CN104138541A - Chinese herbal preparation for curing cobra respiratory system disease and producing method thereof - Google Patents
Chinese herbal preparation for curing cobra respiratory system disease and producing method thereof Download PDFInfo
- Publication number
- CN104138541A CN104138541A CN201410372139.9A CN201410372139A CN104138541A CN 104138541 A CN104138541 A CN 104138541A CN 201410372139 A CN201410372139 A CN 201410372139A CN 104138541 A CN104138541 A CN 104138541A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- naja
- radix
- respiratory system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 32
- 208000023504 respiratory system disease Diseases 0.000 title claims abstract description 19
- 238000000034 method Methods 0.000 title claims abstract description 4
- 241000270295 Serpentes Species 0.000 title abstract description 9
- 241000746375 Andrographis Species 0.000 claims abstract description 19
- 239000010231 banlangen Substances 0.000 claims abstract description 19
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 241000167550 Centella Species 0.000 claims abstract description 9
- 239000003814 drug Substances 0.000 claims description 62
- 241000272041 Naja Species 0.000 claims description 46
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 30
- 241000628997 Flos Species 0.000 claims description 25
- 239000000706 filtrate Substances 0.000 claims description 15
- 239000008213 purified water Substances 0.000 claims description 15
- 241000272060 Elapidae Species 0.000 claims description 13
- 239000007788 liquid Substances 0.000 claims description 13
- 239000003651 drinking water Substances 0.000 claims description 11
- 235000020188 drinking water Nutrition 0.000 claims description 11
- 238000010992 reflux Methods 0.000 claims description 11
- 238000004519 manufacturing process Methods 0.000 claims description 9
- 241000245240 Lonicera Species 0.000 claims description 8
- 239000000047 product Substances 0.000 claims description 7
- 230000001186 cumulative effect Effects 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000003449 preventive effect Effects 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 16
- 206010059866 Drug resistance Diseases 0.000 abstract description 3
- 235000017166 Bambusa arundinacea Nutrition 0.000 abstract description 2
- 235000017491 Bambusa tulda Nutrition 0.000 abstract description 2
- 235000015334 Phyllostachys viridis Nutrition 0.000 abstract description 2
- 239000011425 bamboo Substances 0.000 abstract description 2
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241001330002 Bambuseae Species 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 231100000614 poison Toxicity 0.000 description 10
- 208000024891 symptom Diseases 0.000 description 10
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 229940079593 drug Drugs 0.000 description 9
- 201000010099 disease Diseases 0.000 description 8
- 201000007100 Pharyngitis Diseases 0.000 description 7
- 241000345998 Calamus manan Species 0.000 description 6
- 210000000214 mouth Anatomy 0.000 description 6
- 230000001737 promoting effect Effects 0.000 description 6
- 235000012950 rattan cane Nutrition 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 5
- 206010068319 Oropharyngeal pain Diseases 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 5
- 210000003128 head Anatomy 0.000 description 5
- 239000003440 toxic substance Substances 0.000 description 5
- 244000025254 Cannabis sativa Species 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 4
- 206010013975 Dyspnoeas Diseases 0.000 description 4
- 241000334154 Isatis tinctoria Species 0.000 description 4
- 241000700605 Viruses Species 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 230000008673 vomiting Effects 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 3
- COHYTHOBJLSHDF-UHFFFAOYSA-N Indigo Chemical compound N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 3
- 240000000249 Morus alba Species 0.000 description 3
- 235000008708 Morus alba Nutrition 0.000 description 3
- 235000014676 Phragmites communis Nutrition 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 206010043458 Thirst Diseases 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 230000008034 disappearance Effects 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 239000003172 expectorant agent Substances 0.000 description 3
- 230000003419 expectorant effect Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 241000411851 herbal medicine Species 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 238000002955 isolation Methods 0.000 description 3
- 230000003340 mental effect Effects 0.000 description 3
- 210000003097 mucus Anatomy 0.000 description 3
- 239000002574 poison Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 230000001047 pyretic effect Effects 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- WQZGKKKJIJFFOK-SVZMEOIVSA-N (+)-Galactose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-SVZMEOIVSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 206010003591 Ataxia Diseases 0.000 description 2
- 235000004032 Centella asiatica Nutrition 0.000 description 2
- 244000146462 Centella asiatica Species 0.000 description 2
- MKMCJLMBVKHUMS-UHFFFAOYSA-N Coixol Chemical compound COC1=CC=C2NC(=O)OC2=C1 MKMCJLMBVKHUMS-UHFFFAOYSA-N 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 201000000297 Erysipelas Diseases 0.000 description 2
- 208000034507 Haematemesis Diseases 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 244000283207 Indigofera tinctoria Species 0.000 description 2
- 235000000177 Indigofera tinctoria Nutrition 0.000 description 2
- 208000001705 Mouth breathing Diseases 0.000 description 2
- 244000273256 Phragmites communis Species 0.000 description 2
- 240000005827 Phyllostachys nigra Species 0.000 description 2
- 235000010717 Phyllostachys nigra Nutrition 0.000 description 2
- 206010035664 Pneumonia Diseases 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 241000934136 Verruca Species 0.000 description 2
- 208000000260 Warts Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 240000003248 Zanthoxylum nitidum Species 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- 239000002642 cobra venom Substances 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 230000009193 crawling Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 206010015037 epilepsy Diseases 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 238000013467 fragmentation Methods 0.000 description 2
- 238000006062 fragmentation reaction Methods 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 210000004209 hair Anatomy 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 description 2
- 208000005264 motor neuron disease Diseases 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 239000002304 perfume Substances 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 201000010153 skin papilloma Diseases 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- UUTKICFRNVKFRG-WDSKDSINSA-N (4R)-3-[oxo-[(2S)-5-oxo-2-pyrrolidinyl]methyl]-4-thiazolidinecarboxylic acid Chemical compound OC(=O)[C@@H]1CSCN1C(=O)[C@H]1NC(=O)CC1 UUTKICFRNVKFRG-WDSKDSINSA-N 0.000 description 1
- HRGUSFBJBOKSML-UHFFFAOYSA-N 3',5'-di-O-methyltricetin Chemical compound COC1=C(O)C(OC)=CC(C=2OC3=CC(O)=CC(O)=C3C(=O)C=2)=C1 HRGUSFBJBOKSML-UHFFFAOYSA-N 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 244000118350 Andrographis paniculata Species 0.000 description 1
