CN105617268A

CN105617268A - Medicine for treating scale keratinization type beriberi

Info

Publication number: CN105617268A
Application number: CN201610088089.0A
Authority: CN
Inventors: 蒋玉群
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-17
Filing date: 2016-02-17
Publication date: 2016-06-01

Abstract

The invention discloses medicine for treating scale keratinization type beriberi. The medicine comprises, by weight, 16-28 parts of cortex pseudolaricis, 16-28 parts of radix stemonae, 16-28 parts of cortex phellodendri, 16-28 parts of tobacco, 16-28 parts of pericarpium citri reticulatae, 16-28 parts of radix curcuma, 16-28 parts of impatiens balsamina, 23-36 parts of laminaria, 23-36 parts of coconut shell, 23-36 parts of fructus hordei germinatus, 23-36 parts of garlic, 23-36 parts of litsea cubeba, 23-36 parts of lemon, 23-36 parts of foeniculum vulgare, 23-36 parts of agastache rugosus and 23-36 parts of zanthoxylum bungeanum. The medicine is evident in curative effect on the scale keratinization type beriberi, capable of allowing the chapped foot skin to gradually return to the normal state, high in itching relieving ability, green and safe, and free of drug resistance generation.

Description

A kind of medicine treating squama keratinization type beriberi

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of medicine treating squama keratinization type beriberi.

Background technology

Beriberi is the popular name of tinea pedis, also referred to as " tinea pedis ", is a kind of extremely common fungal infection dermatoses. In adult, the people of 70-80% suffers from beriberi, and simply weight is different. Beriberi is everlasting and is increased the weight of summer, and winter alleviates, and also has people not heal all the year round. Medically generally beriberi is divided three types: erosive type, vesicle, squama keratinization type beriberi. Beriberi is caused by dermatophytosis such as fungus, candidiasis, mycete etc., and dermatophytosis infects usually through the publilc baths polluted, the floor of edge of pool, bath towel, public slippers, foot basin. Foot hyperhidrosis, humidity or footgear stuffiness etc. all can bring out primary disease. And beriberi and foot hyperhidrosis, foot odor are usually accompanied. When hyperhidrosis, antibacterial amount reproduction on foot also decomposes keratoprotein, adds the carbamide in perspiration, lactic acid, produces foot odor.

Squama keratinization type beriberi is apt to occur in heel, foot edge. Showing as hyperkeratosis, dry, coarse, desquamation, substrate is light red. Many monopodias occur, it is possible to biped all involves. Conscious pruritus is relatively light, pain of often chapping winter. Owing to fungal infection causes xerosis cutis, cutin slightly thick, desquamation, easily chap. Squama keratinization type beriberi is without vesicle and suppuration, and the course of disease is slow, how not to heal throughout the year, and Most patients is transformed by erosive type, vesicle.

At present, market there is no the Chinese herbal medicine being specifically designed for squama keratinization type beriberi, the unguentum of existing the medicine such as daktarin, zinci undecylenatis compositum of the treatment beriberi existed on market, the refreshing powder of foot etc, liniment, spray product, specific aim is not strong, the effect for the treatment of beriberi is poor, easily recurring after drug withdrawal, and this type of medicine is chemical synthetic drug, life-time service easily allows the malignant bacteria of squama keratinization type beriberi, fungus produce drug resistance.

Summary of the invention

For above deficiency, the present invention provides a kind of medicine treating squama keratinization type beriberi, and it overcomes the weak point of chemical synthetic drug, squama keratinization type beriberi had significant curative effect, safety non-toxic, life-time service does not produce drug resistance, is suitable for various people and uses.

A kind of medicine treating squama keratinization type beriberi, is made up of the component of following weight portion:

Cortex Pseudolaricis 16��28 parts, the Radix Stemonae 16��28 parts, Cortex Phellodendri 16��28 parts, 16��28 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 16��28 parts, 16��28 parts of Rhizoma Curcumae Longae, Flos Impatientis 16��28 parts, Thallus Laminariae (Thallus Eckloniae) 23��36 parts, Exocarpium cocois (Cocos nucifera L) 23��36 parts, 23��36 parts of Fructus Hordei Germinatus, 23��36 parts of Bulbus Allii, Fructus Litseae 23��36 parts, 23��36 parts of Fructus Citri Limoniae, 23��36 parts of Fructus Foeniculi, Herba Pogostemonis 23��36 parts, 23��36 parts of Pericarpium Zanthoxyli.

