CN103263575B - Medicine for treating headache and preparation method thereof - Google Patents
Medicine for treating headache and preparation method thereof Download PDFInfo
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- CN103263575B CN103263575B CN201310212687.0A CN201310212687A CN103263575B CN 103263575 B CN103263575 B CN 103263575B CN 201310212687 A CN201310212687 A CN 201310212687A CN 103263575 B CN103263575 B CN 103263575B
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Abstract
The invention discloses a medicament for treating headache and a preparation method thereof. The medicament is mainly prepared from medicament materials such as frankincense, ligusticum wallichii, asarum, schizonepeta, moutan bark, liquorice, astragalus membranaceus, codonopsis pilosula, peach kernel, carthamus tinctorius L, fructus viticis, rhizoma atractylodis, radix ophiopogonis, chrysanthemum, kudzu vine root, tortoise plastron, cornu cervi degelatinatum and radix asparagi according to certain proportions by weight. The medicament disclosed by the invention has the effects of cleaning heat and drying dampness, nourishing governor meridian, reinforcing qi and nourishing blood, promoting blood circulation to remove meridian, dispersing wind and relieving pain; and headache can be rapidly treated in a short treatment course without reoccurrence.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of headache and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Headache is one of common clinically symptom, typically refers to and is confined to the head first half, comprises the pain at geisoma, helix upper limb and the outer above position of knuckle line of pillow.Headache has gently to be had heavily, and various pain form all can occur, pain also can occur nausea and vomiting phenomenon sometimes, except modal pain, dizzy in addition, heaviness of the head as if it were tightly bandaged, terrified, twitch, beat, or having the sense of note thing, worm climbs sense, the multiple Symptoms such as cranial tinnitus or the unexpected blurred vision of eye.Headache has had a strong impact on people's daily life and work.At present, because Western medicine effectively cannot treat headache, and have certain side effect, therefore, there is very large demand in the Chinese medicine of people to effectively treatment headache.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment headache, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine for the treatment of headache.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Olibanum, Folium Camelliae sinensis, Rhizoma Chuanxiong, Herba Asari, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae, Radix Platycodonis, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Cortex Moutan, Radix Glycyrrhizae, the Radix Astragali, Radix Codonopsis, Semen Persicae, Flos Carthami, Lumbricus, Squama Manis, Semen Vaccariae, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, the Radix Paeoniae Alba, Semen Sinapis Albae, Radix Angelicae Sinensis, Fructus Viticis, Rhizoma Atractylodis, Radix Ophiopogonis, Flos Chrysanthemi, Radix Puerariae, Carapax et Plastrum Testudinis, Cornu Cervi Degelatinatum and Radix Asparagi to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of headache.Wherein select Olibanum to be that temperature, enters the heart, liver, spleen channel, have regulating qi and activating blood, analgesic therapy because its nature and flavor are worked hard, chase after the function of poison, control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select Folium Camelliae sinensis to be that cool, GUIXIN lung stomach warp, has and reduce phlegm, help digestion because its property bitter but sweet flavor, the function of diuresis removing toxic substances, control headache blurred vision, food stagnation expectorant is stagnant, malaria, dysentery.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Select Herba Asari to be that temperature, enters lung, kidney channel, dispel the wind, cold expelling, row water because its nature and flavor are pungent, open the function of stealing, control air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Herba Schizonepetae to be that temperature, enters lung, Liver Channel, deliver, dispel the wind, the function for the treatment of blood disorders because its nature and flavor are pungent, parch to black stops blooding, and cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, and spit blood, epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Select Radix Saposhnikoviae to be because its property acrid-sweet flavor, temperature, enters bladder, lung, spleen channel, delivers, dispel the wind, and victory is wet, and the function of pain relieving, controls affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, anemofrigid-damp arthralgia, and joint is ached, and extremity contraction is anxious, tetanus.