CN102631638B - Medicine for treating phthisis and preparation method for medicine - Google Patents

Medicine for treating phthisis and preparation method for medicine Download PDF

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CN102631638B
CN102631638B CN201210095829.5A CN201210095829A CN102631638B CN 102631638 B CN102631638 B CN 102631638B CN 201210095829 A CN201210095829 A CN 201210095829A CN 102631638 B CN102631638 B CN 102631638B
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CN102631638A (en
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郑其田
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Abstract

The invention discloses a medicine for treating phthisis and a preparation method for the medicine. The medicine is mainly prepared by coastal glehnia roots, coltsfoot flower, rhizoma atractylodis macrocephalae, donkeyhide glue beads, sienna, cortex moutan, physochlaina macrophylla, radix rehmanniae, radix notoginseng, rhizoma polygonati, American ginseng, human placenta, radix stemonae, radix curcumae, honeysuckle, gentiana, ophiopogon roots, rhizoma anemarrhenae, tuckahoe, radix bupleuri, cassia twig and safflower carthamus by weight. The medicine has functions of nourishing the kidney and the lung, nourishing yin to lessen fire, replenishing qi to invigorate the spleen, reinforcing the vital energy and consolidating the constitution and preventing phlegm from forming and stopping coughing, is used for treating the phthisis, is short in treatment course and free of toxic and side effects, and takes effect fast, and the phthisis does not have a relapse after curing.

Description

A kind of phthisical medicine and preparation method thereof for the treatment of
Technical field
The present invention relates to a kind of phthisical medicine and preparation method thereof for the treatment of, belong to the field of Chinese medicines.
Technical background
Tuberculosis is the chronic infectious disease being caused by tubercule bacillus, can involve a plurality of organs of whole body, but the most common with pulmonary tuberculosis.Primary disease pathological characteristic is tubercle and caseous necrosis, easily forms cavity.Be chronic process clinically, minority can suddenly play morbidity more.Often there are the respiratory system performances such as low grade fever, the General Symptoms such as weak and cough, spitting of blood.Can fall ill throughout the year, the teenager of 15 years old to 35 years old is age peak year occurred frequently lungy.4~8 weeks incubation periods.Wherein 80% occur in pulmonary, other positions (neck lymph, meninges, peritoneum, intestinal, skin, skeleton) also can secondary infection.Mainly, through respiratory infectious, the source of infection is the lunger of contact discharge of bacteria.After liberation people's living standard improves constantly, and tuberculosis is basic controlling, but in recent years, along with the propagation of environmental pollution and acquired immune deficiency syndrome (AIDS), tuberculosis is staged a comeback again, and sickness rate rises to some extent.At present, western medicine pulmonary tuberculosis poor effect, and have more side effect, therefore, there is very large demand to the phthisical Chinese medicine of rapid, effective treatment in people.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the phthisical Chinese medicine of effective treatment, thereby has completed the present invention.
