CN106619786A - Medicine for treating mumps, and preparation method of medicine - Google Patents

Medicine for treating mumps, and preparation method of medicine Download PDF

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CN106619786A
CN106619786A CN201611128545.6A CN201611128545A CN106619786A CN 106619786 A CN106619786 A CN 106619786A CN 201611128545 A CN201611128545 A CN 201611128545A CN 106619786 A CN106619786 A CN 106619786A
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张云侠
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
    • A61K36/195—Strobilanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315—Isatis, e.g. Dyer's woad
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/85—Verbenaceae (Verbena family)
    • A61K36/855—Clerodendrum, e.g. glorybower
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a medicine for treating mumps and a preparation method of the medicine. The medicine is mainly prepared from folium hibisci mutabilis, radix et caulis opuntiae dillenii, folium isatidis, herba taraxaci, parslane herb, indigo naturalis, honeysuckle flower, borneol and albolene according to a certain weight ratio. The medicine has the functions of relieving swelling and pain and removing heat to cool blood, and is quick in response and good in curative effect when being used for treating the mumps.

Description

It is a kind of to treat medicine of mumps and preparation method thereof
Technical field
The present invention relates to a kind of treat medicine of mumps and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Mumps abbreviation parotitiss or the stream cheek are respiratory infectious diseases common in Children and teenager, by the parotid gland Scorching virus is caused, and there are prevalence in the four seasons.The apyetouses swelling pain of the parotid gland is prominent symptom, and virus can invade various glands Tissue or the almost all of organ such as nervous system and liver, kidney, the heart, joint.Therefore, meningoencephalitiss, orchitiss, pancreas can often be caused The symptoms such as adenitises, mastitis, oophoritis.Due to current Western medicine cannot effectively treatment mumps, therefore people are to quick There is great demand in the Chinese medicine of effectively treatment mumps, up to now, it has not been found that with regard to the present invention's Relevant report.
The content of the invention
The present inventor have found effectively treatment popular finally according to the checking repeatedly of research and the clinical trial of theory of Chinese medical science The parotitic medicine of property, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of more effective treatment mumps.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention be select Folium Hibisci Mutabiliss, Radix et Caulis Opuntiae Dillenii, Folium Isatidiss, Herba Taraxaci, Herba Portulacae, Indigo Naturaliss, Flos Lonicerae, Flos Chrysanthemi, Radix Isatidis, Radix Trichosanthis, Borneolum Syntheticum, white vaseline are combined, and cause each efficacy of drugs to produce collaboration these drug regimens and make With such that it is able to effectively treatment mumps.Wherein it is because its nature and flavor micro-pungent from Folium Hibisci Mutabiliss, cool, return lung, Liver Channel, There is a Qingfei Liangxue, radiating removing toxic substances, the function of detumescence and apocenosis controls cough due to lung-heat, acute appendicitis, controlling outward carbuncle swells, glue ear, innominate toxic swelling, burn, Scald.It is because that its nature and flavor is bitter from Radix et Caulis Opuntiae Dillenii, trembles with fear, enter the heart, lung, the Jing of stomach three has promoting flow of QI and blood, and the function of heat-clearing and toxic substances removing is controlled Heart peratodynia, mass in the abdomen, dysentery, hemorrhoidal bleeding, cough, laryngalgia, lung abscess, acute mastitis, furuncle, burn, snakebite.It is because from Folium Isatidiss Its nature and flavor is bitter, trembles with fear, and enter liver, the heart, stomach have heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls epidemic febrile disease intenseness of heat excessive thirst, popular sexy Emit, acute infectious