CN103638482B - A kind of medicine for the treatment of chronic urticaria and preparation method thereof - Google Patents

A kind of medicine for the treatment of chronic urticaria and preparation method thereof Download PDF

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CN103638482B
CN103638482B CN201310582089.2A CN201310582089A CN103638482B CN 103638482 B CN103638482 B CN 103638482B CN 201310582089 A CN201310582089 A CN 201310582089A CN 103638482 B CN103638482 B CN 103638482B
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蒋学
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Jilin Longtai Pharmaceutical Co.,Ltd.
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蒋学
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Abstract

The invention discloses a kind of medicine for the treatment of chronic urticaria and preparation method thereof, it is mainly prepared from according to a certain weight ratio by medicines such as Fructus Tribuli, Cortex Acanthopancis, Bombyx Batryticatus, Semen Cuscutae, Pericarpium Arecae, Herba Spirodelae, Poria, Os Draconis, Cortex Hibiscis, medicine of the present invention has heat-clearing and toxic substances removing, evacuation of pus removing blood stasis with potent drugs, the function of dispelling, collateral-activating, be used for the treatment of chronic urticaria instant effect, short treating period, non-relapse after healing.

Description

A kind of medicine for the treatment of chronic urticaria and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of chronic urticaria and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Chronic urticaria refers to and causes skin, mucosa, blood vessel that temporary inflammatory hyperemia and edema in tissue occur by various factors, and the course of disease is called chronic urticaria more than 6 weeks persons.The cause of disease is often uncertain.Clinical manifestation is that patient is sporadically at trunk, face or extremity generation welt and speckle.Show effect from every day for several times to a few days once not etc.At present, western medicine chronic urticaria poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of effectively treating chronic urticaria in people.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment chronic urticaria, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine effectively can treating chronic urticaria.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Fructus Tribuli, Cortex Acanthopancis, Bombyx Batryticatus, Semen Cuscutae, Pericarpium Arecae, Herba Spirodelae, Poria, Os Draconis, Cortex Hibisci, Caulis Polygoni Multiflori, Radix Arnebiae (Radix Lithospermi), Herba Artemisiae Scopariae, the Fructus Kochiae, Stigma Croci, Periostracum Cicadae, Zaocys, Herba Menthae, Rhizoma Curcumae, Lumbricus, Rhizoma Sparganii, Herba Epimedii, Radix Tripterygii Wilfordii, Herba Patriniae, Cacumen Platycladi, Semen Sesami Nigrum, Eupolyphaga Seu Steleophaga, Fructus Xanthii, Radix Saposhnikoviae, Cortex Zingiberis, Rhizoma Acori Graminei, Lignum cinnamomi camphorae medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of chronic urticaria.Wherein select Fructus Tribuli to be because its nature and flavor toil, temperature, enter liver, lung meridian, have loose wind, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, the function of promoting the circulation of blood, controls headache, itching over the body, and conjunctival congestion swells nebula, and fullness in the chest, cough with dyspnea , mass in the abdomen, breast is difficult, carbuncle, scrofula.Select Cortex Acanthopancis to be because its nature and flavor are pungent, temperature, enter liver, kidney channel, have wind-damp dispelling, strengthening bone and muscle, the function of blood circulation and promoting silt, controls anemofrigid-damp arthralgia, and muscles and bones contraction is anxious, lumbago, sexual impotence, flaccidity of the lower limbs, children's's walking retardation in children, edema, beriberi, skin ulcer cellulitis toxic swelling, traumatic injury impairment caused by overstrain.Bombyx Batryticatus is selected to be because its nature and flavor are pungent, salty, flat, return liver, lung meridian.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.For apoplexy facial hemiparalysis, infantile convulsion is twitched, and head is grant, sore throat, scrofula tuberculosis, rubella erysipelas.Select Semen Cuscutae to be because its property acrid-sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, beneficial marrow, the function of improving eyesight, controls soreness of waist and knee joint, and seminal emission, quench one's thirst, dripping urination, order is dark.Pericarpium Arecae is selected to be that tepor, enters spleen, stomach, intestine and small intestine warp, have therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, the function of row water, controls gastral cavity abdomen painful abdominal mass swollen, beriberi, edema because its nature and flavor are pungent.Select Herba Spirodelae to be because its nature and flavor are pungent, cold, enter lung meridian, have diaphoresis, dispel the wind, row water, heat clearing away, the function of removing toxic substances, row calentura when controlling, macule is not saturating, wind heat urticaria, skin pruritus, edema, the difficulty in urination, skin ulcer tinea, and erysipelas is scalded.