CN103341151B - Traditional Chinese medicine for treating chronic bronchitis - Google Patents
Traditional Chinese medicine for treating chronic bronchitis Download PDFInfo
- Publication number
- CN103341151B CN103341151B CN201310326410.0A CN201310326410A CN103341151B CN 103341151 B CN103341151 B CN 103341151B CN 201310326410 A CN201310326410 A CN 201310326410A CN 103341151 B CN103341151 B CN 103341151B
- Authority
- CN
- China
- Prior art keywords
- weight portion
- chinese medicine
- semen
- decoct
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 68
- 206010006451 Bronchitis Diseases 0.000 title claims abstract description 21
- 206010006458 Bronchitis chronic Diseases 0.000 title claims abstract description 21
- 208000007451 Chronic Bronchitis Diseases 0.000 title claims abstract description 21
- 239000009636 Huang Qi Substances 0.000 claims abstract description 16
- 241001412171 Rubus corchorifolius Species 0.000 claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 48
- 210000000582 Semen Anatomy 0.000 claims description 44
- 241000628997 Flos Species 0.000 claims description 32
- 239000000843 powder Substances 0.000 claims description 24
- 229940079593 drugs Drugs 0.000 claims description 22
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 20
- 239000002244 precipitate Substances 0.000 claims description 20
- 239000008187 granular material Substances 0.000 claims description 19
- 150000001875 compounds Chemical class 0.000 claims description 15
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 15
- 239000006188 syrup Substances 0.000 claims description 14
- 235000020357 syrup Nutrition 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 12
- CZMRCDWAGMRECN-UGDNZRGBSA-N D-sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 10
- 229960004793 Sucrose Drugs 0.000 claims description 10
- 239000002253 acid Substances 0.000 claims description 10
- 239000000706 filtrate Substances 0.000 claims description 10
- 238000001914 filtration Methods 0.000 claims description 10
- 239000012567 medical material Substances 0.000 claims description 10
- 239000006228 supernatant Substances 0.000 claims description 10
- 239000002552 dosage form Substances 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- WXMKPNITSTVMEF-UHFFFAOYSA-M Sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 6
- CZMRCDWAGMRECN-GDQSFJPYSA-N Sucrose Natural products O([C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1)[C@@]1(CO)[C@H](O)[C@@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-GDQSFJPYSA-N 0.000 claims description 6
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 6
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 235000010234 sodium benzoate Nutrition 0.000 claims description 6
- 239000004299 sodium benzoate Substances 0.000 claims description 6
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 6
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 6
- 230000001954 sterilising Effects 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 239000005720 sucrose Substances 0.000 claims description 6
- 239000007779 soft material Substances 0.000 claims description 4
- 239000003390 Chinese drug Substances 0.000 claims 1
- 201000010099 disease Diseases 0.000 abstract description 29
- 230000000694 effects Effects 0.000 abstract description 23
- 231100000957 no side effect Toxicity 0.000 abstract description 3
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 235000017965 Asarum canadense Nutrition 0.000 abstract 1
- 235000006463 Brassica alba Nutrition 0.000 abstract 1
- 244000140786 Brassica hirta Species 0.000 abstract 1
- 235000011371 Brassica hirta Nutrition 0.000 abstract 1
- 240000004499 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 240000003472 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 240000009301 Coix lacryma-jobi Species 0.000 abstract 1
- 235000000385 Costus speciosus Nutrition 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 240000004229 Crocus sativus Species 0.000 abstract 1
- 241000132446 Inula Species 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 241000972673 Phellodendron amurense Species 0.000 abstract 1
- 240000005204 Prunus armeniaca Species 0.000 abstract 1
- 235000009827 Prunus armeniaca Nutrition 0.000 abstract 1
- 240000007742 Raphanus sativus Species 0.000 abstract 1
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 abstract 1
- 235000004224 Typha angustifolia Nutrition 0.000 abstract 1
- 235000005391 Typha capensis Nutrition 0.000 abstract 1
- 235000019026 Typha domingensis Nutrition 0.000 abstract 1
- 240000000260 Typha latifolia Species 0.000 abstract 1
- 235000005324 Typha latifolia Nutrition 0.000 abstract 1
- 241000606265 Valeriana jatamansi Species 0.000 abstract 1
- 240000007329 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 235000014687 Zingiber zerumbet Nutrition 0.000 abstract 1
- 235000006545 Ziziphus mauritiana Nutrition 0.000 abstract 1
- 244000126002 Ziziphus vulgaris Species 0.000 abstract 1
- 235000008529 Ziziphus vulgaris Nutrition 0.000 abstract 1
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 1
- 235000015386 bitter orange Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- 231100000956 nontoxicity Toxicity 0.000 abstract 1
- 235000013974 saffron Nutrition 0.000 abstract 1
- 239000004248 saffron Substances 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 description 33
- 210000000952 Spleen Anatomy 0.000 description 32
- 210000004072 Lung Anatomy 0.000 description 31
- 210000004369 Blood Anatomy 0.000 description 23
- 239000008280 blood Substances 0.000 description 23
- 210000000214 Mouth Anatomy 0.000 description 21
- 210000003734 Kidney Anatomy 0.000 description 17
- 206010062717 Increased upper airway secretion Diseases 0.000 description 15
- 208000002193 Pain Diseases 0.000 description 15
- 210000002784 Stomach Anatomy 0.000 description 13
- 230000001717 pathogenic Effects 0.000 description 13
- 235000009508 confectionery Nutrition 0.000 description 12
- 230000003419 expectorant Effects 0.000 description 12
- 239000003172 expectorant agent Substances 0.000 description 12
- 238000010792 warming Methods 0.000 description 11
- 206010036790 Productive cough Diseases 0.000 description 10
- 208000006673 Asthma Diseases 0.000 description 9
- 206010016807 Fluid retention Diseases 0.000 description 9
- 230000001737 promoting Effects 0.000 description 9
- 210000002216 Heart Anatomy 0.000 description 7
- 201000010874 syndrome Diseases 0.000 description 7
- 206010012735 Diarrhoea Diseases 0.000 description 6
- 210000004185 Liver Anatomy 0.000 description 6
- 231100000614 Poison Toxicity 0.000 description 6
- 206010047924 Wheezing Diseases 0.000 description 6
- 210000000038 chest Anatomy 0.000 description 6
- 235000019525 fullness Nutrition 0.000 description 6
- 230000014759 maintenance of location Effects 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 208000006820 Arthralgia Diseases 0.000 description 5
- 208000001848 Dysentery Diseases 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 235000013305 food Nutrition 0.000 description 5
- 230000001047 pyretic Effects 0.000 description 5
- 230000029058 respiratory gaseous exchange Effects 0.000 description 5
- 206010007247 Carbuncle Diseases 0.000 description 4
- 206010010774 Constipation Diseases 0.000 description 4
- 241000668709 Dipterocarpus costatus Species 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 4
- 206010013975 Dyspnoeas Diseases 0.000 description 4
- 208000008454 Hyperhidrosis Diseases 0.000 description 4
- 206010068319 Oropharyngeal pain Diseases 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 4
- 230000004087 circulation Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 244000052769 pathogens Species 0.000 description 4
- 230000002035 prolonged Effects 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 230000002522 swelling Effects 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 231100000419 toxicity Toxicity 0.000 description 4
- 230000001988 toxicity Effects 0.000 description 4
- 206010001928 Amenorrhoea Diseases 0.000 description 3
- 208000002894 Beriberi Diseases 0.000 description 3
- 206010059866 Drug resistance Diseases 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 210000003802 Sputum Anatomy 0.000 description 3
- 210000003932 Urinary Bladder Anatomy 0.000 description 3
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 3
- 201000000736 amenorrhea Diseases 0.000 description 3
- 231100000540 amenorrhea Toxicity 0.000 description 3
- 230000000844 anti-bacterial Effects 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000003203 everyday Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 210000002429 large intestine Anatomy 0.000 description 3
- 239000000314 lubricant Substances 0.000 description 3
- 210000004877 mucosa Anatomy 0.000 description 3
- 230000000414 obstructive Effects 0.000 description 3
- 230000008506 pathogenesis Effects 0.000 description 3
- 230000000306 recurrent Effects 0.000 description 3
- 230000002040 relaxant effect Effects 0.000 description 3
- 230000001225 therapeutic Effects 0.000 description 3
- 210000001015 Abdomen Anatomy 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 208000006111 Contracture Diseases 0.000 description 2
- 206010061428 Decreased appetite Diseases 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 208000005679 Eczema Diseases 0.000 description 2
