CN105343794A - Drug for treating neurasthenia and preparation method thereof - Google Patents
Drug for treating neurasthenia and preparation method thereof Download PDFInfo
- Publication number
- CN105343794A CN105343794A CN201510914342.9A CN201510914342A CN105343794A CN 105343794 A CN105343794 A CN 105343794A CN 201510914342 A CN201510914342 A CN 201510914342A CN 105343794 A CN105343794 A CN 105343794A
- Authority
- CN
- China
- Prior art keywords
- grams
- gram
- radix
- semen
- impurity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a drug for treating neurasthenia and a preparation method thereof. The drug for treating the neurasthenia is mainly prepared from Chinese thorowax roots, lilies, dried rehamnnia roots, longan pulp, radix morindae officinalis, spina date seeds, licorice roots, Chinese magnoliavine fruit, fructus aurantii, ramuli et spina uncariae, colla corii asini, rhizoma anemarrhenae, cortex moutan, radix ophiopogonis, radix polygalae, radix curcumae, poria cocos, rhizoma pinelliae preparatum, semen allii tuberosi, concha margaritifera, cassia seeds, gorgon euryale seeds, Chinese caterpillar fungus, flos sophorae, radix angelicae dahuricae, fructus rosae laevigatae and mint according to a certain weight proportion. The drug for treating the neurasthenia has the functions of clearing away the heart fire, calming the nerves, tonifying deficiency, benefiting essential Qi, treating palpitation and insomnia and benefiting the heart and the spleen; when the drug is used for treating the neurasthenia, the efficacy is quick, the curative effect is good, and relapse does not occur.
Description
Technical field
The present invention relates to one and treat neurasthenic medicine and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Neurasthenia refers to due under being in nervous and pressure for a long time, occurs spirit easily excitement and mental easy tired phenomenon, often with emotion worry, irritability, sleep disorder, muscle tone pain etc.; These symptoms can not be attributed to brain, physical disease and other mental sickness.Heavy time light during symptom, fluctuate relevant with psychosocial factor, the many delays of the course of disease.The traditional Chinese medical science thinks that primary disease is many because of nervous, cruelly frightened, or ferritic is weak, and timidness due to deficiency of the heart, causes irritability and formed relevant.Because western medicine side effect is large, therefore there is great demand to effectively treating neurasthenic Chinese medicine in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the effectively neurasthenic medicine for the treatment of, thus completes the present invention.
Object of the present invention is just to provide the neurasthenic Chinese medicine composition of a kind of effectively treatment.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Radix Bupleuri, Bulbus Lilii, Radix Rehmanniae, Arillus Longan, Herba Asari, Radix Morindae Officinalis, Semen Ziziphi Spinosae, Radix Glycyrrhizae, Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Aurantii, Ramulus Uncariae Cum Uncis, Colla Corii Asini, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Ophiopogonis, Radix Polygalae, Radix Curcumae, Poria, Rhizoma Pinelliae Preparatum, Semen Allii Tuberosi, Concha Margaritifera, Semen Cassiae, Semen Euryales, Cordyceps, Flos Sophorae, the Radix Angelicae Dahuricae, Fructus Rosae Laevigatae, Herba Menthae, Semen Nelumbinis to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat neurasthenia.Wherein, select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Select Bulbus Lilii to be because its property sweet and slightly bitter taste, flat, enter the heart, lung meridian, have nourishing the lung to arrest cough, the function of clearing away heart-fire for tranquillization, control pulmonary tuberculosis chronic cough, cough and spit expectorant blood, after calentura, waste heat is unclear, and fidgets due to deficiency is palpitated with fear, staring spells, beriberi edema.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select Arillus Longan to be because its nature and flavor are sweet, temperature, enter the heart, spleen channel, have heart-spleen boosting, fill blood, the function of calming the nerves, controls virtual work thin and weak, insomnia, forgetful, palpitation with fear, severe palpitation.Select Herba Asari to be that temperature, enters lung, kidney channel, dispel the wind, cold expelling, row water because its nature and flavor are pungent, open the function of stealing, control air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Radix Morindae Officinalis to be because its property acrid-sweet flavor, temperature, enter liver, kidney channel, have kidney-replenishing, strengthening bone and muscle, the function of wind-damp dispelling, controls sexual impotence, few abdomen cold type of pain, incontinence of urine, deficiency-cold of uterus, anemofrigid-damp arthralgia, soreness of waist and knee joint.Semen Ziziphi Spinosae is selected to be that flat, enter the heart, spleen, liver, gallbladder meridian, have nourishing the liver, mind calming, calm the nerves, the function of arresting sweating, controls restlessness of asrhenia type and insomnia because its nature and flavor are sweet, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Cortex Albiziae is selected to be because its nature and flavor are sweet, flat, enter the heart, Liver Channel, have resolving depression, and blood, mind calming, the function of subduing inflammation, controls irritability, melancholy insomnia, lung abscess, carbuncle, scrofula, injured bone.Fructus Schisandrae Chinensis is selected to be that temperature, enters lung, kidney channel, astringe the lung, nourishing kidney, promote the production of body fluid, and receive antiperspirant, the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery because its nature and flavor acid.Fructus Aurantii is selected to be because its nature and flavor toil, cool, enter lung, spleen, large intestine channel, have dispelling the stagnated QI, row expectorant, the function of removing food stagnancy, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor are bitter, cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclampsia.Select Colla Corii Asini to be that enter lung, liver, kidney channel, have nourishing YIN and supplementing blood, antiabortive function, controls blood deficiency, cough due to consumptive disease because its nature and flavor are sweet flat, haematemesis, epistaxis, to have blood in stool, menoxenia, metrorrhagia, controls leakage.