CN105457001A - Medicine for treating attention-deficit hyperactivity disorder and preparation method of medicine - Google Patents

Medicine for treating attention-deficit hyperactivity disorder and preparation method of medicine Download PDF

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CN105457001A
CN105457001A CN201511001747.XA CN201511001747A CN105457001A CN 105457001 A CN105457001 A CN 105457001A CN 201511001747 A CN201511001747 A CN 201511001747A CN 105457001 A CN105457001 A CN 105457001A
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余勇
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余勇
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Abstract

The invention discloses a medicine for treating an attention-deficit hyperactivity disorder and a preparation method of the medicine. The medicine is mainly prepared from dragon bone, oyster, dried rehamnnia root, poria cocos, uncaria and the like at a certain weight ratio. The medicine has the functions of clearing heat, cooling blood, tranquilizing the mind, promoting intelligence, relieving convulsion and dispelling melancholy, is used for controlling the state of the attention-deficit hyperactivity disorder, and is good in curative effect and free of a side effect.

Description

A kind of medicine for the treatment of hyperkinetic syndrome and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of hyperkinetic syndrome and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Hyperkinetic syndrome is a kind of common children's behavior abnormal problem, also known as Cerebral function slight maladjustment or minimal brain dysfunction syndrome or attention deficit hyperactivity disorder.The intelligence of this kind of infant is normal or normal; but study, behavior and emotion aspect defectiveness; show as difficult concentrating; note of short duration; hyperactivity; emotion is inflammable so that affect school grade, all keeps on unpleasant terms with people in family and school, makes the head of a family and teacher feel difficulty in daily life.Because Western medicine cannot effective fast treating hyperkinetic syndrome, therefore there is great demand in the Chinese medicine of people to effective treatment hyperkinetic syndrome, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine effectively controlling the hyperkinetic syndrome state of an illness, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment hyperkinetic syndrome.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Os Draconis selected by medicine of the present invention, Concha Ostreae, Radix Rehmanniae, Poria, Ramulus Uncariae Cum Uncis, Rhizoma Acori Graminei, Radix Polygalae, succinum, Carapax et Plastrum Testudinis, Bulbus Lilii, the Radix Astragali, Cornu Cervi, the Rhizoma Pinelliae, Fructus Crataegi, Fructus Cannabis, Fructus Lycii, Fructus Ligustri Lucidi, Fructus Corni, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Glycyrrhizae, Cortex Moutan, Rhizoma Alismatis, Cortex Phellodendri, Fructus Jujubae, Fructus Mori, Semen Sesami Nigrum, Ramulus Cinnamomi, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Tritici Levis, Radix Angelicae Sinensis, Rhizoma Coptidis, Margarita, Arillus Longan crude drug carries out combination preparation, each efficacy of drugs is made by these drug regimens to produce synergism, thus effectively can treat hyperkinetic syndrome.Wherein, select Os Draconis to be because its property sweet-puckery flavor, flat, be included into the heart, liver, kidney, large intestine channel, have tranquillizing the mind by relieving convulsion, the function of arresting sweating controlling nocturnal emission with astringent drugs, control frightened Epilepsy demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, arresting seminal emission, reduce phlegm, the function of softening the hard mass, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor are bitter, cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclampsia.Rhizoma Acori Graminei is selected to be that tepor, enters the heart, liver, spleen channel, have and have one's ideas straightened out, eliminating phlegm, regulate the flow of vital energy, invigorate blood circulation because its nature and flavor are worked hard, loose wind, the function of drying, Zhi epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Select Radix Polygalae to be because its nature and flavor toil, temperature, enter the heart, kidney channel, have Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the function of resolving depression, controls palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, and carbuncle skin ulcer swells.Select succinum to be because its nature and flavor are sweet, flat, enter the heart, liver, small intestine meridian, have tranquillizing the mind by relieving convulsion, dissipating blood stasis stops blooding, and the function of relieving stranguria by diuresis, controls infantile convulsion epilepsy, palpitation with fear insomnia, stranguria with blood hematuria, urinary obstruction, and women's amenorrhea stops