- 206010016286 Febrile disease Diseases 0.000 description 2
- 206010018836 Haematochezia Diseases 0.000 description 2
- 206010061245 Internal injury Diseases 0.000 description 2
- 210000000936 Intestines Anatomy 0.000 description 2
- 206010025482 Malaise Diseases 0.000 description 2
- 206010027514 Metrorrhagia Diseases 0.000 description 2
- 206010062575 Muscle contracture Diseases 0.000 description 2
- 210000003205 Muscles Anatomy 0.000 description 2
- 241000208125 Nicotiana Species 0.000 description 2
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 206010072736 Rheumatic disease Diseases 0.000 description 2
- 241000220261 Sinapis Species 0.000 description 2
- 206010040943 Skin ulcer Diseases 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 230000002804 anti-anaphylactic Effects 0.000 description 2
- 230000003110 anti-inflammatory Effects 0.000 description 2
- 230000003115 biocidal Effects 0.000 description 2
- 201000004624 dermatitis Diseases 0.000 description 2
- 201000009910 diseases by infectious agent Diseases 0.000 description 2
- 231100001003 eczema Toxicity 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 230000000622 irritating Effects 0.000 description 2
- 230000002147 killing Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000006011 modification reaction Methods 0.000 description 2
- 231100000862 numbness Toxicity 0.000 description 2
- 210000000056 organs Anatomy 0.000 description 2
- 244000045947 parasites Species 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000000552 rheumatic Effects 0.000 description 2
- 231100000019 skin ulcer Toxicity 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000001629 suppression Effects 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 206010069351 Acute lung injury Diseases 0.000 description 1
- 229960003556 Aminophylline Drugs 0.000 description 1
- FQPFAHBPWDRTLU-UHFFFAOYSA-N Aminophylline Chemical compound NCCN.O=C1N(C)C(=O)N(C)C2=C1NC=N2.O=C1N(C)C(=O)N(C)C2=C1NC=N2 FQPFAHBPWDRTLU-UHFFFAOYSA-N 0.000 description 1
- 208000002399 Aphthous Stomatitis Diseases 0.000 description 1
- 210000001367 Arteries Anatomy 0.000 description 1
- 241000271566 Aves Species 0.000 description 1
- 229950003588 Axetil Drugs 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 210000000481 Breast Anatomy 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 208000009079 Bronchial Spasm Diseases 0.000 description 1
- 206010006482 Bronchospasm Diseases 0.000 description 1
- 206010007554 Cardiac failure Diseases 0.000 description 1
- 210000003756 Cervix Mucus Anatomy 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 201000006306 Cor pulmonale Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 208000002173 Dizziness Diseases 0.000 description 1
- 206010013990 Dysuria Diseases 0.000 description 1
- 206010014561 Emphysema Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 208000001780 Epistaxis Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 210000003414 Extremities Anatomy 0.000 description 1
- 206010016717 Fistula Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010018987 Haemorrhage Diseases 0.000 description 1
- 206010019233 Headache Diseases 0.000 description 1
- 206010019280 Heart failure Diseases 0.000 description 1
- 229940000351 Hemocyte Drugs 0.000 description 1
- 210000003677 Hemocytes Anatomy 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 210000001624 Hip Anatomy 0.000 description 1
- 206010020710 Hyperphagia Diseases 0.000 description 1
- 206010020718 Hyperplasia Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 210000003026 Hypopharynx Anatomy 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 206010022114 Injury Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 208000004396 Mastitis Diseases 0.000 description 1
- 206010027327 Menstrual disease Diseases 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 206010029410 Night sweats Diseases 0.000 description 1
- 210000003516 Pericardium Anatomy 0.000 description 1
- 210000003800 Pharynx Anatomy 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 208000008425 Protein Deficiency Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 206010061920 Psychotic disease Diseases 0.000 description 1
- 208000004186 Pulmonary Heart Disease Diseases 0.000 description 1
- 210000004915 Pus Anatomy 0.000 description 1
- 210000001533 Respiratory Mucosa Anatomy 0.000 description 1
- 241000282806 Rhinoceros Species 0.000 description 1
- 210000003296 Saliva Anatomy 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 229920001800 Shellac Polymers 0.000 description 1
- 210000003491 Skin Anatomy 0.000 description 1
- 206010040872 Skin infection Diseases 0.000 description 1
- 206010067868 Skin mass Diseases 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 206010042170 Strangury Diseases 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 241000270666 Testudines Species 0.000 description 1
- 229960000278 Theophylline Drugs 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 208000004371 Toothache Diseases 0.000 description 1
- 231100000765 Toxin Toxicity 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 206010044334 Trance Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 206010046901 Vaginal discharge Diseases 0.000 description 1
- 210000003462 Veins Anatomy 0.000 description 1
- 206010052769 Vertigos Diseases 0.000 description 1
- 208000009257 Visceral Prolapse Diseases 0.000 description 1
- 206010063840 Visceroptosis Diseases 0.000 description 1
- 230000003187 abdominal Effects 0.000 description 1
- 230000003213 activating Effects 0.000 description 1
- 230000001396 anti-anti-diuretic Effects 0.000 description 1
- 230000001166 anti-perspirant Effects 0.000 description 1
- 230000001754 anti-pyretic Effects 0.000 description 1
- 230000000840 anti-viral Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 230000001174 ascending Effects 0.000 description 1
- 230000000721 bacterilogical Effects 0.000 description 1
- 230000000740 bleeding Effects 0.000 description 1
- 231100000319 bleeding Toxicity 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000001413 cellular Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001684 chronic Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 231100000895 deafness Toxicity 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000000994 depressed Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000008286 diarrhea Diseases 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 230000001882 diuretic Effects 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000002708 enhancing Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000002919 epithelial cells Anatomy 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002949 hemolytic Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000001771 impaired Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000001524 infective Effects 0.000 description 1
- 230000002757 inflammatory Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- 230000003902 lesions Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 201000003453 lung abscess Diseases 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 201000005505 measles Diseases 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 230000003000 nontoxic Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000000474 nursing Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000000242 pagocytic Effects 0.000 description 1
- 230000025627 positive regulation of urine volume Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002685 pulmonary Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 230000000171 quenching Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001105 regulatory Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 230000000241 respiratory Effects 0.000 description 1
- 230000000630 rising Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000004208 shellac Substances 0.000 description 1
- 229940113147 shellac Drugs 0.000 description 1
- 235000013874 shellac Nutrition 0.000 description 1
- 231100000486 side effect Toxicity 0.000 description 1
- 201000009890 sinusitis Diseases 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000003393 splenic Effects 0.000 description 1
- 230000002269 spontaneous Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 210000001519 tissues Anatomy 0.000 description 1
- 230000002588 toxic Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 230000001131 transforming Effects 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 239000008434 yi-zhi Substances 0.000 description 1
Abstract
The invention provides a traditional Chinese medicine for treating chronic bronchitis. The traditional Chinese medicine comprises the following active pharmaceutical ingredients: white mustard seed, membranous milkvetch root, bitter apricot seed, cassia twig, honeysuckle flower, inula flower, manchurian wildginger, Chinese date, saffron, cattail pollen, amur corktree bark, radish seed, mulberry leaf, common macrocarpium fruit, coix seed, immature bitter orange, tangerine peel, dried ginger and rubus corchorifolius leaf. Compared with western medicine treatment, the traditional Chinese medicine can be used for treatment on the whole, and has the advantages of no toxicity, no side effect, no medicament resistance, good effect and no recurrence of diseases.