Object of the present invention is just to provide a kind ofly can effectively treat phthisical composition of medicine.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects Radix Glehniae, Flos Farfarae, the Rhizoma Atractylodis Macrocephalae, Colla Corii Asini bead, Haematitum, Cortex Moutan, Radix Physochlainae, Radix Rubiae, Cortex Mori, Radix Rehmanniae, Radix Notoginseng, Rhizoma Polygoni Cuspidati, Fructus Perillae, Herba Lycopi, Cortex Lycii, Bulbus Lilii, Concha Ostreae, Herba Violae, Rhizoma Polygonati, Radix Panacis Quinquefolii, Placenta Hominis, the Radix Stemonae, Radix Curcumae, Flos Lonicerae, Radix Gentianae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Poria, Radix Bupleuri, Ramulus Cinnamomi, Flos Carthami medicine to combine, make each efficacy of drugs produce synergism these drug regimens, thus can the phthisical recurrence of fast treating.Wherein select Radix Glehniae to be because its nature and flavor sweetness and bitterness is light, cool, enter lung, spleen channel, have nourishing YIN and clearing away lung-heat, the function of expelling phlegm for arresting cough, controls lung-heat type cough, chronic consumptive disease chronic cough, and the moon is hindered dry pharynx, thirsty.Select Flos Farfarae to be because its nature and flavor are pungent, temperature, enters lung meridian, has nourishing the lung to keep the adverse QI downward, and the function of the antitussive that reduces phlegm is controlled cough with dyspnea and panted, sore throat.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature, enters spleen, stomach warp, has spleen reinforcing, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.Select Colla Corii Asini to be because its nature and flavor are sweet flat, enter lung, liver, kidney channel, have nourishing YIN and supplementing blood, antiabortive function, controls blood deficiency, and cough due to consumptive disease, is had blood in stool at haematemesis, epistaxis, menoxenia, and metrorrhagia, controls leakage.Select Haematitum to be because its nature and flavor are bitter, sweet, be slightly cold, return liver, stomach, heart channel, have suppressing the hyperactive liver and subsiding YANG, important city sending down the abnormal ascending QI, the function of cooling blood for hemostasis, controls head front dizzy, and cardiopalmus is demented, infantile convulsion, vomiting, eructation, cough and asthma, spits blood, epistaxis, metrorrhagia, has blood in stool, hematuria.Select Cortex Moutan to be because its nature and flavor are arduous, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, sends out speckle , Jing Epilepsy, and tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Radix Physochlainae (withered Siberian cocklebur) to be because the sweet micro-bitterness of its nature and flavor is hot in nature, poisonous, have tonify deficiency, warming middle-JIAO, calms the nerves, and the function of Dingchuan is controlled work weak, diarrhea due to deficiency-cold, insomnia, palpitation and being susceptible to fright, cough phlegm dyspnea, night sweat spontaneous perspiration.Select Radix Rubiae to be because its nature and flavor are bitter, cold, there is cooling blood for hemostasis, the function that blood stasis dispelling stimulates the menstrual flow, controls haematemesis, epistaxis, metrorrhagia, traumatic hemorrhage, stasis blocking amenorrhea, arthralgia, tumbling and swelling.Select Cortex Mori to be because its nature and flavor are sweet, cold, enter lung, spleen channel, there is eliminating pathogen from the lung for relieving asthma, the function of line water detumescence, controls dyspnea and cough due to lung-heat, spits blood, edema, beriberi, dysuria.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid, controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, sends out speckle dermexanthesis.Selecting Radix Notoginseng is that temperature, enters liver, stomach, large intestine channel, has hemostasis because of its property sweet and slightly bitter taste, dissipating blood stasis, and detumescence, the function of analgesic therapy, controls haematemesis, hemoptysis, epistaxis, has blood in stool, dysentery, metrorrhagia, mass in the abdomen, puerperal blood faints, retention of lochia, falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.Select Rhizoma Polygoni Cuspidati to be because its nature and flavor are bitter, flat, dispel the wind, dampness removing, removing blood stasis with potent drugs, the function of stimulating the menstrual flow, dispelling the wind and dampness pathogens bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis , lumps in the chest and abdomen, anal fistula hematochezia, injury from falling down, scalds malignant boil tinea disease.Select Fructus Perillae to be because its nature and flavor are