CN104056224A - Medicine for treating habitual abortion and preparation method thereof - Google Patents

Medicine for treating habitual abortion and preparation method thereof Download PDF

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Publication number
CN104056224A
CN104056224A CN201410285222.2A CN201410285222A CN104056224A CN 104056224 A CN104056224 A CN 104056224A CN 201410285222 A CN201410285222 A CN 201410285222A CN 104056224 A CN104056224 A CN 104056224A
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fructus
herba
rhizoma
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卢文华
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卢文华
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Abstract

The invention discloses a medicine for treating habitual abortion and a preparation method thereof. The medicine for treating habitual abortion is prepared by catnip, black soybean, ladybell root, villous amomum fruit, epimeddium, ligustrum lucidum, dark plum, tarragon, sharpleaf galangal fruit and morinda officinalis according to certain weight ratio. The medicine has the functions of warming and nourishing liver and kidney, stopping bleeding and invigorating spleen, nourishing yin and preventing miscarriage, and can be used for treating habitual abortion with fast effectiveness, good curative effect and no recurrence.

Description

A kind of medicine for the treatment of habitual abortion and preparation method thereof
Technical field
The present invention relates to a kind of medicine that is used for the treatment of habitual abortion and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Habitual abortion is continuous 3 the above persons of spontaneous abortion, and each miscarriage often occurs in same gestation month.The traditional Chinese medical science is called " habitual abortion ".The reason of habitual abortion mostly and the factor such as anemia of pregnant woman's luteal phase defect, hypothyroidism, inborn uterus deformity, congenital uterine anomalies, intrauterine adhesion, hysteromyoma, chromosomal abnormality closely related.Habitual late abortion is often for due to internal cervical orifice relaxes.How, due to dilatation and curettage or the caused cervical orifice damage of cervix dilating, minority may belong to congenital abnormal development.This type of patient is after midtrimester of pregnancy, and because amniotic fluid increases, fetus grows up, and internal pressure of uterine cavity power increases, and foetal sac can be outstanding from cervix uteri internal orifice, when internal pressure of uterine cavity power increases to a certain degree, will rupture of membranes and miscarry, and therefore usually there is no subjective symptoms before miscarriage.At present, Western medicine cannot effectively be treated habitual abortion, and Long-term taking medicine has more side effect, and therefore, people exist very large demand to the Chinese medicine of effective treatment habitual abortion.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment habitual abortion, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat habitual abortion.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention is to select Herba Schizonepetae, Semen sojae atricolor, Radix Adenophorae, Fructus Amomi, Herba Epimedii, Fructus Ligustri Lucidi, Fructus Mume, Folium Artemisiae Argyi, Fructus Alpiniae Oxyphyllae, Radix Morindae Officinalis, Herba Eupatorii, Rhizoma Chuanxiong, Herba Taxilli, Rhizoma Zingiberis Recens, Cornu Cervi Degelatinatum, Herba Dendrobii, Os Draconis, Seem Lablab Album, Rhizoma Corydalis, Rhizoma Cimicifugae, Rhizoma Cibotii, Endothelium Corneum Gigeriae Galli, Fluoritum, Herba Agrimoniae, Fructus Lycii, Fructus Schisandrae Chinensis, Caulis Perillae, Rhizoma Coptidis, Radix Ginseng, Carnis Testudinis, Carnis sepiellae seu sepiae, Ramulus Mume, the Radix Paeoniae Alba, Placenta Hominis, Fructus Jujubae medicine combines, make each efficacy of drugs produce synergism these drug regimens, thereby recurrence that can fast treating habitual abortion.Wherein select Herba Schizonepetae to be because its nature and flavor are pungent, temperature, enters lung, Liver Channel, delivers, dispel the wind, and the function for the treatment of blood disorders, parch to black hemostasis, the heating that cures cold, headache, laryngopharynx swelling and pain, apoplexy locked mouth, spits blood, and epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Select Semen sojae atricolor to be because its nature and flavor are sweet, flat, enter spleen, kidney channel, invigorate blood circulation, diuretic, dispels the wind, the function of removing toxic