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle ， Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Select Radix Polygalae to be because its nature and flavor toil, temperature, enter the heart, kidney channel, have Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the function of resolving depression, controls palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, and carbuncle skin ulcer swells.Radix Curcumae is selected to be because its nature and flavor are worked hard, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of clear painful abdominal mass eliminating stagnation, control the vomiting of damp-phlegm cold drink, regurgitation, cough with asthma abundant expectoration, my diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation.Select Semen Allii Tuberosi to be that temperature, enters liver, stomach, kidney channel, have warming middle-JIAO, circulation of qi promoting because its nature and flavor are pungent, loose blood, the function of removing toxic substances, controls the thoracic obstruction, and choke every, regurgitation, haematemesis, epistaxis, hematuria, dysentery, quench one's thirst, anal fistula, proctoptosis, injury from falling down, worm, scorpion sting.Select Concha Margaritifera to be because its nature and flavor are salty, cool, enter the heart, liver two warp, have suppressing the hyperactive liver, YANG hyperactivity suppressing, arresting convulsion, the function of hemostasis, controls dizziness, tinnitus, cardiopalmus, insomnia, and demented ， Jing Epilepsy is spitted blood, epistaxis, metrorrhagia.Semen Cassiae is selected to be because its property bitter but sweet flavor, cool, enter liver, kidney channel, have liver heat removing, improving eyesight, diuretic, the function of relieving constipation, control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, liver cirrhosis abdomen, habitual constipation.Select Semen Euryales to be because its property sweet-puckery flavor, flat, enter spleen, kidney channel, have reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak, controls seminal emission, stranguria with turbid discharge, leukorrhagia, incontinence of urine, loose stool and diarrhea.Select Cordyceps to be that temperature, enters lung, kidney two warp, have tonifying deficiency, the function of beneficial vital essence because its nature and flavor are sweet, control phlegm retention and breathe heavily and cough, dyspnea due to deficiency, consumptive disease is coughed, spitting of blood, spontaneous sweating, impotence and seminal emission, soreness of waist and knee joint, and prolonged deficiency is multiple after being ill.Flos Sophorae is selected to be that cool, enter liver, large intestine channel, have heat clearing away, removing heat from blood, the function of hemostasis, controls discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis because its nature and flavor are bitter, under dysentery with red and white feces, wind heat conjunctival congestion, skin sore, and for prevention of stroke.Select the Radix Angelicae Dahuricae to be that temperature, enters lung, spleen, stomach warp, dispel the wind, dampness because its nature and flavor are pungent, detumescence, the function of pain relieving, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Fructus Rosae Laevigatae is selected to be that flat, have reinforcing the kidney and controlling nocturnal emission, the function of reducing urination and antidiarrheal, controls spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery because its nature and flavor are sour and astringent.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Semen Nelumbinis are selected to be because its property sweet-puckery flavor, flat, enter the heart, spleen, kidney channel, nourish heart, kidney tonifying, spleen reinforcing, the function of astringing intestine to stop diarrhea, control dreaminess of sleeping night, seminal emission, stranguria with turbid discharge, chronic dysentery, diarrhea of deficiency type, married woman's bleeding not during menses.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Radix Bupleuri 5-15 gram, Bulbus Lilii 15-25 gram, Radix Rehmanniae 15-25 gram, Arillus Longan 10-20, Herba Asari 2-4 gram, Radix Morindae Officinalis 15-25 gram, Semen Ziziphi Spinosae 5-15 gram, Radix Glycyrrhizae 5-10 gram, Cortex Albiziae 5-15 gram, Fructus Schisandrae Chinensis 4-7 gram, Fructus Aurantii 5-15 gram, Ramulus Uncariae Cum Uncis 15-25 gram, Colla Corii Asini 5-10 gram, Rhizoma Anemarrhenae 5-15 gram, Cortex Moutan 5-15 gram, Radix Ophiopogonis 10-20 gram, Radix Polygalae 5-15 gram, Radix Curcumae 5-15 gram, Poria 10-20 gram, Rhizoma Pinelliae Preparatum 10-15 gram, Semen Allii Tuberosi 10-20 gram, Concha Margaritifera 15-25 gram, Semen Cassiae 10-20 gram, Semen Euryales 15-25 gram, Cordyceps 5-15 gram, Flos Sophorae 5-15 gram, Radix Angelicae Dahuricae 10-15 gram, Fructus Rosae Laevigatae 10-20 gram, Herba Menthae 5-15 gram, Semen Nelumbinis 10-20 gram.