Preferably, the medicine of described treatment squama keratinization type beriberi, is made up by weight of following raw materials according: Cortex Pseudolaricis 18��25 parts, the Radix Stemonae 18��25 parts, Cortex Phellodendri 18��25 parts, 18��25 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 18��25 parts, 18��25 parts of Rhizoma Curcumae Longae, Flos Impatientis 18��25 parts, Thallus Laminariae (Thallus Eckloniae) 26��33 parts, Exocarpium cocois (Cocos nucifera L) 26��33 parts, 26��33 parts of Fructus Hordei Germinatus, 26��33 parts of Bulbus Allii, Fructus Litseae 26��33 parts, 26��33 parts of Fructus Citri Limoniae, 26��33 parts of Fructus Foeniculi, Herba Pogostemonis 26��33 parts, 26��33 parts of Pericarpium Zanthoxyli.

More preferably, the medicine of described treatment squama keratinization type beriberi, is made up by weight of following raw materials according: Cortex Pseudolaricis 22 parts, the Radix Stemonae 22 parts, Cortex Phellodendri 22 parts, 22 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 22 parts, 22 parts of Rhizoma Curcumae Longae, Flos Impatientis 22 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, Exocarpium cocois (Cocos nucifera L) 30 parts, 30 parts of Fructus Hordei Germinatus, 30 parts of Bulbus Allii, Fructus Litseae 30 parts, 30 parts of Fructus Citri Limoniae, 30 parts of Fructus Foeniculi, Herba Pogostemonis 30 parts, 30 parts of Pericarpium Zanthoxyli.

The dosage form of Chinese herbal medicine of the present invention can be the medically acceptable dosage forms such as lotion, tincture, cream, ointment, plaster, and their preparation method, supplementary product consumption are undertaken by existing common process.

In herbal prescription of the present invention:

Cortex Pseudolaricis, is again Cortex Pseudolaricis, pseudolaricis,cortex, is conventional Chinese medicine. Cortex Pseudolaricis tincture is containing Cortex Pseudolaricis acid about 0.8%. Another name: Cortex Pseudolaricis, Jing Pishu. Derive from root bark and the near root bark of pinaceae plant golden larch pseudolarixamabilis (Nelson) Regd. [p.kaempferiGord]. Cure mainly: Anti-Puritic and insecticidal. For trick tinea, neurodermatitis, eczema, leprosy dysentery head. Put on the skin outside external root bark or near root bark steeping in wine (Cortex Pseudolaricis tincture); Or finely ground powder dresses affected part with vinegar. Medicinal part, the bark of golden larch or root bark. Meridian distribution of property and flavor, pungent, temperature. Poisonous. Return lung meridian. Effect is classified, anthelmintic. Effect, Anti-Puritic and insecticidal. Cure mainly trick tinea, local neurodermatitis, eczema, leprosy dysentery head. Usage and dosage, infusing drugs in wine is embrocated or is ground into powder and dresses.

The Radix Stemonae (Classification system: Stemonajaponica) is also known as mother-in-law woman grass, and medicine louse medicine, is the plant of Stemonaceae. The Radix Stemonae is perennial herb, and cluster fusiform meat tuber in underground, and stem top is climbed up by holding on to its thing and risen. Chemical composition: the Radix Stemonae rich in there being substantial amounts of alkaloid, root containing (-)-Stemoninine, tuberostemonine, this for peaceful alkali, secondary (-)-Stemoninine, oxidation (-)-Stemoninine. Still sugary 2.32%, lipid 0.84%, protein 9.25%, ash 12.1%, and acetic acid, formic acid, malic acid, succinic acid, oxalic acid etc. Effect: 1, relieving cough and resolving phlegm. The multiplex Radix Stemonae treatment chronic cough of ancients, abundant expectoration, because chronic cough person's lung qi element is empty, hundred steps can nurse one's health relieving cough and resolving phlegm respectively according to cold and heat. Cough due to wind and cold then helps with Rhizoma Zingiberis Recens; Cough due to lung-heat then and honey. For diseases such as pulmonary tuberculosis, chronic cough, pulmonary tuberculosis cough, pertussis, asthma. 2, gentle lung qi. Abnormal rising of lung-QI is asthma and cough then, the Radix Stemonae bitter and under let out, kind sending down the abnormal ascending QI, it is possible to the therapeutic method to keep the adverse QI flowing downwards dissipates lung-heat, main warming the lung. For the disease such as lung cold cough, pulmonary tuberculosis. 3, heat radiation is induced sweat. The Radix Stemonae embellishes but not dry, can using pungent drugs for dispersion and bitter drugs for purgation sending down the abnormal ascending QI, clearing away lung-heat and induce sweat, for diseases such as skin scabies, eczema, psoriasis, general edema with yellowish skin all over, dermatitis, eczemas. 4, parasite killing delousing. Recording according to Qing Dynasty's medical science ancient books and records " book on Chinese herbal medicine newly organized ", Radix Stemonae parasite killing and not loss QI and blood, most useful for people, but during parasite killing, requirement is a little big, could be effective. Simultaneously can reduce the damage to the intestines and stomach of the Radix Stemonae bitter in the mouth with the compatibility such as Radix Ginseng, Poria, the Rhizoma Atractylodis Macrocephalae. Outer for diseases such as head louse, body louse, pinworm, pudendal pruritus, ascariasis.