substances, the swelling of harnessing the river is full, pathogenic wind-toxic beriberi, jaundice clonic spasm of the muscle, puerperal puerperal tetanus, locked mouth, carbuncle sore tumefacting virus; Separate poison of drug.Select Radix Adenophorae to be because its nature and flavor are sweet, be slightly cold, attach to the lung and stomach meridians, have nourishing YIN and clearing away lung-heat, reduce phlegm, the function of QI invigorating, controls lung-heat type cough, deficiency of YIN phthisical cough, and dry cough expectorant is glutinous, deficiency of both vital energy and Yin, restlessness and fever with thirst.Select Fructus Amomi to be because its nature and flavor are pungent, temperature, enters spleen, stomach warp, has in circulation of qi promoting tune, and stomach function regulating, the function of being amusing, control stomachache painful abdominal mass swollen, and anorexia dyspepsia, chokes every vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.Selecting Herba Epimedii is that temperature, enters liver, kidney channel, has kidney invigorating and YANG supporting because of its property acrid-sweet flavor, and the function of expelling wind and removing dampness is controlled sexual impotence erectile problem, dribbling urination, and muscles and bones contraction is anxious, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, four feet are meciless.Select Fructus Ligustri Lucidi to be because its property bitter but sweet flavor is flat, enter liver, kidney channel, have invigorating the liver and kidney, the function of strong waist knee joint, controls yin asthenia generating intrinsic heat, dizziness, order flower tinnitus, soreness of the waist and knees, early whitening of beard and hair.Select Fructus Mume to be because its nature and flavor are sour, temperature, enters liver, spleen, and lung, large intestine channel, has convergence to promote the production of body fluid, and the function of relieving colic caused by ascaris anthelmintic, controls chronic cough, deficiency-heat excessive thirst, chronic malaria, dysentery, has blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis, psoriasis, bulbar conjunctiva polyp.Selecting Folium Artemisiae Argyi is because of its nature and flavor toil, temperature.Enter spleen, liver, kidney channel.The blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive.Control trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery, tells nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.Select Fructus Alpiniae Oxyphyllae to be because its nature and flavor are pungent, temperature, enters spleen, kidney channel, has warming the spleen, warming the kidney, solid and gas, the function of arresting seminal emission, controls cold air stomachache, invasion by pathogenic cold is vomited and diarrhoea, many salivas, seminal emission, dribbling urination, night many urine.Selecting Radix Morindae Officinalis is that temperature, enters liver, kidney channel, has kidney-replenishing because of its property acrid-sweet flavor, strengthening bone and muscle, and the function of wind-damp dispelling, controls sexual impotence, few abdomen cold type of pain, incontinence of urine, deficiency-cold of uterus, anemofrigid-damp arthralgia, soreness of waist and knee joint.Select Herba Eupatorii to be because its nature and flavor are pungent, flat, enter spleen, stomach warp, have clearing away summer-heat, ward off dirty, removing dampness, the function of regulating menstruation, controls and experiences heat-damp in summer, cold and heat headache, accumulates in damp, gastral cavity painful abdominal mass is not hungry, sweet taste in the mouth greasy fur, menoxenia.Select Rhizoma Chuanxiong to be because its nature and flavor are pungent, temperature, enters liver, gallbladder meridian, has activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache revolve dizzy, hypochondriac pain abdomen pain, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Select Herba Taxilli to be because its property bitter but sweet flavor is flat, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive function, controls soreness of waist and knee joint, a little less than muscles and bones flaccidity, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enters lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting, opens the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Cornu Cervi Degelatinatum to be because its nature and flavor are salty, temperature, enters liver, kidney channel, has tonify deficiency, and supporing yang function, controls insufficiency of kidney-YANG, ache of the spinal column, Deficiency and