystitis, bladder neck sclerosis, severe jamming patient's quality of life.Brought great mental burden to patient, many patients merge psychasthenia, lack confidence to curing.
Chronic prostatitis belongs to the traditional Chinese medical science " essence is turbid ", " gonorrhea " category, its main pathogenesis be wound damp and hot, drink, pungent excessively, smooth, the caused by energy stagnation and blood stasis of impairment caused by overstrain vital essence, vascular, make damp and hot viscid, qi and blood stagnation, deficiency of kidney-QI, knot, melts respectively or mutually pathogenic mutually, due to most, without obvious pathogenic bacterium, doctor trained in Western medicine curative effect is poor.Extract oral effect is slow.
The traditional Chinese medical science thinks that its cause of disease one is for having a liking for food cigarette, wine, pungent, delicious food savoury, impairing the spleen and stomach, and wine is raw damp and hot, the multiple abscess part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels; Two is intemperate sexual intercourse, directly contamination, and damp and hot poison is evil to drive in the wrong direction, and stations the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels; Three is the impacts such as society and environmental factors, medium stimulation, and libido can not get normal catharsis, frequent masturbation, and intemperate sexual intercourse, bears essence not let out, and causes prostate repeatedly congested, and retention of corruptive essence essence chamber accumulates wine poison of a specified duration, hinders in meridians; Or feelings will is not smooth, depressed rage impairing the liver, irritability is lost in catharsis, hematogenous blockage and cause coagulation of QI-blood for a long time, coagulation of QI-blood can increase the weight of again that damp and hot poison is evil to be formed, both reciprocal causations.The symptom of chronic prostatitis varies with each individual, and is mainly divided into following two kinds: a kind of is pain symptom, containing around hypogastric region, lumbosacral region, anus, the position pain such as perineal position and testis, penis; Another kind is the discomfort of urinating, and it is white etc. that as unable in urine retention, frequent micturition, urgent micturition, urine, urine drips.General Symptoms is mainly that anxiety, energy are not concentrated, lassitude, also can be attended by sexual function abnormal, as ejaculate too fast, erection is not hard, hyposexuality etc.
Prostatitis divides acute bacterial, chronic bacillary and non-bacterial etc. dissimilar.Its pathogeny is that antibacterial infects; Staphylococcus epidermidis immunoreation; Arthritis, iritis, urethra instrumental examination, catheter are placed, and upper respiratory tract, urinary system infection, sexual function change or eating and drinking without temperance, and susceptible to anger frequently causes retention of damp-heat in the interior, loses smart turbid corruption, causes body of gland inflammation, abscess.The classical symptom of acute stage is that feel cold heating, fervescence, nausea and vomiting, urine urgency-frequency, dysurea turbid urine, constipation, perineal position and lower back portion distending pain, prostate swells and ache.The clinical manifestation of chronic phase be dizzy dizzy, waist is ached, urine urgency-frequency, discharge mucus, hyposexuality, impotence and premature ejaculation, painful and swollen testis prostatitis disease after urinating endless, urinate and have complicated symptoms, course of disease delay, obstinate difficult more, the feature such as easy recurrence.Traditional medicine application eliminating damp-heat, pyretic toxicity is treating stranguria, and method multipotency proves effective.
Chronic prostatitis is male person between twenty and fifty's commonly encountered diseases, frequently-occurring disease, and in the male more than 36 years old, chronic prostatitis prevalence can be up to 35%-37%.Slow to fall ill clinically, etiology and pathology complexity, Symptoms is various, and sign is not true to type, and protracted inflammation shows effect repeatedly, and prolonged difficulty is more feature.Be Drug therapy and naturopathy for the primary treatment method of chronic prostatitis at present, wherein Drug therapy comprises each antibiotics, α receptor blocking agent, immunosuppressant and supplementary zinc and vitamin, and route of administration is for oral administration, injection, rectal perfusion, anus filling, body of gland injection etc.; Wherein naturopathy comprises microwave, muscle electric stimulation, hot water hip-bath, massage of prostate, the four cavities conduit pipe administrations of two capsule, direct injection (per rectum or perineum), medicine iontophoresis.
But adopt above-mentioned Therapeutic Method, patient is comparatively painful, and the treatment persistent period is longer, and effect is not ideal.Various ways above, damage testicular spermatogenic, it is only auxiliary treatment means, even certain methods complicated operation, and problems such as dangerous, cross infection in addition, the suppository of other rectals, unguentum exist that dosage form is unreasonable, compatibility not science, treat poor drawback.But Chinese medicine is being obtained good curative effect aspect treatment chronic prostatitis, especially improving patient's symptom, improve aspect patients ' life quality and there is obvious advantage, and expense is cheaper, in recent years, more and more receive the concern of this area research worker about the prostatitic medicine for the treatment of by Chinese herbs and research.
Summary of the invention
Technical problem to be solved by this invention is, existing Therapeutic Method, and patient is comparatively painful, and the treatment persistent period is longer, and effect is not ideal.Damage testicular spermatogenic, it is only auxiliary treatment means, even certain methods complicated operation, and problems such as dangerous, cross infection in addition, the suppository of other rectals, unguentum exist that dosage form is unreasonable, compatibility not science, treat poor drawback; Chinese medicine decoction is oral, although there are some curative effects, curative effect is not good enough, take effect slow, and drug manufacture cost is higher, and manufacturing cycle is longer, and drug absorption rate is low.
For solving these technical barriers, the invention provides a kind of Chinese medicinal enema for the treatment of chronic prostatitis, described in it, in Chinese medicinal enema, the parts by weight of various crude drug can be: 10~20 parts of Herba Orobanchess, 10~20 parts, Poria, 10~20 parts of Semen Vaccariae, 10~20 parts of Fructus Schisandrae Chinensis, 10~20 parts of Herba Epimedii, 10~20 parts of Semen Cuscutae, 10~20 parts of Fructus Alpiniae Oxyphyllae, 10~20 parts of Fructus Corni, 10~20 parts of Herba Hedyotidis Diffusaes, 10~20 parts of Herba Taraxacis, 10~20 parts of Radix Polygoni Multiflori Preparata, 10~20 parts of Semen Plantaginiss, 10~20 parts of Radix Salviae Miltiorrhizaes, 10~20 parts of Cortex Phellodendris, 10~20 parts of Rhizoma Alismatis, 10~20 parts of Spica Prunellaes, 10~20 parts of Fructus Cnidiis, 10~20 parts of Herba Patriniae, 10~20 parts of Radix Scutellariaes, 10~20 parts of Radix Paeoniae Rubra, 10~20 parts of Rhizoma Smilacis Glabraes, 10~20 parts of Fructus Rubies, 10~20 parts of Cortex Moutans, 10~20 parts of Caulis Spatholobis.
The Chinese medicinal enema of described treatment chronic prostatitis, described in it, in Chinese medicinal enema, the parts by weight of various crude drug can also be: 10~15 parts of Herba Orobanchess, 10~15 parts, Poria, 10~15 parts of Semen Vaccariae, 10~15 parts of Fructus Schisandrae Chinensis, 10~15 parts of Herba Epimedii, 10~15 parts of Semen Cuscutae, 10~15 parts of Fructus Alpiniae Oxyphyllae, 10~15 parts of Fructus Corni, 10~15 parts of Herba Hedyotidis Diffusaes, 10~15 parts of Herba Taraxacis, 10~15 parts of Radix Polygoni Multiflori Preparata, 10~15 parts of Semen Plantaginiss, 10~20 parts of Radix Salviae Miltiorrhizaes, 10~20 parts of Cortex Phellodendris, 10~20 parts of Rhizoma Alismatis, 10~20 parts of Spica Prunellaes, 10~20 parts of Fructus Cnidiis, 10~20 parts of Herba Patriniae, 10~20 parts of Radix Scutellariaes, 10~20 parts of Radix Paeoniae Rubra, 10~20 parts of Rhizoma Smilacis Glabraes, 10~20 parts of Fructus Rubies, 10~20 parts of Cortex Moutans, 10~20 parts of Caulis Spatholobis.
The Chinese medicinal enema of described treatment chronic prostatitis, described in it, in Chinese medicinal enema, the parts by weight of various crude drug can be also: 10~20 parts of Herba Orobanchess, 10~20 parts, Poria, 10~20 parts of Semen Vaccariae, 10~20 parts of Fructus Schisandrae Chinensis, 10~20 parts of Herba Epimedii, 10~20 parts of Semen Cuscutae, 10~20 parts of Fructus Alpiniae Oxyphyllae, 10~20 parts of Fructus Corni, 10~20 parts of Herba Hedyotidis Diffusaes, 10~20 parts of Herba Taraxacis, 10~20 parts of Radix Polygoni Multiflori Preparata, 10~20 parts of Semen Plantaginiss, 10~15 parts of Radix Salviae Miltiorrhizaes, 10~15 parts of Cortex Phellodendris, 10~15 parts of Rhizoma Alismatis, 10~15 parts of Spica Prunellaes, 10~15 parts of Fructus Cnidiis, 10~15 parts of Herba Patriniae, 10~15 parts of Radix Scutellariaes, 10~15 parts of Radix Paeoniae Rubra, 10~15 parts of Rhizoma Smilacis Glabraes, 10~15 parts of Fructus Rubies, 10~15 parts of Cortex Moutans, 10~15 parts of Caulis Spatholobis.
