CN105362993A - Tincture for treating ichthyophthiriasis of parrotfish and preparation method of tincture for treating ichthyophthiriasis of parrotfish - Google Patents

Tincture for treating ichthyophthiriasis of parrotfish and preparation method of tincture for treating ichthyophthiriasis of parrotfish Download PDF

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CN105362993A
CN105362993A CN201510861535.2A CN201510861535A CN105362993A CN 105362993 A CN105362993 A CN 105362993A CN 201510861535 A CN201510861535 A CN 201510861535A CN 105362993 A CN105362993 A CN 105362993A
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parts
herba
tincture
rhizoma
ichthyophthiriasis
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CN201510861535.2A
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王芬
李洪
孙明
王亮
宋辉
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Qingdao Haizhiyuan Intelligent Technology Co Ltd
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Qingdao Haizhiyuan Intelligent Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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Abstract

The invention belongs to the technical field of aquaculture and relates to a tincture for treating ichthyophthiriasis of parrotfish and a preparation method of the tincture for treating the ichthyophthiriasis of the parrotfish. The tincture is prepared from, by weight, 36-42 parts of acorus calamus, 30-35 parts of sweet potato, 28-35 parts of fructus gleditsiae, 28-34 parts of honeysuckle, 28-34 parts of peach leaves, 27-34 parts of radix sanguisorbae, 25-33 parts of lavandula angustifolia, 24-32 parts of herba scutellariae barbatae, 24-30 parts of fructus schisandrae chinensis, 21-27 parts of herba artemisiae capillaris, 21-27 parts of herba patriniae, 20-26 parts of root of juncus effusus, 19-27 parts of cheilosoria chusana, 19-25 parts of acacia catechu, 14-21 parts of garlic, 12-20 parts of herba hedyotis diffusae and the like. The medicine is effective in treatment of the ichthyophthiriasis of the parrotfish.

Description

Tincture for the treatment of parrot fish ichthyophthiriasis and preparation method thereof
Technical field
The invention belongs to technical field of aquaculture, particularly relate to a kind of tincture for the treatment of parrot fish ichthyophthiriasis; The invention still further relates to a kind of preparation method of tincture of above-mentioned treatment parrot fish ichthyophthiriasis.
Background technology
Along with the growth in the living standard of people, material life is enriched greatly, and the requirement that people live to amusement and recreation is more and more obvious, and staying at home or supporting pet fish beautiful in colour a bit in garden is best selection, takes up room hardly because raise pet fish; Economic cost can be determined according to people; Condition is relatively simple, has water.Cultivation of ornamental fish not only can cultivate the body and the mind, and cultivate one's taste, the anion discharged in water and steam also can filter and wet air, build good living environment to people.
Parrot fish (formal name used at school: Amphilophus) or title parrot fish, parrot fish, formal name used at school Lip river god's neck fin fish, labrid genus class, being commonly called as parrot fish, parrot fish, red wedge Channa argus etc., is the tropic fishes lived in coral reef.Parrot fish color is equally gorgeous well-known with Psittacula alexandri fasciata, and body colour differs, and middle male and female of the same race are widely different, and between adult fish and germling fish, difference is also very large.Because it is beautiful in colour, nozzle type exactly likes Psittacula alexandri fasciata nozzle type and gains the name.Parrot fish is dark liking by pet fish fan because of its gorgeous body colour.
Ichthyophthiriasis is a kind of modal Fish parasitic disease, is mainly in the Cyprinidae and the tropical fish comparatively easy infection of Family Cichlidae in season that water temperature at the beginning of last month of spring in autumn is lower.Ichthyophthiriasis is also ichthyophthiriasis, and little melonworm polypide is spherical in shape, and whole body has draped over one's shoulders cilium, and diameter is about 0.8mm, is macroscopic small particles.When water temperature 18-23 DEG C, little melonworm often colonizes in subcutaneous, tail fin and the gill portion of fish, sucks the nutrition of Fish tissue, and stimulates fish body to secrete a large amount of mucus, therefore forms white pus bubble one by one at fish body surface, spreads all over fish whole body.Tropical fish suffer from this sick time, show and fin first occur white point, fish seem dull mind, float on the water surface, seldom movable, or pasture and water of being everlasting, sandstone side body rapidly travelling rubbing itch.Time serious, cause fish body the whole body gather white point, stopping is ingested, human body is become thin, dyspnea until death, the course of disease is generally about 5-10 days.If run under temperature shock or fish resist hypodynamic situation, parrot fish will large-scale outbreak ichthyophthiriasis.Parrot fish ichthyophthiriasis not only affects the sight of parrot fish, but also can cause the death of parrot fish and then bring serious economic loss.At present, the means of usual employing for the treatment of ichthyophthiriasis change water salting or with Mercury protonitrate. or use malachite green oxalate dipping, is its limited efficiency and cure rate is low by the shortcoming of Sal immersion, can not make parrot fish speedy recovery to health, the healing cycle is long, cannot effectively deal with problems; And with Mercury protonitrate. or too large by malachite green oxalate toxicity, not only pollute the environment, and it is large to the toxic and side effects of parrot fish, in addition, Mercury protonitrate. or also have very large toxicity to Corallium Japonicum Kishinouye and invertebrates with malachite green oxalate, directly can not put in poison in Corallium Japonicum Kishinouye cylinder, need to carry out in independent quarantine cylinder, operate comparatively loaded down with trivial details.
Summary of the invention
An object of the present invention is to provide a kind of tincture for the treatment of parrot fish ichthyophthiriasis, and its raw material components is green pure natural material, effectively can treat the ichthyophthiriasis of parrot fish.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions, a kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 36-42 part, Rhizoma Dioscoreae esculentae 30-35 part, Fructus Gleditsia 28-35 part, Flos Lonicerae 28-34 part, Folium Persicae 28-34 part, Radix Sanguisorbae 27-34 part, lavandula angustifolia 25-33 part, Herba Scutellariae Barbatae 24-32 part, Fructus Schisandrae Chinensis 24-30 part, Artemisia anethoicles Mattf 21-27 part, Herba Patriniae 21-27 part, Juncus effusus L. Var.Decipiens Buchen. 20-26 part, Herba Cheilanthes chusane 19-27 part, catechu 19-25 part, attached column flower 18-25 part, smartweed 16-25 part, Radix Stephaniae Cepharanthae 15-23 part, Rhizoma Atractylodis Macrocephalae 15-21 part, Herba Violae 15-21 part, Bulbus Allii 14-21 part, Herba Hedyotidis Diffusae 12-20 part, Herba Portulacae 12-19 part, Rhizoma Zingiberis Recens 12-17 part, bamboo salt 11-17 part, Mel 9-17 part, hyaluronic acid 3-6 part, mass concentration is ethanol 23-32 part of 75%.