the stasis of blood stomachache puerperal, skin sore, traumatic injuries.Select Carapax et Plastrum Testudinis to be because its nature and flavor are salty sweet, flat, enter liver, kidney channel, have YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, the function of strong bone, controls deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spits blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.Select Bulbus Lilii to be because its property sweet and slightly bitter taste, flat, enter the heart, lung meridian, have nourishing the lung to arrest cough, the function of clearing away heart-fire for tranquillization, control pulmonary tuberculosis chronic cough, cough and spit expectorant blood, after calentura, waste heat is unclear, and fidgets due to deficiency is palpitated with fear, staring spells, beriberi edema.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating the spleen and replenishing QI, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Cornu Cervi Degelatinatum to be because its nature and flavor are salty, temperature, enter liver, kidney channel, have tonify deficiency, supporing yang function, controls insufficiency of kidney-YANG, ache of the spinal column, Deficiency and coldness of spleen and stomach, vomiting, anorexia and loose stool, deficiency-cold of uterus, bleeding not during menses.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of clear painful abdominal mass eliminating stagnation, control the vomiting of damp-phlegm cold drink, regurgitation, cough with asthma abundant expectoration, my diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation.Select Fructus Crataegi be because its nature and flavor acid sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji , mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate.Fructus Cannabis is selected to be that flat, enter spleen, stomach, large intestine channel, have and moisturize, laxation, treating stranguria, the function of invigorating blood circulation, control dryness of the intestine constipation, quench one's thirst, pyretic stranguria, migratory arthralgia, dysentery, menoxenia, scabies, tinea is insane because its nature and flavor are sweet.Fructus Lycii is selected to be that flat, have nourishing kidney, lung moistening, tonifying liver, the function of improving eyesight, controls hepatic and renal YIN deficiency, and soreness of the waist and knees is had a dizzy spell, the many tear of blurred vision, and cough due to consumptive disease, quenches one's thirst because its nature and flavor are sweet, seminal emission.Select Fructus Ligustri Lucidi to be because its property bitter but sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, the function of strong waist knee joint, controls yin asthenia generating intrinsic heat, dizzy, order flower tinnitus, soreness of the waist and knees, early whitening of beard and hair.Fructus Corni is selected to be that tepor, enters liver, kidney channel, have invigorating the liver and kidney, arresting seminal emission gas, Gu the function of collapse, controls soreness of waist and knee joint, dizzy, tinnitus, sexual impotence, and seminal emission, frequent micturition, deficiency of the liver cold and heat, incessant sweating due to debility, the heart shakes scattered pulse because its nature and flavor acid.Fructus Schisandrae Chinensis is selected to be that temperature, enters lung, kidney channel, astringe the lung, nourishing kidney, promote the production of body fluid, and receive antiperspirant, the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery because its nature and flavor acid.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, have spleen invigorating, tonifying the lung, reinforce the kidney, the function of benefit essence, controls diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease, quenches one's thirst, seminal emission, leukorrhagia, frequent micturition.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Radix Scrophulariae to be because its nature and flavor are bitter, salty, cool, enter lung, kidney channel, have YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances, control calentura excessive thirst, send out speckle, hectic fever due to YIN-deficiency consumptive fever, sleep night not peaceful, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Rhizoma Alismatis to be that cold, enter urinary bladder channel, have diuretic, eliminating dampness by diuresis, the function expelled the heat-evil, controls dysuria because its nature and flavor are sweet, edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Cortex Phellodendri is selected to be because its nature and flavor are bitter, cold, enter kidney, urinary bladder channel, have heat clearing away, dampness, pathogenic fire purging, the function of removing toxic substances, control hematodiarrhoea, have loose bowels, quench one's thirst, jaundice , flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Fructus Mori to be because its nature and flavor are sweet, cold, enter liver, kidney