- 241000180579 Arca Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 241001164374 Calyx Species 0.000 description 1
- 235000001808 Ceanothus spinosus Nutrition 0.000 description 1
- 241001264786 Ceanothus spinosus Species 0.000 description 1
- 241001597062 Channa argus Species 0.000 description 1
- 241000258920 Chilopoda Species 0.000 description 1
- 206010009152 Chronic tonsillitis Diseases 0.000 description 1
- 241001518926 Cladrastis Species 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 241001573881 Corolla Species 0.000 description 1
- 241001137251 Corvidae Species 0.000 description 1
- 241000125183 Crithmum maritimum Species 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 1
- 206010012335 Dependence Diseases 0.000 description 1
- 206010012374 Depressed mood Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 208000004145 Endometritis Diseases 0.000 description 1
- 208000035126 Facies Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000005577 Gastroenteritis Diseases 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010019345 Heat stroke Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 244000202566 Hydrocotyle vulgaris Species 0.000 description 1
- 235000015916 Hydrocotyle vulgaris Nutrition 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000029523 Interstitial Lung disease Diseases 0.000 description 1
- 241000334160 Isatis Species 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- SRBFZHDQGSBBOR-HWQSCIPKSA-N L-arabinopyranose Chemical compound O[C@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-HWQSCIPKSA-N 0.000 description 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
- 241000270322 Lepidosauria Species 0.000 description 1
- 241000100289 Lonicera confusa Species 0.000 description 1
- 244000167230 Lonicera japonica Species 0.000 description 1
- 235000017617 Lonicera japonica Nutrition 0.000 description 1
- 241001570521 Lonicera periclymenum Species 0.000 description 1
- 241000218231 Moraceae Species 0.000 description 1
- 208000026072 Motor neurone disease Diseases 0.000 description 1
- 208000005647 Mumps Diseases 0.000 description 1
- 241000117280 Naematelia aurantialba Species 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- 206010033078 Otitis media Diseases 0.000 description 1
- 206010033645 Pancreatitis Diseases 0.000 description 1
- 241000282376 Panthera tigris Species 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 1
- 241000382362 Persicaria tinctoria Species 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- IDDMFNIRSJVBHE-UHFFFAOYSA-N Piscigenin Natural products COC1=C(O)C(OC)=CC(C=2C(C3=C(O)C=C(O)C=C3OC=2)=O)=C1 IDDMFNIRSJVBHE-UHFFFAOYSA-N 0.000 description 1
- 208000032319 Primary lateral sclerosis Diseases 0.000 description 1
- 241000015864 Protobothrops flavoviridis Species 0.000 description 1
- 206010037423 Pulmonary oedema Diseases 0.000 description 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 206010039587 Scarlet Fever Diseases 0.000 description 1
- 241000239226 Scorpiones Species 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 244000061458 Solanum melongena Species 0.000 description 1
- 241000257673 Strobilanthes cusia Species 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 206010046298 Upper motor neurone lesion Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 241000271897 Viperidae Species 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229910000004 White lead Inorganic materials 0.000 description 1
- 206010048245 Yellow skin Diseases 0.000 description 1
- YADZBEISHVCBSJ-UHFFFAOYSA-N [I].OCC(O)CO Chemical compound [I].OCC(O)CO YADZBEISHVCBSJ-UHFFFAOYSA-N 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 208000012873 acute gastroenteritis Diseases 0.000 description 1
- 208000016150 acute pharyngitis Diseases 0.000 description 1
- 206010001093 acute tonsillitis Diseases 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 201000007201 aphasia Diseases 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000000812 cholinergic antagonist Substances 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000000039 congener Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000005560 droplet transmission Effects 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000010196 hermaphroditism Effects 0.000 description 1
- 230000006266 hibernation Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 239000010903 husk Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 229940097275 indigo Drugs 0.000 description 1
- COHYTHOBJLSHDF-BUHFOSPRSA-N indigo dye Chemical compound N\1C2=CC=CC=C2C(=O)C/1=C1/C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-BUHFOSPRSA-N 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 201000010901 lateral sclerosis Diseases 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000005541 medical transmission Effects 0.000 description 1
- 101150087532 mitF gene Proteins 0.000 description 1
- 229960005181 morphine Drugs 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 208000010805 mumps infectious disease Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 201000008752 progressive muscular atrophy Diseases 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 208000005333 pulmonary edema Diseases 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 206010037833 rales Diseases 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 201000004193 respiratory failure Diseases 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- 230000000405 serological effect Effects 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 210000002356 skeleton Anatomy 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000002048 spasmolytic effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 230000001550 time effect Effects 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- BMCJATLPEJCACU-UHFFFAOYSA-N tricin Natural products COc1cc(OC)c(O)c(c1)C2=CC(=O)c3c(O)cc(O)cc3O2 BMCJATLPEJCACU-UHFFFAOYSA-N 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000002435 venom Substances 0.000 description 1
- 210000001048 venom Anatomy 0.000 description 1
- 231100000611 venom Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 229920001221 xylan Polymers 0.000 description 1
- 150000004823 xylans Chemical class 0.000 description 1
- 235000007063 yellowwood Nutrition 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Chinese herbal preparation for curing cobra respiratory system disease comprises the following raw materials, by weight proportion, of 5-7 parts of common andrographis herb, 10-12 parts of folium mori, 3-5 parts of radix zanthoxyli, 3-5 parts of honeysuckle, 6-8 parts of radix isatidis, 8-10 parts of centella, 12-14 parts of bamboo leaf and 15-17 parts of rhizome phragmitis. A producing method of the Chinese herbal preparation comprises the steps of reversely flowing, decocting, purifying and concentrating traditional Chinese herb. The Chinese herbal preparation has the advantages of being small in side effect, free of drug resistance and obvious in curing effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation about Naja disease and production method thereof, relate in particular to a kind of Chinese medicine preparation and production method thereof of preventing and treating Naja respiratory system disease.