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, urinary bladder channel, have row water, the function of dampness removing heat, controls dysuria, stranguria with turbid discharge, dysentery.Select Os Draconis to be because its property sweet-puckery flavor, flat, be included into the heart, liver, kidney, large intestine channel, have tranquillizing the mind by relieving convulsion, the function of arresting sweating controlling nocturnal emission with astringent drugs, control frightened Epilepsy demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating.Select Cortex Hibisci to be because its nature and flavor sweetness and bitterness, cool, enter large intestine, liver, spleen channel, have heat clearing away, dampness removing, removing toxic substances, antipruritic function, controls hemorrhoidal hamorrhage and rushes down blood, dysentery, proctoptosis, leucorrhea, scabies, hemorrhoid.Select Caulis Polygoni Multiflori to be because its property sweet and slightly bitter taste, flat, enter the heart, Liver Channel, nourish heart, calm the nerves, dredging collateral, the function of dispeling the wind, controls insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.Radix Arnebiae (Radix Lithospermi) is selected to be because its nature and flavor earnestly, are trembled with fear, entered percardium, Liver Channel, have removing heat from blood, invigorate blood circulation, the function of heat-clearing and toxic substances removing, control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.Herba Artemisiae Scopariae is selected to be because its nature and flavor toil, cool, enter liver, spleen, urinary bladder channel, have the function of clearing away heat-damp and promoting diuresis, control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Select the Fructus Kochiae to be because its nature and flavor sweetness and bitterness, cold, enter kidney, urinary bladder channel, have diuresis, the function of clearing away damp-heat, controls dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.Select Stigma Croci to be that flat, enter the heart, Liver Channel, have blood circulation promoting and blood stasis dispelling, the function of dispersing stagnation and relieving accumulation of pathogens, control troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed because its nature and flavor are sweet, spit blood, typhoid fever is gone mad, and frightened fear in a trance, women's amenorrhea, postnatal blood stasis is suffered from abdominal pain, tumbling and swelling.Select Periostracum Cicadae to be because its property sweet-salty, cool, enter lung, Liver Channel, have loose wind heat, lung qi dispersing, determine the function of convulsion, control affection due to external wind and heat, cough hoarseness, measles is sent out not smooth thoroughly, and rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Zaocys is selected to be because its nature and flavor are sweet, flat, return Liver Channel, have dispelling, collateral-activating, spasmolytic, dispelling the wind and dampness pathogens arthralgia pain, numb limbs and tense tendons, tic spasm, skin pruritus, leprosy.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Rhizoma Curcumae is selected to be that temperature, returns liver, spleen channel, have circulation of qi promoting removing blood stasis, the function , Zhi mass in the abdomen mass in the abdomen of removing food stagnancy pain relieving, blood stasis amenorrhea because its nature and flavor are pungent, bitter, food stagnation anus pain, treating swelling and pain by traumatic injury, early cervical carcinoma.Lumbricus is selected to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, have heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control high fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Select Rhizoma Sparganii to be because its nature and flavor toil, flat, enter liver, spleen channel, have removing blood stasis, circulation of qi promoting, removing food stagnancy, the function , Zhi lumps in the chest and abdomen of pain relieving, the solidifying band of QI and blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, and traumatic injury, skin ulcer swells hard.Select Herba Epimedii to be because its property acrid-sweet flavor, temperature, enters liver, kidney channel, has kidney invigorating and YANG supporting, the function of expelling wind and removing dampness, control sexual