channel, have tonifying liver, kidney tonifying, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow the function of liquid, control hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Select Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, have invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Select Ramulus Cinnamomi to be because its property acrid-sweet flavor, temperature, enter bladder, the heart, lung meridian, have diaphoresis expelling pathogenic factors from muscles, the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enter lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting, open the function of expectorant, cure cold wind and cold, vomiting, and phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Fructus Tritici Levis is selected to be because its property sweet-salty, cool, control hectic fever due to YIN-deficiency consumptive fever, only spontaneous sweating.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Rhizoma Coptidis is selected to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, have pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, pulmonary tuberculosis, tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Margarita to be because its property sweet-salty, cold, enter the heart, Liver Channel, have tranquilizing mind, yin nourishing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., heat clearing away pendant expectorant, removing nebula improving eyesight, and the function of removing toxic substances and promoting granulation, controls palpitation with fear, palpitation with a distress feeling, epilepsy, and infantile convulsion is twitched, and dysphoria with smothery sensation is quenched one's thirst, sore throat aphtha, and the raw cataracta of order, skin infection does not close up for a long time.Select Arillus Longan to be because its nature and flavor are sweet, temperature, enter the heart, spleen channel, have heart-spleen boosting, fill blood, the function of calming the nerves, controls virtual work thin and weak, insomnia, forgetful, palpitation with fear, severe palpitation.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Os Draconis 18-20 gram, Concha Ostreae 15-25 gram, Radix Rehmanniae 8-12 gram, Poria 8-12 gram, Ramulus Uncariae Cum Uncis 8-12 gram, Rhizoma Acori Graminei 9-11 gram, Radix Polygalae 3-5 gram, succinum 1-2 gram, Carapax et Plastrum Testudinis 8-10 gram, Bulbus Lilii 8-10 gram, Radix Astragali 8-10 gram, Cornu Cervi 1-2 gram, Rhizoma Pinelliae 8-12 gram, Fructus Crataegi 8-10 gram, Fructus Cannabis 8-12 gram, Fructus Lycii 10-13 gram, Fructus Ligustri Lucidi 7-9 gram, Fructus Corni 8-10 gram, Fructus Schisandrae Chinensis 8-9 gram, Rhizoma Dioscoreae 13-17 gram, Rhizoma Anemarrhenae 6-8 gram, Radix Scrophulariae 8-10 gram, Radix Glycyrrhizae 4-6 gram, Cortex Moutan 6-8 gram, Rhizoma Alismatis 8-10 gram, Cortex Phellodendri 10-12 gram, Fructus Jujubae 10-20 gram, Fructus Mori 10-20 gram, Semen Sesami Nigrum 15-25 gram, Ramulus Cinnamomi 10-20 gram, Radix Paeoniae Alba 5-10 gram, Rhizoma Zingiberis Recens 4-6 gram, Fructus Tritici Levis 15-25 gram, Radix Angelicae Sinensis 10-20 gram, Rhizoma Coptidis 10-20 gram, Margarita 5-10 gram, Arillus Longan 5-10 gram.
Be preferably:
Os Draconis 20 grams, Concha Ostreae 20 grams, Radix Rehmanniae 10 grams, 10 grams, Poria, Ramulus Uncariae Cum Uncis 10 grams, Rhizoma Acori Graminei 10 grams, Radix Polygalae 4 grams, succinum 1.5 grams, Carapax et Plastrum Testudinis 10 grams, Bulbus Lilii 10 grams, the Radix Astragali 10 grams, 1 gram, Cornu Cervi, the Rhizoma Pinelliae 10 grams, Fructus Crataegi 10 grams, Fructus Cannabis 10 grams, Fructus Lycii 12 grams, Fructus Ligustri Lucidi 8 grams, Fructus Corni 10 grams, Fructus Schisandrae Chinensis 9 grams, Rhizoma Dioscoreae 15 grams, the Rhizoma Anemarrhenae 8 grams, Radix Scrophulariae 10 grams, 6 grams, Radix Glycyrrhizae, Cortex Moutan 8 grams, Rhizoma Alismatis 9 grams, Cortex Phellodendri 12 grams, 15 grams, Fructus Jujubae, 15 grams, Fructus Mori, Semen Sesami Nigrum 20 grams, Ramulus Cinnamomi 15 grams, the Radix Paeoniae Alba 6 grams, 5 grams, Rhizoma Zingiberis Recens, Fructus Tritici Levis 20 grams, Radix Angelicae Sinensis 15 grams, Rhizoma Coptidis 15 grams, Margarita 7 grams, Arillus Longan 8 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Os Draconis: outwash earth, smash;
2, Concha Ostreae: clean, dry, smash use;
3, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
4, Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
5, Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
6, Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
7, Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
8, succinum: pick clean impurity, the used time smashs to pieces and is ground into fine powder;
9, Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, cleans, dries, knock fritter;
10, Bulbus Lilii: pick decontamination, black lobe, ash disposal of winnowing with a dustpan is considered to be worth doing;
11, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