pungent, temperature, enters lung, large intestine channel, has the therapeutic method to keep the adverse QI flowing downwards, expectorant, and lung moistening, the function of wide intestinal, controls cough with dyspnea, phlegm dyspnea, the stagnation of QI, constipation.Selecting Herba Lycopi is that tepor, enters liver, spleen channel, invigorates blood circulation because of its nature and flavor toil, and the function of row water, controls amenorrhea , mass in the abdomen, the stagnant stomachache of the stasis of blood in puerperal, body and face edema, injury from falling down, incised wound, carbuncle.Select Cortex Lycii to be because its nature and flavor are sweet, cold, enter lung, liver, kidney channel, there is heat clearing away, the function of removing heat from blood, controls asthenia hectic fever night sweat, and lung-heat cough with asthma is spitted blood, epistaxis, stranguria with blood, quenches one's thirst, hypertension, carbuncle, malignant boil.Select Bulbus Lilii to be because its property sweet and slightly bitter taste is flat, enter the heart, lung meridian, have nourishing the lung to arrest cough, the function of clearing away heart-fire for tranquillization, controls pulmonary tuberculosis chronic cough, cough and spit expectorant blood, and after calentura, waste heat is unclear, fidgets due to deficiency palpitation with fear, staring spells, beriberi edema.Select Concha Ostreae to be because its nature and flavor are salty and bitter, cool, enter liver, kidney channel, have yin fluid astringing, YANG hyperactivity suppressing, hidroschesis, the function of arresting seminal emission, Zhi Jing Epilepsy, dizzy, spontaneous perspiration, night sweat, seminal emission, stranguria with turbid discharge, metrorrhagia, leukorrhagia, scrofula, goiter.Select Herba Violae to be because its nature and flavor are bitter, cold, enter the heart, Liver Channel, there is clearing away heat-damp and promoting diuresis, the function of removing toxic substances and promoting subsidence of swelling, controls furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Select Rhizoma Polygonati to be because its nature and flavor are sweet flat, enter spleen, lung, kidney channel, have invigorating the spleen and replenishing QI, profit cardiopulmonary, the function of bone and muscle strengthening, controls deficient cold and heat, pulmonary tuberculosis hemoptysis, the empty lack of appetite of body after being ill, muscles and bones is weak, rheumatalgia, wind favus disease.Select Radix Panacis Quinquefolii to be because its property sweet and slightly bitter taste is cool, enter the heart, lung, kidney three warps, useful lung yin, clear asthenic fire, the function of promoting the production of body fluid to quench thirst, controls deficiency of the lung chronic cough, loses blood, dry throat and mouth, deficiency-heat is tired tired.Selecting Placenta Hominis is because its property sweet-salty, and temperature, enters lung, liver, kidney channel, has QI invigorating, nourish blood, the function of benefit essence, control deficient, weakness and emaciation, consumptive fever hectic fever due to YIN-deficiency, cough with asthma, spitting of blood, night sweat, seminal emission, sexual impotence, women's vim and vigour are not enough, infertile or newborn few.Selecting the Radix Stemonae is that tepor, enters lung meridian, has gentle lung qi because of its nature and flavor sweetness and bitterness, cough-relieving, and the function of parasite killing, controls cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.Select Radix Curcumae to be because its nature and flavor are arduous, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, controls all pains of breast abdomen side of body rib, loses the heart demented, calentura coma, spits blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Flos Lonicerae to be because its nature and flavor are sweet, cold, enter lung, stomach warp, there is heat clearing away, the function of removing toxic substances, controls epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Select Radix Gentianae to be because its nature and flavor are bitter, cold, enter liver, gallbladder meridian, there is eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat , Jing Epilepsy, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.Select Radix Ophiopogonis to be because its property sweet and slightly bitter taste is cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid, controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, thirsty clearly, calentura Tianjin wound, dry mouth and throat, constipation.Select the Rhizoma Anemarrhenae to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, there is nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Poria to be because its property slightly sweet flavor is flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, controls dysuria, edema distension, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Select Radix Bupleuri to be because its nature and flavor are bitter, cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain, and bitter taste is deaf, headache and dizziness, malaria, diarrhea proctoptosis, menoxenia, uterine prolapse.Selecting Ramulus Cinnamomi is that temperature, enters bladder, the heart, lung meridian, has diaphoresis expelling pathogenic factors from muscles because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Select Flos Carthami to be because its nature and flavor are pungent, temperature, enters the heart, Liver Channel, has promoting blood circulation to restore menstrual flow, and the function of blood stasis removing pain relieving is controlled amenorrhea , mass in the abdomen, difficult labour, and stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight:
Radix Glehniae 5-15 gram of Flos Farfarae 5-15 gram of Rhizoma Atractylodis Macrocephalae 5-15 gram
Colla Corii Asini bead 11-14 gram of Haematitum 10-20 gram of Cortex Moutan 10-20 gram
Radix Physochlainae 11-14 gram of Radix Rubiae 5-15 gram of Cortex Mori 10-20 gram
Radix Rehmanniae 11-14 gram of Radix Notoginseng 10-20 gram of Rhizoma Polygoni Cuspidati 15-25 gram
Fructus Perillae 10-20 gram of Herba Lycopi 5-15 gram of Cortex Lycii 15-25 gram
Bulbus Lilii 6-10 gram of Concha Ostreae 5-15 gram of Herba Violae 6-10 gram
Rhizoma Polygonati 10-20 gram of Radix Panacis Quinquefolii 5-15 gram of Placenta Hominis 15-25 gram
Radix Stemonae 6-10 gram of Radix Curcumae 5-15 gram of Flos Lonicerae 15-25 gram
Radix Gentianae 6-10 gram of Radix Ophiopogonis 6-10 gram of Rhizoma Anemarrhenae 6-10 gram
Poria 15-25 gram of Radix Bupleuri 15-25 gram of Ramulus Cinnamomi 15-25 gram
Flos Carthami 15-25 gram
Preferable amount is:
10 grams of 10 grams of Rhizoma Atractylodis Macrocephalaes of 10 grams of Flos Farfaraees of Radix Glehniae
15 grams of 15 grams of Cortex Moutans of 12 grams of Haematitums of Colla Corii Asini bead
15 grams of 10 grams of Cortex Mori of 12 grams of Radix Rubiaes of Radix Physochlainae
20 grams of 15 grams of Rhizoma Polygoni Cuspidati of 12 grams of Radix Notoginseng of Radix Rehmanniae
20 grams of 10 grams of Cortex Lycii of 15 grams of Herba Lycopi of Fructus Perillae
8 grams of 10 grams of Herba Violaes of 8 grams of Concha Ostreaes of Bulbus Lilii
20 grams of 10 grams of Placenta Hominiss of 15 grams of Radix Panacis Quinquefoliis of Rhizoma Polygonati
20 grams of 10 grams of Flos Loniceraes of 8 grams of Radix Curcumaes of the Radix Stemonae
8 grams of 8 grams of Rhizoma Anemarrhenaes of 8 grams of Radix Ophiopogonis of Radix Gentianae
20 grams of 20 grams of Ramulus Cinnamomi of 15 grams of Radix Bupleuri of Poria
15 grams, Flos Carthami
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Glehniae: choose decontamination, remove stem foot, water is slightly washed, pulls out, slightly moistens, and cutting, dries;
2, Flos Farfarae: choose stubble, sandstone, clod;
3, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
4, Colla Corii Asini bead: first Pulvis concha Mactrae is put to heating in pot, put into the dice shape fritter Colla Corii Asini cutting in the time of extremely easily, fry to heaving into round bead shape, be yellow-white, take out immediately, sieve removes Pulvis concha Mactrae, cools;
5, Haematitum: get crude drug, remove impurity, cleaning, drying, break into fragment or be ground into coarse powder;
6, Cortex Moutan: choose decontamination, remove core, clean, run through, section, dries;
7, Radix Physochlainae: root is cleaned, removed rough bark, after boiling altogether with appropriate Radix Glycyrrhizae, Radix Ophiopogonis, Fructus Gardeniae, crystal sugar, dry use;
8, Radix Rubiae: remove impurity, clean, run through, cut sheet or section, dry, sieve removes chip;
9, Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
10, Radix Rehmanniae: remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
11, Radix Notoginseng: choose most impurity, smash to pieces, grind or run through section into powder and dry;
12, Rhizoma Polygoni Cuspidati: adopt after, smooth file, dries;
13, Fructus Perillae: the dedust of winnowing with a dustpan bits, clean, dry;
14, Herba Lycopi: choose decontamination, remove undesirable root, water spray is profit slightly, and cutting is dried;
15, Cortex Lycii: choose decontamination and core, slightly wash, dry, cutting;
16, Bulbus Lilii: choose decontamination, black lobe, the dedust of winnowing with a dustpan bits;
17, Concha Ostreae: clean, dry, pulverize use;
18, Herba Violae: choose clean impurity, water washes away earth, cutting is dried;
19, Rhizoma Polygonati: clean earth, slightly profit, cuts into slices, and dries;