Background technology
Naja (Latin formal name used at school: Naja) is commonly called as habu, meal spoon blunderbuss, five poisonous creatures: scorpion, viper, centipede, house lizard, toad Serpentis, is the general name of Serpentis class under Elaps, the general name of some the Serpentis classes in Shi She section, be mainly distributed in Asia, Africa subtropical and tropical zones.And refrigerant latitudes is little, the most obvious feature of Naja is cervical region, and while being on the hazard, the upright neck abdominal part of snakehead is extended to round fan-shaped.During because of its cervical region skin pleat expansion, back can present the magpie of a pair of beauty, seems glasses shape decorative pattern, therefore named Naja.
Naja whole body is all precious, and economic worth is very high, and in recent years, Naja is that supply falls short of demand on market always.This Carnis Serpentis delicious flavour, is rich in nutrition, and internal organs, skeleton, blood, bile and attaching organism all can be used as medicine, and especially cobra venom has now been made analgesic, and its analgesic effect is good, and without addiction, can replace the addictive drugs such as morphine.In addition, cobra venom preparation, to treatment motor neuron disease, as progressive spinal muscular atrophy disease, primary lateral sclerosis etc., has good curative effect.Visible, Naja is indispensable ingredient in China's Chinese medicine treasure-house.
Along with socioeconomic development, people are increasing to elapid demand, but ecological environment constantly destroyed, and add artificial catching and killing in a large number, peddle, and wild elapid resource is fallen sharply, and some local Naja is endangered.How to adopt an effective measure and protect existing wild Naja, exploitation artificial cultivation Naja resource, maintaining ecological balance has become the task of top priority.
The Naja of artificial cultivation because high humidity, the temperature of environment is high, suddenly cold and hot and when stuffy, subject to courses of infection and suffer from respiratory system disease.Relatively common are acute pneumonia, Serpentis humidity in duration of hibernation nest heat in high or midsummer, in nest all easily there is this disease in too sultry or sudden drop in temperature.Can be caused by flu in early days.When raising sanitation and hygiene are poor, this sick sickness rate is high, and this disease transmission obtains soon, if treatment not in time can infect group entirely in 3-5 days sometimes, causes large quantities of death.Also have the respiratory system disease being caused by virus, this disease is a kind of very serious disease to Serpentis.In majority of cases, can from Electronic Speculum, observe or be separated to a kind of virus that is called Paramyxo virus.This sick mortality rate is 8% one 87%, and aged Serpentis susceptible, by saliva droplet transmission, infects within latter 3 days and show clinical symptoms. stadium is about 5-12 days.The symptom in early stage of sick Serpentis is: do not urinate, vomit, arrange the green feces with mucus; There is subsequently obvious clinical symptoms: the elasticity of muscle disappears (Serpentis body is extended configuration), head chatter, ataxia.Finally, there is Respiratory symptoms: suddenly respiratory standstill, then there is spasm tempestuously, health is sloughed off contracting together, discharges brown secretions in trachea.The secondary inspection of corpse is visible, and pulmonary edema has mucus or in cheese sexual secretion.Histopathological examination can be seen the interstitial pneumonia with epithelial hyperplasia, blood vessel office mouth sleeve encephalitis and pancreatitis.The resistance to Serological testing of crossing Serpentis can be found the antibody of existence.
This type of Naja respiratory system disease is one of principal disease affecting the development of Naja artificial cultivation industry, causes huge loss to Naja artificial cultivation industry.The main antibiotics that adopts prevents and treats at present, but easily produces drug resistance and drug residue, and Serpentis is also had to certain infringement, uses for a long time, and therapeutic effect can decline gradually.
Summary of the invention
Based on the problem that has at present above-mentioned existence, the invention provides a kind of Chinese medicine preparation and production method thereof of preventing and treating Naja respiratory system disease.The present invention have toxic and side effects little, do not produce drug resistance, there is the feature of obvious therapeutical effect.
The present invention realizes by the following technical solutions:
The Chinese medicine preparation of control Naja respiratory system disease, it comprises the raw material of following weight proportioning: 5 parts-7 parts of Herba Andrographis, 10 parts-12 parts, Folium Mori, 3 parts-5 parts of Radix Zanthoxylis, 3 parts-5 parts of Flos Loniceraes, 6 parts-8 parts of Radix Isatidis, 8 parts-10 parts of Herba Centellaes, 12 parts-14 parts, Folium Bambusae, Rhizoma Phragmitis 15-17 part.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 6 parts of Herba Andrographis, 11 parts, Folium Mori, 4 parts of Radix Zanthoxylis, 4 parts of Flos Loniceraes, 7 parts of Radix Isatidis, 9 parts of Herba Centellaes, 13 parts, Folium Bambusae, 16 parts of Rhizoma Phragmitiss.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 5 parts of Herba Andrographis, 10 parts, Folium Mori, 3 parts of Radix Zanthoxylis, 3 parts of Flos Loniceraes, 6 parts of Radix Isatidis, 8 parts of Herba Centellaes, 12 parts, Folium Bambusae, 15 parts of Rhizoma Phragmitiss.