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Select Radix Platycodonis to be because its nature and flavor toil, flat, enter lung, stomach warp, have out lung qi dispersing gas, the function of evacuation of pus of eliminating the phlegm, controls exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, and dysentery is suffered from abdominal pain.Select the Radix Angelicae Dahuricae to be that temperature, enters lung, spleen, stomach warp, dispel the wind, dampness because its nature and flavor are pungent, detumescence, the function of pain relieving, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Rhizoma Ligustici is selected to be that temperature, returns urinary bladder channel, have cold expelling to dispel the wind, the function of removing damp and stopping pain because its nature and flavor are pungent, for anemofrigid cold, top, mountain peak pain.Rhizoma Et Radix Notopterygii is selected to be that temperature, enter bladder, kidney channel, have loose exterior cold, wind-damp dispelling, the function in sharp joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore because its nature and flavor are worked hard.Select Radix Angelicae Pubescentis to be that temperature, enters kidney, urinary bladder channel, dispel the wind because its nature and flavor are worked hard, victory is wet, cold expelling, and the function of pain relieving, controls anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle ， Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea ， mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Lumbricus is selected to be because its nature and flavor are salty, cold, enter liver, spleen, lung meridian, have heat clearing away, suppressing the hyperactive liver, Zhichuan, the function of dredging collateral, control high fanatical hot-tempered, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pants, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection.Select Squama Manis to be because its nature and flavor are salty, cool, enter liver, stomach warp, have the routed carbuncle of detumescence, search wind active, the function of stimulating milk secretion of stimulating the menstrual flow, control carbuncle skin ulcer and swell, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external is stopped blooding.Select Semen Vaccariae to be because its nature and flavor hardship is flat, enter liver, stomach warp, have promoting the circulation of blood to stimulate the menstrual flow, expedite the emergence of stimulating milk secretion, the function of detumescence sore, controls women's amenorrhea, galactostasis, and difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have blood circulation and promoting silt, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina cordis, menoxenia, dysmenorrhea, and to close, metrorrhagia leukorrhagia ， mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Rhizoma Cyperi is selected to be because the pungent micro-hard work of its nature and flavor, flat, enter liver, tri-jiao channel, resolving depression of regulating the flow of vital energy, the function of pain relieving regulating menstruation, treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Semen Sinapis Albae to be that temperature, enters lung, stomach warp, have promoting the circulation of QI eliminating phlegm, warming spleen and stomach for dispelling cold, the function of removing obstruction in the collateral to relieve pain, control phlegm retention cough with asthma, fullness and distention in the chest and hypochondrium pain because its nature and flavor are pungent, regurgitation is vomitted, aphasia due to apoplexy, and limbs arthralgia pain is numb, beriberi, carbuncle of yin nature, toxic swelling, treating swelling and pain by traumatic injury.