20, Radix Panacis Quinquefolii: former medicinal clear water spray tide, cover wet cloth, Xia Qiu profit 2 days, Winter-Spring profit 3 days, takes out section, dries;
21, Placenta Hominis: with fresh Placenta Hominis, anyhow cut open blood vessel, water is repeatedly washed and floated totally;
22, the Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;
23, Radix Curcumae: be soaked in water, clean, pull out to shine and dry in the air, run through, section, dries;
24, Flos Lonicerae: sieve removes silt, chooses clean impurity;
25, Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
26, Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;
27, the Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, softens, and section is dried;
28, Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
29, Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through rear timely section, dry immediately;
30, Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
31, Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
Two, preparation
The Radix Glehniae of described weight, Flos Farfarae, the Rhizoma Atractylodis Macrocephalae, Colla Corii Asini bead, Haematitum, Cortex Moutan, Radix Physochlainae, Radix Rubiae, Cortex Mori, Radix Rehmanniae, Radix Notoginseng, Rhizoma Polygoni Cuspidati, Fructus Perillae, Herba Lycopi, Cortex Lycii, Bulbus Lilii, Concha Ostreae, Herba Violae, Rhizoma Polygonati, Radix Panacis Quinquefolii, Placenta Hominis, the Radix Stemonae, Radix Curcumae, Flos Lonicerae, Radix Gentianae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Poria, Radix Bupleuri, Ramulus Cinnamomi, Flos Carthami medicine are added to 4 times of water gagings to be soaked, soak after 90 minutes, intense fire decocts boiling 20 minutes, use again slow fire boiling 20 minutes, filter, decoction liquor is poured in container for the first time.
Add for the second time 2 times of amounts of water, intense fire decocts boiling 20 minutes, then uses slow fire boiling 10 minutes, obtains decoction liquor for the second time.
Twice decoction liquor mixed, then simmer in water 10 minutes, decoction liquor is filtered, be divided into 4 doses and take.
Medicine of the present invention has the kidney invigorating lung benefiting, nourishing YIN to lower pathogenic fire, replenishing QI to invigorate the spleen, element culturing fixed folder, preventing phlegm from forming and stopping coughing.Function, be used for the treatment of pulmonary tuberculosis, short treating period, instant effect, non-relapse after healing, have no side effect.
The specific embodiment
By test example, further set forth below the beneficial effect of medicine of the present invention, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get 20 of rabbit, male and female dual-purpose, body weight 2.0-2.2kg, divides two groups, and 10 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is administration by gavage administration, every day three times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The phthisical clinical observation material of [test example 2] Drug therapy of the present invention:
1, physical data
Accept out-patient's totally 100 examples for medical treatment, its early, mid-term patient's 80 examples, patients with terminal 20 examples.
2, diagnostic criteria
Pulmonary tuberculosis early, mid-term symptom be tired easily weak obvious with early morning and afternoon, but evening can be excited, sometimes irritated insomnia.Lose weight and can not find other reason, stomach poor appetite moves back, food and tasteless.There is chronic cough or with expectoration, morning, sputum mixed with blood or spitting of blood, appearred in dry cough.Hectic fever in the afternoon, afternoon or evening low grade fever, move back after midnight to the greatest extent, as tidewater, having rises has.Sleep hyperhidrosis is also accompanied feeling of fatigue, sometimes repeatedly occurs.Chest pain, uncomfortable in chestly can, with heating, likely suffer from pleuritis.Women occur menoxenia as through amount minimizing, delay or amenorrhea; Male patient especially adolescence is easily passed out semen.
Pulmonary tuberculosis symptom in late period is respiratory failure, occurs gradual dyspnea, and even cyanosis, when complicated with pneumothorax or a large amount of hydrothorax, has the dyspnea of hurried appearance, and cough is more than, and hemoptysis is serious.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, early, mid-term patient each serving with 1 dose, every day is early, respectively take 1 evening, within 20 days, is a course for the treatment of, takes continuously 3 courses for the treatment of.Patients with terminal is each serving with 1 dose, and every day, early, middle and late respectively clothes 1 time, 30 days was a course for the treatment of, took continuously 3 courses for the treatment of.