Be preferably:
Radix Bupleuri 10 grams, Bulbus Lilii 20 grams, Radix Rehmanniae 20 grams, Arillus Longan 15, Herba Asari 3 grams, Radix Morindae Officinalis 20 grams, Semen Ziziphi Spinosae 10 grams, 8 grams, Radix Glycyrrhizae, Cortex Albiziae 10 grams, Fructus Schisandrae Chinensis 6 grams, Fructus Aurantii 10 grams, Ramulus Uncariae Cum Uncis 20 grams, 8 grams, Colla Corii Asini, the Rhizoma Anemarrhenae 10 grams, Cortex Moutan 10 grams, Radix Ophiopogonis 15 grams, Radix Polygalae 10 grams, Radix Curcumae 10 grams, 15 grams, Poria, Rhizoma Pinelliae Preparatum 12 grams, Semen Allii Tuberosi 15 grams, Concha Margaritifera 20 grams, Semen Cassiae 15 grams, Semen Euryales 20 grams, Cordyceps 10 grams, 10 grams, Flos Sophorae, the Radix Angelicae Dahuricae 12 grams, Fructus Rosae Laevigatae 15 grams, Herba Menthae 10 grams, 15 grams, Semen Nelumbinis.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry;
2, Bulbus Lilii: pick decontamination, black lobe, dedust of winnowing with a dustpan is considered to be worth doing;
3, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
4, Arillus Longan: get crude drug, removing impurity;
5, Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;
6, Radix Morindae Officinalis: pick decontamination, after soaking, pumps core while hot, cutting, dry with hot water;
7, Semen Ziziphi Spinosae: bamboo basket put into by former medicine, sinks in clear water cylinder, and core is kept afloat, and shell is heavy water-bed, thorn core is pulled out, dries;
8, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
9, Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
10, Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;
11, Fructus Aurantii: removing flesh, core, edulcoration, slightly soaks, and pulls out, softens, and section, dries;
12, Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
13, Colla Corii Asini: smash use to pieces;
14, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
15, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
16, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
17, Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
18, Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
19, Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
20, Rhizoma Pinelliae Preparatum: the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
21, Semen Allii Tuberosi: get crude drug, removing undesirable root, impurity, cleans, slightly moistens, cutting, dry;
22, Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits;
23, Semen Cassiae: get clean Semen Cassiae, putting in pot to fry has fragrance to micro-, takes out, cools;
24, Semen Euryales: first rise frying in wheat bran heat release pot to cigarette, then poured into by clean Semen Euryales, stir to micro-yellow, take out, well sifted wheat bran, cools;
25, Cordyceps: removing impurity;
26, Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
27, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
28, Fructus Rosae Laevigatae: pick decontamination, cuts two lobes, slightly soaks with water, pull out, and after moistening, the residual burr of removing, digs clean hair, core, dry;
29, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
30, Semen Nelumbinis: pick most impurity, or smash, remove the peel, go the heart to use;
Two, prepare
1, the Radix Bupleuri after the process of preparing Chinese medicine, Bulbus Lilii, Radix Rehmanniae, Arillus Longan, Herba Asari, Radix Morindae Officinalis, Semen Ziziphi Spinosae, Radix Glycyrrhizae, Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Aurantii, Ramulus Uncariae Cum Uncis, Colla Corii Asini, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Ophiopogonis, Radix Polygalae, Radix Curcumae, Poria, Rhizoma Pinelliae Preparatum, Semen Allii Tuberosi, Concha Margaritifera, Semen Cassiae, Semen Euryales, Cordyceps, Flos Sophorae, the Radix Angelicae Dahuricae, Fructus Rosae Laevigatae, Herba Menthae, Semen Nelumbinis are put into decocting container, add water 8 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, namely twice decoction liquor mixing and stirring is obtained admixing medical solutions, be divided into 4 doses to take.