coldness of spleen and stomach, vomiting, anorexia and loose stool, deficiency-cold of uterus, bleeding not during menses.Select Herba Dendrobii to be because its property slightly sweet flavor is micro-salty, cold, enter to have, lung, kidney channel, there is the stomach reinforcing of promoting the production of body fluid, the function of clearing away heat and nourishing YIN, controls consumption of body fluid caused by febrile disease, and xerostomia is tired drinks, deficiency-heat after being ill, it is dark that the moon is hindered order.Select Os Draconis to be because its property sweet-puckery flavor is flat, be included into the heart, liver, kidney, large intestine channel, have tranquillizing the mind by relieving convulsion, the function of arresting sweating controlling nocturnal emission with astringent drugs, controls frightened Epilepsy demented, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating.Select Seem Lablab Album to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, have spleen invigorating and in, the function of the removing dampness of relieving summer heat, controls heat-damp in summer and vomits and diarrhoea, insufficiency of the spleen vomiting, lack of appetite chronic diarrhea, water retention is quenched one's thirst, leucorrhea with red and white discharge, infantile malnutrition.Select Rhizoma Corydalis to be because its nature and flavor are arduous, temperature, enters liver, stomach warp, invigorates blood circulation, and dissipating blood stasis, regulates the flow of vital energy, and the function of pain relieving is controlled all pains of trusted subordinate's waist knee joint, menoxenia , mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.Select Rhizoma Cimicifugae to be because the sweet pungent micro-hardship of its nature and flavor is cool, enter lung, spleen, stomach warp, have yang invigorating, deliver rash, the function of removing toxic substances, controls seasonal epidemic pathogens epidemic disease labor, headache cold and heat, and laryngalgia, aphtha scar, macule is not saturating, sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women's metrorrhagia and leukorrhagia, uterus tenesmus, carbuncle sore tumefacting virus.Selecting Rhizoma Cibotii is that temperature, enters liver, kidney channel, has invigorating the liver and kidney because of its property bitter but sweet flavor, except rheumatism, and strong waist foot, the function in sharp joint, controls back ache, gonalgia flaccidity of the lower limbs, cold-damp general arthralgia, loses and drowns, and frequent micturition is passed out semen, leucorrhea.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, control stagnantly, the function of strengthening the spleen and stomach, controls food stagnation distension, vomiting regurgitation, and dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Select Fluoritum to be because its nature and flavor are sweet, temperature, enters the heart, Liver Channel, has relieving palpitation, calm the nerves, and lowering the adverse flow of QI, the function in warm uterus, controls asthenia palpitation with fear, cough with dyspnea, women's sea of blood deficiency and coldness is infertile.Select Herba Agrimoniae to be because its nature and flavor toil is flat, enter lung, liver, spleen channel, have hemostasis, the function of stomach invigorating, controls spitting of blood, spits blood, and hematuria, has blood in stool, dysentery, and bleeding not during menses, impairment caused by overstrain takes off power, carbuncle, traumatic injury, wound hemorrhage.Select Fructus Lycii to be because its nature and flavor are sweet, flat, there is nourishing kidney, lung moistening, tonifying liver, the function of improving eyesight, controls hepatic and renal YIN deficiency, and soreness of the waist and knees is had a dizzy spell, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, seminal emission.Select Fructus Schisandrae Chinensis to be because its nature and flavor are sour, temperature, enters lung, kidney channel, astringes the lung, and nourishing kidney, promotes the production of body fluid, and receives antiperspirant, and the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.Selecting Caulis Perillae is that tepor, enters spleen, stomach, lung three warps because of its property acrid-sweet flavor, regulate the flow of vital energy, and Shu Yu, pain relieving, antiabortive function, controls the stagnation of QI, dyspepsia, chest and diaphragm painful abdominal mass is vexed, epigastric pain, nausea discord.Select Rhizoma Coptidis to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, there is pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever while controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis, tells, nosebleed, hematochezia, quenches one's thirst, and infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Radix Ginseng to be because its nature and flavor are sweet micro-sweet, temperature, enters spleen, lung meridian, has strongly invigorating primordial QI, Gu de-, promote the production of body fluid, the function of calming the nerves, controls impairment caused by overstrain deficient, lack of appetite, asthenia, food is told in regurgitation, stool lingering diarrhea, empty cough with asthma is short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quenches one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Select Carnis Testudinis to be because its property sweet-salty is put down, the function that has tonifying YIN to enrich blood, controls tuberculosis hectic fever due to YIN-deficiency, chronic cough spitting of blood, chronic malaria, dysentery, hemorrhoidal hamorrhage hemorrhoidal bleeding, bones and muscles pain.Select Carnis sepiellae seu sepiae to be because its nature and flavor are salty, flat, enter liver, doublely enter kidney, there is the function of nourishing the blood and yin, control blood deficiency amenorrhea, metrorrhagia, leukorrhagia.Select Ramulus Mume to be because it is controlled married woman and is used to for a long time abortion March, three, five of Ramulus Mume, decoct thick soup and drink it, drink again Arillus Longan soup.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Selecting Placenta Hominis is because its property sweet-salty, and temperature, enters lung, liver, kidney channel, has QI invigorating, nourish blood, the function of benefit essence, control deficient, weakness and emaciation, consumptive fever hectic fever due to YIN-deficiency, cough with asthma, spitting of blood, night sweat, seminal emission, sexual impotence, women's vim and vigour are not enough, infertile or newborn few.Select Fructus Jujubae to be because its nature and flavor are sweet, temperature, enters spleen, stomach warp, has spleen reinforcing stomach function regulating, and supplementing QI for promoting the production of body fluid adjusts battalion to defend, and separates the function of poison of drug, controls insufficiency of stomach lack of appetite, the weak loose stool of spleen, and qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Herba Schizonepetae 5-15 gram of Semen sojae atricolor 10-15 gram of Radix Adenophorae 5-15 gram
Fructus Amomi 3-10 gram of Herba Epimedii 6-12 gram of Fructus Ligustri Lucidi 5-15 gram
Fructus Mume 10-20 gram of Folium Artemisiae Argyi 5-10 gram of Fructus Alpiniae Oxyphyllae 10-15 gram
Radix Morindae Officinalis 10-15 gram of Herba Eupatorii 5-10 gram of Rhizoma Chuanxiong 5-15 gram
Herba Taxilli 5-15 gram of Rhizoma Zingiberis Recens 2-9 gram of Cornu Cervi Degelatinatum 5-10 gram
10-20 gram of Seem Lablab Album 5-10 gram of Herba Dendrobii 5-15 cron bone
5-10 gram of Rhizoma Cibotii 10-20 gram of Rhizoma Corydalis 10-20 gram liter fiber crops
Endothelium Corneum Gigeriae Galli 3-10 gram of Fluoritum 15-20 gram of Herba Agrimoniae 5-15 gram
Fructus Lycii 5-15 gram of Fructus Schisandrae Chinensis 3-6 gram of Caulis Perillae 5-15 gram
Rhizoma Coptidis 2-9 gram of Radix Ginseng 2-6 gram of Carnis Testudinis 90-110 gram
Carnis sepiellae seu sepiae 90-110 gram of Ramulus Mume 25-35 gram of Radix Paeoniae Alba 5-15 gram
Placenta Hominis 90-110 gram of Fructus Jujubae 15-25 gram.
Preferable amount is
10 grams of 12 grams of Radix Adenophoraes of 10 grams of Semen sojae atricolor of Herba Schizonepetae
8 grams of 9 grams of Fructus Ligustri Lucidi of 5 grams of Herba Epimedii of Fructus Amomi
12 grams of 8 grams of Fructus Alpiniae Oxyphyllae of 15 grams of Folium Artemisiae Argyis of Fructus Mume
10 grams of 8 grams of Rhizoma Chuanxiongs of 12 grams of Herba Eupatoriis of Radix Morindae Officinalis
8 grams of 6 grams of Cornu Cervi Degelatinatums of 10 grams of Rhizoma Zingiberis Recenss of Herba Taxilli
8 grams, 15 grams of Seem Lablab Albums of Herba Dendrobii 10 cron bone
15 grams of 8 grams of Rhizoma Cibotii of Rhizoma Corydalis 15 gram liter fiber crops
10 grams of 18 grams of Herba Agrimoniaes of 5 grams of Fluoritum of Endothelium Corneum Gigeriae Galli
10 grams of 5 grams of Caulis Perillaes of 15 grams of Fructus Schisandrae Chinensis of Fructus Lycii
100 grams of 4 grams of Carnis Testudinis of 6 grams of Radix Ginsengs of Rhizoma Coptidis
10 grams of 30 grams of Radix Paeoniae Albas of 100 grams of Ramulus Mume of Carnis sepiellae seu sepiae
