CN103191368A - Medicine for treating leucoderma and preparation method thereof - Google Patents
Medicine for treating leucoderma and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating leucoderma and a preparation method thereof. The medicine is prepared from ligusticum wallichii, fiveleaf akebia fruit, lithospermum, artemisia anomala, motherwort fruit, fructus psoraleae, duckweed and the like according to a certain weight ratio. The medicine disclosed by the invention has the functions of smoothing liver and regulating vital energy, activating blood and dissolving stasis, and clearing away heat and toxic materials, good in curative effect and high in recovery rate in treatment of leucoderma, and fast becomes effective.
Description
Technical field
The present invention relates to a kind of leukodermic medicine and preparation method thereof for the treatment of, belong to the field of Chinese medicines.
Technical background
Vitiligo is a kind of common multiple pigmented dermatosis, and it is feature that this disease forms white macula with local or general property depigmentation, and skin lesion is local depigmentation speckle, is the Chalk color, can change red after bouncing.Leukodermic sickness rate is very high, and 1-2 people's morbidities are arranged in per 100 people of China.Wherein half just began to occur skin lesion in the past at 20 years old, and about 1/5 people has family history.Vitiligo brings very big injury for patient's physical and mental health, and at present, Western medicine is effective curing vitiligo fast, and more side effect is arranged, and therefore, there is very big demand in people to the leukodermic Chinese medicine of quick effectively treatment.
Summary of the invention
The inventor has found the leukodermic medicine of effective treatment finally, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.
Purpose of the present invention just provides a kind ofly can effectively treat leukodermic composition of medicine.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicine of the present invention selects for use Rhizoma Chuanxiong, Fructus Akebiae, Radix Arnebiae (Radix Lithospermi), Herba Artemisiae Anomalae, Semen Astragali Complanati, Fructus Leonuri, Fructus Psoraleae, Herba Spirodelae, Radix Achyranthis Bidentatae, Radix Sanguisorbae, Fructus Rubi, Fructus Jujubae, Fructus Mori, Semen Persicae, Radix Curcumae, Radix Asparagi, the Radix Angelicae Dahuricae, Herba Ecliptae, Radix Paeoniae Rubra, Herba Leonuri medicine to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat leukodermic recurrence.Wherein selecting Rhizoma Chuanxiong for use is because its nature and flavor suffering, and temperature is gone into liver, gallbladder meridian, and activating QI to alleviate the depression is arranged, dispeiling pathogenic wind and removing dampness, and the function of promoting blood circulation and stopping pain is controlled air-cooled headache and is revolved dizzyly, and the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Select for use Fructus Akebiae to be because its nature and flavor are sweet, cold, liver-smoothing, qi-regulating is arranged, promoting blood circulation and stopping pain, the function of relieving restlessness diuresis, the treating the liver peratodynia, the gastric heat food is slow-witted, excessive thirst, dysentery, lumbago, hypochondriac pain, hernia, dysmenorrhea, uterus tenesmus.Select for use Radix Arnebiae (Radix Lithospermi) to be because its nature and flavor earnestly, cold, go into percardium, Liver Channel, removing heat from blood is arranged, invigorate blood circulation, the function of heat-clearing and toxic substances removing is controlled warm macule, jaundice due to damp-heat, purpura tells, nosebleed, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Selecting Herba Artemisiae Anomalae for use is because its nature and flavor hardship, and temperature is gone into the heart, spleen channel, has removing blood stasis to stimulate the menstrual flow, and the function of healing up sore and subduing swelling is controlled amenorrhea and mass in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, Yong Du burning swelling.Select for use Semen Astragali Complanati to be because it is sweet in flavor and warm in property, go into liver, kidney channel, tonifying liver is arranged, kidney tonifying makes eye bright, the function of controlling nocturnal emission with astringent drugs, treating the liver kidney deficiency, soreness of waist and knee joint, blurred vision, seminal emission premature ejaculation, frequent micturition, the enuresis, hematuria, leucorrhea.Selecting Fructus Leonuri for use is that heart born of the same parents, Liver Channel are gone in cold, and promoting blood flow to regulate menstruation is arranged because of the sweet suffering of its nature and flavor, and the function of wind and heat dispersing is controlled menoxenia, the metrorrhagia leukorrhagia, and postnatal blood stasis is had a pain, the liver-heat headache, conjunctival congestion and swelling pain, or give birth to the nebula film.Selecting Fructus Psoraleae for use is because of its nature and