CN103735833B - A kind of medicine for the treatment of children alopecia and preparation method thereof - Google Patents

A kind of medicine for the treatment of children alopecia and preparation method thereof Download PDF

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CN103735833B
CN103735833B CN201410040513.5A CN201410040513A CN103735833B CN 103735833 B CN103735833 B CN 103735833B CN 201410040513 A CN201410040513 A CN 201410040513A CN 103735833 B CN103735833 B CN 103735833B
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radix
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CN103735833A (en
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王心聚
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Hangzhou Yuanyi Health Technology Co ltd
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Abstract

The invention discloses a kind of medicine for the treatment of children alopecia and preparation method thereof, it is mainly prepared from according to a certain weight ratio by medicines such as Radix Ophiopogonis, the Radix Angelicae Dahuricae, Radix Rehmanniae, Herba Ecliptae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Flos Carthami, Fructus Psoraleaes, medicine of the present invention has the kidney invigorating tonifying YIN, the function of nourishing blood to suppress the hyperactive liver, be used for the treatment of children alopecia instant effect, good effect, has no side effect.

Description

A kind of medicine for the treatment of children alopecia and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of children alopecia and preparation method thereof, belong to the field of Chinese medicines.
Technical background
The common alopecia of children's's phase is posteriority alopecia, mostly due to frightened, frightened or nutrition is unbalanced, thus causes that organism metabolism is not normal, endocrine regulation, causes alopecia.Because current Western medicine effectively cannot treat children alopecia, therefore there is great demand in the Chinese medicine of people to rapid, effective treatment children alopecia, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment children alopecia, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment children alopecia.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Radix Ophiopogonis, the Radix Angelicae Dahuricae, Radix Rehmanniae, Herba Ecliptae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Flos Carthami, Fructus Psoraleae, Fructus Ligustri Lucidi, the Radix Astragali, Fructus Jujubae, Cacumen Platycladi, Folium Mori, Radix Scrophulariae, Radix Codonopsis, Colla Corii Asini, Arillus Longan, Herba Cistanches, Rhizoma Polygoni Cuspidati, Cortex Phellodendri, Semen Cuscutae, the Radix Linderae, Radix Polygoni Multiflori Preparata, Fructus Crataegi, Endothelium Corneum Gigeriae Galli, Fructus Citri Sarcodactylis, Radix Salviae Miltiorrhizae, Cortex Moutan, Radix Glycyrrhizae, Fructus Mori, Semen Sesami Nigrum, Placenta Hominis medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat children alopecia.Wherein select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Select the Radix Angelicae Dahuricae to be that temperature, enters lung, spleen, stomach warp, dispel the wind, dampness because its nature and flavor are pungent, detumescence, the function of pain relieving, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select Herba Ecliptae to be because its nature and flavor picric acid, cool, enter liver, kidney channel, have removing heat from blood, hemostasis, the kidney invigorating, the function of tonifying YIN, controls haematemesis, hemoptysis, epistaxis, and hematuria is had blood in stool, dysentery, and knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, dysentery, pudendum pruritus due to damp pathogen.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Fructus Psoraleae is selected to be that temperature, enter kidney channel, have the function of reinforcing the kidney and supporting YANG, control cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and coughed, external curing vitiligo because its nature and flavor are pungent.Select Fructus Ligustri Lucidi to be because its property bitter but sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, the function of strong waist knee joint, controls yin asthenia generating intrinsic heat, dizzy, order flower tinnitus, soreness of the waist and knees, early whitening of beard and hair.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating the spleen and replenishing QI, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Cacumen Platycladi to be because its nature and flavor are pained, cold, enter the heart, liver, large intestine channel, have removing heat from blood, hemostasis, wind-damp dispelling, the function of loose toxic swelling, controls haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, cough, erysipelas, and mumps is scalded.Select Folium Mori to be because its property bitter but sweet flavor, cold, enter lung, Liver Channel, have expelling wind and clearing away heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens generates heat, headache, and conjunctival congestion is thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Select Radix Scrophulariae to be because its nature