CN103933509A - Medicine for treating saprolegniasis of freshwater fish and preparation method of medicine - Google Patents

Medicine for treating saprolegniasis of freshwater fish and preparation method of medicine Download PDF

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CN103933509A
CN103933509A CN201410129289.7A CN201410129289A CN103933509A CN 103933509 A CN103933509 A CN 103933509A CN 201410129289 A CN201410129289 A CN 201410129289A CN 103933509 A CN103933509 A CN 103933509A
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radix
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herba
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CN103933509B (en
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李淑翠
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Anhui Rong Xin Biological Technology Co Ltd
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Abstract

The invention discloses a medicine for treating saprolegniasis of freshwater fish and preparation method of the medicine. The medicine comprises the following raw medicinal materials: wild chrysanthemum, perilla stem, radix sileris, angelica root, centipeda minima, tamarix chinensis, ligusticum sinense oliver, Chinese pulsatilla root, Chinese lobelia, zaocys dhumnade, clematis root, berba aristolochiae mollissimae, lycopodium clavatum, dried ginger, pepper, dried orange peel, dutchmanspipe root, rhizoma nardostachyos, hawthorn, fevervine, ferula asafetida, bighead atractylodes rhizome, white hyacinth bean, acanthopanax, gynostemma, clinopodium herb, hyacinth bean coat, radix scrophulariae, vitex leaf, crotalaria leaf and silkworm shell. The medicine of the invention has the beneficial effects in mainly tonifying qi and helping digestion, detoxifying and removing sore by utilizing traditional Chinese veterinarian theory. The medicine has the advantages of good curative effect for treating saprolegniasis of freshwater fish, high safety and no toxic side effect.

Description

Be used for the treatment of medicine of fresh-water fishes fish molds and preparation method thereof
 
Technical field
The present invention relates to a kind of medicine of preventing and treating aquatic animal disease, particularly a kind of medicine that is used for the treatment of fresh-water fishes fish molds and preparation method thereof.
 
Background technology
Fish fish molds often infects body surface wounded tissue and dead ovum, form canescence as byssaceous covering, claim again to cover cotton disease or the cotton disease of water, claim again dermatomycosis or white defect, it is one of mycosis of aquatic Fish, the pathogen that causes this disease is having been found that kind more than ten up till now, and wherein modal is fish molds and continuous mould.This disease is to be caused by fungi autoeciousness fish body surface, is mainly Saprolegnia and the Achyla of Eumycota Mastigomycotina Phycomycetes Saprolegniales Saprolegniaceae.Water mo(u)ld is extensively stored in fresh water or brackish water waters and slowly drained soil all over the world, saprophytic on dead Organic substance, for a kind of mycete of being everlasting, mainly contain Saprolegniales, Peronosporales and Leptomitales etc., the most common with water mo(u)ld again, the most applicable growth in the time of 10 ~ 15 DEG C, the trip sporogenesis power in each when more than 25 DEG C weakens, more not easy infection, almost all can occur in Squaliobarbus ourriculus the whole year.
The generation of fish molds is mainly dyed because of the urgent secondary sexuality causing, a fish impact because of crowded, mobile or other poor environment factors, cause body surface organization injured, fish molds trip spore in water waits for an opportunity to adhere to, and on slough, starting to germinate forms mycelia, and mycelia is except parasitizing slough, still near can stretch invading normal structure, secretion zymigen decomposes surrounding tissue, more runs through corium and gos deep into muscle, makes skin and muscular death disintegrate.The mycelia on top layer stretches out, and forms as byssaceous covering, and forms Sporangium in end, emits trip spore in water, propagates everywhere via water.
Symptom is by the following aspects: 1, infection site forms canescence flocculence covering; 2, the diseased region initial stage rounded, stage is irregular speckle, when serious, skin injury muscle is exposed; 3, gill tissue also can be invaded and be infected, and causes death.
At present, prevention of water mildew method is by following method: (1) morbidity is 0.04% Sal and 0.04% sodium bicarbonate mixture full pool spilling head for fishpond; (2) injured parent fish can be smeared affected part with 4% sulphur wine; (3) fish roe can embathe 2-3 minute with 4% formalin; (4) in aquarium, water temperature is raised to 30 degree (not being suitable for cold water fish), adds 1% salt (not salt adding of the Fish of salt tolerant), within day, changes the water of three point one.But the prolonged application Western medicine of feeding, when easily producing drug resistance, also can increase the drug residue in Fish, especially the health of edible this type of fish is had a negative impact etc.The medicine for the treatment of fish molds has following several: 1, formalin, and 100 ~ 250ppm, stream is bathed 1 hour; 2, Sal, 1 ~ 1.5%, 20 ~ 30 minutes, purified salt, also could with rough salt; 3, malachite green oxalate, edible fish forbidding; 4, while there is bacillary mixed infection, also need to coordinate antibiotic therapy.Although Western medicine has certain curative effect to mycosis, not ideal, and prolonged application western medicine, easily produce drug resistance, but also can increase the drug residue in Fish, especially the health of edible this type of fish is had a negative impact etc.
Traditional Chinese medical science control Fish fish molds, is particular about prevention of diseae, control combination, not only has the effect of Western medicine, also has the advantage that Western medicine does not have.The traditional Chinese medical science adopts natural Chinese medicines material, controls by dialectical opinion, and symptomatic treatment, drug residue free, pollution-free, and be applicable to large-area application.
 
Summary of the invention
Technical problem to be solved by this invention is, a kind of medicine for the treatment of fresh-water fishes fish molds and preparation method thereof is provided, this Chinese medicine taking QI invigorating help digestion, detoxification and sores is as main, that treatment fresh-water fishes fish molds has is rapid-action, determined curative effect, the safe and advantage that has no side effect.
In order to solve the problems of the technologies described above, the invention provides a kind of medicine that is used for the treatment of fresh-water fishes fish molds, wherein, comprise following raw medicinal material: Flos Chrysanthemi Indici, Caulis Perillae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Centipedae, Ramulus et Folium Tamaricis, Rhizoma Ligustici, the Radix Pulsatillae, Herba Lobeliae Chinensis, Zaocys, Radix Clematidis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Rhizoma Zingiberis, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae, Radix Aristolochiae, Radix Et Rhizoma Nardostachyos, Fructus Crataegi, fevervine, Resina Ferulae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Radix Et Caulis Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, Herba clinopodii confinis (Herba Clinopodii Gracilis), Testa dolichoris, Radix Scrophulariae, Folium Viticis Negundo, Caulis et Folium Crotalariae Assamicae and Crusta Bombycis ovum.
In described medicine, the parts by weight of each raw medicinal material are preferably: Flos Chrysanthemi Indici 10-25 weight portion, Caulis Perillae 5-15 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Angelicae Dahuricae 8-17 weight portion, Herba Centipedae 10-25 weight portion, Ramulus et Folium Tamaricis 8-15 weight portion, Rhizoma Ligustici 10-16 weight portion, Radix Pulsatillae 10-20 weight portion, Herba Lobeliae Chinensis 5-15 weight portion, Zaocys 8-20 weight portion, Radix Clematidis 5-10 weight portion, Herba Aristolochiae Mollissimae 8-15 weight portion, Herba Lycopodii 10-20 weight portion, Rhizoma Zingiberis 10-25 weight portion, Pericarpium Zanthoxyli 8-15 weight portion, Pericarpium Citri Reticulatae 10-20 weight portion, Radix Aristolochiae 5-10 weight portion, Radix Et Rhizoma Nardostachyos 15-25 weight portion, Fructus Crataegi 10-25 weight portion, fevervine 8-17 weight portion, Resina Ferulae 8-15 weight portion, Radix Astragali 10-20 weight portion, Rhizoma Atractylodis Macrocephalae 10-20 weight portion, Semen Lablab Album 10-15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15-20 weight portion, Herb Gynostemmae Pentaphylli 5-15 weight portion, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15-25 weight portion, Testa dolichoris 10-25 weight portion, Radix Scrophulariae 10-25 weight portion, Folium Viticis Negundo 15-20 weight portion, Caulis et Folium Crotalariae Assamicae 8-17 weight portion and Crusta Bombycis ovum 10-20 weight portion.
In described medicine, the parts by weight of each raw medicinal material can also be preferably: Flos Chrysanthemi Indici 17 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 15 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 17 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 13 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 10 weight portions, Zaocys 14 weight portions, Radix Clematidis 7 weight portions, Herba Aristolochiae Mollissimae 11 weight portions, Herba Lycopodii 15 weight portions, Rhizoma Zingiberis 17 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 15 weight portions, Radix Aristolochiae 7 weight portions, Radix Et Rhizoma Nardostachyos 20 weight portions, Fructus Crataegi 17 weight portions, fevervine 12 weight portions, Resina Ferulae 12 weight portions, the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 17 weight portions, Herb Gynostemmae Pentaphylli 10 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 20 weight portions, Testa dolichoris 17 weight portions, Radix Scrophulariae 18 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 12 weight portions and Crusta Bombycis ovum 15 weight portions.
In described medicine, the parts by weight of each raw medicinal material can be preferably again: Flos Chrysanthemi Indici 10 weight portions, Caulis Perillae 15 weight portions, Radix Saposhnikoviae 20 weight portions, the Radix Angelicae Dahuricae 17 weight portions, Herba Centipedae 25 weight portions, Ramulus et Folium Tamaricis 8 weight portions, Rhizoma Ligustici 16 weight portions, the Radix Pulsatillae 20 weight portions, Herba Lobeliae Chinensis 15 weight portions, Zaocys 8 weight portions, Radix Clematidis 10 weight portions, Herba Aristolochiae Mollissimae 8 weight portions, Herba Lycopodii 20 weight portions, Rhizoma Zingiberis 25 weight portions, Pericarpium Zanthoxyli 8 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Radix Aristolochiae 5 weight portions, Radix Et Rhizoma Nardostachyos 15 weight portions, Fructus Crataegi 25 weight portions, fevervine 17 weight portions, Resina Ferulae 15 weight portions, the Radix Astragali 10 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Semen Lablab Album 15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 20 weight portions, Herb Gynostemmae Pentaphylli 15 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 25 weight portions, Testa dolichoris 10 weight portions, Radix Scrophulariae 25 weight portions, Folium Viticis Negundo 20 weight portions, Caulis et Folium Crotalariae Assamicae 17 weight portions and Crusta Bombycis ovum 10 weight portions.
In described medicine, the parts by weight of each raw medicinal material can be preferably again: Flos Chrysanthemi Indici 25 weight portions, Caulis Perillae 15 weight portions, Radix Saposhnikoviae 10 weight portions, the Radix Angelicae Dahuricae 8 weight portions, Herba Centipedae 10 weight portions, Ramulus et Folium Tamaricis 15 weight portions, Rhizoma Ligustici 10 weight portions, the Radix Pulsatillae 10 weight portions, Herba Lobeliae Chinensis 5 weight portions, Zaocys 20 weight portions, Radix Clematidis 5 weight portions, Herba Aristolochiae Mollissimae 15 weight portions, Herba Lycopodii 10 weight portions, Rhizoma Zingiberis 10 weight portions, Pericarpium Zanthoxyli 15 weight portions, Pericarpium Citri Reticulatae 10 weight portions, Radix Aristolochiae 10 weight portions, Radix Et Rhizoma Nardostachyos 25 weight portions, Fructus Crataegi 10 weight portions, fevervine 8 weight portions, Resina Ferulae 8 weight portions, the Radix Astragali 20 weight portions, the Rhizoma Atractylodis Macrocephalae 10 weight portions, Semen Lablab Album 10 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15 weight portions, Herb Gynostemmae Pentaphylli 5 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15 weight portions, Testa dolichoris 10 weight portions, Radix Scrophulariae 10 weight portions, Folium Viticis Negundo 15 weight portions, Caulis et Folium Crotalariae Assamicae 8 weight portions and Crusta Bombycis ovum 10 weight portions.
Described medicine also comprises Herba Galii Teneri, Semen vignae sinensis, Massa Medicata Fermentata, Radix Bupleuri and Herba polygoni senticosi.
In described medicine, the parts by weight of each raw medicinal material are preferably: Flos Chrysanthemi Indici 10-25 weight portion, Caulis Perillae 5-15 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Angelicae Dahuricae 8-17 weight portion, Herba Centipedae 10-25 weight portion, Ramulus et Folium Tamaricis 8-15 weight portion, Rhizoma Ligustici 10-16 weight portion, Radix Pulsatillae 10-20 weight portion, Herba Lobeliae Chinensis 5-15 weight portion, Zaocys 8-20 weight portion, Radix Clematidis 5-10 weight portion, Herba Aristolochiae Mollissimae 8-15 weight portion, Herba Lycopodii 10-20 weight portion, Rhizoma Zingiberis 10-25 weight portion, Pericarpium Zanthoxyli 8-15 weight portion, Pericarpium Citri Reticulatae 10-20 weight portion, Radix Aristolochiae 5-10 weight portion, Radix Et Rhizoma Nardostachyos 15-25 weight portion, Fructus Crataegi 10-25 weight portion, fevervine 8-17 weight portion, Resina Ferulae 8-15 weight portion, Radix Astragali 10-20 weight portion, Rhizoma Atractylodis Macrocephalae 10-20 weight portion, Semen Lablab Album 10-15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15-20 weight portion, Herb Gynostemmae Pentaphylli 5-15 weight portion, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15-25 weight portion, Testa dolichoris 10-25 weight portion, Radix Scrophulariae 10-25 weight portion, Folium Viticis Negundo 15-20 weight portion, Caulis et Folium Crotalariae Assamicae 8-17 weight portion, Crusta Bombycis ovum 10-20 weight portion, Herba Galii Teneri 13-20 weight portion, Semen vignae sinensis 15-20 weight portion, Massa Medicata Fermentata 15-20 weight portion, Radix Bupleuri 15-25 weight portion and Herba polygoni senticosi 10-20 weight portion.
In described medicine, the parts by weight of each raw medicinal material can also be preferably: Flos Chrysanthemi Indici 15 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 12 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 16 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 12 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 11 weight portions, Zaocys 11 weight portions, Radix Clematidis 6 weight portions, Herba Aristolochiae Mollissimae 12 weight portions, Herba Lycopodii 16 weight portions, Rhizoma Zingiberis 15 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 12 weight portions, Radix Aristolochiae 6 weight portions, Radix Et Rhizoma Nardostachyos 18 weight portions, Fructus Crataegi 21 weight portions, fevervine 11 weight portions, Resina Ferulae 9 weight portions, the Radix Astragali 18 weight portions, the Rhizoma Atractylodis Macrocephalae 14 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18 weight portions, Herb Gynostemmae Pentaphylli 8 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 21 weight portions, Testa dolichoris 12 weight portions, Radix Scrophulariae 15 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 11 weight portions, Crusta Bombycis ovum 15 weight portions, Herba Galii Teneri 15 weight portions, Semen vignae sinensis 16 weight portions, Massa Medicata Fermentata 17 weight portions, Radix Bupleuri 19 weight portions and Herba polygoni senticosi 15 weight portions.
In order better to realize foregoing invention object, the present invention also provides a kind of preparation method of the medicine that is used for the treatment of fresh-water fishes fish molds, described preparation method comprises the following steps: described raw medicinal material is mixed by proportioning, chopping, put into acid and alkali-resistance infusion kettle, at room temperature, flood 15-22 days together with being the above ethanol of 90 degree with alcoholic degree, the liquid having flooded and medicinal residues are carried out to squeeze and filter, after separation, get filtrate; The heating of described filtrate is concentrated into pasty state, puts into drying in oven, cooling after with grind to form fine-powdered, obtain drug powder.
The using method that is used for the treatment of the medicine of fresh-water fishes fish molds is: described medicine is processed into after powder to feeding after directly mixing with fish meal, the 2-6% that the addition of medicine is fish meal.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: medicine of the present invention, utilize China tradition Chinese veterinarian theory, taking QI invigorating help digestion, detoxification and sores is as main, treatment fresh-water fishes fish molds has good effect, the safe and advantage that has no side effect.
 