impotence erectile problem, dribbling urination, and muscles and bones contraction is anxious, and hemiplegia, weakness of the waist and knees, rheumatic arthralgia, four feet are meciless.Radix Tripterygii Wilfordii is selected to be that poison, has parasite killing, antiinflammatory, the function of removing toxic substances greatly because its nature and flavor are bitter.Herba Patriniae is selected to be that flat, enter liver, stomach, large intestine channel, have heat-clearing and toxic substances removing, the function of evacuation of pus removing blood stasis with potent drugs, controls acute appendicitis, dysentery, leucorrhea with red and white discharge, the stagnant stomachache of the stasis of blood in puerperal, conjunctival congestion and swelling pain, carbuncle scabies because its nature and flavor are bitter.Select Cacumen Platycladi to be because its nature and flavor are pained, cold, enter the heart, liver, large intestine channel, have removing heat from blood, hemostasis, wind-damp dispelling, the function of loose toxic swelling, controls haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, cough, erysipelas, and mumps is scalded.Select Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, have invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Eupolyphaga Seu Steleophaga is selected to be salty because of its nature and flavor, cold, slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea , mass in the abdomen mass in the abdomen.Fructus Xanthii is selected to be that temperature, poisonous, enter lung, Liver Channel, have loose wind, pain relieving, damp eliminating, the function of parasite killing, controls headche due to wind-cold, nasal sinusitis, toothache, anemofrigid-damp arthralgia, four foot spasm and pain, mange, pruritus because its nature and flavor are sweet.Select Radix Saposhnikoviae to be because its property acrid-sweet flavor, temperature, enters bladder, lung, spleen channel, delivers, dispel the wind, and victory is wet, and the function of pain relieving, controls affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, anemofrigid-damp arthralgia, and joint is ached, and extremity contraction is anxious, tetanus.Select Cortex Zingiberis to be because its nature and flavor are pungent, cool, enter spleen, lung two warp, have row water, the function of detumescence, swelling of harnessing the river is full.Rhizoma Acori Graminei is selected to be that tepor, enters the heart, liver, spleen channel, have and have one's ideas straightened out, eliminating phlegm, regulate the flow of vital energy, invigorate blood circulation because its nature and flavor are worked hard, loose wind, the function of drying, Zhi epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Lignum cinnamomi camphorae is selected to be that temperature, enters liver, spleen, lung meridian, have wind-damp dispelling, qi and blood circulation promotion, the function in sharp joint, control trusted subordinate's distending pain, beriberi, gout, scabies, traumatic injury because its nature and flavor are pungent.
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Fructus Tribuli 5-15 gram of Cortex Acanthopancis 10-20 gram of Bombyx Batryticatus 10-15 gram
Semen Cuscutae 5-15 gram of Pericarpium Arecae 10-20 gram of Herba Spirodelae 10-15 gram
Poria 5-15 cron bone 10-20 gram of Cortex Hibisci 10-15 gram
Caulis Polygoni Multiflori 10-20 gram of Radix Arnebiae (Radix Lithospermi) 10-20 gram of Herba Artemisiae Scopariae 15-25 gram
Fructus Kochiae 10-20 gram of Stigma Croci 10-20 gram of Periostracum Cicadae 15-25 gram
Zaocys 10-20 gram of Herba Menthae 25-35 gram of Rhizoma Curcumae 15-25 gram
Lumbricus 10-20 gram of Rhizoma Sparganii 25-35 gram of Herba Epimedii 15-25 gram
Radix Tripterygii Wilfordii 5-15 gram of Herba Patriniae 25-35 gram of Cacumen Platycladi 15-25 gram
Semen Sesami Nigrum 5-15 gram of Eupolyphaga Seu Steleophaga 25-35 gram of Fructus Xanthii 15-25 gram
Radix Saposhnikoviae 5-15 gram of Cortex Zingiberis 25-35 gram of Rhizoma Acori Graminei 15-25 gram
Lignum cinnamomi camphorae 5-15 gram
Preferable amount is
Fructus Tribuli 10 grams of Cortex Acanthopanciss 15 grams of Bombyx Batryticatus 13 grams
13 grams, Semen Cuscutae 10 grams of Pericarpium Arecae 15 grams of Herba Spirodelaes
Poria 10 cron bone 15 grams of Cortex Hibiscis 13 grams
Caulis Polygoni Multiflori 15 grams of Radix Arnebiae (Radix Lithospermi)s 15 grams of Herba Artemisiae Scopariae 20 grams
The Fructus Kochiae 15 grams of Stigma Crocis 15 grams of Periostracum Cicadaes 20 grams
Zaocys 15 grams of Herba Menthaes 30 grams of Rhizoma Curcumae 20 grams
Lumbricus 15 grams of Rhizoma Sparganii 30 grams of Herba Epimedii 20 grams
Radix Tripterygii Wilfordii 10 grams of Herba Patriniaes 30 grams of Cacumen Platycladis 20 grams
Semen Sesami Nigrum 10 grams of Eupolyphaga Seu Steleophagas 30 grams of Fructus Xanthii 20 grams