In prescription, Bulbus Lilii has lung moistening, clearing away heart-fire for tranquillization, and control fidgets due to deficiency palpitation with fear, the function of staring spells is monarch drug; Arillus Longan has heart-spleen boosting, fills blood, and calms the nerves, and controls insomnia, forgetful, palpitation with fear, severe palpitation; Poria has strengthening the spleen stomach function regulating, and mind tranquilizing and the heart calming controls palpitation with fear, forgetful function, the two is ministerial drug, and three taste medicines play clearing away heart-fire for tranquillization jointly, fill blood, strengthening the spleen stomach function regulating, control insomnia, forgetful, the effect of palpitation with fear, treatment neurasthenia effect is comprehensive, and with clearing away heart-fire for tranquillization, fill blood, control insomnia, palpitation with fear is that master can be effected a permanent cure, Radix Glycyrrhizae has controls weakness of the spleen and stomach, cardiopalmus with middle emergency coordinating the actions of various ingredients in a prescription, frightened carbuncle, function be adjuvant drug, Cordyceps has tonifying deficiency, and the function of beneficial vital essence, for making medicine, is take stopgap measures with all medicines of remainder.
Medicine of the present invention has clearing away heart-fire for tranquillization, tonifying deficiency, and beneficial vital essence, controls palpitation with fear, and insomnia, the function of heart-spleen boosting, is used for the treatment of neurasthenia, short treating period, instant effect, non-relapse after healing.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Taking admixing medical solutions super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept neurasthenia out-patient totally 28 examples for medical treatment.
2, diagnostic criteria
Classical symptom feels more tired after being chief complaint and requiring mental skill, often with professional achievements or deal with the decline to a certain degree of routine matter efficiency; After slight physical work, namely sense is weak and very tired, accompanies by myalgia and can not loosen.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 7 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: neurasthenia symptom disappears, body constitution recovers normal, recovery from illness;
Take a turn for the better: the mental burden that patient is excessive, nervous, weak symptom alleviates, and neurasthenia symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy neurastheniac 28 example of the present invention, effective 23 examples of result, obvious effective rate is 82.14%, and take a turn for the better 4 examples, and improvement rate is 14.29%, and invalid 1 example, total effective rate is 96.43%.
Claims (3)
1. treat a neurasthenic medicine, it is characterized in that: it is made up of the crude drug in following weight range:
Radix Bupleuri 5-15 gram, Bulbus Lilii 15-25 gram, Radix Rehmanniae 15-25 gram, Arillus Longan 10-20, Herba Asari 2-4 gram, Radix Morindae Officinalis 15-25 gram, Semen Ziziphi Spinosae 5-15 gram, Radix Glycyrrhizae 5-10 gram, Cortex Albiziae 5-15 gram, Fructus Schisandrae Chinensis 4-7 gram, Fructus Aurantii 5-15 gram, Ramulus Uncariae Cum Uncis 15-25 gram, Colla Corii Asini 5-10 gram, Rhizoma Anemarrhenae 5-15 gram, Cortex Moutan 5-15 gram, Radix Ophiopogonis 10-20 gram, Radix Polygalae 5-15 gram, Radix Curcumae 5-15 gram, Poria 10-20 gram, Rhizoma Pinelliae Preparatum 10-15 gram, Semen Allii Tuberosi 10-20 gram, Concha Margaritifera 15-25 gram, Semen Cassiae 10-20 gram, Semen Euryales 15-25 gram, Cordyceps 5-15 gram, Flos Sophorae 5-15 gram, Radix Angelicae Dahuricae 10-15 gram, Fructus Rosae Laevigatae 10-20 gram, Herba Menthae 5-15 gram, Semen Nelumbinis 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Bupleuri 10 grams, Bulbus Lilii 20 grams, Radix Rehmanniae 20 grams, Arillus Longan 15, Herba Asari 3 grams, Radix Morindae Officinalis 20 grams, Semen Ziziphi Spinosae 10 grams, 8 grams, Radix Glycyrrhizae, Cortex Albiziae 10 grams, Fructus Schisandrae Chinensis 6 grams, Fructus Aurantii 10 grams, Ramulus Uncariae Cum Uncis 20 grams, 8 grams, Colla Corii Asini, the Rhizoma Anemarrhenae 10 grams, Cortex Moutan 10 grams, Radix Ophiopogonis 15 grams, Radix Polygalae 10 grams, Radix Curcumae 10 grams, 15 grams, Poria, Rhizoma Pinelliae Preparatum 12 grams, Semen Allii Tuberosi 15 grams, Concha Margaritifera 20 grams, Semen Cassiae 15 grams, Semen Euryales 20 grams, Cordyceps 10 grams, 10 grams, Flos Sophorae, the Radix Angelicae Dahuricae 12 grams, Fructus Rosae Laevigatae 15 grams, Herba Menthae 10 grams, 15 grams, Semen Nelumbinis.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry;