12, Cornu Cervi Degelatinatum: pick decontamination, hacks into fritter;
13, the Rhizoma Pinelliae: the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
14, Fructus Crataegi: pick clean impurity, sieve enucleation;
15, Fructus Cannabis: pick decontamination and residual shell, get clean core;
16, Fructus Lycii: clean impurity of winnowing with a dustpan, plucks residual stalk and the base of a fruit;
17, Fructus Ligustri Lucidi: pick decontamination, cleans, dries;
18, Fructus Corni: clean, except removal core and impurity, dry;
19, Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried; 20, Rhizoma Dioscoreae: pick clean impurity, is soaked in water to Rhizoma Dioscoreae central part is softening, pulls out and slightly dry in the air, and section is dried or dried;
21, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
22, Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;
23, Radix Glycyrrhizae: extracting liquorice sheet adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed, put in pot and fry to becoming buff with slow fire, till tack-free, taking-up cools, 100 jin, every Radix Glycyrrhizae, with refined honey 25-30 jin;
24, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
25, Rhizoma Alismatis: pick decontamination, size stepping, be soaked in water to eighty per cant thoroughly, pull out, shine cool, moistening is even to inside and outside humidity, and section, dries;
26, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
27, Fructus Jujubae: pick clean impurity, dry;
28, Fructus Mori: wash, picks decontamination, extracts long handle, dries;
29, Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
30, Ramulus Cinnamomi: slightly soak with water, pulls out, and moistening, to thoroughly, is cut into slices, dried, sieve anti-dandruff;
31, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
32, Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
33, Fructus Tritici Levis: pick decontamination, well sifted ash bits, dry after rinsing;
34, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
35, Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
36, Margarita: get Margarita and clean, wrap, boil about 2 hours altogether with bean curd and water with cloth, take out, clean, smash to pieces, adds water a little, is ground into superfine powder, dry;
37, Arillus Longan: get crude drug, removing impurity;
Two, prepare
1, by the Os Draconis of described weight, Concha Ostreae, Radix Rehmanniae, Poria, Ramulus Uncariae Cum Uncis, Rhizoma Acori Graminei, Radix Polygalae, Carapax et Plastrum Testudinis, Bulbus Lilii, the Radix Astragali, Cornu Cervi, the Rhizoma Pinelliae, Fructus Crataegi, Fructus Cannabis, Fructus Lycii, Fructus Ligustri Lucidi, Fructus Corni, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Glycyrrhizae, Cortex Moutan, Rhizoma Alismatis, Cortex Phellodendri, Fructus Jujubae, Fructus Mori, Semen Sesami Nigrum, Ramulus Cinnamomi, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Tritici Levis, Radix Angelicae Sinensis, Rhizoma Coptidis, decocting container put into by Arillus Longan, add water 8 times amount for the first time, soak after 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then within 20 minutes, filter with slow fire boiling, second time decoction liquor poured in container.
3, the mixing of twice decoction liquor is added grind as the Margarita of fine powder, succinum stir, obtain admixing medical solutions, be divided into 6 doses and take.
In prescription, Os Draconis have tranquillizing the mind by relieving convulsion, and arresting sweating controlling nocturnal emission with astringent drugs function is monarch drug; Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion, and Radix Polygalae is calmed the nerves Fructus Alpiniae Oxyphyllae, and eliminate the phlegm, both resolving depression are ministerial drug, and three taste medicines play heat clearing away suppressing the hyperactive liver jointly, Fructus Alpiniae Oxyphyllae of calming the nerves, the effect of the resolving depression that dispels the wind, and treatment hyperkinetic syndrome effect is comprehensive, and with tranquillizing and allaying excitement, resolving depression Fructus Alpiniae Oxyphyllae is main, can effect a permanent cure; Cortex Moutan heat clearing away, removing heat from blood, and blood, repercussive is adjuvant drug; Radix Glycyrrhizae has and middle emergency, lung moistening, removing toxic substances, and coordinating the actions of various ingredients in a prescription is take stopgap measures with all medicines that is left.
Medicine of the present invention has clearing away heat and cooling blood, Fructus Alpiniae Oxyphyllae of calming the nerves, and the function of relieving convulsion resolving depression, is used for the treatment of hyperkinetic syndrome, and curative effect is obvious, has no side effect.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Taking medicinal liquid super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept hyperkinetic syndrome out-patient totally 28 examples for medical treatment.