Detailed description of the invention
China's Chinese herbal medicine resource vast in territory is very abundant, aspect development Chinese medicine, there are being huge potentiality, a large amount of production practices and scientific research have also confirmed that Chinese herbal medicine has many nutritional labelings and bioactive substance, as alkaloid, polysaccharide, volatile oil, organic acid etc., have the dual function of the property of medicine and trophism concurrently, both preventable disease, can improve again fertility performance; Not only direct bactericidal, and can regulate the immune function of body, there is non-specific antibacterial action.Therefore abandon chemical classes medicine, use the relieved Chinese medicine of safety, making food reach the delicious effect of safety is our consistent pursuit; Advantage that the more important thing is Chinese medicine uniqueness is to have pure natural property, from nature animal, plant and mineral, and its natural structure and activity are kept, life-time service and drug residue free, without Drug resistance with have no side effect, it is good Green medicament, also catered to consumers in general and the culturist pursuit to green non-pollution no drug residue product, in letting animals feed, seemed more meaningful so do medicine with Chinese herbal medicine.
The invention provides a kind of medicine that is used for the treatment of fresh-water fishes fish molds, wherein, comprise following raw medicinal material: Flos Chrysanthemi Indici, Caulis Perillae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Centipedae, Ramulus et Folium Tamaricis, Rhizoma Ligustici, the Radix Pulsatillae, Herba Lobeliae Chinensis, Zaocys, Radix Clematidis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Rhizoma Zingiberis, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae, Radix Aristolochiae, Radix Et Rhizoma Nardostachyos, Fructus Crataegi, fevervine, Resina Ferulae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Radix Et Caulis Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, Herba clinopodii confinis (Herba Clinopodii Gracilis), Testa dolichoris, Radix Scrophulariae, Folium Viticis Negundo, Caulis et Folium Crotalariae Assamicae and Crusta Bombycis ovum; Preferably, medicine also comprises Herba Galii Teneri, Semen vignae sinensis, Massa Medicata Fermentata, Radix Bupleuri and Herba polygoni senticosi.
Wherein, the pharmacology of above-mentioned raw materials medical material is as follows:
Flos Chrysanthemi Indici: cold nature, bitter in the mouth, pungent." book on Chinese herbal medicine converges and says ": " removing blood stasis is soothing the liver, separates the loose poison of furuncle.Stagnated blood in housewife people's abdomen, the red furuncle of the capable fire-toxin of Xie Tian.Wash skin ulcer scabies, can remove again wind parasite killing." function heat-clearing and toxic substances removing, detumescence.To staphylococcus aureus, diphtheria corynebacterium, streptococcus, bacillus pyocyaneus, puncture Shigella, influenza virus, all there is inhibitory action.To furuncle, carbuncle, erysipelas, eczema, dermatitis, anemopyretic cold, laryngopharynx swelling and pain, hypertension etc. have good curative effect.
Caulis Perillae: pungent, temperature.Return lung, spleen channel.Can relieving the exterior syndrome by diaphoresis, regulating the flow of QI to ease the stomach, solving toxin of fish and crab.For anemofrigid cold, headache, cough, distension and fullness of the chest and abdomen, fish Eriocheir sinensis is poisoning.Folium Perillae acrid in the mouth warm in nature, have induce sweat, cold expelling, the effect of regulating the flow of vital energy and seeking.Be applicable to the diseases such as cold, fever with aversion to cold, cough, asthma, distension and fullness of the chest and abdomen.Folium Perillae Herb all has very high nutritive value, and it has low sugar, high fiber, high carotene, high mineral element etc.In volatile oil, contain perillaldehyde, perilla alcohol, menthone, menthol, eugenol, ergomaketon etc.Defying age element SOD in every milligram of Folium Perillae content up to 106.2 micrograms.Find after deliberation, the each position of Folium Perillae evenly has good antitumaous effect, especially stronger with the effect in blade, oleanolic acid is wherein a kind of very strong natural anti-cancer agent, there is the effect of prophylaxis of tumours, there is again the effect of antiinflammatory, calmness, heart tonifying, diuresis, enhancing immunity, blood fat reducing and resistance growth of cancer cells.Folium Perillae can diaphoresis cold expelling to separate pathogenic factor in the exterior, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, resolving depression preventing or arresting vomiting, therefore wind and cold table disease is doublely seen to symptoms of emesis uncomfortable in chest, use this product, be very suitable; Or have the stagnation of QI not smooth symptom without table disease, also can be used for a surname logical.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature; Enter urinary bladder channel, lung meridian, spleen channel, Liver Channel." Japan hanako materia medica ": " wind as controlling 36, all labor of man are bad, invigorating middle warmer benefit god, blepharitis marginalis, arresting lacrimation and paralysis are slow, tonneau the five internal organs GUAN-pulse, five kinds of strain and seven kinds of impairment, thin damage night sweat, vexed body weight, energy tranquilizing the mind, even gaseous pulse." " Changsha medicine solution ": " and the network of passing through, by wet excessive, gets round by bribery, the pain that relieves the pain, and relaxing muscles and tendons arteries and veins, stretches anxious twinly, and the podomere of living, plays paralysis, holds back spontaneous perspiration, night sweat, breaks, metrorrhagia." function expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.For affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, joint is ached, stomachache is had loose bowels, discharging fresh blood stool, tetanus, rubella pruritus, skin infection from the beginning of.Deficiency of YIN-blood, calentura wind symptom person should not use, and blood deficiency convulsion urgency or headache be not because ailment said due to cold or exposure person avoids clothes.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature; Return lung, stomach, large intestine channel." Japan hanako materia medica ": " control conjunctival congestion bulbar conjunctiva polyp, and tire patching leakage landing, broken stagnated blood, mends fresh blood, acute mastitis, carbuncle on the back, scrofula, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, and evacuation of pus, scabies, desolation, pain relieving granulation promoting, go face Shao-defect scar." Compendium of Material Medica: " and control nasal sinusitis, epistaxis, toothache, supraorbital bone pain, large intestine constipation due to pathogenic wind, married woman's blood dizziness due to wind pathogen fortune, bleeding urine, regurgitation of food from the stomach is told food; Solution arsenic poison, snakebite, cutter arrow incised wound." function expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidifying are sensible, detumescence and apocenosis.Cure mainly anemofrigid cold, headache, supraorbital bone pain, toothache, eye itching lacrimation, nasal obstruction, nasal sinusitis, wet chronic diarrhea, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, pruritus scabies, the venom contained.Can improve microcirculation in human body, promote skin metabolism, and the water soluble ingredient of the Radix Angelicae Dahuricae have vasoconstrictor effects, the Coumarins composition byak-angelicin of the Radix Angelicae Dahuricae has dilating effect to coronary vasodilator.
Herba Centipedae: dispersing wind-cold, clearing the nasal passage, cough-relieving, removing toxic substances.Compendium of Material Medica: " loose conjunctival congestion is swollen for removing toxic substances, improving eyesight, nebula, deafness, and headache olic acid, controls Tan Nve Snore clam, has a stuffy nose obstructed, and plug breath is from falling, and loose skin ulcer is swollen again." this savors decoct 25-50% that tubercule bacillus is had to inhibitory action.This product volatile oil and ethanol extract part have cough-relieving, eliminate the phlegm, antiasthmatic effect.Brevelin shows has inhibitory action to rat Walker sarcoma, and the derivant of some Helenalin also shows active anticancer.The hot water extract of Herba Centipedae provides significant antiallergic activity through passive cutaneous anaphylaxis test performance.Methanol soluble fraction by the chloroform extract of Herba Centipedae separates Arnicolidec, the 6-O-Senecioylplenolin, Aurantiamideacetate and three flavone compound Quercetin-3 that obtain, 3 dimethyl esters, Quercetin 3-methyl ester and apigenin have all shown stronger antiallergic activity.
Ramulus et Folium Tamaricis: sweet in the mouth, pungent, property are flat; Return lung meridian, stomach warp, heart channel.Essentials of Matea Medica: " control acute diseases such as cholera and sunstroke rash and do not go out, breathe heavily the vexed unrest of coughing." function dispelling wind, induce sweat, rash, removing toxic substances.Cure mainly anemopyretic cold, measles from the beginning of, rash goes out not saturating, rheumatic arthralgia, skin pruritus.Control measles thoroughly difficult, rubella itching over the body, flu, cough with asthma, rheumatic ostalgia.Ramulus et Folium Tamaricis decoct is injected 5g/kg to mouse peritoneal, has obvious antitussive action (ammonia spraying draws the method for coughing), but without phlegm-dispelling functions (the phenol red method of mice).In vitro tests, Ramulus et Folium Tamaricis decoct all has inhibitory action to streptococcus pneumoniae, alpha streptococcus, Staphylococcus albus and hemophilus influenza.
Rhizoma Ligustici: pungent, temperature.Return urinary bladder channel." herbal classic ": " housewife people's hernia abdominal mass, cloudy invasion by pathogenic cold swells and ache, anxious in abdomen, except wind headache, longue skin." dispel the wind, cold expelling, dehumidifying, pain relieving.For anemofrigid cold, top, mountain peak pain, rheumatic arthralgia.Rhizoma Ligustici is containing volatile oil, its Main Ingredients and Appearance be the 3-fourth moon too, the cnidium monnieri moon too lactone, distant Rhizoma Ligustici root containing volatile oil 1.5%.Rhizoma Ligustici neutral oil has calmness, analgesia, antipyretic and antiinflammatory action, and can suppress intestinal and uterine smooth muscle, and keto consumpting speed can also obviously slow down.Alcohol extraction has hypotensive effect, and common pathogenic dermatophytosis is had to antibacterial action.
The Radix Pulsatillae: bitter in the mouth, cold in nature; Return stomach warp, large intestine channel." herbal classic is met former ": " Radix Pulsatillae, " herbal classic " says bitter temperature person, the mistake of making private copy of is also.It controls the diseases such as the mad easy cold and heat of pyrexial malaria, all few sun, the fixed disease of positive bright pathogenic heat, and the loose hematocele of knot goes and only suffers from abdominal pain." not Lu " be epistaxis only, and great scape stops fulminant dysentery, is also that pyretic toxicity enters the time that blood trouble is divided." " property of medicine opinion ": " only stomachache and also fulminant dysentery, control toothache, tumor scrofula under major event.Main hundred pain all over the joints." can heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, removing dampness and killing parasites, for pyretic toxicity dysentery, epistaxis, internal hemorrhoid with bleeding, leukorrhagia, pudendal pruritus, carbuncle skin ulcer, scrofula.Radix Pulsatillae infusion can extend the survival date of suffering from influenza virus PR8 white mice, and its pulmonary lesion is also had slightly and alleviated." Bencao Jingshu ": " dysentery insufficiency of stomach is not thought food, and diarrhea with entirely indigested food do not change, have loose bowels due to deficiency and coldness cold-damp, and not because noxious dampness person avoids it.”
Herba Lobeliae Chinensis: sweet in the mouth; Property is put down.GUIXIN warp, lung meridian, small intestine meridian." Luchuan book on Chinese herbal medicine ": " detoxicating, relieving inflammation, diuresis, hemostasia and promoting granulation.Control ascites, infantile convulsion, two unilateral tonsillitis, dermatitis rhus, traumatic hemorrhage, skin scabies, Serpentis honeybee scorpion wound." function heat-clearing and toxic substances removing, inducing diuresis to remove edema.Cure mainly in venom carbuncle furuncle, tonsillitis, warm rash, tinea pedis, traumatic injury, jaundice due to damp-heat, appendicitis, enteritis, nephritis, cirrhotic ascites and kinds cancer.
Zaocys: sweet in the mouth, property is flat; Return liver, spleen channel.There is wind-damp dispelling, the meridian dredging, relieving spasm by subduing liver-wind, effect of anti-itch detoxification.Cure mainly rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, infantile convulsion, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.Snake blood clear (comprising Zaocys, Flos pini Serpentis and Agkistrodon serum) all has significant protective effect to the injection of white mice time full lethal dose or two times of lethal dose agkistrodon acutus venom; To the white mice of injection agkistrodon acutus venom give snake blood clear after, can make its clotting time normal; Every milliliter of Agkistrodon serum can deactivation agkistrodon acutus venom 5 milligrams; Inject that within latter 10 minutes, to inject snake blood clear again, white mice is also had to protective effect.
Radix Clematidis: pungent, salty, temperature.Return urinary bladder channel." Kaibao Bencao ": " main all wind, Xuan Tongwu hides, and goes abdomen interior cold stagnant, and septum cordis expectorant water is long-pending for a long time, lump in the abdomen Xuan tinea air parcel, bladder place pus aversion to water, the cold pain of waist knee joint and treatment injured." " herbal classic is met former ": " varioliform exanthema poison is stopped up in upper and can not be assigned, and under waist, shin knee joint rises and fills with slow person, under being, draws." there is expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, effect of the loose hypochondriac lump, cures mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, the cards such as all a fishbone or other bone caught in the throat pharynxs.
Herba Aristolochiae Mollissimae: bitter in the mouth is flat.Return Liver Channel.Wind-damp dispelling, the meridian dredging, pain relieving.For rheumatic arthralgia, numb limbs and tense tendons, muscles and bones contracture, traumatic injury pain.
Herba Lycopodii: bitter, pungent, warm, enter Liver Channel.Supplement to the Herbal: " owner suffers from migratory arthralgia for a long time, and foot knee joint pain is cold, munbness, and strength is weak." " Hunan medicine will ": " relaxing muscles and tendons to promote blood circulation, invigorating qi and dredging collateral.Control lumbago, arthralgia, amenorrhea." expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.External is controlled osteopatia sprain and is swollen and ache.This product water logging agent has cooling effect to experimental rabbit.30 mgs/kg of intravenous injection lycopodines can make anesthetized cat, Sanguis Leporis seu oryctolagi press rapid drawdown, and toxic dose can increase animal breath amplitude and reduce frequency.External extremely sensitive to shigella flexneri, sonne bacillus, to dysentery bacterium medium sensitivity.Lycopodine has potentiation to frog contractile force.Isolated rat, Cavia porcellus, Intestine in Rabbits smooth muscle are had to excitation.There is to excitation in rabbit, rat and Cavia porcellus uterus.
Rhizoma Zingiberis: mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower." herbal classic ": Your Majesty's gas cough with dyspnea, stagnation of QI sore throat is told suction, sharp joint, invigorating the spleen and replenishing QI." not Lu ": main pained, side of body wind, hypochondriac pain, warm muscle, promotes blood circulation, only tired, perspire.Main warming middle-JIAO, benefitting liver and lung gas, trusted subordinate's cold and heat, cold disease, cramp caused by acute vomiting and diarrhea, headache, lumbago, only saliva, cough ， Bi Weng; Can have an abortion, hard joint, promoting blood circulation, reason is dredged not enough; A surname leads hundred medicines, and nothing institute is feared.3. " property of medicine opinion ": cure mainly nine types of precordial pain, kill three worms, main removing blood stasis, the tonneau moon closes, and controls weak foot, numbness, meciless, retention of placenta, except cough with dyspnea, stagnation of QI, gathers around numbness, and only cold air in abdomen, unbearably painful, main dysentery, nasal polyp.Herbicide wood poison.
Pericarpium Zanthoxyli: pungent, warm, return spleen, stomach, kidney channel.Compendium of Material Medica record: " the hard tooth of Pericarpium Zanthoxyli, black hair, improving eyesight, take for a long time, good color, resistance to old, increasing year, strong refreshing." can, except the stink smell of various meats, promote salivation, increase appetite, distend the blood vessels, thereby play the effect reducing blood pressure; Take pepper water and can remove parasite; There is effect of fragrant stomach invigorating, warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing removing toxic substances, antipruritic solution raw meat.Too much edible easy consumption intestinal moisture causes constipation, can raw tunica albuginea, spoiled after Pericarpium Zanthoxyli makes moist.When keeping, to be placed on dry place, guard against damp.A small amount of clothes that continue can promote relevant metabolic glandular development, and volume can promote the glandular development about reproduction.
Pericarpium Citri Reticulatae: nature and flavor hardship, pungent, temperature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm.Can be used for fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Therefore Pericarpium Citri Reticulatae has three major types effect, the one, lead cold-evil in the heart, two broken stagnant gas, three strengthening the spleen stomaches.This three greatly on, Main Function is row QI of the spleen and stomach.The main transmitting and distributing the fluids of taste, therefore QI of the spleen and stomach capablely can dry, spleen invigorating, reduce phlegm, therefore can say again, Pericarpium Citri Reticulatae temperature can be supported spleen, pungent can being amusing, bitter can spleen invigorating.Due to the main row QI of the spleen and stomach of Pericarpium Citri Reticulatae, taste are located in middle Jiao, and middle Jiao's gas is current, and the gas of three warmers is also sprung up thereupon.Three warmers are the organ in charge of water circulation, and current water liquid, accompanies with wetting phase; Again for hiding mansion outside mansion, the upper and heart, lung, lower and liver, kidney.So the effect of Pericarpium Citri Reticulatae can wide and all Zang Fu, spread all over whole body wet.Say from lung, pungent loose lung qi, hardship is let out lung qi, and temperatureization cold can be controlled abundant expectoration cough with asthma, and gas is stopped up food and is stopped; Say from the heart, pungent happy gas, hardship is let out heart-fire, and warm removing dampness is turbid, can control irritable feverish sensation in the chest, and the implication sound of vomiting is smelly; Say from liver, pungent loose stagnation of liver-QI, liver-fire falls in hardship, warming for eliminaring cold-damp, so its can treating the liver strongly fragrantly has heat, drink is stopped eating stagnant; Say from kidney, pungent profit kidney is dry, and it is wet that hardship is let out kidney, and gentle kidney qi, so it can control life fire deficiency, indigestion.Certainly, all explanations, all with wet relevant with spleen, so its property of medicine effect performance leeway is larger, all can be used in general activating QI to eliminate phlegm side.Anesthetized rabbit, cat, dog intravenous injection are had to hypotensive effect slowly, and its decompression principle is owing to directly acting on vascular smooth muscle.
Radix Aristolochiae: arduous, cold.Enter lung, stomach warp.Tang Materia Medica: " main gathering.All scorchingly hot swollen, snake venom, water rub into mudding it, days three, four; Treat furuncle enlargement effect." " vegetation is side just ": " delivers, except wind.The paralysis of (controlling) rheumatism, waist foot pain, traumatic injury." circulation of qi promoting, removing toxic substances, detumescence.Control chest and abdomen swelling and pain, acute filthy disease, enteritis dysentery, hypertension, hernia, Serpentis stings poison, carbuncle, furuncle, skin pruritus or wet rotten., Radix Aristolochiae (Radix Aristolochiae) crude preparation by using is to various animals, no matter intravenous injection or orally all can cause certain hypotensive effect, and general decoct effect is stronger.To anesthetized animal row vein, injection often causes rapid drawdown form, and intramuscular injection is slower, oral slower.Useful Radix Aristolochiae among the people is controlled stomachache person, uses clinically its crude preparation by using, side effect such as also causing nausea, vomit and be dizzy.The emetic action of Radix Aristolochiae causes mainly due to wherein contained ether soluble acidic composition, and Radix Aristolochiae crude preparation by using has sedation to mice.Chemoreceptor in spleen, the lower limb of refining extractum to rabbit isolated uterine and cat is all without very effect.In the time of heavy dose, there is the effect of some anti-fowl malaria and vitro inhibition dysentery bacterium.
