CN105477545A - Medicine for treating cerebral thrombosis and preparation method of medicine - Google Patents

Medicine for treating cerebral thrombosis and preparation method of medicine Download PDF

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CN105477545A
CN105477545A CN201510945670.5A CN201510945670A CN105477545A CN 105477545 A CN105477545 A CN 105477545A CN 201510945670 A CN201510945670 A CN 201510945670A CN 105477545 A CN105477545 A CN 105477545A
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radix
grams
gram
rhizoma
dry
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张朝兰
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张朝兰
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Abstract

The invention discloses a medicine for treating cerebral thrombosis and a preparation method of the medicine. The medicine is mainly prepared from radix astragali, suberect spatholobus stem, radix salviae miltiorrhizae, radix paeoniae rubra, glossy privet fruit, radix ophiopogonis, ramulus uncariae cum uncis, earthworm, herba taxilli, trichosanthes kirilowii maxim, flos carthami, radix curcumae, radix angelicae sinensis, ligusticum wallichii, liquorice root, fruit of Chinese wolfberry, spina gleditsiae, myrrh, radix dipsaci, radix sileris, rhizoma acori graminei, rhizoma arisaematis, spica prunellae, semen cassia, caulis bambusae in taeniam, rhizoma gastrodiae, radix codonopsis, polygala tenuifolia and rhizoma anemarrhenae in certain percentage by weight. The medicine disclosed by the invention has functions of regulating qi and relieving depression, activating blood and promoting menstruation, cooling blood and removing blood stasis, removing stasis and relieving pain; and the medicine, on treating the cerebral thrombosis, is rapid to take effect, good in curative effect and free from reoccurrence.