For solving the problems of the technologies described above, the present invention also provides a kind of preparation method of Chinese medicinal enema for the treatment of chronic prostatitis, and its preparation process comprises:
A. described crude drug is mixed, chopping, sieves, and soaks.
B. the crude drug of immersion being added to alcohol heating reflux extracts 2 times;
C. get again the medicinal residues after above-mentioned ethanol extraction, the heating and refluxing extraction that adds water 2 times;
D. above-mentioned two kinds of extracting solution are merged to decompression recycling ethanol disinfectant preparation.
In described step a, chopping after can first described crude drug being mixed, XianCheng's coarse powder, further pulverize, cross 120 mesh sieves, the fine powder amount that enable pass is crossed 120 mesh sieves is reaching 30%, collect that to obtain fine powder by the fine powder of 120 mesh sieves for subsequent use, unsifted coarse granule is placed on and in ethanol, soaks 8-12 hour.
In described step b, can just soaked crude drug coarse granule heating and refluxing extraction 2 times, each 1~2 hour, 2 extracting solution are merged and left standstill.
In described step c, add water heating and refluxing extraction 2 times of the medicinal residues that above-mentioned ethanol extraction can be crossed, each 1~2 hour, merges 2 extracting solution to leave standstill.
In described steps d, above-mentioned two kinds of extracting solution can be merged, 1.35 filtrate when concentrating under reduced pressure relative density is 80 DEG C, reclaims ethanol, and gained filtrate is adjusted to proportion to 1.06, and the paste materials that reduces pressure to obtain, with ultraviolet, disinfection, becomes enema.
For solving the problems of the technologies described above, the present invention provides a kind of preparation method of Chinese medicinal enema for the treatment of chronic prostatitis again, and its preparation method further can comprise:
A, get crude drug and put into ethanol and soak, heat is extracted 2 times, becomes paste, is component 1;
B, medicinal residues extracting in water 2 times, thickening filtration is paste, is component 2;
C, above-mentioned two kinds of pastes are merged into enema.
In described step a, can get in the ethanol that crude drug adds 5-10 doubly to measure and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, merge extractive liquid,, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, heating is concentrated into paste, and stand for standby use, becomes component 1; In described step b, the medicinal residues that ethanol extraction is crossed are put into 10 times of water gagings, heating and refluxing extraction 2 times, each extraction time is 1~2 hour, and 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, heating is concentrated into paste, and stand for standby use, becomes component 2; In described step c, above-mentioned two kinds of component paste concentrated solutions can be merged, then use ultraviolet, disinfection, becomes enema.
The using method of enema of the present invention: choose crude drug, can prepare enema by the method that the invention provides embodiment, also can decoct as medicine soup 150-120ml with clear water 500ml, get supernatant cool to medicine temperature for 30-40 DEG C of left and right, after advising patient's defecation, get lateral position, with the about 20cm of anal canal insertion anus, inhale medicinal liquid with 50ml syringe and slowly pour into (or using transfusion device infusion) capable retention enema of rectum from anal canal, flat sleeping 30 minutes of slightly padded buttocks after coloclysis, every day coloclysis 1 time, treating 10 days was 1 course for the treatment of.When per rectum administration, medicine can absorb 50%~70% at rectum, and does not directly enter 3 Venous systems of pelvic cavity viscera by liver, makes prostate rehabilitation rapidly under medicine effective concentration effect.
From anatomical angle, the anatomical position of prostate and rectum is adjacent, and part has abundant blood vessel to be communicated with, and prostate peripheral lymphoid host will be at prostate rear, and part lymph net and rectum have abundant traffic.Therefore, herbal retention enema can make medicine absorb by rectal mucosa, and can there be higher concentration in through sick institute in the prostate of pathological changes, and therapeutic effect is more satisfactory, has also avoided some untoward reaction of oral medication and intravenous administration simultaneously.
The useful technique effect of the present invention is: adopt blood circulation promoting and blood stasis dispelling Chinese herbal medicine, can improve capillary permeability, reaction reduces inflammation, promote disappearing and absorbing of inflammation focus, improve connective tissue metabolism, can promote conversion and the absorption of preneoplastic lesions, can make again the connective tissue rehabilitation of atrophy.When per rectum administration, medicine can absorb at rectum, and does not directly enter 3 Venous systems of pelvic cavity viscera by liver, makes prostate rehabilitation rapidly under medicine effective concentration effect.Enema can make medicine absorb by rectal mucosa, and can there be higher concentration in through sick institute in the prostate of pathological changes, and therapeutic effect is more satisfactory, has also avoided some untoward reaction of oral medication and intravenous administration simultaneously.The present invention is cheap, and preparation method is simple and easy to do, can create good social benefit and economic benefit.
Detailed description of the invention
Chronic prostatitis is one of Urology Surgery commonly encountered diseases, and Chinese medicine is without this name of disease, but according to its sings and symptoms, the turbid sick category of genus traditional Chinese medical science essence, how by due to blood stasis due to renal deficiency.Oral and intravenous pharmacy can not penetrate capsula prostatica well, and how undesirable therapeutic effect is.With Kidney-Invigorating & Blood-Activating Herbs per rectum administration assistant treatment chronic prostatitis, not only can absorb and bring into play drug effect at intestinal wall by medicinal liquid, also can promote the effect of oral and intravenously administrable, strengthen curative effect, thereby make patients with chronic prostatitis early recovery.
The chronic prostatitis traditional Chinese medical science is called " nebulousurine ", " essence is turbid ", " Plain Questions regulating menstruation opinion ": few sun is in spring, and visitor's victory, very descends albiduria white." beautiful machine is really hidden opinion ": stuffy feverish sensation in the lower abdomen and disease goes out white." miscellaneous diseases source and course rhinoceros candle five types of stranguria reddish and whitish turbid urine source and course ": excessive in vain, heat stagnation disease also, a legendary venomous insect.The kidney pulse passes through ridge, genus kidney, and network bladder, therefore lower abdomen injustice heat and pain are urinated out white liquid also, accordingly, spleen is subject to ailment said due to cold or exposure and passes in kidney, wind energy is incited heat, therefore accumulation of pathogenic heat in the interior, very essence is not kept, and thing is swum excessive and is gone out in vain." nephropathy from therapy stranguria with turbid discharge from therapy nebulousurine from the beginning of autotherapy ": after urine, ooze out seminal fluid, if water from washing rice is as slurry, superficial, its nebulousurine, belongs to due to the heat of bladder water channel more.Prostatitis is not rarely seen in ancient times, and there is more perfect discussion, the traditional Chinese medical science is thought, its pathogenic factor is mainly damp and hot descending, and stagnant heat hinders in the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, so that smart road is unfavorable and sick, its TCM Syndrome Type is with varied, but recently relevant scholar's research finds that chronic prostatitis is taking damp-heat type, blood stasis type as main, and occur merge of two cards morely, reached 78.59% of total case load.
Modern medicine is found after deliberation, chronic prostatitis is apt to occur in person between twenty and fifty, cause prostata tissue chronic congestion and edema in the sexual maturity stage because of libido excessively or frequently, pathological manifestations is that prostata tissue inflammation sample becomes, but seldom has the massive inflammatory cells infiltrated due to pathogenic infection.
Traditional medicine thinks, chronic prostatitis renal deficiency type basic pathogenesis is kidney asthenia as the principal aspect, and blood stasis is auxiliary.Coloclysis Chinese medicine is for pathogenesis, taking invigorating kidney, promoting blood circulation as Therapeutic Principle.When chronic prostatitis, due to prostate inflammatory plumpness, urethra after compressing, causes that urine is smooth, drop deficient, wish solution must not be separated, and affects antibiotic and infiltrates scorching district and play a role.
Modern pharmacological research confirmation, drug for invigorating blood circulation and eliminating stasis can improve capillary permeability, and the reaction that reduces inflammation promotes disappearing and absorbing of inflammation focus, improves connective tissue metabolism, can promote conversion and the absorption of preneoplastic lesions, can make again the connective tissue rehabilitation of atrophy.When per rectum administration, medicine can absorb 50%-70% at rectum, and does not directly enter 3 Venous systems of pelvic cavity viscera by liver, makes prostate rehabilitation rapidly under medicine effective concentration effect.From anatomical angle, the anatomical position of prostate and rectum is adjacent, and part has abundant blood vessel to be communicated with, and prostate peripheral lymphoid host will be at prostate rear, and part lymph net and rectum have abundant traffic.Therefore, herbal enema can make medicine absorb by rectal mucosa, and can there be higher concentration in through sick institute in the prostate of pathological changes, and therapeutic effect is more satisfactory, has also avoided some untoward reaction of oral medication and intravenous administration simultaneously.