Radix Et Rhizoma Nardostachyos: acrid in the mouth, sweet, warm in nature; Return spleen, stomach warp.Compendium of Material Medica: " Radix Et Rhizoma Nardostachyos, it is strongly fragrant that fragrance can be opened spleen, adds less in taste medicine the gas of being very amusing "." Japan hanako materia medica ": " control abdominal distnetion, the therapeutic method to keep the adverse QI flowing downwards." to have fragrance row loose for Radix Et Rhizoma Nardostachyos, warming spleen and stomach for dispelling cold, regulating QI to relieve pain, effect of the appetizing of being amusing.Cure mainly coldness and pain in the epigastrium distension, anorexia, chest pain, toothache, the tumbling down pain of injury, beriberi edema, cramp caused by acute vomiting and diarrhea.Jatamansi volatile oil has faint antibacterial, wind dispelling and spasmolysis, to skin, mucosa without local irritation.Jatamansi is to rabbit hemostasis, and rabbit performance is to the bradykinesia, sleepy, the loss of appetite that stimulate.Radix Et Rhizoma Nardostachyos alcohol extract has blood pressure lowering and antiulcer action.
Fructus Crataegi: modern study Fructus Crataegi, containing materials such as saccharide, protein, fat, vitamin C, carotene, starch, malic acid, citric acid, calcium and ferrum, has the effects such as blood fat reducing, blood pressure, heart tonifying and arrhythmia.Flavone compound vitexin in Fructus Crataegi, is the medicine that a kind of antitumaous effect is stronger, and Fructus Crataegi extract all has certain inhibitory action to cancerous cell tumor growth, propagation and infiltration metastasis.Fructus Crataegi, " herbal classic " cloud: sour in the mouth, air cooling, so see its can help digestion long-pending, clots absorbing blood, gas is non-cold.Having stagnates becomes dysentery, prolonged lochia, and holding in lunar part is after-pains.It is stagnant that Fructus Crataegi can enter taste removing food stagnancy, and loose stagnated blood, therefore in harness the river dysentery and puerpera's abdomen piece pain is also.On the whole its merit is longer than dissipating fluid-retention food, strengthening the spleen and stomach, row stagnation of QI, repercussive blood, therefore children's puerpera should polyphagia it." herbal classic " is mistaken for cold, therefore the use that has the skin ulcer of washing to itch.Can prevention and cure of cardiovascular disease, there is blood vessel dilating, increase coronary flow, improve heart vigor, stimulating central nervous system system, reduce blood pressure and cholesterol, vessel softening and diuresis and sedation; There is cardiotonic, helpful to senile heart disease; Energy appetite-stimulating indigestion-relieving, offsets meat stagnation effect better; There is effect of activating blood circulation to dissipate blood stasis, contribute to remove local congestion state, traumatic injury is had to auxiliary curative effect; There is to contraction in uterus, has the effect expediting the emergence of anemia of pregnant woman just before giving birth time, and can promote uterine involution in puerperal; The substance blocking-up such as contained flavonoid and vitamin C, carotene, reduce the generation of free radical, and the immunity of enhancing body, has anti-aging, anticancer effect; In Fructus Crataegi, having relievings asthma reduces phlegm, the composition of anti-bacteria, treatment abdominal pain diarrhea.
Fevervine: property is flat, sweet in the mouth, micro-hardship." the SHENGCAO property of medicine is standby to be wanted ": " its head is controlled new internal injury, and pot is carnivorous, and tonify deficiency kidney tonifying, except fire is enriched blood; Wash skin ulcer pain relieving, the loose poison of the heat that disappears.Its leaf is beaten rice with confectionery, dysentery relieving." " Zhiwu Mingshi Tukao ": " be wash, removing toxic substances, removes wind, heat clearing away, cold expelling.Apply innominate toxic swelling, and mend muscles and bones." expelling wind and activating blood circulation, analgesic antidotal, dyspepsia and intestinal stasis relieving, dehumidifying detumescence.Dispelling the wind and dampness pathogens pain, diarrhoea dysentery, dirty abdomen pain, deficiency of vital energy edema, dizzy lack of appetite, hepatosplenomegaly, scrofula, acute appendicitis, innominate toxic swelling, traumatic injury.Fevervine total alkaloids lumbar injection can suppress mice voluntary activity, extends pentobarbital sodium length of one's sleep, has certain sedation.Fevervine total alkaloids can suppress myenteron and shrink, and can antagonism myenteron contracture due to acetylcholine.Fevervine decoct has inhibitory action to external staphylococcus aureus and Fu Shigella flexneri, and extractum also has bacteriostasis to staphylococcus aureus and streptococcus pneumoniae.
Resina Ferulae: bitter in the mouth, pungent, warm in nature, return kidney, stomach warp, Tang Materia Medica: " master kills all small worms, the gas of deodorizing, and broken disease is long-pending, lower bad odor." " Japan hanako materia medica ": " controls biography corpse, broken disease addiction, and cold air, wards off temperature, treating malaria, the main cholera cardiac and abdominal pain of holding concurrently, kidney qi, warm miasma, imperial all gill fungus dish poison." there is removing food stagnancy, loose painful abdominal mass, effect of parasite killing, for meat stagnation, blood stasis lump in the abdomen, mass in abdomen, the cards such as abdominal pain due to worm stagnation.Resina Ferulae volatile oil aqueous emulsion can stop Anaphylactic mediator to discharge and mast cell degranulation, and can direct antagonism histamine and the contractile response of SRSA to airway smooth muscle.From root of Resina Ferulae or rhizome cut, the rubber resin of gained is Resina Ferulae, has special foul smell, bitter in the mouth and pungent; Can absorb from intestines and stomach, even if a large amount of (12 grams) are also without remarkable toxicity; Can be used as carminative (with 4%15～30 milliliters of coloclysis, simultaneously taking aperient), but in 3 days, should not use after intestinal surgery.Its volatile oil is discharged from lung, therefore at bronchitis, pertussis or asthmatic patient, can be used as stimulant expectorant.
The Radix Astragali: sweet, tepor; Return lung, spleen, liver, kidney channel.Essentials of Matea Medica: " lossless can sending out, has antiperspirant to stop for the Radix Astragali, life consolidating superficial resistance; Process with invigorating middle warmer beneficial vigour, strong taste.Hemopoietic, granulation promoting, evacuation of pus expelling the toxic substance from the body with tonic, carbuncle sore panacea.Variola does not rise, and yang deficiency should it without hot person." " herbal justice ": " and the Radix Astragali, soil in tonification, replenishing vital QI with drugs of warm nature taste, all middle gas is depressed, and spleen soil is weak, and sagging person is the most suitable for clearing heat in QI system.The through people's of its skin skin table muscle, solid protection is defended sun, enriches table point, is its speciality, thus all diseases of exterior deficiency, the most refreshing agent." function consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.The Radix Astragali strengthens heart contraction ability, can improve the blood circulation of whole body, can coronary artery dilator, kidney blood vessel and Rhizoma Bistortae peripheral vessel, make cutaneous circulation vigorous; Can improve the nonspecific immunity power of body, protect the liver and fall hypoglycemic effect, staphylococcus, blood dissolubility streptococcus, Diplococcus pneumoniae, dysentery bacterium etc. are had to inhibitory action.The Radix Astragali can appreciable impact splenocyte Information Conduction, realizes immunoregulation effect.Can be used for hypertension, ischemic heart desease, acute glomerulonephritis, gastric ulcer, psoriasis, diabetes, osteoporosis.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature, enter spleen, stomach warp, there is spleen reinforcing promoting the circulation of QI, dampness diuretic, strengthening superficial resistance to stop perspiration, effect that activating the spleen is moisturized, cures mainly the feeling of fullness diarrhoea due to dysfunction of the spleen in transportation, QI failing to transform into body fluid, phlegm retention edema; The vexed lazy speech of deficiency of QI in middle-JIAO, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, sweating due to debility spontaneous perspiration, the Rhizoma Atractylodis Macrocephalae can promote gastric secretion, strengthens the Absorption of small intestinal, and gastrointestinal function is had to regulating action.There is obvious and lasting diuresis, various animals are had to effect as rat, rabbit, Canis familiaris L..To not anaesthetizing Canis familiaris L. intravenous injection decoct 0.05-0.25g/kg, the increase of urine amount can reach more than 9 times, and medication after 5 hours still higher than normally.The Rhizoma Atractylodis Macrocephalae has obvious inhibitory action to platelet aggregation, Rhizoma Atractylodis Macrocephalae decoct 0.5g/kg gavage l-4 week, the time of energy significant prolongation rat prothrombing.The Rhizoma Atractylodis Macrocephalae has vasorelaxation action.
Semen Lablab Album: sweet light, tepor, flat; Return spleen channel, stomach warp.Spleen invigorating, removing dampness, relieves summer heat.Cure mainly insufficiency of the spleen resulting in production of dampness, anorexia and loose stool, leukorrhagia, heat-damp in summer is vomited and diarrhoea, and excessive thirst is uncomfortable in chest.。Semen Lablab Album control heat-damp in summer vomit and diarrhoea, summer heat usually accompanied with dampness, summer heat-damp in summer damaging the spleen and stomach, incoordination between the spleen and stomach, easily causes vomiting and diarrhoea.The invigorating the spleen for eliminating dampness of Semen Lablab Album energy with in.Semen Lablab Album is controlled syndrome of deficiency of spleen qi, and Semen Lablab Album energy QI invigorating is with spleen invigorating, auxiliary using Semen Lablab Album as the medicine such as Radix Ginseng, the Rhizoma Atractylodis Macrocephalae.Semen Lablab Album also can be used for the leukorrhagia of insufficiency of the spleen turbid damp bet.The dull and stereotyped paper disk method of 100% Semen Lablab Album decoct, to dysentery bacterium with there is an inhibitory action; Vomiting, acute gastroenteritis etc. that alimentary toxicosis is caused have Detoxication.The cold salt immersion of 20% Semen Lablab Album 0.3ml, to the facilitation that is formed with of active E-rosette, strengthens the lymphocytic activity of T, improves the immunologic function of cell.Can distinguish the erythrocyte of people and sheep, cattle with the agglutinin that Semen Lablab Album extracts, because of only coagulation people's erythrocyte of agglutinin for this reason, legal medical expert can survey human blood with this.
Radix Et Caulis Acanthopanacis Senticosi: acrid in the mouth, hardship, micro-sweet, warm in nature, enter spleen, kidney, heart channel, there is replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, be slow in action, a little less than body weakness with emaciation, traumatic injury, fracture, edema, beriberi, the uncontrolled urination card such as itch.The sweet A of Radix Et Caulis Acanthopanacis Senticosi is also containing this constituents in carotene ， Ren Ginseng.In human body, can promote the excretion of cholesterol, can prevent and treat Blood Cholesterol too high levels disease.The sweet B of Radix Et Caulis Acanthopanacis Senticosi is Syringa oblata Lindl. element (Syringin), is the main strong composition of Radix Et Caulis Acanthopanacis Senticosi, has short gonad, radioprotective, fatigue-resisting function, has the physiologically active similar to Ren Ginseng Saponin.Radix Et Caulis Acanthopanacis Senticosi is containing super oxidation disproportionation ferment SOD (Superoxide dimutase) complex, SOD has good anti-oxidation function, can strengthen the effect that human immunity and opposing free radical are attacked, there is antioxidation, can strengthen body immunity, prevent aging and promotion health.
Herb Gynostemmae Pentaphylli: sweet in the mouth, hardship, cold nature; Return lung meridian, spleen channel, kidney channel.Energy QI invigorating, calms the nerves, blood pressure lowering, heat-clearing and toxic substances removing, eliminating phlegm and stopping cough.After small number of patients is taken medicine, there is the symptoms such as nausea and vomiting, abdominal distention diarrhoea (or constipation), dizziness, dim eyesight, tinnitus.Take after Herb Gynostemmae Pentaphylli, enterogastric peristalsis is accelerated, and it is long that appetite increases the resistance to time of hungering and thirst, and not only treats constipation but also control loose stool.Reaction excited to cerebral cortex and that suppress can keep suitable balance, and nervus centralis is had to dual regulation.There is good analgesia, sleep peacefully, antitonic effect.Reducing myocardial wall anxiety, relaxing on the basis of cerebrovascular and peripheral vascular resistance, can strengthen heart and brain vigor, strengthen coronary flow, relax arteriosclerosis, impel entirety circulation more vigorous and smooth.Experiment showed, not that diet is rich and take Herb Gynostemmae Pentaphylli group, and avoid meat and refuse to obey Herb Gynostemmae Pentaphylli group, make regular check on comparison, body inner bag is solid close with neutral fat content.Herb Gynostemmae Pentaphylli has optimum conversion regulating action to body fat mass in human body as can be seen here.Take the mouse comparison of Herb Gynostemmae Pentaphylli and disobedience, the approximately long 31-57% of its swimming time, and antisecosis is also faster, people takes after Herb Gynostemmae Pentaphylli, and physical energy is more abundant, and even indefatigability be also easy to recover tired, thereby work efficiency increases.Human body part function weakness, can produce allergy to Cucumber, and forms the diseases such as bronchus is panted, skin rashes, arthralgia, and Herb Gynostemmae Pentaphylli is rather good to these sick effects.
Herba clinopodii confinis (Herba Clinopodii Gracilis): bitter in the mouth; Pungent; Cool in nature.Function cures mainly: expelling wind and clearing away heat; Promoting flow of QI and blood; Removing toxic substances and promoting subsidence of swelling.Main cold, fever; Abdominal pain due to retention of food; Vomiting; Have loose bowels; Dysentery; Diphtheria; Laryngopharynx swelling and pain; Carbuncle erysipelas; Urticaria; Insect-bite; Traumatic injury wound is hemorrhage.
Testa dolichoris: sweetness and bitterness; Temperature.Return spleen; Large intestine channel.Function cures mainly: the removing dampness of relieving summer heat, invigorating the spleen and regulating the stomach.In main heat-damp in summer, accumulate, vomiting is had loose bowels, uncomfortable in chest indigestion and loss of appetite, beriberi edema, women's leukorrhagia.
Radix Scrophulariae: sweet, bitter, salty, be slightly cold.Return lung, stomach, kidney channel.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Folium Viticis Negundo: acrid in the mouth; Bitter; Cool in nature.Return lung; Liver; Small intestine meridian.Function cures mainly: the heat radiation of inducing sweat; Removing dampness for regulating stomach; Killing parasites for relieving itching.Main cold, fever; Sunstroke leaf rushes down; Eruptive disease stomachache; Intestinal inflammation; Dysentery; Malaria; Eczema; Tinea; Scabies; Snake bite and insect sting.
Caulis et Folium Crotalariae Assamicae: light; Cold.Return lung; Spleen channel.Function cures mainly: heat-clearing and toxic substances removing, cooling blood for hemostasis, inducing diuresis to remove edema.Main children's's head sore, aphtha, toothache, cough due to lung-heat's spitting of blood, traumatic injury, traumatic hemorrhage, edema, renal calculus, cystitis, rheumatic ostalgia.
Crusta Bombycis ovum: sweet in the mouth; Property is put down.Return liver; Heart channel.Function cures mainly: hemostasis; Dysentery relieving; Removing toxic substances and promoting subsidence of swelling.Main haematemesis; Epistaxis; Metrorrhagia; Perianal abscess hematochezia; Dysentery; Swelling throat numbness; Ulcerative gingivitis; Aphtha; Ting ear; Skin infection; Furuncle is swollen.
Herba Galii Teneri: acrid in the mouth; Micro-hardship; Cold nature.Return Shao Yin; Taiyin channels.Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis for treating stranguria syndrome; Reducing swelling and alleviating pain.Main swollen ulcer drug; Mastitis; Appendicitis; Edema; Cold, fever; Dysentery; Urinary tract infection; Hematuria; Gingival hemorrhage; Knife injury is hemorrhage.
Semen vignae sinensis: sweet in the mouth; Salty; Property is put down.Return: spleen; Kidney channel.Function cures mainly: invigorating spleen to remove dampness; The kidney invigorating arresting seminal emission.Main weakness of the spleen and stomach; Have loose bowels; Dysentery; Tell contrary; Quench one's thirst; Lumbago due to renal deficiency; Seminal emission; Leucorrhea; Nebulousurine; Frequent micturition.
Massa Medicata Fermentata: sweet in the mouth, pungent, warm in nature, enter spleen, stomach warp, has digestion-promoting spleen-invigorating, reduces phlegm, the effect such as blood-activating analgetic.Be mainly used in dyspepsia and do not change, distension and fullness in the abdomen, the symptoms such as lack of appetite diarrhoea, spleen fortune is lost to the phlegm syndrome due to being good for, and blood stasis pain have certain curative effect.
Radix Bupleuri: reconciling superficies and interior, soothing the liver, yang invigorating.Control alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste deafness, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.1. " herbal classic ": " stagnation of QI in main trusted subordinate's the intestines and stomach, diet gathers, and cold and heat pathogen, pushes away Chen Zhixin." 2. " not Lu ": ", except dysphoria with smothery sensation under the typhoid fever heart, all expectorant accumulation of heats are real, evil contrary in the heart, five hide between faint breath, large intestine stops amassing, watery distension, and arthralgia chiefly caused by damp pathogen contracture.Also can bathe soup." 3. " property of medicine opinion ": " Zhi Relao arthralgia with restlessness, steam, shoulder and back ache, declares smooth vim and vigour, tired weakness and emaciation; The main therapeutic method to keep the adverse QI flowing downwards helps digestion, and when main, in disease, exterior-heat is not understood, and singly boils clothes." 4. " prescriptions worth thousand gold ": " Seedling juice is controlled deafness, fills with in ear.Painful abdominal mass in " 5. " four tones of standard Chinese pronunciation book on Chinese herbal medicine ": " main expectorant billows, the breast side of body." 6. " Japan hanako materia medica ": " mends five kinds of strain and seven kinds of impairment, relieving restlessness spasmolytic, and physical strength profiting, expectorant antitussive, moistens cardiopulmonary, adds essence and mends marrow, and it the warm disease of row is fanatical weary exhausted, and breast side of body fullness caused by stagnant QI is forgetful." 7. " pearl sac ": " removes alternate attacks of chills and fever, gallbladder numbness, and non-Radix Bupleuri mortise pin can not remove." 8. " medicine origin ": ", except asthenia dysphoria with smothery sensation, dismisses flesh heat, removes hectic fever in morning." 9. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " typhoid fever relieving the exterior syndrome by diaphoresis key medicine, moves back the contact of the six channels pathogenic heat, numbness flaccidity, and except liver man pathogenic heat, consumptive disease heat, the gas of the contrary knot of row Liver Channel, only left flank irritability pain, controls married woman's heat in blood and burns warp, can adjust menstruation.The tender stamen of " " diaphoresis, controls deficiency-heat, regulating menstruation root." 10. " detailed outline ": " controlled yang-energy and sunk, and suppressing the hyperactive liver, gallbladder, three warmers, envelope be fire mutually, and headache, dizzy, and blurred vision, swelling pain are hidden from view, deaf ring, all malarias, and lump at the left hypochondrium cold and heat, married woman's invasion of the blood-chamber by heat, irregular menstruation, children's's varioliform exanthema waste heat, the thin heat of five kinds of child malnutrition."
Herba polygoni senticosi: hardship; Acid; Micro-pungent; Property is put down.Function cures mainly: heat-clearing and toxic substances removing; With wet antipruritic; Dissipating blood stasis for subsidence of swelling.Main carbuncle skin ulcer furuncle furuncle; Venom; Eczema; Impetigo; Herpes zoster; Traumatic injury; Pleased, internal hemorrhoid external hemorrhoid.
 
Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Flos Chrysanthemi Indici 10-25 weight portion, Caulis Perillae 5-15 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Angelicae Dahuricae 8-17 weight portion, Herba Centipedae 10-25 weight portion, Ramulus et Folium Tamaricis 8-15 weight portion, Rhizoma Ligustici 10-16 weight portion, Radix Pulsatillae 10-20 weight portion, Herba Lobeliae Chinensis 5-15 weight portion, Zaocys 8-20 weight portion, Radix Clematidis 5-10 weight portion, Herba Aristolochiae Mollissimae 8-15 weight portion, Herba Lycopodii 10-20 weight portion, Rhizoma Zingiberis 10-25 weight portion, Pericarpium Zanthoxyli 8-15 weight portion, Pericarpium Citri Reticulatae 10-20 weight portion, Radix Aristolochiae 5-10 weight portion, Radix Et Rhizoma Nardostachyos 15-25 weight portion, Fructus Crataegi 10-25 weight portion, fevervine 8-17 weight portion, Resina Ferulae 8-15 weight portion, Radix Astragali 10-20 weight portion, Rhizoma Atractylodis Macrocephalae 10-20 weight portion, Semen Lablab Album 10-15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15-20 weight portion, Herb Gynostemmae Pentaphylli 5-15 weight portion, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15-25 weight portion, Testa dolichoris 10-25 weight portion, Radix Scrophulariae 10-25 weight portion, Folium Viticis Negundo 15-20 weight portion, Caulis et Folium Crotalariae Assamicae 8-17 weight portion and Crusta Bombycis ovum 10-20 weight portion.
In described medicine, the parts by weight of each raw medicinal material can also be preferably: Flos Chrysanthemi Indici 17 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 15 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 17 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 13 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 10 weight portions, Zaocys 14 weight portions, Radix Clematidis 7 weight portions, Herba Aristolochiae Mollissimae 11 weight portions, Herba Lycopodii 15 weight portions, Rhizoma Zingiberis 17 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 15 weight portions, Radix Aristolochiae 7 weight portions, Radix Et Rhizoma Nardostachyos 20 weight portions, Fructus Crataegi 17 weight portions, fevervine 12 weight portions, Resina Ferulae 12 weight portions, the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 17 weight portions, Herb Gynostemmae Pentaphylli 10 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 20 weight portions, Testa dolichoris 17 weight portions, Radix Scrophulariae 18 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 12 weight portions and Crusta Bombycis ovum 15 weight portions.
In described medicine, the parts by weight of each raw medicinal material can be preferably again: Flos Chrysanthemi Indici 10 weight portions, Caulis Perillae 15 weight portions, Radix Saposhnikoviae 20 weight portions, the Radix Angelicae Dahuricae 17 weight portions, Herba Centipedae 25 weight portions, Ramulus et Folium Tamaricis 8 weight portions, Rhizoma Ligustici 16 weight portions, the Radix Pulsatillae 20 weight portions, Herba Lobeliae Chinensis 15 weight portions, Zaocys 8 weight portions, Radix Clematidis 10 weight portions, Herba Aristolochiae Mollissimae 8 weight portions, Herba Lycopodii 20 weight portions, Rhizoma Zingiberis 25 weight portions, Pericarpium Zanthoxyli 8 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Radix Aristolochiae 5 weight portions, Radix Et Rhizoma Nardostachyos 15 weight portions, Fructus Crataegi 25 weight portions, fevervine 17 weight portions, Resina Ferulae 15 weight portions, the Radix Astragali 10 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Semen Lablab Album 15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 20 weight portions, Herb Gynostemmae Pentaphylli 15 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 25 weight portions, Testa dolichoris 10 weight portions, Radix Scrophulariae 25 weight portions, Folium Viticis Negundo 20 weight portions, Caulis et Folium Crotalariae Assamicae 17 weight portions and Crusta Bombycis ovum 10 weight portions.
In described medicine, the parts by weight of each raw medicinal material can be preferably again: Flos Chrysanthemi Indici 25 weight portions, Caulis Perillae 15 weight portions, Radix Saposhnikoviae 10 weight portions, the Radix Angelicae Dahuricae 8 weight portions, Herba Centipedae 10 weight portions, Ramulus et Folium Tamaricis 15 weight portions, Rhizoma Ligustici 10 weight portions, the Radix Pulsatillae 10 weight portions, Herba Lobeliae Chinensis 5 weight portions, Zaocys 20 weight portions, Radix Clematidis 5 weight portions, Herba Aristolochiae Mollissimae 15 weight portions, Herba Lycopodii 10 weight portions, Rhizoma Zingiberis 10 weight portions, Pericarpium Zanthoxyli 15 weight portions, Pericarpium Citri Reticulatae 10 weight portions, Radix Aristolochiae 10 weight portions, Radix Et Rhizoma Nardostachyos 25 weight portions, Fructus Crataegi 10 weight portions, fevervine 8 weight portions, Resina Ferulae 8 weight portions, the Radix Astragali 20 weight portions, the Rhizoma Atractylodis Macrocephalae 10 weight portions, Semen Lablab Album 10 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15 weight portions, Herb Gynostemmae Pentaphylli 5 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15 weight portions, Testa dolichoris 10 weight portions, Radix Scrophulariae 10 weight portions, Folium Viticis Negundo 15 weight portions, Caulis et Folium Crotalariae Assamicae 8 weight portions and Crusta Bombycis ovum 10 weight portions.
In described medicine, the parts by weight of each raw medicinal material are preferably: Flos Chrysanthemi Indici 10-25 weight portion, Caulis Perillae 5-15 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Angelicae Dahuricae 8-17 weight portion, Herba Centipedae 10-25 weight portion, Ramulus et Folium Tamaricis 8-15 weight portion, Rhizoma Ligustici 10-16 weight portion, Radix Pulsatillae 10-20 weight portion, Herba Lobeliae Chinensis 5-15 weight portion, Zaocys 8-20 weight portion, Radix Clematidis 5-10 weight portion, Herba Aristolochiae Mollissimae 8-15 weight portion, Herba Lycopodii 10-20 weight portion, Rhizoma Zingiberis 10-25 weight portion, Pericarpium Zanthoxyli 8-15 weight portion, Pericarpium Citri Reticulatae 10-20 weight portion, Radix Aristolochiae 5-10 weight portion, Radix Et Rhizoma Nardostachyos 15-25 weight portion, Fructus Crataegi 10-25 weight portion, fevervine 8-17 weight portion, Resina Ferulae 8-15 weight portion, Radix Astragali 10-20 weight portion, Rhizoma Atractylodis Macrocephalae 10-20 weight portion, Semen Lablab Album 10-15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15-20 weight portion, Herb Gynostemmae Pentaphylli 5-15 weight portion, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15-25 weight portion, Testa dolichoris 10-25 weight portion, Radix Scrophulariae 10-25 weight portion, Folium Viticis Negundo 15-20 weight portion, Caulis et Folium Crotalariae Assamicae 8-17 weight portion, Crusta Bombycis ovum 10-20 weight portion, Herba Galii Teneri 13-20 weight portion, Semen vignae sinensis 15-20 weight portion, Massa Medicata Fermentata 15-20 weight portion, Radix Bupleuri 15-25 weight portion and Herba polygoni senticosi 10-20 weight portion.
In described medicine, the parts by weight of each raw medicinal material can also be preferably: Flos Chrysanthemi Indici 15 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 12 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 16 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 12 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 11 weight portions, Zaocys 11 weight portions, Radix Clematidis 6 weight portions, Herba Aristolochiae Mollissimae 12 weight portions, Herba Lycopodii 16 weight portions, Rhizoma Zingiberis 15 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 12 weight portions, Radix Aristolochiae 6 weight portions, Radix Et Rhizoma Nardostachyos 18 weight portions, Fructus Crataegi 21 weight portions, fevervine 11 weight portions, Resina Ferulae 9 weight portions, the Radix Astragali 18 weight portions, the Rhizoma Atractylodis Macrocephalae 14 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18 weight portions, Herb Gynostemmae Pentaphylli 8 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 21 weight portions, Testa dolichoris 12 weight portions, Radix Scrophulariae 15 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 11 weight portions, Crusta Bombycis ovum 15 weight portions, Herba Galii Teneri 15 weight portions, Semen vignae sinensis 16 weight portions, Massa Medicata Fermentata 17 weight portions, Radix Bupleuri 19 weight portions and Herba polygoni senticosi 15 weight portions.
The preparation method of described medicine comprises the following steps: described raw medicinal material is mixed by proportioning, and chopping, puts into acid and alkali-resistance infusion kettle, at room temperature, together with being the above ethanol of 90 degree with alcoholic degree, flood 15-22 days, the liquid having flooded and medicinal residues are carried out to squeeze and filter, after separation, get filtrate; The heating of described filtrate is concentrated into pasty state, puts into drying in oven, cooling after with grind to form fine-powdered, obtain drug powder; Using method is: described medicine is processed into after powder to feeding after directly mixing with fish meal, the 2-6% that the addition of medicine is fish meal.
 
