CN103638399B

CN103638399B - A kind of medicine for the treatment of Child epidemic parotitis and preparation method thereof

Info

Publication number: CN103638399B
Application number: CN201310662553.9A
Authority: CN
Inventors: 张朝兰
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-12-10
Filing date: 2013-12-10
Publication date: 2015-09-23
Anticipated expiration: 2033-12-10
Also published as: CN103638399A

Abstract

The invention discloses a kind of medicine for the treatment of Child epidemic parotitis and preparation method thereof, it is mainly prepared from according to a certain weight ratio by medicines such as Fructus Arctii, Folium Isatidis, Herba Taraxaci, Rhizoma Phragmitis, Squama Manis, Radix Puerariae, Herba Menthae, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Gypsum Fibrosum, medicine of the present invention has heat-clearing and toxic substances removing, Qingfei Liangxue, the function of wind-dispelling heat-dissipating, be used for the treatment of Child epidemic parotitis instant effect, good effect, do not recur.

Description

A kind of medicine for the treatment of Child epidemic parotitis and preparation method thereof

Technical field

The present invention relates to a kind of medicine being used for the treatment of Child epidemic parotitis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Infantile parotitis is the Acute respiratory infectious disease caused by mumps virus, is mainly in child, in sporadic popular, can form outbreak of epidemic in collective children mechanism.Clinical with the swelling of salivary gland acute nonsuppurative for special disease, often occur together meningitis, pancreatitis and orchitis etc.At present, western medicine Child epidemic parotitis poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of effectively treating Child epidemic parotitis in people.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment Child epidemic parotitis, thus completes the present invention.

Object of the present invention is just to provide a kind of composition of medicine effectively can treating Child epidemic parotitis.

Another object of the present invention just there is provided the preparation method of this composition of medicine.

