CN104208245B - Tinea manus and pedis Traditional Chinese medicine medicated bath and preparation method - Google Patents
Tinea manus and pedis Traditional Chinese medicine medicated bath and preparation method Download PDFInfo
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技术领域technical field
本发明涉及中医中药领域,特别是涉及一种治疗手足癣的中药药浴及制备方法。The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicinal bath for treating tinea manus and pedis and a preparation method thereof.
背景技术Background technique
手足癣是手癣和足癣的总称。手癣是指发生在手掌和指间,跖与指、趾间皮肤浅部的癣菌感染。足癣是指发生于足跖部及趾间的皮肤癣菌感染。手足癣是一种有真菌侵入手足皮肤角质层引起的皮肤病,大多数是由脚癣再感染到手部。在潮湿温暖的环境中,有利于真菌的生长和繁殖,因此极易发生在夏天南方地区的人们身上。足癣是皮肤癣菌病中最常见的疾病,多见于成人,男女皆可罹患,全世界流行,往往夏季加重,秋季减轻,若未彻底治疗,常迁延多年。在足癣发病中,缺乏皮脂腺和穿着封闭性鞋子造成的湿润环境是最重要的因素。主要的致病菌包括红色毛癣菌、须癣毛癣菌、絮状表皮癣菌、断发毛癣菌。其中红色毛癣菌因其抵抗力强,不易控制,已成为我国当前足癣的主要致病菌。手足癣通过接触传染,在公共浴池洗澡,穿用公共拖鞋,穿用患者的鞋,袜,手套,使用公共浴巾等均易于感染本病,本病传染广泛,是由于红色毛癣菌或絮状表皮癣菌常在皮屑内形成关节孢子,它能抵抗较恶劣的环境而长期生存,并具有传染他人的能力,另外,红色毛癣菌容易引起角层增厚,侵犯毳毛,不易治愈,且易复发,再者,由于损害严重性不强,患者多无自觉症状,常不予重视,而未及时就医,因此病变常迁延不愈。手足癣极少引起严重的疾病或死亡,但可以作为细菌入侵的门户而引起细菌性蜂窝织炎。依皮损表现常可将手足癣分为1.鳞屑水疱型;2.浸渍糜烂型;3.角化过度型。三者可同时或交替出现,或以某一型为主。患者通常会出现瘙痒、水泡、角化过度、红斑、脱屑、皲裂、浸渍甚至糜烂流水等症状。Tinea manuum is the general term of tinea manuum and tinea pedis. Tinea manuum refers to a fungal infection of the superficial skin between the palm and the fingers, between the plantar and the fingers and toes. Tinea pedis is a dermatophyte infection that occurs on the soles of the feet and between the toes. Tinea pedis is a dermatosis caused by fungi invading the cuticle of hands and feet, most of which are reinfected hands by tinea pedis. In a humid and warm environment, it is conducive to the growth and reproduction of fungi, so it is very easy to occur in people in the southern region in summer. Tinea pedis is the most common disease in dermatophytosis. It is more common in adults and both men and women can suffer from it. It is prevalent all over the world. It is often exacerbated in summer and alleviated in autumn. If it is not treated thoroughly, it often lasts for many years. In the pathogenesis of athlete's foot, the lack of sebaceous glands and the humid environment caused by wearing closed shoes are the most important factors. The main pathogens include Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton flocculum, and Trichophyton trichophyton. Wherein Trichophyton rubrum has become the main pathogenic bacteria of tinea pedis in my country because of its strong resistance and difficult control. Tinea manus and pedis are transmitted through contact. Bathing in public baths, wearing public slippers, wearing patients' shoes, socks, gloves, and using public bath towels are all easy to infect the disease. The disease is widely transmitted and is caused by Trichophyton rubrum or flocculent Epidermophyton often forms joint spores in the dander, which can resist harsh environments and survive for a long time, and has the ability to infect others. In addition, Trichophyton rubrum can easily cause thickening of the horn layer, invade vellus hair, and is not easy to cure. And it is easy to relapse. Moreover, because the severity of the damage is not strong, most patients have no subjective symptoms, often ignore it, and do not seek medical treatment in time, so the lesion often persists. Tinea manus and pedis rarely cause serious illness or death, but can act as a gateway for bacterial invasion, causing bacterial cellulitis. According to the performance of skin lesions, tinea manus and pedis can often be divided into 1. Scaly blister type; 2. Dipping erosion type; 3. Hyperkeratosis type. The three can appear simultaneously or alternately, or a certain type is dominant. Patients usually present symptoms such as itching, blisters, hyperkeratosis, erythema, desquamation, chapping, maceration, and even erosion.
中医认为手足癣疾病多因脾胃湿热循经上行于手则发于癣,下注于足则发足癣,或由湿热生虫,或疫行相染所致。手足癣是难以彻底治愈的皮肤病。严重困扰人们的正常生活。现有的外用药膏均有治疗效果慢、人们不易坚持用药的缺点。公开号CN 103007121A(申请号201210507967.X)的中国专利文献公开了一种治疗手足癣的中药及制备方法,该中药组成由海桐皮9-11份、枳壳8-10份、榆钱5-7份、僵蚕3-5份、榆树皮10-12份、硫磺1-2份、马齿苋3-5份、公丁香5-7份、白芥子9-11份、艾草15-18份、土槿皮2-4份、冰片1-3份、山葡萄根10-12份、白鲜皮10-12份、枯矾4-6份、百部2-4份、雷丸9-11份、地榆3-5份、薄荷叶9-11份、柳树叶10-12份、杏仁9-11份、茯神2-4份、旱金莲8-10份和木芙蓉10-12份。公开号CN103071092A(申请号201310013222.2)的中国专利文献公开了一种治疗手足癣的中药洗剂,主要由苦参15-25份,百部15-25份,焦山楂10-20份,生山楂10-20份,食醋800-1200份,水1200-1800份组成。公开号CN 103768226A(申请号201410002203.4)的中国专利文献公开了一种治疗手足癣的中药组合物及其制备方法,组合物由下列原料组成:辣蓼50-150份,川楝子60-100份,花椒20-60份,白鲜皮40-80份,冬瓜皮120-180份,薄荷30-70份。Chinese medicine believes that tinea pedis is mostly caused by damp heat of the spleen and stomach traveling upwards along the meridian, causing tinea pedis, and placing bets on the feet, causing tinea pedis, or caused by damp heat and insects, or infection by epidemics. Tinea manus and pedis is a skin disease that is difficult to cure thoroughly. Seriously disturb people's normal life. Existing ointment for external use all has the shortcoming that curative effect is slow, and people are difficult to adhere to medication. The Chinese patent document with publication number CN 103007121A (application number 201210507967.X) discloses a traditional Chinese medicine for treating tinea manus and pedis and its preparation method. 7 parts, 3-5 parts of silkworm, 10-12 parts of elm bark, 1-2 parts of sulfur, 3-5 parts of purslane, 5-7 parts of male clove, 9-11 parts of white mustard seed, 15-18 parts of wormwood 2-4 parts of hibiscus bark, 1-3 parts of borneol, 10-12 parts of mountain grape root, 10-12 parts of white fresh skin, 4-6 parts of dry alum, 2-4 parts of baebu, 9-11 parts of Lei Wan 3-5 parts of burnet, 9-11 parts of mint leaves, 10-12 parts of willow leaves, 9-11 parts of almonds, 2-4 parts of Fushen, 8-10 parts of nasturtium and 10-12 parts of hibiscus. The Chinese patent document with publication number CN103071092A (application number 201310013222.2) discloses a traditional Chinese medicine lotion for the treatment of tinea manus and pedis, which mainly consists of 15-25 parts of Sophora flavescens, 15-25 parts of Baibu, 10-20 parts of burnt hawthorn, and 10 parts of raw hawthorn -20 parts, 800-1200 parts of vinegar, 1200-1800 parts of water. The Chinese patent document with publication number CN 103768226A (application number 201410002203.4) discloses a traditional Chinese medicine composition for treating tinea manus and pedis and its preparation method. The composition is composed of the following raw materials: Polygonum 50-150 parts, Toosendan 60-100 parts , 20-60 parts of pepper, 40-80 parts of white fresh skin, 120-180 parts of wax gourd skin, 30-70 parts of mint.