Description
Technical field
The present invention relates to technical field of Chinese medicine, particularly relate to a kind of Chinese medicine being used for the treatment of chronic bronchitis.
Background technology
Chronic bronchitis is by infecting or the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa that non-infective agent causes and surrounding tissue, is common clinical, frequently-occurring disease.Be apt to occur in winter and spring, recurrent exerbation, touching difficulty more.
Society tobacco and wine culture prevailing, for the doings of people provide auxiliary element, but also bring threat for the healthy of people, tobacco and wine are also one of factors of bringing out chronic bronchitis simultaneously.Life stress causes work fatigue, and overtired is also one of reason of bringing out this disease, and courses of infection, virus, irritative gas, cold weather etc. all can cause bronchial mucosa impaired in addition, bring out the generation of chronic bronchitis diseases.
This disease is clinical in cough, companion's expectoration, pants for feature, can concurrent obstructive emphysema even pulmonary heart disease time serious, causes patient respiratory difficulty or heart failure.Any ages crowd all can fall ill, be more common in middle-aged and elderly people, according to interrelated data display, the sickness rate of China's more than 50 years old crowd's chronic bronchitis is about 15%, day by day increasing the weight of in recent years along with aged tendency of population and environmental pollution, its sickness rate is more and more higher.Patient has allergies, prolonged and repeated virus and bacteriological infection, and immunity of organisms reduces and some chemical factors etc. can bring out primary disease, with multiple when cold season autumn and winter or temperature cataclysm.Patient Chang Yin recurrent exerbation, protracted course of disease, the course of disease are long and Multiple Hospitalization is treated, and not only can have a strong impact on the quality of life of patient, and can increase the burden of patient home and society.
Western medical treatment all selects antiinflammatory, apophlegmatisant, generally uses antibiotic therapy, and symptom can be alleviated, but cough, expectoration easily recurs, and side effect is more.Treatment easily produces drug resistance to antibiotic and antiviral drugs repeatedly, causes curative effect to decline.Western medical treatment biases toward anti symptom treatment more, for recurrent exerbation patient, is often difficult to obtain good effect.
Chronic bronchitis patient has cough, white, the uncomfortable in chest asthma of expectorant more and meets the heavy performance of cold rnning, the many genus of Chinese medical discrimination are suffered from a deficiency of the kidney and are not received, stagnation of phlegm-damp, therefore with " organic conception " " treatment must aim at the pathogenesis of disease " " treating both the principal and secondary aspects of a disease " for Therapeutic Principle, there is the advantage that western medical treatment does not have.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine being used for the treatment of chronic bronchitis,
Relative to western medical treatment, it can be treated on the whole, has no side effect and drug resistance, respond well, and the state of an illness is not repeatedly.
Accordingly, the invention provides a kind of Chinese medicine being used for the treatment of chronic bronchitis, its crude drug comprises:
Semen Sinapis Albae, the Radix Astragali, Semen Armeniacae Amarum, Ramulus Cinnamomi, Flos Lonicerae, Flos Inulae, Herba Asari, Fructus Jujubae, Stigma Croci, Pollen Typhae, Cortex Phellodendri, Semen Raphani, Folium Mori, Fructus Corni, Semen Coicis, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae, Rhizoma Zingiberis and compound in rubus corchorifolius leaf.
Wherein, described Chinese medicine is only made up of above-mentioned raw materials medicine component.
Wherein, in described Chinese medicine, the weight portion of each crude drug is respectively Semen Sinapis Albae 22 ~ 28 weight portion, the Radix Astragali 41 ~ 53 weight portion, Semen Armeniacae Amarum 27 ~ 35 weight portion, Ramulus Cinnamomi 37 ~ 46 weight portion, Flos Lonicerae 18 ~ 26 weight portion, Flos Inulae 12 ~ 19 weight portion, Herba Asari 19 ~ 25 weight portion, Fructus Jujubae 27 ~ 33 weight portion, Stigma Croci 21 ~ 28 weight portion, Pollen Typhae 18 ~ 23 weight portion, Cortex Phellodendri 30 ~ 40 weight portion, Semen Raphani 32 ~ 37 weight portion, Folium Mori 22 ~ 29 weight portion, Fructus Corni 35 ~ 41 weight portion, Semen Coicis 20 ~ 29 weight portion, Fructus Aurantii Immaturus 30 ~ 36 weight portion, Pericarpium Citri Reticulatae 26 ~ 30 weight portion, Rhizoma Zingiberis 27 ~ 33 weight portion and compound in rubus corchorifolius leaf 15 ~ 23 weight portion.
Wherein, in described Chinese medicine, the weight portion of each crude drug is respectively Semen Sinapis Albae 26 weight portion, the Radix Astragali 46 weight portion, Semen Armeniacae Amarum 31 weight portion, Ramulus Cinnamomi 41 weight portion, Flos Lonicerae 22 weight portion, Flos Inulae 16 weight portion, Herba Asari 22 weight portion, Fructus Jujubae 30 weight portion, Stigma Croci 25 weight portion, Pollen Typhae 20 weight portion, Cortex Phellodendri 35 weight portion, Semen Raphani 35 weight portion, Folium Mori 26 weight portion, Fructus Corni 38 weight portion, Semen Coicis 25 weight portion, Fructus Aurantii Immaturus 33 weight portion, Pericarpium Citri Reticulatae 29 weight portion, Rhizoma Zingiberis 30 weight portion and compound in rubus corchorifolius leaf 20 weight portion.
Wherein, described Chinese medicine can be prepared into syrup and granule.
The preparation method of Chinese medicine provided by the invention, when the dosage form of described Chinese medicine is granule, is specially:
Above-mentioned raw materials medicine component is mixed in proportion, decoct with water twice, add for 1st time relative to mixture quality 6 ~ 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 4 ~ 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, add relative to dry powder quality 20% ~ 30% cane sugar powder (mass percent) subsequently, be 75% ~ 85% ethanol soft material with determining alcohol, granulate with oscillating granulator, dry at 60 DEG C, granulate, obtain granule.
The preparation method of Chinese medicine provided by the invention, when the dosage form of described Chinese medicine is syrup, is specially:
Above-mentioned raw materials medicine component is mixed in proportion, decoct with water twice, add for 1st time relative to mixture quality 6 ~ 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 4 ~ 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, get 100 weight portion dry powder, 3 weight portion ~ 5 weight portion sodium carboxymethyl cellulose, the sucrose of 30 weight portion ~ 50 weight portions, the sodium benzoate of 0.5 weight portion ~ 1 weight portion is dispersed in water, stirring and evenly mixing, obtaining crude drug concentration is the solution of 3g/ml ~ 5g/ml, boil and make dissolving, filter, subpackage after sterilizing, obtain syrup.
Beneficial effect of the present invention:
Chinese medicine provided by the invention is in treatment chronic bronchitis, and relative to western medical treatment, it can be treated on the whole, has no side effect and drug resistance, respond well, and the state of an illness is not repeatedly.