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure of reaching technique effect can fully understand and implement according to this.
 
Embodiment 1 medicine 1
The embodiment of the present invention provides a kind of medicine that is used for the treatment of fresh-water fishes fish molds, the parts by weight of its each raw medicinal material are: Flos Chrysanthemi Indici 17 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 15 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 17 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 13 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 10 weight portions, Zaocys 14 weight portions, Radix Clematidis 7 weight portions, Herba Aristolochiae Mollissimae 11 weight portions, Herba Lycopodii 15 weight portions, Rhizoma Zingiberis 17 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 15 weight portions, Radix Aristolochiae 7 weight portions, Radix Et Rhizoma Nardostachyos 20 weight portions, Fructus Crataegi 17 weight portions, fevervine 12 weight portions, Resina Ferulae 12 weight portions, the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 17 weight portions, Herb Gynostemmae Pentaphylli 10 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 20 weight portions, Testa dolichoris 17 weight portions, Radix Scrophulariae 18 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 12 weight portions and Crusta Bombycis ovum 15 weight portions.
The preparation method of said medicine comprises the following steps: described raw medicinal material is mixed by proportioning, and chopping, puts into acid and alkali-resistance infusion kettle, at room temperature, together with being the above ethanol of 90 degree with alcoholic degree, flood 18 days, the liquid having flooded and medicinal residues are carried out to squeeze and filter, after separation, get filtrate; The heating of described filtrate is concentrated into pasty state, puts into drying in oven, cooling after with grind to form fine-powdered, obtain drug powder; Using method is: described medicine is processed into after powder, directly mixes feeding afterwards with fish meal, the addition of medicine is fish meal 5%.
 
