CN106728785A - It is a kind of to treat medicine of subcutaneous nodule and preparation method thereof - Google Patents
It is a kind of to treat medicine of subcutaneous nodule and preparation method thereof Download PDFInfo
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- CN106728785A CN106728785A CN201611149256.4A CN201611149256A CN106728785A CN 106728785 A CN106728785 A CN 106728785A CN 201611149256 A CN201611149256 A CN 201611149256A CN 106728785 A CN106728785 A CN 106728785A
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- Medicines Containing Plant Substances (AREA)
Abstract
Medicine of subcutaneous nodule and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by radix scrophulariae, root of Chinese trichosanthes, Radix Glycyrrhizae, halite, radix ampelopsis, Radix Angelicae Sinensis, marine alga, Fructus Aurantii, balloonflower root, fritillaria thunbergii, rheum officinale, peppermint, the capsule of weeping forsythia, extra large powder, medicine of the present invention has nourishing Yin and falling fire, relieving stagnant Qi row phlegm, replenishing and activating blood, heat-clearing dissipating bind, the function of wind-dispelling heat-dissipating, for treating subcutaneous nodule instant effect, good effect does not recur.
Description
Technical field
Medicine of subcutaneous nodule and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Background technology
Modern medicine thinks that subcutaneous nodule refers to the subcutaneous caking being swollen with such as core, is formed by damp phlegm stream is poly- more.Traditional Chinese medicine is then recognized
For this disease is mainly due to the dysfunction of the spleen in transport, phlegm wet resistance knot, caused by QI and blood being obstructed.At present, because Western medicine cannot effectively treat phlegm
Core, therefore there is great demand to the Chinese medicine of effectively treatment subcutaneous nodule in people, up to now, it has not been found that on this hair
The relevant report of bright medicine.
The content of the invention
The present inventor has been successfully found effective treatment finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science
The medicine of subcutaneous nodule, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment subcutaneous nodule.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is selection radix scrophulariae, root of Chinese trichosanthes, Radix Glycyrrhizae, halite, radix ampelopsis, Radix Angelicae Sinensis, marine alga, Fructus Aurantii, balloonflower root, Zhejiang shellfish
Mother, rheum officinale, peppermint, the capsule of weeping forsythia, Hai Fen, radix rehmanniae recen, selfheal, compound of glauber-salt and liquorice medicine are combined preparation, by these drug regimens
So that each efficacy of drugs produces synergy such that it is able to the effectively recurrence for the treatment of subcutaneous nodule.Wherein from radix scrophulariae because its property
Bitter, it is salty, it is cool, enter lung, kidney channel, there is enriching yin, fall fire, relieving restlessness, the function of removing toxic substances controls pyreticosis polydipsia, sends out spot, hectic fever due to yin labor heat, night
Sleep not peaceful, spontaneous sweating, Tianjin hinder constipation, hematemesis and epistaxis, abscess of throat, carbuncle swells, scrofula.From root of Chinese trichosanthes because its nature and flavor is sweet
Picric acid, it is cool, enter lung, stomach, have and promote the production of body fluid, to quench the thirst, fall fire is moisturized, apocenosis, the function of detumescence, and it is thirsty to control pyreticosis, quenches one's thirst, jaundice,
Dryness of the lung hemoptysis, carbuncle swells, hemorrhoid complicated by anal fistula.From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung channel, have and middle emergency, moistening lung, solution
Poison, the function of coordinating the drug actions of a prescription processs, deficiency of food weakness of the spleen and the stomach with controlling, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, and palpitaition shies carbuncle, raw
With controlling abscess of throat, peptic ulcer, ulcer sores, antidote poison and food poisoning.From halite because its is bitter in taste salty,
Cold, the thoughts of returning home, kidney, bladder warp have clearing heat and cooling blood, and the function of improving eyesight controls red eye, swell pain, spit blood, hematuria, swelling and aching of gum bleeding.Choosing
It is cool with radix ampelopsis because its nature and flavor bitter sweet is pungent, enter the heart, liver, the spleen channel, there is heat-clearing, to detoxify, dissipating bind, myogenic, the function of analgesic is controlled
Carbuncle swells, furunculosis, scrofula is scalded, a kind of malaria, bloody flux, intestines wind, anal fistula.From Radix Angelicae Sinensis because its nature and flavor sweet, acrid, warm, enter the heart, liver,
The spleen channel, there is replenishing and activating blood, and menstruction regulating and pain relieving, the function of moisturize laxation controls irregular menstruation, and Amenorrhea stomachache , Disorder lumps in the abdomen knot gathers, uterine bleeding, blood