Detailed description of the invention
Motherland's medical science thinks that chronic tracheitis belongs to the category such as " cough ", " phlegm retention ", " the syndrome of dyspnea ", and how because of the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens, because the course of disease is longer, latent phlegm hinders in lung, injures lungs, and pathogenesis is that yang deficiency is drunk and stopped,
The cough that chronic bronchitis patient is permanent, outbreak often and repeatedly, cause disease and spleen kidney,
Thus make spleen-kidney vacuity cold, old complaint and disease originally do not reach firmly, purplish tongue or light, arteries and veins many and heavy thin, tongue is white.During lung kidney in the morbidity of chronic bronchitis and body is insufficiency of the spleen etc., the deficiency of healthy energy and exopathogen invade relation.The cardinal symptom of chronic bronchitis shows as repeatedly coughs up phlegm, coughs, and the basis of its cause of disease is mainly the interior volt of phlegm retention and the imbalance of internal organs.
The total pathogenesis of this disease is because diseases caused by exogenous pathogenic factor six evil causes impairment of purifying and descending function of the lung, and cough, expectorant, breathe heavily all diseases and in succession occur, with the passing of time injure spleen kidney, it is marked on lung, and it is at spleen kidney.Have Exogenous and internal injuries point, diseases caused by exogenous pathogenic factor person attacks for six climate exopathogens are taken advantage of, and internal injury is many injures spleen kidney because of prolonged illness.Qing Dynasty Shen Jin huge legendary turtle is pointed out in " miscellaneous diseases source and course rhinoceros candle cough, asthma source and course ": " lid lung is not hindered and do not coughed, and spleen does not hinder not chronic cough, and it is not vehement that kidney does not hinder fire, coughs not very, and it greatly more also." illustrate lung spleen kidney three dirty be the major lesions place of cough, spleen insufficiency water liquid, accumulation and obstruction of sputum, causes impairment of dispersing and descending function of the lung, abnormal rising of lung-QI and falling ill.Suffer from a deficiency of the kidney and not improving inspiration by invigorating kidney-QI frequently do to panting.
Therefore, primary disease treatment should be main with " invigorating the spleen and benefiting QI the kidney invigorating, relieving cough and resolving phlegm is relievingd asthma ".
Accordingly, the invention provides a kind of Chinese medicine being used for the treatment of chronic bronchitis, its crude drug comprises:
Semen Sinapis Albae, the Radix Astragali, Semen Armeniacae Amarum, Ramulus Cinnamomi, Flos Lonicerae, Flos Inulae, Herba Asari, Fructus Jujubae, Stigma Croci, Pollen Typhae, Cortex Phellodendri, Semen Raphani, Folium Mori, Fructus Corni, Semen Coicis, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae, Rhizoma Zingiberis and compound in rubus corchorifolius leaf.
Fang Zhong, Semen Sinapis Albae has the use of warming the lung eliminating phlegm promoting the circulation of QI, the Radix Astragali, return liver spleen kidney three warp, there is the effect of benefiting QI for strengthening the superficies, Semen Armeniacae Amarum relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, it can control the maincenter of coughing, Ramulus Cinnamomi warming yang for resolving fluid retention, Flos Lonicerae has good antibacterial, antiviral efficacy, the acute lung injury of endotaxin induction can also be suppressed, to the treatment of chronic bronchitis, there is help, Flos Inulae can be alleviated bronchial spasm thus relieving asthma, Herba Asari, Stigma Croci contains reduction bronchial secretion and antianaphylactic spasmolysis, Fructus Jujubae can increase its hemoglobin, and the regeneration of hemocyte can be promoted, Pollen Typhae has microthrombus in reasonable removing diseased region and antianaphylactic effect unique, Cortex Phellodendri is good at part of the body cavity above the diaphragm housing the heart and lungs lung-fire clearly, expectorant promoting the circulation of QI Dingchuan is coughed, Semen Raphani energy lowering the adverse-rising QI to resolve phlegm, relieving cough and asthma, You Yizhi cough expectorant is stopped up, Folium Mori have dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, effect of clearing away lung-heat to relieve cough, Fructus Corni, Galla Chinensis the kidney warming improving inspiration by invigorating kidney-QI, relieving cough and asthma, Semen Coicis is strong turns round and look at taste, exhausted the source of producing phlegm, Fructus Aurantii Immaturus can stimulate throat mucosa, reflexive causes respiratory mucosa hypersecretion, there is obvious phlegm-dispelling functions, Pericarpium Citri Reticulatae has peace stomach of regulating the flow of vital energy, the effect of drying dampness to eliminate phlegm, Rhizoma Zingiberis warming spleen and stomach for dispelling cold, warming the lung to resolve fluid-retention, compound in rubus corchorifolius leaf relieving sore-throat by clearing away heat, removing toxic substances sore, all medicines share, realize invigorating the spleen and benefiting QI the kidney invigorating, the treatment that relieving cough and resolving phlegm is relievingd asthma.
Each crude drug pharmacology is as follows:
Semen Sinapis Albae: the dry mature seed of crucifer Caulis et Folium Sinapis albee, latin name
sinapis Semen, acrid in the mouth, hot in nature, have warming the lung eliminating phlegm promoting the circulation of QI, effect of resolving mass and removing the obstruction of the collateral pain relieving, breathes with cough for cold-phlegm, distending pain in the chest and hypochondrium, the stagnant meridians of expectorant, joint numbness, pain, phlegm-damp oozing in the body, the cards such as carbuncle of yin nature toxic swelling.
The Radix Astragali: sweet in the mouth, warm in nature, enter spleen, lung meridian, have tonification spleen soil, elevate a turnable ladder yang-energy, strengthening superficial resistance to stop perspiration, the effects such as holder skin ulcer granulation promoting, are mainly used in the weak anorexia and loose stool that deficiency of both the splenic and pulmonary QI is caused, shortness of breath and palpitation, the visceroptosis of sinking of QI of middle-JIAO, the metrorrhagia of QI failing to control blood is had blood in stool, chronic diarrhea proctoptosis; The spontaneous sweating of exterior deficiency, the cards such as insufficiency of vital energy and blood.
Semen Armeniacae Amarum: bitter in the mouth, pungent, slightly warm in nature, enters spleen, lung two warp, there is lung qi dispersing cough-relieving, lowering the adverse-rising QI to subdue asthma, loosening bowel to relieve constipation, effect of parasite killing removing toxic substances, cures mainly cough, dyspnea with rapid and short breath fullness in the chest, sore throat pharyngalgia, dryness of the intestine constipation, the cards such as insect poison skin infection, Compendium of Material Medica: earnestly Semen Armeniacae Amarum can fall apart and can fall, therefore expelling pathogenic factors from muscles, loose wind, sending down the abnormal ascending QI, moisturize, removing food stagnancy, cure the wound to damage in medicine and use it.Control skin ulcer parasite killing, with its poison also.Control in wind and cold pectoral, also have gross weight point user, get it and disperse also.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature, GUIXIN, lung, urinary bladder channel, have diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, the effect of dispersing cold for relieving pain, Ramulus Cinnamomi warming the meridian and promoting blood circulation, horizontal logical podomere, for affection of exogenous wind-cold exterior syndrome, no matter have antiperspirant, losslessly all can to apply, also for rheumatic arthralgia, cold syndrome of the stomach stomachache, amenorrhea, dysmenorrhea, rheumatic arthralgia, the cards such as shoulder arm podomere cold type of pain, phlegm retention syndrome and bladder water-retention, heart deficiency of spleen-YANG, retention of water-damp in the body, fullness and distention in the chest and hypochondrium, cough with dyspnea dizziness waits phlegm retention syndrome.