Radix Saposhnikoviae 10 grams of Cortex Zingiberiss 30 grams of Rhizoma Acori Graminei 20 grams
Lignum cinnamomi camphorae 10 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Fructus Tribuli: silt is removed in drift, the hard thorn that Ex-all is residual;
2, Cortex Acanthopancis: pick clean impurity, wash, slightly section after profit, dry;
3, Bombyx Batryticatus: get crude drug, removes residual silk, impurity;
4, Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
5, Pericarpium Arecae: pick clean impurity, rolloff makes soft, beats, sieve removes spare;
6, Herba Spirodelae: 6-9 fishes between the month, dries;
7, Poria: get Poria block, removing impurity;
8, Os Draconis: outwash earth, smash;
9, Cortex Hibisci: clean and slightly soak, run through, cutting, dry;
10, Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
11, Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;
12, Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, remove spare after square-bottomed bamboo basket;
13, the Fructus Kochiae: get crude drug, removing impurity, sieve removes chip;
14, Stigma Croci: pick decontamination, and remove yellow feeler;
15, Periostracum Cicadae: pick decontamination, cleans and dries;
16, Zaocys: get crude drug, brush away ash bits, the used time decaptitates, squama, cutting;
17, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
18, Rhizoma Curcumae: get crude drug, removing impurity, size stepping, cleans, and slightly soaks, and takes out, runs through, shave, dry, and sieve removes chip;
19, Lumbricus: pick decontamination, rinses with water, pulls out in time, dries, cutting;
20, Rhizoma Sparganii: pick clean impurity, be soaked in water, pull out and run through, section, dries;
21, Herba Epimedii: pick clean impurity, destemming, shredding, sieve removes chip;
22, Radix Tripterygii Wilfordii: the root bark that removing is residual, soaks, cleans, run through, cut sheet, and dry, sieve removes chip;
23, Herba Patriniae: get crude drug, removing impurity, with Water spray, slightly dries in the air, and cutting is dry;
24, Cacumen Platycladi: pick clean impurity, rubs broken destemming, well sifted ash bits;
25, Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
26, Eupolyphaga Seu Steleophaga: get crude drug, cleaning, drying;
27, Fructus Xanthii: pick most impurity, deburring, sieve dedust bits, micro-stir-fry is to yellow, and taking-up cools;
28, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
29, Cortex Zingiberis: the rhizome taking Rhizoma Zingiberis Recens autumn, cleans, scrapes off outer cork, dry with bamboo knife;
30, Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
31, Lignum cinnamomi camphorae: removing impurity, the section of being sawn into, is split into fritter or pound sheet.
Two, prepare
1, the Fructus Tribuli of described weight, Cortex Acanthopancis, Bombyx Batryticatus, Semen Cuscutae, Pericarpium Arecae, Herba Spirodelae, Poria, Os Draconis, Cortex Hibisci, Caulis Polygoni Multiflori, Radix Arnebiae (Radix Lithospermi), Herba Artemisiae Scopariae, the Fructus Kochiae, Stigma Croci, Periostracum Cicadae, Zaocys, Herba Menthae, Rhizoma Curcumae, Lumbricus, Rhizoma Sparganii, Herba Epimedii, Radix Tripterygii Wilfordii, Herba Patriniae, Cacumen Platycladi, Semen Sesami Nigrum, Eupolyphaga Seu Steleophaga, Fructus Xanthii, Radix Saposhnikoviae, Cortex Zingiberis, Rhizoma Acori Graminei, Lignum cinnamomi camphorae medicine are decocted with water secondary, add water 6 times amount for the first time, soak after 100 minutes, intense fire decocts boiling 20 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor.
2, add water the medicinal residues of filtration 4 times amount, first boils with high heat, then use slow fire boiling 30 minutes, filters to obtain second time decoction liquor.
3, twice decoction liquor is carried out mixing and stirring, be divided into 3 doses and take.
Medicine of the present invention has heat-clearing and toxic substances removing, evacuation of pus removing blood stasis with potent drugs, and the function of dispelling, collateral-activating, is used for the treatment of chronic urticaria, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] Drug therapy chronic urticaria of the present invention:
1, physical data
Accept out-patient's totally 160 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation: before rubella wheal occurs, local skin is itched or had tingling, occurs erythra rapidly.There is General Symptoms in some patients, as bad in appetite, general malaise, headache or heating in rubella wheal number hour or 1 ~ 2 day.Rubella wheal shows as flat rubescent or glaucous edemous speckle, and there is blush at edge.Rubella wheal can claim ring-type urticaria ringwise, and several adjacent ring-like lesion can connect or merge and form map shape, can be described as figure urticaria.Have in rubella wheal during vesicle and be called vesicle urticaria.