2, diagnostic criteria
Because of up to the present, there is no clear and definite pathological change as diagnosis basis, so at present still mainly with the medical history that the head of a family of infant and teacher provide, clinical manifestation characteristic, physical examination (comprising neurologic check) interview is Main Basis.Clinically, show as mental retardation, lonely obstacle, depression, coprolalia syndrome or multiple twitch syndrome, other behavior disorder more.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, 2 times on the one, each serving with 1 dose, every day early, evening respectively takes 1 time, within 20 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: hyperkinetic syndrome transference cure, recovery from illness, body constitution recovers normal;
Take a turn for the better: hyperkinetic syndrome symptom is clearly better, and attention is progressively concentrated, and personality progressively takes a turn for the better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy hyperkinetic syndrome patient 28 example of the present invention, effective 25 examples of result, obvious effective rate is 89.29%, and take a turn for the better 2 examples, and improvement rate is 7.14%, and invalid 1 example, total effective rate is 96.43%.

Claims (3)

1. treat a medicine for hyperkinetic syndrome, it is characterized in that: it is made up of the crude drug in following amount ranges:
Os Draconis 18-20 gram, Concha Ostreae 15-25 gram, Radix Rehmanniae 8-12 gram, Poria 8-12 gram, Ramulus Uncariae Cum Uncis 8-12 gram, Rhizoma Acori Graminei 9-11 gram, Radix Polygalae 3-5 gram, succinum 1-2 gram, Carapax et Plastrum Testudinis 8-10 gram, Bulbus Lilii 8-10 gram, Radix Astragali 8-10 gram, Cornu Cervi 1-2 gram, Rhizoma Pinelliae 8-12 gram, Fructus Crataegi 8-10 gram, Fructus Cannabis 8-12 gram, Fructus Lycii 10-13 gram, Fructus Ligustri Lucidi 7-9 gram, Fructus Corni 8-10 gram, Fructus Schisandrae Chinensis 8-9 gram, Rhizoma Dioscoreae 13-17 gram, Rhizoma Anemarrhenae 6-8 gram, Radix Scrophulariae 8-10 gram, Radix Glycyrrhizae 4-6 gram, Cortex Moutan 6-8 gram, Rhizoma Alismatis 8-10 gram, Cortex Phellodendri 10-12 gram, Fructus Jujubae 10-20 gram, Fructus Mori 10-20 gram, Semen Sesami Nigrum 15-25 gram, Ramulus Cinnamomi 10-20 gram, Radix Paeoniae Alba 5-10 gram, Rhizoma Zingiberis Recens 4-6 gram, Fructus Tritici Levis 15-25 gram, Radix Angelicae Sinensis 10-20 gram, Rhizoma Coptidis 10-20 gram, Margarita 5-10 gram, Arillus Longan 5-10 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Os Draconis 20 grams, Concha Ostreae 20 grams, Radix Rehmanniae 10 grams, 10 grams, Poria, Ramulus Uncariae Cum Uncis 10 grams, Rhizoma Acori Graminei 10 grams, Radix Polygalae 4 grams, succinum 1.5 grams, Carapax et Plastrum Testudinis 10 grams, Bulbus Lilii 10 grams, the Radix Astragali 10 grams, 1 gram, Cornu Cervi, the Rhizoma Pinelliae 10 grams, Fructus Crataegi 10 grams, Fructus Cannabis 10 grams, Fructus Lycii 12 grams, Fructus Ligustri Lucidi 8 grams, Fructus Corni 10 grams, Fructus Schisandrae Chinensis 9 grams, Rhizoma Dioscoreae 15 grams, the Rhizoma Anemarrhenae 8 grams, Radix Scrophulariae 10 grams, 6 grams, Radix Glycyrrhizae, Cortex Moutan 8 grams, Rhizoma Alismatis 9 grams, Cortex Phellodendri 12 grams, 15 grams, Fructus Jujubae, 15 grams, Fructus Mori, Semen Sesami Nigrum 20 grams, Ramulus Cinnamomi 15 grams, the Radix Paeoniae Alba 6 grams, 5 grams, Rhizoma Zingiberis Recens, Fructus Tritici Levis 20 grams, Radix Angelicae Sinensis 15 grams, Rhizoma Coptidis 15 grams, Margarita 7 grams, Arillus Longan 8 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Os Draconis: outwash earth, smash;
(2) Concha Ostreae: clean, dry, smash use;
(3) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(4) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;
(5) Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
(6) Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
(7) Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
(8) succinum: pick clean impurity, the used time smashs to pieces and is ground into fine powder;
(9) Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, cleans, dries, knock fritter;
(10) Bulbus Lilii: pick decontamination, black lobe, ash disposal of winnowing with a dustpan is considered to be worth doing;
