Summary of the invention
The inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, has finally found the medicine of effective treatment acute mastitis, thereby has completed the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment acute mastitis.
Another object of the present invention has just been to provide the preparation method of this Chinese medicine composition.
Medicine of the present invention is to select Carapax Eriocheir sinensis, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis, Pulvis concha Anodonta seu Cristaria, Cornu Cervi, Adeps sus domestica medicine to combine preparation, makes each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat acute mastitis.Wherein select Carapax Eriocheir sinensis to be because its nature and flavor acid is cold, poisonous, have the function of removing blood stasis with potent drugs removing food stagnancy, control blood stasis stagnant, hypochondriac pain, stomachache, acute mastitis, chilblain.Select Bulbus Fritillariae Cirrhosae to be because its property bitter but sweet flavor is cool, enter lung meridian, have lung moistening eliminating stagnation, the function that antitussive reduces phlegm, controls cough due to consumptive disease, the spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, scrofula, sore throat, acute mastitis.Selecting Fructus Trichosanthis is because its nature and flavor sweetness and bitterness, cold, has lung moistening, reduce phlegm, eliminating stagnation, the function of laxation, controls phlegm-heat cough, the thoracic obstruction, blocked-up chest, pulmonary fistula hemoptysis, quenches one's thirst, jaundice, constipation, carbuncle from the beginning of.Select Pulvis concha Anodonta seu Cristaria to be because its nature and flavor are salty, cold, nontoxic, enter lung, liver, stomach warp, there is transforming phlegm and dispersing accumulations, the function of heat clearing and damp drying, controls cough due to fluid-retention, stomachache, vomiting, leucorrhea, carbuncle, eczema.Select Cornu Cervi to be because its nature and flavor are salty, temperature, enters liver, kidney channel, has promoting the circulation of blood, detumescence, and the function of kidney tonifying, controls sore swollen toxin, and blood stasis is had a pain, asthenia internal injury, pelvic bone pain.Select Adeps sus domestica to be because its nature and flavor are sweet, cool, have tonify deficiency, moisturize, the function of removing toxic substances, controls internal organs dull and heavy, defecate unfavorable, and hot-tempered coughing, chapped skin.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Carapax Eriocheir sinensis 15-25 gram of Bulbus Fritillariae Cirrhosae 12-20 gram of Fructus Trichosanthis 10-20 gram
Pulvis concha Anodonta seu Cristaria 10-18 gram of Cornu Cervi 12-20 gram of Adeps sus domestica 80-160 gram
Be preferably
15 grams of 15 grams of Fructus Trichosanthiss of 20 grams of Bulbus Fritillariae Cirrhosaes of Carapax Eriocheir sinensis
100 grams of 15 grams of Adeps sus domesticas of 12 grams of Cornu Cervis of Pulvis concha Anodonta seu Cristaria
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Carapax Eriocheir sinensis: the Carapax Eriocheir sinensis after fragmentation is put and forged in medicine pot, be calcined to high heat and be popular in or crisp, take out, cool, pulverize;
2, Bulbus Fritillariae Cirrhosae: choose decontamination, be soaked in water, pull out, moistening, peels off the heart, dries;
3, Fructus Trichosanthis: go handle to clean, put in food steamer and steam to slightly soft, flatten, be cut into piece;
4, Pulvis concha Anodonta seu Cristaria: get concha Anodonta seu Cristaria and clean, scrape off casting skin, be ground into fine powder;
5, Cornu Cervi: get a pound sheet and be ground into fine powder;
6, Adeps sus domestica: leaf fat is commonly called as leaf fat, twelfth month, is refined it, porcelain collection.
Two, preparation
1, the Carapax Eriocheir sinensis of described weight, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis are ground to the powder altogether;
2, the Pulvis concha Anodonta seu Cristaria of described weight, harts horn carbon are added in ground Carapax Eriocheir sinensis, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis smalls and mixed thoroughly;
3, the Adeps sus domestica of described weight is entered to pot heating and melts, then add Carapax Eriocheir sinensis, Bulbus Fritillariae Cirrhosae, Fructus Trichosanthis, Cornu Cervi, Pulvis concha Anodonta seu Cristaria medicamental pulverata to mix well, after cool ointment.
Medicine of the present invention has the function of heat clearing and damp drying, subduing swelling and detoxicating, is used for the treatment of acute mastitis instant effect, good effect.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get 30 of West Germany rabbits, male and female dual-purpose, body weight 2.0-2.5kg, first exposes skin by rabbit abdominal part hair removing, then the ointment mixing up is spread upon to rabbit abdominal part baring skin place, then with gauze, twine and tie up, every day, coating was 2 times, and coating is 5 days continuously, observed administration reaction every day, result shows that rabbit is movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 100 examples for medical treatment.
2, diagnostic criteria
Acute mastitis is mainly in the nursing women of full moon not yet in puerperal, take breast congestion and swelling pain as primary symptom.From the beginning of newborn portion, lift red and swollen pain, with heating, the General Symptomies such as aversion to cold, headache, with the passing of time make pyosis rotten.Clinical characters is breast portion caking, swelling pain, and with whole body heating, after bursting, pus goes out stiff.
3, Therapeutic Method
Select above-mentioned ointment, to patient, be applied to affected part, every day coating once, coating 10 days is a course for the treatment of, continuously 3 courses for the treatment of of coating.
4, efficacy assessment standard
Effective: the recovery from illness of acute mastitis symptom, recovers normal.
Take a turn for the better: acute mastitis symptom alleviates, progressively take a turn for the better.
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy acute mastitis patient of the present invention 100 examples, effective 87 examples of result, obvious effective rate is 87%, 7 examples that take a turn for the better, and improvement rate is 7%, invalid 6 examples, total effective rate is 94%.