Preferably, the weight portion proportioning of each raw material of Chinese medicine is: 7 parts of Herba Andrographis, 12 parts, Folium Mori, 5 parts of Radix Zanthoxylis, 5 parts of Flos Loniceraes, 8 parts of Radix Isatidis, 10 parts of Herba Centellaes, 14 parts, Folium Bambusae, 17 parts of Rhizoma Phragmitiss.
The Chinese medicine preparation of described control Naja respiratory system disease, the production method of its Chinese medicine preparation comprises following steps:
Step 1) takes by weight Herba Andrographis, Folium Mori, Radix Zanthoxyli, Flos Lonicerae, Radix Isatidis, Herba Centellae, Folium Bambusae, Rhizoma Phragmitis and pulverizes respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
The Chinese medicine preparation of described control Naja respiratory system disease, the using method of its Chinese medicine preparation is: the finished product of having produced is applied to elapid feedstuff or joins in elapid normal drinking water and evenly mix, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
In the raw material of Chinese medicine that the present invention chooses, each medicine active ingredient is analyzed:
Herba Andrographis is acanthaceous plant.Herba Andrographis (formal name used at school: Andrographis paniculata (Burm. f.) Nees), has another name called Chun Lianqiuliu, Herba Andrographitis, Lan Helian, Radix Gentianae, golden Rhizoma et radix valerianae, Tremella aurantialba Bandoni et Zang hook, India's grass, Herba vallisneriae Spiralis etc.Annual herb plant, stem is square column type, multi-branched, long 50～70cm, joint slightly expands; Matter is crisp, frangibility.Single leaf is to life, the short or nearly stockless of petiole; Leaf-shrinkage, frangible, complete person is lanceolar or ovum shape lanceolar after launching, long 3～12cm, wide 2～5cm, tip is point gradually, and base portion wedge shape is downward, full edge or wavy; Upper surface green, lower surface celadon, two sides is smooth.Feeble QI, taste is extremely bitter.When stem and leaf is luxuriant at the beginning of autumn, tap the part that Herba Andrographis is gone up dryly, dry.Medicinal plants, has heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain effect.Herba Andrographis has eliminating inflammation and expelling toxin effect, once be applied to clinically multi-infection disease, comprise trauma infection contamination, furuncle, carbuncle, erysipelas, upper respiratory tract infection, acute and chronic tonsillitis, acute and chronic pharyngitis, acute/chronic bronchitis, acute bacillary dysentery, acute gastroenteritis, urinary tract infection, endometritis, pelvic inflammatory disease, otitis media, periodontitis etc., all have curative effect in various degree.
Folium Mori, Chinese medicine name, English name: Mulberry Leaf, medical material formal name used at school: Folium Mori is the dried leaves of moraceae plants Mulberry, has another name called a Mulberry, Jing Sang, Fructus Mori tree, yellow wood etc., and there is production national most areas more.The many shrinkages of Folium Mori, fragmentation.Complete person has handle, and blade is avette or width egg shape after flattening, long 8～15cm, wide 7～13cm; Tip is point gradually, and base portion cuts shape, circle or heart-shaped, and there are sawtooth or crenation in edge, the irregular division having.Upper surface yellow green or light yellowish brown, what have has a little verruca; Lower surface color is slightly shallow, and vein is outstanding, and scun is netted, on arteries and veins, is dredged hair, arteries and veins base tool tuft.Matter is crisp.Feeble QI, lightly seasoned, micro-bitterness.Have the effects such as blood pressure lowering, blood fat, antiinflammatory, major function is dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Ministry of Public Health in 1993 determines that Folium Mori are food and medicine.Fructus Mori when children fruit viridescent, purple, aubergine darkly after maturation, sweet and sour is good to eat.
Radix Zanthoxyli (formal name used at school: Zanthoxylum nitidum(Roxb.) DC.) another name: nail-plate thorn (Foochow), enter under mountain tiger, anaesthetic rattan, Radix Zanthoxyli, leaf to thread a needle, the red le of falling hook, great Ye cat pawl le (Guangdong, Guangxi), red heart Zanthoxylum nitidum (Roxb.) DC, it is bejuco, be sheet or cylindrical short section, long 2～20cm, thick 0.5～6(10) cm.Surface light brown yellow or faint yellow, has foresythia or yellowish-brown similar round hole skin.Section is more smooth, skin zone's light brown, and woody part is faint yellow, visible proper alignment ring grain and intensive aperture.Matter is hard.Feeble QI perfume (or spice), the peppery numb tongue of acrid in the mouth and hardship.All can excavate the whole year, cleans, and section or section, dry.Nature and flavor: bitter, pungent, flat; Slightly poisonous.Function cures mainly: promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral.The traumatic injury, rheumatic arthralgia, stomachache, the toothache that cause for qi depression to blood stasis, venom; The burning hot wound of external treatment soup.
