CN105031357A - Medicine for treating oral ulcer and preparation method thereof - Google Patents

Abstract

The invention discloses a medicine for treating oral ulcer and a preparation method thereof. The medicine is mainly prepared from burdock, peppermint, cape jasmine, dandelion, rhizoma phragmitis, radix polygonati officinalis, radix rehmanniae praeparata, moutan bark, fructus evodiae, asparagus cochinchinensis, licorice root and rhizoma anemarrhenae in a certain weight ratio. The medicine has functions of clearing heat, removing toxicity, dissipating stasis, cooling blood, diminishing inflammation and relieving pain, has the advantages of quick acting and good curative effect when used for treating oral ulcer, and is used for preventing relapse after healing.

Description

A kind of medicine for the treatment of oral ulcer and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of oral ulcer and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Oral ulcer is a kind of disease that in oral keritonocytes, sickness rate is the highest, common cold, dyspepsia, psychentonia, the gloomy situation such as discomfort all accidentally can cause the generation of this disease, be apt to occur in lip, cheek, lingual margin etc., all can occur at any position of mucosa, but attached gingiva and hard palate are then rare completely in keratinization.Age of onset is generally between 10 ~ 30 years old, and women is more, all can occur throughout the year.This disease has the features such as periodicity, recurrent.At present, western medicine oral ulcer poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of effectively treating oral ulcer in people.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment oral ulcer, thus completes the present invention.

Object of the present invention is just to provide a kind of composition of medicine effectively can treating oral ulcer.

Another object of the present invention just there is provided the preparation method of this composition of medicine.

Medicine of the present invention selects Fructus Arctii, Herba Menthae, Fructus Gardeniae, Herba Taraxaci, Rhizoma Phragmitis, Rhizoma Polygonati Odorati, Radix Rehmanniae Preparata, Cortex Moutan, Fructus Evodiae, Radix Asparagi, Radix Glycyrrhizae, the Rhizoma Anemarrhenae, Herba Pogostemonis, Fructus Forsythiae, Radix Paeoniae Rubra, Fructus Solani melongenae, Flos Rosae Chinensis, Semen Sesami Nigrum, Herba Cistanches, Fructus Jujubae, Radix Codonopsis, Rhizoma Corydalis, catechu, Folium Musae, honeycomb medicine to combine, each efficacy of drugs is made by these drug regimens to produce synergism, thus can the recurrence of rapid, effective treatment oral ulcer.Wherein select Fructus Arctii to be that cool, enter lung, stomach warp, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating, controls cough due to pathogenic wind-heat, laryngopharynx swelling and pain because its nature and flavor are worked hard, macule is not saturating, and rubella is had an itch, carbuncle sore tumefacting virus.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, ward off dirty, the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, have heat clearing away, pathogenic fire purging, the function of removing heat from blood, control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Rhizoma Phragmitis is selected to be that cold, enter lung, stomach warp, has heat clearing away, promotes the production of body fluid, relieving restlessness, and the function of preventing or arresting vomiting controls calentura excessive thirst, gastropyretic vomiting, dysphagic, regurgitation, consumptive lung disease, lung abscess, and separates Fugu ocellatus ichthyotoxin because its nature and flavor are sweet.Select Rhizoma Polygonati Odorati to be that flat, enter lung, stomach warp, has yin nourishing, moisturizes, relieving restlessness, the function of quenching the thirst because its nature and flavor are sweet, control calentura sun wound, cough, excessive thirst, deficient fever, rapid digestion of food is easily hungry, frequent micturition.Select Radix Rehmanniae Preparata to be that tepor, enters liver, kidney channel, have YIN nourishing, and the function of enriching blood controls deficiency of YIN insufficiency of blood, waist knee flaccidity, chronic cough hectic fever due to YIN-deficiency because its nature and flavor are sweet, seminal emission, metrorrhagia, menoxenia, quenches one's thirst, frequency of micturition, deaf, blurred vision.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle ， Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.Select Fructus Evodiae to be because its nature and flavor are worked hard, temperature, poisonous, enter liver, stomach warp, have warming middle-JIAO, pain relieving, regulate the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Select Radix Asparagi to be because its nature and flavor sweetness and bitterness, cold, enter lung, kidney channel, have YIN nourishing, moisturize, lung heat clearing, the function of pathogenic fire reducing, controls fever due to yin deficiency, and cough is spitted blood, and consumptive lung disease, lung abscess, laryngopharynx swelling and pain, quenches one's thirst, constipation.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Herba Pogostemonis is selected to be that tepor, enters lung, spleen, stomach warp, have fast gas because its nature and flavor are pungent, and in, ward off dirty, the function of damp eliminating, cure cold heat-damp in summer, cold and heat, and headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis.Select Fructus Forsythiae to be because its nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, detumescence, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Fructus Solani melongenae is selected to be that enter spleen, stomach, large intestine channel, have heat clearing away, invigorate blood circulation, pain relieving, the function of detumescence, controls discharging fresh blood stool, pyretic toxicity carbuncle sore, skin ulcer because its nature and flavor are sweet, cool.Flos Rosae Chinensis is selected to be that temperature, enter Liver Channel, have promoting blood flow to regulate menstruation, the function of subduing swelling and detoxicating, controls menoxenia, menalgia, traumatic injury, and blood stasis swells and ache, swollen ulcer drug because its nature and flavor are sweet.Select Semen Sesami Nigrum, different name Semen Lini, its nature and flavor are sweet, flat, return liver, kidney, large intestine channel, have invigorating the liver and kidney, benefiting essence-blood, the function that intestine moistening is dry, control and feel dizzy, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.Select Herba Cistanches to be that temperature, enters kidney, large intestine channel, have the kidney invigorating because the sweet acid of its nature and flavor is salty, benefit essence, moisturize, the function of bowel relieving, controls impotence in male, infertilitas feminis, leukorrhagia, metrorrhagia, chills and pain of the waist and kness, blood depletion constipation.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Rhizoma Corydalis is selected to be that temperature, enter liver, stomach warp, invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, the function of pain relieving, controls all pains of trusted subordinate's waist knee joint, menoxenia ， mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury because its nature and flavor are worked hard.Select catechu to be because its nature and flavor are bitter, puckery, be slightly cold, return lung meridian, have the function of removing dampness promoting tissue regeneration and ulcer healing, control ulcer being unable to heal, eczema, aphtha, fall and flutter the pain of injury, traumatic hemorrhage.Select Folium Musae to be because its property slightly sweet flavor, cold, enter conscience two warp, have clearing away heat and promoting diuresis, the function of removing toxic substances, controls calentura, heatstroke, beriberi, and carbuncle detoxifies, and scalds.Nidus Vespae is selected to be because its nature and flavor are sweet, flat, return stomach warp, dispel the wind, counteracting toxic substances, parasite killing, the function of pain relieving, for toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Herba Menthae 5-15 gram of Fructus Gardeniae 3-9 gram of Herba Taraxaci 5-15 gram

