Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment acute mastitis, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment acute mastitis.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Carapax Eriocheir sinensis, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis, Pulvis concha Anodonta seu Cristaria, Cornu Cervi, Adeps sus domestica medicine to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat acute mastitis.Carapax Eriocheir sinensis is wherein selected to be because its nature and flavor acid, cold, poisonous, there is the function of removing blood stasis with potent drugs removing food stagnancy, control blood stasis and stagnate, hypochondriac pain, stomachache, acute mastitis, chilblain.Bulbus Fritillariae Cirrhosae is selected to be because its property bitter but sweet flavor, cool, enter lung meridian, have lung moistening eliminating stagnation, the function that antitussive reduces phlegm, control cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis.Select Fructus Trichosanthis to be because its nature and flavor sweetness and bitterness, cold, have lung moistening, reduce phlegm, eliminating stagnation, the function of laxation, controls phlegm-heat cough, the thoracic obstruction, blocked-up chest, and pulmonary fistula hemoptysis, quenches one's thirst, jaundice, constipation, carbuncle from the beginning of.Select Pulvis concha Anodonta seu Cristaria to be because its nature and flavor are salty, cold, nontoxic, enter lung, liver, stomach warp, have transforming phlegm and dispersing accumulations, the function of heat clearing and damp drying, controls cough due to fluid-retention, stomachache, vomiting, leucorrhea, carbuncle, eczema.Select Cornu Cervi to be because its nature and flavor are salty, temperature, enters liver, kidney channel, has promoting the circulation of blood, and detumescence, the function of kidney tonifying, controls sore swollen toxin, and blood stasis is had a pain, asthenia internal injury, pelvic bone pain.Select Adeps sus domestica to be that have tonify deficiency, moisturize, the function of removing toxic substances, controls internal organs dull and heavy, defecates unfavorable because its nature and flavor are sweet, cool, hot-temperedly to cough, chapped skin.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Carapax Eriocheir sinensis 15-25 gram of Bulbus Fritillariae Cirrhosae 12-20 gram of Fructus Trichosanthis 10-20 gram
Pulvis concha Anodonta seu Cristaria 10-18 gram of Cornu Cervi 12-20 gram of Adeps sus domestica 80-160 gram
Be preferably
Carapax Eriocheir sinensis 20 grams of Bulbus Fritillariae Cirrhosaes 15 grams of Fructus Trichosanthiss 15 grams
Pulvis concha Anodonta seu Cristaria 12 grams of Cornu Cervis 15 grams of Adeps sus domesticas 100 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Carapax Eriocheir sinensis: put by the Carapax Eriocheir sinensis after fragmentation and forge in medicine pot, is calcined to high heat and is popular in or crisp, takes out, cools, pulverize;
2, Bulbus Fritillariae Cirrhosae: pick decontamination, is soaked in water, and pulls out, and moistening peels off the heart, dries;
3, Fructus Trichosanthis: go handle to clean, puts in food steamer and steams to slightly soft, flatten, be cut into block;
4, Pulvis concha Anodonta seu Cristaria: get concha Anodonta seu Cristaria and clean, scrape off casting skin, be ground into fine powder;
5, Cornu Cervi: get a pound sheet and be ground into fine powder;
6, Adeps sus domestica: leaf fat is commonly called as leaf fat, twelfth month, refines it, and porcelain is collected.
Two, prepare
1, the Carapax Eriocheir sinensis of described weight, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis are ground to the powder altogether;
2, the Pulvis concha Anodonta seu Cristaria of described weight, harts horn carbon are added in ground Carapax Eriocheir sinensis, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis smalls mix thoroughly;
3, the Adeps sus domestica of described weight is entered pot heating to melt, then adds Carapax Eriocheir sinensis, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis, Cornu Cervi, Pulvis concha Anodonta seu Cristaria medicamental pulverata mix well, after cool ointment.
Medicine of the present invention has the function of heat clearing and damp drying, subduing swelling and detoxicating, is used for the treatment of acute mastitis instant effect, good effect.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, first exposes skin by rabbit abdominal part hair removing, then the ointment mixed up is spread upon rabbit abdominal part baring skin place, then twine with gauze and tie up, every day coating 2 times, continuous coating 5 days, observe every day administration reaction, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
Acute mastitis is mainly in the nursing women of not yet full moon in puerperal, with breast congestion and swelling pain for primary symptom.Lift red and swollen pain from the beginning of newborn portion, with heating, the General Symptoms such as aversion to cold, headache, with the passing of time makes pyosis rotten.Clinical characters is breast portion caking, swelling pain, and with whole body heating, after bursting, pus goes out stiff.
3, Therapeutic Method
Select above-mentioned ointment, be applied to affected part to patient, every day coating once, coating 10 days is a course for the treatment of, 3 courses for the treatment of of continuous coating.
4, efficacy assessment standard
Effective: acute mastitis symptom is fully recovered, recover normal.
Take a turn for the better: acute mastitis symptom alleviates, and progressively takes a turn for the better.
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy acute mastitis patient 100 example of the present invention, effective 87 examples of result, obvious effective rate is 87%, and take a turn for the better 7 examples, and improvement rate is 7%, and invalid 6 examples, total effective rate is 94%.