Preferably, the tincture of described treatment parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 39 parts, Rhizoma Dioscoreae esculentae 33 parts, 32 parts, Fructus Gleditsia, Flos Lonicerae 30 parts, Folium Persicae 30 parts, Radix Sanguisorbae 31 parts, lavandula angustifolia 30 parts, Herba Scutellariae Barbatae 28 parts, Fructus Schisandrae Chinensis 27 parts, Artemisia anethoicles Mattf 24 parts, Herba Patriniae 24 parts, Juncus effusus L. Var.Decipiens Buchen. 23 parts, Herba Cheilanthes chusane 23 parts, 22 parts, catechu, attached column spends 22 parts, smartweed 20 parts, Radix Stephaniae Cepharanthae 19 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Herba Violae 18 parts, 18 parts, Bulbus Allii, Herba Hedyotidis Diffusae 16 parts, Herba Portulacae 15 parts, 14 parts, Rhizoma Zingiberis Recens, bamboo salt 15 parts, Mel 12 parts, hyaluronic acid 4 parts, mass concentration is the ethanol 27 parts of 75%.
Preferably, the tincture of described treatment parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 40 parts, Rhizoma Dioscoreae esculentae 33 parts, 31 parts, Fructus Gleditsia, Flos Lonicerae 31 parts, Folium Persicae 32 parts, Radix Sanguisorbae 30 parts, lavandula angustifolia 28 parts, Herba Scutellariae Barbatae 28 parts, Fructus Schisandrae Chinensis 27 parts, Artemisia anethoicles Mattf 25 parts, Herba Patriniae 25 parts, Juncus effusus L. Var.Decipiens Buchen. 22 parts, Herba Cheilanthes chusane 23 parts, 22 parts, catechu, attached column spends 21 parts, smartweed 21 parts, Radix Stephaniae Cepharanthae 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Herba Violae 17 parts, 17 parts, Bulbus Allii, Herba Hedyotidis Diffusae 16 parts, Herba Portulacae 16 parts, 15 parts, Rhizoma Zingiberis Recens, bamboo salt 14 parts, Mel 13 parts, hyaluronic acid 5 parts, mass concentration is the ethanol 28 parts of 75%.
Each component effect of the present invention is resolved as follows:
Rhizoma Acori Graminei can be prevented epidemic and be got rid of evils, and is fabulous " environment friendly agricultural ", can effectively treats the insect pests such as planthopper, rice leafhopper, rice green caterpillar, aphid, red spider.Rhizoma Dioscoreae esculentae nature and flavor are sweet flat, nontoxic, can tonifying the spleen and stomach, nourishing the heart to keep a sound mind, physical strength profiting, promoting lactation, except place stasis of blood dysentery, the dehydroepiandrosterone that Rhizoma Dioscoreae esculentae is exclusive, can prevent colon cancer and mammary gland, Rhizoma Dioscoreae esculentae can improve the immunocompetence of body.Fructus Gleditsia is containing triterpenoid saponin (gledinin, gleditschiasaponin), tannin, ceryl alcohol, nonacosane, stigmasterol, sitosterol etc., the function of have eliminating the phlegm, having one's ideas straightened out, saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, there are antiinflammatory, antiulcer, disease-resistant change effect, also have anticancer and improve the effects such as acquired immune deficiency syndrome (AIDS) immunity.The sweet cold fragrance of Flos Lonicerae property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil, Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, send out speckle, pyretic toxicity carbuncle sore, the diseases such as laryngopharynx swelling and pain, equal Be very effective, Flos Lonicerae contains chlorogenic acid, the pharmacological components such as luteolin glycosides, to Hemolytic streptococcus, the various pathogens such as staphylococcus aureus and upper respiratory tract infection Causative virus etc. have stronger restraint, in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, respiratory tract infection can be used for the treatment of with other medicines compatibility, bacillary dysentery, acute urinary, hypertension etc. more than 40 plant disease.Folium Persicae bitter in the mouth, property is put down, and is applicable to malaria, carbuncle furuncle, hemorrhoid, eczema, the treatment of the diseases such as trichomonas vaginitis.Radix Sanguisorbae cold nature, bitter in the mouth, Radix Sanguisorbae has hemostasis removing heat from blood, heat-clearing and toxic substances removing, astringing to arrest diarrhea and suppresses the effect of multiple pathogenic microorganism and tumor, haematemesis, dysentery can be treated, burn wound, eczema, upper gastrointestinal hemorrhage, Peptic Ulcers massive hemorrhage, have blood in stool, metrorrhagia, the disease such as Tuberculous pus infections and chronic osteomyelitis.Linalool in lavandula angustifolia can suppress the growth of 17 kinds of antibacterials (comprising gram positive bacteria and gram-negative bacteria), 10 kinds of funguses, and lavandula angustifolia has neuroprotective.Herba Scutellariae Barbatae has removing pathogenic heat from blood and toxic substance from the body, eliminating stasis to stop pain, effect of detumescence and clearing away heat-damp and promoting diuresis.Fructus Schisandrae Chinensis is astringed the lung, nourishing kidney, promotes the production of body fluid, and receive antiperspirant, arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.The raw pathogenic heat gas of Artemisia anethoicles Mattf main air, Herba Artemisiae Scopariae has remarkable choleretic effect, and have antipyretic, protect the liver, the effect such as antitumor and blood pressure lowering.Herba Patriniae heat-clearing and toxic substances removing, removing blood stasis and expelling pus, the antiinflammatory of energy sterilization and disinsection, can be used for appendicitis, dysentery, ichthyophthiriasis, hepatitis, eye conjunctivitis, postnatal blood stasis stomachache, carbuncle furuncle etc.Juncus