Flos Lonicerae: sweet in the mouth, cold in nature, enters the heart, lung, stomach, large intestine channel, has the effect of heat-clearing and toxic substances removing, and holding concurrently can eliminating pathogenic heat from blood to cure dysentery.Be mainly used in affection due to external wind and heat, epidemic febrile disease pyretic toxicity is comparatively contained, or when epidemic febrile disease is still not descending at the part of the body cavity above the diaphragm housing the heart and lungs from the beginning of pathogenic heat; Pyretic toxicity dysentery, stool hematochezia; Fever disease in summer is demonstrate,proved; The carbuncle sore that pyretic toxicity gathers is from the beginning of the, inflammation heat person of swelling and ache etc., Flos Lonicerae has good antipyretic effect, energy antiinflammatory, what control inflammation oozes out and inflammatory hyperplasia, can leukocytic phagocytic function be promoted, have stronger bacteriostasis to multiple pyococcus and pathogenic entero becteria, comprise staphylococcus, Hemolytic streptococcus, meningococcus, dysentery bacterium, Bacillus typhi, bacillus pyocyaneus, tubercule bacillus etc., the pyretic toxicity that Flos Lonicerae is divided QI and blood battalion is all effective, and has broad-spectrum antibacterial action.
Flos Inulae: the first system of its taste with salty, relaxing the bowels with lubricant drugs is done salty, salty energy softening the hard mass; " not Lu " to sweet taste in the mouth, in Gan Nenghuan; Tepor, temperature can be passed through, therefore main stagnation of QI fullness in the hypochondrium; Heart spleen latent fluid-retention is sick palpitation with fear then, and drink disappears then multiple normal.Dewater, remove cold and heat between the five internal organs, and expectorant knot on the breast that disappears, saliva is as shellac varnish, and heart side of body expectorant water, wing is prolonged fluid-retention all of a sudden, pathogenic wind arthralgia chiefly caused by damp pathogen, and between skin, dead flesh, opens in order, sharp large intestine person, and all softening the hard mass, cold profit, relaxing the bowels with lubricant drugs, expectorant drink the merit that dewaters also.It says invigorating middle warmer therapeutic method to keep the adverse QI flowing downwards person, in slow with sweet energy, salty can relaxing the bowels with lubricant drugs therefore also.Promoting blood circulation, beneficial color and luster person, lid refers to that the drink then spleen that disappears is good for, strong then can run, and spleen is wrapped up in blood and to be united again blood therefore also.
Herba Asari: latin name
asari Radix et Rhizoma, acrid in the mouth, warm in nature, return lung, kidney channel, there is expelling wind and cold pain relieving, effect that warming the lung to resolve fluid-retention is sensible, cure mainly affection of exogenous wind-cold, headache, toothache, wind and cold temperature numbness, affection of exogenous wind-cold, in stop lung cold cough with asthma caused by cold fluid-retention, nasal obstruction nasal sinusitis, wind-eye corneal nebula, deafness pharyngalgia, the cards such as aphtha halitosis, Herba Asari has obvious inhibitory action to cellular immunization and humoral immunization.
Fructus Jujubae: sweet in the mouth, slightly warm in nature, have invigorating the spleen and replenishing QI, effect of nourishing blood to tranquillize the mind, returns spleen, stomach warp, cures mainly weakness of the spleen and stomach, deficiency of QI in middle-JIAO, fatigue and lack of strength, anorexia and loose stool; Blood deficiency fistula is yellow, become thin, or women is dirty dry, and spirit is uneasy waits card.
Stigma Croci: sweet in the mouth, property is put down, energy blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens, pain relieving.Be used for the treatment of troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, and spit blood, typhoid fever is gone mad, and frightened fear in a trance, women's amenorrhea, stasis menoxenia, prolonged lochia, blood stasis is had a pain, measles, the cards such as traumatic injury.
Pollen Typhae: sweet in the mouth, property is put down, and enters liver, pericardium channel, has hemostasis, blood stasis dispelling, treating stranguria effect.For spitting blood, epistaxis, spitting of blood, metrorrhagia, traumatic hemorrhage, amenorrhea dysmenorrhea, gastral cavity ventral spine pain, tumbling and swelling, the cards such as blood strangury and dry pain.
Cortex Phellodendri: latin name
phellodendri Chinensis Cortex,bitter in the mouth, cold in nature, enter kidney, bladder, large intestine channel, heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, and seminal emission, sore swollen toxin, the cards such as eczema pruritus, Cortex Phellodendri has good antibacterial action to multiple gram-positive bacterium.
Semen Raphani: property is put down, acrid in the mouth, sweet, returns lung, spleen, stomach warp, has the de-swelling that helps digestion, effect of lowering the adverse-rising QI to resolve phlegm, cures mainly retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant stops up cards such as breathing with cough.
Folium Mori: sweet in the mouth are bitter; Cold in nature.Return lung, Liver Channel, there is dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving, the effect of cooling blood for hemostasis, for anemopyretic cold and conjunctival congestion and swelling pain, wind-fire order disease, the few expectorant of dryness-heat impairing the lung, dry cough, " Bencao Jingshu ": " herbal classic " odorlessness.It cures mainly in detail, should be that sweet in the mouth gas is cold nontoxic.Sweet so beneficial blood, cold so removing heat from blood, to be sweetly coldly harmonious, therefore the therapeutic method to keep the adverse QI flowing downwards and tonifying YIN.With the main deficiency of YIN cold and heat of energy, and because of interior-heat perspiration.Its property is held concurrently dry, therefore can remove beriberi edema, sharp intestine and small intestine again.The golden gas of former official report, therefore can wind be removed again.Then to get both the respectful clearly of the world through frost, therefore again can improving eyesight and quenching the thirst.Originator, the leeway of blood, beneficial blood therefore again can long hair, removing heat from blood therefore emesis blood again.Close carbuncle mouth, the palm worn by net for catching birds or fish, and treat soup fire, all refrigerant merit of enriching blood also.
Fructus Corni: sour in the mouth, puckery, slightly warm in nature, returns liver, kidney channel, has liver and kidney tonifying, effect of essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat such as to be quenched one's thirst at the card.
Semen Coicis: cool in nature, sweet in the mouth, light, return spleen, stomach, lung meridian.Have the function of spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, diuretic, for weakness of the spleen and stomach, suffer from diarrhoea in loose stool, or vaginal discharge diseases of women, insufficiency of the spleen leading to overabundance of dampness edema, dysuria, or beriberi swells and ache; Damp and hot arthralgia pain, contracture of the limbs, miserable pain; Lung abscess cough and spit purulent sputum, or enterodynia contracture stomachache.
Fructus Aurantii Immaturus: bitter in the mouth, pungent, cold nature, enters spleen, stomach warp, has dispelling the stagnated QI removing food stagnancy, expectorant except the effect of painful abdominal mass, be mainly used in stagnant in stop, the YangmingFushi syndrome of distension and fullness in the abdomen, constipation.
Pericarpium Citri Reticulatae: warm in nature, acrid in the mouth, hardship; Return spleen, lung meridian, pungent loose logical temperature, fragrant odour, is longer than and regulates the flow of vital energy, and can enter spleen lung, therefore can go loose sluggishness of lung-QI, again can promoting the circulation of QI to alleviate the stagnation in middle-JIAO, gathers around stagnant, chest and diaphragm feeling of fullness and the card such as stagnation of QI in spleen and stomach, distension and fullness in the abdomen for lung qi.
Rhizoma Zingiberis: acrid in the mouth, hot in nature, return spleen, stomach, the heart, lung meridian; Have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, effect of warming the lung to resolve fluid-retention, and for coldness and pain in the epigastrium, vomiting, has loose bowels, the cards such as YANG-depletion is fainted inverse, and cold fluid-retention is breathed with cough, arthralgia due to cold-dampnes.