Embodiment 2 medicines 2
The embodiment of the present invention provides a kind of medicine that is used for the treatment of fresh-water fishes fish molds, and in medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 15 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 12 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 16 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 12 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 11 weight portions, Zaocys 11 weight portions, Radix Clematidis 6 weight portions, Herba Aristolochiae Mollissimae 12 weight portions, Herba Lycopodii 16 weight portions, Rhizoma Zingiberis 15 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 12 weight portions, Radix Aristolochiae 6 weight portions, Radix Et Rhizoma Nardostachyos 18 weight portions, Fructus Crataegi 21 weight portions, fevervine 11 weight portions, Resina Ferulae 9 weight portions, the Radix Astragali 18 weight portions, the Rhizoma Atractylodis Macrocephalae 14 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18 weight portions, Herb Gynostemmae Pentaphylli 8 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 21 weight portions, Testa dolichoris 12 weight portions, Radix Scrophulariae 15 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 11 weight portions, Crusta Bombycis ovum 15 weight portions, Herba Galii Teneri 15 weight portions, Semen vignae sinensis 16 weight portions, Massa Medicata Fermentata 17 weight portions, Radix Bupleuri 19 weight portions and Herba polygoni senticosi 15 weight portions.
The preparation method of said medicine comprises the following steps: described raw medicinal material is mixed by proportioning, and chopping, puts into acid and alkali-resistance infusion kettle, at room temperature, together with the ethanol that is 95% with alcoholic degree, flood 20 days, the liquid having flooded and medicinal residues are carried out to squeeze and filter, after separation, get filtrate; The heating of described filtrate is concentrated into pasty state, puts into drying in oven, cooling after with grind to form fine-powdered, obtain drug powder; Using method is: described medicine is processed into after powder, directly mixes feeding afterwards with fish meal, the addition of medicine is fish meal 5%.
 