Cortex Phellodendri (hu �� ngb ��), Chinese medicine name. Dry bark for rutaceae wampee PhellodendronchinenseSchneid.. Function: have heat clearing and damp drying, pathogenic fire purging is except steaming, effect of detoxification sore treatment. Cure mainly: for damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema. Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire. For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.

Nicotiana tabacum L., annual or limited perennial herb, Solanaceae. Effect: 1. " the SHENGCAO property of medicine is standby to be wanted ": disappear general edema with yellowish skin, beats medicated porridge food. 2. " south of the Five Ridges gather medicinal herbs record ": dispelling the wind and dampness pathogens foot pain, washing is decocted. 3. " Luchuan book on Chinese herbal medicine ": reducing swelling and alleviating pain, controlling treating swelling and pain by traumatic injury, infusing drugs in wine takes or mashes wine and fries deposited. 4. " Nanning City's medicine will ": parasite killing, detumescence, hemostasis. For oral administration metrorrhagia of controlling, preventing phlegm from forming and stopping coughing, toothache (pot water containing). Rotten skin ulcer is washed in external; Mash and add urine and boil, external application, control scrotum testis swelling.

Cure mainly: harness the Yellow River swollen, gout, metrorrhagia, treating swelling and pain by traumatic injury, toothache, scrofula, ulcerative carbuncle, eczema, dermatitis.

Pericarpium Citri Reticulatae, Chinese medicine name. Dry mature skin for rutaceae orange CitrusreticulataBlanco and variety thereof. Effect: the 1. effect of pair digestive system: volatile oil contained by Pericarpium Citri Reticulatae, has the stimulation of gentleness to gastrointestinal tract, can the secretion of facilitating digestion liquid, get rid of pneumatosis in intestinal tube, it is shown that the effectiveness of fragrance stomach invigorating and the wind dispelling therapeutic method to keep the adverse QI flowing downwards. 2. the effect of pair cardiovascular system: Pericarpium Citri Reticulatae decoct, ethanol extract etc. can be excited myocardium, but occur on the contrary when dosage is excessive suppressing. It addition, it also can make blood vessel produce slight contraction, rapid raising blood pressure. The arteriosclerosis that high fat diet is caused by the pectin in Pericarpium Citri Reticulatae also has certain preventive effect. 3. the effect of pair respiratory system: the irritant passive phlegm-dispelling functions of volatile oil contained by Pericarpium Citri Reticulatae, makes sputum easily bring up. Bronchus is had faint dilating effect by Pericarpium Citri Reticulatae decoct. The titer of relievining asthma of its ethanol extract is higher. 4. the effect of pair genitourinary system: Pericarpium Citri Reticulatae decoct can make Renal vascular shrink, and makes hypourocrinia. 5. antiinflammatory action: Pericarpium Citri Reticulatae decoct and vitamin C, vitamin K use, can strengthen antiinflammation.

Rhizoma Curcumae Longae (Classification system: CurcumalongaL.) has another name called: Radix Curcumae, tripod perfume, milli life, Dioscorea zingiberensis etc. Rhizoma Curcumae Longae Musales, Zingiberaceae, Curcuma herbaceos perennial, Rhizoma Curcumae Longae energy circulation of qi promoting removing blood stasis with potent drugs, inducing menstruation to relieve menalgia. Cure mainly chest and abdomen swelling and pain, take on arm arthralgia pain, pained unbearably, puerperal blood pain, skin ulcer tinea onset, menoxenia, amenorrhea, traumatic injury. Yellow food colour can be extracted again; Contained curcumin can perform an analysis chemical reagent.

Flos Impatientis, another name: Flos Impatientis, Semen Impatientis, Caulis Impatientis, Latin literary fame: ImpatiensbalsaminaL. Sapindales, Balsaminaceae, impatiens annual herb flowers, [1] Herb divides root, stem, leaf, flower, fruit and six parts of seed. Because its fresh idea, wing, tail, foot all stick up so such as phoenix shape, therefore have another name called buttercup. Stem and seed are used as medicine. Stem has wind-damp dispelling, invigorates blood circulation, the effect of pain relieving, for treating rheumatic arthralgia, joint stuffiness; Seed claims " Semen Impatientis ", has the effect of softening the hard mass, removing food stagnancy, is used for controlling dysphagic, fishbone caught in throat, abdominal mass, amenorrhea.

Thallus Laminariae (Thallus Eckloniae) is the medical herbs that " Chinese Pharmacopoeia " includes, and medicinal source is Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) or the dry thallus of Alariaceae plant Thallus Laminariae (Thallus Eckloniae) (goose palm dish). Thallus Laminariae (Thallus Eckloniae) gas raw meat, salty in the mouth. Return liver, stomach, kidney channel. There are hard masses softening and resolving, expectorant, the function of diuretic. For phlegm retention edema. Hard masses softening and resolving, expectorant, diuretic. Goiter, scrofula, painful and swollen testis, phlegm retention edema.