Compound in rubus corchorifolius leaf: bitter in the mouth, puckery, property is put down, and has relieving sore-throat by clearing away heat, and effect of removing toxic substances sore, cures mainly laryngopharynx swelling and pain, carbuncle sore furuncle and phyma, mastitis, the cards such as eczema.
Preferably, described Chinese medicine is only made up of above-mentioned raw materials medicine component.
In described Chinese medicine, the weight portion of each crude drug is respectively Semen Sinapis Albae 22 ~ 28 weight portion, the Radix Astragali 41 ~ 53 weight portion, Semen Armeniacae Amarum 27 ~ 35 weight portion, Ramulus Cinnamomi 37 ~ 46 weight portion, Flos Lonicerae 18 ~ 26 weight portion, Flos Inulae 12 ~ 19 weight portion, Herba Asari 19 ~ 25 weight portion, Fructus Jujubae 27 ~ 33 weight portion, Stigma Croci 21 ~ 28 weight portion, Pollen Typhae 18 ~ 23 weight portion, Cortex Phellodendri 30 ~ 40 weight portion, Semen Raphani 32 ~ 37 weight portion, Folium Mori 22 ~ 29 weight portion, Fructus Corni 35 ~ 41 weight portion, Semen Coicis 20 ~ 29 weight portion, Fructus Aurantii Immaturus 30 ~ 36 weight portion, Pericarpium Citri Reticulatae 26 ~ 30 weight portion, Rhizoma Zingiberis 27 ~ 33 weight portion and compound in rubus corchorifolius leaf 15 ~ 23 weight portion.
Further preferably, in described Chinese medicine, the weight portion of each crude drug is respectively Semen Sinapis Albae 26 weight portion, the Radix Astragali 46 weight portion, Semen Armeniacae Amarum 31 weight portion, Ramulus Cinnamomi 41 weight portion, Flos Lonicerae 22 weight portion, Flos Inulae 16 weight portion, Herba Asari 22 weight portion, Fructus Jujubae 30 weight portion, Stigma Croci 25 weight portion, Pollen Typhae 20 weight portion, Cortex Phellodendri 35 weight portion, Semen Raphani 35 weight portion, Folium Mori 26 weight portion, Fructus Corni 38 weight portion, Semen Coicis 25 weight portion, Fructus Aurantii Immaturus 33 weight portion, Pericarpium Citri Reticulatae 29 weight portion, Rhizoma Zingiberis 30 weight portion and compound in rubus corchorifolius leaf 20 weight portion.
The Chinese medicine being used for the treatment of chronic bronchitis provided by the invention can be prepared into any regular dosage form, is preferably prepared into syrup and granule.
The preparation method of Chinese medicine provided by the invention, when the dosage form of described Chinese medicine is granule, is specially:
Above-mentioned raw materials medicine component is mixed in proportion, decoct with water twice, add for 1st time relative to mixture quality 6 ~ 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 4 ~ 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, add relative to dry powder quality 20% ~ 30% cane sugar powder (mass percent) subsequently, be 75% ~ 85% ethanol soft material with determining alcohol, granulate with oscillating granulator, dry at 60 DEG C, granulate, obtain granule.
The preparation method of Chinese medicine provided by the invention, when the dosage form of described Chinese medicine is syrup, is specially:
Above-mentioned raw materials medicine component is mixed in proportion, decoct with water twice, add for 1st time relative to mixture quality 6 ~ 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 4 ~ 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, get 100 weight portion dry powder, 3 weight portion ~ 5 weight portion sodium carboxymethyl cellulose, the sucrose of 30 weight portion ~ 50 weight portions, the sodium benzoate of 0.5 weight portion ~ 1 weight portion is dispersed in water, stirring and evenly mixing, obtaining crude drug concentration is the solution of 3g/ml ~ 5g/ml, boil and make dissolving, filter, subpackage after sterilizing, obtain syrup.
Below adopt embodiment to describe embodiments of the present invention in detail, to the present invention, how application technology means solve technical problem whereby, and the implementation procedure reaching technique effect can fully understand and implement according to this.
Embodiment 1
By Semen Sinapis Albae 26g, Radix Astragali 46g, Semen Armeniacae Amarum 31g, Ramulus Cinnamomi 41g, Flos Lonicerae 22g, Flos Inulae 16g, Herba Asari 22g, Fructus Jujubae 30g, Stigma Croci 25g, Pollen Typhae 20g, Cortex Phellodendri 35g, Semen Raphani 35g, Folium Mori 26g, Fructus Corni 38g, Semen Coicis 25g, Fructus Aurantii Immaturus 33g, Pericarpium Citri Reticulatae 29g, Rhizoma Zingiberis 30g and compound in rubus corchorifolius leaf 20g mixes, and decocts with water twice, adds for the 1st time relative to mixture quality 8 times of water gagings, decocts 2 hours, add for 2nd time relative to mixture quality 6 times of water gagings, decoct 1 hour, filter, merging filtrate, is concentrated into every 1ml about containing the clear paste of 1g medical material, adds hydrochloric acid and adjusts pH to be 1, limit edged stirs, and leaves standstill, with siphonage sucking-off supernatant, precipitate sucking filtration, to dry, wash with water to without obviously acid, takes out drying precipitate, pulverize, obtain dry powder, get 100g dry powder, 4g sodium carboxymethyl cellulose, the sucrose of 50g, the sodium benzoate of 0.5g is dispersed in water, stirring and evenly mixing, and obtaining crude drug concentration is the solution of 4g/ml, boils and makes dissolving, and filter, subpackage after sterilizing, obtains syrup.
Embodiment 2
By Semen Sinapis Albae 22g, Radix Astragali 41g, Semen Armeniacae Amarum 27g, Ramulus Cinnamomi 37g, Flos Lonicerae 18g, Flos Inulae 12g, Herba Asari 19g, Fructus Jujubae 27g, Stigma Croci 21g, Pollen Typhae 18g, Cortex Phellodendri 30g, Semen Raphani 32g, Folium Mori 22g, Fructus Corni 35g, Semen Coicis 20g, Fructus Aurantii Immaturus 30g, Pericarpium Citri Reticulatae 26g, Rhizoma Zingiberis 27g and compound in rubus corchorifolius leaf 15g mixes, and decocts with water twice, adds for the 1st time relative to mixture quality 8 times of water gagings, decocts 2 hours, add for 2nd time relative to mixture quality 6 times of water gagings, decoct 1 hour, filter, merging filtrate, is concentrated into every 1ml about containing the clear paste of 1g medical material, adds hydrochloric acid and adjusts pH to be 1, limit edged stirs, and leaves standstill, with siphonage sucking-off supernatant, precipitate sucking filtration, to dry, wash with water to without obviously acid, takes out drying precipitate, pulverize, obtain dry powder, get 100g dry powder, 4g sodium carboxymethyl cellulose, the sucrose of 50g, the sodium benzoate of 0.5g is dispersed in water, stirring and evenly mixing, and obtaining crude drug concentration is the solution of 4g/ml, boils and makes dissolving, and filter, subpackage after sterilizing, obtains syrup.