20 grams, 100 grams of Fructus Jujubaes of Placenta Hominis.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;
2, Semen sojae atricolor: choose clean impurity, dry;
3, Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, dry;
4, Fructus Amomi: choose decontamination and shell, smash to pieces;
5, Herba Epimedii: choose clean impurity, destemming, shredding, sieve removes chip;
6, Fructus Ligustri Lucidi: choose decontamination, clean, dry;
7, Fructus Mume: choose clean impurity, sieve dedust bits, clean, and dry;
8, Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;
9, Fructus Alpiniae Oxyphyllae: get Fructus Alpiniae Oxyphyllae and put in pot, fry to shell burned blackly, take out coldly, remove shell, get core and smash use to pieces;
10, Radix Morindae Officinalis: choose decontamination, after soaking, pump while hot core with hot water, cutting, dries;
11, Herba Eupatorii: choose clean impurity, wash, pull out, slightly, after profit, remove undesirable root, cutting, dries;
12, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
13, Herba Taxilli: wash, run through, cutting, dries;
14, Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
15, Cornu Cervi Degelatinatum: choose decontamination, hack into fritter;
16, Herba Dendrobii: get dry Herba Dendrobii, saturating with blister to eighty per cant, stewing profit, removes undesirable root and black branch, and cutting, removes thin film, dries;
17, Os Draconis: outwash earth, smash;
18, Seem Lablab Album: choose clean impurity, put in boiling water and slightly boil, heave to planting skin, pull out, immerse in cold water, slough skin, dry;
19, Rhizoma Corydalis: choose decontamination, be soaked in water, clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
20, Rhizoma Cimicifugae: choose decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
21, Rhizoma Cibotii: get sand and put in pot and make popular, add the Rhizoma Cibotii of choosing clean, fry to heaving and aobvious buff with high heat, take out, screen out sand, after wind dries in the air, hit or the yellow floss hair of scraping;
22, Endothelium Corneum Gigeriae Galli: choose decontamination, rinse and dry;
23, Fluoritum: clean earth, smash into fritter;
24, Herba Agrimoniae: remove impurity undesirable root, clean, run through, cut off, dry;
25, Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;
26, Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
27, Caulis Perillae: choose decontamination, after being soaked in water, run through, section, dries;
28, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dries in the shade;
29, Radix Ginseng: except removing LU, cutting;
30, Carnis Testudinis: after killing, reject Carapax Et Plastrum Testudinis, using fresh herb;
31, Carnis sepiellae seu sepiae: after killing, get its meat, using fresh herb;
32, Ramulus Mume: get the fresh branch stalk with leaf;
33, the Radix Paeoniae Alba: choose decontamination, size separately, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
34, Placenta Hominis: with fresh Placenta Hominis, anyhow cut open blood vessel, water is repeatedly washed and floated totally;
35, Fructus Jujubae: choose clean impurity, dry.
Two, preparation
1, by the Herba Schizonepetae of described weight, Semen sojae atricolor, Radix Adenophorae, Fructus Amomi, Herba Epimedii, Fructus Ligustri Lucidi, Fructus Mume, Folium Artemisiae Argyi, Fructus Alpiniae Oxyphyllae, Radix Morindae Officinalis, Herba Eupatorii, Rhizoma Chuanxiong, Herba Taxilli, Rhizoma Zingiberis Recens, Cornu Cervi Degelatinatum, Herba Dendrobii, Os Draconis, Seem Lablab Album, Rhizoma Corydalis, Rhizoma Cimicifugae, Rhizoma Cibotii, Endothelium Corneum Gigeriae Galli, Fluoritum, Herba Agrimoniae, Fructus Lycii, Fructus Schisandrae Chinensis, Caulis Perillae, Rhizoma Coptidis, Radix Ginseng, Carnis Testudinis, Carnis sepiellae seu sepiae, Ramulus Mume, the Radix Paeoniae Alba, Placenta Hominis, twice of Fructus Jujubae drug decocting, add for the first time 8 times of amounts of water, soak after 100 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 30 minutes, filtering decoction liquor for the first time pours in container.
2, the medicinal residues of filtration are added to 6 times of amounts of water, first boil with high heat, then use slow fire boiling 30 minutes, filter decoction liquor for the second time and pour in container.
3,, by twice decoction liquor mixing and stirring, be divided into 6 doses and take.
Medicine of the present invention has temperature compensation Liver and kidney, hemostasis, and spleen invigorating, YIN nourishing, antiabortive effect, treatment habitual abortion instant effect, short treating period, do not recur.