治疗手足癣的西药很多,多以抗菌止痒作用为主,但往往只能达到治表,不能根除的效果,且长期使用会对人体有一定的副作用。中医药对于此病的治疗已有一定研究基础,但能达到根治效果的配方并不多,且有些制作复杂,疗程长,成本较高,不适于患者使用。There are many Western medicines for the treatment of tinea manus and pedis, mostly based on antibacterial and antipruritic effects, but often can only achieve the effect of treating the surface, not eradication, and long-term use will have certain side effects on the human body. Traditional Chinese medicine has a certain research basis for the treatment of this disease, but there are not many formulas that can achieve a radical effect, and some of them are complicated to make, have a long course of treatment, and are expensive, so they are not suitable for patients.
发明内容Contents of the invention
为改善现有技术的不足,本发明的目的是提供一种成本较低且安全有效的手足癣中药药浴及制备方法。该中药药浴制作简单,且疗程短,疗效确切。In order to improve the deficiencies of the prior art, the object of the present invention is to provide a low-cost, safe and effective traditional Chinese medicine bath for tinea manus and pedis and a preparation method. The traditional Chinese medicinal bath is simple to make, has a short course of treatment, and has definite curative effect.
本发明的技术方案是:Technical scheme of the present invention is:
手足癣中药药浴,由下列原料药制备而成,均为重量份:蛇床子10-15,草木犀6-15,苦参9-18,黄柏6-15,鹤虱15-25,白鲜皮12-25,地肤子12-20,及己6-10,大枫子9-18,朴硝20-35,蝉蜕10-20,相思藤8-16,牡丹皮12-24,胡子七5-12,天名精6-15,枯矾5-12,九节菖蒲6-15,蜂房6-18。Tinea manus and pedis traditional Chinese medicine medicated bath is prepared from the following raw materials, all in parts by weight: Fructus Cnidii 10-15, Rhinoceros 6-15, Sophora flavescens 9-18, Phellodendron 6-15, Crane lice 15-25, Bai Xian Skin 12-25, Kochia 12-20, Jiji 6-10, Dafengzi 9-18, Park Nitrate 20-35, Cicada slough 10-20, Acacia vine 8-16, Peony bark 12-24, Huziqi 5 -12, Tianmingjing 6-15, dry alum 5-12, Jiujie calamus 6-15, hive 6-18.
优选的方案中,蛇床子11-14,草木犀8-13,苦参12-15,黄柏8-13,鹤虱17-23,白鲜皮15-22,地肤子15-17,及己7-9,大枫子12-15,朴硝25-30,蝉蜕14-16,相思藤10-14,牡丹皮16-20,胡子七7-10,天名精8-13,枯矾7-10,九节菖蒲9-12,蜂房10-14。In the preferred scheme, Cnidium 11-14, Osmanthus fragrans 8-13, Sophora flavescens 12-15, Phellodendron 8-13, Crane lice 17-23, Cortex 15-22, Kochia scoparia 15-17, and Hexa 7-9, Dafengzi 12-15, Pu Nitrate 25-30, Cicada slough 14-16, Acacia vine 10-14, Moutan bark 16-20, Huziqi 7-10, Tianmingjing 8-13, Kulum 7- 10, Jiujie Acorus 9-12, Apiary 10-14.
更加优选的,蛇床子12.5,草木犀10.5,苦参13.5,黄柏10.5,鹤虱20,白鲜皮18.5,地肤子16,及己8,大枫子13.5,朴硝27.5,蝉蜕15,相思藤12,牡丹皮18,胡子七8.5,天名精10.5,枯矾8.5,九节菖蒲10.5,蜂房12。所述中药药浴的制备方法如下:More preferably, Cnidium 12.5, Osmanthus 10.5, Sophora flavescens 13.5, Cortex Phellodendri 10.5, Crane louse 20, Baixianpi 18.5, Kochia scoparia 16, Jiji 8, Dafengzi 13.5, Pu Nitrate 27.5, Cicada slough 15, Acacia vine 12, peony bark 18, beard seven 8.5, Tianmingjing 10.5, dry alum 8.5, calamus 10.5, hive 12. The preparation method of described Chinese medicine medicated bath is as follows:
(1)将食盐置锅内文火炒热,再将牡丹皮倒入拌炒,炒至药物呈黄色取出冷却,待用;(1) Put the salt in the pot and stir-fry over low heat, then pour in the peony bark and stir-fry until the medicine turns yellow, take it out and cool it down, and set aside;
(2)将蛇床子、草木犀、苦参、黄柏、鹤虱、白藓皮、地肤子、及己、大枫子、蝉蜕、相思藤、胡子七、天名精、九节菖蒲、蜂房和步骤(1)所制得的牡丹皮放入容器内,加白酒,浸渍50-70分钟(优选60分钟);(2) Cnidium chinensis, Osmanthus fragrans, Sophora flavescens, Phellodendron chinensis, Crane lice, Moss bark, Kochia scoparia, Jiji, Dafengzi, cicada slough, Acacia vine, beard seven, Tianmingjing, Jiujie calamus, hive Put the peony cortex prepared in step (1) into the container, add white wine, and soak for 50-70 minutes (preferably 60 minutes);
(3)将朴硝和枯矾去杂质,粉成粗粉,待用;(3) Remove impurity from the nitrate and dry alum, grind it into a coarse powder, and set aside;
(4)将粉碎后的朴硝和枯矾放入砂锅中,加水浸泡,然后武火煮开,转文火煎20-40分钟(优选30分钟)后,再将步骤(2)容器中的酒与药材一起倒入砂锅中,继续煎煮后,过滤,收集滤液,药渣加水二次煎煮,武火煮开转文火煎40-60分钟(优选50分钟),过滤,合并两次滤液;(4) Put the pulverized nitrate and dried alum into a casserole, add water to soak, then boil over high heat, turn to low heat and fry for 20-40 minutes (preferably 30 minutes), then put the wine and medicinal materials in the container in step (2) Pour them into a casserole together, continue to decoct, filter, collect the filtrate, add water to the dregs of the medicine for a second decoction, boil over a strong fire and turn to a simmer for 40-60 minutes (preferably 50 minutes), filter, and combine the two filtrates;
(5)将步骤(4)所得滤液浓缩至原来体积的五分之一,加入到35-45℃左右的温水里,搅拌,即得中药药浴。(5) Concentrate the filtrate obtained in step (4) to one-fifth of its original volume, add it to warm water at about 35-45°C, and stir to obtain a traditional Chinese medicine bath.
所述的中药药浴,步骤(1)食盐量为牡丹皮重量的1-2倍(优选1.5倍)。In the traditional Chinese medicinal bath, in step (1), the amount of salt is 1-2 times (preferably 1.5 times) the weight of Moutan cortex.