Bitterly, dizziness, Impotence numbness, intestinal dryness is difficult just for deadhead, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.From marine alga because its property
Bitter is salty, trembles with fear, and enters lung, spleen, kidney channel, there is softening hard masses, and dissolving phlegm, Li Shui, the function of expelling the heat-evil controls scrofula, goiter and tumor, accumulation, oedema, pin
Gas, testiclar gall.From Fructus Aurantii because its nature and flavor toil, cool, enter lung, spleen, large intestine channel, there is relieving stagnant Qi, row phlegm, the work(of disperse accumulations
Can, it is stagnant to control chest diaphragm phlegm, the feeling of stuffiness in chest, coerces swollen, dyspepsia, and gas is vomitted inverse, weight, prolapse of the anus, the prolapse of uterus after diarrhea.From balloonflower root because
Its nature and flavor toil, puts down, and enters lung, stomach, there is out facilitaing lung gas, and the function of eliminating the phlegm apocenosis controls exogenous cough, and abscess of throat, lung carbuncle is told
Purulence, fullness in the chest and hypochondriac pain, dysentery stomachache.From fritillaria thunbergii because its is bitter in taste, it is slightly cold, return lung, the heart channel of Hang-Shaoyin have heat-clearing dissipating bind, resolving sputum
The function of cough-relieving, controls wind-heat affecting lung, and phlegm-fire cough, lung carbuncle, acute mastitis, scrofula, sore, ambition is gloomy.From rheum officinale because its
It is bitter in taste, cold, enter stomach, large intestine, liver footpath, there is the poison that purges heat, break stagnant, the function of row hemostasis controls real heat constipation, and delirious speech is gone mad, food
Product feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menopause Bi , lumps in the chest and abdomen, when the hot epidemic disease of row, sudden and violent swelling ophthalmalgia spits blood, bleeding from five sense organs or subcutaneous tissue, yang jaundice,
Oedema, stranguria with turbid discharge is urinated red, large carbuncle pyogenic infections, furunculosis, burn.It is cool from peppermint because its nature and flavor is pungent, enter lung, Liver Channel, have thin
Wind, radiating, wards off dirty, and the function of removing toxic substances controls affection of exogenous wind-heat, headache, hot eyes, abscess of throat, food stagnation inflatable, aphtha, toothache, sore
Scabies, urticaria.It is cool from the capsule of weeping forsythia because its is bitter in taste, enter the heart, liver, gallbladder channel, there is heat-clearing, to detoxify, dissipating bind, the function of detumescence is controlled
Warm, erysipelas, macula, large carbuncle pyogenic infections, scrofula, urine leaching closes.From extra large powder because its property sweet-salty, trembles with fear, enter lung, Liver Channel,
There is clearing heat and nourishing yin, the function of softening hard masses dissolving phlegm is controlled the dryness of the lung and breathed with cough, goiter and tumor, scrofula.From radix rehmanniae recen because its nature and flavor is sweet, tremble with fear, return
The heart, liver and kidney channel, there is clearing heat and cooling blood, and yin-nourishing, the function of promoting the production of body fluid controls pyreticosis polydipsia, and yin asthenia generating intrinsic heat, hectic fever due to yin labor is hot, Heat Diabetes,
Spit blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.From selfheal because its nature and flavor toil, tremble with fear, enter liver, gallbladder channel have a clearing liver, the function of dissipating bind,
Scrofula is controlled, goiter and tumor, acute mastitis, breast cancer, mesh pearl nyctalgia, photophobia is shed tears, vertigo, facial paralysis, arthralgia and myalgia, pulmonary tuberculosis, it is anxious
Property icteric catarrhal jaundice, metrorrhagia, under band.From the compound of glauber-salt and liquorice because its nature and flavor is pungent salty, tremble with fear, enter stomach, large intestine channel, have and rush down
Heat, moisturizes, the function of softening hard masses, controls real heat and stagnates, and suffers from constipation, red eye, swell pain, pharynx swelling aphtha, swollen ulcer drug.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy
All there is preferable curative effect in the range of amount：
200-300 grams of radix scrophulariae, 45-55 grams of root of Chinese trichosanthes, 45-55 grams of Radix Glycyrrhizae, 200-300 grams of halite, 45-55 grams of radix ampelopsis, Radix Angelicae Sinensis
45-55 grams, 45-55 grams of marine alga, 45-55 grams of Fructus Aurantii, 45-55 grams of balloonflower root, 45-55 grams of fritillaria thunbergii, 45-55 grams of rheum officinale, peppermint 45-
55 grams, 45-55 grams of the capsule of weeping forsythia, 45-55 grams of extra large powder, 45-55 grams of radix rehmanniae recen, 350-450 grams of selfheal, 45-55 grams of the compound of glauber-salt and liquorice.