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Fructus Viticis to be because its nature and flavor toil, cool, enter liver, stomach, urinary bladder channel, have dispelling wind and heat pathogens, the function of the clear sharp head, controls anemopyretic cold, just, migraine, and toothache, pain in order eyeball.Rhizoma Atractylodis are selected to be that temperature, enters spleen, stomach warp, have spleen invigorating, dampness, resolving depression, ward off dirty function because its nature and flavor are worked hard, control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Flos Chrysanthemi is selected to be that cool, enter lung, Liver Channel, have dispelling wind, disappear heat, improving eyesight, and the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling because its nature and flavor sweetness and bitterness.Select Radix Puerariae to be that flat, enter spleen, stomach warp, have yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is only drunk, cure the wound cold, cure the wound cold, warm headache stiffness of the nape, dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery because its nature and flavor are sweet pungent, skin eruption is not saturating, hypertension, and angina pectoris is deaf.Select Carapax et Plastrum Testudinis to be because its nature and flavor are salty sweet, flat, enter liver, kidney channel, have YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, the function of strong bone, controls deficiency of kidney yin, hectic fever due to YIN-deficiency consumptive fever, spits blood, epistaxis, chronic cough, seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.Select Cornu Cervi Degelatinatum to be because its nature and flavor are salty, temperature, enter liver, kidney channel, have tonify deficiency, supporing yang function, controls insufficiency of kidney-YANG, ache of the spinal column, Deficiency and coldness of spleen and stomach, vomiting, anorexia and loose stool, deficiency-cold of uterus, bleeding not during menses.Select Radix Asparagi to be because its nature and flavor sweetness and bitterness, cold, enter lung, kidney channel, have YIN nourishing, moisturize, lung heat clearing, the function of pathogenic fire reducing, controls fever due to yin deficiency, and cough is spitted blood, and consumptive lung disease, lung abscess, laryngopharynx swelling and pain, quenches one's thirst, constipation.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Olibanum 8-12 gram of Folium Camelliae sinensis 8-15 gram of Rhizoma Chuanxiong 10-20 gram
Herba Asari 10-20 gram of Herba Schizonepetae 10-20 gram of Radix Saposhnikoviae 10-16 gram
Herba Menthae 6-10 gram of Radix Platycodonis 10-20 gram of Radix Angelicae Dahuricae 10-20 gram
Rhizoma Ligustici 6-10 gram of Rhizoma Et Radix Notopterygii 10-20 gram of Radix Angelicae Pubescentis 8-15 gram
Radix Bupleuri 8-12 gram of Cortex Moutan 10-20 gram of Radix Glycyrrhizae 8-15 gram
Radix Astragali 8-12 gram of Radix Codonopsis 8-10 gram of Semen Persicae 10-16 gram
Flos Carthami 10-20 gram of Lumbricus 6-10 gram of Squama Manis 8-15 gram
Semen Vaccariae 10-20 gram of Radix Salviae Miltiorrhizae 10-16 gram of Rhizoma Cyperi 8-15 gram
Radix Paeoniae Alba 10-20 gram of Semen Sinapis Albae 10-16 gram of Radix Angelicae Sinensis 8-15 gram
Fructus Viticis 10-20 gram Rhizoma Atractylodis 10-16 gram Radix Ophiopogonis 15-25 gram
Flos Chrysanthemi 8-12 gram of Radix Puerariae 15-25 gram of Carapax et Plastrum Testudinis 8-15 gram
Cornu Cervi Degelatinatum 6-12 gram of Radix Asparagi 10-20 gram
Wherein, be preferably
Olibanum 10 grams of Folium Camelliae sinensis 10 grams of Rhizoma Chuanxiongs 15 grams
Herba Asari 15 grams of Herba Schizonepetae 16 grams of Radix Saposhnikoviaes 12 grams
Herba Menthae 8 grams of Radix Platycodoniss 15 grams of Radixs Angelicae Dahuricae 15 grams
Rhizoma Ligustici 8 grams of Rhizoma Et Radix Notopterygiis 16 grams of Radix Angelicae Pubescentiss 12 grams
12 grams, Radix Bupleuri 10 grams of Cortex Moutans 16 grams of Radix Glycyrrhizaes
12 grams, the Radix Astragali 10 grams of Radix Codonopsis 12 grams of Semen Persicaes
Flos Carthami 16 grams of Lumbricuss 8 grams of Squama Maniss 10 grams
Semen Vaccariae 16 grams of Radix Salviae Miltiorrhizaes 12 grams of Rhizoma Cyperis 12 grams
The Radix Paeoniae Alba 16 grams of Semen Sinapis Albaes 12 grams of Radix Angelicae Sinensis 12 grams
Fructus Viticis 16 grams of Rhizoma Atractylodis 12 grams of Radix Ophiopogonis 20 grams
Flos Chrysanthemi 10 grams of Radix Puerariaes 20 grams of Carapax et Plastrum Testudiniss 12 grams
Cornu Cervi Degelatinatum 10 grams of Radix Asparagi 18 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Olibanum: pick shakeout, impurity;
2, Folium Camelliae sinensis: plucked before grain rains, after fresh leaf gathers, through completing, kneads, dry;
3, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
4, Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;
5, Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;
6, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
7, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
8, Radix Platycodonis: pick clean impurity, except removing LU, cleans and pulls out, run through rear section, dry;
9, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
10, Rhizoma Ligustici: get crude drug, removing impurity, size stepping, wash quickly is clean, runs through, and section, dries;
11, Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
12, Radix Angelicae Pubescentis: pick decontamination, separately size, clean, run through rear section, dry;
13, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
14, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
15, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
16, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
17, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
18, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
19, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
20, Lumbricus: pick decontamination, rinses with water, pulls out in time, dries, cutting;
21, Squama Manis: get the Squama Manis sheet picking clean, separately size, separately put sand in pot and fry to easily, add Squama Manis sheet, frying to heaving in time golden yellow, taking out, and sieve shakeout, cools;
22, Semen Vaccariae: clean impurity of winnowing with a dustpan, puts in pot, takes out, cool when frying to spend six, seventy percent to popping in vain with slow fire;
23, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
24, Rhizoma Cyperi: pick decontamination, is ground into particle, winnow with a dustpan fine, soft fur and smalls;
25, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
26, Semen Sinapis Albae: former medicine is winnowed with a dustpan most impurity, and fry to buff, micro-have fragrance and get final product;
27, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;
28, Fructus Viticis: well sifted ash bits, remove remaining sepal, put in pot and fry with high heat to coke yellow, slightly spray clear water, cool;
29, Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
30, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
31, Flos Chrysanthemi: pick clean leaf stalk, anthocaulus and spare impurity;
32, Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;
33, Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, cleans, dries, knock fritter;
34, Cornu Cervi Degelatinatum: pick decontamination, hacks into fritter;
35, Radix Asparagi: pick decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, dry.
Two, prepare
1, the Olibanum of described weight, Folium Camelliae sinensis, Rhizoma Chuanxiong, Herba Asari, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae, Radix Platycodonis, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Cortex Moutan, Radix Glycyrrhizae, the Radix Astragali, Radix Codonopsis, Semen Persicae, Flos Carthami, Lumbricus, Squama Manis, Semen Vaccariae, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, the Radix Paeoniae Alba, Semen Sinapis Albae, Radix Angelicae Sinensis, Fructus Viticis, Rhizoma Atractylodis, Radix Ophiopogonis, Flos Chrysanthemi, Radix Puerariae, Carapax et Plastrum Testudinis, Cornu Cervi Degelatinatum, Radix Asparagi are decocted with water, add water 5 times amount for the first time, soak 200 minutes, intense fire decocts boiling 35 minutes, use slow fire boiling again 20 minutes, obtain first time decoction liquor.
2, add water medicinal residues after first time filtration 3 times amount, decocts boiling, then within 20 minutes, namely obtain second time decoction liquor with slow fire boiling.
3, by twice decoction liquor mixing, then use slow fire boiling 15 minutes, liquid will be boiled and be divided into 4 doses.
Medicine of the present invention has heat clearing and damp drying, warm dredging DU Meridian arteries and veins, benefiting QI and nourishing blood, promoting blood circulation to remove obstruction in the collateral, effect of loose wind pain relieving, and treatment headache instant effect, short treating period, does not recur, and cure rate is high.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 20, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 10, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient 200 example for medical treatment, wherein chronic headache 120 example, acute headache 80 example.
2, diagnostic criteria
Chronic headache: chronic headache (chronic daily headache) is called for short CHD, refer to that the frequent outbreak of headache is monthly more than 15 days, every day, headache continued more than 4 hours.Slow onset, or recurrent exerbation, time pain time only.