所述的中药药浴,步骤(2)酒面与药材面平齐。In the traditional Chinese medicinal bath, in step (2), the surface of the wine is flush with the surface of the medicinal materials.
所述的中药药浴,步骤(4)水的用量为药材总重量的4-8倍(优选5-7倍,更加优选6倍)。In the traditional Chinese medicinal bath, the amount of water used in step (4) is 4-8 times (preferably 5-7 times, more preferably 6 times) the total weight of medicinal materials.
所述的中药药浴,步骤(4)浸泡时间为1-2小时(优选1.5小时)。In the traditional Chinese medicinal bath, the soaking time in step (4) is 1-2 hours (preferably 1.5 hours).
所述的中药药浴,步骤(4)继续煎煮的时间为50-80分钟(优选60-70分钟,更加优选65分钟)。In the traditional Chinese medicinal bath, the decocting time in step (4) is 50-80 minutes (preferably 60-70 minutes, more preferably 65 minutes).
本发明还提供了所述的中药药浴在制备治疗手足癣的药物时的应用。The invention also provides the application of the traditional Chinese medicinal bath in the preparation of medicine for treating tinea manus and pedis.
本发明所用主要中药原料的药理如下:The pharmacology of main Chinese medicine raw material used in the present invention is as follows:
蛇床子:性味:辛、苦,温;有小毒。归经:归肾经。功效:燥湿祛风,杀虫止痒,温肾壮阳。主治:用于阴痒带下,湿疹瘙痒,湿痹腰痛,肾虚阳痿,宫冷不孕。Fructus Cnidii: nature and flavor: pungent, bitter, warm; Slightly poisonous. Return through: return kidney channel. Efficacy: Dampness and expelling wind, killing insects and relieving itching, warming kidney and strengthening yang. Indications: For vaginal itching, eczema itching, damp arthralgia lumbago, kidney deficiency impotence, uterine cold infertility.
草木犀:基原:为豆科草木犀属植物细齿草木犀的全草。成分:全草含挥发油,内含香豆素。药性:《内蒙古中草药》:“味辛,性平。”功用主治:《内蒙古中草药》:“和中健胃,清热化湿,利尿。主治暑湿胸闷,口腻,口臭,赤白痢,淋病,疖疮。”Osmanthus fragrans: Base: It is the whole plant of Osmanthus spp. Ingredients: The whole plant contains volatile oil and contains coumarin. Properties: "Inner Mongolian Chinese Herbal Medicine": "Pungent in taste, flat in nature." Functions and Indications: "Inner Mongolian Chinese Herbal Medicine": "Harmony to the stomach, clearing away heat and dampness, diuretic. Indications for chest tightness due to summer heat, greasy mouth, bad breath, red and white dysentery, gonorrhea, Boils."
苦参:性味:苦,寒。归经:归心、肝、胃、大肠、膀胱经。功效:清热燥湿,杀虫,利尿。主治:用于热痢,便血,黄疸尿闭,赤白带下,阴肿阴痒,湿疹,湿疮,皮肤瘙痒,疥癣麻风,外治滴虫性阴道炎。Sophora flavescens: nature and flavor: bitter, cold. Meridians Guixin, Liver, Stomach, Large Intestine, Bladder. Efficacy: heat-clearing and damp-drying, insecticidal, diuretic. Indications: For hot dysentery, hematochezia, jaundice and urinary retention, leucorrhea, pruritus vulvae, eczema, eczema, skin itching, mange and leprosy, external treatment of trichomonas vaginitis.
黄柏:性味:苦,寒。归经:归’肾、膀胱经。功效:清热燥湿,泻火除蒸,解毒疗疮。主治:用于湿热泻痢,黄疸尿赤,带下阴痒,热淋涩痛,脚气痿蹙,骨蒸劳热,盗汗,遗精,疮疡肿毒,湿疹湿疮。盐黄柏滋阴降火。用于阴虚火旺,盗汗骨蒸。Cortex Phellodendri: Nature and flavor: bitter, cold. Return through: return 'kidney, bladder channel. Efficacy: clearing away heat and dampness, purging fire and eliminating steam, detoxifying and treating sores. Indications: For damp-heat diarrhea, jaundice, red urine, vaginal itching, hot stranguria pain, beriberi and flaccidity, bone steaming and labor-heat, night sweats, spermatorrhea, sores and swollen toxins, eczema and eczema. Salt Phellodendron nourishes yin and reduces fire. For hyperactivity of fire due to yin deficiency, night sweat and bone steam.
鹤虱:性味:苦、辛,平;有小毒。归经:归脾、胃经。功效:杀虫消积。主治:用于蛔虫病,蛲虫病,绦虫病,虫积腹痛,小儿疳积。Crane lice: nature and flavor: bitter, pungent, flat; slightly poisonous. Return through: return spleen, stomach meridian. Efficacy: killing insects and eliminating accumulation. Indications: For ascariasis, pinworm disease, tapeworm disease, worm accumulation abdominal pain, infantile malnutrition.
白鲜皮:性味:苦,寒。归经:归脾、胃、膀胱经。功效:清热燥湿,祛风解毒。主治:用于湿热疮毒,黄水淋漓,湿疹,风疹,疥癣疮癞,风湿热痹,黄疸尿赤。Radix Cortex: Nature and flavor: bitter, cold. Return through: return spleen, stomach, bladder channel. Efficacy: clearing away heat and dampness, expelling wind and detoxification. Indications: used for damp-heat sores, dripping yellow water, eczema, rubella, scabies sores, rheumatism-heat arthralgia, jaundice and red urine.
地肤子:性味:辛、苦,寒。归经:归肾、膀胱经。功效:清热利湿,祛风止痒。用于小便涩痛,阴痒带下,风疹,湿疹,皮肤瘙痒。Fructus Kochia: nature and flavor: pungent, bitter, cold. Return through: return kidney, urinary bladder channel. Efficacy: clearing heat and dampness, dispelling wind and relieving itching. It is used for astringent and painful urination, pruritus vaginal discharge, rubella, eczema, and itchy skin.
及己:基原:为金栗兰科金栗兰属植物及己的根。成分:根含有二氢焦莪术呋喃烯酮,莪焦术呋喃烯酮,银线草内酯E、F,新菖蒲酮,7-a-羟基新菖蒲酮,菖蒲酮,莪术呋喃醚酮,异莪术呋喃二烯等。药性:苦,平,有毒。功用主治:活血散瘀,祛风止痛,解毒杀虫。主治跌打损伤,骨折,经闭,风湿痹痛,疔疮疖肿,疥癣,皮肤瘙痒,毒蛇咬伤。宜忌:内服宜慎,孕妇慎服。内服过量,可出现呕吐,口渴,头痛,眼花,胸闷,手足抽搐,结膜充血,齿龈发黑,心慌心悸,神志不清等中毒症状,严重者可引起死亡。Jiji: Jiyuan: It is the root of Chestnut Orchidaceae Chrysanthemum genus Jiji. Ingredients: The root contains dihydropyrocururacetene, zedofuranone, silvergrass lactone E, F, neocoralone, 7-a-hydroxyneicocorone, calamone, curcumofuranetherketone, iso Curcumafurandiene, etc. Properties: bitter, flat, poisonous. Function cures mainly: blood circulation promoting and blood stasis dispelling, expelling wind and relieving pain, detoxifying and killing parasites. Indications for bruises, fractures, amenorrhea, rheumatic arthralgia, furuncle furuncle, scabies, skin itching, snake bites. Taboo: Oral administration should be cautious, and pregnant women should take it with caution. Oral overdose may cause vomiting, thirst, headache, dizziness, chest tightness, tetany, conjunctival hyperemia, black gums, palpitation, palpitations, confusion and other poisoning symptoms, and severe cases may cause death.