The specific embodiment
By test example, further set forth below the beneficial effect of medicine of the present invention, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.3kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The observations of [test example 2] Drug therapy habitual abortion of the present invention
1, physical data
Accept habitual abortion patients totally 35 examples for medical treatment.
2, diagnostic criteria
The clinical manifestation of habitual abortion is identical with general miscarriage, is also experience threatened abortion, inevitable abortion, incomplete or several stages of artificial abortion.
Early symptom:
(1) a little is hemorrhage for vagina: it is the same with the situation of general miscarriage that women suffers from early stage symptom after habitual abortion, and its vaginal hemorrhage situation may continue several days, also likely can be for weeks on end, but blood volume is generally fewer.
(2) hypogastralgia: be to be generally attended by the sensation that has a dull ache that lower abdomen has appearred in the interior a small amount of bleeding of vagina.
(3) pregnant thing is got rid of: when women discharges the pregnant thing of an intrauterine part, claim that so this some situation that remains in inside, uterus is incomplete miscarriage; If it is external that the pregnant thing of inside, uterus is got rid of women completely, be so just referred to as artificial abortion phenomenon, when this situation appears in women, should go to hospital to do the corresponding clearing heat in the pericardium timely and process, the infection problems of avoiding pregnant thing to cause in vivo women occurs.
Late period symptom:
The amount of bleeding of vagina increases, and the pain of abdominal part increases the weight of: at this moment check cervix uteri, can find expansion, or seen that foetal sac stops up at cervix uteri interruption-forming, habitual abortion has just inevitably occurred so.
3, Therapeutic Method
Select above-mentioned medicament, to early stage patient, take, each serving with 1 dose, every day, early, middle and late respectively clothes 1 time, 10 days was a course for the treatment of, took continuously 3 courses for the treatment of.
4, efficacy assessment standard
Effective: habitual abortion recovery from illness, observe half a year without bounce-back person;
Take a turn for the better: habitual abortion obviously improves, and body constitution is progressively recovered;
Invalid: habitual abortion, without change, does not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by early stage habitual abortion patients 35 examples of Drug therapy of the present invention, effective 34 examples of result, obvious effective rate is 97.14%, invalid 1 example, and total effective rate is 97.14%.

Claims (3)

1. a medicine for the treatment of habitual abortion, is characterized in that: it is to be made by the crude drug in following weight range:
Herba Schizonepetae 5-15 gram of Semen sojae atricolor 10-15 gram of Radix Adenophorae 5-15 gram
Fructus Amomi 3-10 gram of Herba Epimedii 6-12 gram of Fructus Ligustri Lucidi 5-15 gram
Fructus Mume 10-20 gram of Folium Artemisiae Argyi 5-10 gram of Fructus Alpiniae Oxyphyllae 10-15 gram
Radix Morindae Officinalis 10-15 gram of Herba Eupatorii 5-10 gram of Rhizoma Chuanxiong 5-15 gram
Herba Taxilli 5-15 gram of Rhizoma Zingiberis Recens 2-9 gram of Cornu Cervi Degelatinatum 5-10 gram
10-20 gram of Seem Lablab Album 5-10 gram of Herba Dendrobii 5-15 cron bone
5-10 gram of Rhizoma Cibotii 10-20 gram of Rhizoma Corydalis 10-20 gram liter fiber crops
Endothelium Corneum Gigeriae Galli 3-10 gram of Fluoritum 15-20 gram of Herba Agrimoniae 5-15 gram
Fructus Lycii 5-15 gram of Fructus Schisandrae Chinensis 3-6 gram of Caulis Perillae 5-15 gram
Rhizoma Coptidis 2-9 gram of Radix Ginseng 2-6 gram of Carnis Testudinis 90-110 gram
Carnis sepiellae seu sepiae 90-110 gram of Ramulus Mume 25-35 gram of Radix Paeoniae Alba 5-15 gram
Placenta Hominis 90-110 gram of Fructus Jujubae 15-25 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