Medicine of the present invention selects Fructus Arctii, Folium Isatidis, Herba Taraxaci, Rhizoma Phragmitis, Squama Manis, Radix Puerariae, Herba Menthae, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Gypsum Fibrosum, Fructus Arctii, Radix Platycodonis, Semen Persicae, Herba Asari, Radix Et Rhizoma Rhei, Lasiosphaera Seu Calvatia, Bombyx Batryticatus, Mirabilitum crystallina, Fructus Gardeniae, Herba Commelinae, Semen Litchi, Radix Gentianae, Radix Scrophulariae, Semen oryzae sativae, Herba Violae, Indigo Naturalis, Rhizoma Imperatae, Caulis Lonicerae, Sargassum, Radix Trichosanthis, Caulis Trachelospermi, the Rhizoma Anemarrhenae, Herba Schizonepetae, Folium Hibisci Mutabilis medicine to combine, each efficacy of drugs is made by these drug regimens to produce synergism, thus can the recurrence of fast treating Child epidemic parotitis.Wherein select Fructus Arctii to be that cool, enter lung, stomach warp, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating, controls cough due to pathogenic wind-heat, laryngopharynx swelling and pain because its nature and flavor are worked hard, macule is not saturating, and rubella is had an itch, carbuncle sore tumefacting virus.Folium Isatidis is selected to be because its nature and flavor are bitter, cold, enter liver, the heart, stomach warp, have heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Rhizoma Phragmitis is selected to be that cold, enter lung, stomach warp, has heat clearing away, promotes the production of body fluid, relieving restlessness, and the function of preventing or arresting vomiting controls calentura excessive thirst, gastropyretic vomiting, dysphagic, regurgitation, consumptive lung disease, lung abscess, and separates Fugu ocellatus ichthyotoxin because its nature and flavor are sweet.Select Squama Manis to be because its nature and flavor are salty, cool, enter liver, stomach warp, have the routed carbuncle of detumescence, search wind active, the function of stimulating milk secretion of stimulating the menstrual flow, control carbuncle skin ulcer and swell, anemofrigid-damp arthralgia, amenorrhea, galactostasis, external is stopped blooding.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, have yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is quenched the thirst, cure the wound cold, warm, headache, stiffness of the nape, dysphoria with smothery sensation disappears and drinks, and has loose bowels, dysentery, and abnormal pigmentary deposit on the skin is examined not saturating, hypertension, and angina pectoris is deaf.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Select Rhizoma Smilacis Glabrae to be because its property slightly sweet flavor, flat, enter liver, stomach warp, have removing toxic substances, dehumidifying, the function in sharp joint, controls syphilis, stranguria with turbid discharge, muscles and bones spasm and pain, beriberi, furuncle, carbuncle, scrofula.Select Rhizoma Polygoni Cuspidati to be because its nature and flavor are bitter, flat, dispel the wind, dampness removing, removing blood stasis with potent drugs, the function of stimulating the menstrual flow, dispelling the wind and dampness pathogens bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis ， lumps in the chest and abdomen, anal fistula hematochezia, injury from falling down, scalds, malignant boil tinea disease.Gypsum Fibrosum is selected to be because its property acrid-sweet flavor, cold, enter lung, stomach warp, raw with there being expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst, controls calentura high fever and does not move back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, forges deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, bursts and does not regain, the burning hot wound of soup.Select Fructus Arctii to be that cool, enter lung, stomach warp, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating, controls cough due to pathogenic wind-heat, laryngopharynx swelling and pain because its nature and flavor are worked hard, macule is not saturating, and rubella is had an itch, carbuncle sore tumefacting virus.Select Radix Platycodonis to be because its nature and flavor toil, flat, enter lung, stomach warp, have out lung qi dispersing gas, the function of evacuation of pus of eliminating the phlegm, controls exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, and dysentery is suffered from abdominal pain.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select Herba Asari to be that temperature, enters lung, kidney channel, dispel the wind, cold expelling, row water because its nature and flavor are pungent, open the function of stealing, control air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Radix Et Rhizoma Rhei is selected to be that enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant because its nature and flavor are bitter, cold, the function of clots absorbing blood, control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Lasiosphaera Seu Calvatia is selected to be because its nature and flavor are pungent, flat.Enter lung meridian.Removing heat from the lung and relieving sorethroat, removing toxic substances, hemostasis.Control sore throat pharyngalgia, cough with aphonia, spit blood, epistaxis, traumatic hemorrhage.Bombyx Batryticatus is selected to be because its nature and flavor are pungent, salty, flat.Return liver, lung meridian.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.For apoplexy facial hemiparalysis, infantile convulsion is twitched, and head is grant, sore throat, scrofula tuberculosis, rubella erysipelas.Mirabilitum crystallina is selected to be because its nature and flavor are pungent salty, cold, enter the heart, stomach, kidney channel, have resolving heat and reducing pathogenic fire, sharp key, the function of detumescence, row calentura when controlling, accumulated heat excessive thirst, vomit and diarrhoea, edema, urine retention, bleeding from the gum, erysipelas, scald.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, have heat clearing away, pathogenic fire purging, the function of removing heat from blood, control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Herba Commelinae is selected to be because its nature and flavor are sweet, cold, there is heat clearing away, removing heat from blood, the function of removing toxic substances, harness the river swollen, beriberi, dysuria, treat laryngopharynx swelling and pain, malaria, hematodiarrhoea.Select Semen Litchi to be because its property sweet-puckery flavor, temperature, enter liver, kidney channel, have warming middle-JIAO, regulate the flow of vital energy, the function of pain relieving, controls gastric abscess, colicky, women's pricking caused by the stagnation of QI and blood.Select Radix Gentianae to be that cold, enter liver, gallbladder meridian, have eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B because its nature and flavor are bitter, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.Select Radix Scrophulariae to be because its nature and flavor hardship is salty, cool, enter lung, kidney channel, have YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances, control calentura excessive thirst, send out speckle, hectic fever due to YIN-deficiency consumptive fever, sleep night not peaceful, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Semen oryzae sativae is selected to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, have invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, relieving thirst and restlessness, antidiarrheal dysentery.Select Herba Violae to be that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because its nature and flavor bitter, acrid, cold, the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Select Indigo Naturalis to be because its nature and flavor are salty, cold, enter liver, lung, stomach warp, have heat clearing away, removing heat from blood, the function of removing toxic substances, control epidemic febrile disease intenseness of heat, macule, spit blood, spit blood, little Jing Epilepsy, skin ulcer swells, erysipelas, snake bite and insect sting.Select Rhizoma Imperatae to be sweet because of its nature and flavor, cold, enter lung, stomach, small intestine meridian, have removing heat from blood, hemostasis, heat clearing away, the function of diuresis, controls calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Caulis Lonicerae is selected to be because its nature and flavor are sweet, cold, enter the heart, lung meridian, have heat clearing away, removing toxic substances, the function of dredging collateral, control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.Sargassum is selected to be that cold, enter lung, spleen, kidney channel, have softening the hard mass, expectorant, diuretic, the function expelled the heat-evil, controls scrofula, and goiter is gathered, edema, beriberi, painful and swollen testis because its nature and flavor hardship is salty.Radix Trichosanthis is selected to be that cool, enter lung, stomach warp, have and promote the production of body fluid, quench the thirst, pathogenic fire reducing, moisturize, evacuation of pus, the function of detumescence, controls calentura thirsty, quenches one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula because its nature and flavor sweetness and bitterness acid.Caulis Trachelospermi is selected to be because its nature and flavor are bitter, cool, enter liver, kidney channel, dispel the wind, dredging collateral, hemostasis, the function of repercussive, dispelling the wind and dampness pathogens arthralgia pain, the contracture of muscle arteries and veins, carbuncle, sore throat, spit blood, traumatic injury, disease that postpartum lochia can't go.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Herba Schizonepetae to be that temperature, enters lung, Liver Channel, deliver, dispel the wind, the function for the treatment of blood disorders because its nature and flavor are pungent, parch to black stops blooding, and cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, and spit blood, epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Select Folium Hibisci Mutabilis to be because its nature and flavor are micro-pungent, cool, return lung, Liver Channel, have Qingfei Liangxue, heat radiation removing toxic substances, the function of detumescence and apocenosis, controls cough due to lung-heat, acute appendicitis, external treatment carbuncle, glue ear, innominate toxic swelling, burn.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Fructus Arctii 5-15 gram of Folium Isatidis 10-20 gram of Herba Taraxaci 10-20 gram