Embodiment 3
By Semen Sinapis Albae 28g, Radix Astragali 53g, Semen Armeniacae Amarum 35g, Ramulus Cinnamomi 46g, Flos Lonicerae 26g, Flos Inulae 19g, Herba Asari 25g, Fructus Jujubae 33g, Stigma Croci 28g, Pollen Typhae 23g, Cortex Phellodendri 40g, Semen Raphani 37g, Folium Mori 29g, Fructus Corni 41g, Semen Coicis 29g, Fructus Aurantii Immaturus 36g, Pericarpium Citri Reticulatae 30g, Rhizoma Zingiberis 33g and compound in rubus corchorifolius leaf 23g mixes, and decocts with water twice, adds for the 1st time relative to mixture quality 8 times of water gagings, decocts 2 hours, add for 2nd time relative to mixture quality 6 times of water gagings, decoct 1 hour, filter, merging filtrate, is concentrated into every 1ml about containing the clear paste of 1g medical material, adds hydrochloric acid and adjusts pH to be 1, limit edged stirs, and leaves standstill, with siphonage sucking-off supernatant, precipitate sucking filtration, to dry, wash with water to without obviously acid, takes out drying precipitate, pulverize, obtain dry powder, get 100g dry powder, 4g sodium carboxymethyl cellulose, the sucrose of 50g, the sodium benzoate of 0.5g is dispersed in water, stirring and evenly mixing, and obtaining crude drug concentration is the solution of 4g/ml, boils and makes dissolving, and filter, subpackage after sterilizing, obtains syrup.
Embodiment 4 granule
Semen Sinapis Albae 26g, Radix Astragali 46g, Semen Armeniacae Amarum 31g, Ramulus Cinnamomi 41g, Flos Lonicerae 22g, Flos Inulae 16g, Herba Asari 22g, Fructus Jujubae 30g, Stigma Croci 25g, Pollen Typhae 20g, Cortex Phellodendri 35g, Semen Raphani 35g, Folium Mori 26g, Fructus Corni 38g, Semen Coicis 25g, Fructus Aurantii Immaturus 33g, Pericarpium Citri Reticulatae 29g, Rhizoma Zingiberis 30g and compound in rubus corchorifolius leaf 20g mixes, decoct with water twice, add for 1st time relative to mixture quality 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, get dry powder 100g, add 25g cane sugar powder subsequently, be 75% ethanol soft material with determining alcohol, granulate with oscillating granulator, dry at 60 DEG C, granulate, obtain granule.
Embodiment 5 clinical data
Physical data
In April, 2010 ~ 2011 are selected to carry out 172 routine patients for the treatment of of chronic bronchitis in the author place hospital for object of study year April.Man 95 example, female 77 example, 13 ~ 75 years old age, average (45.0 ± 9.2) year, all patients all have certain cough, have sore throat before being admitted to hospital, sputum is sticky and in white, have wheezing sound, the symptom such as difficulty of breathing, health are weak, heating, the course of disease 2 months ~ 8 years.172 routine patients are divided into matched group and treatment group by its therapeutic modality difference.Treatment group 90 example, matched group 82 example.Two groups of patients are through statistical procedures in age, sex, the course of disease, risk factor, and no significant difference (P > 0.05), has comparability.
Therapeutic Method
The syrup that treatment group adopts the embodiment of the present invention 1 to prepare is treated, every day 3 times, each 1 bottle, every bottle of 10ml, while treatment, give adjustment on minimal invasive treatment and nursing and spiritual encouragement and comfort more, be careful in one's diet nutrition, and the food of polyphagia moistening the lung and resolving phlegm and high protein, homovitamin food, eliminate and avoid the suction of mist, dust and irritative gas, enhancing body resistance, improves clinical efficacy.
It is each that matched group gives Ceruroxime axetil capsules 0.25g, and every day 2 times is oral, and aminophylline tablets 100 ㎎ is each, and every day 3 times is oral.
All treat 2 courses for the treatment of for two groups.
Efficacy determination
Cure: the transference cures such as cough, expectoration, wheezing sound, breathe normal, X line sheet is normal; Effective: the symptoms such as cough, expectoration, wheezing sound have clear improvement, and breathing has slight difficulty once in a while, and X line sheet recovery situation reaches more than 85%; Effective: the symptoms such as cough, expectoration, wheezing sound make moderate progress, some difficulty of breathing, X line sheet recovery situation reaches more than 60%; Invalid: the symptoms such as cough, expectoration, wheezing sound are without improvement, and difficulty of breathing, X line sheet recovery situation is below 60%.
Inclusive criteria
(1) meet " diagnostic criteria that Chinese Medical Association's Pneumology Department meeting is determined "; (2) 10 ~ 80 years old age; (3) doctor can be accepted and carry out every detection; (4) without other primary diseases or psychosis medical history.
Statistical procedures
Adopt SPSS17.0 statistics software to analyze, contrast the cough of two groups of patients, expectoration, wheezing sound and X line sheet recovery situation, P < 0.05 has statistical significance for difference.
Therapeutic outcome
Before and after two groups of patient treatments, each condition of illness contrast, the results are shown in Table 1.
Before and after table 1 liang group patient treatment, each condition of illness compares (n)
After two courses for the treatment of, the comparitive study of two groups of patients, the results are shown in Table 2.
The comparitive study of table 2 liang group patient
| Group | n | Cure | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 90 | 52 | 26 | 10 | 2 | 97.8% |
| Matched group | 82 | 32 | 27 | 13 | 10 | 87.8% |
Can be found out by table 1 and table 2, adopt Chinese materia medica syrup of the present invention to have good curative effect in treatment chronic bronchitis.
All above-mentioned this intellectual properties of primary enforcement, not setting restriction this new product of other forms of enforcement and/or new method.Those skilled in the art will utilize this important information, and foregoing is revised, to realize similar implementation status.But all modifications or transformation belong to the right of reservation based on new product of the present invention.
The above is only preferred embodiment of the present invention, and be not restriction the present invention being made to other form, any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the Equivalent embodiments of equivalent variations.But everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done above embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
Claims (5)
1. one kind is used for the treatment of the Chinese medicine of chronic bronchitis, it is characterized in that, the crude drug of described Chinese medicine is only made up of Semen Sinapis Albae, the Radix Astragali, Semen Armeniacae Amarum, Ramulus Cinnamomi, Flos Lonicerae, Flos Inulae, Herba Asari, Fructus Jujubae, Stigma Croci, Pollen Typhae, Cortex Phellodendri, Semen Raphani, Folium Mori, Fructus Corni, Semen Coicis, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae, Rhizoma Zingiberis and compound in rubus corchorifolius leaf, in described Chinese medicine, the weight portion of each crude drug is respectively Semen Sinapis Albae 22 ~ 28 weight portion, the Radix Astragali 41 ~ 53 weight portion, Semen Armeniacae Amarum 27 ~ 35 weight portion, Ramulus Cinnamomi 37 ~ 46 weight portion, Flos Lonicerae 18 ~ 26 weight portion, Flos Inulae 12 ~ 19 weight portion, Herba Asari 19 ~ 25 weight portion, Fructus Jujubae 27 ~ 33 weight portion, Stigma Croci 21 ~ 28 weight portion, Pollen Typhae 18 ~ 23 weight portion, Cortex Phellodendri 30 ~ 40 weight portion, Semen Raphani 32 ~ 37 weight portion, Folium Mori 22 ~ 29 weight portion, Fructus Corni 35 ~ 41 weight portion, Semen Coicis 20 ~ 29 weight portion, Fructus Aurantii Immaturus 30 ~ 36 weight portion, Pericarpium Citri Reticulatae 26 ~ 30 weight portion, Rhizoma Zingiberis 27 ~ 33 weight portion and compound in rubus corchorifolius leaf 15 ~ 23 weight portion.
2. Chinese medicine as claimed in claim 1, it is characterized in that: in described Chinese medicine, the weight portion of each crude drug is respectively Semen Sinapis Albae 26 weight portion, the Radix Astragali 46 weight portion, Semen Armeniacae Amarum 31 weight portion, Ramulus Cinnamomi 41 weight portion, Flos Lonicerae 22 weight portion, Flos Inulae 16 weight portion, Herba Asari 22 weight portion, Fructus Jujubae 30 weight portion, Stigma Croci 25 weight portion, Pollen Typhae 20 weight portion, Cortex Phellodendri 35 weight portion, Semen Raphani 35 weight portion, Folium Mori 26 weight portion, Fructus Corni 38 weight portion, Semen Coicis 25 weight portion, Fructus Aurantii Immaturus 33 weight portion, Pericarpium Citri Reticulatae 29 weight portion, Rhizoma Zingiberis 30 weight portion and compound in rubus corchorifolius leaf 20 weight portion.