Size and the number of rubella wheal are indefinite, can appear at the skin at any position, mucosa.Rubella wheal causes play to itch, acupuncture or burning sensation, and each one degree is different.Have the General Symptoms such as headache, heating time serious, especially acute urticaria patient is heatable reaches about 40 DEG C, and blood pressure can reduce even generation and faint and shock.The rubella wheal that most patient is only itched and without other symptoms.The course of disease of rubella wheal is indefinite, and what have erythra for several times occurred within one day, stops outbreak, be called acute urticaria after a few days or 1 ~ 2 thoughtful several weeks.There is erythra in many patients, or occur time and again by spells or increase the weight of, alleviate or disappear everyday, for several months or several years, can be called chronic urticaria.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: transference cure, body constitution recovers normal, observes half a year without recidivist;
Take a turn for the better: symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy chronic urticaria patients 160 example of the present invention, effective 154 examples of result, obvious effective rate is 96.25%, and take a turn for the better 4 examples, and improvement rate is 2.5%, and invalid 2 examples, total effective rate is 98.75%.

Claims (3)

1. treat a medicine for chronic urticaria, it is characterized in that: it is made up of the crude drug in following weight range:
Fructus Tribuli 5-15 gram of Cortex Acanthopancis 10-20 gram of Bombyx Batryticatus 10-15 gram
Semen Cuscutae 5-15 gram of Pericarpium Arecae 10-20 gram of Herba Spirodelae 10-15 gram
Poria 5-15 cron bone 10-20 gram of Cortex Hibisci 10-15 gram
Caulis Polygoni Multiflori 10-20 gram of Radix Arnebiae (Radix Lithospermi) 10-20 gram of Herba Artemisiae Scopariae 15-25 gram
Fructus Kochiae 10-20 gram of Stigma Croci 10-20 gram of Periostracum Cicadae 15-25 gram
Zaocys 10-20 gram of Herba Menthae 25-35 gram of Rhizoma Curcumae 15-25 gram
Lumbricus 10-20 gram of Rhizoma Sparganii 25-35 gram of Herba Epimedii 15-25 gram
Radix Tripterygii Wilfordii 5-15 gram of Herba Patriniae 25-35 gram of Cacumen Platycladi 15-25 gram
Semen Sesami Nigrum 5-15 gram of Eupolyphaga Seu Steleophaga 25-35 gram of Fructus Xanthii 15-25 gram
Radix Saposhnikoviae 5-15 gram of Cortex Zingiberis 25-35 gram of Rhizoma Acori Graminei 15-25 gram
Lignum cinnamomi camphorae 5-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Fructus Tribuli 10 grams of Cortex Acanthopanciss 15 grams of Bombyx Batryticatus 13 grams
13 grams, Semen Cuscutae 10 grams of Pericarpium Arecae 15 grams of Herba Spirodelaes
Poria 10 cron bone 15 grams of Cortex Hibiscis 13 grams
Caulis Polygoni Multiflori 15 grams of Radix Arnebiae (Radix Lithospermi)s 15 grams of Herba Artemisiae Scopariae 20 grams
The Fructus Kochiae 15 grams of Stigma Crocis 15 grams of Periostracum Cicadaes 20 grams
Zaocys 15 grams of Herba Menthaes 30 grams of Rhizoma Curcumae 20 grams
Lumbricus 15 grams of Rhizoma Sparganii 30 grams of Herba Epimedii 20 grams
Radix Tripterygii Wilfordii 10 grams of Herba Patriniaes 30 grams of Cacumen Platycladis 20 grams
Semen Sesami Nigrum 10 grams of Eupolyphaga Seu Steleophagas 30 grams of Fructus Xanthii 20 grams
Radix Saposhnikoviae 10 grams of Cortex Zingiberiss 30 grams of Rhizoma Acori Graminei 20 grams
Lignum cinnamomi camphorae 10 grams.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Fructus Tribuli: silt is removed in drift, the hard thorn that Ex-all is residual;
(2) Cortex Acanthopancis: pick clean impurity, wash, slightly section after profit, dry;
(3) Bombyx Batryticatus: get crude drug, removes residual silk, impurity;
(4) Semen Cuscutae: cross square-bottomed bamboo basket and remove impurity, clean, dry;
(5) Pericarpium Arecae: pick clean impurity, rolloff makes soft, beats, sieve removes spare;
(6) Herba Spirodelae: 6-9 fishes between the month, dries;
(7) Poria: get Poria block, removing impurity;
(8) Os Draconis: outwash earth, smash;