and flavor are bitter, salty, cool, enter lung, kidney channel, have YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances, control calentura excessive thirst, send out speckle, hectic fever due to YIN-deficiency consumptive fever, sleep night not peaceful, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Select Colla Corii Asini to be that flat, enter lung, liver, kidney channel, have nourishing YIN and supplementing blood, antiabortive function, controls blood deficiency, cough due to consumptive disease because its nature and flavor are sweet, haematemesis, epistaxis, to have blood in stool, menoxenia, metrorrhagia, vaginal bleeding during pregnancy.Select Arillus Longan to be because its nature and flavor are sweet, temperature, enter the heart, spleen channel, have heart-spleen boosting, fill blood, the function of calming the nerves, controls virtual work thin and weak, insomnia, forgetful, palpitation with fear, severe palpitation.Select Herba Cistanches to be that temperature, enters kidney, large intestine channel, have the kidney invigorating because the sweet acid of its nature and flavor is salty, benefit essence, moisturize, the function of bowel relieving, controls impotence in male, infertilitas feminis, leukorrhagia, metrorrhagia, chills and pain of the waist and kness, blood depletion constipation.Select Rhizoma Polygoni Cuspidati to be because its nature and flavor are bitter, flat, dispel the wind, dampness removing, removing blood stasis with potent drugs, the function of stimulating the menstrual flow, dispelling the wind and dampness pathogens bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis , lumps in the chest and abdomen, anal fistula hematochezia, injury from falling down, scalds, malignant boil tinea disease.Cortex Phellodendri is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Semen Cuscutae to be because its property acrid-sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, beneficial marrow, the function of improving eyesight, controls soreness of waist and knee joint, and seminal emission, quench one's thirst, dripping urination, order is dark.Select the Radix Linderae to be that temperature, enters spleen, lung, kidney, urinary bladder channel, have pleasant, dissipating depression of QI, cold expelling, the function of pain relieving, control QI rising in reverse order chest and abdomen swelling and pain because its nature and flavor are pungent, dyspepsia is discontented with, and food is told in regurgitation, colic of cold type, beriberi, frequent micturition.Radix Polygoni Multiflori is selected to be that tepor, enters liver, kidney channel, have tonifying liver, kidney tonifying, nourish blood, the function of dispeling the wind because its property bitter but sweet flavor is puckery, control hepatic and renal YIN deficiency, sending out must be early white, and blood deficiency is dizzy, and waist knee joint is weak, and muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Select Fructus Crataegi be because its nature and flavor acid sweet, tepor, enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function, controls meat Ji , mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's breast food stagnate.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, control stagnant, the function of strengthening the spleen and stomach, control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Selecting Fructus Citri Sarcodactylis, different name Fructus Citri Sarcodactylis, Bergamot, is that temperature, enter liver, stomach warp, regulate the flow of vital energy, the function of reducing phlegm, treats for stomachache, and coerces swollen, vomiting, dysphagic, phlegm retention cough with asthma, and can relieve the effect of alcohol because the arduous acid of its nature and flavor.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have activating blood circulation and dissipating phlegm, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina pectoris, menoxenia, dysmenorrhea, amenorrhea, and metrorrhagia leukorrhagia , mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Fructus Mori to be because its nature and flavor are sweet, cold, enter liver, kidney channel, have tonifying liver, kidney tonifying, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., grow the function of liquid, control hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Select Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, have invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Select Placenta Hominis to be because its property sweet-salty, temperature, enters lung, liver, kidney channel, has QI invigorating, nourish blood, and the function of benefit essence, controls deficient, weakness and emaciation, consumptive fever hectic fever due to YIN-deficiency, cough with asthma, spitting of blood, night sweat, seminal emission, sexual impotence, and women's vim and vigour are not enough, infertile or newborn few.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following dosage
Radix Ophiopogonis 6-15 gram of Radix Angelicae Dahuricae 5-15 gram Radix Rehmanniae 8-20 gram
Herba Ecliptae 6-16 gram of Radix Angelicae Sinensis 8-18 gram of Radix Paeoniae Alba 8-18 gram
Flos Carthami 4-12 gram of Fructus Psoraleae 6-15 gram of Fructus Ligustri Lucidi 8-20 gram