Rhizoma Phragmitis 10-20 gram of Squama Manis 5-15 gram of Radix Puerariae 5-15 gram

Herba Menthae 5-15 gram of Rhizoma Smilacis Glabrae 10-20 gram of Rhizoma Polygoni Cuspidati 10-20 gram

Gypsum Fibrosum 10-20 gram of Fructus Arctii 5-15 gram of Radix Platycodonis 10-20 gram

Semen Persicae 10-20 gram of Herba Asari 10-20 gram of Radix Et Rhizoma Rhei 5-15 gram

Lasiosphaera Seu Calvatia 5-15 gram of Bombyx Batryticatus 5-15 gram of Mirabilitum crystallina 5-15 gram

Fructus Gardeniae 5-15 gram of Herba Commelinae 8-15 gram of Semen Litchi 3-9 gram

Radix Gentianae 8-15 gram of Radix Scrophulariae 25-35 gram of Semen oryzae sativae 5-15 gram

Herba Violae 10-20 gram Indigo Naturalis 15-25 gram Rhizoma Imperatae 20-30 gram

Caulis Lonicerae 5-15 gram of Sargassum 5-15 gram of Radix Trichosanthis 3-9 gram

Caulis Trachelospermi 10-20 gram of Rhizoma Anemarrhenae 5-15 gram of Herba Schizonepetae 10-20 gram

Folium Hibisci Mutabilis 5-15 gram

Preferable amount is

Fructus Arctii 10 grams of Folium Isatidiss 15 grams of Herba Taraxacis 15 grams

Rhizoma Phragmitis 15 grams of Squama Maniss 10 grams of Radix Puerariaes 10 grams

Herba Menthae 10 grams of Rhizoma Smilacis Glabraes 15 grams of Rhizoma Polygoni Cuspidati 15 grams

Gypsum Fibrosum 15 grams of Fructus Arctiis 10 grams of Radix Platycodoniss 15 grams

Semen Persicae 15 grams of Herba Asaris 15 grams of Radix Et Rhizoma Rhei 10 grams

Lasiosphaera Seu Calvatia 10 grams of Bombyx Batryticatus 10 grams of Mirabilitum crystallinas 10 grams

Fructus Gardeniae 10 grams of Herba Commelinaes 10 grams of Semen Litchis 6 grams

Radix Gentianae 10 grams of Radix Scrophulariaes 30 grams of Semen oryzae sativaes 10 grams

Herba Violae 15 grams of Indigo Naturaliss 20 grams of Rhizoma Imperataes 25 grams