Clinical trial
(1) material is prepared:
Experiment fish and place are chosen
Selecting freshwater fish culturing field, Jining City in Shandong Province is Experimental Base, choose that 400 urosome shapes are even, body colour is normal, vigor is good and body weight at the during Wintering Period Ctenopharyngodon idellus of 1kg left and right as preventing contrast experiment's object; Choose at random that 36 urosome shapes are even, body colour is normal, vigor is good and body weight at the Ctenopharyngodon idellus of 1.5kg left and right as treatment contrast test object.
(2) strain culturing
The fish molds bacterial strain that certain animals and plants cause of disease storehouse is provided is transferred on the culture dish of potato dextrose agar, 18 DEG C of cultivations make it be paved with whole culture dish for 72 hours, the water mo(u)ld culture medium that takes a morsel is put into the vessel that fill pure water, and the niblet of decocting in water cracking is put into water, observe 72 hours, finding more than 90% has fish molds to grow on niblet, showing has fish molds to exist in vessel, do not put on the blank vessel niblet of culture medium simultaneously and do not have fish molds to occur, illustrate that the propagation of fish molds is cultivated fish molds since then.The fish molds of cultivating is for subsequent use.
(3) prevention contrast test:
The Ctenopharyngodon idellus of 400 tail 1kg left and right of random choose is divided into four groups at random, is respectively experimental group 1, experimental group 2, matched group and blank group, every group of 100 tail Ctenopharyngodon idellus, average weight is 1.0kg, and every group adopts the identical fishpond of size to cultivate.Wherein, experimental group 1 and experimental group 2 use respectively the forage feed Ctenopharyngodon idellus 10 days that is mixed with the embodiment of the present invention 1 medicine 1 and embodiment 2 medicines 2; Matched group uses conventional feed to feed 10 days, and within each two days in the fishpond of matched group, splash 0.04% Sal and 0.04% sodium bicarbonate mixture; Blank group is used conventional feed to feed 10 days.Each experimental group was fed respectively after ten days, in the fishpond of each experimental group, sneaked into the culture medium with fish molds, observe 10 days, and ill number and the death toll of adding up each experimental group Ctenopharyngodon idellus, result is as shown in table 1.
Table 1 prevents comparative test result synopsis tail
Group Total mantissa Ill number Prevalence Death toll Mortality rate Protective rate
Experimental group 1 100 8 8% 2 2% 92%
Experimental group 2 100 5 5% 1 1% 95%
Matched group 100 31 31% 11 11% 69%
Blank group 100 57 57% 19 19% 43%
From the data of table 1, because Ctenopharyngodon idellus is in during Wintering Period, and fishpond is relatively little, and after artificial challenge, blank group is not taked any prevention and treatment measure, causes in ten days prevalence and mortality rate higher; Feed and adopt Sal to compare with sodium bicarbonate with using conventional feed, the feedstuff Ctenopharyngodon idellus of feeding that use contains medicine 1 of the present invention and medicine 2, has improved the preventive effect of fresh-water fishes fish molds, has obviously reduced prevalence and mortality rate.
(4) treatment contrast test
Choose three glass jars that size is identical, first water mo(u)ld culture medium is sneaked into respectively in the water of glass jar, after 72h, determine water mo(u)ld breeding, the Ctenopharyngodon idellus of 36 tail 1.5kg is divided into three groups at random, be respectively experimental group 1, experimental group 2 and matched group, every group of 12 tails, both sides, Ctenopharyngodon idellus below scale is removed with knife blade, go out to scrape off the osculum of 1cm left and right at muscle, Ctenopharyngodon idellus after scratch is put into respectively to glass jar, all feed according to traditional thinking mode, all there is fish molds in each experimental group Ctenopharyngodon idellus wound two days later, change afterwards feeding patterns: experimental group 1 uses the conventional feed of the medicine 1 that is mixed with the embodiment of the present invention 1 to feed in a conventional manner, experimental group 2 uses the conventional feed of the medicine 2 that is mixed with the embodiment of the present invention 2 to feed in a conventional manner, matched group uses conventional feed to feed, and with 0.04% Sal and 0.04% sodium bicarbonate mixture full pool spilling head.Test is ten days, and recovery from illness number and the death toll of every group of Ctenopharyngodon idellus observed and recorded to duration of test, and result is as shown in table 2.
Table 2 is treated comparative test result synopsis tail
Group Total mantissa Infect number Recovery from illness number Death toll Mortality rate
Experimental group 1 12 12 11 0 0%
Experimental group 2 12 12 12 0 0%
Matched group 12 12 7 4 33.3%
From the data of table 2, use the Drug therapy fresh-water fishes fish molds of the embodiment of the present invention 1 and embodiment 2 to there is eutherapeutic advantage, and the present invention adopts Chinese herbal treatment fresh-water fishes fish molds, Chinese medicine has the dual function of the property of medicine and trophism concurrently, both preventable disease, can improve again fertility performance, and life-time service and drug residue free and without Drug resistance.
In addition, choose 3 age 60 of healthy grass carp, be divided at random three groups, for embodiment group 1, embodiment group 2 and blank group, except normally feeding, embodiment group 1 and embodiment group 2 are used respectively throw something and feed Ctenopharyngodon idellus 7 days of 10 times of amounts of medicine 1 recommended dose of the embodiment of the present invention 1 and 10 amounts of medicine 2 recommended dose of embodiment 2, blank group is not done any special handling, during medication and after medication, healthy grass carp is without any bad or Deviant Behavior performance, and average weight recruitment is higher than blank group.
 
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.

Claims (10)