effusus L. Var.Decipiens Buchen. can bactericidal.Herba Cheilanthes chusane controls dysentery, urine pain, and foot is soft unable, fever with pantalgia, laryngalgia, venom, carbuncle furuncle and phyma scrofula.Catechu is used for falling flutters the pain of injury, traumatic hemorrhage, hematemesis and epistaxis, and skin infection is not held back, eczema, eczema, cough due to lung-heat.Attached column flower energy heat-clearing and toxic substances removing; Dampness removing is antipruritic; Reducing swelling and alleviating pain, main dysentery; Skin infection; Eczema; Skin pruritus; Caterpillar is stabbed; Traumatic injury.Smartweed expelling wind and removing dampness; Invigorate blood circulation; Preventing the attack (or recurrence) of malaria, main air pain of dampness syndrome; Dysentery; Diarrhoea; Vomit and diarrhoea and have a cramp; Edema; Foot gas; Carbuncle skin ulcer furuncle furuncle; Snake bite and insect sting; Infantile malnutrition hernia; Traumatic injury; Malaria.Radix Stephaniae Cepharanthae energy wind-expelling pain-stopping; Cooling blood for hemostasis, main laryngopharynx swelling and pain; Pyretic toxicity carbuncle; Rheumatic arthralgia; Stomachache; Dysentery; Spit blood; Epistaxis; Traumatic hemorrhage.The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, and for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Herba Violae removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Bulbus Allii acrid in the mouth warm in nature, warming middle-JIAO stomach invigorating, helps digestion and regulates the flow of vital energy, removing toxic substances parasite killing, reducing swelling and alleviating pain, antidiarrheal dysentery relieving, control lung, anthelmintic, also have warming the spleen warming the stomach in addition, control swollen ulcer drug, white bald tinea skin ulcer, dysentery is had loose bowels, pulmonary tuberculosis pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, edema distension.Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.The blind white clouds of Herba Portulacae argument, sharp defecation, cold removing heat, kills parasites, quenches the thirst, broken crux carbuncle skin ulcer, and vinegar dregs for many years, when disliking thing under profit, removes tapeworm.Rhizoma Zingiberis Recens has strong bactericidal action to Bacillus typhi and vibrio cholera, inhibitory action is had to trichophyton, zingiberol contained in Rhizoma Zingiberis Recens and gingerol have to be killed Mollusca and kills bilharzial effect, can be used for treating schistosomicide, and there is obvious analgesic activity, Rhizoma Zingiberis Recens warms up, can blood circulation promoting unimpeded.Bamboo salt has antibacterial, antiinflammatory, toxopexic effect.Mel sweet in the mouth, property are flat, return spleen, lung, the heart, stomach, large intestine channel, have the effect of nourshing Yin and drynsessmoistening prescription, tonify deficiency lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Hyaluronic acid can improve skin-nourishing metabolism, and make that skin is tender, smooth, wrinkle removing, increase elasticity, prevent aging, be again good Percutaneous absorption enhancer while moisturizing.Select mass concentration be 75% ethanol can extract effective ingredient in medicine preferably, and the activity of each effective ingredient can be kept preferably.
Another object of the present invention is to provide a kind of preparation method of tincture of above-mentioned treatment parrot fish ichthyophthiriasis, and the preparation method of the tincture of this treatment parrot fish ichthyophthiriasis comprises the following steps:
(1) take Rhizoma Acori Graminei, Rhizoma Dioscoreae esculentae, Fructus Gleditsia, Flos Lonicerae, Folium Persicae, Radix Sanguisorbae, lavandula angustifolia, Bulbus Allii, Rhizoma Zingiberis Recens according to proportioning, gross weight is designated as 1 part, adds 8 parts of purified water, and 40-50 DEG C is soaked 1h, obtain soak;
(2) boil 2h after the soak that step (1) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 4 parts in medical material, continue to boil 1.5h after being heated to boiling, merge twice fried liquid and be extracting solution;
(3) take the Rhizoma Atractylodis Macrocephalae, Herba Violae, Herba Hedyotidis Diffusae and Herba Portulacae respectively according to proportioning, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(4) Herba Scutellariae Barbatae, Fructus Schisandrae Chinensis, Artemisia anethoicles Mattf, Herba Patriniae, Juncus effusus L. Var.Decipiens Buchen., Herba Cheilanthes chusane, catechu, attached column flower, smartweed and Radix Stephaniae Cepharanthae is taken according to proportioning, and mix, the Pulvis concha Mactrae that weight is 1/2nd of mixed powder gross weight is added in mixed powder, 120 ~ 160 DEG C of parches of advancing after adding Pulvis concha Mactrae, after parch completes, remove Pulvis concha Mactrae, then put into pulverizer and pulverize and cross 100 mesh sieves, obtain comminuted powder;
(5) take according to proportioning the ethanol that mass concentration is 75%, the grounds travel that the extracting solution obtain step (2) and step (3) obtain, the comminuted powder of step (4) gained and load weighted ethanol are positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, and separator temperature is 70 DEG C, extract 2 hours, be extracted liquid;
(6) take bamboo salt, Mel and hyaluronic acid respectively according to proportioning, and mix homogeneously with the extract of step (5) gained, obtain object.
Usage and dosage: the disease sites being applied in disease fish every day for 1-2 time.
Storage: lucifuge, shady and cool dry place storage.