hepatitis, bacillary dysentery, acute gastroenteritiss, acute pneumonia, erysipelas, spit blood, epistaxis, jaundice, dysentery, sore throat, mouth Skin ulcer, swollen ulcer drug.Its nature and flavor bitter sweet is because from Herba Taraxaci, is trembled with fear, enter liver, stomach have heat-clearing and toxic substances removing, the work(of diuresis eliminating stagnation Can, acute mastitiss are controlled, lymphadenitises, scrofula, malignant boil carbuncle toxin, acute conjunctivitiss, cold, fever, acute tonsillitiss are acute Bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Its nature and flavor acid is because from Herba Portulacae, is trembled with fear, enter large intestine, liver, spleen Jing, there is heat-clearing and toxic substances removing, dissipates the function of blood detumescence, controls hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, Carbuncle swells dislikes sore, erysipelas, scrofula.Choosing It is because that its nature and flavor is salty with Indigo Naturaliss, trembles with fear, enter liver, lung, stomach have a heat clearing away, removing heat from blood, the function of removing toxic substances, controls epidemic febrile disease intenseness of heat, macule, Spit blood, spit blood, little Jing Epilepsy, sore swells, erysipelas, snake bite and insect sting.It is because that its nature and flavor is sweet from Flos Lonicerae, trembles with fear, enters lung, stomach, There is heat clearing away, the function of removing toxic substances controls warm disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Its nature and flavor is because with Flos Chrysanthemi Sweetness and bitterness, it is cool, enter lung, Liver Channel has dispelling wind, and disappear heat, improving eyesight, the function of removing toxic substances, controls headache, dizziness, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, Toxic swelling.It is because that its nature and flavor is bitter from Radix Isatidis, trembles with fear, enter liver, stomach blood system have heat clearing away, removing toxic substances, the function of removing heat from blood controls influenza, flows Brain, encephalitis b, pneumonia, erysipelas, pyretic toxicity sends out speckle, and coma tells nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, sore rash.Its property is because from Radix Trichosanthis Sweet in the mouth picric acid, it is cool, enter lung, stomach, have and promote the production of body fluid, quench the thirst, pathogenic fire reducing is moisturized, evacuation of pus, the function of detumescence, and it is thirsty to control calentura, quenches one's thirst, Jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula.It is because that its nature and flavor is worked hard from Borneolum Syntheticum, cool, enter the heart, lung meridian there are logical all keys, dissipates strongly fragrant Fire, removing nebula improving eyesight, the function of reducing swelling and alleviating pain controls apoplexy locked mouth, calentura coma ， Jing Epilepsy expectorant fans, deafness with qi stagnation, sore throat, aphtha, in Otitis, carbuncle, hemorrhoid, conjunctivitiss, enterobiasiss.Its great water proofing property is because from white vaseline, is a kind of moisturizing articles for use, It is usually used in preparing medical ointment and skin care ointment.
Specific embodiment
The drug dose of present invention combination is also that inventor summarizes what is drawn through groping in a large number, and the consumption of each packet is following heavy All there is good therapeutic effect in the range of amount：
15-25 gram of Folium Hibisci Mutabiliss, 15-25 gram of Radix et Caulis Opuntiae Dillenii, 15-25 gram of Folium Isatidiss, 15-25 gram of Herba Taraxaci, 8-12 gram of Herba Portulacae, Indigo Naturaliss 8-12 gram, 13-17 gram of Flos Lonicerae, 13-17 gram of Flos Chrysanthemi, 15-25 gram of Radix Isatidis, 8-12 gram of Radix Trichosanthis, 4-5 gram of Borneolum Syntheticum, Bai Fanshi 200-300 gram of woods
Preferably：
20 grams of Folium Hibisci Mutabiliss, 20 grams of Radix et Caulis Opuntiae Dillenii, 20 grams of Folium Isatidiss, 20 grams of Herba Taraxaci, 10 grams of Herba Portulacae, 10 grams of Indigo Naturaliss, Flos Lonicerae 15 Gram, 15 grams of Flos Chrysanthemi, 20 grams of Radix Isatidis, 10 grams of Radix Trichosanthis, 5 grams of Borneolum Syntheticum, 250 grams of white vaseline