Herba Orobanches QI invigorating yin fluid astringing in side, helps QI invigorating to give birth to the power of the moon; Radix Angelicae Sinensis is nourshing Yin and drynsessmoistening prescription, clearing heat and relieving fidgetness; Herba Hedyotidis Diffusae, Cortex Moutan heat-clearing and toxic substances removing, eliminating dampness and astringing sores, reinforcing spleen and kidney; Radix Salviae Miltiorrhizae medicine carrying is up, makes the efficacy of a drug up, can qi and blood circulation promotion, and all medicines are grown and oiliness, mend and do not stay the stasis of blood; Spica Prunellae antiinflammatory blood stasis dispelling, removing heat from blood coordinating the actions of various ingredients in a prescription; All medicines share mends double the executing of row, plays altogether benefiting qi and nourishing yin and nourishes blood, the merit of promoting flow of QI and blood pain relieving.Fructus Cnidii bactericidal antiphlogistic, Radix Scutellariae removing heat from blood toxin expelling, evacuation of pus, expelling pus and promoting granulation; Herba Orobanches, Semen Plantaginis anti-inflammation and sterilization, effect that the foster skin of invigorating blood circulation, heat-clearing and toxic substances removing, granulation promoting are put on flesh, Radix Polygoni Multiflori Preparata, Herba Epimedii the kidney invigorating and essence nourishing, treatment impotence and premature ejaculation, the moon Sanguis Draxonis that declines; The good medicine of the weak deficiency of YIN of gas; Poria, Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, Radix Paeoniae Rubra heat clearing away; All medicines have share spleen invigorating eliminating dampness by diuresis, effect that heat-clearing and toxic substances removing, eliminating dampness and astringing sores, granulation promoting are put on flesh, can improve capillary permeability, reaction reduces inflammation, promote disappearing and absorbing of inflammation focus, improve connective tissue metabolism, can promote conversion and the absorption of preneoplastic lesions, can make again the connective tissue rehabilitation of atrophy.
The micro-hardship of Spica Prunellae, liver heat removing, eliminating stagnation, diuresis; Control the diseases such as pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension; Control that lymphoid tuberculosis, thyromegaly, scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia are shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Spica Prunellae is the key medicine of clearing away liver-fire, Disperse hepatic depression, and what it cured mainly is the disease of Liver Channel mostly.This product is equipped with Flos Chrysanthemi, Semen Cassiae, can liver heat removing and eyesight improving, and control conjunctival congestion and swelling pain, be equipped with Concha Haliotidis, Ramulus Uncariae Cum Uncis, can pancake liver-yang, control headache, dizziness; Be equipped with the product such as Radix Scrophulariae, Bulbus Fritillariae Uninbracteatae, Concha Ostreae, can hard masses softening and resolving, control scrofula and go through tuberculosis." the southern regions of the Yunnan Province book on Chinese herbal medicine ": the liver-wind of dispelling, the network of passing through, controls facial hemiparalysis.Row irritability, opens stagnation of liver-QI, only bones and muscles pain, ophthal malgia, and loose scrofula is stolen, whole body tuberculosis.
Herba Hedyotidis Diffusae is again Herba Hedyotidis Diffusae, two leaves, Herba Commelinae Bengalensis, Chinese Lobelia.Mildly bitter flavor, sweet, cold.Enter stomach, large intestine, small intestine meridian, clearing up internal heat by using drugs of bitter in taste and cold in nature removing toxic substances, sweet cold eliminating damp-heat, has stronger removing toxicity for eliminating carbuncles effect to carbuncle, pharyngalgia, snakebite etc.Be generally used for treatment sore, laryngopharynx swelling and pain, abdominalgia with intestinal abscess, venom, also for the puckery pain of pyretic stranguria, dysuria.The good medicine of damp eliminating of drawing out pus by applying a plaster to the affected part.
Radix Scutellariae has heat clearing and damp drying, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.We are used in fungal culture miscellaneous bacteria and infect special severity by the strong feature of broad-spectrum antibacterial action, fine by Radix Scutellariae extracting solution effect." Bencao Jingshu ": Radix Scutellariae, its property is respectful clearly, so evil removing: so bitter in the mouth dampness; So YIN-cold victory heat, therefore main all heat.All hot persons, pathogenic heat with all over heat also, jaundice, intestinal be out-of-the-way, let out dysentery, the disease of all damp and hot victory also, is analysed it, all diseases are from recover.Bitter cold can be except damp and hot, thus small intestinal profit and water from by, source is clearly flowed also clean.The blood person of closing, excess-heat is at blood system, and amenorrhea is made us obstructed in instant heating human blood chamber, damp and hot solution, Ying Qi is clearly and voluntarily also.Malignant boil cellulitis erosion person, heat in blood is stayed knot, and is that carbuncle stain is also rotten: acute scleritis person, fire of moxibustion blood trouble also, removing heat from blood heat extraction, spontaneous recovery also.Radix Scutellariae has antiallergic action and antiinflammatory action: the contained baicalin of Radix Scutellariae and baicalin can obviously suppress the anaphylaxis contractile response that sensitized guinea pig rat small intestine in vitro and isolated tracheal produce antigen, passive general allergy to Cavia porcellus and mice and Cavia porcellus passivity skin allergic reaction, baicalin and baicalin also have inhibitory action.Radix Scutellariae has refrigeration function, most evidences, and the active ingredient baicaligenin of Radix Scutellariae has refrigeration function.Radix Scutellariae has Detoxication, and baicalin has obvious Detoxication, and this may be that baicalin decomposites glucuronic acid due under the effect of glucuronidase, and due to being combined with multiple poisonous substance.10 milligrams of LD 50 that can improve strychnine of baicalin reach 2.5 times, and the hepatic glycogen content of carbon tetrachloride poisoning mice is increased.
Chinese medicine Radix Polygoni Multiflori have Radix Polygoni Multiflori and Radix Polygoni Multiflori Preparata point, direct slicing is used as medicine for Radix Polygoni Multiflori, mixes after steaming and dries and be used as medicine for Radix Polygoni Multiflori Preparata with Semen sojae atricolor liquor.The function of the two is different: the removing toxic substances of Radix Polygoni Multiflori function, eliminating carbuncle, loosening bowel to relieve constipation, be usually used in treating scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; The invigorating the liver and kidney of Radix Polygoni Multiflori Preparata function, benefiting essence-blood, black beard and hair, bone and muscle strengthening, for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void etc.Radix Polygoni Multiflori Preparata of the present invention is the good merchantable brand of invigrating kidney.
Radix Salviae Miltiorrhizae hardship, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen caking, skin infection swells and ache, the tumbling down pain of injury, menoxenia, amenorrhea dysmenorrhea, puerperal stasis of blood pain etc.Treatment costa sternales pain, lump in the abdomen caking, and menoxenia, amenorrhea dysmenorrhoea have good effect.. " detailed outline " carries: Radix Salviae Miltiorrhizae, and by " the sensible opinion of married woman " cloud, SIWU TANG is controlled gynecopathy, pays no attention to antenatal puerperal, how many through water, all can be general, only taste Radix Salviae Miltiorrhizae is loose, cures mainly identical with it.Lid Radix Salviae Miltiorrhizae can break stagnated blood, mends fresh blood, peaceful tire, the stillborn fetus that falls, only metrorrhagia dysentery, regulating menstruation arteries and veins.
Semen Cuscutae Gan Xinping, enters liver, kidney channel.The kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, antiabortive.For caused by liver and kidney deficiency, soreness of waist and knee joint, impotence and seminal emission, frequent urination and enuresis, two blurred visions are dark, the diseases such as frequent fetal movement.Function tonification Liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.Suffer from a deficiency of the kidney and rush down for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen.
Herba Epimedii is pungent, sweet, warm, returns liver, kidney channel.Energy reinforcing the kidney and supporting YANG, strengthening the tendons and bones, expelling wind and removing dampness, is apt to control insufficiency of kidney-YANG, impotence and seminal emission, enuresis frequent micturition; Rheumatic arthralgia, atrophic debility of bones paralysis disease." book on Chinese herbal medicine is stated " cloud " excessive sheep fire, the main impotence of " herbal classic " medicine is hindered absolutely, and " solar corona " be its treatment of head speech man sun absolutely also, and woman is cloudy absolutely, and calling into the gate of vitality, benefit kidney-Yang person is also.The lid gate of vitality be the kidney-Yang in kidney, the vigour of the person also, the exhausted YANG exhaustion the moon of its what is called, the not vigour of basis, how hiss in both withered.So-called physical strength profiting, Qiang Zhi, and control cold air consumptive disease, and the anxious card that waits of muscles and bones contraction, all it helps the event of vigour.Old man's dusk octogenarian, the middle age is forgetful, all Yuanyang decay and can not ascensionist also.Must know that this taste is to reduce to liter, its liter is owing to falling also.”
Fructus Cnidii is pungent, bitter, temperature; Slightly poisonous.Return kidney channel.Cure mainly warming the kidney to invigorate YANG, dampness, dispels the wind, parasite killing.For sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis is gynecological external use good medicine." Bencao Jingshu " carries: Fructus Cnidii, and bitter in the mouth is flat; " not Lu " be pungent sweet nontoxic; Modern its abnormal smells from the patient in detail, when the warm-dryness syndrome of must holding concurrently, sun also.Therefore swell and ache in housewife people's the moon, man's impotence pruritus due to damp pathogen, except stagnated QI, sharp joint, malignant boil." not Lu " warming the middle warmer and descending qi, makes married woman's Zifu heat, and man is cloudy strong, has made us son.Lid can dehumidify with tongue, and temperature can cold expelling, pungently can moisten kidney, sweet can strengthening the spleen, therefore can remove all deficiency and coldness of married woman man disease of viscera connecting with this channel that wets.Cold-damp was both removed, and disease is gone, performance Yiyang, thus disease, and have tonification also.