In preparation method, by Rhizoma Acori Graminei, Rhizoma Dioscoreae esculentae, Fructus Gleditsia, Flos Lonicerae, Folium Persicae, Radix Sanguisorbae, lavandula angustifolia, Bulbus Allii, Rhizoma Zingiberis Recens crude drug purified water soaking a period of time, medical material deliquescing, cell expansion, effective ingredient is easily fried, and medical material contains starch, protein, after soaking, prevent when decocting, the starch gelatinization on medical material surface, protein coagulating, the capillary channel on blocking medical material surface, make the moisture when decocting enter not go, effective ingredient is not easily fried, affects curative effect of medication; Decoct after soaking and can change the irritation effect of medicine, relatively mildly act on parrot fish, promote that parrot fish is to the absorption of medicine; The object of the Rhizoma Atractylodis Macrocephalae, Herba Violae, Herba Hedyotidis Diffusae and Herba Portulacae being ground is the starch made in medical material, protein is separated out more fully at subsequent step; Supercritical extraction, immersion, concentration step retain the effective ingredient of each component in the present invention to greatest extent.Pulvis concha Mactrae is utilized to carry out parch to Herba Scutellariae Barbatae, Fructus Schisandrae Chinensis, Artemisia anethoicles Mattf, Herba Patriniae, Juncus effusus L. Var.Decipiens Buchen., Herba Cheilanthes chusane, catechu, attached column flower, smartweed and Radix Stephaniae Cepharanthae, reduce the cool property of raw material, correct bad smell, be conducive to the absorption of fish, and Pulvis concha Mactrae parch can strengthen the effect of the bactericidal antiphlogistic of raw material.Select mass concentration be 75% ethanol can extract effective ingredient in medicine preferably, and the activity of each effective ingredient can be kept preferably.
The tincture for the treatment of parrot fish ichthyophthiriasis of the present invention is the etiopathogenesis according to ichthyophthiriasis, the suitable component of selection, and is organically combined, and has significant cooperative synergism effect, plays the function of each component to greatest extent.The component of the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention is environmental protection raw material, nontoxic to environment, not containing chemical drugs or antibiotic, and tincture of the present invention is good to the curative effect of parrot fish ichthyophthiriasis, cure rate is high, make the survival rate of ill parrot fish to more than 90%, after medication 1-2 days, parrot fish white point with it can all disappear.In addition, the present invention uses safer, little to parrot fish damage, relatively mildly can act on parrot fish; after using the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention, parrot fish Health restoration is fast, medication 2-4 days; parrot fish can recover normal activity, and idle fund is strong and vigorous, ingests completely normal.
Compared with prior art, the invention has the beneficial effects as follows:
(1) in each component of the present invention, Rhizoma Acori Graminei is monarch drug, can prevent epidemic and get rid of evils, and is fabulous " environment friendly agricultural ", can effectively treats the insect pests such as planthopper, rice leafhopper, rice green caterpillar, aphid, red spider.
Rhizoma Dioscoreae esculentae, Fructus Gleditsia, Flos Lonicerae, Folium Persicae, Radix Sanguisorbae and lavandula angustifolia are ministerial drug.Rhizoma Dioscoreae esculentae nature and flavor are sweet flat, nontoxic, can tonifying the spleen and stomach, nourishing the heart to keep a sound mind, physical strength profiting, promoting lactation, except place stasis of blood dysentery, the dehydroepiandrosterone that Rhizoma Dioscoreae esculentae is exclusive, can prevent colon cancer and mammary gland, Rhizoma Dioscoreae esculentae can improve the immunocompetence of body.Fructus Gleditsia is containing triterpenoid saponin (gledinin, gleditschiasaponin), tannin, ceryl alcohol, nonacosane, stigmasterol, sitosterol etc., the function of have eliminating the phlegm, having one's ideas straightened out, saponin element contained in Fructus Gleditsia is triterpene class and oligosaccharide, there are antiinflammatory, antiulcer, disease-resistant change effect, also have anticancer and improve the effects such as acquired immune deficiency syndrome (AIDS) immunity.The sweet cold fragrance of Flos Lonicerae property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil, Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, send out speckle, pyretic toxicity carbuncle sore, the diseases such as laryngopharynx swelling and pain, equal Be very effective, Flos Lonicerae contains chlorogenic acid, the pharmacological components such as luteolin glycosides, to Hemolytic streptococcus, the various pathogens such as staphylococcus aureus and upper respiratory tract infection Causative virus etc. have stronger restraint, in addition also can enhancing immunity, antiearly pregnancy, hepatoprotective, antitumor, antiinflammatory, antipyretic, hemostasis (blood coagulation), suppress intestinal absorption cholesterol etc., its clinical application widely, respiratory tract infection can be used for the treatment of with other medicines compatibility, bacillary dysentery, acute urinary, hypertension etc. more than 40 plant disease.Folium Persicae bitter in the mouth, property is put down, and is applicable to malaria, carbuncle furuncle, hemorrhoid, eczema, the treatment of the diseases such as trichomonas vaginitis.Radix Sanguisorbae cold nature, bitter in the mouth, Radix Sanguisorbae has hemostasis removing heat from blood, heat-clearing and toxic substances removing, astringing to arrest diarrhea and suppresses the effect of multiple pathogenic microorganism and tumor, haematemesis, dysentery can be treated, burn wound, eczema, upper gastrointestinal hemorrhage, Peptic Ulcers massive hemorrhage, have blood in stool, metrorrhagia, the disease such as Tuberculous pus infections and chronic osteomyelitis.Linalool in lavandula angustifolia can suppress the growth of 17 kinds of antibacterials (comprising gram positive bacteria and gram-negative bacteria), 10 kinds of funguses, and lavandula angustifolia has neuroprotective.