flavor suffering, temperature.Go into kidney channel.Reinforcing the kidney and supporting YANG.Control the cold diarrhea of suffering from a deficiency of the kidney, the enuresis, spermatorrhea, frequent micturition, sexual impotence, chills and pain of the waist and kness, deficiency and coldness is breathed heavily and is coughed.Select for use Herba Spirodelae to be because its nature and flavor suffering is cold, go into lung meridian, diaphoresis is arranged, dispel the wind, row water, heat clearing away, the function of detoxifcation, row calentura when controlling, macule is not saturating, the wind heat urticaria, skin pruritus, edema, the difficulty in urination, the skin ulcer tinea, erysipelas is scalded.Select for use Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, go into liver, kidney channel, give birth to and use dissipating blood stasis blood, subduing inflammation is controlled gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury is ripely used invigorating the liver and kidney, and bone and muscle strengthening is controlled waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Select for use Radix Sanguisorbae to be because its nature and flavor picric acid, cold.Go into liver, large intestine channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, collapse, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.Select for use Fructus Rubi to be because its nature and flavor are sweet, acid, flat, go into liver, kidney two warps, invigorating the liver and kidney is arranged, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, the function that makes eye bright is controlled sexual impotence, seminal emission, frequency of micturition, incontinence of urine, asthenia, order is dark.Be that temperature is gone into spleen, stomach warp, and the spleen reinforcing stomach function regulating is arranged because its nature and flavor are sweet with Fructus Jujubae, supplementing QI for promoting the production of body fluid transfers battalion to defend, and separates the function of poison of drug, controls the insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid deficiency, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select for use Fructus Mori to be because its nature and flavor are sweet, cold, go into liver, kidney channel, tonifying liver is arranged, kidney tonifying relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows the function of liquid, and the treating the liver kidney yin is lost, quenches one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.Select for use Semen Persicae to be because its property bitter but sweet flavor is flat, go into the heart, liver, large intestine channel, blood stasis removing and clots absorbing is arranged, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select for use Radix Curcumae to be because its nature and flavor are arduous, the heart, lung, Liver Channel are gone in cold, have the circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs is controlled all pains of breast abdomen side of body rib, it is demented to lose the heart, the calentura coma is spitted blood epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select for use Radix Asparagi to be because its nature and flavor sweetness and bitterness is cold, go into lung, kidney channel, YIN nourishing is arranged, moisturize, lung heat clearing, the function of pathogenic fire reducing is controlled fever due to yin deficiency, and cough is spitted blood, consumptive lung disease, lung abscess, laryngopharynx swelling and pain is quenched one's thirst, constipation.Selecting the Radix Angelicae Dahuricae for use is that temperature is gone into lung, spleen, stomach warp because of its nature and flavor suffering, dispel the wind, and dampness, detumescence, the function of pain relieving is controlled headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Selecting Herba Ecliptae for use is that liver, kidney channel are gone in cold, and removing heat from blood is arranged because of its nature and flavor picric acid, hemostasis, and the kidney invigorating, the function of tonifying YIN is controlled haematemesis, hemoptysis, epistaxis, hematuria is had blood in stool, dysentery, knife injury is hemorrhage, early whitening of beard and hair, diphtheria, stranguria with turbid discharge, dysentery, pudendum pruritus due to damp pathogen.Select for use Radix Paeoniae Rubra to be because its nature and flavor hardship is slightly cold, return Liver Channel, clearing away heat and cooling blood is arranged, the function of eliminating stasis to stop pain is controlled warm poison and is gone mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， Epilepsy abdominal mass stomachache, injury from falling down, carbuncle skin infection.Select for use Herba Leonuri to be because its nature and flavor are arduous, pericardium, Liver Channel are gone in cold, invigorate blood circulation, and blood stasis dispelling, regulating menstruation, the function of the water that disappears is controlled menoxenia, controls Lou difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria is rushed down blood, the carbuncle skin infection.