Radix Astragali 6-16 gram of Fructus Jujubae 2-4 piece of Cacumen Platycladi 8-15 gram
Folium Mori 6-18 gram of Radix Scrophulariae 4-12 gram of Radix Codonopsis 5-12 gram
Colla Corii Asini 4-10 gram of Arillus Longan 5-10 gram of Herba Cistanches 8-16 gram
Rhizoma Polygoni Cuspidati 5-12 gram of Cortex Phellodendri 6-12 gram of Semen Cuscutae 5-15 gram
Radix Linderae 5-12 restrains Radix Polygoni Multiflori 4-12 Keshan short, bristly hair or beard 6-15 gram
Endothelium Corneum Gigeriae Galli 6-15 gram of Fructus Citri Sarcodactylis 5-12 gram of Radix Salviae Miltiorrhizae 6-15 gram
Cortex Moutan 4-12 gram of Radix Glycyrrhizae 2-8 gram of Fructus Mori 5-12 gram
Semen Sesami Nigrum 8-20 gram of Placenta Hominis 8-18 gram
Be preferably
8 grams of Radixs Angelicae Dahuricae Radix Ophiopogonis, 8 grams of Radix Rehmanniae 10 grams
Herba Ecliptae 12 grams of Radix Angelicae Sinensis 10 grams of Radix Paeoniae Albas 10 grams
Flos Carthami 5 grams of Fructus Psoraleaes 10 grams of Fructus Ligustri Lucidi 10 grams
The Radix Astragali 8 grams of Fructus Jujubaes 3 pieces of Cacumen Platycladis 10 grams
Folium Mori 10 grams of Radix Scrophulariaes 8 grams of Radix Codonopsis 10 grams
Colla Corii Asini 8 grams of Arillus Longans 8 grams of Herba Cistanches 10 grams
Rhizoma Polygoni Cuspidati 8 grams of Cortex Phellodendris 8 grams of Semen Cuscutae 8 grams
The Radix Polygoni Multiflori 8 Keshan short, bristly hair or beard 9 grams restrained by the Radix Linderae 8
Endothelium Corneum Gigeriae Galli 10 grams of Fructus Citri Sarcodactyliss 10 grams of Radix Salviae Miltiorrhizaes 8 grams
10 grams, Cortex Moutan 8 grams of Radix Glycyrrhizaes 3 grams of Fructus Moris
Semen Sesami Nigrum 10 grams of Placenta Hominiss 10 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
2, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
3, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
4, Herba Ecliptae: pick clean impurity, removing undesirable root, clean vexed, cutting is dried;
5, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
6, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
7, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
8, Fructus Psoraleae: clean impurity of winnowing with a dustpan, cleans, dries;
9, Fructus Ligustri Lucidi: pick decontamination, cleans, dries;
10, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
11, Fructus Jujubae: pick clean impurity, dry;
12, Cacumen Platycladi: pick clean impurity, rubs broken destemming, well sifted ash bits;
13, Folium Mori: pick decontamination, rub with the hands broken, winnow with a dustpan destemming, and sieve removes spare;
14, Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;
15, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
16, Colla Corii Asini: smash use to pieces;
17, Arillus Longan: get crude drug, removing impurity;
18, Herba Cistanches: pick clean impurity, clear water soaks, and changes water every day 1-2 times, and as being salty Herba Cistanches, bubble is salinity to the greatest extent, runs through, longitudinal section, dries;
19, Rhizoma Polygoni Cuspidati: adopt after, smooth file, dries;
20, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
21, Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
22, the Radix Linderae: pick decontamination, separately size bar, saturating with blister, changing water according to noting season, preventing smelly, pulling section out in time, sieve dedust bits;
23, Radix Polygoni Multiflori Preparata: get clean Radix Polygoni Multiflori pieces, puts in non iron container, adds Semen sojae atricolor and suitable quantity of water with boiling 3-4 hours, a vexed night, during to appearance black, inner brown, takes out, removes bean dregs, shine to half-dried, admixed by remaining liquid, run through, cut sheet, dry;
24, Fructus Crataegi: pick clean impurity, sieve enucleation;
25, Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;
26, Fructus Citri Sarcodactylis: pick decontamination, after water spray profit, chopping, dries;
27, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
28, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
29, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
30, Fructus Mori: wash, picks decontamination, extracts long handle, dries;
31, Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
32, Placenta Hominis: with fresh Placenta Hominis, anyhow cut open blood vessel, washes drift totally repeatedly with water.
Two, prepare
1, the Radix Ophiopogonis of described weight, the Radix Angelicae Dahuricae, Radix Rehmanniae, Herba Ecliptae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Flos Carthami, Fructus Psoraleae, Fructus Ligustri Lucidi, the Radix Astragali, Fructus Jujubae, Cacumen Platycladi, Folium Mori, Radix Scrophulariae, Radix Codonopsis, Colla Corii Asini, Arillus Longan, Herba Cistanches, Rhizoma Polygoni Cuspidati, Cortex Phellodendri, Semen Cuscutae, the Radix Linderae, Radix Polygoni Multiflori Preparata, Fructus Crataegi, Endothelium Corneum Gigeriae Galli, Fructus Citri Sarcodactylis, Radix Salviae Miltiorrhizae, Cortex Moutan, Radix Glycyrrhizae, Fructus Mori, Semen Sesami Nigrum, Placenta Hominis are decocted with water twice, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor.