Herba Scutellariae Barbatae has removing pathogenic heat from blood and toxic substance from the body, eliminating stasis to stop pain, effect of detumescence and clearing away heat-damp and promoting diuresis.Fructus Schisandrae Chinensis is astringed the lung, nourishing kidney, promotes the production of body fluid, and receive antiperspirant, arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery.The raw pathogenic heat gas of Artemisia anethoicles Mattf main air, Herba Artemisiae Scopariae has remarkable choleretic effect, and have antipyretic, protect the liver, the effect such as antitumor and blood pressure lowering.Herba Patriniae heat-clearing and toxic substances removing, removing blood stasis and expelling pus, the antiinflammatory of energy sterilization and disinsection, can be used for appendicitis, dysentery, ichthyophthiriasis, hepatitis, eye conjunctivitis, postnatal blood stasis stomachache, carbuncle furuncle etc.Juncus effusus L. Var.Decipiens Buchen. can bactericidal.Herba Cheilanthes chusane controls dysentery, urine pain, and foot is soft unable, fever with pantalgia, laryngalgia, venom, carbuncle furuncle and phyma scrofula.Catechu is used for falling flutters the pain of injury, traumatic hemorrhage, hematemesis and epistaxis, and skin infection is not held back, eczema, eczema, cough due to lung-heat.Attached column flower energy heat-clearing and toxic substances removing; Dampness removing is antipruritic; Reducing swelling and alleviating pain, main dysentery; Skin infection; Eczema; Skin pruritus; Caterpillar is stabbed; Traumatic injury.Smartweed expelling wind and removing dampness; Invigorate blood circulation; Preventing the attack (or recurrence) of malaria, main air pain of dampness syndrome; Dysentery; Diarrhoea; Vomit and diarrhoea and have a cramp; Edema; Foot gas; Carbuncle skin ulcer furuncle furuncle; Snake bite and insect sting; Infantile malnutrition hernia; Traumatic injury; Malaria.Mel sweet in the mouth, property are flat, return spleen, lung, the heart, stomach, large intestine channel, have the effect of nourshing Yin and drynsessmoistening prescription, tonify deficiency lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.Hyaluronic acid can improve skin-nourishing metabolism, and make that skin is tender, smooth, wrinkle removing, increase elasticity, prevent aging, be again good Percutaneous absorption enhancer while moisturizing.Select mass concentration be 75% ethanol can extract effective ingredient in medicine preferably, and the activity of each effective ingredient can be kept preferably.Herba Scutellariae Barbatae, Fructus Schisandrae Chinensis, Artemisia anethoicles Mattf, Herba Patriniae, Juncus effusus L. Var.Decipiens Buchen., Herba Cheilanthes chusane, catechu, attached column flower, smartweed, Mel, hyaluronic acid and mass concentration be 75% ethanol be adjuvant drug.
Radix Stephaniae Cepharanthae energy wind-expelling pain-stopping; Cooling blood for hemostasis, main laryngopharynx swelling and pain; Pyretic toxicity carbuncle; Rheumatic arthralgia; Stomachache; Dysentery; Spit blood; Epistaxis; Traumatic hemorrhage.The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, and for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Herba Violae removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.Bulbus Allii acrid in the mouth warm in nature, warming middle-JIAO stomach invigorating, helps digestion and regulates the flow of vital energy, removing toxic substances parasite killing, reducing swelling and alleviating pain, antidiarrheal dysentery relieving, control lung, anthelmintic, also have warming the spleen warming the stomach in addition, control swollen ulcer drug, white bald tinea skin ulcer, dysentery is had loose bowels, pulmonary tuberculosis pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, edema distension.Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.The blind white clouds of Herba Portulacae argument, sharp defecation, cold removing heat, kills parasites, quenches the thirst, broken crux carbuncle skin ulcer, and vinegar dregs for many years, when disliking thing under profit, removes tapeworm.Rhizoma Zingiberis Recens has strong bactericidal action to Bacillus typhi and vibrio cholera, inhibitory action is had to trichophyton, zingiberol contained in Rhizoma Zingiberis Recens and gingerol have to be killed Mollusca and kills bilharzial effect, can be used for treating schistosomicide, and there is obvious analgesic activity, Rhizoma Zingiberis Recens warms up, can blood circulation promoting unimpeded.Bamboo salt has antibacterial, antiinflammatory, toxopexic effect.Radix Stephaniae Cepharanthae, the Rhizoma Atractylodis Macrocephalae, Herba Violae, Bulbus Allii, Herba Hedyotidis Diffusae, Herba Portulacae, Rhizoma Zingiberis Recens and bamboo salt are for making medicine.
(2) in preparation method, by Rhizoma Acori Graminei, Rhizoma Dioscoreae esculentae, Fructus Gleditsia, Flos Lonicerae, Folium Persicae, Radix Sanguisorbae, lavandula angustifolia, Bulbus Allii, Rhizoma Zingiberis Recens crude drug purified water soaking a period of time, medical material deliquescing, cell expansion, effective ingredient is easily fried, and medical material contains starch, protein, after soaking, prevent when decocting, the starch gelatinization on medical material surface, protein coagulating, the capillary channel on blocking medical material surface, make the moisture when decocting enter not go, effective ingredient is not easily fried, affects curative effect of medication; Decoct after soaking and can change the irritation effect of medicine, relatively mildly act on parrot fish, promote that parrot fish is to the absorption of medicine; The object of the Rhizoma Atractylodis Macrocephalae, Herba Violae, Herba Hedyotidis Diffusae and Herba Portulacae being ground is the starch made in medical material, protein is separated out more fully at subsequent step; Supercritical extraction, immersion, concentration step retain the effective ingredient of each component in the present invention to greatest extent.Pulvis concha Mactrae is utilized to carry out parch to Herba Scutellariae Barbatae, Fructus Schisandrae Chinensis, Artemisia anethoicles Mattf, Herba Patriniae, Juncus effusus L. Var.Decipiens Buchen., Herba Cheilanthes chusane, catechu, attached column flower, smartweed and Radix Stephaniae Cepharanthae, reduce the cool property of raw material, correct bad smell, be conducive to the absorption of fish, and Pulvis concha Mactrae parch can strengthen the effect of the bactericidal antiphlogistic of raw material.Select mass concentration be 75% ethanol can extract effective ingredient in medicine preferably, and the activity of each effective ingredient can be kept preferably.
(3) tincture for the treatment of parrot fish ichthyophthiriasis of the present invention, is the etiopathogenesis according to ichthyophthiriasis, the suitable component of selection, and is organically combined, and has significant cooperative synergism effect, plays the function of each component to greatest extent.The component of the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention is environmental protection raw material, nontoxic to environment, not containing chemical drugs or antibiotic, and tincture of the present invention is good to the therapeutic effect of parrot fish ichthyophthiriasis, cure rate is high, make the survival rate of ill parrot fish to more than 90%, after medication 1-2 days, parrot fish white point with it can all disappear.In addition, the present invention uses safer, little to parrot fish damage, relatively mildly can act on parrot fish; after using the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention, parrot fish Health restoration is fast, medication 2-4 days; parrot fish can recover normal activity, and idle fund is strong and vigorous, ingests completely normal.