Flos Lonicerae, has another name called Radix Ophiopogonis (formal name used at school: Lonicera japonica).Another name Caulis Lonicerae, silvernine, two color flower rattans, two precious rattans, right-hand rotation rattan, sub-Radix seu Caulis fici Martinii, Aicis galericulata rattan, Flos Lonicerae." Flos Lonicerae " one come from Compendium of Material Medica, because Flos Lonicerae is just opened as white, after transfer yellow to, Flos Lonicerae hence obtains one's name.Medical material Flos Lonicerae is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or the first flower of opening of band.Flos Lonicerae, bloom March, and five go out, micro-perfume (or spice), redly, Hua Chukai color is white for the base of a fruit, the yellow skin through, two day, therefore named Flos Lonicerae.Because a base of a fruit Flos Lonicerae, two pistils are visited outside again, in pairs, on very close terms, and shape is as female in hero together, again like Aicis galericulata to waving, therefore there is the title of Aicis galericulata rattan.This kind is the most significantly characterised in that the lobate bract with large shape.It is some resembles Lonicera confusa in person, but the bract of that kind is narrow thin but not lobate, the close raw pubescence of calyx tube, and the pubescence that the close life of sprig is curling, obvious different from this kind.The morphological variation of this kind is very large, no matter, at aspects such as the length ratios of fleece, the shape of leaf and length, fleece and the lip of size and corolla and the cylinder portion of branch, leaf, all varies widely.But it seems that all these variations more contact with ecological environment facies, shows the dependency between geographical distribution.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times.The sweet cold fragrance of its property, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil.Flos Lonicerae can dispelling wind-heat, also kind removing summer-heat blood poison, and for various febrile diseases, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.
The conventional another name of Radix Isatidis (Isatis tinctoria): indigo-blue, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root, Radix Clerodenri Cyrtophylli are a kind of Chinese crude drugs.Cylindrical, slightly distortion, long 10～20cm, diameter 0.5～1cm.The light lark in surface or light brown yellow, have vertical wrinkle and supporting root trace, and hole skin is grown crosswise.Root head slightly expands, the petiole residual base that visible dirty-green or burgundy colyliform are arranged and intensive verruca.Body is real, and matter is slightly soft, section skin zone yellow-white, woody part yellow.Feeble QI, the micro-sweet rear bitterness of taste.Excavate autumn, removes silt, dries.All produce all over China.Radix Isatidis is divided into northern Radix Isatidis and Rhizoma Et Radix Baphicacanthis Cusiae, the root that northern Radix Isatidis source is cruciferae isatis (Isatis tinctoria L.) and careless Folium Isatidis (I. indigotica Fort.); Rhizoma Et Radix Baphicacanthis Cusiae is rhizome and the root of acanthaceous vegetable acanthaceous indigo (Baphicacanthus cusia (Nees) Brem.).There is heat-clearing and toxic substances removing, effect of removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.
Herba Centellae is the dry herb of samphire Herba Centellae Centella asiatica (L.) Urb., is the perennial draft of crawling.Another name: 18 lack, collapse jorum, Herba Calthae Membranaceae, Gotu Kola, Carnis Arca inflata shell grass, Hydrocotyle vulgaris L., Herba sambuci chinensis.Be born in by dark and damp wasteland, village, roadside, limit, ditch.Often crispatura into bulk.Root is cylindrical, long 2～4cm, diameter 1～1.5mm, the light yellow or lark in surface.Stem elongate curved, yellowish-brown, has thin vertical wrinkle, normal the palpus shape root of giving birth to joint on.The many shrinkages of blade, fragmentation, complete person is subcircular or kidney shape after flattening, diameter 1～4cm, celadon, there is thick cognate at edge; Long 3～the 6cm of petiole, distortion.Umbel axil is raw, short and small.Diachenium oblateness, has vertical rib and the fine-structure mesh stricture of vagina of obvious protuberance, and carpopodium is very short.Feeble QI, lightly seasoned.Summer, Qiu Erji gather, and remove silt, dry.Function cures mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.For jaundice due to damp-heat, heatstroke diarrhoea, sand Stranguria stranguria with blood, carbuncle sore tumefacting virus, injury from falling down.
Folium Bambusae (Phyllostachys nigra (Lodd.) Munro var. henonis (Mitf.) Stapf ex Rendle) is the leaf of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle (bamboo).Effect of Folium Bambusae: clearing heat and relieving fidgetness, the diuresis of promoting the production of body fluid.Control calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea is told nosebleed, flushed complexion, oliguria also, erosion of the oral mucosa tongue boil.1. not " not Lu ": main expectorant heat in the heart, cough with dyspnea.2. " property of medicine opinion ": main haematemesis pyretic toxicity wind, only quench one's thirst.3. " Treatise on Dietetic Therapy ": main cough with dyspnea, quench one's thirst, phlegm retention, sore throat, heat clearing away and restlessness relieving.4. " Japan hanako materia medica ": expectorant, control fanatical unhappiness, apoplectic aphasia in silence, high fever, headache wind syndrome of head, and cherish the pregnant number of people and revolve and fall down to the ground, spasmolytic is throbbed with fear, pestilence fan is vexed, pediatric epilepsy scared sky hangs.5. Zhang Yuansu: cool heart channel, beneficial vigour, heat extraction, slow spleen.6. " detailed outline ": decoct extract, gargle in tooth hemorrhagely, eluting anus is not received.7. " book on Chinese herbal medicine is just ": the irritated sleeplessness of reducing the asthenic fever, only excessive thirst, born fluid, Li little Shui, separates sore throat, and children's wind-heat infantile convulsion.8. " Chongqing hall random notes ": the wind of interior breath liver and gall, the heat of outer clear temperature administration, therefore there is the merit of the relieving convulsion of calming the nerves.9. " book on Chinese herbal medicine is new again ": cool heart spleen invigorating, control haematemesis, nose bleeding, hearing-improing and eyesight improving.