4, efficacy assessment standard
Effective: pulmonary tuberculosis transference cure, it is normal that body constitution is recovered, and observes half a year without recidivist;
Take a turn for the better: pulmonary tuberculosis shape is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
Figure 710262DEST_PATH_IMAGE001
In above-mentioned treatment, by Drug therapy lunger's 100 examples of the present invention, its early, mid-term patient's 80 examples, effective 75 examples of result, obvious effective rate is 93.75%, 4 examples that take a turn for the better, improvement rate is 5%, invalid 1 example, total effective rate is 98.75%.Patients with terminal 20 examples, effective 14 examples of result, obvious effective rate is 70%, 5 examples that take a turn for the better, improvement rate is 25%, invalid 1 example, total effective rate is 95%.

Claims (3)

1. treat a phthisical medicine, it is characterized in that: it is to be made by the crude drug in following weight range:
Radix Glehniae 5-15 gram of Flos Farfarae 5-15 gram of Rhizoma Atractylodis Macrocephalae 5-15 gram
Colla Corii Asini bead 11-14 gram of Haematitum 10-20 gram of Cortex Moutan 10-20 gram
Radix Physochlainae 11-14 gram of Radix Rubiae 5-15 gram of Cortex Mori 10-20 gram
Radix Rehmanniae 11-14 gram of Radix Notoginseng 10-20 gram of Rhizoma Polygoni Cuspidati 15-25 gram
Fructus Perillae 10-20 gram of Herba Lycopi 5-15 gram of Cortex Lycii 15-25 gram
Bulbus Lilii 6-10 gram of Concha Ostreae 5-15 gram of Herba Violae 6-10 gram
Rhizoma Polygonati 10-20 gram of Radix Panacis Quinquefolii 5-15 gram of Placenta Hominis 15-25 gram
Radix Stemonae 6-10 gram of Radix Curcumae 5-15 gram of Flos Lonicerae 15-25 gram
Radix Gentianae 6-10 gram of Radix Ophiopogonis 6-10 gram of Rhizoma Anemarrhenae 6-10 gram
Poria 15-25 gram of Radix Bupleuri 15-25 gram of Ramulus Cinnamomi 15-25 gram
Flos Carthami 15-25 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
10 grams of 10 grams of Rhizoma Atractylodis Macrocephalaes of 10 grams of Flos Farfaraees of Radix Glehniae
15 grams of 15 grams of Cortex Moutans of 12 grams of Haematitums of Colla Corii Asini bead
15 grams of 10 grams of Cortex Mori of 12 grams of Radix Rubiaes of Radix Physochlainae
20 grams of 15 grams of Rhizoma Polygoni Cuspidati of 12 grams of Radix Notoginseng of Radix Rehmanniae
20 grams of 10 grams of Cortex Lycii of 15 grams of Herba Lycopi of Fructus Perillae
8 grams of 10 grams of Herba Violaes of 8 grams of Concha Ostreaes of Bulbus Lilii
20 grams of 10 grams of Placenta Hominiss of 15 grams of Radix Panacis Quinquefoliis of Rhizoma Polygonati
20 grams of 10 grams of Flos Loniceraes of 8 grams of Radix Curcumaes of the Radix Stemonae
8 grams of 8 grams of Rhizoma Anemarrhenaes of 8 grams of Radix Ophiopogonis of Radix Gentianae
20 grams of 20 grams of Ramulus Cinnamomi of 15 grams of Radix Bupleuri of Poria
15 grams, Flos Carthami.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Glehniae: choose decontamination, remove stem foot, water is slightly washed, pulls out, slightly moistens, and cutting, dries;
(2) Flos Farfarae: choose stubble, sandstone, clod;
(3) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out after bubble, run through, section, dries;
(4) Colla Corii Asini bead: first Pulvis concha Mactrae is put to heating in pot, put into the dice shape fritter Colla Corii Asini cutting in the time of extremely easily, fry to heaving into round bead shape, be yellow-white, take out immediately, sieve removes Pulvis concha Mactrae, cools;
(5) Haematitum: get crude drug, remove impurity, cleaning, drying, break into fragment or be ground into coarse powder;
(6) Cortex Moutan: choose decontamination, remove core, clean, run through, section, dries;