Exocarpium cocois (Cocos nucifera L) is the endocarp of babassu Cortex cocois radicis, and Exocarpium cocois (Cocos nucifera L) is containing ash 0.61%, lignin 36.51%, cellulose 53.06%, pentosan 29.27% (total amount). Effect: 1. " detailed outline ": syphilitic skin lesion bones and muscles pain, Exocarpium cocois (Cocos nucifera L) charred medicinal herb with its property retained, to make popular temporarily, be taken after being infused in hot water or decoction two or three money rolling wine, warm covering takes antiperspirant. 2. " detailed outline is picked up any lost article from the road ": Exocarpium cocois (Cocos nucifera L) endures cream, it is coated with tinea good. 3. " book on Chinese herbal medicine asks former ": control the cold cold and heat of folder chilly wind. 4. " China's book on Chinese herbal medicine ": dispel the wind; Pain relieving; Dampness removing; Antipruritic.

Fructus Hordei Germinatus, Chinese medicine name. It is grown in northern areas, for Preparation process product through germinateing dry of the mature fruit of grass Fructus Hordei Vulgaris HordeurnvulgareL. more. Sweet, flat. Return spleen, stomach warp. Circulation of qi promoting helps digestion, spleen benefiting and stimulating the appetite, moves back breast relieving distension. Not disappearing for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, breast antiperspirant smoulders, distending pain of the breast, and women weans. Fructus Hordei Germinatus invigorating the spleen and regulating the stomach lactogenesis, for insufficiency of the spleen lack of appetite, breast antiperspirant smoulders.

Bulbus Allii (Garlic) be again Bulbus Allii, Bulbus Allii head, giant garlic, calabash, DUSUAN, single clove garlic, is the general designation of Bulbus Allii class plant. Semi-annual herbaceous plant, Liliaceae Allium, it is used as medicine with bulb. " occupying diet spectrum with breath ": " survivor is hot, the sweet temperature of ripe person, eliminating cold-damp, wards off YIN pathogen, in lower hot air heating, and grain-meat digesting, broken stagnant blood, attack cold long-pending. Control sudden attack of spouting diarrhea stomachache, clearance lattice constipation, ward off dirty removing toxic substances, the painful abdominal mass that disappears parasite killing. Outer moxibustion carbuncle, row water is nosebleed only ". Basic drug effect: 1. strong disinfecting. In Bulbus Allii, sulfur-containing compound has strong antibacterial and anti-inflammation functions, and multiple coccus, bacillus, fungus and virus etc. all have suppression and killing action, is the one that in the current natural plants found, antibacterial action is the strongest. 2. anti-curing oncoma and cancer. The elements such as germanium in Bulbus Allii and selenium can suppress the growth of tumor cell and cancerous cell, and experiment finds, the crowd that cancer incidence is minimum is exactly the crowd that in blood, selenium content is the highest. National Cancer tissue is thought, in the plant of the most anticancer potentiality in the whole world, ranks first. 3. toxin-expelling intestine-cleaning, prevention of gastrointestinal. 4. reduce blood glucose, prevent diabetes. Bulbus Allii can promote the secretion of insulin, increases the histiocyte absorption to glucose, improves human glucose tolerance, reduces rapidly internal blood sugar level, and can kill the various pathogenic bacterias because of infection-induced diabetes, thus effectively preventing and treatment diabetes. 5. cardiovascular and cerebrovascular disease is prevented and treated. Bulbus Allii can prevent the lipidosis in cardiovascular and cerebrovascular vessel, induced tissue fat inside metabolism, dramatically increase fibrinolytic activity, reduce cholesterol, it is suppressed that hematoblastic gathering, reduce plasma concentration, increase arteriolar expansion ratio, promote vasodilation, regulate blood pressure, increase the permeability of blood vessel, thus suppressing formation and the prevention of arterial hardening of thrombosis. 6, preventing cold, is the Capsaicin of " allyl sulfides " containing one in Bulbus Allii, pathogen and parasite is had good killing action, can preventing cold, alleviate fever, cough, have sore throat and the cold symptoms such as nasal obstruction. 7, antifatigue effect, someone studies one of the food finding Carnis Sus domestica rich in vitamin B1, and vitamin B1 and the garlicin contained by Bulbus Allii combine, the effect that can well play allaying tiredness, regain one's strength. 8, anti-aging effects: some composition in Bulbus Allii has similar vitamin E and ascorbic antioxidation, anti-aging characteristic. 9, liver function protecting: the trace element-selenium in Bulbus Allii, by participating in the aerobic metabolism of blood, removing toxin, alleviating the removing toxic substances burden of liver, thus reaching liver-protective purpose. 10, vigorous energy, treatment sexual impotence: have research display Bulbus Allii really have treatment sexual impotence effect. Bulbus Allii is conducive to blood circulation, and this is critically important to erection function. Be what mechanism, can hardly be explained, it is possible to explanation be that Bulbus Allii can stimulate body to produce nitricoxide synthase, and this enzyme is enzyme necessary to male erectile. 11, anti-allergic effects: eat something rare Bulbus Allii every day and can alleviate anaphylaxis degree, particularly the allergy caused by variations in temperature. The best way is to arrive former weeks to begin to eat something rare Bulbus Allii at allergy seasons. 12, prevention women colpitis mycotica: colpitis mycotica is caused by fungal infection, Bulbus Allii draws the materials such as element containing substantial amounts of garlicin, Bulbus Allii, it it is the Fungicidal substance of natural brute force, there is great bactericidal action, Candida albicans can be suppressed in intravaginal undue growth and breeding, so the daily foods eating Bulbus Allii class of women, it is possible to the effective generation preventing colpitis mycotica. more13, improve carbohydrate metabolism: research confirms, eats Bulbus Allii raw and is improved the effect of normal person's glucose tolerance, may additionally facilitate the secretion of insulin simultaneously and increase the histiocyte producing level to glucose, thus reducing blood sugar level.