Rhizoma Phragmitis is the fresh or dry rhizome of grass phragmites communis Phragmites communis Trin..Another name: reed root, reed head.Perennial tall and big draft, has the shape of crawling subterraneous stem, sturdy, horizontal walk, internode hollow, tool bud on every joint.Stem is high 2～5 meters, the lower common tool white lead of joint.Leaf 2 row formulas are arranged, tool sheath; Sheath is embraced stem, without hair or tool fine, soft fur; Leaf celadon or aeruginous, wider, wire lanceolar, long 30～60 centimetres, wide 2～5 centimetres, coarse, tip is point gradually; Long 1～2 millimeter of the tip of a leaf, becomes one to take turns a mao shape.The large shape of panicle, top is raw, upright, sometimes slightly bending, and long 15～25 centimetres, sometimes or longer; Long 9～12 millimeters of small ear, mulberry or brown purple, rare faint yellow; Grain husk lanceolar, inner glume is about 1 times than coetonium; The 1st flower is generally male, long 8～15 millimeters of its lemma, and long 3～4 millimeters of glumelle, coarse on ridge; Long 9～16 millimeters of the 2nd lemma, the long gradually point of tip, the pubescence that basal disc tool is long 6～12 millimeters; Hermaphrodite flower tool stamen 3, gynoecium 1, style 2, stigma pinniform.Caryopsis, oval to Long Circle, separate with flower glume.9～October of florescence.Grow in river, bank, pond shallow water.All there is distribution the greater part, the whole nation.All can excavate the whole year, removes bud, fibrous root and membranaceous leaf, using fresh herb or dry.Rhizoma Phragmitis is containing Coixol, and protein 5%, fat 1%, carbohydrate 51%, asparagine 0.1%.Phragmites communis cellulose 48～54%, lignin approximately 18.2%, xylan approximately 12.4%, ash 2.8%.Polysaccharide hydrolysis produces D-xylose, L-arabinose, D-Glucose, D-galactose and two kinds of alduronic acid.Another containing volume vitamin B1, B2 and C, and tricin.Function cures mainly: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, the gastric heat sound of vomiting of vomitting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Beneficial effect of the present invention is:
1, Chinese medicine preparation of the present invention has advantages of natural, safe, low (or nothing) poison, efficient, raising immunity of organisms compared to existing technology, can adjust the imbalance state of body, reaches effect for the treatment of both the principal and secondary aspects of a disease;
2, Chinese medicine preparation of the present invention, can be used in the treatment of elapid respiratory system disease, and it adopts Chinese herbal medicine formula, and noresidue medicine after curing, has ensured the safety of medicine;
3, cheaper, the instant effect of Chinese medicine preparation expense of the present invention, curative effect is short, and cure rate is high;
4, Chinese medicine preparation of the present invention forms Herba Andrographis, Folium Mori, Radix Zanthoxyli, Flos Lonicerae, Radix Isatidis, Herba Centellae, Folium Bambusae, Rhizoma Phragmitis through the decoction concentration contracting that refluxes, there is the effects such as heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain, removing summer-heat blood poison, removing heat from blood sore-throat relieving, thereby reached the effect of control Naja respiratory system disease.
Detailed description of the invention
Embodiment 1
Step 1) takes Herba Andrographis 6 kg, Folium Mori 11 kg, Radix Zanthoxyli 4 kg, Flos Lonicerae 4 kg, Radix Isatidis 7 kg, Herba Centellae 9 kg by weight, Folium Bambusae 13 kg, Rhizoma Phragmitis 16 kg pulverize respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
Usage: be applied to elapid feedstuff or join in elapid normal drinking water evenly and mix, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
Embodiment 2
Step 1) takes Herba Andrographis 5 kg, Folium Mori 10 kg, Radix Zanthoxyli 3 kg, Flos Lonicerae 3 kg, Radix Isatidis 6 kg, Herba Centellae 8 kg by weight, Folium Bambusae 12 kg, Rhizoma Phragmitis 15 kg pulverize respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
Usage: be applied to elapid feedstuff or join in elapid normal drinking water evenly and mix, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
Embodiment 3
Step 1) takes Herba Andrographis 7 kg, Folium Mori 12 kg, Radix Zanthoxyli 5 kg, Flos Lonicerae 5 kg, Radix Isatidis 8 kg, Herba Centellae 10 kg by weight, Folium Bambusae 14 kg, Rhizoma Phragmitis 17 kg pulverize respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
Usage: be applied to elapid feedstuff or join in elapid normal drinking water evenly and mix, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake, the preventive dose use that reduces by half.
Case study on implementation:
Case one: large quantities of death appears in foster Serpentis field, Chongzuo, Guangxi 136 age in days Naja, full group more than totally 1200 Serpentis, there is nearly 600 Naja morbidity, 37 Naja of dead, most of Naja disease just shows as mouth breathing, and head is miter angle with ground, spits out white foams, great quantity of water drinking, pants with " sound of flapping " sound of oppressiveness.Inappetence, slow in action, be reluctant to return nest, to open in visible oral cavity, oral cavity and have sticky expectorant but not red and swollen, the frequency of not prolonged illness Serpentis mouth breathing increases, and, there is ataxia in the sick Serpentis health that often reverses.There is spasm latter stage, last respiratory failure death.The Chinese medicine preparation that the application embodiment of the present invention one is produced is treated, and within first 3 days, carries out full group's drinking-water, every day 3 times, each 0.5mL, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake taking medicinal liquid as drinking-water.Do not drink water the sick Serpentis feedstuff feeding of smearing Chinese medicine preparation for isolation, before and after treatment, She Chang and surrounding are carried out to strict sterilization processing.Medication increase morbidity Naja, the clinical symptoms of sick Serpentis and mental status improvement again of full group afterwards in 3 days.After medication 5 days, 541 Naja clinical symptom disappearance, get well substantially, and cure rate reaches more than 95%.Cure after one month and pay a return visit, do not recur again.