Fructus Schisandrae Chinensis temperature; Sour, sweet; Return lung, the heart, kidney channel; Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia." Bencao Jingshu " carries: the main QI invigorating person of Fructus Schisandrae Chinensis, and all gas of lung master, acid can be received, and is just entering lung tonifying the lung, therefore QI invigorating is also.Its main cough with dyspnea person, the deficiency of vital energy is above stopped up and is not returned unit, and sour flavor having the property of astringing, takes the photograph gas and returns unit, and cough with dyspnea is from removing.Impairment caused by overstrain is won thin, tonifying for the deficiency, reinforcing YIN-essence, beneficial man's essence." not Lu " supports the five internal organs, heat extraction, and flesh person in raw the moon, the special the kidney invigorating of Fructus Schisandrae Chinensis, the tonifying five ZANG-organs of holding concurrently, kidney storing essence, essence is contained cloudy strong, receive to take the photograph vital qi and return unit, and public region is warm, and digesting food, steams waste matter and changes precise and tinyly, smart spontaneous, and essence is raw cloudy long, therefore main as above all diseases are also.
Herba Patriniae nature and flavor are bitter flat, have effect of heat-clearing and toxic substances removing, evacuation of pus removing blood stasis with potent drugs.Can cure acute appendicitis, dysentery, leucorrhea with red and white discharge, the stagnant stomachache of the stasis of blood in puerperal, conjunctival congestion and swelling pain.Enter stomach, large intestine, Liver Channel.Cure mainly heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the breast abdomen pain due to the excess-heat stasis of blood is stagnant, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.
Herba Orobanches reinforcing the kidney and supporting YANG, bone and muscle strengthening.For sexual neurasthenie, lassitude loin and legs; Infantile diarrhea is controlled in external, enteritis, dysentery." Kaibao Bencao ": main man's five kinds of strain and seven kinds of impairment, mend waist kidney, make us son, remove wind blood.But Herba Orobanches can reduce ANAE+ lymphocyte percentage in the time of high concentration or low concentration.Can find out that kidney-reinforcing drug Herba Orobanches can promote Ea bow structure to form under finite concentration, E rosette test is the common method of measuring human T-cell's quantity, can reflect to a certain extent the cellular immune function of body.
Poria sweet in the mouth, light, property are flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.For dysuria, disease Poria function promoting diuresis to eliminate damp pathogen such as edema, and the property of medicine is gentle, diuretic and do not hinder healthy energy, is promoting diuresis to eliminate damp pathogen key medicine.The disease of all dysuria, retention of water-damp, no matter be partial to cold-damp, or relatively damp and hot, or belong to insufficiency of the spleen wet poly-, all can fit applications.As cold-damp person relatively, can with the compatibility such as Ramulus Cinnamomi, the Rhizoma Atractylodis Macrocephalae; Be partial to damp and hot person, can with the compatibility such as Polyporus, Rhizoma Alismatis; The person that belongs to deficiency of spleen-QI, can with the compatibilities such as Radix Codonopsis, Radix Astragali, the Rhizoma Atractylodis Macrocephalae; Belong to deficiency and coldness person, also can join Radix Aconiti Lateralis Preparata, the Rhizoma Atractylodis Macrocephalae is equal to use.
Fructus Corni, cures mainly pathogen cold and heat under the heart, and warming middle-JIAO, by cold warm numbness, goes three worms, the merit that for a long time clothes have been made light of one's life by commiting suicide reinforcing YIN-essence benefit essence, settling five organs, logical nine orifices, stopped dribbling urination; Take for a long time improving eyesight, brute force all the year round.Fructus Corni, has another name called Fructus Corni, medicine Fructus Jujubae, real Fructus Jujubae, Fructus Corni, meat Fructus Jujubae etc., is the conventional rare Chinese medicine of China, and applicating history is long.It is gentle with its benefit power, tonifying YANG and do not help fire, YIN nourishing and oiliness diaphragm, convergence and do not stay the evil special efficacy that waits by successive dynasties use that medical science is liked.Zhang Zhongjing has been formulated " JINGUI SHENQI WAN " taking Fructus Corni as monarch.According to chemical analysis, Fructus Corni contains the effective ingredient such as cornin, tartaric acid, gallic acid, malic acid, resin, tannin and the multivitamin that physiologically active is stronger, having the immunity, antiinflammatory of enhancing, the pharmacological action such as antibacterial, is Herba indigoferae Pseudotinctoriae conventional in tcm clinical practice.
Semen Vaccariae is pinkwort Vaccaria segetalis Vaccariasegetalis(neck) dry seed of Garcker, there is promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain, expedites the emergence of the function of stimulating milk secretion.Cure mainly menoxenia, agalactosis, difficult labour, the diseases such as carbuncle furunculosis, are the important medicines of clinical conventional stimulating milk secretion." herbal classic ": main incised wound, hemostasis, by pain, goes out thorn, except migratory arthralgia endogenous cold.2. not " not Lu ": stop vexed epistaxis, carbuncle malignant boil, flaccidity breast, married woman's difficult labour.
Fructus Alpiniae Oxyphyllae: Latin formal name used at school, Fructus Alpinae Oxyphyllae.Temperature compensation astringency inducing, warm spleen antidiarrheal is taken the photograph saliva, and the kidney warming controlling nocturnal emission with astringent drugs reducing urination, cures mainly spleen-kidney vacuity cold, abdominal pain diarrhea; Or kidney qi deficiency and coldness frequent micturition, the enuresis, seminal emission, nebulousurine; Or chronic diarrhea due to Deficiency and coldness of spleen and stomach and mouthful in saliva outflow and can not effector.Fructus Alpiniae Oxyphyllae is containing volatile oil, Fructus Alpiniae Oxyphyllae ketone, vitamin B1, vitamin B2, vitamin C, vitamin E and several amino acids, fatty acid etc.Fructus Alpiniae Oxyphyllae decoct has the effect of stomach invigorating, diuresis, minimizing salivation.Its water extract has the ascitogenous sarcoma of inhibition S180.The effect of cell enlargement.Its water extract and ethanol extraction have the effect that suppresses ileum contraction.In addition, its methanolic extract has the effect such as activity of exempting from aorta and shrink and suppress prostaglandin synthetase that strengthens left atrium contractility, suppresses that potassium chloride causes.
In Herba Taraxaci Herba Taraxaci plant, contain the multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin, have the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Herba Taraxaci contains protein, fat, carbohydrate, trace element and vitamin etc. simultaneously, has abundant nutritive value, raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.Dandelion Compositae belongs to herbaceos perennial.It is the plant of dietotherapeutic.Record according to Compendium of Material Medica, the flat sweet and slightly bitter taste of its property, has heat-clearing and toxic substances removing, dispersing swelling and dissipating binds and galgctogogue action, very effective to treatment mastitis.No matter decoct juice oral, or smash to mud external application, effect all had.In addition, Herba Taraxaci also has the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting, is widely used in clinical.Compendium of Material Medica has a cloud: " the tender Seedling of Herba Taraxaci is edible, eats that to control infectious disease especially good raw." the successive dynasties Medical monographs such as Shennong's Herbal, Tang Materia Medica, " Chinese medicine voluminous dictionary " all gives high evaluation.
Semen Plantaginis returns lung meridian; Liver Channel; Kidney channel; Urinary bladder channel.Function: clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Cure mainly: main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily.Diuresis, normal person is taken Semen Plantaginis decoct 10g orally, has diuresis, but enters decoct total capacity and every day the water yield all without recording, and lacks strictly contrast.Normal person and rabbit take Herba Plantaginis seed decoct without obvious diuresis.Plantago depressa Willd seed is also without diuresis." Japan hanako materia medica ": diuresis drenches puckery, tonifying YANG.Control de-essence, vexed.The therapeutic method to keep the adverse QI flowing downwards.
Rhizoma Alismatis (rhizome) is one of traditional Chinese medicine.Theory of Chinese medical science thinks that it is cold in nature, has effect of promoting diuresis to eliminate damp pathogen.Modern medicine study, Rhizoma Alismatis can reduce serum total cholesterol and triacylglycerol content, slows down atherogenesis; Rhizoma Alismatis and preparation modern times thereof are also used for the treatment of auditory vertigo, dyslipidemia, seminal emission, fatty liver and diabetes etc.The fat-soluble part of Rhizoma Alismatis has obvious cholesterol reducing effect and study of anti-atherogenic effect to experimental hypercholesterolemicrabbits rabbit, by wherein separate Alisol A, B and Alisol A, the acetas of B, C, except alisol B, there is the cholesterol reducing effect showing.Add with 0.1% content in the feedstuff of experimental atherosclerosis rats, can make cholesterolemia decline more than 50%, wherein the strongest with the effect of Alisol A-24-acetas.The ethanol extraction of Rhizoma Alismatis, the ethyl acetate extract of ethanol extract etc., have effect for reducing blood fat to experimental hypercholesterolemicrabbits rabbit and rat.It is the strongest that ethyl acetate extract and its are insoluble to residual fraction effect in acetic acid one water.Ethyl acetate extract oral 1g/kg every day, also has obvious cholesterol reducing effect to raising with the normal rat of normal diet.Prove by coordination list notation method, Alisol A has the ability that suppresses mouse small intestine esterified cholesterol, and can make the absorbance of cholesterol in rat small intestine reduce by 34%, but does not affect linoleic absorption.