10 grams of 12 grams of Radix Adenophoraes of 10 grams of Semen sojae atricolor of Herba Schizonepetae
8 grams of 9 grams of Fructus Ligustri Lucidi of 5 grams of Herba Epimedii of Fructus Amomi
12 grams of 8 grams of Fructus Alpiniae Oxyphyllae of 15 grams of Folium Artemisiae Argyis of Fructus Mume
10 grams of 8 grams of Rhizoma Chuanxiongs of 12 grams of Herba Eupatoriis of Radix Morindae Officinalis
8 grams of 6 grams of Cornu Cervi Degelatinatums of 10 grams of Rhizoma Zingiberis Recenss of Herba Taxilli
8 grams, 15 grams of Seem Lablab Albums of Herba Dendrobii 10 cron bone
15 grams of 8 grams of Rhizoma Cibotii of Rhizoma Corydalis 15 gram liter fiber crops
10 grams of 18 grams of Herba Agrimoniaes of 5 grams of Fluoritum of Endothelium Corneum Gigeriae Galli
10 grams of 5 grams of Caulis Perillaes of 15 grams of Fructus Schisandrae Chinensis of Fructus Lycii
100 grams of 4 grams of Carnis Testudinis of 6 grams of Radix Ginsengs of Rhizoma Coptidis
10 grams of 30 grams of Radix Paeoniae Albas of 100 grams of Ramulus Mume of Carnis sepiellae seu sepiae
20 grams, 100 grams of Fructus Jujubaes of Placenta Hominis.
3. according to the preparation method of medicine described in claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;
(2) Semen sojae atricolor: choose clean impurity, dry;
(3) Radix Adenophorae: remove fibrous root, clean, scrape off rough bark, dry;
(4) Fructus Amomi: choose decontamination and shell, smash to pieces;
(5) Herba Epimedii: choose clean impurity, destemming, shredding, sieve removes chip;
(6) Fructus Ligustri Lucidi: choose decontamination, clean, dry;
(7) Fructus Mume: choose clean impurity, sieve dedust bits, clean, and dry;
(8) Folium Artemisiae Argyi: choose decontamination, destemming, sieve dedust bits;
(9) Fructus Alpiniae Oxyphyllae: get Fructus Alpiniae Oxyphyllae and put in pot, fry to shell burned blackly, take out coldly, remove shell, get core and smash use to pieces;
(10) Radix Morindae Officinalis: choose decontamination, after soaking, pump while hot core with hot water, cutting, dries;
(11) Herba Eupatorii: choose clean impurity, wash, pull out, slightly, after profit, remove undesirable root, cutting, dries;
(12) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
(13) Herba Taxilli: wash, run through, cutting, dries;
(14) Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
(15) Cornu Cervi Degelatinatum: choose decontamination, hack into fritter;
(16) Herba Dendrobii: get dry Herba Dendrobii, saturating with blister to eighty per cant, stewing profit, removes undesirable root and black branch, and cutting, removes thin film, dries;
(17) Os Draconis: outwash earth, smash;
(18) Seem Lablab Album: choose clean impurity, put in boiling water and slightly boil, heave to planting skin, pull out, immerse in cold water, slough skin, dry;
(19) Rhizoma Corydalis: choose decontamination, be soaked in water, clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;
(20) Rhizoma Cimicifugae: choose decontamination, slightly foam washing is clean, pulls out, runs through, and section, dries;
(21) Rhizoma Cibotii: get sand and put in pot and make popular, add the Rhizoma Cibotii of choosing clean, fry to heaving and aobvious buff with high heat, take out, screen out sand, after wind dries in the air, hit or the yellow floss hair of scraping;
(22) Endothelium Corneum Gigeriae Galli: choose decontamination, rinse and dry;
(23) Fluoritum: clean earth, smash into fritter;
(24) Herba Agrimoniae: remove impurity undesirable root, clean, run through, cut off, dry;
(25) Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;
(26) Fructus Schisandrae Chinensis: sieve dedust bits, remove impurity, to put in food steamer and steam thoroughly, taking-up is dried;
(27) Caulis Perillae: choose decontamination, after being soaked in water, run through, section, dries;
(28) Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dries in the shade;
(29) Radix Ginseng: except removing LU, cutting;
(30) Carnis Testudinis: after killing, reject Carapax Et Plastrum Testudinis, using fresh herb;
(31) Carnis sepiellae seu sepiae: after killing, get its meat, using fresh herb;