Acute headache: break out, can with headache, stiffness of the nape, nausea and vomiting, unrelenting headache sharply, with disturbance of consciousness in various degree, and headache companion hyperemesis, long-term intermittent outbreak headache.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, acute patient is each serving with 1 dose, and every day is early, middle and late respectively takes 1 time, within 10 days, is a course for the treatment of, takes three courses for the treatment of continuously.Chronic patients is each serving with 1 dose, and every day is early, middle and late respectively takes 1 time, within 10 days, is a course for the treatment of, takes six courses for the treatment of continuously.
4, efficacy assessment standard
Effective: clinical symptom disappearance after treatment, headache recovery from illness, body constitution recovers normal, observes half a year without recidivist;
Take a turn for the better: clinical symptoms is obviously improved, and headache alleviates, and body constitution is progressively recovered;
Invalid: clinical part transference cure or without change, do not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy headache 200 example of the present invention, wherein chronic patients 120 example, effective 110 examples of result, obvious effective rate is 91.67%, and take a turn for the better 7 examples, and improvement rate is 5.83%, and invalid 3 examples, total effective rate is 97.5%.Patients with mild 80 example, effective 74 examples of result, obvious effective rate is 92.5%, and take a turn for the better 5 examples, and improvement rate is 6.25%, and invalid 1 example, total effective rate is 98.57%.
Claims (3)
1. treat a medicine for headache, it is characterized in that: it is made up of the crude drug in following weight range:
Olibanum 8-12 gram of Folium Camelliae sinensis 8-15 gram of Rhizoma Chuanxiong 10-20 gram
Herba Asari 10-20 gram of Herba Schizonepetae 10-20 gram of Radix Saposhnikoviae 10-16 gram
Herba Menthae 6-10 gram of Radix Platycodonis 10-20 gram of Radix Angelicae Dahuricae 10-20 gram
Rhizoma Ligustici 6-10 gram of Rhizoma Et Radix Notopterygii 10-20 gram of Radix Angelicae Pubescentis 8-15 gram
Radix Bupleuri 8-12 gram of Cortex Moutan 10-20 gram of Radix Glycyrrhizae 8-15 gram
Radix Astragali 8-12 gram of Radix Codonopsis 8-10 gram of Semen Persicae 10-16 gram
Flos Carthami 10-20 gram of Lumbricus 6-10 gram of Squama Manis 8-15 gram
Semen Vaccariae 10-20 gram of Radix Salviae Miltiorrhizae 10-16 gram of Rhizoma Cyperi 8-15 gram
Radix Paeoniae Alba 10-20 gram of Semen Sinapis Albae 10-16 gram of Radix Angelicae Sinensis 8-15 gram
Fructus Viticis 10-20 gram Rhizoma Atractylodis 10-16 gram Radix Ophiopogonis 15-25 gram
Flos Chrysanthemi 8-12 gram of Radix Puerariae 15-25 gram of Carapax et Plastrum Testudinis 8-15 gram
Cornu Cervi Degelatinatum 6-12 gram of Radix Asparagi 10-20 gram.