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Folium Hibisci Mutabiliss：Residual branch stalk, impurity are removed, with Water spray, is slightly moistened, shredding, be dried；
2nd, Radix et Caulis Opuntiae Dillenii：Fresh Radix et Caulis Opuntiae Dillenii is extracted according to quantity；
3rd, Folium Isatidiss：Impurity and dead leaf are picked, is cleaned；
4th, Herba Taraxaci：Impurity is picked, soil is cleaned；
5th, Herba Portulacae：Net impurity is picked, undesirable root is removed；
6th, Indigo Naturaliss：Impurity is picked, is sieved；
7th, Flos Lonicerae：Pick net impurity；
8th, Flos Chrysanthemi：Pick net leaf stalk, anthocaulus and spare impurity；
9th, Radix Isatidis：Net impurity is picked, is cleaned；
10th, Radix Trichosanthis：Impurity is picked, size block is separate, pulled out with blister about sixty percent thoroughly, moistening to inside and outside humidity is uniform, cuts Piece, dries；Or wash, pull out, shine to extremely dry, it is pounded fritter；
11st, Borneolum Syntheticum：Original is used as medicine；
12nd, white vaseline：Extract according to quantity.
2nd, prepare
1st, by the Folium Hibisci Mutabiliss after processing, Radix et Caulis Opuntiae Dillenii, Folium Isatidiss, Herba Taraxaci, Herba Portulacae, Flos Lonicerae, Flos Chrysanthemi, Radix Isatidis, Radix Trichosanthis Clean up and be placed in open air and dry, smash；
2nd, the spice smashed is dried and Indigo Naturaliss, Borneolum Syntheticum are ground into fine powder by above-mentioned；
3rd, white vaseline mixing and stirring is added to obtain final product the ointment for the treatment of mumps the spice ground as fine powder.
Medicine of the present invention has reducing swelling and alleviating pain, the function of clearing away heat and cooling blood, for treating mumps instant effect, curative effect It is good.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these tests include medicine of the present invention Animal toxicity test and clinical observation on the therapeutic effect test.
The animal toxicity test of [test example 1] medicine of the present invention
West Germany rabbit 10 is taken, rabbit abdominal part hair removing is first exposed skin by male and female dual-purpose, body weight 2.0-2.5kg, then will The ointment for having configured is applied at rabbit abdominal part baring skin, is then twined with gauze and is tied up, daily coating 1 time, continuous coating 5 days, The reaction of observation administration daily, as a result shows that rabbit activity, diet are normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept out-patient totally 47 for medical treatment.
2nd, diagnostic criteria
Have heating, fear of cold, headache, myalgia, pharyngalgia, be off one's feed, the symptom such as Nausea and vomiting, general malaise, parotid gland swelling and pain is bright Aobvious, body temperature is up to more than 39 DEG C.Unilateral or bilateral apyetouses parotid gland swelling and pain or other salivary gland swell and ache after 1～2 day.Eat acidity Distending pain becomes apparent from during food.The visible redness of orifice of parotid duct.Tip Leukocyte Counts are normal or slightly lower, and later stage lymphocyte increases Plus.Premorbid has close contact history in 1～4 week with parotitiss patient.
3rd, Therapeutic Method
（1）First disease sites warm water soaking 15 minutes；
（2）The affected part towel that immersion is finished；
（3）The ointment for preparing is coated in affected part, three times a day, continuous coating 7 days.
4th, efficacy assessment standard
It is effective：Mumps symptom is fully recovered, and recovers normal；
Take a turn for the better：Mumps disease states mitigate, and the state of an illness progressively takes a turn for the better；
It is invalid：Improvement standard person is not reached.
5th, therapeutic outcome（See the table below）：
In above-mentioned treatment, with Drug therapy mumps patient 47 of the present invention, as a result effective 45, obvious effective rate is 95.74%, take a turn for the better 2, improvement rate is 4.26%, and invalid 0, total effective rate is 100%.