3
.chinese medicine as claimed in claim 1 or 2, is characterized in that: described Chinese drug preparation becomes syrup and granule.
4
.the preparation method of Chinese medicine described in claim 1 or 2, is characterized in that: when the dosage form of described Chinese medicine is granule, be specially,
Described crude drug component is mixed in proportion, decoct with water twice, add for 1st time relative to mixture quality 6 ~ 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 4 ~ 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, add relative to dry powder quality 20% ~ 30% cane sugar powder (mass percent) subsequently, be 75% ~ 85% ethanol soft material with determining alcohol, granulate with oscillating granulator, dry at 60 DEG C, granulate, obtain granule.
5
.the preparation method of Chinese medicine described in claim 1 or 2, is characterized in that: when the dosage form of described Chinese medicine is syrup, be specially,
Described crude drug component is mixed in proportion, decoct with water twice, add for 1st time relative to mixture quality 6 ~ 8 times of water gagings, decoct 2 hours, add for 2nd time relative to mixture quality 4 ~ 6 times of water gagings, decoct 1 hour, filter, merging filtrate, be concentrated into every 1ml about containing the clear paste of 1g medical material, adding hydrochloric acid adjusts pH to be 1, limit edged stirs, leave standstill, with siphonage sucking-off supernatant, precipitate sucking filtration is to dry, wash with water to nothing obviously acid, take out drying precipitate, pulverize, obtain dry powder, get 100 weight portion dry powder, 3 weight portion ~ 5 weight portion sodium carboxymethyl cellulose, the sucrose of 30 weight portion ~ 50 weight portions, the sodium benzoate of 0.5 weight portion ~ 1 weight portion is dispersed in water, stirring and evenly mixing, obtaining crude drug concentration is the solution of 3g/ml ~ 5g/ml, boil and make dissolving, filter, subpackage after sterilizing, obtain syrup.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310326410.0A CN103341151B (en) | 2013-07-31 | 2013-07-31 | Traditional Chinese medicine for treating chronic bronchitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310326410.0A CN103341151B (en) | 2013-07-31 | 2013-07-31 | Traditional Chinese medicine for treating chronic bronchitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103341151A CN103341151A (en) | 2013-10-09 |
| CN103341151B true CN103341151B (en) | 2015-03-25 |
Family
ID=49276010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310326410.0A Expired - Fee Related CN103341151B (en) | 2013-07-31 | 2013-07-31 | Traditional Chinese medicine for treating chronic bronchitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103341151B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194171A (en) * | 2015-09-23 | 2015-12-30 | 李彬 | Traditional Chinese medicine preparation for treating chronic cardiac failure and edema and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312103A (en) * | 2001-02-23 | 2001-09-12 | 邓万发 | Chinese medicine for treating dyspneic cough effectively |
| CN1733014A (en) * | 2005-08-27 | 2006-02-15 | 孙恩义 | Externally applied plaster for strengthening healthy energy to stop cough and relieve asthma |
| CN101785839A (en) * | 2010-04-23 | 2010-07-28 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine combination and preparation method thereof for hemoptysis treatment |
| CN102397454A (en) * | 2011-11-20 | 2012-04-04 | 武汉卡倍欣科技发展有限公司 | Pill for clearing away lung heat and relieving sore throat |
| CN102552773A (en) * | 2012-02-06 | 2012-07-11 | 孟庆云 | Drug for treating bronchitis and bronchial asthma of 7-15 year old children |
| CN102743730A (en) * | 2012-07-11 | 2012-10-24 | 胡晓斌 | Traditional Chinese medicine wine for treating arthritis and preparation method |
-
2013
- 2013-07-31 CN CN201310326410.0A patent/CN103341151B/en not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312103A (en) * | 2001-02-23 | 2001-09-12 | 邓万发 | Chinese medicine for treating dyspneic cough effectively |
| CN1733014A (en) * | 2005-08-27 | 2006-02-15 | 孙恩义 | Externally applied plaster for strengthening healthy energy to stop cough and relieve asthma |
| CN101785839A (en) * | 2010-04-23 | 2010-07-28 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine combination and preparation method thereof for hemoptysis treatment |
| CN102397454A (en) * | 2011-11-20 | 2012-04-04 | 武汉卡倍欣科技发展有限公司 | Pill for clearing away lung heat and relieving sore throat |
| CN102552773A (en) * | 2012-02-06 | 2012-07-11 | 孟庆云 | Drug for treating bronchitis and bronchial asthma of 7-15 year old children |
| CN102743730A (en) * | 2012-07-11 | 2012-10-24 | 胡晓斌 | Traditional Chinese medicine wine for treating arthritis and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103341151A (en) | 2013-10-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104474471A (en) | Traditional Chinese medicine composition for treating thyroid | |
| CN103735673B (en) | Traditional Chinese medicine preparation for treating infantile pneumonia and preparation method thereof | |
| CN105477487A (en) | Medicine for treating chronic pharyngitis and preparation method thereof | |
| CN104147574A (en) | Heat-clearing and exterior-releasing traditional Chinese medicine composition for treating cold and fever and preparation method thereof | |
| CN105213941A (en) | A kind of Chinese medicine composition being used for the treatment of infantile diarrhea and preparation method thereof | |
| CN104352704A (en) | Formula of traditional Chinese medicine for curing facial neuritis | |
| CN103860955A (en) | Traditional Chinese medicine combination for treating human papillomavirus infection and preparation method of traditional Chinese medicine combination | |
| CN103341151B (en) | Traditional Chinese medicine for treating chronic bronchitis | |
| CN105770074A (en) | Traditional Chinese medicine composition for treating wind-heat common cold and preparation method thereof | |
| CN105663575A (en) | Traditional Chinese medicine composition for preventing and treating swine fever and preparation method of traditional Chinese medicine composition | |
| CN104984280A (en) | Foot soaking decoction for treating exogenous wind-cold and preparation method thereof | |
| CN104998074A (en) | Traditional Chinese medicine for treating gastropathy and preparation method thereof | |
| CN105056078A (en) | Traditional Chinese medicine composition for treating stomach fire exuberance, toothache and ozostomia | |
| CN104257986A (en) | Traditional Chinese medicine for treating nephritis | |
| CN103202951A (en) | Traditional Chinese medicine decoction for treating bronchial asthma | |
| CN103071142A (en) | Quick-acting external patch for tracheitis | |
| CN105963586A (en) | Medicine for treating lung abscess and preparation method thereof | |
| CN105687873A (en) | Preparation for treating nasal polyp, and preparation method of preparation | |
| CN101564510A (en) | Chinese medicament liniment for effectively treating fungal infection of hand | |
| CN105596770A (en) | Externally-used ointment for promoting bone fracture healing and preparation method thereof | |
| CN105106727A (en) | Traditional Chinese medicine composition for treating liver-fire attacking lung type hemoptysis | |
| CN105267499A (en) | Medicament for treatment of urethritis and preparation method | |
| CN104940635A (en) | Scald and burn traditional Chinese medicine compound for external use | |
| CN104758830A (en) | Traditional Chinese medicine composition for treating bone disease and skin injury and preparation method of traditional Chinese medicine composition | |
| CN104189513A (en) | Lymphatic tuberculosis regulating qi-flowing and reducing edema preparation and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150325 Termination date: 20150731 |
|
| EXPY | Termination of patent right or utility model |