The specific embodiment
The drug dose of the present invention's combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in the following weight scope
Rhizoma Chuanxiong 5-15 gram Fructus Akebiae 10-15 gram Radix Arnebiae (Radix Lithospermi) 6-15 gram
Herba Artemisiae Anomalae 15-25 gram Semen Astragali Complanati 10-15 gram Fructus Leonuri 10-15 gram
Fructus Psoraleae 15-25 gram Herba Spirodelae 10-15 gram Radix Achyranthis Bidentatae 6-15 gram
Radix Sanguisorbae 10-15 gram Fructus Rubi 5-10 gram Fructus Jujubae 5-15 gram
Fructus Mori 15-25 gram Semen Persicae 2-8 gram Radix Curcumae 5-13 gram
Radix Asparagi 5-15 gram Radix Angelicae Dahuricae 10-15 gram Herba Ecliptae 10-15 gram
Radix Paeoniae Rubra 5-10 gram Herba Leonuri 10-20 gram
Preferable amount is
Rhizoma Chuanxiong 10 gram Fructus Akebiaes 12 gram Radix Arnebiae (Radix Lithospermi)s 9 grams
Herba Artemisiae Anomalae 20 gram Semen Astragali Complanatis 12 gram Fructus Leonuris 12 grams
Fructus Psoraleae 20 gram Herba Spirodelaes 12 gram Radix Achyranthis Bidentataes 9 grams
Radix Sanguisorbae 12 gram Fructus Rubies 7 gram Fructus Jujubaes 10 grams
Fructus Mori 20 gram Semen Persicaes 5 gram Radix Curcumaes 8 grams
The Radix Asparagi 10 gram Radixs Angelicae Dahuricae 12 gram Herba Ecliptaes 12 grams
Radix Paeoniae Rubra 7 gram Herba Leonuris 15 grams
The preparation method of medicine of the present invention is as follows
One, gets the raw materials ready
1, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
2, Fructus Akebiae: clean, soak slightly, moistening is to saturating, and section is dried, or cleans and dry, and the time spent smashs to pieces;
3, Radix Arnebiae (Radix Lithospermi): clean, run through, section is dried;
4, Herba Artemisiae Anomalae: choose clean impurity, remove root, the water edulcoration soaks slightly, and cutting is dried;
5, Semen Astragali Complanati: choose decontamination, rinse silt, pull out, dry;
6, Fructus Leonuri: extract Herb during fruit maturation, dry, lay fruit, choose the debranching leaf, well sifted impurity;
7, Fructus Psoraleae: the most impurity of winnowing with a dustpan, clean, dry;
8, Herba Spirodelae: 6-9 fishes between the month, shines the scholar;
9, Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;
10, Radix Sanguisorbae: choose decontamination, wash, soak slightly, run through, be cut into sheet, dry;
11, Fructus Rubi: sieve dedust bits, choose clean impurity, remove handle;
12, Fructus Jujubae: choose clean impurity, dry;
13, Fructus Mori: wash, choose decontamination, extract long handle, dry;
14, Semen Persicae: remove duricrust impurity, put and boil in the boiling water pot to the little wrinkle of crust, pull out, immerse in the cold water, rub with the hands and remove kind of a skin, dry, it is clean to winnow with a dustpan;
15, Radix Curcumae: be soaked in water, clean, pull out to shine and dry in the air, run through, section is dried;
16, Radix Asparagi: choose decontamination, washing is clean, and moistening is even to inside and outside humidity, cutting, drying;
17, the Radix Angelicae Dahuricae: choose clean impurity, wash, soak, pull out and run through, slightly shine when not having soapy feeling to crust, again behind the moistening, chip drying;
18, Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;
19, Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping is cleaned, runs through, and shave, drying, sieve removes chip;
20, Herba Leonuri: choose decontamination, clean, run through, cutting is dried.
Two, preparation
1, Rhizoma Chuanxiong, Fructus Akebiae, Radix Arnebiae (Radix Lithospermi), Herba Artemisiae Anomalae, Semen Astragali Complanati, Fructus Leonuri, Fructus Psoraleae, Herba Spirodelae, Radix Achyranthis Bidentatae, Radix Sanguisorbae, Fructus Rubi, Fructus Jujubae, Fructus Mori, Semen Persicae, Radix Curcumae, Radix Asparagi, the Radix Angelicae Dahuricae, Herba Ecliptae, Radix Paeoniae Rubra, the Herba Leonuri medicine of described weight being added 6 times of water gagings soaks, soak after 120 minutes, intense fire decocts boiling 10 minutes, used slow fire boiling again 20 minutes, decoction liquor is poured in the container for the first time.
2, add 3 times of amounts of water for the second time, intense fire decocts boiling 10 minutes, uses slow fire boiling again 20 minutes, namely gets decoction liquor for the second time.
3, twice decoction liquor mixed, simmered in water again 10 minutes, decoction liquor is divided into 4 doses takes.
Medicine of the present invention has the effect of liver-smoothing, qi-regulating, promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing, is used for the treatment of vitiligo, short treating period, instant effect, non-relapse after healing, has no side effect.
The specific embodiment
Below further sets forth the beneficial effect of medicine of the present invention by testing example, these are tested the routine animal toxicity test of medicine of the present invention that comprised and report and clinical observation material.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 40 of rabbit, the male and female dual-purpose, body weight 2.0-2.3kg divides two groups, and 30 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, and every day, secondary serve on 7 days, observes administration reaction every day, and the result shows that two groups of rabbit activities, diet are normal, and medicine does not have bad toxic and side effects.