Fructus Litseae, has another name called cubeb litsen tree, Tetranthera citrata, Alpinia japonica (Thunb.) Miq., Litsea chenii, Fructus Litseae pungentis, Lauraceae, Litsea machaka or dungarunga. Fructus Litseae has effect of warming spleen and stomach for dispelling cold, regulating QI to relieve pain, can be used for the diseases such as the singultus vomiting caused by cold syndrome of the stomach, epigastric pain, can also be used for the turbid urine that colic of cold type stomachache, sympotoms caused by cold factors dysuria and children's's stagnancy of cold-damp cause, also can treat the diseases such as anemofrigid cold, cough and asthma, dyspepsia. Mash external application with Fructus Litseae leaf, cellulitis furuncle and phyma pain can be treated; The pan-fried hydro-thermal of Litsea cubeba root is applied or hot dipping can treat rheumatic ostalgia, numb limbs and tense tendons, waist-leg disease and traumatic injury. Litsea cubeba oil is alternatively arranged as the raw material of synthesising complex E, K, A etc., to play it in effect pharmaceutically. Due to litsea cubeba oil unique effect in treatment disease, also it is focus in clinical research. Additionally, Fructus Litseae also have relieving asthma, antiallergic, the anti-rhythm of the heart often, antithrombotic, antibacterial, antiviral, anti-trichomonas vaginitis effect.

Fructus Citri Limoniae (formal name used at school: Citruslimon (L.) Burm.f.), Rutaceae Citrus dungarunga plant, is a kind of fruit, also known as lemon fruit, lemon, Herba Leonuri fruit etc. The medical function of Fructus Citri Limoniae, early on the books in ancient medical book. Pharmacy man of the Ming Dynasty the shown Compendium of Material Medica of Li Shizhen (1518-1593 A.D.) is recorded Fructus Citri Limoniae have promote the production of body fluid, quench the thirst, the function such as drive away summer heat. Lemon juice, nature and flavor are bitter, warm, nontoxic. " Luchuan book on Chinese herbal medicine " says that citron fruit, skin juice etc. have thin stagnant, stomach invigorating, pain relieving, control the usefulness such as stasis stomachache anorexia. Modern medicine thinks that Fructus Citri Limoniae is the medicine food of prevention cardiovascular diseases. Owing to citric acid becomes a kind of soluble complexes in human body with calcium binding, thus alleviating calcium ion have the effect promoting blood coagulation. Therefore, hypertension, Patients With Myocardial Infarction often drink lemonade, have very big benefit to improving symptom.

Caulis et Folium Foeniculi original name again little bosom perfume, also known as fragrant silk dish, Fructus Foeniculi, aniseed, Gu Xiang (Sichuan, Guizhou) the muddy perfume (or spice) of Dian, tender leaf makes vegetables, is the stem of Fructus Foeniculi, for the dry mature fruit of samphire Fructus Foeniculi. Effect: 1, " a thousand pieces of gold dietetic therapy ": main Serpentis stings skin ulcer and is not recovered for a long time, smash deposited it. Control again nine kinds of fistulas. 2, Tang Materia Medica: main all fistulas, cholera and snakebite. 3, " Kaibao Bencao ": cold air and caecum gas between main bladder, kidney, pain relieving in tune, vomiting. 4, " Japan hanako materia medica ": control dry, beriberi caused by pathogenic damp impairment of the kidney caused by overstrain swelling of the scrotum gas, whetting the appetite (' food ' one make ' gas '), control cystodynia, cloudy pain. 5, Li Gao: mend the gate of vitality not enough. 6, " typhoid fever accumulate want ": warm public region. 7, " jade seizes medicine solution ": soil of harnessing the river is raw, lumbago beriberi, chronic diarrhea colic of cold type. 8, " book on Chinese herbal medicine is looked for the truth ": Liver Channel asthenic fire uses it from upper left punch face person. 9, " diet spectrum is occupied with breath ": parasite killing is warded off dirty, the system flesh of fish cold stagnant all poison of urine smell. 10 " Chinese medicine shape sex experience differential methods ": control chronic tracheitis. 11, " Jilin Chinese herbal medicine ": dispersing cold for relieving pain. Control hernia, renal cold lower abdominal pain, stomachache, lumbago, the enuresis.