2, add water the medicinal residues after first time filtration 4 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor.
3, merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 4 doses to take.
Medicine of the present invention has the function of the kidney invigorating tonifying YIN, nourishing blood to suppress the hyperactive liver, is used for the treatment of children alopecia instant effect, good effect.Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept for medical treatment outpatient service 3-12 year patient totally 100 example.
2, diagnostic criteria
The reason that child loses hair has a lot, and the symptom that often kind of situation has them different comprises:
(1) one piece one piece, place head being sent out bald, rubicundity, easy scaling (sometimes, the place lost hair is black), this illustrates that baby may grow tinea capitis, and it is that child loses hair modal reason that this Infectious fungi infects.
(2) physiological damage.Such as little girl, because pricking the too tight or boiling hot hair dyeing of pigtail or place with a long pigtail, causes traction alopecia.
(3) child always likes to can't help around hair or hair-plucking, may cause hair brokenly one piece one piece come off, this is called " trichotillomania ".
(4) place of child's alopecia not only circle but also light, a hair does not all have, and that may be alopecia areata, the immune system attack of child hair follicle is described, thoroughly slow down the speed of growth of hair.Although such alopecia is all occur in a certain local usually, the hair of whole body also may be had influence on.
(5) some disease, such as hypothyroidism (i.e. thyroid disorders) or hypopituitarism (i.e. pituitary gland under-activity), also to cause on person who is very popular with children alopecia everywhere.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, 3-4 year each 1/3 dose, 5-8 year each 1/2 dose, 9-12 year each 1 dose, sooner or later each once, within 30 days, be a course for the treatment of, take 4 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: children alopecia symptom is fully recovered, recover normal.
Take a turn for the better: children alopecia symptom alleviates, and progressively takes a turn for the better.
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy children alopecia patient 100 example of the present invention, effective 81 examples of result, obvious effective rate is 81%, and take a turn for the better 8 examples, and improvement rate is 8%, and invalid 11 examples, total effective rate is 89%.

Claims (3)

1. treat a medicine for children alopecia, it is characterized in that: it is made up of the crude drug in following weight range:
Radix Ophiopogonis 6-15 gram of Radix Angelicae Dahuricae 5-15 gram Radix Rehmanniae 8-20 gram
Herba Ecliptae 6-16 gram of Radix Angelicae Sinensis 8-18 gram of Radix Paeoniae Alba 8-18 gram
Flos Carthami 4-12 gram of Fructus Psoraleae 6-15 gram of Fructus Ligustri Lucidi 8-20 gram
Radix Astragali 6-16 gram of Fructus Jujubae 2-4 piece of Cacumen Platycladi 8-15 gram
Folium Mori 6-18 gram of Radix Scrophulariae 4-12 gram of Radix Codonopsis 5-12 gram
Colla Corii Asini 4-10 gram of Arillus Longan 5-10 gram of Herba Cistanches 8-16 gram
Rhizoma Polygoni Cuspidati 5-12 gram of Cortex Phellodendri 6-12 gram of Semen Cuscutae 5-15 gram
Radix Linderae 5-12 restrains Radix Polygoni Multiflori 4-12 Keshan short, bristly hair or beard 6-15 gram
Endothelium Corneum Gigeriae Galli 6-15 gram of Fructus Citri Sarcodactylis 5-12 gram of Radix Salviae Miltiorrhizae 6-15 gram
Cortex Moutan 4-12 gram of Radix Glycyrrhizae 2-8 gram of Fructus Mori 5-12 gram
Semen Sesami Nigrum 8-20 gram of Placenta Hominis 8-18 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
8 grams of Radixs Angelicae Dahuricae Radix Ophiopogonis, 8 grams of Radix Rehmanniae 10 grams
Herba Ecliptae 12 grams of Radix Angelicae Sinensis 10 grams of Radix Paeoniae Albas 10 grams
Flos Carthami 5 grams of Fructus Psoraleaes 10 grams of Fructus Ligustri Lucidi 10 grams
The Radix Astragali 8 grams of Fructus Jujubaes 3 pieces of Cacumen Platycladis 10 grams
Folium Mori 10 grams of Radix Scrophulariaes 8 grams of Radix Codonopsis 10 grams
Colla Corii Asini 8 grams of Arillus Longans 8 grams of Herba Cistanches 10 grams
Rhizoma Polygoni Cuspidati 8 grams of Cortex Phellodendris 8 grams of Semen Cuscutae 8 grams