[test example 2] leukodermic clinical observation material of Drug therapy of the present invention
1, physical data
Accept out-patient's totally 180 examples for medical treatment, its male patient's 120 examples, female patient 60 examples.
2, diagnostic criteria
The vitiligo clinical manifestation: speckle or the patch of the white of depigmentation appears in skin surface.Be normal skin on every side.The decolouring speckle differs in size from several millimeters to several centimetres, and in progressive stage, skin lesion can enlarge gradually, and constantly has new decolouring speckle to occur.The more shallow patient of the colour of skin, white macula can be not obvious, but dark-complexioned people, color contrast is then very distinct.Under the wood lamp, vitiligo position and surrounding skin have very obvious limit.Vitiligo can be involved any position of health, and bilateral is symmetrically distributed usually.The probability that hair bleaches is 10%-60%.
3, Therapeutic Method
Select above-mentioned medicament for use, take to the patient, take 1 dose at every turn, every day is early, middle and late respectively obeys 1 time, and 20 days is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Produce effects: vitiligo transference cure, body constitution recover normal, observe and do not have the recidivist half a year;
Take a turn for the better: the vitiligo symptom is clearly better, and body constitution is progressively recovered;
Invalid: as not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, with Drug therapy patients with vitiligo 180 examples of the present invention, produce effects 172 examples as a result, obvious effective rate is 95.56%, 6 examples that take a turn for the better, improvement rate is 3.33%, invalid 2 examples, total effective rate is 98.89%.
Claims (3)
1. treat leukodermic medicine for one kind, it is characterized in that: it is to be made by the crude drug in the following weight range:
Rhizoma Chuanxiong 5-15 gram Fructus Akebiae 10-15 gram Radix Arnebiae (Radix Lithospermi) 6-15 gram
Herba Artemisiae Anomalae 15-25 gram Semen Astragali Complanati 10-15 gram Fructus Leonuri 10-15 gram
Fructus Psoraleae 15-25 gram Herba Spirodelae 10-15 gram Radix Achyranthis Bidentatae 6-15 gram
Radix Sanguisorbae 10-15 gram Fructus Rubi 5-10 gram Fructus Jujubae 5-15 gram
Fructus Mori 15-25 gram Semen Persicae 2-8 gram Radix Curcumae 5-13 gram
Radix Asparagi 5-15 gram Radix Angelicae Dahuricae 10-15 gram Herba Ecliptae 10-15 gram
Radix Paeoniae Rubra 5-10 gram Herba Leonuri 10-20 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Rhizoma Chuanxiong 10 gram Fructus Akebiaes 12 gram Radix Arnebiae (Radix Lithospermi)s 9 grams
Herba Artemisiae Anomalae 20 gram Semen Astragali Complanatis 12 gram Fructus Leonuris 12 grams
Fructus Psoraleae 20 gram Herba Spirodelaes 12 gram Radix Achyranthis Bidentataes 9 grams
Radix Sanguisorbae 12 gram Fructus Rubies 7 gram Fructus Jujubaes 10 grams
Fructus Mori 20 gram Semen Persicaes 5 gram Radix Curcumaes 8 grams
The Radix Asparagi 10 gram Radixs Angelicae Dahuricae 12 gram Herba Ecliptaes 12 grams
Radix Paeoniae Rubra 7 gram Herba Leonuris 15 grams.