1. be used for the treatment of the medicine of fresh-water fishes fish molds, it is characterized in that, described medicine comprises following raw medicinal material: Flos Chrysanthemi Indici, Caulis Perillae, Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Centipedae, Ramulus et Folium Tamaricis, Rhizoma Ligustici, the Radix Pulsatillae, Herba Lobeliae Chinensis, Zaocys, Radix Clematidis, Herba Aristolochiae Mollissimae, Herba Lycopodii, Rhizoma Zingiberis, Pericarpium Zanthoxyli, Pericarpium Citri Reticulatae, Radix Aristolochiae, Radix Et Rhizoma Nardostachyos, Fructus Crataegi, fevervine, Resina Ferulae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Radix Et Caulis Acanthopanacis Senticosi, Herb Gynostemmae Pentaphylli, Herba clinopodii confinis (Herba Clinopodii Gracilis), Testa dolichoris, Radix Scrophulariae, Folium Viticis Negundo, Caulis et Folium Crotalariae Assamicae and Crusta Bombycis ovum.
2. the medicine that is used for the treatment of fresh-water fishes fish molds according to claim 1, is characterized in that, in described medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 10-25 weight portion, Caulis Perillae 5-15 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Angelicae Dahuricae 8-17 weight portion, Herba Centipedae 10-25 weight portion, Ramulus et Folium Tamaricis 8-15 weight portion, Rhizoma Ligustici 10-16 weight portion, Radix Pulsatillae 10-20 weight portion, Herba Lobeliae Chinensis 5-15 weight portion, Zaocys 8-20 weight portion, Radix Clematidis 5-10 weight portion, Herba Aristolochiae Mollissimae 8-15 weight portion, Herba Lycopodii 10-20 weight portion, Rhizoma Zingiberis 10-25 weight portion, Pericarpium Zanthoxyli 8-15 weight portion, Pericarpium Citri Reticulatae 10-20 weight portion, Radix Aristolochiae 5-10 weight portion, Radix Et Rhizoma Nardostachyos 15-25 weight portion, Fructus Crataegi 10-25 weight portion, fevervine 8-17 weight portion, Resina Ferulae 8-15 weight portion, Radix Astragali 10-20 weight portion, Rhizoma Atractylodis Macrocephalae 10-20 weight portion, Semen Lablab Album 10-15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15-20 weight portion, Herb Gynostemmae Pentaphylli 5-15 weight portion, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15-25 weight portion, Testa dolichoris 10-25 weight portion, Radix Scrophulariae 10-25 weight portion, Folium Viticis Negundo 15-20 weight portion, Caulis et Folium Crotalariae Assamicae 8-17 weight portion and Crusta Bombycis ovum 10-20 weight portion.
3. the medicine that is used for the treatment of fresh-water fishes fish molds according to claim 1 and 2, it is characterized in that, in described medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 17 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 15 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 17 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 13 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 10 weight portions, Zaocys 14 weight portions, Radix Clematidis 7 weight portions, Herba Aristolochiae Mollissimae 11 weight portions, Herba Lycopodii 15 weight portions, Rhizoma Zingiberis 17 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 15 weight portions, Radix Aristolochiae 7 weight portions, Radix Et Rhizoma Nardostachyos 20 weight portions, Fructus Crataegi 17 weight portions, fevervine 12 weight portions, Resina Ferulae 12 weight portions, the Radix Astragali 15 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 17 weight portions, Herb Gynostemmae Pentaphylli 10 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 20 weight portions, Testa dolichoris 17 weight portions, Radix Scrophulariae 18 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 12 weight portions and Crusta Bombycis ovum 15 weight portions.
4. according to the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-3 any one, it is characterized in that, in described medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 10 weight portions, Caulis Perillae 15 weight portions, Radix Saposhnikoviae 20 weight portions, the Radix Angelicae Dahuricae 17 weight portions, Herba Centipedae 25 weight portions, Ramulus et Folium Tamaricis 8 weight portions, Rhizoma Ligustici 16 weight portions, the Radix Pulsatillae 20 weight portions, Herba Lobeliae Chinensis 15 weight portions, Zaocys 8 weight portions, Radix Clematidis 10 weight portions, Herba Aristolochiae Mollissimae 8 weight portions, Herba Lycopodii 20 weight portions, Rhizoma Zingiberis 25 weight portions, Pericarpium Zanthoxyli 8 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Radix Aristolochiae 5 weight portions, Radix Et Rhizoma Nardostachyos 15 weight portions, Fructus Crataegi 25 weight portions, fevervine 17 weight portions, Resina Ferulae 15 weight portions, the Radix Astragali 10 weight portions, the Rhizoma Atractylodis Macrocephalae 20 weight portions, Semen Lablab Album 15 weight portions, Radix Et Caulis Acanthopanacis Senticosi 20 weight portions, Herb Gynostemmae Pentaphylli 15 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 25 weight portions, Testa dolichoris 10 weight portions, Radix Scrophulariae 25 weight portions, Folium Viticis Negundo 20 weight portions, Caulis et Folium Crotalariae Assamicae 17 weight portions and Crusta Bombycis ovum 10 weight portions.
5. according to the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-4 any one, it is characterized in that, in described medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 25 weight portions, Caulis Perillae 15 weight portions, Radix Saposhnikoviae 10 weight portions, the Radix Angelicae Dahuricae 8 weight portions, Herba Centipedae 10 weight portions, Ramulus et Folium Tamaricis 15 weight portions, Rhizoma Ligustici 10 weight portions, the Radix Pulsatillae 10 weight portions, Herba Lobeliae Chinensis 5 weight portions, Zaocys 20 weight portions, Radix Clematidis 5 weight portions, Herba Aristolochiae Mollissimae 15 weight portions, Herba Lycopodii 10 weight portions, Rhizoma Zingiberis 10 weight portions, Pericarpium Zanthoxyli 15 weight portions, Pericarpium Citri Reticulatae 10 weight portions, Radix Aristolochiae 10 weight portions, Radix Et Rhizoma Nardostachyos 25 weight portions, Fructus Crataegi 10 weight portions, fevervine 8 weight portions, Resina Ferulae 8 weight portions, the Radix Astragali 20 weight portions, the Rhizoma Atractylodis Macrocephalae 10 weight portions, Semen Lablab Album 10 weight portions, Radix Et Caulis Acanthopanacis Senticosi 15 weight portions, Herb Gynostemmae Pentaphylli 5 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15 weight portions, Testa dolichoris 10 weight portions, Radix Scrophulariae 10 weight portions, Folium Viticis Negundo 15 weight portions, Caulis et Folium Crotalariae Assamicae 8 weight portions and Crusta Bombycis ovum 10 weight portions.
6. according to the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-5 any one, it is characterized in that, described medicine also comprises Herba Galii Teneri, Semen vignae sinensis, Massa Medicata Fermentata, Radix Bupleuri and Herba polygoni senticosi.
7. according to the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-6 any one, it is characterized in that, in described medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 10-25 weight portion, Caulis Perillae 5-15 weight portion, Radix Saposhnikoviae 10-20 weight portion, Radix Angelicae Dahuricae 8-17 weight portion, Herba Centipedae 10-25 weight portion, Ramulus et Folium Tamaricis 8-15 weight portion, Rhizoma Ligustici 10-16 weight portion, Radix Pulsatillae 10-20 weight portion, Herba Lobeliae Chinensis 5-15 weight portion, Zaocys 8-20 weight portion, Radix Clematidis 5-10 weight portion, Herba Aristolochiae Mollissimae 8-15 weight portion, Herba Lycopodii 10-20 weight portion, Rhizoma Zingiberis 10-25 weight portion, Pericarpium Zanthoxyli 8-15 weight portion, Pericarpium Citri Reticulatae 10-20 weight portion, Radix Aristolochiae 5-10 weight portion, Radix Et Rhizoma Nardostachyos 15-25 weight portion, Fructus Crataegi 10-25 weight portion, fevervine 8-17 weight portion, Resina Ferulae 8-15 weight portion, Radix Astragali 10-20 weight portion, Rhizoma Atractylodis Macrocephalae 10-20 weight portion, Semen Lablab Album 10-15 weight portion, Radix Et Caulis Acanthopanacis Senticosi 15-20 weight portion, Herb Gynostemmae Pentaphylli 5-15 weight portion, Herba clinopodii confinis (Herba Clinopodii Gracilis) 15-25 weight portion, Testa dolichoris 10-25 weight portion, Radix Scrophulariae 10-25 weight portion, Folium Viticis Negundo 15-20 weight portion, Caulis et Folium Crotalariae Assamicae 8-17 weight portion, Crusta Bombycis ovum 10-20 weight portion, Herba Galii Teneri 13-20 weight portion, Semen vignae sinensis 15-20 weight portion, Massa Medicata Fermentata 15-20 weight portion, Radix Bupleuri 15-25 weight portion and Herba polygoni senticosi 10-20 weight portion.
8. according to the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-7 any one, it is characterized in that, in described medicine, the parts by weight of each raw medicinal material are: Flos Chrysanthemi Indici 15 weight portions, Caulis Perillae 10 weight portions, Radix Saposhnikoviae 12 weight portions, the Radix Angelicae Dahuricae 13 weight portions, Herba Centipedae 16 weight portions, Ramulus et Folium Tamaricis 11 weight portions, Rhizoma Ligustici 12 weight portions, the Radix Pulsatillae 15 weight portions, Herba Lobeliae Chinensis 11 weight portions, Zaocys 11 weight portions, Radix Clematidis 6 weight portions, Herba Aristolochiae Mollissimae 12 weight portions, Herba Lycopodii 16 weight portions, Rhizoma Zingiberis 15 weight portions, Pericarpium Zanthoxyli 11 weight portions, Pericarpium Citri Reticulatae 12 weight portions, Radix Aristolochiae 6 weight portions, Radix Et Rhizoma Nardostachyos 18 weight portions, Fructus Crataegi 21 weight portions, fevervine 11 weight portions, Resina Ferulae 9 weight portions, the Radix Astragali 18 weight portions, the Rhizoma Atractylodis Macrocephalae 14 weight portions, Semen Lablab Album 12 weight portions, Radix Et Caulis Acanthopanacis Senticosi 18 weight portions, Herb Gynostemmae Pentaphylli 8 weight portions, Herba clinopodii confinis (Herba Clinopodii Gracilis) 21 weight portions, Testa dolichoris 12 weight portions, Radix Scrophulariae 15 weight portions, Folium Viticis Negundo 17 weight portions, Caulis et Folium Crotalariae Assamicae 11 weight portions, Crusta Bombycis ovum 15 weight portions, Herba Galii Teneri 15 weight portions, Semen vignae sinensis 16 weight portions, Massa Medicata Fermentata 17 weight portions, Radix Bupleuri 19 weight portions and Herba polygoni senticosi 15 weight portions.
9. according to the preparation method of the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-8 any one, it is characterized in that, described preparation method comprises the following steps: described raw medicinal material is mixed by proportioning, chopping, put into acid and alkali-resistance infusion kettle, at room temperature, flood 15-22 days together with being the above ethanol of 90 degree with alcoholic degree, the liquid having flooded and medicinal residues are carried out to squeeze and filter, after separation, get filtrate; The heating of described filtrate is concentrated into pasty state, puts into drying in oven, cooling after with grind to form fine-powdered, obtain drug powder.
10. according to the using method of the medicine that is used for the treatment of fresh-water fishes fish molds described in claim 1-9 any one, it is characterized in that, described medicine is processed into after powder, feeding after directly mixing with fish meal, the 2-6% that the addition of medicine is fish meal.
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CN104208435A (en) * 2014-09-15 2014-12-17 山东新希望六和集团有限公司 Pharmaceutical composition for preventing and treating branchiomycosis of carps and preparation method of pharmaceutical composition
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CN107047962A (en) * 2017-05-16 2017-08-18 广东海因特生物技术集团有限公司 It is a kind of to prevent and treat feed addictive that bream red skin disease becomes and its preparation method and application
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CN107307232A (en) * 2017-07-20 2017-11-03 通化师范学院 It is a kind of to prevent and treat Chinese herbal feed additive of saprolegniasis and application thereof in trout breeding process
CN116942710A (en) * 2023-06-16 2023-10-27 北京生泰尔科技股份有限公司 Traditional Chinese medicine extract and application thereof in preparation of products for preventing, relieving or treating common fish virus diseases

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