(7) Radix Physochlainae: root is cleaned, removed rough bark, after boiling altogether with appropriate Radix Glycyrrhizae, Radix Ophiopogonis, Fructus Gardeniae, crystal sugar, dry use;
(8) Radix Rubiae: remove impurity, clean, run through, cut sheet or section, dry, sieve removes chip;
(9) Cortex Mori: brush away ash bits, clean, run through rear shredding, dry;
(10) Radix Rehmanniae: remove impurity, clean, slightly profit, cuts sheet, dry, and sieve removes chip;
(11) Radix Notoginseng: choose most impurity, smash to pieces, grind or run through section into powder and dry;
(12) Rhizoma Polygoni Cuspidati: adopt after, smooth file, dries;
(13) Fructus Perillae: the dedust of winnowing with a dustpan bits, clean, dry;
(14) Herba Lycopi: choose decontamination, remove undesirable root, water spray is profit slightly, and cutting is dried;
(15) Cortex Lycii: choose decontamination and core, slightly wash, dry, cutting;
(16) Bulbus Lilii: choose decontamination, black lobe, the dedust of winnowing with a dustpan bits;
(17) Concha Ostreae: clean, dry, pulverize use;
(18) Herba Violae: choose clean impurity, water washes away earth, cutting is dried;
(19) Rhizoma Polygonati: clean earth, slightly profit, cuts into slices, and dries;
(20) Radix Panacis Quinquefolii: former medicinal clear water spray tide, cover wet cloth, Xia Qiu profit 2 days, Winter-Spring profit 3 days, takes out section, dries;
(21) Placenta Hominis: with fresh Placenta Hominis, anyhow cut open blood vessel, water is repeatedly washed and floated totally;
(22) Radix Stemonae: choose clean impurity, remove fibrous root, clean, run through rear cutting, dry;
(23) Radix Curcumae: be soaked in water, clean, pull out to shine and dry in the air, run through, section, dries;
(24) Flos Lonicerae: sieve removes silt, chooses clean impurity;
(25) Radix Gentianae: choose decontamination, remove residual stem, clean, run through rear cutting, dry;
(26) Radix Ophiopogonis: choose clean impurity, be soaked in water, pull out, pump the heart after running through, then clean and dry;
(27) Rhizoma Anemarrhenae: choose clean impurity, water hits to be washed, and pulls out, softens, and section is dried;
(28) Poria: be soaked in water, clean, pull out, vexed after, cut into slices, dry;
(29) Radix Bupleuri: choose decontamination, remove residual stem, clean silt, pull out, run through rear timely section, dry immediately;
(30) Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
(31) Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;
(2) preparation
The Radix Glehniae of described weight, Flos Farfarae, the Rhizoma Atractylodis Macrocephalae, Colla Corii Asini bead, Haematitum, Cortex Moutan, Radix Physochlainae, Radix Rubiae, Cortex Mori, Radix Rehmanniae, Radix Notoginseng, Rhizoma Polygoni Cuspidati, Fructus Perillae, Herba Lycopi, Cortex Lycii, Bulbus Lilii, Concha Ostreae, Herba Violae, Rhizoma Polygonati, Radix Panacis Quinquefolii, Placenta Hominis, the Radix Stemonae, Radix Curcumae, Flos Lonicerae, Radix Gentianae, Radix Ophiopogonis, the Rhizoma Anemarrhenae, Poria, Radix Bupleuri, Ramulus Cinnamomi, Flos Carthami medicine are added to 4 times of water gagings to be soaked, soak after 90 minutes, intense fire decocts boiling 20 minutes, use again slow fire boiling 20 minutes, filter, decoction liquor is poured in container for the first time;
Add for the second time 2 times of amounts of water, intense fire decocts boiling 20 minutes, then uses slow fire boiling 10 minutes, obtains decoction liquor for the second time;
Twice decoction liquor mixed, then simmer in water 10 minutes, decoction liquor is filtered, be divided into 4 doses and take.
CN201210095829.5A 2012-04-05 2012-04-05 Medicine for treating phthisis and preparation method for medicine Expired - Fee Related CN102631638B (en)

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