大枫子:性味:辛,热,有毒。归经:入肺,肝经。功效:祛风燥湿,攻毒杀虫。主治:麻风,外用治梅疮,疥癣,手背皲裂等症。Dafengzi: Nature and flavor: pungent, hot, poisonous. Meridian distribution: enter lung, Liver Channel. Efficacy: expelling wind and dampness, attacking poison and killing insects. Indications: leprosy, topical treatment of plum sores, scabies, chapped hands and other diseases.
朴硝:基原:为硫酸盐类芒硝族矿物芒硝或人工制品芒硝的粗制品。性味:咸、苦,寒。归经:归胃、大肠、肾经。功效:解毒消肿,泻热软坚,清火消肿。主治:用于实热积滞,腹满胀痛,大便燥结,肠痈肿痛;外治乳痈,痔疮肿痛。Pak Nitrate: Base: It is the crude product of the sulfate-like Glauber's salt mineral Glauber's salt or the artificial product. Nature and flavor: salty, bitter, cold. Meridian return: return to stomach, large intestine, kidney channel. Efficacy: detoxification and swelling, purging heat and softening hardness, clearing fire and reducing swelling. Indications: used for stagnation of excess heat, abdominal fullness and pain, dry stool, swelling and pain of intestinal abscess; external treatment of mastitis, swelling and pain of hemorrhoids.
蝉蜕:性味:甘,寒。归经:归肺、肝经。功效:疏散风热,利咽,透疹,明目退翳,解痉。主治:用于风热感冒,咽痛音哑,麻疹不透,风疹瘙痒,目赤翳障,惊风抽搐,破伤风。Cicada slough: nature and flavor: sweet, cold. Return through: return lung, liver channel. Efficacy: Dispelling wind-heat, relieving sore throat, clearing rash, improving eyesight and reducing nebula, relieving spasm. Indications: For wind-heat and cold, sore throat and hoarseness, impermeable measles, rubella and itching, convulsions and convulsions, and tetanus.
相思藤:基原:为豆科相思子属植物相思子的茎叶。成分:相思子叶中含有三萜皂苷:相思子三萜苷A、B、C、D。黄酮类:5,7,4’-三羟基黄烷苷,花旗松树-3-葡萄糖苷,甘草甜素,又含相思子内脂A,等。药性:《广西中草药》:“味甘,性平。”功用主治:清热解毒,利尿。主治感冒,咽喉肿痛,肺热咳嗽,乳痈,疮疖,肝炎。Acacia vine: base: It is the stem and leaf of Acacia acacia in the leguminous family. Ingredients: Acacia cotyledons contain triterpene saponins: Acacia triterpene glycosides A, B, C, D. Flavonoids: 5,7,4'-trihydroxyflavanoside, Douglas fir tree-3-glucoside, glycyrrhizin, and acacia lactone A, etc. Properties of medicine: "Guangxi Chinese Herbal Medicine": "Sweet in taste, flat in nature." Functions and indications: clearing heat and detoxifying, diuretic. Indications for colds, sore throat, cough due to lung heat, mastitis, boils, hepatitis.
牡丹皮(丹皮):基原:毛茛科植物牡丹的干燥根皮。性味:苦、辛,微寒。归经:归心、肝、肾经。功效:清热凉血,活血化瘀。用于热人营血,温毒发斑,吐血衄血,夜热早凉,无汗骨蒸,经闭痛经,跌扑伤痛,痈肿疮毒。Moutan bark (Paeony bark): base: the dry root bark of the ranunculaceae plant peony. Nature and flavor: bitter, pungent, slightly cold. Meridians Guixin, Liver and Kidney Channels. Efficacy: clearing heat and cooling blood, promoting blood circulation and removing blood stasis. It is used for warming the blood in people, causing spots due to warm poison, vomiting blood and epistaxis, night heat and morning coolness, bone steam without sweat, amenorrhea dysmenorrhea, tumbling pain, carbuncle and sore virus.
胡子七:基原:为毛茛科铁筷子属植物铁筷子的根及茎。成分:根含铁筷子苷。药性:苦,凉,小毒。功用主治:《陕西中草药》:“清热解毒,活血散瘀,消肿止痛。主治膀胱炎,尿道炎,疮疖肿毒,跌打损伤,劳伤。”天名精:基原:为菊科天名精属植物天名精的全草。成分:全草含倍半萜内酯:天名精内酯酮,鹤虱内酯,大叶土木香内酯,依瓦菊素,天名精内酯醇,腋生依瓦菊素,特勒内酯等。药性:苦、辛,寒。归肝、肺经。功用主治:清热化痰,解毒杀虫,破瘀止血。主治乳蛾喉痹,急慢惊风,牙痛,疔疮肿痛,痔瘘,皮肤痒疹,毒蛇咬伤,虫积,血瘕,吐血,衄血,血淋,创伤出血。 胡子七:基原:为毛茛科铁筷子属植物铁筷子的根及茎。成分:根含铁筷子苷。药性:苦,凉,小毒。功用主治:《陕西中草药》:“清热解毒,活血散瘀,消肿止痛。主治膀胱炎,尿道炎,疮疖肿毒,跌打损伤,劳伤。”Beard Seven: Base: It is the root and stem of the plant Tiechoi in the family Ranunculaceae. Ingredients: The root contains iron chopsticks glycosides. Properties of medicine: bitter, cool, slightly poisonous. Functions and Indications: "Shaanxi Chinese Herbal Medicine": "clearing heat and detoxifying, promoting blood circulation and dissipating blood stasis, reducing swelling and relieving pain. Indications for cystitis, urethritis, sores, furuncles, swollen toxins, bruises, and strains." Tianmingjing: Base: Compositae Tianmingjing is the whole herb of the plant Tianmingjing. Ingredient: Whole grass contains sesquiterpene lactones: Tianmingjing lactone ketone, Crane lactone, macrophyll inulin, evalrin, Tianmingjing lactone alcohol, axillary evalchrin, Teller Lactone, etc. Properties of medicine: bitter, pungent, cold. Return liver, lung meridian. Functions and indications: clearing away heat and resolving phlegm, detoxifying and killing parasites, breaking blood stasis and stopping bleeding. Indications for sore throat numbness of milk moth, acute and slow convulsions, toothache, furuncle swelling and pain, hemorrhoids, prurigo, venomous snake bites, worm accumulation, bloody lumps, hematemesis, epistaxis, hemorrhage, and traumatic bleeding. Beard Seven: Base: It is the root and stem of the plant Tiechoi in the family Ranunculaceae. Ingredients: The root contains iron chopsticks glycosides. Properties of medicine: bitter, cool, slightly poisonous. Functions and indications: "Shaanxi Chinese Herbal Medicine": "clearing away heat and detoxification, promoting blood circulation and dissipating blood stasis, reducing swelling and relieving pain. Indications for cystitis, urethritis, sores, furuncles, swollen toxins, bruises, and strains."
枯矾:性味:酸涩,寒。有毒。归经:入肺、脾、胃、大肠经。功效:消痰,燥湿,止泻,止血,解毒,杀虫。Dry alum: nature and flavor: sour and astringent, cold. poisonous. Meridian distribution: enter lung, spleen, stomach, large intestine meridian. Efficacy: eliminate phlegm, dry dampness, stop diarrhea, stop bleeding, detoxify, kill insects.