(32) Ramulus Mume: get the fresh branch stalk with leaf;
(33) Radix Paeoniae Alba: choose decontamination, size separately, is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(34) Placenta Hominis: with fresh Placenta Hominis, anyhow cut open blood vessel, water is repeatedly washed and floated totally;
(35) Fructus Jujubae: choose clean impurity, dry;
(2) preparation
(1) by the Herba Schizonepetae of described weight, Semen sojae atricolor, Radix Adenophorae, Fructus Amomi, Herba Epimedii, Fructus Ligustri Lucidi, Fructus Mume, Folium Artemisiae Argyi, Fructus Alpiniae Oxyphyllae, Radix Morindae Officinalis, Herba Eupatorii, Rhizoma Chuanxiong, Herba Taxilli, Rhizoma Zingiberis Recens, Cornu Cervi Degelatinatum, Herba Dendrobii, Os Draconis, Seem Lablab Album, Rhizoma Corydalis, Rhizoma Cimicifugae, Rhizoma Cibotii, Endothelium Corneum Gigeriae Galli, Fluoritum, Herba Agrimoniae, Fructus Lycii, Fructus Schisandrae Chinensis, Caulis Perillae, Rhizoma Coptidis, Radix Ginseng, Carnis Testudinis, Carnis sepiellae seu sepiae, Ramulus Mume, the Radix Paeoniae Alba, Placenta Hominis, twice of Fructus Jujubae drug decocting, add for the first time 8 times of amounts of water, soak after 100 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 30 minutes, filtering decoction liquor for the first time pours in container,
(2) medicinal residues of filtration are added to 6 times of amounts of water, first boil with high heat, then use slow fire boiling 30 minutes, filter decoction liquor for the second time and pour in container;
(3), by twice decoction liquor mixing and stirring, be divided into 6 doses and take.
CN201410285222.2A 2014-06-24 2014-06-24 Medicine for treating habitual abortion and preparation method thereof Pending CN104056224A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523889A (en) * 2015-01-15 2015-04-22 邹士东 Traditional Chinese medicinal preparation for treating habitual abortion and preparing method thereof
CN106177857A (en) * 2016-08-23 2016-12-07 徐洪安 A kind of medicine treating habitual abortion and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101279073A (en) * 2008-04-10 2008-10-08 北京中泰天和科技有限公司 Chinese medicinal composition for curing habitual abortion and method of preparing the same
CN102727812A (en) * 2012-03-24 2012-10-17 廖天源 Medicine for preventing and treating habitual abortion and premature delivery and preparation method thereof
CN103055042A (en) * 2013-01-17 2013-04-24 王彦菊 Chinese medicinal herb composition for treating habitual abortion and preparation method thereof
CN103623331A (en) * 2013-12-10 2014-03-12 张朝兰 Medicine for treating habitual abortion and preparation method of medicine
CN103784850A (en) * 2014-02-13 2014-05-14 刘世顺 Chinese herbal medicine formula for treating habitual abortion and preparation method of Chinese herbal medicine

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101279073A (en) * 2008-04-10 2008-10-08 北京中泰天和科技有限公司 Chinese medicinal composition for curing habitual abortion and method of preparing the same
CN102727812A (en) * 2012-03-24 2012-10-17 廖天源 Medicine for preventing and treating habitual abortion and premature delivery and preparation method thereof
CN103055042A (en) * 2013-01-17 2013-04-24 王彦菊 Chinese medicinal herb composition for treating habitual abortion and preparation method thereof
CN103623331A (en) * 2013-12-10 2014-03-12 张朝兰 Medicine for treating habitual abortion and preparation method of medicine
CN103784850A (en) * 2014-02-13 2014-05-14 刘世顺 Chinese herbal medicine formula for treating habitual abortion and preparation method of Chinese herbal medicine

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523889A (en) * 2015-01-15 2015-04-22 邹士东 Traditional Chinese medicinal preparation for treating habitual abortion and preparing method thereof
CN104523889B (en) * 2015-01-15 2015-08-12 胡晓丽 A kind of Chinese medicine preparation for the treatment of habitual abortion and preparation method thereof
CN106177857A (en) * 2016-08-23 2016-12-07 徐洪安 A kind of medicine treating habitual abortion and preparation method thereof

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