Caulis Lonicerae 10 grams of Sargassums 10 grams of Radix Trichosanthis 6 grams

Caulis Trachelospermi 15 grams of Rhizoma Anemarrhenaes 10 grams of Herba Schizonepetae 15 grams

Folium Hibisci Mutabilis 10 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Fructus Arctii: pick decontamination, sieve removes spare;

2, Folium Isatidis: pick decontamination and dead leaf, cleans, slightly moistens, cutting, dry;

3, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;

4, Rhizoma Phragmitis: pick decontamination and root, cutting, dry;

5, Squama Manis: get the Squama Manis sheet picking clean, separately size, separately puts sand in pot and makes popular, add Squama Manis sheet, frying to heaving in time golden yellow, taking out, and sieve shakeout, cools;

6, Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;

7, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;

8, Rhizoma Smilacis Glabrae: with water logging drift, change water every day in summer 1 time, spring, every 2 days of autumn change water 1 time, and winter can change water on the 3rd 1 time, prevents smelly, to soak as degree, pull section out, dry in time;

9, Rhizoma Polygoni Cuspidati: adopt after polygoni cuspidati,radix, smooth file, wraps up in a night with Folium Polygoni Cuspidati, dries;

10, Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter;

11, Fructus Arctii: pick decontamination, sieve removes spare;

12, Radix Platycodonis: pick clean impurity, except removing LU, cleans and pulls out, run through rear section, dry;

13, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;

14, Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;

15, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;

16, Lasiosphaera Seu Calvatia: removing sclerderm, dice;

17, Bombyx Batryticatus: get crude drug, removes residual silk, impurity;

18, Mirabilitum crystallina: get crude drug, removing impurity, cleaning, drying, break into fragment;

19, Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve or cut off two ends;

20, Herba Commelinae: pick decontamination, cleans, and cuts off, dries;

21, Semen Litchi: get crude drug, removing impurity, the used time smashs to pieces;

22, Radix Gentianae: pick decontamination, removes residual stem, cleans, runs through rear cutting, dry;

23, Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;

24, Semen oryzae sativae: clean chip of winnowing with a dustpan, dries;

25, Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;

26, Indigo Naturalis: pick decontamination, sieves;

27, Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;

28, Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;

29, Sargassum: pick decontamination, with water slightly drift, slightly dry in the air, cutting, dries;

30, Radix Trichosanthis: pick decontamination, size block is separately, saturating with blister about sixty percent, pulls out, and moistening is even to inside and outside humidity, and section, dries, or wash, pull out, shine extremely dry, be pounded fritter;

31, Caulis Trachelospermi: wash earth with water, picks clean impurity, slightly soaks, run through, and cuts off, dries;

32, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;

33, Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;

34, Folium Hibisci Mutabilis: the residual branch stalk of removing, impurity, with Water spray, slightly moistens, shredding, dry.

Two, prepare

1, by the Fructus Arctii of described weight, Folium Isatidis, Herba Taraxaci, Rhizoma Phragmitis, Squama Manis, Radix Puerariae, Herba Menthae, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Gypsum Fibrosum, Fructus Arctii, Radix Platycodonis, Semen Persicae, Herba Asari, Radix Et Rhizoma Rhei, Lasiosphaera Seu Calvatia, Bombyx Batryticatus, Mirabilitum crystallina, Fructus Gardeniae, Herba Commelinae, Semen Litchi, Radix Gentianae, Radix Scrophulariae, Semen oryzae sativae, Herba Violae, Indigo Naturalis, Rhizoma Imperatae, Caulis Lonicerae, Sargassum, Radix Trichosanthis, Caulis Trachelospermi, the Rhizoma Anemarrhenae, Herba Schizonepetae, Folium Hibisci Mutabilis medicine decocts with water secondary, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 35 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.

2, add water medicinal residues after first time filtration 5 times amount, decocts boiling, then use slow fire boiling 20 minutes, filter and to obtain second time decoction liquor.

3,6 doses are divided into take twice decoction liquor mixing.

Medicine of the present invention has heat-clearing and toxic substances removing, Qingfei Liangxue, effect of wind-dispelling heat-dissipating, is used for the treatment of Child epidemic parotitis instant effect, short treating period, does not recur.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The observations of [test example 2] Drug therapy Child epidemic parotitis of the present invention

1, physical data

Accept Child epidemic parotitis patient totally 148 examples for medical treatment.