Preferably：
250 grams of radix scrophulariae, 50 grams of root of Chinese trichosanthes, 50 grams of Radix Glycyrrhizae, 250 grams of halite, 50 grams of radix ampelopsis, 50 grams of Radix Angelicae Sinensis, 50 grams of marine alga, Fructus Aurantii
50 grams, 50 grams of balloonflower root, 50 grams of fritillaria thunbergii, 50 grams of rheum officinale, 50 grams of peppermint, 50 grams of the capsule of weeping forsythia, 50 grams of extra large powder, 50 grams of radix rehmanniae recen, the summer is withered
400 grams of grass, 50 grams of the compound of glauber-salt and liquorice.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, radix scrophulariae：Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried；
2nd, root of Chinese trichosanthes：Impurity is picked, size block is separate, pulled out with bubble to sixty percent thoroughly, vexed profit is uniform to inside and outside humidity, section,
Dry, or wash, pull out, shine to extremely dry, be pounded fritter；
3rd, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；
4th, halite：Crude drug is taken, impurity is removed；
5th, radix ampelopsis：Spring, autumn excavation, remove stem and thin fibrous root, clean, and many rip cuttings are dried into after two valves, pintongs or inclined tab；
6th, Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
7th, marine alga：Impurity is picked, is slightly floated with water, slightly dried in the air, segment is dried；
8th, Fructus Aurantii：Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried；
9th, balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；
10th, fritillaria thunbergii：Impurity is removed, size stepping is cleaned, run through, and cuts sheet, is dried, and chip is removed in street, or is smashed；
11st, rheum officinale：Net impurity is picked, size stepping stews to moisten to inside and outside humidity uniformly, cuts into slices or be cut into small pieces, dries；
12nd, peppermint：Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is then sprayed into clear water, run through rear segment, solarization
It is dry, then with leaf and even；
13rd, the capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；
14th, Hai Fen：Between the 2-3 months and 9-10 month sea hare egg-laying seasons, in the attachment such as marine insertion bamboo pole or input stone, make spawning
Yu Shang, dries after collecting；
15th, radix rehmanniae recen：Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip；
16th, selfheal：Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out；
17th, the compound of glauber-salt and liquorice：Original is used as medicine.
2nd, prepare
1st, the radix scrophulariae that will cook, root of Chinese trichosanthes, Radix Glycyrrhizae, halite, radix ampelopsis, Radix Angelicae Sinensis, marine alga, Fructus Aurantii, balloonflower root, fritillaria thunbergii, rheum officinale,
Peppermint, the capsule of weeping forsythia, Hai Fen, radix rehmanniae recen mixing and stirring, grind as fine powder crosses 200 mesh dusting covers；
2nd, by selfheal decoct soup, the compound of glauber-salt and liquorice is dissolved in decoction and is stirred evenly；
3rd, radix scrophulariae, root of Chinese trichosanthes, Radix Glycyrrhizae, halite, radix ampelopsis, Radix Angelicae Sinensis, marine alga, Fructus Aurantii, balloonflower root, fritillaria thunbergii, rheum officinale, peppermint, company are taken
Stick up, Hai Fen, radix rehmanniae recen fine powder, the mixing system in selfheal and compound of glauber-salt and liquorice decoction that is put into sticks together, then rubbing pill, per 5 grams of ball.