(9) Cortex Hibisci: clean and slightly soak, run through, cutting, dry;
(10) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(11) Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;
(12) Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, remove spare after square-bottomed bamboo basket;
(13) Fructus Kochiae: get crude drug, removing impurity, sieve removes chip;
(14) Stigma Croci: pick decontamination, and remove yellow feeler;
(15) Periostracum Cicadae: pick decontamination, cleans and dries;
(16) Zaocys: get crude drug, brush away ash bits, the used time decaptitates, squama, cutting;
(17) Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
(18) Rhizoma Curcumae: get crude drug, removing impurity, size stepping, cleans, and slightly soaks, and takes out, runs through, shave, dry, and sieve removes chip;
(19) Lumbricus: pick decontamination, rinses with water, pulls out in time, dries, cutting;
(20) Rhizoma Sparganii: pick clean impurity, be soaked in water, pull out and run through, section, dries;
(21) Herba Epimedii: pick clean impurity, destemming, shredding, sieve removes chip;
(22) Radix Tripterygii Wilfordii: the root bark that removing is residual, soaks, cleans, run through, cut sheet, and dry, sieve removes chip;
(23) Herba Patriniae: get crude drug, removing impurity, with Water spray, slightly dries in the air, and cutting is dry;
(24) Cacumen Platycladi: pick clean impurity, rubs broken destemming, well sifted ash bits;
(25) Semen Sesami Nigrum: get crude drug, removing impurity, sieve removes chip;
(26) Eupolyphaga Seu Steleophaga: get crude drug, cleaning, drying;
(27) Fructus Xanthii: pick most impurity, deburring, sieve dedust bits, micro-stir-fry is to yellow, and taking-up cools;
(28) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(29) Cortex Zingiberis: the rhizome taking Rhizoma Zingiberis Recens autumn, cleans, scrapes off outer cork, dry with bamboo knife;
(30) Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
(31) Lignum cinnamomi camphorae: removing impurity, the section of being sawn into, is split into fritter or pound sheet;
(2) prepare
(1) Fructus Tribuli of described weight, Cortex Acanthopancis, Bombyx Batryticatus, Semen Cuscutae, Pericarpium Arecae, Herba Spirodelae, Poria, Os Draconis, Cortex Hibisci, Caulis Polygoni Multiflori, Radix Arnebiae (Radix Lithospermi), Herba Artemisiae Scopariae, the Fructus Kochiae, Stigma Croci, Periostracum Cicadae, Zaocys, Herba Menthae, Rhizoma Curcumae, Lumbricus, Rhizoma Sparganii, Herba Epimedii, Radix Tripterygii Wilfordii, Herba Patriniae, Cacumen Platycladi, Semen Sesami Nigrum, Eupolyphaga Seu Steleophaga, Fructus Xanthii, Radix Saposhnikoviae, Cortex Zingiberis, Rhizoma Acori Graminei, Lignum cinnamomi camphorae are decocted with water secondary, add water 6 times amount for the first time, soak after 100 minutes, intense fire decocts boiling 20 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor;
(2) add water the medicinal residues of filtration 4 times amount, first boils with high heat, then use slow fire boiling 30 minutes, filters to obtain second time decoction liquor;
(3) twice decoction liquor is carried out mixing and stirring, be divided into 3 doses and take.
CN201310582089.2A 2013-11-20 2013-11-20 A kind of medicine for the treatment of chronic urticaria and preparation method thereof Active CN103638482B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1923244A (en) * 2006-03-06 2007-03-07 王积善 Medicinal composition for treating dermatosis, preparation process and use thereof
CN101961415A (en) * 2010-09-20 2011-02-02 侯洪领 Decoction for treating chronic urticaria

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1923244A (en) * 2006-03-06 2007-03-07 王积善 Medicinal composition for treating dermatosis, preparation process and use thereof
CN101961415A (en) * 2010-09-20 2011-02-02 侯洪领 Decoction for treating chronic urticaria

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中医分型治疗荨麻疹150例;姚晓虹;《陕西中医函授》;19910630(第03期);22-24 *
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