2. treat a medicine for headache, wherein the consumption of each crude drug is:
Olibanum 10 grams of Folium Camelliae sinensis 10 grams of Rhizoma Chuanxiongs 15 grams
Herba Asari 15 grams of Herba Schizonepetae 16 grams of Radix Saposhnikoviaes 12 grams
Herba Menthae 8 grams of Radix Platycodoniss 15 grams of Radixs Angelicae Dahuricae 15 grams
Rhizoma Ligustici 8 grams of Rhizoma Et Radix Notopterygiis 16 grams of Radix Angelicae Pubescentiss 12 grams
12 grams, Radix Bupleuri 10 grams of Cortex Moutans 16 grams of Radix Glycyrrhizaes
12 grams, the Radix Astragali 10 grams of Radix Codonopsis 12 grams of Semen Persicaes
Flos Carthami 16 grams of Lumbricuss 8 grams of Squama Maniss 10 grams
Semen Vaccariae 16 grams of Radix Salviae Miltiorrhizaes 12 grams of Rhizoma Cyperis 12 grams
The Radix Paeoniae Alba 16 grams of Semen Sinapis Albaes 12 grams of Radix Angelicae Sinensis 12 grams
Fructus Viticis 16 grams of Rhizoma Atractylodis 12 grams of Radix Ophiopogonis 20 grams
Flos Chrysanthemi 10 grams of Radix Puerariaes 20 grams of Carapax et Plastrum Testudiniss 12 grams
Cornu Cervi Degelatinatum 10 grams of Radix Asparagi 18 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Olibanum: pick shakeout, impurity;
(2) Folium Camelliae sinensis: plucked before grain rains, after fresh leaf gathers, through completing, kneads, dry;
(3) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
(4) Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;
(5) Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;
(6) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(7) Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;
(8) Radix Platycodonis: pick clean impurity, except removing LU, cleans and pulls out, run through rear section, dry;
(9) Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
(10) Rhizoma Ligustici: get crude drug, removing impurity, size stepping, wash quickly is clean, runs through, and section, dries;
(11) Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
(12) Radix Angelicae Pubescentis: pick decontamination, separately size, clean, run through rear section, dry;
(13) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
(14) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(15) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
(16) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
(17) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(18) Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
(19) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(20) Lumbricus: pick decontamination, rinses with water, pulls out in time, dries, cutting;
(21) Squama Manis: get the Squama Manis sheet picking clean, separately size, separately put sand in pot and fry to easily, add Squama Manis sheet, frying to heaving in time golden yellow, taking out, and sieve shakeout, cools;
(22) Semen Vaccariae: clean impurity of winnowing with a dustpan, puts in pot, takes out, cool when frying to spend six, seventy percent to popping in vain with slow fire;
(23) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(24) Rhizoma Cyperi: pick decontamination, is ground into particle, winnow with a dustpan fine, soft fur and smalls;
(25) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(26) Semen Sinapis Albae: former medicine is winnowed with a dustpan most impurity, and fry to buff, micro-have fragrance and get final product;
(27) Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;
(28) Fructus Viticis: well sifted ash bits, remove remaining sepal, put in pot and fry with high heat to coke yellow, slightly spray clear water, cool;
(29) Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
(30) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(31) Flos Chrysanthemi: pick clean leaf stalk, anthocaulus and spare impurity;
(32) Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;
(33) Carapax et Plastrum Testudinis: soak with clear water, scrape off residual meat, cleans, dries, knock fritter;
(34) Cornu Cervi Degelatinatum: pick decontamination, hacks into fritter;
(35) Radix Asparagi: pick decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, dry;
(2) prepare
(1) Olibanum of described weight, Folium Camelliae sinensis, Rhizoma Chuanxiong, Herba Asari, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae, Radix Platycodonis, the Radix Angelicae Dahuricae, Rhizoma Ligustici, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Bupleuri, Cortex Moutan, Radix Glycyrrhizae, the Radix Astragali, Radix Codonopsis, Semen Persicae, Flos Carthami, Lumbricus, Squama Manis, Semen Vaccariae, Radix Salviae Miltiorrhizae, Rhizoma Cyperi, the Radix Paeoniae Alba, Semen Sinapis Albae, Radix Angelicae Sinensis, Fructus Viticis, Rhizoma Atractylodis, Radix Ophiopogonis, Flos Chrysanthemi, Radix Puerariae, Carapax et Plastrum Testudinis, Cornu Cervi Degelatinatum, Radix Asparagi are decocted with water, add water 5 times amount for the first time, soak 200 minutes, intense fire decocts boiling 35 minutes, use slow fire boiling again 20 minutes, obtain first time decoction liquor;
(2) add water medicinal residues after first time filtration 3 times amount, decocts boiling, then within 20 minutes, namely obtain second time decoction liquor with slow fire boiling;
(3) by twice decoction liquor mixing, then use slow fire boiling 15 minutes, liquid will be boiled and be divided into 4 doses.
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