Description

A kind of medicine for the treatment of cerebral thrombosis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of cerebral thrombosis and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Cerebral thrombosis is that cerebral arteries trunk or cortical branches atherosclerosis cause Aldosterone, luminal stenosis obturation and thrombosis, and cause brain regional blood flow to reduce or blood supply interruption, brain tissue ischemia anoxia causes the focal neurological symptom of softening downright bad appearance.The traditional Chinese medical science then thinks cerebral thrombosis and blood stasis due to qi deficiency, and excessive rising of liver-YANG, phlegm stagnation in collateral is relevant.Because western medicine side effect is large, therefore there is great demand to the Chinese medicine of effectively treating cerebral thrombosis in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment cerebral thrombosis, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment cerebral thrombosis.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects the Radix Astragali, Caulis Spatholobi, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Fructus Ligustri Lucidi, Radix Ophiopogonis, Ramulus Uncariae Cum Uncis, Pheretima, Herba Taxilli, Fructus Trichosanthis, Flos Carthami, Radix Curcumae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Fructus Lycii, Spina Gleditsiae, Myrrha, Radix Dipsaci, Radix Saposhnikoviae, Rhizoma Acori Graminei, Rhizoma Arisaematis, Spica Prunellae, Semen Cassiae, Caulis Bambusae In Taenia, Rhizoma Gastrodiae, Radix Codonopsis, Radix Polygalae, the Rhizoma Anemarrhenae, Radix Puerariae, the Rhizoma Pinelliae, Herba Epimedii medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat cerebral thrombosis.Wherein, select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Caulis Spatholobi to be because its property bitter but sweet flavor, temperature, enters the heart, spleen two warp, have invigorate blood circulation, the function of relaxing muscles and tendons, control soreness of waist and knee joint, paralysis and numbness, menoxenia.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have blood circulation and promoting silt, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina pectoris, menoxenia, dysmenorrhea, and to close, metrorrhagia leukorrhagia , mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Select Fructus Ligustri Lucidi to be because its property bitter but sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, the function of strong waist knee joint, controls yin asthenia generating intrinsic heat, dizzy, order flower tinnitus, soreness of the waist and knees, early whitening of beard and hair.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor are bitter, cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclampsia.Pheretima is selected to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, have heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control high fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Select Herba Taxilli to be because its property bitter but sweet flavor, flat, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive function, controls soreness of waist and knee joint, and muscles and bones flaccidity is weak, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Select Fructus Trichosanthis to be because sweet, the micro-hardship of its nature and flavor, cold, return lung, stomach, large intestine channel, have clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize the function of laxation, control cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, acute appendicitis, constipation.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Radix Curcumae is selected to be because its nature and flavor are worked hard, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Radix Glycyrrhizae is selected to be because its nature and flavor are sweet, flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription; Process use, control taste lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus , Jing Epilepsy; Raw use, controls laryngopharynx swelling and pain, peptic ulcer, carbuncle subcutaneous ulcer skin infection, separates poison of drug and alimentary toxicosis.Select Fructus Lycii to be that flat, have nourishing kidney, lung moistening, tonifying liver, the function of improving eyesight, controls hepatic and renal YIN deficiency, and soreness of the waist and knees is had a dizzy spell, the many tear of blurred vision, and cough due to consumptive disease, quenches one's thirst because its nature and flavor are sweet, lose clear.Select Spina Gleditsiae to be that temperature, searches wind, draw out pus by applying a plaster to the affected part because its nature and flavor are pungent, detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Myrrha is selected to be that flat, enter Liver Channel, have loose blood blood stasis removing, the function of subduing swelling and relieving pain, controls and fall damage, incised wound, muscles and bones, trusted subordinate all Tong , mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye because its nature and flavor are bitter.Select Radix Dipsaci to be that tepor, enters liver, kidney channel, have invigorating the liver and kidney, reuniting the fractured tendons and bones, and the function of blood circulation regulating, controls aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia because its nature and flavor toil, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.Select Radix Saposhnikoviae to be because its property acrid-sweet flavor, temperature, enters