Radix Paeoniae Rubra, clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control that the stagnant amenorrhea of the stasis of blood, hernia abdominal mass gather, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.The Radix Paeoniae Rubra point excess-heat that can purify the blood, dissipating blood stasis blood is detained.This product function is close with Cortex Moutan, therefore normal and Cortex Moutan mutual reinforcement between are use.But the effect of Cortex Moutan clearing away heat and cooling blood is better, point excess-heat that can purify the blood, can control again fever due to yin deficiency; And Radix Paeoniae Rubra can only be used for blood system excess-heat, be good at promoting blood circulation to remove blood stasis." herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Rhizoma Smilacis Glabrae nature and flavor: sweet light, flat.Gui Jing: Liver Channel; Stomach warp; Spleen channel.Function: removing toxic substances, dehumidifying, sharp joint.Cure mainly: control syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, treats furuncle, carbuncle, scrofula, the limbs contracture due to syphilis and mercurialism, bones and muscles pain. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": control five types of stranguria nebulousurine, double syphilitic sore, the erysipelas controlled." detailed outline ": strengthening the spleen and stomach, bone and muscle strengthening, curing rheumatism, sharp joint, stopping leak rushes down.Control contracture osteodynia; Malignant boil carbuncle.Separate hydrargyrum powder, Vermilion poison.
Fructus Rubi is warm in nature; Sweet, sour; Return kidney, urinary bladder channel.Cure mainly: kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination.For enuresis due to deficiency of the kidney, frequent micturition, impotence and premature ejaculation, emission and spermatorrhea." Bencao Jingshu ": " Fructus Rubi, its main QI invigorating person, says beneficial vital essence also.Kidney storing essence, kidney improving inspiration by invigorating kidney-QI, vital essence abundance, body, from light, is sent out in vain not also.The respectful main tonify deficiency of reviving is absolutely continuous, reinforcing YIN-essence Jianyang, smoothing skin, peace and internal organs.The main man's kidney-jing deficiency of Zhen Quan exhausts, impotence, woman's food have a son.Large bright main settling five organs, beneficial color, supports vital essence, long hair, Qiang Zhi.All get its kidney tonifying and add essence, the adopted ear of sweet acid convergence." " property of medicine opinion " carry its: " main man's kidney-jing deficiency exhausts, woman's food have a son.Main impotence.″
Cortex Moutan.Compendium of Material Medica is carried it: " nourishing YIN to lower pathogenic fire is separated speckle poison, throat, diuresis stasis.Descendant specially controls fire mutually with yellow tiller, does not know that the merit of Cortex Moutan more wins also.Red colored person's profit, the person of spending in vain mends, and people also seldom realizes, and should distinguish it." modern study, contained paeonol and glucosides constituents in addition thereof all have antiinflammatory action; The methanolic extract of male Cortex Moutan has inhibition Platelet; Paeonol has the effects such as the central inhibitory actions such as calmness, cooling, antipyretic, analgesia, spasmolytic and atherosclerosis, diuresis, antiulcer.
Caulis Spatholobi property hardship, sweet, temperature.Return liver, kidney channel, enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation, supplementary Amplifications of the Compendium of Materia Medica carries it can cure numb hand and foot; Quadriplegia; Rheumatic arthralgia; Women has through uncomfortable; Dysmenorrhea.
Cortex Phellodendri heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency." Chinese Pharmacopoeia " carries the power of Cortex Phellodendri heat clearing and damp drying, similar to Radix Scutellariae, Rhizoma Coptidis, but damp and hot as good taking except the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels.
Embodiment 1: the manufacturing process of enema of the present invention is: by Herba Orobanches 1000g, Poria 1000g, Semen Vaccariae 1000g, Fructus Schisandrae Chinensis 1000g, Herba Epimedii 1000g, Semen Cuscutae 1000g, Fructus Alpiniae Oxyphyllae 1000g, Fructus Corni 1000g, Herba Hedyotidis Diffusae 1000g, Herba Taraxaci 1000g, Radix Polygoni Multiflori Preparata 1000g, Semen Plantaginis 1000g, Radix Salviae Miltiorrhizae 1000g, Cortex Phellodendri 1000g, Rhizoma Alismatis 1000g, Spica Prunellae 1000g, Fructus Cnidii 1000g, Herba Patriniae 1000g, Radix Scutellariae 1000g, Radix Paeoniae Rubra 1000g, Rhizoma Smilacis Glabrae 1000g, Fructus Rubi 1000g, Cortex Moutan 1000g, Caulis Spatholobi 1000g.First described crude drug is ground into coarse powder, more further pulverizes, cross 120 mesh sieves, the fine powder amount that enable pass is crossed 120 mesh sieves is reaching 30%, collects and obtains fine powder a by the fine powder of 120 mesh sieves; Can not drop into multi-function extractor by the coarse powder of 120 mesh sieves again and extract twice, and add for the first time 8-10 and doubly measure ethanol decoction 1-2 hour, and add for the second time 4-8 times of water gaging and decoct 1-2 hour, merge twice decocting liquid, filter to get filtrate; Heating is concentrated into pasty state, becomes enema after ultraviolet radiation for sterilizing and disinfecting.
Embodiment 2: the manufacturing process of enema of the present invention can also be: by Herba Orobanches 1500g, Poria 1500g, Semen Vaccariae 1500g, Fructus Schisandrae Chinensis 1500g, Herba Epimedii 1500g, Semen Cuscutae 1500g, Fructus Alpiniae Oxyphyllae 1500g, Fructus Corni 1500g, Herba Hedyotidis Diffusae 1500g, Herba Taraxaci 1500g, Radix Polygoni Multiflori Preparata 1500g, Semen Plantaginis 1500g, Radix Salviae Miltiorrhizae 1000g, Cortex Phellodendri 1000g, Rhizoma Alismatis 1000g, Spica Prunellae 1000g, Fructus Cnidii 1000g, Herba Patriniae 1000g, Radix Scutellariae 1000g, Radix Paeoniae Rubra 1000g, Rhizoma Smilacis Glabrae 1000g, Fructus Rubi 1000g, Cortex Moutan 1000g, Caulis Spatholobi 1000g.Mix, chopping, soaks.Just soaked crude drug heating and refluxing extraction 2 times, each 1~2 hour, merges 2 extracting solution to leave standstill.The medicinal residues of more above-mentioned water extraction being crossed add 5~8 times of amount 60~70% alcohol heating reflux and extract 2 times, each 1~2 hour, 2 extracting solution are merged and are left standstill.Above-mentioned two kinds of extracting solution are merged, and concentrating under reduced pressure relative density is the filtrate of 1.35 (80 DEG C), reclaims ethanol, and gained filtrate is adjusted to proportion to 1.06, and the extractum that reduces pressure to obtain, with can directly using after ultraviolet radiation for sterilizing and disinfecting.
Embodiment 3: the preparation method of enema of the present invention can be also: by Herba Orobanches 1000g, Poria 1000g, Semen Vaccariae 1000g, Fructus Schisandrae Chinensis 1000g, Herba Epimedii 1000g, Semen Cuscutae 1000g, Fructus Alpiniae Oxyphyllae 1000g, Fructus Corni 1000g, Herba Hedyotidis Diffusae 1000g, Herba Taraxaci 1000g, Radix Polygoni Multiflori Preparata 1000g, Semen Plantaginis 1000g, Radix Salviae Miltiorrhizae 1500g, Cortex Phellodendri 1500g, Rhizoma Alismatis 1500g, Spica Prunellae 1500g, Fructus Cnidii 1500g, Herba Patriniae 1500g, Radix Scutellariae 1500g, Radix Paeoniae Rubra 1500g, Rhizoma Smilacis Glabrae 1500g, Fructus Rubi 1500g, Cortex Moutan 1500g, Caulis Spatholobi 1500g mixes, the water soaking 1-2 hour that adds 5-10 doubly to measure, extract 2 times, heating extraction 1-2 hour, is concentrated into extractum shape, becomes component 1, residue medicinal residues add 60-90% soak with ethanol 0.5-1.5 hour, extract twice, each 1-2 hour, merge extractive liquid,, filters, concentrated, 80-160 order filters, and the 6000-10000 rev/min of supernatant after centrifugal, is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, ultrafiltrate concentrating under reduced pressure relative density is the extractum of 1.35 (80 DEG C), heating and refluxing extraction 2 times, each 30 minutes~45 minutes, extracts active ingredient, 2 extracting solution are merged and are settled into extractum shape, as component 2.After merging, with ultraviolet, sterilize.