Detailed description of the invention
Following embodiment is convenient to understand the present invention better, but does not limit the present invention.Experimental technique in following embodiment, if no special instructions, is conventional method.
Embodiment 1
A kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 36 parts, Rhizoma Dioscoreae esculentae 32 parts, 30 parts, Fructus Gleditsia, Flos Lonicerae 30 parts, Folium Persicae 28 parts, Radix Sanguisorbae 27 parts, lavandula angustifolia 25 parts, Herba Scutellariae Barbatae 24 parts, Fructus Schisandrae Chinensis 24 parts, Artemisia anethoicles Mattf 21 parts, Herba Patriniae 21 parts, Juncus effusus L. Var.Decipiens Buchen. 22 parts, Herba Cheilanthes chusane 20 parts, 19 parts, catechu, attached column spends 18 parts, smartweed 16 parts, Radix Stephaniae Cepharanthae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Herba Violae 15 parts, 14 parts, Bulbus Allii, Herba Hedyotidis Diffusae 12 parts, Herba Portulacae 12 parts, 12 parts, Rhizoma Zingiberis Recens, bamboo salt 11 parts, Mel 10 parts, hyaluronic acid 3 parts, mass concentration is the ethanol 23 parts of 75%.
The preparation method of the tincture of above-mentioned treatment parrot fish ichthyophthiriasis comprises the following steps:
(1) take Rhizoma Acori Graminei, Rhizoma Dioscoreae esculentae, Fructus Gleditsia, Flos Lonicerae, Folium Persicae, Radix Sanguisorbae, lavandula angustifolia, Bulbus Allii, Rhizoma Zingiberis Recens according to proportioning, gross weight is designated as 1 part, adds 8 parts of purified water, and 40-50 DEG C is soaked 1h, obtain soak;
(2) boil 2h after the soak that step (1) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 4 parts in medical material, continue to boil 1.5h after being heated to boiling, merge twice fried liquid and be extracting solution;
(3) take the Rhizoma Atractylodis Macrocephalae, Herba Violae, Herba Hedyotidis Diffusae and Herba Portulacae respectively according to proportioning, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(4) Herba Scutellariae Barbatae, Fructus Schisandrae Chinensis, Artemisia anethoicles Mattf, Herba Patriniae, Juncus effusus L. Var.Decipiens Buchen., Herba Cheilanthes chusane, catechu, attached column flower, smartweed and Radix Stephaniae Cepharanthae is taken according to proportioning, and mix, the Pulvis concha Mactrae that weight is 1/2nd of mixed powder gross weight is added in mixed powder, 120 ~ 160 DEG C of parches of advancing after adding Pulvis concha Mactrae, after parch completes, remove Pulvis concha Mactrae, then put into pulverizer and pulverize and cross 100 mesh sieves, obtain comminuted powder;
(5) take according to proportioning the ethanol that mass concentration is 75%, the grounds travel that the extracting solution obtain step (2) and step (3) obtain, the comminuted powder of step (4) gained and load weighted ethanol are positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, and separator temperature is 70 DEG C, extract 2 hours, be extracted liquid;
(6) take bamboo salt, Mel and hyaluronic acid respectively according to proportioning, and mix homogeneously with the extract of step (5) gained, obtain object.
Embodiment 2
A kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 38 parts, Rhizoma Dioscoreae esculentae 30 parts, 28 parts, Fructus Gleditsia, Flos Lonicerae 28 parts, Folium Persicae 27 parts, Radix Sanguisorbae 27 parts, lavandula angustifolia 27 parts, Herba Scutellariae Barbatae 25 parts, Fructus Schisandrae Chinensis 26 parts, Artemisia anethoicles Mattf 22 parts, Herba Patriniae 23 parts, Juncus effusus L. Var.Decipiens Buchen. 20 parts, Herba Cheilanthes chusane 19 parts, 20 parts, catechu, attached column spends 18 parts, smartweed 16 parts, Radix Stephaniae Cepharanthae 15 parts, the Rhizoma Atractylodis Macrocephalae 16 parts, Herba Violae 16 parts, 14 parts, Bulbus Allii, Herba Hedyotidis Diffusae 14 parts, Herba Portulacae 12 parts, 12 parts, Rhizoma Zingiberis Recens, bamboo salt 12 parts, Mel 9 parts, hyaluronic acid 4 parts, mass concentration is the ethanol 25 parts of 75%.
The preparation method of the tincture of the treatment parrot fish ichthyophthiriasis of the present embodiment is with embodiment 1.
Embodiment 3
A kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 42 parts, Rhizoma Dioscoreae esculentae 35 parts, 35 parts, Fructus Gleditsia, Flos Lonicerae 33 parts, Folium Persicae 34 parts, Radix Sanguisorbae 33 parts, lavandula angustifolia 33 parts, Herba Scutellariae Barbatae 32 parts, Fructus Schisandrae Chinensis 30 parts, Artemisia anethoicles Mattf 27 parts, Herba Patriniae 27 parts, Juncus effusus L. Var.Decipiens Buchen. 26 parts, Herba Cheilanthes chusane 26 parts, 25 parts, catechu, attached column spends 25 parts, smartweed 24 parts, Radix Stephaniae Cepharanthae 23 parts, the Rhizoma Atractylodis Macrocephalae 21 parts, Herba Violae 21 parts, 20 parts, Bulbus Allii, Herba Hedyotidis Diffusae 20 parts, Herba Portulacae 19 parts, 17 parts, Rhizoma Zingiberis Recens, bamboo salt 17 parts, Mel 16 parts, hyaluronic acid 6 parts, mass concentration is the ethanol 32 parts of 75%.
The preparation method of the tincture of the treatment parrot fish ichthyophthiriasis of the present embodiment is with embodiment 1.