Medicine of the present invention has nourishing Yin and falling fire, and relieving stagnant Qi row phlegm, replenishing and activating blood, heat-clearing dissipating bind, the function of wind-dispelling heat-dissipating is used for
Treat subcutaneous nodule instant effect, good effect, do not recur.
Radix scrophulariae has nourishing Yin and falling fire in prescription, and the function of relieving restlessness removing toxic substances is monarch drug in a prescription, and Fructus Aurantii relieving stagnant Qi row phlegm, Chinese angelica blood supplementing are invigorated blood circulation,
Both moisturize laxations are ministerial drug；Three taste medicines play nourishing Yin and falling fire, relieving restlessness removing toxic substances, relieving stagnant Qi row phlegm, replenishing and activating blood, moisturize laxation jointly
Effect, comprehensively, and with nourishing Yin and falling fire, relieving stagnant Qi row phlegm can effect a permanent cure based on replenishing and activating blood treatment subcutaneous nodule effect, and fritillaria thunbergii heat-clearing dissipates
Knot, preventing phlegm from forming and stopping coughing is adjutant, and peppermint wind-dispelling heat-dissipating wards off dirty removing toxic substances to make medicine, and all medicines are to take stopgap measures with being left, by said medicine group
Close, be allowed to efficacy of drugs and produce synergy such that it is able to the effectively recurrence for the treatment of subcutaneous nodule.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these experiments include medicine of the present invention
Animal toxicity test and clinical observation on the therapeutic effect experiment.
The animal toxicity test of [test example 1] medicine of the present invention
West Germany rabbit 30 is taken, male and female dual-purpose, body weight 2.0-2.5kg is divided into two groups, and one of which is overdose, another group for just
Constant, takes pill overdose group 0.25g/kg, normal amount group 0.15g/kg, is administered using dilution administration by gavage, twice a day, even
Continuous to take 7 days, as a result observation administration reaction shows that rabbit activity, diet are normal, and medicine is without bad toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept out-patient totally 25 for medical treatment.
2nd, diagnostic criteria
Subcutaneous nodule clinical manifestation has：Neck, item, lower jaw part or four limbs, lump under shoulder butt.
3rd, treatment method
Daily respectively to take 3 balls sooner or later, 7 days courses for the treatment of take medicine continuously 3 courses for the treatment of.
4th, efficacy assessment standard
It is effective：Subcutaneous nodule related symptoms disappear, and constitution recovers normal, recovery from illness；
Take a turn for the better：Neck, item, lower jaw part or four limbs, caking fades away under shoulder butt；
It is invalid：Improvement standard person is not reached.
5th, treatment results（See the table below）：
In above-mentioned treatment, with drug therapy subcutaneous nodule patient 25 of the present invention, as a result effective 20, take a turn for the better 4, obvious effective rate is
80%, improvement rate is that 16% total effective rate is 96%.
Claims (3)
1. a kind of medicine for treating subcutaneous nodule, it is characterised in that：It is made up of the bulk drug in following weight range：
200-300 grams of radix scrophulariae, 45-55 grams of root of Chinese trichosanthes, 45-55 grams of Radix Glycyrrhizae, 200-300 grams of halite, 45-55 grams of radix ampelopsis, Radix Angelicae Sinensis
45-55 grams, 45-55 grams of marine alga, 45-55 grams of Fructus Aurantii, 45-55 grams of balloonflower root, 45-55 grams of fritillaria thunbergii, 45-55 grams of rheum officinale, peppermint 45-
55 grams, 45-55 grams of the capsule of weeping forsythia, 45-55 grams of extra large powder, 45-55 grams of radix rehmanniae recen, 350-450 grams of selfheal, 45-55 grams of the compound of glauber-salt and liquorice.