Herba Pogostemonis, formal name used at school: Agastacherugosa (Fisch.etMey.) O.Ktze.; Have another name called: blending, grey announcement, mountain Fructus Foeniculi etc., belong to tubular flower order, Labiatae herbaceos perennial. Function: eliminating turbid pathogen with aromatics, and middle preventing or arresting vomiting, deliver expelling summer-heat. For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is vomitted, heat-damp in summer exterior syndrome, and hygropyrexia, from the beginning of, asthenia of generating heat, uncomfortable in chest is not relaxed, and cold-damp closes summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache. Herba Pogostemonis has sterilizing function, suck a leaf can antihalitosis, keep off infection, and can serve as preservative. Cooking congee with Herba Pogostemonis summer or drink-service of making tea, to heat-damp in summer serious symptom, taste dampness, distension and fullness in the abdomen, limbs are heavily tired, and nausea and vomiting is effective.

Pericarpium Zanthoxyli (formal name used at school: ZanthoxylumbungeanumMaxim.), another name:, big green pepper, Pericarpium Zanthoxyli, another name for Sichuan Province green pepper, Fructus Zanthoxyli or Pericarpium Zanthoxyli. For Rutaceae, Zanthoxylum machaka or dungarunga, isolated planting protection thorn hedge can be made again. Function: 1. " herbal classic ": main air pathogen, warming middle-JIAO, except arthralgia due to cold, hard tooth is sent out, improving eyesight. Main pathogen cough with dyspnea, warming middle-JIAO, by the dead flesh of joint skin, arthralgia due to cold-dampnes, the therapeutic method to keep the adverse QI flowing downwards. 2. " not Lu ": treat sore throat, tell inverse, hernia abdominal mass, remove old blood, disease stomachache more than puerperal, perspire, profit the five internal organs. Except six internal organs are cold, typhoid fever, pyrexial malaria, strong wind no sweating, trusted subordinate's prolonged fluid-retention, dyspepsia, intestinal trip dysentery, let out essence, disease more than woman's word breast, dissipate ailment said due to cold or exposure abdominal mass knot, edema, jaundice, parasite killing ichthyotoxin. Loosing the interspaces of skin and muscles, promoting blood circulation, hard tooth is sent out, and adjusts joint, resistance to cold and summer-heat, can make plaster. 3. " property of medicine opinion ": controlling aversion to wind, extremity insensitive impediment all over, ability to speak edema is shaken; Main woman closes obstructed the moon, stagnant blood dysentery after managing property, for many years dysentery, main hair growth promoting, treats cold type of pain in abdomen. Controlling tear under wind syndrome of head, waist foot is unsuccessful, the deficient knot that stays, removing blood stasis, under all stony edema, in abdomen cold and pain, except toothache. 4. " Treatise on Dietetic Therapy ": scar of going out, lower milk. 5. " Japan hanako materia medica ": broken crux, appetizing, control temperature disease during day row, puerperal, stagnated blood, controlled trusted subordinate's gas, tonifying YANG, treated polyhidrosis around the external genitals, warm waist knee joint, urine reducing. 6. " detailed outline ": dispelling cold and removing dampness, stagnation resolving, disappear dyspepsia, and logical three is burnt, and warming the spleen stomach is mended the right kidney gate of vitality, killed ascarid, and stopping leak rushes down.

The invention have the benefit that

Squama keratinization type beriberi is had significant curative effect by Chinese herbal medicine of the present invention, can quickly kill the malignant bacteria of blister type beriberi, fungus, recovers horny layer to normal thickness, shrink foot pore and the skin chapped, prevent foot loss of moist excessive, keep the normal moisture of pedal skin, Quick itch stopping.

Detailed description of the invention

Further explanation of the present invention is illustrated below in conjunction with specific embodiment, but the present invention is not in order to limit the present invention.