3. according to the preparation method of claim 1 or 2 described medicines, it comprises the following steps:
(1) gets the raw materials ready
(1) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
(2) Fructus Akebiae: clean, soak slightly, moistening is to saturating, and section is dried, or cleans and dry, and the time spent smashs to pieces;
(3) Radix Arnebiae (Radix Lithospermi): clean, run through, section is dried;
(4) Herba Artemisiae Anomalae: choose clean impurity, remove root, the water edulcoration soaks slightly, and cutting is dried;
(5) Semen Astragali Complanati: choose decontamination, rinse silt, pull out, dry;
(6) Fructus Leonuri: extract Herb during fruit maturation, dry, lay fruit, choose the debranching leaf, well sifted impurity;
(7) Fructus Psoraleae: the most impurity of winnowing with a dustpan, clean, dry;
(8) Herba Spirodelae: 6-9 fishes between the month, shines the scholar;
(9) Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;
(10) Radix Sanguisorbae: choose decontamination, wash, soak slightly, run through, be cut into sheet, dry;
(11) Fructus Rubi: sieve dedust bits, choose clean impurity, remove handle;
(12) Fructus Jujubae: choose clean impurity, dry;
(13) Fructus Mori: wash, choose decontamination, extract long handle, dry;
(14) Semen Persicae: remove duricrust impurity, put and boil in the boiling water pot to the little wrinkle of crust, pull out, immerse in the cold water, rub with the hands and remove kind of a skin, dry, it is clean to winnow with a dustpan;
(15) Radix Curcumae: be soaked in water, clean, pull out to shine and dry in the air, run through, section is dried;
(16) Radix Asparagi: choose decontamination, washing is clean, and moistening is even to inside and outside humidity, cutting, drying;
(17) Radix Angelicae Dahuricae: choose clean impurity, wash, soak, pull out and run through, slightly shine when not having soapy feeling to crust, again behind the moistening, chip drying;
(18) Herba Ecliptae: choose clean impurity, remove undesirable root, clean vexed, cutting is dried;
(19) Radix Paeoniae Rubra: get crude drug, remove impurity, big or small stepping is cleaned, runs through, and shave, drying, sieve removes chip;
(20) Herba Leonuri: choose decontamination, clean, run through, cutting is dried;
(2) preparation
(1) Rhizoma Chuanxiong, Fructus Akebiae, Radix Arnebiae (Radix Lithospermi), Herba Artemisiae Anomalae, Semen Astragali Complanati, Fructus Leonuri, Fructus Psoraleae, Herba Spirodelae, Radix Achyranthis Bidentatae, Radix Sanguisorbae, Fructus Rubi, Fructus Jujubae, Fructus Mori, Semen Persicae, Radix Curcumae, Radix Asparagi, the Radix Angelicae Dahuricae, Herba Ecliptae, Radix Paeoniae Rubra, the Herba Leonuri medicine of described weight being added 6 times of water gagings soaks, soak after 120 minutes, intense fire decocts boiling 10 minutes, used slow fire boiling again 20 minutes, decoction liquor is poured in the container for the first time;
(2) add 3 times of amounts of water for the second time, intense fire decocts boiling 10 minutes, uses slow fire boiling again 20 minutes, namely gets decoction liquor for the second time;
(3) twice decoction liquor mixed, simmered in water again 10 minutes, decoction liquor is divided into 4 doses takes.
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Cited By (6)
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| CN103860930A (en) * | 2014-03-19 | 2014-06-18 | 李常明 | Traditional Chinese medicine composition for effectively treating leucoderma |
| CN103948803A (en) * | 2014-05-13 | 2014-07-30 | 高伦 | Traditional Chinese medicine composition for treating leucoderma |
| CN105833150A (en) * | 2016-05-17 | 2016-08-10 | 商皓 | Externally-applied medicine for treating leucoderma |
| CN106798768A (en) * | 2017-03-06 | 2017-06-06 | 李耀宗 | It is a kind of to treat medicine of leucoderma and preparation method thereof |
| WO2018084671A1 (en) * | 2016-11-04 | 2018-05-11 | 동신대학교산학협력단 | Composition for preventing or treating pigmentation disorders |
| KR20180050162A (en) * | 2016-11-04 | 2018-05-14 | 동신대학교산학협력단 | Composition for preventing or treating pigmentary disorders caused by hypopigmentation |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860930A (en) * | 2014-03-19 | 2014-06-18 | 李常明 | Traditional Chinese medicine composition for effectively treating leucoderma |
| CN103860930B (en) * | 2014-03-19 | 2016-06-01 | 刘凤伟 | The Chinese medicine composition of a kind of effective treatment vitiligo |
| CN103948803A (en) * | 2014-05-13 | 2014-07-30 | 高伦 | Traditional Chinese medicine composition for treating leucoderma |
| CN105833150A (en) * | 2016-05-17 | 2016-08-10 | 商皓 | Externally-applied medicine for treating leucoderma |
| WO2018084671A1 (en) * | 2016-11-04 | 2018-05-11 | 동신대학교산학협력단 | Composition for preventing or treating pigmentation disorders |
| KR20180050162A (en) * | 2016-11-04 | 2018-05-14 | 동신대학교산학협력단 | Composition for preventing or treating pigmentary disorders caused by hypopigmentation |
| KR101865189B1 (en) * | 2016-11-04 | 2018-06-07 | 동신대학교산학협력단 | Composition for preventing or treating pigmentary disorders caused by hypopigmentation |
| CN106798768A (en) * | 2017-03-06 | 2017-06-06 | 李耀宗 | It is a kind of to treat medicine of leucoderma and preparation method thereof |
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