Embodiment 4
A kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 40 parts, Rhizoma Dioscoreae esculentae 34 parts, 34 parts, Fructus Gleditsia, Flos Lonicerae 34 parts, Folium Persicae 32 parts, Radix Sanguisorbae 34 parts, lavandula angustifolia 32 parts, Herba Scutellariae Barbatae 30 parts, Fructus Schisandrae Chinensis 30 parts, Artemisia anethoicles Mattf 27 parts, Herba Patriniae 26 parts, Juncus effusus L. Var.Decipiens Buchen. 26 parts, Herba Cheilanthes chusane 27 parts, 25 parts, catechu, attached column spends 24 parts, smartweed 25 parts, Radix Stephaniae Cepharanthae 22 parts, the Rhizoma Atractylodis Macrocephalae 21 parts, Herba Violae 21 parts, 21 parts, Bulbus Allii, Herba Hedyotidis Diffusae 20 parts, Herba Portulacae 18 parts, 16 parts, Rhizoma Zingiberis Recens, bamboo salt 16 parts, Mel 17 parts, hyaluronic acid 6 parts, mass concentration is the ethanol 30 parts of 75%.
The preparation method of the tincture of the treatment parrot fish ichthyophthiriasis of the present embodiment is with embodiment 1.
Embodiment 5
A kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 39 parts, Rhizoma Dioscoreae esculentae 33 parts, 32 parts, Fructus Gleditsia, Flos Lonicerae 30 parts, Folium Persicae 30 parts, Radix Sanguisorbae 31 parts, lavandula angustifolia 30 parts, Herba Scutellariae Barbatae 28 parts, Fructus Schisandrae Chinensis 27 parts, Artemisia anethoicles Mattf 24 parts, Herba Patriniae 24 parts, Juncus effusus L. Var.Decipiens Buchen. 23 parts, Herba Cheilanthes chusane 23 parts, 22 parts, catechu, attached column spends 22 parts, smartweed 20 parts, Radix Stephaniae Cepharanthae 19 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Herba Violae 18 parts, 18 parts, Bulbus Allii, Herba Hedyotidis Diffusae 16 parts, Herba Portulacae 15 parts, 14 parts, Rhizoma Zingiberis Recens, bamboo salt 15 parts, Mel 12 parts, hyaluronic acid 4 parts, mass concentration is the ethanol 27 parts of 75%.
The preparation method of the tincture of the treatment parrot fish ichthyophthiriasis of the present embodiment is with embodiment 1.
Embodiment 6
In the present invention's the 6th detailed description of the invention, feed ingredient and preparation method thereof is as follows:
A kind of tincture for the treatment of parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 40 parts, Rhizoma Dioscoreae esculentae 33 parts, 31 parts, Fructus Gleditsia, Flos Lonicerae 31 parts, Folium Persicae 32 parts, Radix Sanguisorbae 30 parts, lavandula angustifolia 28 parts, Herba Scutellariae Barbatae 28 parts, Fructus Schisandrae Chinensis 27 parts, Artemisia anethoicles Mattf 25 parts, Herba Patriniae 25 parts, Juncus effusus L. Var.Decipiens Buchen. 22 parts, Herba Cheilanthes chusane 23 parts, 22 parts, catechu, attached column spends 21 parts, smartweed 21 parts, Radix Stephaniae Cepharanthae 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Herba Violae 17 parts, 17 parts, Bulbus Allii, Herba Hedyotidis Diffusae 16 parts, Herba Portulacae 16 parts, 15 parts, Rhizoma Zingiberis Recens, bamboo salt 14 parts, Mel 13 parts, hyaluronic acid 5 parts, mass concentration is the ethanol 28 parts of 75%.
The preparation method of the tincture of the treatment parrot fish ichthyophthiriasis of the present embodiment is with embodiment 1.
Experimental result
Contrast experiment
Test site is selected in fishing ground, Qingdao, in order to verify therapeutic effect of the present invention, tests the parrot fish suffering from ichthyophthiriasis:
The process of matched group is as follows: water per ton puts into the Sal of 0.5kg-1kg, within every 12 hours, changes water once, adds Sal after changing water by same ratio, until the recovery from illness of sick fish.
The process of experiment A group is as follows: the disease sites tincture of the embodiment of the present invention 1 being applied in disease fish, every day 2 times, until the recovery from illness of sick fish.
The process of experiment B group is as follows: the disease sites tincture of the embodiment of the present invention 2 being applied in disease fish, every day 2 times, until the recovery from illness of sick fish.
The process of experiment C group is as follows: the disease sites tincture of the embodiment of the present invention 3 being applied in disease fish, every day 2 times, until the recovery from illness of sick fish.
The process of experiment D group is as follows: the disease sites tincture of the embodiment of the present invention 4 being applied in disease fish, every day 2 times, until the recovery from illness of sick fish.
The process of experiment E group is as follows: the disease sites tincture of the embodiment of the present invention 5 being applied in disease fish, every day 2 times, until the recovery from illness of sick fish.
The process of experiment F group is as follows: the disease sites tincture of the embodiment of the present invention 6 being applied in disease fish, every day 2 times, until the recovery from illness of sick fish.
Experimental result is in table 1:
The tincture therapeutic effect of table 1 treatment of the present invention parrot fish ichthyophthiriasis
Experimental result shows: the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention is the etiopathogenesis according to ichthyophthiriasis, the suitable component of selection, and is organically combined, and has significant cooperative synergism effect, plays the function of each component to greatest extent.The component of the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention is environmental protection raw material, nontoxic to environment, not containing chemical drugs or antibiotic, and tincture of the present invention is good to the curative effect of parrot fish ichthyophthiriasis, cure rate is high, make the survival rate of ill parrot fish to more than 90%, after medication 1-2 days, parrot fish white point with it can all disappear.In addition, the present invention uses safer, relatively mildly can act on parrot fish, little to parrot fish damage; after using the tincture for the treatment of parrot fish ichthyophthiriasis of the present invention, parrot fish Health restoration is fast, medication 2-4 days; parrot fish can recover normal activity, and idle fund is strong and vigorous, ingests completely normal.
The above is only the preferred embodiment of the present invention, is noted that for those skilled in the art, and under the premise without departing from the principles of the invention, can also make some improvement, these improvement should be considered as protection scope of the present invention.