(2) Bulbus Lilii: pick decontamination, black lobe, dedust of winnowing with a dustpan is considered to be worth doing;
(3) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(4) Arillus Longan: get crude drug, removing impurity;
(5) Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;
(6) Radix Morindae Officinalis: pick decontamination, after soaking, pumps core while hot, cutting, dry with hot water;
(7) Semen Ziziphi Spinosae: bamboo basket put into by former medicine, sinks in clear water cylinder, and core is kept afloat, and shell is heavy water-bed, thorn core is pulled out, dries;
(8) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
(9) Cortex Albiziae: clear water soaks to be cleaned, and pulls out, is first divided into equal greatly rectangular after moistening, then stripping and slicing or shredding, dry;
(10) Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;
(11) Fructus Aurantii: removing flesh, core, edulcoration, slightly soaks, and pulls out, softens, and section, dries;
(12) Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
(13) Colla Corii Asini: smash use to pieces;
(14) Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
(15) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(16) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(17) Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
(18) Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
(19) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
(20) Rhizoma Pinelliae Preparatum: the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(21) Semen Allii Tuberosi: get crude drug, removing undesirable root, impurity, cleans, slightly moistens, cutting, dry;
(22) Concha Margaritifera: pick decontamination, knock fragment, sieve dedust bits;
(23) Semen Cassiae: get clean Semen Cassiae, putting in pot to fry has fragrance to micro-, takes out, cools;
(24) Semen Euryales: first rise frying in wheat bran heat release pot to cigarette, then poured into by clean Semen Euryales, stir to micro-yellow, take out, well sifted wheat bran, cools;
(25) Cordyceps: removing impurity;
(26) Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
(27) Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
(28) Fructus Rosae Laevigatae: pick decontamination, cuts two lobes, slightly soaks with water, pull out, and after moistening, the residual burr of removing, digs clean hair, core, dry;
(29) Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
(30) Semen Nelumbinis: pick most impurity, or smash, remove the peel, go the heart to use;
(2) prepare
(1) Radix Bupleuri after the process of preparing Chinese medicine, Bulbus Lilii, Radix Rehmanniae, Arillus Longan, Herba Asari, Radix Morindae Officinalis, Semen Ziziphi Spinosae, Radix Glycyrrhizae, Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Aurantii, Ramulus Uncariae Cum Uncis, Colla Corii Asini, the Rhizoma Anemarrhenae, Cortex Moutan, Radix Ophiopogonis, Radix Polygalae, Radix Curcumae, Poria, Rhizoma Pinelliae Preparatum, Semen Allii Tuberosi, Concha Margaritifera, Semen Cassiae, Semen Euryales, Cordyceps, Flos Sophorae, the Radix Angelicae Dahuricae, Fructus Rosae Laevigatae, Herba Menthae, Semen Nelumbinis are put into decocting container, add water 8 times amount, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring and get final product, 4 doses are divided into take.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510914342.9A CN105343794A (en) | 2015-12-13 | 2015-12-13 | Drug for treating neurasthenia and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510914342.9A CN105343794A (en) | 2015-12-13 | 2015-12-13 | Drug for treating neurasthenia and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105343794A true CN105343794A (en) | 2016-02-24 |
Family