九节菖蒲:基原:为毛莨科银莲花属植物阿尔泰银莲花的根茎。成分:根茎含脂肪酸:棕榈酸,琥珀酸,5-羟基乙酰丙酸,十六烷酸和9,12-十八碳二烯酸,白头翁素等。药性:辛,温。归心、肝、脾经。功用主治:化痰开窍,祛风除湿,消食醒脾,解毒。主治热病神昏,癫痫,气闭耳聋,多梦健忘,风湿痹痛,胸闷脘胀,痈疽,疥癣。宜忌:阴虚阳亢、烦躁汗多、精滑者慎服。蜂房:性味:甘,平。归经:归胃经。功效:攻毒杀虫,祛风止痛。主治:用于疮疡肿毒,乳痈,瘰疬,皮肤顽癣,鹅掌风,牙痛,风湿痹痛。Nine-section calamus: base: It is the rhizome of the Altai anemone of the Ranunculaceae anemone. Ingredients: The roots contain fatty acids: palmitic acid, succinic acid, 5-hydroxylevulinic acid, hexadecanoic acid and 9,12-octadecadienoic acid, pulsatin, etc. Properties of medicine: pungent, warm. GUIXIN, liver, spleen channel. Functions and indications: resolving phlegm and resuscitating, expelling wind and dampness, eliminating food and refreshing the spleen, detoxification. Cure mainly febrile diseases, coma, epilepsy, air-occlusion deafness, dreaminess and forgetfulness, rheumatic arthralgia, chest tightness and abdominal distention, carbuncle, scabies. Precautions: Take it with caution for those with yin deficiency and yang hyperactivity, irritability, excessive sweating, and slippery skin. Honeycomb: nature and flavor: sweet, flat. Return through: return stomach meridian. Efficacy: attacking poison and killing insects, dispelling wind and relieving pain. Cure mainly: be used for sore swollen toxin, breast abscess, scrofula, intractable ringworm of the skin, typhoid fungus, toothache, rheumatic arthralgia.
本发明提供的中药药浴组方根据中医理论,结合手足癣发病机理制备而成,不仅科学有效,且制备简单,使用方便。除此之外,本发明的优良效果还表现在:The traditional Chinese medicinal bath prescription provided by the invention is prepared according to the theory of traditional Chinese medicine and combined with the pathogenesis of tinea manus and pedis, which is not only scientific and effective, but also simple to prepare and convenient to use. In addition, the excellent effect of the present invention is also manifested in:
1、本中药药浴具有清热燥湿、祛风解毒功效;1. This traditional Chinese medicinal bath has the effects of clearing away heat and dampness, expelling wind and detoxifying;
2、本组方是根据中医药原则并结合手足癣患者发病症状的特点,制备而成的,可用于治疗多种手足癣;2. This prescription is prepared according to the principles of traditional Chinese medicine and combined with the characteristics of symptoms of tinea manus and pedis patients, and can be used to treat various tinea manus and pedis;
3、本发明具有见效快、疗程短等有优点。3. The present invention has the advantages of quick effect and short course of treatment.
具体实施方式detailed description
下面结合实施例和试验例详细说明本发明的技术方案,但保护范围不限于此。The technical solution of the present invention will be described in detail below in conjunction with the examples and test examples, but the scope of protection is not limited thereto.
实施例1 手足癣中药药浴,由下列原料药制备而成:蛇床子10g,草木犀6g,苦参9g,黄柏6g,鹤虱15g,白鲜皮12g,地肤子12g,及己6g,大枫子9g,朴硝20g,蝉蜕10g,相思藤8g,牡丹皮12g,胡子七5g,天名精6g,枯矾5g,九节菖蒲6g,蜂房6g。Embodiment 1 Tinea manus and pedis traditional Chinese medicine medicine bath, is prepared from following raw materials: Fructus Cnidii 10g, Osmanthus osmanthus 6g, Sophora flavescens 9g, Cortex Phellodendri 6g, Crane louse 15g, Cortex 12g, Fructus Kochia scoparia 12g, and hexagon 6g, Dafengzi 9g, Pu Nitrate 20g, Cicada slough 10g, Acacia vine 8g, Moutan bark 12g, Huziqi 5g, Tianmingjing 6g, dried alum 5g, Jiujiechangpu 6g, hive 6g.
上述手足癣中药药浴的制备方法:The preparation method of above-mentioned tinea manus and pedis Chinese medicine medicated bath:
(1)将牡丹皮1倍重量的食盐置锅内文火炒热,再将牡丹皮倒入拌炒,炒至药物呈黄色取出冷却,待用;(1) Put the salt that is 1 times the weight of the peony cortex in a pot and stir-fry over low heat, then pour the peony cortex into the pot and stir-fry until the medicine turns yellow, take it out and cool it down, and set aside;
(2)将蛇床子、草木犀、苦参、黄柏、鹤虱、白藓皮、地肤子、及己、大枫子、蝉蜕、相思藤、胡子七、天名精、九节菖蒲、蜂房和步骤(1)所制得的牡丹皮放入容器内,加白酒,酒面与药材面平齐,浸渍50分钟;(2) Cnidium chinensis, Osmanthus fragrans, Sophora flavescens, Phellodendron chinensis, Crane lice, Moss bark, Kochia scoparia, Jiji, Dafengzi, cicada slough, Acacia vine, beard seven, Tianmingjing, Jiujie calamus, hive Put the peony bark prepared in step (1) into the container, add white wine, make the wine surface flush with the medicinal material surface, and soak for 50 minutes;
(3)将朴硝和枯矾去杂质,粉成粗粉,待用;(3) Remove impurity from the nitrate and dry alum, grind it into a coarse powder, and set aside;
(4)将粉碎后的朴硝和枯矾放入砂锅中,加药材总重量4倍的水浸泡1小时,然后武火煮开,转文火煎20分钟后,再将步骤(2)容器中的酒与药材一起倒入砂锅中,继续煎煮50分钟后,过滤,收集滤液,药渣加水二次煎煮,武火煮开转文火煎40分钟,过滤,合并两次滤液;(4) Put the pulverized nitrate and dried alum into a casserole, add water 4 times the total weight of the medicinal materials and soak for 1 hour, then boil with high heat, turn to low heat and fry for 20 minutes, then put the wine in the container in step (2) Pour it into a casserole together with the medicinal materials, continue to decoct for 50 minutes, filter, collect the filtrate, add water to the medicinal residues for a second decoction, boil over high heat and turn to simmer for 40 minutes, filter, and combine the two filtrates;
(5)将步骤(4)所得滤液浓缩至原来体积的五分之一,加入到35-45℃左右的温水里,搅拌,即得中药药浴。(5) Concentrate the filtrate obtained in step (4) to one-fifth of its original volume, add it to warm water at about 35-45°C, and stir to obtain a traditional Chinese medicine bath.