(11) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
(12) Cornu Cervi Degelatinatum: pick decontamination, hacks into fritter;
(13) Rhizoma Pinelliae: the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(14) Fructus Crataegi: pick clean impurity, sieve enucleation;
(15) Fructus Cannabis: pick decontamination and residual shell, get clean core;
(16) Fructus Lycii: clean impurity of winnowing with a dustpan, plucks residual stalk and the base of a fruit;
(17) Fructus Ligustri Lucidi: pick decontamination, cleans, dries;
(18) Fructus Corni: clean, except removal core and impurity, dry;
(19) Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;
(20) Rhizoma Dioscoreae: pick clean impurity, is soaked in water to Rhizoma Dioscoreae central part is softening, pulls out and slightly dry in the air, and section is dried or dried;
(21) Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
(22) Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;
(23) Radix Glycyrrhizae: extracting liquorice sheet adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed, put in pot and fry to becoming buff with slow fire, till tack-free, taking-up cools, 100 jin, every Radix Glycyrrhizae, with refined honey 25-30 jin;
(24) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(25) Rhizoma Alismatis: pick decontamination, size stepping, be soaked in water to eighty per cant thoroughly, pull out, shine cool, moistening is even to inside and outside humidity, and section, dries;
(26) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
(27) Fructus Jujubae: pick clean impurity, dry;
(28) Fructus Mori: wash, picks decontamination, extracts long handle, dries;
(29) Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
(30) Ramulus Cinnamomi: slightly soak with water, pulls out, and moistening, to thoroughly, is cut into slices, dried, sieve anti-dandruff;
(31) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(32) Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
(33) Fructus Tritici Levis: pick decontamination, well sifted ash bits, dry after rinsing;
(34) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(35) Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
(36) Margarita: get Margarita and clean, wrap, boil about 2 hours altogether with bean curd and water with cloth, take out, clean, smash to pieces, adds water a little, is ground into superfine powder, dry;
(37) Arillus Longan: get crude drug, removing impurity;
(2) prepare
(1) by the Os Draconis of described weight, Concha Ostreae, Radix Rehmanniae, Poria, Ramulus Uncariae Cum Uncis, Rhizoma Acori Graminei, Radix Polygalae, Carapax et Plastrum Testudinis, Bulbus Lilii, the Radix Astragali, Cornu Cervi, the Rhizoma Pinelliae, Fructus Crataegi, Fructus Cannabis, Fructus Lycii, Fructus Ligustri Lucidi, Fructus Corni, Fructus Schisandrae Chinensis, Rhizoma Dioscoreae, the Rhizoma Anemarrhenae, Radix Scrophulariae, Radix Glycyrrhizae, Cortex Moutan, Rhizoma Alismatis, Cortex Phellodendri, Fructus Jujubae, Fructus Mori, Semen Sesami Nigrum, Ramulus Cinnamomi, the Radix Paeoniae Alba, Rhizoma Zingiberis Recens, Fructus Tritici Levis, Radix Angelicae Sinensis, Rhizoma Coptidis, decocting container put into by Arillus Longan, add water 8 times amount for the first time, soak after 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container,
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then within 20 minutes, filter with slow fire boiling, pours in container by second time decoction liquor;
(3) mixing of twice decoction liquor is added grind as the Margarita of fine powder, succinum stir, obtain admixing medical solutions, be divided into 6 doses and take.
CN201511001747.XA 2015-12-29 2015-12-29 Medicine for treating attention-deficit hyperactivity disorder and preparation method of medicine Withdrawn CN105457001A (en)

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CN107050266A (en) * 2017-06-21 2017-08-18 李贵荣 It is a kind of to treat medicine of spontaneous perspiration and preparation method thereof

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CN106511741A (en) * 2016-12-16 2017-03-22 蒋大涵 Medicine for treating infantile hyperactivity and preparation method thereof
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