Claims (3)

1. a kind of medicine for treating mumps, it is characterised in that：It is made up of the crude drug in following weight range：
15-25 gram of Folium Hibisci Mutabiliss, 15-25 gram of Radix et Caulis Opuntiae Dillenii, 15-25 gram of Folium Isatidiss, 15-25 gram of Herba Taraxaci, 8-12 gram of Herba Portulacae, Indigo Naturaliss 8-12 gram, 13-17 gram of Flos Lonicerae, 13-17 gram of Flos Chrysanthemi, 15-25 gram of Radix Isatidis, 8-12 gram of Radix Trichosanthis, 4-5 gram of Borneolum Syntheticum, Bai Fanshi 200-300 gram of woods.
2. medicine according to claim 1, wherein the consumption of each crude drug is：
20 grams of Folium Hibisci Mutabiliss, 20 grams of Radix et Caulis Opuntiae Dillenii, 20 grams of Folium Isatidiss, 20 grams of Herba Taraxaci, 10 grams of Herba Portulacae, 10 grams of Indigo Naturaliss, Flos Lonicerae 15 Gram, 15 grams of Flos Chrysanthemi, 20 grams of Radix Isatidis, 10 grams of Radix Trichosanthis, 5 grams of Borneolum Syntheticum, 250 grams of white vaseline.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：
（One）Get the raw materials ready
（1）Folium Hibisci Mutabiliss：Residual branch stalk, impurity are removed, with Water spray, is slightly moistened, shredding, be dried；
（2）Radix et Caulis Opuntiae Dillenii：Fresh Radix et Caulis Opuntiae Dillenii is extracted according to quantity；
（3）Folium Isatidiss：Impurity and dead leaf are picked, is cleaned；
（4）Herba Taraxaci：Impurity is picked, soil is cleaned；
（5）Herba Portulacae：Net impurity is picked, undesirable root is removed；
（6）Indigo Naturaliss：Impurity is picked, is sieved；
（7）Flos Lonicerae：Pick net impurity；
（8）Flos Chrysanthemi：Pick net leaf stalk, anthocaulus and spare impurity；
（9）Radix Isatidis：Net impurity is picked, is cleaned；
（10）Radix Trichosanthis：Impurity is picked, size block is separate, pulled out with blister to sixty percent thoroughly, moistening to inside and outside humidity is uniform, cuts Piece, dries；Or wash, pull out, shine to extremely dry, it is pounded fritter；
（11）Borneolum Syntheticum：Original is used as medicine；
（12）White vaseline：Extract according to quantity；
（Two）Prepare
（1）By the Folium Hibisci Mutabiliss after processing, Radix et Caulis Opuntiae Dillenii, Folium Isatidiss, Herba Taraxaci, Herba Portulacae, Flos Lonicerae, Flos Chrysanthemi, Radix Isatidis, Radix Trichosanthis Clean up and be placed in open air and dry, smash；
（2）The spice smashed is dried by above-mentioned and Indigo Naturaliss, Borneolum Syntheticum are ground into fine powder；
（3）White vaseline mixing and stirring is added to obtain final product the ointment for the treatment of mumps the spice ground as fine powder.
CN201611128545.6A 2016-12-09 2016-12-09 Medicine for treating mumps, and preparation method of medicine Withdrawn CN106619786A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638399A (en) * 2013-12-10 2014-03-19 张朝兰 Medicine for treating infantile mumps and preparation method of medicine
CN105617178A (en) * 2016-01-20 2016-06-01 赵世明 Traditional Chinese medicine composition for treating epidemic parotitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103638399A (en) * 2013-12-10 2014-03-19 张朝兰 Medicine for treating infantile mumps and preparation method of medicine
CN105617178A (en) * 2016-01-20 2016-06-01 赵世明 Traditional Chinese medicine composition for treating epidemic parotitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李鑫辉 等: "《常见传染病中医证治荟萃》", 30 September 2016, 中国中医药出版社 *

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