Herbal enema can make medicine absorb by rectal mucosa, and can there be higher concentration in through sick institute in the prostate of pathological changes, and therapeutic effect is more satisfactory, has also avoided some untoward reaction of oral medication and intravenous administration simultaneously.
Pharmacology's toxicity test
One, antibacterial experiment
In body, antibacterial tests result shows, enema of the present invention has significant protective effect to the animal of escherichia coli and Bacillus proteus, can subtract the development of the state of an illness, reduces the mortality rate of animal; In-vitro antibacterial experimental result shows, prostatitis urinary system bolt has antibacterial and bactericidal action in various degree to the antibacterial of urinary system infection; The prostatitic experimental result that affects of experimental rat is shown, the present invention can infect the weightening finish of prostate body of gland afterwards by anti-bacteria, slows down the development of the state of an illness, and the pathomorphism that suppresses prostata tissue changes; After administration, within 2-5 hour, can make the urine amount of animal obviously increase; Obvious cooling effect in 5 hours after the rabbit body temperature rising administration that fresh yeast is caused; The animal auricular concha swelling that xylol causes and granuloma induced by implantation of cotton pellets tissue is had to obvious inhibitory action, and suppress the increase of capillary permeability; The pain that chemical substance stimulating animal peritoneum or thermal stimulus animal body surface are caused has certain inhibitory action.
Two, animal acute toxicity test research:
When the present invention adopts rectally approach, the maximum dosage-feeding on the one that records mice is 62.7g/kg (in medicated powder), be about 1567.5 times (people is in 60kg) intending clinical people's consumption, the maximum dosage-feeding 62.7g/kg (in medicated powder) on the one of rat, is about and intends 1567.5 times of clinical people's consumption.The equal Continuous Observation of laboratory animal one week, its outward appearance sign, the mental status, diet, drinking-water, feces etc. are showed no obvious abnormalities.When experiment finishes, animal is healthy survival all, and body weight increases.
Three, long-term toxicity test for animals research:
It is high that medicine of the present invention is established in this test, in, low dose group and substrate matched group, blank group, adopt rectally approach to give rat, dosage is respectively 3.2, 2.4 and 1.6g/kg (in medicated powder), be equivalent to intend 80 of clinical patient consumption [0.04g (medicated powder)/kg], 60 and 40 times, successive administration 2 months, in administration process, the body weight of each administration group and matrix group rat, dietary amount, outward appearance sign, behavioral activity, the mental status, hair color, feces character and the comparison of blank group, no significant difference (P > 0.05), the weight of animals increasing value and Main Organ Coefficients and blank group comparing difference be remarkable (P > 0.05) not, hematology and the indivedual indexs of blood parameters check result administration group and blank group comparing difference be (P < 0.05) significantly, but convalescent period finishes rear discrepant hematology and blood parameters has all recovered normal, other indexs and blank comparing difference be remarkable (P > 0.05) not, administration phase and convalescent period histological examination high dose group animal main organs and blank group relatively have no notable difference, having no slowness toxicity occurs.
Four, animal local excitation test:
The allergic reaction on guinea pigs of enema of the present invention and Rat-rectum medication irritation test.
Result shows: skin anaphylactic test, high dose group 0.8g (medicated powder)/kg, low dose group 0.1g (medicated powder)/kg, be equivalent to respectively to intend 20 times, 2.5 times of clinical people's consumption [0.04g (medicated powder)/kg], through percutaneous drug delivery, be showed no animal and produce allergy; Rectal application irritation test high dose group 5.0g (medicated powder)/kg, low dose group 3.2g (medicated powder)/kg, be equivalent to respectively to intend 125,80 times of clinical people's consumption, in official hour, observe mucous membrane of rectum all without phenomenons such as hyperemia, edema, histopathologic examination and blank group be no significant difference relatively, have no and occur obvious irritative response, every group of its overall health of patients of Some Animals of retaining, body weight, breathing, circulation, central nervous system and extremity activity etc., all Non Apparent Abnormality reactions.
Pharmacological experiment explanation:
One: Chinese medicinal enema of the present invention carries out the experimental study of anti-prostatic hyperplasia
(1) by SD rat castration subcutaneous injection testosterone 4mg/kg after 7 days, give 0.0938 simultaneously, 0.1875, the Chinese medicinal enema of the present invention (with the method preparation of the embodiment of the present invention 2) of 0.375/kg (is equivalent to 2.5 of clinical plan consumption, 5,10 times), once a day, 7 days weekly, after continuous 5 weeks, put to death and detect.Test shows, the prostate index of big or middle dosage group, prostate dry weight, notopodium weight have significant difference compared with model group, and the prostate volume of heavy dose of group has extremely significant difference compared with model group; Height of glandular epithelium, the lumen caliber of dosage group big or middle have significant difference compared with model group, the acid phosphatase of heavy dose of group, and the DNA content of big or middle dosage group has significant difference compared with model group.Test prompting, Chinese medicinal enema of the present invention has more significant inhibitory action to benign prostatic hyperplasia under this experimental condition.
(2) by SD rat castration subcutaneous injection testosterone 4mg/kg after 7 days, give 0.0938,0.1875 simultaneously, the enema suspension coloclysis of the present invention of 0.375/kg (be equivalent to clinical plan consumption 2.5,5,10 times), once a day, 7 days weekly, after continuous 5 weeks, put to death and detect.The prostate index of dosage group big or middle, prostate dry weight, notopodium weight have significant difference compared with model group, and the prostate volume of heavy dose of group has extremely significant difference compared with model group; Height of glandular epithelium, the lumen caliber of dosage group big or middle have significant difference compared with model group, the acid phosphatase of heavy dose of group, and the DNA content of big or middle dosage group has significant difference compared with model group.Test prompting, enema of the present invention has more significant inhibitory action to benign prostatic hyperplasia under this experimental condition.
(3) kunming mice is planted to the enema suspendible flow container intestinal of the present invention that gives 0.0938,0.1875,0.375g/kg after tire Mus gential sinus and (be equivalent to 2.5 of clinical plan consumption, 5,10 times), once a day, 7 days weekly, after continuous 5 weeks, put to death and detect.The prostate index of heavy dose of group, the notopodium weight of big or middle dosage group, the volume of middle dosage group have significant difference compared with model group; The height of glandular epithelium of dosage group big or middle, the lumen caliber of each dosage group have significant difference compared with model group, and the acid phosphatase of large and small dosage group has significant difference compared with model group.Test prompting, the present invention has more significant inhibitory action to benign prostatic hyperplasia under this experimental condition.
Two, the inhibitory action of the inhibitory action of the swollen hypertrophy of rat granuloma of the present invention to kunming mice pain
1. test objective: observe and give continuously tested material one week, the inhibitory action to the inhibitory action of the swollen hypertrophy of rat granuloma to kunming mice pain.
2. tested material
Chinese medicinal enema of the present invention (making by the embodiment of the present invention 3 methods); The SD rat that animal is provided by Shandong University's Experimental Animal Center, 4 months ages of Mus, body weight: test body weight 362 ± 22 (X ± SD) g.Sex: male; Every treated animal number: each 10; Raising condition: clean level Animal House, 22 ± 2 DEG C of temperature, humidity 45 ± 10%, 12 beats/min of rates of ventilation, feed routine disinfection rat feed, drink disinfectant, gregarious raising, 5, every cage.
Dosage arranges and reason: with reference to developmental pharmacology guideline, and the clinical plan dosage that hospital provides, the 2.25g/d that is grown up, calculates 2.25g/d ÷ 60kg body weight: 0.0375g/kg/d by 60kg body weight.Animals administer amount by 2.5 times of clinical plan consumption, 5 times, 10 times establish little, in, large three dosage groups.(1) small dose group, 0.0375g/kgx2.5 times=0.09375g/kg/d; (2) dosage group in, 0.0375g/kgx5 times=0.1875g/kg/d, 0.0375g/kgx10 times=0.375g/kg/d of (3) heavy dose of group.
3. matched group
A. blank group: the disinfectant soup water that gives same volume; B. QIANLIEKANG group: be equivalent to 5 times of clinical oral administration dosage.Adult 5g/d, calculates by 60kg, i.e. 5g ÷ 60kgx5 times=0.417g/kg/d; Every rat administration capacity 10ml/kg of administration volume, by equivalent different dosing concentration, medicine-feeding way gavage is identical with clinical administration approach.QIANLIEKANG, pharmaceutical Co. Ltd of Kang Enbei group manufactures, commercially available, 60 slices/bottle of specification 0.5g x, quantity, a 3-4 sheet, 3 times on the one, oral.Rayon balls, makes heavy 10 ± 1g, and size is close, and diameter 7mm, uses after autoclave sterilization.
4. test method
4.1 medicine preparations: get the present invention and be configured to high dose group, middle dosage group, small dose group, get QIANLIEKANG 4.17g, is dissolved in 100ml drinking water, is configured to 4.17% concentration.