2, diagnostic criteria

Clinical manifestation

1. incubation period is 2 ~ 3 weeks, average 18 days.

2. it is very short to show prodromal period prodromal period, a few hours to 1 ~ 2 day.Often there are heating, inappetence, general weakness, headache, vomiting etc.The degree of heat not etc., does not also have the normal person of body temperature., can meningismus be there is in the early stage incidence of meningitis of minority infant.

3. the parotid gland swells phase parotid gland enlargement prior to side, then opposite side also enlargement, also has only side enlargement or the parotid gland without the case of enlargement.The feature of enlargement is centered by ear-lobe, expands towards periphery, blur margin, and the flexible sense of touching and tenderness, surface skin is not rubescent.Swelling scope upper limb can reach the jugal bridge, and trailing edge reaches sternocleidomastoid, under lower edge extends to jaw, reaches cervical region.Mumps reaches peak in about 3 ~ 5 days, and convergent disappears for little general about 1 week then, is occasionally extended down to 2 weeks persons.Sometimes submaxillary gland and sublingual gland all can enlargements, and be common with the former enlargement, some case only has submaxillary gland enlargement and the parotid gland is little.Part infant submaxillary gland, sublingual gland and the parotid gland all the time without obvious tumefaction, and can only have the performance of viremia or complication.Orifice of parotid duct is red and swollen as seen.Infant feels parotid gland local distending pain and hyperesthesia, more obvious when dehiscing and chew.While parotid gland enlargement, body temperature is still high, but the degree that increases of body temperature and the length of persistent period and parotid gland enlargement degree have nothing to do.Heating continuing time differs, and short person 1 ~ 2 day, minority can reach 2 weeks.Generate heat common with medium degree, low grade fever and high heat all rare, about 20% body temperature is normal all the time.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.

4, efficacy assessment standard

Effective: Child epidemic parotitis transference cure, observe 1 year without bounce-back person;

Take a turn for the better: Child epidemic parotitis symptom is obviously improved, and body constitution progressively strengthens;

Invalid: Child epidemic parotitis symptom, without change, does not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, by Drug therapy Child epidemic parotitis patient 148 example of the present invention, effective 141 examples of result, obvious effective rate is 95.27%, and take a turn for the better 5 examples, and improvement rate is 3.38%, and invalid 2 examples, total effective rate is 98.65%.

Claims

1. treat a medicine for Child epidemic parotitis, it is characterized in that: it is made up of the crude drug in following weight range:

Gypsum Fibrosum 10-20 gram of Radix Platycodonis 10-20 gram of Semen Persicae 10-20 gram

The Herba Asari 10-20 gram of vigorous 5-15 gram of Radix Et Rhizoma Rhei 5-15 Rana nigromaculata

Bombyx Batryticatus 5-15 gram of Mirabilitum crystallina 5-15 gram of Fructus Gardeniae 5-15 gram

Herba Commelinae 8-15 gram of Semen Litchi 3-9 cron gallbladder 8-15 gram

Radix Scrophulariae 25-35 gram of Semen oryzae sativae 5-15 gram of Herba Violae 10-20 gram

Indigo Naturalis 15-25 gram of Rhizoma Imperatae 20-30 gram of Caulis Lonicerae 5-15 gram

Sargassum 5-15 gram of Radix Trichosanthis 3-9 gram of Caulis Trachelospermi 10-20 gram

Rhizoma Anemarrhenae 5-15 gram of Herba Schizonepetae 10-20 gram of Folium Hibisci Mutabilis 5-15 gram

Fructus Arctii 5-15 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

15 grams, Gypsum Fibrosum 15 grams of Radix Platycodoniss 15 grams of Semen Persicaes

Vigorous 10 grams of Herba Asari 15 grams of Radix Et Rhizoma Rhei 10 Rana nigromaculata

Bombyx Batryticatus 10 grams of Mirabilitum crystallinas 10 grams of Fructus Gardeniaes 10 grams

10 grams, Herba Commelinae 10 grams of Semen Litchi 6 cron gallbladders

Radix Scrophulariae 30 grams of Semen oryzae sativaes 10 grams of Herba Violaes 15 grams

Indigo Naturalis 20 grams of Rhizoma Imperataes 25 grams of Caulis Loniceraes 10 grams

Sargassum 10 grams of Radix Trichosanthis 6 grams of Caulis Trachelospermis 15 grams

The Rhizoma Anemarrhenae 10 grams of Herba Schizonepetae 15 grams of Folium Hibisci Mutabiliss 10 grams

Fructus Arctii 10 grams.