Case two: the state of an illness appears in the Naja of certain body raiser's of Binyang, Guangxi more than 550 213 ages in days, approximately 300 Naja are breathed rale sounds, dehisce not close, and 3 is dyspnea due to pulmonary infection after diagnosing.The Chinese medicine preparation that the application embodiment of the present invention two is produced is treated, and within first 3 days, carries out full group's drinking-water, every day 3 times, each 0.5mL, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake taking medicinal liquid as drinking-water.Do not drink water the sick Serpentis feedstuff feeding of smearing Chinese medicine preparation for isolation, before and after treatment, She Chang and surrounding are carried out to strict sterilization processing.After medication 3 days, think except 15 Naja of morbidity Serious Mortality, Quan Qunwei increases morbidity Naja again, and the clinical symptoms of sick Serpentis and the mental status take a turn for the better.After medication 5 days, 285 Naja clinical symptom disappearance, get well substantially, and cure rate reaches 95%.Cure after one month and pay a return visit, do not recur again.
Case three: the state of an illness appears in the Naja of more than 800 180 ages in days of Guigang, Guangxi She Chang, has in more than 80 Naja oral cavity and has a large amount of mucus or purulent secretion, and their early stage, rinses the mouth to Serpentis, is coated with iodine glycerol, ichthyol etc.But the state of an illness does not have controlled, develop into pneumonia, and be transmitted to gradually Naja group.Successively there is more than 450 Naja ill during this period, dead 38 Naja.The Chinese medicine preparation that the application embodiment of the present invention three is produced is treated, and within first 3 days, carries out full group's drinking-water, every day 3 times, each 0.5mL, 1.5～3 grams/bar of serpent intake, 0.8～1.6 gram/bar of little Serpentis intake taking medicinal liquid as drinking-water.Do not drink water the sick Serpentis feedstuff feeding of smearing Chinese medicine preparation for isolation, before and after treatment, She Chang and surrounding are carried out to strict sterilization processing.Medication increase morbidity Naja, the clinical symptoms of sick Serpentis and mental status improvement again of full group afterwards in 3 days.After medication 5 days, 400 Naja clinical symptom disappearance, get well substantially, and cure rate reaches more than 95%.Cure after one month and pay a return visit, do not recur again.
Claims (6)
1. prevent and treat the Chinese medicine preparation of Naja respiratory system disease for one kind, it is characterized in that, it comprises the raw material of following weight proportioning: 5 parts-7 parts of Herba Andrographis, 10 parts-12 parts, Folium Mori, 3 parts-5 parts of Radix Zanthoxylis, 3 parts-5 parts of Flos Loniceraes, 6 parts-8 parts of Radix Isatidis, 8 parts-10 parts of Herba Centellaes, 12 parts-14 parts, Folium Bambusae, Rhizoma Phragmitis 15-17 part.
2. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the weight portion proportioning of each raw material of Chinese medicine is: 6 parts of Herba Andrographis, 11 parts, Folium Mori, 4 parts of Radix Zanthoxylis, 4 parts of Flos Loniceraes, 7 parts of Radix Isatidis, 9 parts of Herba Centellaes, 13 parts, Folium Bambusae, 16 parts of Rhizoma Phragmitiss.
3. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the weight portion proportioning of each raw material of Chinese medicine is: 5 parts of Herba Andrographis, 10 parts, Folium Mori, 3 parts of Radix Zanthoxylis, 3 parts of Flos Loniceraes, 6 parts of Radix Isatidis, 8 parts of Herba Centellaes, 12 parts, Folium Bambusae, 15 parts of Rhizoma Phragmitiss.
4. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the weight portion proportioning of each raw material of Chinese medicine is: 7 parts of Herba Andrographis, 12 parts, Folium Mori, 5 parts of Radix Zanthoxylis, 5 parts of Flos Loniceraes, 8 parts of Radix Isatidis, 10 parts of Herba Centellaes, 14 parts, Folium Bambusae, 17 parts of Rhizoma Phragmitiss.
5. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, is characterized in that, the production method of described Chinese medicine preparation comprises following steps:
Step 1) takes by weight Herba Andrographis, Folium Mori, Radix Zanthoxyli, Flos Lonicerae, Radix Isatidis, Herba Centellae, Folium Bambusae, Rhizoma Phragmitis and pulverizes respectively, mixes;
Step 2) add the purified water of 8 times of weight, reflux and decoct 2 hours, a filters to get filtrate; In filtering residue, add the purified water of 4 times of weight, then the decoction 2 hours that refluxes, b filters to get filtrate; Filtrate a and b are mixed, carry out concentrating under reduced pressure, cumulative volume is reduced to original 1/4, be Chinese medicine water extracting liquid, for subsequent use;
Step 3) is diluted to recipe quantity 1g/mL by Chinese medicine water extracting liquid by purified water, gets product, and is placed in 4 DEG C of environment and saves backup.