4.2 animal models: rat, under pentobarbital anesthesia, is tucked in nest and respectively cuts an osculum in left and right, expand subcutaneous tissue by vascular forceps, sterilizing cotton balls is implanted respectively to rat both sides, and to tuck in nest subcutaneous, then sews up, and starts postoperative next day by above-mentioned dosed administration, within the 8th day, weigh, after administration 2 hours, by rat anesthesia, peel off and take out cotton balls granulation tissue, pick fatty tissue to the greatest extent around, 12h at 60 DEG C, dries, and weighs.
4.3 observation index granuloma net weight, deduct raw cotton ball weight by the granuloma weight of oven dry and are granuloma net weight.
4.4 statistical methods adopt OFFICE software, calculate the weight (organizing granulomatous index) of cotton balls under every 100g body weight, calculate its meansigma methods and standard deviation (X ± SD), then carry out significant t-test.
5. result and evaluation, result is as following table.
The impact of tablet of the present invention on the swollen hypertrophy of rat granuloma
Result shows: QIANLIEKANG group of the present invention all has the effect that suppresses chronic granuloma hypertrophy, and enema effect of the present invention is comparatively desirable.
Clinical data
1.1 diagnosis and inclusive criterias
1 clinical data
1.1 physical data
This is organized 40 examples and all meets following diagnostic criteria: a) clinical symptoms is to suppress swollen discomfort, pain as main on perineal position, lumbosacral region and pubis; or there are testis anus, the waist swollen discomfort of acid and pain; sometimes distending pain position is walked not alter fixingly, with frequent micturition, urgent micturition, the urethra scorching hot wherein person such as pain, greasy urine that itches; B) prostatic fluid routine test result shows: lecithin reduces; C) prostatic fluid antibacterial culturing majority is without antibacterial; D) before and after urinating and defecating, urethra overflows white sticky discharge, microscopic hematuria or have leukocyte; E) internal rectum touch prostate has satiety, and matter is soft or soft or hard is uneven, the sense of capsule sample, tenderness slightly, and prostate diminishes, matter is tough.Age of onset is at 25 years old~69 years old, average 45 years old; The course of disease 2 months~20 years, average 10 years.
1.2 Therapeutic Method
Herbal enema, taking heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, spasmolysis and analgesia, detumescence relieving accumulation of pathogens as Therapeutic Principle, is taken the circumstances into consideration plus-minus according to symptom weight.Side is with Herba Orobanches 15g, Poria 10g, Semen Vaccariae 10g, Fructus Schisandrae Chinensis 10g, Herba Epimedii 10g, Semen Cuscutae 12g, Fructus Alpiniae Oxyphyllae 13g, Fructus Corni 14g, Herba Hedyotidis Diffusae 11g, Herba Taraxaci 12g, Radix Polygoni Multiflori Preparata 12g, Semen Plantaginis 11g, Radix Salviae Miltiorrhizae 12g, Cortex Phellodendri 11g, Rhizoma Alismatis 12g, Spica Prunellae 11g, Fructus Cnidii 12g, Herba Patriniae 13g, Radix Scutellariae 11g, Radix Paeoniae Rubra 12g, Rhizoma Smilacis Glabrae 11g, Fructus Rubi 11g, Cortex Moutan 12g, the plus-minuss such as Caulis Spatholobi 11g, every day potion, decocting retention enema, decocts the about 100mL~150mL of juice, and temperature is with 33 DEG C-40 DEG C.Before sleeping every night first by defecation emptying, get left lateral position, on enemator and anus coating liquid paraffin oil a little, by air emptying in enemator pipeline, then, from the anus soft 4cm~8cm that inserts enemator slowly, open enemator, medicinal liquid is slowly poured in rectum, operating time is 2min~5min, and pouring into total amount is 100mL~150mL, and end of operation is closed enemator.Hold letterweight with left hand and live anus, the right hand is slowly extracted enemator.Patient gets right arm reclining, horizontal position, ventricumbent position, left lateral position, seat, semireclining position successively, adjusts position depending on the concrete state of an illness, the about 15min~20min of each position, last semipronation is had a rest, every day coloclysis once, retain a night, 2 weeks~4 weeks course for the treatment of.
2 results
2.1 curative effect determinate standard
Cure: clinical symptoms disappears completely, and prostatic fluid is normal.Effective: clinical cardinal symptom disappears, and prostatic fluid is normal.Effective: clinical symptom relief or disappearance, prostatic fluid routine test improves.Invalid: before and after clinical symptoms treatment, substantially without improving, prostatic fluid routine test is not improved.
2.2 therapeutic outcome
In 40 routine patients, recovery from illness 27 examples, account for 67.5%; Effective 6 examples, account for 15%; Effective 5 examples, account for 12.5%; Invalid 2 examples, account for 5%.
3 discuss
Chronic prostatitis is the common a kind of disease of male reproductive system, and how relevant with the factor such as excessive consumption of alcohol, surfeit irritable food, sitting saddle chair, constipation, minority is thoroughly not cured by acute prostatitis.But most patient had not had the acute inflammation stage, this type of patient's prostatic fluid often has pathogenic bacterium.Chronic prostatitis can cause infertility, posterior urethritis, cystitis, bladder neck sclerosis, severe jamming patient's quality of life.Brought great mental burden to patient, many patients merge psychasthenia, lack confidence to curing.
Chronic prostatitis belongs to the traditional Chinese medical science " essence is turbid ", " gonorrhea " category, its main pathogenesis be wound damp and hot, drink, pungent excessively, smooth, the caused by energy stagnation and blood stasis of impairment caused by overstrain vital essence, vascular, make damp and hot viscid, qi and blood stagnation, deficiency of kidney-QI, knot, melts respectively or mutually pathogenic mutually, due to most, without obvious pathogenic bacterium, doctor trained in Western medicine curative effect is poor.Extract oral effect is slow.The present invention is according to theory of Chinese medical science, dialectical treating, and herbal enema, makes the medicine sick institute that goes directly, and taking promoting flow of QI and blood, heat-clearing and toxic substances removing, relieving spasm to stop pain, detumescence relieving accumulation of pathogens as main, holds concurrently with symptomatic treatments such as vital energy benefiting and the kidney invigorating.Obtain good curative effect.
Detailed description of the invention:
Specific embodiment 1: Lee, man, 43 years old, first visit on October 10 in 2009.Patient tells and often feels that in recent years perineal position, lower abdomen dull pain are not easypro, and per rectum refers to inspection and prostatic fluid chemical examination, is diagnosed as chronic prostatitis, once repeatedly used the antibacterials such as erythromycin, compound sulfamethoxazole, therapeutic effect is undesirable, aggravation closely over the past half year, and sex-linkage hypofunction.Examine quarter: perineal position and lower abdomen dull pain discomfort, after urinating and after an action of the bowels normal adularescent secretions flows out from urethral orifice, sexual hypofunction, giddy, feeling of fullness in the head, weak, tired out, red tongue, lack tongue, root Huang is greasy, thready and stringy pulse.Prostatic fluid chemical examination: erythrocyte (+), leukocyte (++), pus cell is a small amount of.Digital rectal examination: prostate hyperplasia, pain.Medicinal: Herba Orobanches 12g, Poria 10g, Semen Vaccariae 10g, Fructus Schisandrae Chinensis 10g, Herba Epimedii 10g, Semen Cuscutae 12g, Fructus Alpiniae Oxyphyllae 11g, Fructus Corni 12g, Herba Hedyotidis Diffusae 13g, Herba Taraxaci 12g, Radix Polygoni Multiflori Preparata 12g, Semen Plantaginis 11g, Radix Salviae Miltiorrhizae 12g, Cortex Phellodendri 11g, Rhizoma Alismatis 12g, Spica Prunellae 11g, Fructus Cnidii 12g, Herba Patriniae 13g, Radix Scutellariae 11g, Radix Paeoniae Rubra 11g, Rhizoma Smilacis Glabrae 12g, Fructus Rubi 12g, Cortex Moutan 12g, Caulis Spatholobi 13g.Before sleeping every night first by defecation emptying, get left lateral position, on enemator and anus coating liquid paraffin oil a little, by air emptying in enemator pipeline, then, from the anus soft 4cm~8cm that inserts enemator slowly, open enemator, medicinal liquid is slowly poured in rectum, operating time is 2min~5min, and pouring into total amount is 100mL~150mL, and end of operation is closed enemator.Hold letterweight with left hand and live anus, the right hand is slowly extracted enemator.Patient gets right arm reclining, horizontal position, ventricumbent position, left lateral position, seat, semireclining position successively, adjusts position, the about 15min~20min of each position depending on the concrete state of an illness, last semipronation is had a rest, every day coloclysis once, retain a night, it within 10 days, is 1 course for the treatment of, 3 days, interval between the course for the treatment of, after finish 3 courses for the treatment of, above-mentioned symptom is alleviated, check prostatic fluid, normally, clinical cure, follows up a case by regular visits to 2 years without recurrence.