Claims (4)

1. treat the tincture of parrot fish ichthyophthiriasis for one kind, it is characterized in that: be made up of each component of following masses number: Rhizoma Acori Graminei 36-42 part, Rhizoma Dioscoreae esculentae 30-35 part, Fructus Gleditsia 28-35 part, Flos Lonicerae 28-34 part, Folium Persicae 28-34 part, Radix Sanguisorbae 27-34 part, lavandula angustifolia 25-33 part, Herba Scutellariae Barbatae 24-32 part, Fructus Schisandrae Chinensis 24-30 part, Artemisia anethoicles Mattf 21-27 part, Herba Patriniae 21-27 part, Juncus effusus L. Var.Decipiens Buchen. 20-26 part, Herba Cheilanthes chusane 19-27 part, catechu 19-25 part, attached column flower 18-25 part, smartweed 16-25 part, Radix Stephaniae Cepharanthae 15-23 part, Rhizoma Atractylodis Macrocephalae 15-21 part, Herba Violae 15-21 part, Bulbus Allii 14-21 part, Herba Hedyotidis Diffusae 12-20 part, Herba Portulacae 12-19 part, Rhizoma Zingiberis Recens 12-17 part, bamboo salt 11-17 part, Mel 9-17 part, hyaluronic acid 3-6 part, mass concentration is ethanol 23-32 part of 75%.
2. the tincture for the treatment of parrot fish ichthyophthiriasis according to claim 1, it is characterized in that: the tincture of described treatment parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 39 parts, Rhizoma Dioscoreae esculentae 33 parts, 32 parts, Fructus Gleditsia, Flos Lonicerae 30 parts, Folium Persicae 30 parts, Radix Sanguisorbae 31 parts, lavandula angustifolia 30 parts, Herba Scutellariae Barbatae 28 parts, Fructus Schisandrae Chinensis 27 parts, Artemisia anethoicles Mattf 24 parts, Herba Patriniae 24 parts, Juncus effusus L. Var.Decipiens Buchen. 23 parts, Herba Cheilanthes chusane 23 parts, 22 parts, catechu, attached column spends 22 parts, smartweed 20 parts, Radix Stephaniae Cepharanthae 19 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Herba Violae 18 parts, 18 parts, Bulbus Allii, Herba Hedyotidis Diffusae 16 parts, Herba Portulacae 15 parts, 14 parts, Rhizoma Zingiberis Recens, bamboo salt 15 parts, Mel 12 parts, hyaluronic acid 4 parts, mass concentration is the ethanol 27 parts of 75%.
3. the tincture for the treatment of parrot fish ichthyophthiriasis according to claim 1, it is characterized in that: the tincture of described treatment parrot fish ichthyophthiriasis, be made up of each component of following masses number: Rhizoma Acori Graminei 40 parts, Rhizoma Dioscoreae esculentae 33 parts, 31 parts, Fructus Gleditsia, Flos Lonicerae 31 parts, Folium Persicae 32 parts, Radix Sanguisorbae 30 parts, lavandula angustifolia 28 parts, Herba Scutellariae Barbatae 28 parts, Fructus Schisandrae Chinensis 27 parts, Artemisia anethoicles Mattf 25 parts, Herba Patriniae 25 parts, Juncus effusus L. Var.Decipiens Buchen. 22 parts, Herba Cheilanthes chusane 23 parts, 22 parts, catechu, attached column spends 21 parts, smartweed 21 parts, Radix Stephaniae Cepharanthae 18 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Herba Violae 17 parts, 17 parts, Bulbus Allii, Herba Hedyotidis Diffusae 16 parts, Herba Portulacae 16 parts, 15 parts, Rhizoma Zingiberis Recens, bamboo salt 14 parts, Mel 13 parts, hyaluronic acid 5 parts, mass concentration is the ethanol 28 parts of 75%.
4. a preparation method for the tincture of the treatment parrot fish ichthyophthiriasis according to any one of claim 1-3, is characterized in that: comprise the following steps:
(1) take Rhizoma Acori Graminei, Rhizoma Dioscoreae esculentae, Fructus Gleditsia, Flos Lonicerae, Folium Persicae, Radix Sanguisorbae, lavandula angustifolia, Bulbus Allii, Rhizoma Zingiberis Recens according to proportioning, gross weight is designated as 1 part, adds 8 parts of purified water, and 40-50 DEG C is soaked 1h, obtain soak;
(2) boil 2h after the soak that step (1) obtains being heated to boiling, be separated and take out fried liquid, continue the purified water adding 4 parts in medical material, continue to boil 1.5h after being heated to boiling, merge twice fried liquid and be extracting solution;
(3) take the Rhizoma Atractylodis Macrocephalae, Herba Violae, Herba Hedyotidis Diffusae and Herba Portulacae respectively according to proportioning, load ball mill grinding 2h, cross 80 mesh sieves, obtain grounds travel;
(4) Herba Scutellariae Barbatae, Fructus Schisandrae Chinensis, Artemisia anethoicles Mattf, Herba Patriniae, Juncus effusus L. Var.Decipiens Buchen., Herba Cheilanthes chusane, catechu, attached column flower, smartweed and Radix Stephaniae Cepharanthae is taken according to proportioning, and mix, the Pulvis concha Mactrae that weight is 1/2nd of mixed powder gross weight is added in mixed powder, 120 ~ 160 DEG C of parches of advancing after adding Pulvis concha Mactrae, after parch completes, remove Pulvis concha Mactrae, then put into pulverizer and pulverize and cross 100 mesh sieves, obtain comminuted powder;
(5) take according to proportioning the ethanol that mass concentration is 75%, the grounds travel that the extracting solution obtain step (2) and step (3) obtain, the comminuted powder of step (4) gained and load weighted ethanol are positioned in the extraction kettle in supercritical extraction instrument, carbon dioxide is utilized to extract as medium, extraction kettle pressure is 40Mpa, extraction temperature is 45 DEG C, separator pressure 12Mpa, and separator temperature is 70 DEG C, extract 2 hours, be extracted liquid;
(6) take bamboo salt, Mel and hyaluronic acid respectively according to proportioning, and mix homogeneously with the extract of step (5) gained, obtain object.
CN201510861535.2A 2015-11-30 2015-11-30 Tincture for treating ichthyophthiriasis of parrotfish and preparation method of tincture for treating ichthyophthiriasis of parrotfish Pending CN105362993A (en)

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Application publication date: 20160302