实施例2 手足癣中药药浴,由下列原料药制备而成:蛇床子15g,草木犀15g,苦参18g,黄柏15g,鹤虱25g,白鲜皮25g,地肤子20g,及己10g,大枫子18g,朴硝35g,蝉蜕20g,相思藤16g,牡丹皮24g,胡子七12g,天名精15g,枯矾12g,九节菖蒲15g,蜂房18g。Embodiment 2 Tinea manus and pedis Chinese medicinal bath, prepared from the following raw materials: Fructus Cnidii 15g, Osmanthus osmanthus 15g, Sophora flavescens 18g, Cortex Phellodendri 15g, Crane lice 25g, Cortex 25g, Fructus Kochia scoparia 20g, and 10g hemp, Dafengzi 18g, Pu Nitrate 35g, Cicada slough 20g, Acacia vine 16g, Moutan bark 24g, Huziqi 12g, Tianmingjing 15g, dry alum 12g, Jiujiechangpu 15g, hive 18g.
上述手足癣中药药浴的制备方法:The preparation method of above-mentioned tinea manus and pedis Chinese medicine medicated bath:
(1)将牡丹皮2倍重量的食盐置锅内文火炒热,再将牡丹皮倒入拌炒,炒至药物呈黄色取出冷却,待用;(1) Put 2 times the weight of the peony cortex in the pot and stir-fry over low heat, then pour the peony cortex into the pot and stir-fry until the medicine turns yellow, take it out and cool it down, and set aside;
(2)将蛇床子、草木犀、苦参、黄柏、鹤虱、白藓皮、地肤子、及己、大枫子、蝉蜕、相思藤、胡子七、天名精、九节菖蒲、蜂房和步骤(1)所制得的牡丹皮放入容器内,加白酒,酒面与药材面平齐,浸渍70分钟;(2) Cnidium chinensis, Osmanthus fragrans, Sophora flavescens, Phellodendron chinensis, Crane lice, Moss bark, Kochia scoparia, Jiji, Dafengzi, cicada slough, Acacia vine, beard seven, Tianmingjing, Jiujie calamus, hive Put the tree peony cortex prepared in step (1) into the container, add white wine, the wine surface is flush with the medicinal material surface, and soak for 70 minutes;
(3)将朴硝和枯矾去杂质,粉成粗粉,待用;(3) Remove impurity from the nitrate and dry alum, grind it into a coarse powder, and set aside;
(4)将粉碎后的朴硝和枯矾放入砂锅中,加药材总重量8倍的水浸泡2小时,然后武火煮开,转文火煎40分钟后,再将步骤(2)容器中的酒与药材一起倒入砂锅中,继续煎煮80分钟后,过滤,收集滤液,药渣加水二次煎煮,武火煮开转文火煎60分钟,过滤,合并两次滤液;(4) Put the pulverized nitrate and dried alum into a casserole, add water 8 times the total weight of the medicinal materials and soak for 2 hours, then boil with high heat, turn to low heat and fry for 40 minutes, then put the wine in the container in step (2) Pour it into a casserole together with the medicinal materials, continue to decoct for 80 minutes, filter, collect the filtrate, add water to the medicinal residues for a second decoction, boil over high heat and turn to simmer for 60 minutes, filter, and combine the two filtrates;
(5)将步骤(4)所得滤液浓缩至原来体积的五分之一,加入到35-45℃左右的温水里,搅拌,即得中药药浴。(5) Concentrate the filtrate obtained in step (4) to one-fifth of its original volume, add it to warm water at about 35-45°C, and stir to obtain a traditional Chinese medicine bath.
使用方法:水与药液的比例为25:1-30:1,将患处在药浴里浸泡20-30分钟,每天一次,7天为一疗程。How to use: The ratio of water to liquid medicine is 25:1-30:1, soak the affected part in the medicinal bath for 20-30 minutes, once a day, 7 days as a course of treatment.
典型病例:xxx,男,30岁。患有脚癣已5年,脚指红斑、脱屑、皲裂,伴有瘙痒,严重时糜烂流水,曾使用多种外用药物治疗,虽有疗效,但不久就会复发,未能根治。Typical case: xxx, male, 30 years old. Suffering from tinea pedis for 5 years, the toes are erythema, desquamation, chapped, accompanied by itching, erosion and runny water when severe, once used a variety of external drug treatment, although curative effect, will recur soon, failed to cure.
使用本实施例所得手足癣中药药浴,每次200ml,每天1次,兑入40℃左右的热水,7天为一疗程。治疗6天后,病情好转,红斑、脱皮、瘙痒等症状有所减轻,使用两个疗程后,皮肤愈合,未发现新的病变,继续使用一个疗程后,治愈,3年内未复发。Use the tinea pedis Chinese medicine medicated bath that the present embodiment gains, each 200ml, every day 1 time, add the hot water of about 40 ℃, 7 days are a course of treatment. After 6 days of treatment, the condition improved, and symptoms such as erythema, peeling, and itching were alleviated. After two courses of treatment, the skin healed and no new lesions were found. After one course of treatment, it was cured, and there was no recurrence within 3 years.
实施例3 手足癣中药药浴,由下列原料药制备而成:蛇床子11g,草木犀8g,苦参12g,黄柏8g,鹤虱17g,白鲜皮15g,地肤子15g,及己7g,大枫子12g,朴硝25g,蝉蜕14g,相思藤10g,牡丹皮16g,胡子七7g,天名精8g,枯矾7g,九节菖蒲9g,蜂房10g。Embodiment 3 Tinea manus and pedis traditional Chinese medicine medicine bath, is prepared from following raw materials: Fructus Cnidii 11g, Osmanthus osmanthus 8g, Sophora flavescens 12g, Cortex Phellodendri 8g, Crane lice 17g, Cortex 15g, Fructus Kochia 15g, and 7g, Dafengzi 12g, Pu Nitrate 25g, Cicada slough 14g, Acacia vine 10g, Moutan bark 16g, Huziqi 7g, Tianmingjing 8g, dry alum 7g, Jiujiechangpu 9g, hive 10g.
上述手足癣中药药浴的制备方法:The preparation method of above-mentioned tinea manus and pedis Chinese medicine medicated bath:
(1)将牡丹皮1.5倍重量的食盐置锅内文火炒热,再将牡丹皮倒入拌炒,炒至药物呈黄色取出冷却,待用;(1) Put 1.5 times the weight of Moutan Cortex in a pot and stir-fry over low heat, then pour the Moutan Cortex into the pot and stir-fry until the drug turns yellow, take it out and cool it, and set aside;
(2)将蛇床子、草木犀、苦参、黄柏、鹤虱、白藓皮、地肤子、及己、大枫子、蝉蜕、相思藤、胡子七、天名精、九节菖蒲、蜂房和步骤(1)所制得的牡丹皮放入容器内,加白酒,酒面与药材面平齐,浸渍60分钟;(2) Cnidium chinensis, Osmanthus fragrans, Sophora flavescens, Phellodendron chinensis, Crane lice, Moss bark, Kochia scoparia, Jiji, Dafengzi, cicada slough, Acacia vine, beard seven, Tianmingjing, Jiujie calamus, hive Put the peony bark prepared in step (1) into the container, add white wine, make the wine surface flush with the medicinal material surface, and soak for 60 minutes;
(3)将朴硝和枯矾去杂质,粉成粗粉,待用;(3) Remove impurity from the nitrate and dry alum, grind it into a coarse powder, and set aside;
(4)将粉碎后的朴硝和枯矾放入砂锅中,加药材总重量5倍的水浸泡1.5小时,然后武火煮开,转文火煎30分钟后,再将步骤(2)容器中的酒与药材一起倒入砂锅中,继续煎煮60分钟后,过滤,收集滤液,药渣加水二次煎煮,武火煮开转文火煎40分钟,过滤,合并两次滤液;(4) Put the pulverized nitrate and dried alum in a casserole, add water 5 times the total weight of the medicinal materials and soak for 1.5 hours, then boil with high heat, turn to low heat and fry for 30 minutes, then put the wine in the container in step (2) Pour it into a casserole together with the medicinal materials, continue to decoct for 60 minutes, filter, collect the filtrate, add water to the medicinal residues for a second decoction, boil over high heat and turn to simmer for 40 minutes, filter, and combine the two filtrates;
(5)将步骤(4)所得滤液浓缩至原来体积的五分之一,加入到35-45℃左右的温水里,搅拌,即得中药药浴。(5) Concentrate the filtrate obtained in step (4) to one-fifth of its original volume, add it to warm water at about 35-45°C, and stir to obtain a traditional Chinese medicine bath.