3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) Fructus Arctii: pick decontamination, sieve removes spare;

(2) Folium Isatidis: pick decontamination and dead leaf, cleans, slightly moistens, cutting, dry;

(3) Herba Taraxaci: pick decontamination, clean earth, cutting, dries;

(4) Rhizoma Phragmitis: pick decontamination and root, cutting, dry;

(5) Squama Manis: get the Squama Manis sheet picking clean, separately size, separately puts sand in pot and makes popular, add Squama Manis sheet, frying to heaving in time golden yellow, taking out, and sieve shakeout, cools;

(6) Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;

(7) Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;

(8) Rhizoma Smilacis Glabrae: with water logging drift, change water every day in summer 1 time, spring, every 2 days of autumn change water 1 time, and winter can change water on the 3rd 1 time, prevents smelly, to soak as degree, pull section out, dry in time;

(9) Rhizoma Polygoni Cuspidati: adopt after polygoni cuspidati,radix, smooth file, wraps up in a night with Folium Polygoni Cuspidati, dries;

(10) Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter;

(11) Radix Platycodonis: pick clean impurity, except removing LU, cleans and pulls out, run through rear section, dry;

(12) Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;

(13) Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;

(14) Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;

(15) Lasiosphaera Seu Calvatia: removing sclerderm, dice;

(16) Bombyx Batryticatus: get crude drug, removes residual silk, impurity;

(17) Mirabilitum crystallina: get crude drug, removing impurity, cleaning, drying, break into fragment;

(18) Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve or cut off two ends;

(19) Herba Commelinae: pick decontamination, cleans, and cuts off, dries;

(20) Semen Litchi: get crude drug, removing impurity, the used time smashs to pieces;

(21) Radix Gentianae: pick decontamination, removes residual stem, cleans, runs through rear cutting, dry;

(22) Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;

(23) Semen oryzae sativae: clean chip of winnowing with a dustpan, dries;

(24) Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;

(25) Indigo Naturalis: pick decontamination, sieves;

(26) Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;

(27) Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;

(28) Sargassum: pick decontamination, with water slightly drift, slightly dry in the air, cutting, dries;

(29) Radix Trichosanthis: pick decontamination, size block is separately, saturating with blister about sixty percent, pulls out, and moistening is even to inside and outside humidity, and section, dries, or wash, pull out, shine extremely dry, be pounded fritter;

(30) Caulis Trachelospermi: wash earth with water, picks clean impurity, slightly soaks, run through, and cuts off, dries;

(31) Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;

(32) Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;

(33) Folium Hibisci Mutabilis: the residual branch stalk of removing, impurity, with Water spray, slightly moistens, shredding, dry;

(2) prepare

(1) by the Fructus Arctii of described weight, Folium Isatidis, Herba Taraxaci, Rhizoma Phragmitis, Squama Manis, Radix Puerariae, Herba Menthae, Rhizoma Smilacis Glabrae, Rhizoma Polygoni Cuspidati, Gypsum Fibrosum, Radix Platycodonis, Semen Persicae, Herba Asari, Radix Et Rhizoma Rhei, Lasiosphaera Seu Calvatia, Bombyx Batryticatus, Mirabilitum crystallina, Fructus Gardeniae, Herba Commelinae, Semen Litchi, Radix Gentianae, Radix Scrophulariae, Semen oryzae sativae, Herba Violae, Indigo Naturalis, Rhizoma Imperatae, Caulis Lonicerae, Sargassum, Radix Trichosanthis, Caulis Trachelospermi, the Rhizoma Anemarrhenae, Herba Schizonepetae, Folium Hibisci Mutabilis decocts with water secondary, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 35 minutes, filter first time decoction liquor, first time decoction liquor is poured in container,

(2) add water medicinal residues after first time filtration 5 times amount, decocts boiling, then use slow fire boiling 20 minutes, filter and to obtain second time decoction liquor;

(3) 6 doses are divided into take twice decoction liquor mixing.