Embodiment 1

A kind of medicine treating squama keratinization type beriberi, its component is: Cortex Pseudolaricis 16 parts, the Radix Stemonae 28 parts, Cortex Phellodendri 16 parts, 28 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 16 parts, 28 parts of Rhizoma Curcumae Longae, Flos Impatientis 16 parts, Thallus Laminariae (Thallus Eckloniae) 36 parts, Exocarpium cocois (Cocos nucifera L) 23 parts, 36 parts of Fructus Hordei Germinatus, 23 parts of Bulbus Allii, Fructus Litseae 36 parts, 23 parts of Fructus Citri Limoniae, 36 parts of Fructus Foeniculi, Herba Pogostemonis 23 parts, 36 parts of Pericarpium Zanthoxyli.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 12 times amount water for the 1st time, decocts 4 hours, add 6 times amount water 2nd time, decoct 3 hours, add 3 times amount water for the 3rd time, decoct 1 hour, collecting decoction, filtering, filtrate is concentrated into the solution that relative density is 1.85 (surveying when 60 DEG C), prepares lotion.

Embodiment 2

A kind of medicine treating squama keratinization type beriberi, its component is: Cortex Pseudolaricis 28 parts, the Radix Stemonae 16 parts, Cortex Phellodendri 28 parts, 16 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 28 parts, 16 parts of Rhizoma Curcumae Longae, Flos Impatientis 28 parts, Thallus Laminariae (Thallus Eckloniae) 23 parts, Exocarpium cocois (Cocos nucifera L) 36 parts, 23 parts of Fructus Hordei Germinatus, 36 parts of Bulbus Allii, Fructus Litseae 23 parts, 36 parts of Fructus Citri Limoniae, 23 parts of Fructus Foeniculi, Herba Pogostemonis 36 parts, 23 parts of Pericarpium Zanthoxyli.

Weigh above each raw material, boiling 3 times by proportional quantity, add 6 times amount water the 1st time, decoct 2 hours, add 4 times amount water for 2nd time, decoct 1.5 hours, add 2 times amount water the 3rd time, decoct 1 hour, collecting decoction, filters, and filtrate is concentrated into the extractum that relative density is 1.5 (surveying when 70 DEG C), add medical alcohol, obtain tincture.

Embodiment 3

A kind of medicine treating squama keratinization type beriberi, its component is: Cortex Pseudolaricis 18 parts, the Radix Stemonae 25 parts, Cortex Phellodendri 18 parts, 25 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 18 parts, 25 parts of Rhizoma Curcumae Longae, Flos Impatientis 18 parts, Thallus Laminariae (Thallus Eckloniae) 33 parts, Exocarpium cocois (Cocos nucifera L) 26 parts, 33 parts of Fructus Hordei Germinatus, 26 parts of Bulbus Allii, Fructus Litseae 33 parts, 26 parts of Fructus Citri Limoniae, 33 parts of Fructus Foeniculi, Herba Pogostemonis 26 parts, 33 parts of Pericarpium Zanthoxyli.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 6 times amount water for the 1st time, decocts 2.5 hours, add 4 times amount water 2nd time, decoct 1.5 hours, add 3 times amount water for the 3rd time, decoct 1 hour, collecting decoction, filtering, filtrate is concentrated into the extractum that relative density is 1.75 (surveying when 70 DEG C), adds the aluminium-magnesium silicate cream of conventional amount used.

Embodiment 4

A kind of medicine treating squama keratinization type beriberi, its component is: Cortex Pseudolaricis 25 parts, the Radix Stemonae 18 parts, Cortex Phellodendri 25 parts, 18 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 25 parts, 18 parts of Rhizoma Curcumae Longae, Flos Impatientis 25 parts, Thallus Laminariae (Thallus Eckloniae) 26 parts, Exocarpium cocois (Cocos nucifera L) 33 parts, 26 parts of Fructus Hordei Germinatus, 33 parts of Bulbus Allii, Fructus Litseae 26 parts, 33 parts of Fructus Citri Limoniae, 26 parts of Fructus Foeniculi, Herba Pogostemonis 33 parts, 26 parts of Pericarpium Zanthoxyli.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 4 times amount water for the 1st time, decocts 2 hours, add 3 times amount water 2nd time, decoct 1.5 hours, add 2 times amount water for the 3rd time, decoct 0.5 hour, collecting decoction, filtering, filtrate is concentrated into the thick paste that relative density is 1.65 (surveying when 60 DEG C), and the sorbitol fatty acid methyl ester adjuvant adding conventional amount used prepares ointment.

Embodiment 5

A kind of medicine treating squama keratinization type beriberi, its component is: Cortex Pseudolaricis 22 parts, the Radix Stemonae 22 parts, Cortex Phellodendri 22 parts, 22 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 22 parts, 22 parts of Rhizoma Curcumae Longae, Flos Impatientis 22 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, Exocarpium cocois (Cocos nucifera L) 30 parts, 30 parts of Fructus Hordei Germinatus, 30 parts of Bulbus Allii, Fructus Litseae 30 parts, 30 parts of Fructus Citri Limoniae, 30 parts of Fructus Foeniculi, Herba Pogostemonis 30 parts, 30 parts of Pericarpium Zanthoxyli.