实施例4 手足癣中药药浴,由下列原料药制备而成:蛇床子14g,草木犀13g,苦参15g,黄柏13g,鹤虱23g,白鲜皮22g,地肤子17g,及己9g,大枫子15g,朴硝30g,蝉蜕16g,相思藤14g,牡丹皮20g,胡子七10g,天名精13g,枯矾10g,九节菖蒲12g,蜂房14g。Example 4 Tinea manus and pedis traditional Chinese medicinal bath, prepared from the following raw materials: Fructus Cnidii 14g, Oligocystis osmanthus 13g, Sophora flavescens 15g, Cortex Phellodendri 13g, Crane lice 23g, Cortex 22g, Kochia scoparia 17g, and 9g, Dafengzi 15g, Pu Nitrate 30g, Cicada slough 16g, Acacia vine 14g, Moutan bark 20g, Huziqi 10g, Tianmingjing 13g, dried alum 10g, Jiujiechangpu 12g, hive 14g.
上述手足癣中药药浴的制备方法:The preparation method of above-mentioned tinea manus and pedis Chinese medicine medicated bath:
(1)将牡丹皮1.5倍重量的食盐置锅内文火炒热,再将牡丹皮倒入拌炒,炒至药物呈黄色取出冷却,待用;(1) Put 1.5 times the weight of Moutan Cortex in a pot and stir-fry over low heat, then pour the Moutan Cortex into the pot and stir-fry until the drug turns yellow, take it out and cool it, and set aside;
(2)将蛇床子、草木犀、苦参、黄柏、鹤虱、白藓皮、地肤子、及己、大枫子、蝉蜕、相思藤、胡子七、天名精、九节菖蒲、蜂房和步骤(1)所制得的牡丹皮放入容器内,加白酒,酒面与药材面平齐,浸渍60分钟;(2) Cnidium chinensis, Osmanthus fragrans, Sophora flavescens, Phellodendron chinensis, Crane lice, Moss bark, Kochia scoparia, Jiji, Dafengzi, cicada slough, Acacia vine, beard seven, Tianmingjing, Jiujie calamus, hive Put the peony bark prepared in step (1) into the container, add white wine, make the wine surface flush with the medicinal material surface, and soak for 60 minutes;
(3)将朴硝和枯矾去杂质,粉成粗粉,待用;(3) Remove impurity from the nitrate and dry alum, grind it into a coarse powder, and set aside;
(4)将粉碎后的朴硝和枯矾放入砂锅中,加药材总重量7倍的水浸泡1.5小时,然后武火煮开,转文火煎30分钟后,再将步骤(2)容器中的酒与药材一起倒入砂锅中,继续煎煮70分钟后,过滤,收集滤液,药渣加水二次煎煮,武火煮开转文火煎50分钟,过滤,合并两次滤液;(4) Put the pulverized nitrate and dried alum in a casserole, add water 7 times the total weight of the medicinal materials and soak for 1.5 hours, then boil with high heat, turn to low heat and fry for 30 minutes, then put the wine in the container in step (2) Pour it into a casserole together with the medicinal materials, continue to decoct for 70 minutes, filter, collect the filtrate, add water to the medicinal residues for a second decoction, boil over a strong fire and turn to a simmer for 50 minutes, filter, and combine the filtrates twice;
(5)将步骤(4)所得滤液浓缩至原来体积的五分之一,加入到35-45℃左右的温水里,搅拌,即得中药药浴。(5) Concentrate the filtrate obtained in step (4) to one-fifth of its original volume, add it to warm water at about 35-45°C, and stir to obtain a traditional Chinese medicine bath.
使用方法:水与药液的比例为25:1-30:1,将患处在药浴里浸泡20-30分钟,每天一次,7天为一疗程。How to use: The ratio of water to liquid medicine is 25:1-30:1, soak the affected part in the medicinal bath for 20-30 minutes, once a day, 7 days as a course of treatment.
典型病例:xxx,女,18岁。患有手癣5个月,经常长水泡,部分表皮脱落,损及皮下,患病范围不断扩大,又痒又痛,曾擦过其他药膏但未见好转。Typical case: xxx, female, 18 years old. Suffering from tinea manuum for 5 months, blisters often develop, part of the epidermis falls off, and the subcutaneous area is damaged.
使用本实施例所得手足癣中药药浴,每晚睡前用温热的药水泡手30分钟,7天为一疗程。一个疗程后,表皮脱落和痒痛的不适症状减轻,范围也不再扩大,10天后,手部有新生皮长出,范围逐渐缩小,痒痛基本消失,继续使用至17天,患者自感痊愈,巩固使用至20天,根治,未复发。Use the tinea pedis Chinese medicine medicated bath of the obtained tinea pedis of present embodiment, soak hands with warm liquid medicine 30 minutes every night before going to bed, 7 days is a course of treatment. After a course of treatment, the symptoms of exfoliation and itching were relieved, and the area no longer expanded. After 10 days, new skin grew on the hands, and the area gradually narrowed. The itching and pain basically disappeared. After continuing to use for 17 days, the patient felt healed , Consolidate and use to 20 days, radical cure, no recurrence.
实施例5 手足癣中药药浴,由下列原料药制备而成:蛇床子12.5g,草木犀10.5g,苦参13.5g,黄柏10.5g,鹤虱20g,白鲜皮18.5g,地肤子16g,及己8g,大枫子13.5g,朴硝27.5g,蝉蜕15g,相思藤12g,牡丹皮18g,胡子七8.5g,天名精10.5g,枯矾8.5g,九节菖蒲10.5g,蜂房12g。Example 5 Chinese medicinal bath for tinea manus and pedis, prepared from the following raw materials: Fructus Cnidii 12.5g, Rhinoceros 10.5g, Sophora flavescens 13.5g, Cortex Phellodendri 10.5g, Crane louse 20g, Cortex 18.5g, Kochia scoparia 16g , Jiji 8g, Dafengzi 13.5g, Park Nitrate 27.5g, Cicada slough 15g, Acacia vine 12g, Moutan bark 18g, Huziqi 8.5g, Tianmingjing 10.5g, dry alum 8.5g, Jiujiechangpu 10.5g, hive 12g .