bladder, lung, spleen channel, delivers, dispel the wind, and victory is wet, and the function of pain relieving, controls affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, anemofrigid-damp arthralgia, and joint is ached, and extremity contraction is anxious, tetanus.Select Rhizoma Acori Graminei because its nature and flavor are pungent, tepor.Enter the heart, liver, spleen channel.Have one's ideas straightened out, eliminating phlegm, regulates the flow of vital energy, and invigorates blood circulation, and loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura god is wrong, forgetful, deafness with qi stagnation, and ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Selection of rhizoma arisaematis because its bitter taste XinWen in property, with dry wet phlegm, wind to calm the frightened, the function of detumescence fights, stroke, phlegm indicates, mouth askew, hemiparalysis, epilepsy, present concern.charlotte.Select Spica Prunellae to be because its nature and flavor toil, cold, enter liver, gallbladder meridian, have liver heat removing, the function of eliminating stagnation, controls scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Semen Cassiae is selected to be because its property bitter but sweet flavor, cool, enter liver, kidney channel, have liver heat removing, improving eyesight, diuretic, the function of relieving constipation, control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, liver cirrhosis abdomen, habitual constipation.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduce phlegm, the function of emesis, control dysphoria with smothery sensation vomiting, singultus, expectorant heat syndrome cough is breathed heavily, and spits blood, epistaxis, metrorrhagia, malignant histocytosis, fetal movement , Jing Epilepsy.Select Rhizoma Gastrodiae to be because its nature and flavor are sweet, flat, enter Liver Channel, have endogenous wind stopping, the function of arresting convulsion, control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia, aphasia, little Jing Epilepsy wind symptom.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Select Radix Polygalae to be because its nature and flavor toil, temperature, enter the heart, kidney channel, have Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, the function of resolving depression, controls palpitation with fear, forgetful, nocturnal emission, insomnia, cough ant phlegm, and carbuncle skin ulcer swells.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, have yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is quenched the thirst, cure the wound cold, warm, headache, stiffness of the nape, dysphoria with smothery sensation disappears and drinks, and has loose bowels, dysentery, and abnormal pigmentary deposit on the skin is examined not saturating, hypertension, and angina pectoris is deaf.Select the Rhizoma Pinelliae to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, stomach warp, have drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass, control damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, outer subduing inflammation.Select Herba Epimedii to be because its property acrid-sweet flavor, temperature, enters liver, kidney channel, has kidney invigorating and YANG supporting, the function of expelling wind and removing dampness, control sexual impotence erectile problem, dribbling urination, and muscles and bones contraction is anxious, and hemiplegia, weakness of the waist and knees, rheumatic arthralgia, four feet are meciless.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Radix Astragali 15-20 gram, Caulis Spatholobi 10-20 gram, Radix Salviae Miltiorrhizae 15-20 gram, Radix Paeoniae Rubra 10-20 gram, Fructus Ligustri Lucidi 10-15 gram, Radix Ophiopogonis 5-15 gram, Ramulus Uncariae Cum Uncis 10-20 gram, Pheretima 5-15 gram, Herba Taxilli 15-20 gram, Fructus Trichosanthis 10-20 gram, Flos Carthami 7-12 gram, Radix Curcumae 10-20 gram, Radix Angelicae Sinensis 5-15 gram, Rhizoma Chuanxiong 15-20 gram, Radix Glycyrrhizae 7-12 gram, Fructus Lycii 10-20 gram, Spina Gleditsiae 10-20 gram, Myrrha 5-15 gram, Radix Dipsaci 5-15 gram, Radix Saposhnikoviae 10-20 gram, Rhizoma Acori Graminei 5-15 gram, Rhizoma Arisaematis 4-10 gram, Spica Prunellae 10-20 gram, Semen Cassiae 5-15 gram, Caulis Bambusae In Taenia 10-15 gram, Rhizoma Gastrodiae 5-15 gram, Radix Codonopsis 10-15 gram, Radix Polygalae 5-15 gram, Rhizoma Anemarrhenae 7-12 gram, Radix Puerariae 5-15 gram, Rhizoma Pinelliae 5-15 gram, Herba Epimedii 5-15 gram.
Be preferably:
The Radix Astragali 18 grams, Caulis Spatholobi 15 grams, Radix Salviae Miltiorrhizae 18 grams, Radix Paeoniae Rubra 15 grams, Fructus Ligustri Lucidi 12 grams, Radix Ophiopogonis 10 grams, Ramulus Uncariae Cum Uncis 15 grams, Pheretima 10 grams, Herba Taxilli 18 grams, Fructus Trichosanthis 15 grams, 9 grams, Flos Carthami, Radix Curcumae 15 grams, Radix Angelicae Sinensis 10 grams, Rhizoma Chuanxiong 18 grams, 9 grams, Radix Glycyrrhizae, Fructus Lycii 15 grams, Spina Gleditsiae 15 grams, Myrrha 10 grams, Radix Dipsaci 10 grams, Radix Saposhnikoviae 15 grams, Rhizoma Acori Graminei 10 grams, Rhizoma Arisaematis 8 grams, Spica Prunellae 15 grams, Semen Cassiae 10 grams, Caulis Bambusae In Taenia 12 grams, 10 grams, Rhizoma Gastrodiae, Radix Codonopsis 12 grams, Radix Polygalae 10 grams, the Rhizoma Anemarrhenae 9 grams, Radix Puerariae 10 grams, the Rhizoma Pinelliae 10 grams, Herba Epimedii 15 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
2, Caulis Spatholobi: run through with water, section, or steam soft after take advantage of fervent sheet, dry;
3, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
4, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
5, Fructus Ligustri Lucidi: pick decontamination, cleans, dries;
6, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
7, Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
8, Pheretima: pick decontamination, rinses with water, pulls out in time, dries, cutting;
9, Herba Taxilli: wash, runs through, and cutting is dried;
10, Fructus Trichosanthis: get crude drug, removing impurity and fruit stem, clean, and flattens, shredding or fritter, dry;
11, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
12, Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
13, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
14, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
15, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
16, Fructus Lycii: clean impurity of winnowing with a dustpan, plucks residual stalk and the base of a fruit;
17, Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;
18, Myrrha: pick decontamination, breaks into fragment;
19, Radix Dipsaci: clean silt, removing retained root head, runs through rear section and dries, sieve anti-dandruff;
20, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
21, Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
22, Rhizoma Arisaematis: pick decontamination, cleans ash bits, dries;
23, Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
24, Semen Cassiae: get clean Semen Cassiae, putting in pot to fry has fragrance to micro-, takes out, cools;
25, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;
26, Rhizoma Gastrodiae: be laid in by Rhizoma Gastrodiae slice and sprayed on the watch core paper of water, put in pot, burns sallow to paper color with slow fire, is constantly stirred by tablet to two sides strong yellow as spending;
27, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
28, Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
29, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
30, Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;
31, the Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
32, Herba Epimedii: pick clean impurity, destemming, shredding, sieve removes chip.
Two, prepare
1, by the Radix Astragali cooked, Caulis Spatholobi, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Fructus Ligustri Lucidi, Radix Ophiopogonis, Ramulus Uncariae Cum Uncis, Pheretima, Herba Taxilli, Fructus Trichosanthis, Flos Carthami, Radix Curcumae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Fructus Lycii, Spina Gleditsiae, Myrrha, Radix Dipsaci, Radix Saposhnikoviae, Rhizoma Acori Graminei, Rhizoma Arisaematis, Spica Prunellae, Semen Cassiae, Caulis Bambusae In Taenia, Rhizoma Gastrodiae, Radix Codonopsis, Radix Polygalae, the Rhizoma Anemarrhenae, Radix Puerariae, the Rhizoma Pinelliae, Herba Epimedii puts into decocting container, add water 8 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, the medicinal residues of filtration are added 6 times amount, intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, by twice decoction liquor mixing and stirring and get final product, 4 doses are divided into take.
In prescription, Rhizoma Gastrodiae has the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. to be monarch drug; Flos Carthami promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving; Radix Angelicae Sinensis has benefiting blood and regulating blood circulation, moisturizes laxation, controls the function of headache due to deficiency of blood, the two is ministerial drug, and three taste medicines play the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., promoting blood circulation to restore menstrual flow jointly, blood stasis removing pain relieving, moisturizes the effect of laxation, and treatment cerebral thrombosis effect is comprehensive, and with promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving, the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. is that master can be effected a permanent cure, Myrrha has loose blood blood stasis removing, and the function of subduing swelling and relieving pain is adjuvant drug, Radix Curcumae have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, for making medicine, is take stopgap measures with all medicines of remainder.
Medicine of the present invention has activating QI to alleviate the depression, promoting blood circulation to restore menstrual flow, removing heat from blood removing blood stasis with potent drugs, and the function of blood stasis removing pain relieving, is used for the treatment of cerebral thrombosis, short treating period, instant effect, non-relapse after healing.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept initial stage cerebral thrombosis out-patient totally 23 examples for medical treatment.
2, diagnostic criteria
Initial symptoms is that extremity do not make strength substantially, dumb, and facial expression is nature not, slight language function obstacle.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 15 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: cerebral thrombosis transference cure, body constitution recovers normal, recovery from illness;
Take a turn for the better: limbs of patient is numb, inarticulateness, and limply symptom alleviates, and cerebral thrombosis symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy cerebral thrombus patient 23 example of the present invention, effective 17 examples of result, obvious effective rate is 73.91%, and take a turn for the better 4 examples, and improvement rate is 17.39%, and invalid 2 examples, total effective rate is 91.31%.