The Radix Polygoni Multiflori 8 Keshan short, bristly hair or beard 9 grams restrained by the Radix Linderae 8
Endothelium Corneum Gigeriae Galli 10 grams of Fructus Citri Sarcodactyliss 10 grams of Radix Salviae Miltiorrhizaes 8 grams
10 grams, Cortex Moutan 8 grams of Radix Glycyrrhizaes 3 grams of Fructus Moris
Semen Sesami Nigrum 10 grams of Placenta Hominiss 10 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(2) Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
(3) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(4) Herba Ecliptae: pick clean impurity, removing undesirable root, clean vexed, cutting is dried;
(5) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(6) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(7) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(8) Fructus Psoraleae: clean impurity of winnowing with a dustpan, cleans, dries;
(9) Fructus Ligustri Lucidi: pick decontamination, cleans, dries;
(10) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
(11) Fructus Jujubae: pick clean impurity, dry;
(12) Cacumen Platycladi: pick clean impurity, rubs broken destemming, well sifted ash bits;
(13) Folium Mori: pick decontamination, rub with the hands broken, winnow with a dustpan destemming, and sieve removes spare;
(14) Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;
(15) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(16) Colla Corii Asini: smash use to pieces;
(17) Arillus Longan: get crude drug, removing impurity;
(18) Herba Cistanches: pick clean impurity, clear water soaks, and changes water every day 1-2 times, and as being salty Herba Cistanches, bubble is salinity to the greatest extent, runs through, longitudinal section, dries;
(19) Rhizoma Polygoni Cuspidati: adopt after, smooth file, dries;
(20) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
(21) Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
(22) Radix Linderae: pick decontamination, separately size bar, saturating with blister, changing water according to noting season, preventing smelly, pulling section out in time, sieve dedust bits;
(23) Radix Polygoni Multiflori Preparata: get clean Radix Polygoni Multiflori pieces, puts in non iron container, adds Semen sojae atricolor and suitable quantity of water with boiling 3-4 hours, a vexed night, during to appearance black, inner brown, takes out, removes bean dregs, shine to half-dried, admixed by remaining liquid, run through, cut sheet, dry;
(24) Fructus Crataegi: pick clean impurity, sieve enucleation;
(25) Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;
(26) Fructus Citri Sarcodactylis: pick decontamination, after water spray profit, chopping, dries;
(27) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(28) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(29) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
(30) Fructus Mori: wash, picks decontamination, extracts long handle, dries;
(31) Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
(32) Placenta Hominis: with fresh Placenta Hominis, anyhow cut open blood vessel, washes drift totally repeatedly with water;
(2) prepare
(1) Radix Ophiopogonis of described weight, the Radix Angelicae Dahuricae, Radix Rehmanniae, Herba Ecliptae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Flos Carthami, Fructus Psoraleae, Fructus Ligustri Lucidi, the Radix Astragali, Fructus Jujubae, Cacumen Platycladi, Folium Mori, Radix Scrophulariae, Radix Codonopsis, Colla Corii Asini, Arillus Longan, Herba Cistanches, Rhizoma Polygoni Cuspidati, Cortex Phellodendri, Semen Cuscutae, the Radix Linderae, Radix Polygoni Multiflori Preparata, Fructus Crataegi, Endothelium Corneum Gigeriae Galli, Fructus Citri Sarcodactylis, Radix Salviae Miltiorrhizae, Cortex Moutan, Radix Glycyrrhizae, Fructus Mori, Semen Sesami Nigrum, Placenta Hominis are decocted with water twice, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor;
(2) add water the medicinal residues after first time filtration 4 times amount, and intense fire decocts boiling, then uses slow fire boiling 20 minutes, filters and to obtain second time decoction liquor;
(3) merge twice decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes, is divided into 4 doses to take.
CN201410040513.5A 2014-01-28 2014-01-28 A kind of medicine for the treatment of children alopecia and preparation method thereof Active CN103735833B (en)

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