上述手足癣中药药浴的制备方法:The preparation method of above-mentioned tinea manus and pedis Chinese medicine medicated bath:
(1)将牡丹皮1.5倍重量的食盐置锅内文火炒热,再将牡丹皮倒入拌炒,炒至药物呈黄色取出冷却,待用;(1) Put 1.5 times the weight of Moutan Cortex in a pot and stir-fry over low heat, then pour the Moutan Cortex into the pot and stir-fry until the drug turns yellow, take it out and cool it, and set aside;
(2)将蛇床子、草木犀、苦参、黄柏、鹤虱、白藓皮、地肤子、及己、大枫子、蝉蜕、相思藤、胡子七、天名精、九节菖蒲、蜂房和步骤(1)所制得的牡丹皮放入容器内,加白酒,酒面与药材面平齐,浸渍60分钟;(2) Cnidium chinensis, Osmanthus fragrans, Sophora flavescens, Phellodendron chinensis, Crane lice, Moss bark, Kochia scoparia, Jiji, Dafengzi, cicada slough, Acacia vine, beard seven, Tianmingjing, Jiujie calamus, hive Put the peony bark prepared in step (1) into the container, add white wine, make the wine surface flush with the medicinal material surface, and soak for 60 minutes;
(3)将朴硝和枯矾去杂质,粉成粗粉,待用;(3) Remove impurity from the nitrate and dry alum, grind it into a coarse powder, and set aside;
(4)将粉碎后的朴硝和枯矾放入砂锅中,加药材总重量6倍的水浸泡1.5小时,然后武火煮开,转文火煎30分钟后,再将步骤(2)容器中的酒与药材一起倒入砂锅中,继续煎煮65分钟后,过滤,收集滤液,药渣加水二次煎煮,武火煮开转文火煎50分钟,过滤,合并两次滤液;(4) Put the pulverized nitrate and dried alum into a casserole, add water 6 times the total weight of the medicinal materials and soak for 1.5 hours, then boil with high heat, turn to low heat and fry for 30 minutes, then put the wine in the container in step (2) Pour it into a casserole together with the medicinal materials, continue to decoct for 65 minutes, filter, collect the filtrate, add water to the medicinal residues for a second decoction, boil over high heat and turn to simmer for 50 minutes, filter, and combine the two filtrates;
(5)将步骤(4)所得滤液浓缩至原来体积的五分之一,加入到35-45℃左右的温水里,搅拌,即得中药药浴。(5) Concentrate the filtrate obtained in step (4) to one-fifth of its original volume, add it to warm water at about 35-45°C, and stir to obtain a traditional Chinese medicine bath.
试验例1实施例5所得手足癣中药药浴的临床应用:2011年12月-2013年10月,在6所医院筛选357例患者,病程集中在6个月-5年间,临床诊断有鳞屑水疱型112例,浸渍糜烂型130例,角化过度型115例。真菌镜检为阳性。试验前一周,对该人群进行连续观察,记录症状及变化,治疗期间,患者只能使用指定药物,且生活用品与他人分开。将这些患者随机分为两组,实验组和对照组。Clinical application of Tinea manus and pedis Tinea Herbal Medicine Bath obtained in Example 5 of Test Example 1: From December 2011 to October 2013, 357 patients were screened in 6 hospitals, the course of disease was concentrated in 6 months to 5 years, and there were scaly blisters in the clinical diagnosis 112 cases of maceration-erosion type, 130 cases of maceration-erosion type, and 115 cases of hyperkeratosis type. Fungal microscopic examination was positive. One week before the test, the group was continuously observed, and the symptoms and changes were recorded. During the treatment, the patients could only use the designated drugs, and the daily necessities were separated from others. These patients were randomly divided into two groups, the experimental group and the control group.
实验组:患者257例,男139例,女118例,年龄17-56岁,平均36.8岁。使用实施例5所得产品。Experimental group: 257 patients, 139 males and 118 females, aged 17-56 years, with an average of 36.8 years old. Use the product obtained in Example 5.
对照组:患者100例,男53例,女47例,年龄17-55岁,平均36.7岁。使用达克宁、珊瑚癣净、曲安奈德益康唑乳膏等外用药。Control group: 100 patients, 53 males and 47 females, aged 17-55 years, with an average of 36.7 years old. Use of external medicines such as Dactin, Coral Tsaojing, Triamcinolone Acetonide and Econazole Cream.
疗效判定标准Efficacy criteria
(1)治愈:症状完全消失,皮肤恢复正常,真菌镜检阴性,1年内未复发;(1) Cured: the symptoms disappeared completely, the skin returned to normal, fungal microscopic examination was negative, and there was no recurrence within 1 year;
(2)显效:皮损消退﹥70%,症状消失,真菌镜检阴性,有复发,但复发时症状较轻;(2) Significantly effective: skin lesions subsided >70%, symptoms disappeared, fungal microscopic examination was negative, and there was recurrence, but the symptoms were mild at the time of recurrence;
(3)有效:皮损消退20%-70%,症状消退或减轻,真菌镜检阴性或阳性;(3) Effective: skin lesions subsided by 20%-70%, symptoms subsided or alleviated, fungal microscopic examination was negative or positive;
(4)无效:皮损消退﹤20%,症状未好转。(4) Ineffective: the skin lesions subsided <20%, and the symptoms did not improve.
服用不同药品,两组的治疗结果如下:Taking different drugs, the treatment results of the two groups are as follows:
表1:实验组患者治疗情况Table 1: Treatment status of patients in the experimental group
表2:对照组患者治疗情况Table 2: Treatment status of patients in the control group
由表1和表2可知,使用实施例5所得产品25天后,有221名患者被治愈,占85.99%,有23名患者使用后显效,占8.95%,使用后有效的8名,占3.11%,治疗无效的仅有5例,占1.95%,实验组的总有效率为98.05%,对照组的治愈率、显效率和有效分别为73.00%、8.00%和6.00%,总有效率为87.00%,可见实验组的临床治疗效果优于对照组。It can be seen from Table 1 and Table 2 that after using the product obtained in Example 5 for 25 days, 221 patients were cured, accounting for 85.99%, 23 patients were markedly effective after use, accounting for 8.95%, and 8 patients were effective after use, accounting for 3.11%. , there were only 5 cases of ineffective treatment, accounting for 1.95%. The total effective rate of the experimental group was 98.05%. The cure rate, marked rate and effective rate of the control group were 73.00%, 8.00% and 6.00%, respectively, and the total effective rate was 87.00%. , it can be seen that the clinical treatment effect of the experimental group is better than that of the control group.
本发明药方所使用的苦参、黄柏、白鲜皮清热燥湿,祛风止痒,解毒疗疮;大枫子、及己和蜂房祛风燥湿,攻毒杀虫,活血散瘀;蛇床子温阳除湿、解毒驱虫;蝉蜕和牡丹皮疏散风热,凉血解毒;天名精和枯矾解毒杀虫,破瘀止血。诸药配伍,共奏清热燥湿,解毒杀菌,祛风止痒之效。Sophora flavescens, Cortex Phellodendri, and white fresh skin used in the prescription of the present invention clear away heat and dampness, dispel wind and relieve itching, detoxify and treat sores; The bed seeds warm the yang to dehumidify, detoxify and expel parasites; cicada sloughs and tree peony bark disperse wind-heat, cool blood and detoxify; Tianmingjing and dry alum detoxify and kill insects, break blood stasis and stop bleeding. The compatibility of all medicines plays the effect of clearing away heat and dampness, detoxifying and sterilizing, dispelling wind and relieving itching.
应当指出的是,具体实施方式只是本发明比较有代表性的例子,显然本发明的技术方案不限于上述实施例,还可以有很多变形。本领域的普通技术人员,以本发明所明确公开的或根据文件的书面描述毫无异议的得到的,均应认为是本专利所要保护的范围。It should be noted that the specific implementation is only a representative example of the present invention, and obviously the technical solution of the present invention is not limited to the above-mentioned embodiments, and many variations are possible. Those of ordinary skill in the art, based on the disclosure of the present invention or obtained without objection from the written description of the document, should be considered as the protection scope of this patent.
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