2. medicine according to claim 1, wherein the consumption of each bulk drug is：
250 grams of radix scrophulariae, 50 grams of root of Chinese trichosanthes, 50 grams of Radix Glycyrrhizae, 250 grams of halite, 50 grams of radix ampelopsis, 50 grams of Radix Angelicae Sinensis, 50 grams of marine alga, Fructus Aurantii
50 grams, 50 grams of balloonflower root, 50 grams of fritillaria thunbergii, 50 grams of rheum officinale, 50 grams of peppermint, 50 grams of the capsule of weeping forsythia, 50 grams of extra large powder, 50 grams of radix rehmanniae recen, the summer is withered
400 grams of grass, 50 grams of the compound of glauber-salt and liquorice.
3. the preparation method of medicine according to claim 1 or claim 2, it is characterised in that：It comprises the following steps：
（One）Get the raw materials ready
（1）Radix scrophulariae：Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried；
（2）Root of Chinese trichosanthes：Impurity is picked, size block is separate, pulled out with bubble to sixty percent thoroughly, vexed profit is uniform to inside and outside humidity, cuts
Piece, dries, or washes, and pulls out, shines to extremely dry, is pounded fritter；
（3）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；
（4）Halite：Crude drug is taken, impurity is removed；
（5）Radix ampelopsis：Spring, autumn excavation, remove stem and thin fibrous root, clean, and many rip cuttings are dried into after two valves, pintongs or inclined tab；
（6）Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
（7）Marine alga：Impurity is picked, is slightly floated with water, slightly dried in the air, segment is dried；
（8）Fructus Aurantii：Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried；
（9）Balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；
（10）Fritillaria thunbergii：Impurity is removed, size stepping is cleaned, run through, and cuts sheet, is dried, and chip is removed in street, or is smashed；
（11）Rheum officinale：Net impurity is picked, size stepping stews to moisten to inside and outside humidity uniformly, cuts into slices or be cut into small pieces, dries；
（12）Peppermint：Pick net impurity, remove undesirable root, first by leaf tremble it is lower separately put, stem is then sprayed into clear water, run through rear segment, solarization
It is dry, then with leaf and even；
（13）The capsule of weeping forsythia：Net impurity is picked, stranding is opened, except discarding stalk；
（14）Hai Fen：Between the 2-3 months and 9-10 month sea hare egg-laying seasons, in the attachment such as marine insertion bamboo pole or input stone, make product
Ovum is dried in upper after collecting；
（15）Radix rehmanniae recen：Crude drug is taken, impurity is removed, cleaned, slightly moistened, cut sheet, dried, weed out chip；
（16）Selfheal：Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out；
（17）The compound of glauber-salt and liquorice：Original is used as medicine；
（Two）Prepare
（1）It is the radix scrophulariae that will cook, root of Chinese trichosanthes, Radix Glycyrrhizae, halite, radix ampelopsis, Radix Angelicae Sinensis, marine alga, Fructus Aurantii, balloonflower root, fritillaria thunbergii, big
Huang, peppermint, the capsule of weeping forsythia, Hai Fen, radix rehmanniae recen mixing and stirring, grind as fine powder crosses 200 mesh dusting covers；
（2）By selfheal decoct soup, the compound of glauber-salt and liquorice is dissolved in decoction and is stirred evenly；
（3）Take radix scrophulariae, root of Chinese trichosanthes, Radix Glycyrrhizae, halite, radix ampelopsis, Radix Angelicae Sinensis, marine alga, Fructus Aurantii, balloonflower root, fritillaria thunbergii, rheum officinale, peppermint, company
Stick up, Hai Fen, radix rehmanniae recen fine powder, the mixing system in selfheal and compound of glauber-salt and liquorice decoction that is put into sticks together, then rubbing pill, per 5 grams of ball.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109893593A (en) * | 2017-12-07 | 2019-06-18 | 天津中新药业集团股份有限公司隆顺榕制药厂 | A kind of Chinese medicine composition and preparation method thereof for treating tumour |
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2016
- 2016-12-14 CN CN201611149256.4A patent/CN106728785A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
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| 陈东银等: "《汤头歌诀》", 31 July 2015, 金盾出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109893593A (en) * | 2017-12-07 | 2019-06-18 | 天津中新药业集团股份有限公司隆顺榕制药厂 | A kind of Chinese medicine composition and preparation method thereof for treating tumour |
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