ID=55319953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510914342.9A Pending CN105343794A (en) | 2015-12-13 | 2015-12-13 | Drug for treating neurasthenia and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105343794A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114191289A (en) * | 2021-09-27 | 2022-03-18 | 吉林省中科医药产业集团有限公司 | Hard mass incense for relieving eye diseases |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1483446A (en) * | 2003-07-30 | 2004-03-24 | 童玉新 | Traditional Chinese medicine for treating neurosism, extracting process, formation process and use thereof |
| CN1493319A (en) * | 2002-10-28 | 2004-05-05 | 河北以岭医药研究院有限公司 | Medicine composition for treating neurasthenia |
| CN1660216A (en) * | 2004-12-07 | 2005-08-31 | 陕西康惠制药有限公司 | Oral wine agent of Chinese traditional medicine for treating neurasthenia |
| CN102961675A (en) * | 2012-10-23 | 2013-03-13 | 戴宏伟 | Traditional Chinese medicine composition for treating neurasthenia |
-
2015
- 2015-12-13 CN CN201510914342.9A patent/CN105343794A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1493319A (en) * | 2002-10-28 | 2004-05-05 | 河北以岭医药研究院有限公司 | Medicine composition for treating neurasthenia |
| CN1483446A (en) * | 2003-07-30 | 2004-03-24 | 童玉新 | Traditional Chinese medicine for treating neurosism, extracting process, formation process and use thereof |
| CN1660216A (en) * | 2004-12-07 | 2005-08-31 | 陕西康惠制药有限公司 | Oral wine agent of Chinese traditional medicine for treating neurasthenia |
| CN102961675A (en) * | 2012-10-23 | 2013-03-13 | 戴宏伟 | Traditional Chinese medicine composition for treating neurasthenia |
Non-Patent Citations (3)
| Title |
|---|
| 徐海燕: "神经衰弱的中医辨证施治体会", 《基层医学论坛》 * |
| 王学信等: "《实用慢性病治疗学》", 28 February 1994, 山东科学技术出版社 * |
| 谭敏贞等: "中药治疗神经衰弱的研究概况", 《新中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114191289A (en) * | 2021-09-27 | 2022-03-18 | 吉林省中科医药产业集团有限公司 | Hard mass incense for relieving eye diseases |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104338083A (en) | Medicament for treating irregular menstruation and preparation method thereof | |
| CN103735969B (en) | A kind of medicine for the treatment of consumptive lung disease and preparation method thereof | |
| CN103394058B (en) | Medicament for treating postpartum disease and preparation method thereof | |
| CN102772780A (en) | Medicament for treating ahypnosis and preparation method thereof | |
| CN102266532A (en) | Medicament for treating fatty liver and preparation method thereof | |
| CN102631655B (en) | Medicine for treating coronary heart disease and preparation method for medicine | |
| CN103721224B (en) | A kind of medicine for the treatment of chronic non-specific ulcerative colitis and preparation method thereof | |
| CN105343865A (en) | Medicine for treating nervous vomiting and preparation method of medicine | |
| CN102805834B (en) | Drug for curing gastritis and preparation method thereof | |
| CN103977288A (en) | Medicament for treating tourette syndrome and preparation method thereof | |
| CN103623376A (en) | Medication for treating prosopalgia and preparation method thereof | |
| CN103735916B (en) | A kind of medicine for the treatment of the nephrotic syndrome and preparation method thereof | |
| CN103405637B (en) | Drug for treating neurosis and preparation method thereof | |
| CN106110184A (en) | A kind of medicine treating fatty liver and preparation method thereof | |
| CN102805825B (en) | Drug for curing cutaneous pruritus and preparation method thereof | |
| CN105457001A (en) | Medicine for treating attention-deficit hyperactivity disorder and preparation method of medicine | |
| CN105343757A (en) | Medicine for treating abdominal distention and preparation method of medicine | |
| CN105343795A (en) | Drug for treating insomnia and preparation method thereof | |
| CN105343794A (en) | Drug for treating neurasthenia and preparation method thereof | |
| CN104056224A (en) | Medicine for treating habitual abortion and preparation method thereof | |
| CN108524888A (en) | A kind of drug and preparation method thereof for treating insomnia | |
| CN103330861B (en) | Medicine for curing cholera and preparation method thereof | |
| CN103656589B (en) | Drug for treating viral myocarditis and preparation method thereof | |
| CN103735833B (en) | A kind of medicine for the treatment of children alopecia and preparation method thereof | |
| CN106511806A (en) | Medicine for treating hysteria and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160224 |
|
| RJ01 | Rejection of invention patent application after publication |