Specific embodiment 2: poplar, man, 32 years old, hobby tobacco and wine, lived irregular, chronic prostatitis, prostate hyperplasia are suffered from readme, symptom for urine line is thin, dysuria, urethral orifice causalgia, and have the symptom such as hyposexuality, sexual impotence, have a strong impact on sleep.Poor effect undergoes various treatments.Prostatic fluid on inspection, 16/HP of leukocyte (high power field under mirror) erythrocyte (-).Medicinal: Herba Orobanches 13g, Poria 10g, Semen Vaccariae 10g, Fructus Schisandrae Chinensis 10g, Herba Epimedii 10g, Semen Cuscutae 12g, Fructus Alpiniae Oxyphyllae 11g, Fructus Corni 13g, Herba Hedyotidis Diffusae 13g, Herba Taraxaci 12g, Radix Polygoni Multiflori Preparata 12g, Semen Plantaginis 11g, Radix Salviae Miltiorrhizae 12g, Cortex Phellodendri 11g, Rhizoma Alismatis 12g, Spica Prunellae 11g, Fructus Cnidii 12g, Herba Patriniae 13g, Radix Scutellariae 11g, Radix Paeoniae Rubra 11g, Rhizoma Smilacis Glabrae 13g, Fructus Rubi 12g, Cortex Moutan 12g, Caulis Spatholobi 14g.Make enema.Before sleeping every night first by defecation emptying, get left lateral position, on enemator and anus coating liquid paraffin oil a little, by air emptying in enemator pipeline, then, from the anus soft 4cm~8cm that inserts enemator slowly, open enemator, medicinal liquid is slowly poured in rectum, operating time is 2min~5min, and pouring into total amount is 100mL~150mL, and end of operation is closed enemator.Hold letterweight with left hand and live anus, the right hand is slowly extracted enemator.Patient gets right arm reclining, horizontal position, ventricumbent position, left lateral position, seat, semireclining position successively, adjusts position, the about 15min~20min of each position depending on the concrete state of an illness, last semipronation is had a rest, every day coloclysis once, retain a night, within 10 days, be 1 course for the treatment of, after 15 days, remission alleviates, continue again to use 3 the course for the treatment of pudendum have nice and cool sensation, lower abdomen is not swollen, moist phenomenon disappears, physical recovery is normal, does not recur so far.

Claims (10)

1. treat the Chinese medicinal enema of chronic prostatitis for one kind, it is characterized in that, in described Chinese medicinal enema, the parts by weight of various crude drug are: 10~20 parts of Herba Orobanchess, 10~20 parts, Poria, 10~20 parts of Semen Vaccariae, 10~20 parts of Fructus Schisandrae Chinensis, 10~20 parts of Herba Epimedii, 10~20 parts of Semen Cuscutae, 10~20 parts of Fructus Alpiniae Oxyphyllae, 10~20 parts of Fructus Corni, 10~20 parts of Herba Hedyotidis Diffusaes, 10~20 parts of Herba Taraxacis, 10~20 parts of Radix Polygoni Multiflori Preparata, 10~20 parts of Semen Plantaginiss, 10~20 parts of Radix Salviae Miltiorrhizaes, 10~20 parts of Cortex Phellodendris, 10~20 parts of Rhizoma Alismatis, 10~20 parts of Spica Prunellaes, 10~20 parts of Fructus Cnidiis, 10~20 parts of Herba Patriniae, 10~20 parts of Radix Scutellariaes, 10~20 parts of Radix Paeoniae Rubra, 10~20 parts of Rhizoma Smilacis Glabraes, 10~20 parts of Fructus Rubies, 10~20 parts of Cortex Moutans, 10~20 parts of Caulis Spatholobis.
2. treat according to claim 1 the Chinese medicinal enema of chronic prostatitis, it is characterized in that, in described Chinese medicinal enema, the parts by weight of various crude drug are: 10~15 parts of Herba Orobanchess, 10~15 parts, Poria, 10~15 parts of Semen Vaccariae, 10~15 parts of Fructus Schisandrae Chinensis, 10~15 parts of Herba Epimedii, 10~15 parts of Semen Cuscutae, 10~15 parts of Fructus Alpiniae Oxyphyllae, 10~15 parts of Fructus Corni, 10~15 parts of Herba Hedyotidis Diffusaes, 10~15 parts of Herba Taraxacis, 10~15 parts of Radix Polygoni Multiflori Preparata, 10~15 parts of Semen Plantaginiss, 10~20 parts of Radix Salviae Miltiorrhizaes, 10~20 parts of Cortex Phellodendris, 10~20 parts of Rhizoma Alismatis, 10~20 parts of Spica Prunellaes, 10~20 parts of Fructus Cnidiis, 10~20 parts of Herba Patriniae, 10~20 parts of Radix Scutellariaes, 10~20 parts of Radix Paeoniae Rubra, 10~20 parts of Rhizoma Smilacis Glabraes, 10~20 parts of Fructus Rubies, 10~20 parts of Cortex Moutans, 10~20 parts of Caulis Spatholobis.
3. treat according to claim 1 the Chinese medicinal enema of chronic prostatitis, it is characterized in that, in described Chinese medicinal enema, the parts by weight of various crude drug are: 10~20 parts of Herba Orobanchess, 10~20 parts, Poria, 10~20 parts of Semen Vaccariae, 10~20 parts of Fructus Schisandrae Chinensis, 10~20 parts of Herba Epimedii, 10~20 parts of Semen Cuscutae, 10~20 parts of Fructus Alpiniae Oxyphyllae, 10~20 parts of Fructus Corni, 10~20 parts of Herba Hedyotidis Diffusaes, 10~20 parts of Herba Taraxacis, 10~20 parts of Radix Polygoni Multiflori Preparata, 10~20 parts of Semen Plantaginiss, 10~15 parts of Radix Salviae Miltiorrhizaes, 10~15 parts of Cortex Phellodendris, 10~15 parts of Rhizoma Alismatis, 10~15 parts of Spica Prunellaes, 10~15 parts of Fructus Cnidiis, 10~15 parts of Herba Patriniae, 10~15 parts of Radix Scutellariaes, 10~15 parts of Radix Paeoniae Rubra, 10~15 parts of Rhizoma Smilacis Glabraes, 10~15 parts of Fructus Rubies, 10~15 parts of Cortex Moutans, 10~15 parts of Caulis Spatholobis.
4. a preparation method for the treatment of the Chinese medicinal enema of chronic prostatitis as described in any one in claim 1~3, is characterized in that, the preparation process of described enema comprises:
A. described crude drug is mixed, chopping, sieves, and soaks;
B. the crude drug of immersion being added to alcohol heating reflux extracts 2 times;
C. get again the medicinal residues after above-mentioned ethanol extraction, the heating and refluxing extraction that adds water 2 times;
D. above-mentioned two kinds of extracting solution are merged to decompression recycling ethanol disinfectant preparation.
5. treat according to claim 4 the preparation method of the Chinese medicinal enema of chronic prostatitis, it is characterized in that, in described step a, chopping after first described crude drug being mixed, XianCheng's coarse powder, more further pulverize, cross 120 mesh sieves, the fine powder amount that enable pass is crossed 120 mesh sieves is reaching 30%, collects that to obtain fine powder by the fine powder of 120 mesh sieves for subsequent use, and unsifted coarse granule is placed on and in ethanol, soaks 8-12 hour.
6. the preparation method for the treatment of according to claim 4 the Chinese medicinal enema of chronic prostatitis, is characterized in that, in described step b, by soaked crude drug coarse granule heating and refluxing extraction 2 times, each 1~2 hour, 2 extracting solution is merged and is left standstill.
7. the preparation method for the treatment of according to claim 4 the Chinese medicinal enema of chronic prostatitis, is characterized in that, in described step c, by add water heating and refluxing extraction 2 times of the medicinal residues after above-mentioned ethanol extraction, each 1~2 hour, 2 extracting solution is merged and is left standstill.
8. treat according to claim 4 the preparation method of the Chinese medicinal enema of chronic prostatitis, it is characterized in that, in described steps d, above-mentioned two kinds of extracting solution are merged, 1.35 filtrate when concentrating under reduced pressure relative density is 80 DEG C, reclaim ethanol, gained filtrate is adjusted to proportion to 1.06, paste materials reduces pressure to obtain, with ultraviolet-ray sterilizing, become enema.
9. a preparation method for the treatment of the Chinese medicinal enema of chronic prostatitis as described in any one in claim 1~3, is characterized in that, its preparation process comprises:
A, get crude drug and put into ethanol and soak, heat is extracted 2 times, becomes paste, is component 1;
B, medicinal residues extracting in water 2 times, thickening filtration is paste, is component 2;
C, above-mentioned two kinds of pastes are merged into enema.
10. the preparation method for the treatment of according to claim 9 the Chinese medicinal enema of chronic prostatitis, is characterized in that, in described step a, get in the ethanol that raw material adds 5-10 doubly to measure and soak 1-2 hour, heating extraction 2 times, each 1-2 hour, get supernatant, merge extractive liquid,, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, heating is concentrated into paste, and stand for standby use, becomes component 1; In described step b, the medicinal residues that ethanol extraction is crossed are put into 10 times of water gagings, heating and refluxing extraction 2 times, each extraction time is 1~2 hour, and 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, heating is concentrated into paste, and stand for standby use, becomes component 2; In described step c, above-mentioned two kinds of component paste concentrated solutions are merged, then use ultraviolet, disinfection, becomes enema.
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