Above each raw material is weighed by proportional quantity, boiling 3 times, adds 3 times amount water for the 1st time, decocts 2 hours, add 2 times amount water 2nd time, decoct 1.5 hours, add 1 times amount water for the 3rd time, decoct 0.5 hour, collecting decoction, filtering, filtrate is concentrated into the thick paste that relative density is 1.85 (surveying when 60 DEG C), and the Colophonium adding conventional amount used prepares plaster.

Experimental example: the Chinese herbal medicine of the present invention clinical efficacy to blister type beriberi

Experiment material: the Chinese herbal medicine of the embodiment of the present invention 4 preparation.

Experiment place: Qinzhou healthcare hospital for women & children.

1, case and method

2010-2013, connects and controls patient 185 example, male 95 example, women 90 example, and the age is in 12-70 year. Symptom: heel, foot edge hyperkeratosis, dry, coarse, desquamation, substrate is light red, and pruritus is lighter.

Usage and dosage: the Chinese herbal medicine of the embodiment of the present invention 4 preparation, every day 3 times, takes appropriate ointment every time and is applied to affected part, and 15d is a course for the treatment of, and this experimental therapy time is 1 course for the treatment of.

2, efficacy determination

It is as the criterion according to clinical symptom disappearance, is divided into recovery from illness, effective, effective, invalid.

Recovery from illness: Clinical symptom and sign disappears, heel, foot edge cuticle thickness recover normal, and pedal skin is without desquamation phenomenon, and pruritus is wholly absent.

Effective: Clinical symptom and sign substantially or mostly disappears, heel, foot edge cuticle thickness recover normal substantially, and only a few foot horny layer does not recover normal completely, and there is a small amount of slight crack in vola.

Invalid: Clinical symptom and sign is without improvement, and foot pruritus is without substantially alleviating situation, and heel, foot edge cuticle thickness, foot edge slight crack are relatively treated front without significant change, have slight pruritis.

3, curative effect is summed up

	Recovery from illness	Effective	Invalid	Effective percentage
					After one course for the treatment of	90	6	4	96%

This therapeutic process, have no adverse reaction appearance, internal recurrence in a year after drug withdrawal. Being not difficult to find out from this experiment, squama keratinization type beriberi is had significant curative effect by Chinese herbal medicine of the present invention.

Claims

1. the medicine treating squama keratinization type beriberi, it is characterized in that, be made up of the component of following weight portion: Cortex Pseudolaricis 16��28 parts, the Radix Stemonae 16��28 parts, Cortex Phellodendri 16��28 parts, 16��28 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 16��28 parts, 16��28 parts of Rhizoma Curcumae Longae, Flos Impatientis 16��28 parts, Thallus Laminariae (Thallus Eckloniae) 23��36 parts, Exocarpium cocois (Cocos nucifera L) 23��36 parts, 23��36 parts of Fructus Hordei Germinatus, 23��36 parts of Bulbus Allii, Fructus Litseae 23��36 parts, 23��36 parts of Fructus Citri Limoniae, 23��36 parts of Fructus Foeniculi, Herba Pogostemonis 23��36 parts, 23��36 parts of Pericarpium Zanthoxyli.

2. the medicine for the treatment of squama keratinization type beriberi according to claim 1, it is characterized in that, it is made up by weight of following raw materials according: Cortex Pseudolaricis 18��25 parts, the Radix Stemonae 18��25 parts, Cortex Phellodendri 18��25 parts, 18��25 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 18��25 parts, 18��25 parts of Rhizoma Curcumae Longae, Flos Impatientis 18��25 parts, Thallus Laminariae (Thallus Eckloniae) 26��33 parts, Exocarpium cocois (Cocos nucifera L) 26��33 parts, 26��33 parts of Fructus Hordei Germinatus, 26��33 parts of Bulbus Allii, Fructus Litseae 26��33 parts, 26��33 parts of Fructus Citri Limoniae, 26��33 parts of Fructus Foeniculi, Herba Pogostemonis 26��33 parts, 26��33 parts of Pericarpium Zanthoxyli.

3. the medicine for the treatment of squama keratinization type beriberi according to claim 1, it is characterized in that, it is made up by weight of following raw materials according: Cortex Pseudolaricis 22 parts, the Radix Stemonae 22 parts, Cortex Phellodendri 22 parts, 22 parts of Nicotiana tabacum L., Pericarpium Citri Reticulatae 22 parts, 22 parts of Rhizoma Curcumae Longae, Flos Impatientis 22 parts, Thallus Laminariae (Thallus Eckloniae) 30 parts, Exocarpium cocois (Cocos nucifera L) 30 parts, 30 parts of Fructus Hordei Germinatus, 30 parts of Bulbus Allii, Fructus Litseae 30 parts, 30 parts of Fructus Citri Limoniae, 30 parts of Fructus Foeniculi, Herba Pogostemonis 30 parts, 30 parts of Pericarpium Zanthoxyli.