Claims (3)

1. treat a medicine for cerebral thrombosis, it is characterized in that: it is made up of the crude drug in following weight range:
Radix Astragali 15-20 gram, Caulis Spatholobi 10-20 gram, Radix Salviae Miltiorrhizae 15-20 gram, Radix Paeoniae Rubra 10-20 gram, Fructus Ligustri Lucidi 10-15 gram, Radix Ophiopogonis 5-15 gram, Ramulus Uncariae Cum Uncis 10-20 gram, Pheretima 5-15 gram, Herba Taxilli 15-20 gram, Fructus Trichosanthis 10-20 gram, Flos Carthami 7-12 gram, Radix Curcumae 10-20 gram, Radix Angelicae Sinensis 5-15 gram, Rhizoma Chuanxiong 15-20 gram, Radix Glycyrrhizae 7-12 gram, Fructus Lycii 10-20 gram, Spina Gleditsiae 10-20 gram, Myrrha 5-15 gram, Radix Dipsaci 5-15 gram, Radix Saposhnikoviae 10-20 gram, Rhizoma Acori Graminei 5-15 gram, Rhizoma Arisaematis 4-10 gram, Spica Prunellae 10-20 gram, Semen Cassiae 5-15 gram, Caulis Bambusae In Taenia 10-15 gram, Rhizoma Gastrodiae 5-15 gram, Radix Codonopsis 10-15 gram, Radix Polygalae 5-15 gram, Rhizoma Anemarrhenae 7-12 gram, Radix Puerariae 5-15 gram, Rhizoma Pinelliae 5-15 gram, Herba Epimedii 5-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
The Radix Astragali 18 grams, Caulis Spatholobi 15 grams, Radix Salviae Miltiorrhizae 18 grams, Radix Paeoniae Rubra 15 grams, Fructus Ligustri Lucidi 12 grams, Radix Ophiopogonis 10 grams, Ramulus Uncariae Cum Uncis 15 grams, Pheretima 10 grams, Herba Taxilli 18 grams, Fructus Trichosanthis 15 grams, 9 grams, Flos Carthami, Radix Curcumae 15 grams, Radix Angelicae Sinensis 10 grams, Rhizoma Chuanxiong 18 grams, 9 grams, Radix Glycyrrhizae, Fructus Lycii 15 grams, Spina Gleditsiae 15 grams, Myrrha 10 grams, Radix Dipsaci 10 grams, Radix Saposhnikoviae 15 grams, Rhizoma Acori Graminei 10 grams, Rhizoma Arisaematis 8 grams, Spica Prunellae 15 grams, Semen Cassiae 10 grams, Caulis Bambusae In Taenia 12 grams, 10 grams, Rhizoma Gastrodiae, Radix Codonopsis 12 grams, Radix Polygalae 10 grams, the Rhizoma Anemarrhenae 9 grams, Radix Puerariae 10 grams, the Rhizoma Pinelliae 10 grams, Herba Epimedii 15 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
(2) Caulis Spatholobi: run through with water, section, or steam soft after take advantage of fervent sheet, dry;
(3) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(4) Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
(5) Fructus Ligustri Lucidi: pick decontamination, cleans, dries;
(6) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(7) Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
(8) Pheretima: pick decontamination, rinses with water, pulls out in time, dries, cutting;
(9) Herba Taxilli: wash, runs through, and cutting is dried;
(10) Fructus Trichosanthis: get crude drug, removing impurity and fruit stem, clean, and flattens, shredding or fritter, dry;
(11) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(12) Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
(13) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(14) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
(15) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through section, dry;
(16) Fructus Lycii: clean impurity of winnowing with a dustpan, plucks residual stalk and the base of a fruit;
(17) Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;
(18) Myrrha: pick decontamination, breaks into fragment;
(19) Radix Dipsaci: clean silt, removing retained root head, runs through rear section and dries, sieve anti-dandruff;
(20) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(21) Rhizoma Acori Graminei: pick decontamination, cleans, slightly soaks, run through, and section, dries;
(22) Rhizoma Arisaematis: get crude drug, removing impurity, clean ash bits, dry;
(23) Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
(24) Semen Cassiae: get clean Semen Cassiae, putting in pot to fry has fragrance to micro-, takes out, cools;
(25) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;
(26) Rhizoma Gastrodiae: be laid in by Rhizoma Gastrodiae slice and sprayed on the watch core paper of water, put in pot, burns sallow to paper color with slow fire, is constantly stirred by tablet to the strong yellow of two sides;
(27) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(28) Radix Polygalae: pick decontamination, cutting, sieve dedust bits;
(29) Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
(30) Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;
(31) Rhizoma Pinelliae: pick decontamination, sieve dedust bits;
(32) Herba Epimedii: pick clean impurity, destemming, shredding, sieve removes chip;
(2) prepare
(1) Radix Astragali cooked, Caulis Spatholobi, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Fructus Ligustri Lucidi, Radix Ophiopogonis, Ramulus Uncariae Cum Uncis, Pheretima, Herba Taxilli, Fructus Trichosanthis, Flos Carthami, Radix Curcumae, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Glycyrrhizae, Fructus Lycii, Spina Gleditsiae, Myrrha, Radix Dipsaci, Radix Saposhnikoviae, Rhizoma Acori Graminei, Rhizoma Arisaematis, Spica Prunellae, Semen Cassiae, Caulis Bambusae In Taenia, Rhizoma Gastrodiae, Radix Codonopsis, Radix Polygalae, the Rhizoma Anemarrhenae, Radix Puerariae, the Rhizoma Pinelliae, Herba Epimedii are put into decocting container, add water 8 times amount, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring and get final product, 4 doses are divided into take.
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CN107308362A (en) * 2017-06-28 2017-11-03 禹州市合同泰药业有限公司 It is a kind of to treat Chinese medicine composition of cerebral thrombus and preparation method thereof

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CN107308362A (en) * 2017-06-28 2017-11-03 禹州市合同泰药业有限公司 It is a kind of to treat Chinese medicine composition of cerebral thrombus and preparation method thereof

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