6. the Chinese medicine preparation of control Naja respiratory system disease according to claim 1, it is characterized in that, the using method of described Chinese medicine preparation is: the finished product of having produced is applied to elapid feedstuff or joins in elapid normal drinking water evenly and mix, the preventive dose use that reduces by half.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410372139.9A CN104138541B (en) | 2014-07-31 | 2014-07-31 | Prevent and treat the Chinese medicine preparation and its production method of cobra respiratory disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410372139.9A CN104138541B (en) | 2014-07-31 | 2014-07-31 | Prevent and treat the Chinese medicine preparation and its production method of cobra respiratory disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104138541A true CN104138541A (en) | 2014-11-12 |
| CN104138541B CN104138541B (en) | 2017-07-11 |
Family
ID=51847991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410372139.9A Expired - Fee Related CN104138541B (en) | 2014-07-31 | 2014-07-31 | Prevent and treat the Chinese medicine preparation and its production method of cobra respiratory disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104138541B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104998111A (en) * | 2015-07-29 | 2015-10-28 | 邓克统 | Chinese traditional medicine preparation preventing and curing peacock respiratory system disease and production method thereof |
| CN107647117A (en) * | 2017-11-17 | 2018-02-02 | 广西雷村蛇场蛇业有限公司 | Special feed for cobras and preparation method thereof |
| CN107864925A (en) * | 2017-11-17 | 2018-04-03 | 广西雷村蛇场蛇业有限公司 | Breeding method for artificially bred meat cobras before marketing |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569181A (en) * | 2004-05-09 | 2005-01-26 | 王健伟 | Chinese medicine for preventing and treating air pollution harm and its preparation method |
| CN1840113A (en) * | 2006-01-23 | 2006-10-04 | 冯东 | Chinese medicinal preparation for treating viral influenza |
| CN102920946A (en) * | 2012-11-28 | 2013-02-13 | 蒋常德 | Preparation method of Chinese herbal medicinal active fermentation broth for preventing and treating porcine infectious diseases |
| CN103120267A (en) * | 2013-02-28 | 2013-05-29 | 灵山县园丰牧业有限公司 | Feed for lingshan patridge chicken |
-
2014
- 2014-07-31 CN CN201410372139.9A patent/CN104138541B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1569181A (en) * | 2004-05-09 | 2005-01-26 | 王健伟 | Chinese medicine for preventing and treating air pollution harm and its preparation method |
| CN1840113A (en) * | 2006-01-23 | 2006-10-04 | 冯东 | Chinese medicinal preparation for treating viral influenza |
| CN102920946A (en) * | 2012-11-28 | 2013-02-13 | 蒋常德 | Preparation method of Chinese herbal medicinal active fermentation broth for preventing and treating porcine infectious diseases |
| CN103120267A (en) * | 2013-02-28 | 2013-05-29 | 灵山县园丰牧业有限公司 | Feed for lingshan patridge chicken |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104998111A (en) * | 2015-07-29 | 2015-10-28 | 邓克统 | Chinese traditional medicine preparation preventing and curing peacock respiratory system disease and production method thereof |
| CN107647117A (en) * | 2017-11-17 | 2018-02-02 | 广西雷村蛇场蛇业有限公司 | Special feed for cobras and preparation method thereof |
| CN107864925A (en) * | 2017-11-17 | 2018-04-03 | 广西雷村蛇场蛇业有限公司 | Breeding method for artificially bred meat cobras before marketing |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104138541B (en) | 2017-07-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101176590B1 (en) | Herbal Composition for Removing Hangover and Beverage Containing the Same | |
| CN104351587A (en) | Cattle feed and preparation method thereof | |
| CN103405728B (en) | A kind of Chinese medicine composition for the treatment of climacteric syndrome and preparation method thereof | |
| CN104138541B (en) | Prevent and treat the Chinese medicine preparation and its production method of cobra respiratory disease | |
| CN103495072B (en) | Traditional Chinese medicine composition treating bronchiectasia disease and preparation method thereof | |
| CN104288234B (en) | The Chinese medicine preparation of preventing and treating sheep respiratory system disease and production method thereof | |
| KR101297918B1 (en) | Obesity treatment composition and method of manufacturing the obesity treatment composition | |
| CN104689283A (en) | Medicine for treatment of spleen insufficiency damp-aggregating type chloasma and preparation method thereof | |
| CN104587342A (en) | Medicinal liquor suitable for being drunk by patients with hyperthyroidism and preparation process thereof | |
| CN104547494A (en) | Traditional Chinese medicine composition medicinal liquor for treating hyperthyroidism and preparation process | |
| CN103860976B (en) | A kind of pharmaceutical composition for the treatment of infant's dermatitis | |
| CN103211988B (en) | Pharmaceutical composition for treating porcine infectious gastrointestinal inflammations | |
| KR20110112270A (en) | Manufacturing method of oral taking treatment for hair growth solution extracts from medical plants | |
| CN105920527A (en) | Medicine for treating stomach-yin deficiency type peptic ulcer and preparation method thereof | |
| CN105617121A (en) | Medicine for treating children stomatitis and preparation method of medicine | |
| CN105362993A (en) | Tincture for treating ichthyophthiriasis of parrotfish and preparation method of tincture for treating ichthyophthiriasis of parrotfish | |
| CN104814330A (en) | Dog food and preparation method thereof | |
| CN104800687A (en) | Traditional Chinese medicine preparation for treating infantile malnutrition and preparation method thereof | |
| CN104491652A (en) | Pharmaceutical composition for treating bovine pulmonary emphysema and preparation method of medicinal composition | |
| CN104873606A (en) | Traditional Chinese medicine external used agent for curing ulcerative gingivitis and preparation method thereof | |
| CN105106775A (en) | Traditional Chinese medicine preparation for treating puerperal constipation and preparation method thereof | |
| CN104998111A (en) | Chinese traditional medicine preparation preventing and curing peacock respiratory system disease and production method thereof | |
| CN104398902A (en) | Deficiency-cold type chronic bronchitis treating preparation for clearing away heat and dispersing lung and preparation method of preparation | |
| CN104288576A (en) | Traditional Chinese medicine preparation for treating respiratory system disease of Presbytis leucocephalus and production method of traditional Chinese medicine preparation | |
| CN104436003A (en) | Traditional Chinese medicine bath for treating urticaria of children and preparation method of traditional Chinese medicine bath |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170711 |