Rhizoma Phragmitis 5-15 gram of Rhizoma Polygonati Odorati 10-20 gram of Radix Rehmanniae Preparata 5-15 gram

Cortex Moutan 5-15 gram of Fructus Evodiae 5-15 gram of Radix Asparagi 5-15 gram

Radix Glycyrrhizae 5-15 gram of Rhizoma Anemarrhenae 5-15 gram of Herba Pogostemonis 5-15 gram

Fructus Forsythiae 6-12 gram of Radix Paeoniae Rubra 6-12 gram of Fructus Solani melongenae 8-15 gram

Flos Rosae Chinensis 15-25 gram of Semen Sesami Nigrum 5-15 gram of Herba Cistanches 5-10 gram

Fructus Jujubae 8-15 gram of Radix Codonopsis 4-8 gram of Rhizoma Corydalis 5-15 gram

Catechu 5-15 gram of Folium Musae 15-25 gram of Nidus Vespae 15-22 gram

Fructus Arctii 3-9 gram

Preferable amount is

Fructus Arctii 6 grams of Herba Menthaes 10 grams of Fructus Gardeniaes 6 grams

Herba Taraxaci 10 grams of Rhizoma Phragmitiss 10 grams of Rhizoma Polygonati Odorati 15 grams

Radix Rehmanniae Preparata 10 grams of Cortex Moutans 10 grams of Fructus Evodiaes 10 grams

Radix Asparagi 10 grams of Radix Glycyrrhizaes 10 grams of Rhizoma Anemarrhenaes 10 grams

Herba Pogostemonis 10 grams of Fructus Forsythiaes 9 grams of Radix Paeoniae Rubra 9 grams

Fructus Solani melongenae 10 grams of Flos Rosae Chinensiss 20 grams of Semen Sesami Nigrums 10 grams

Herba Cistanches 6 grams of Fructus Jujubaes 10 grams of Radix Codonopsis 5 grams

10 grams, Rhizoma Corydalis 10 grams of Folium Musae 20 grams of catechu

20 grams, Nidus Vespae

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Fructus Arctii: pick decontamination, sieve removes spare;

2, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;

3, Fructus Gardeniae: get crude drug, removing impurity, the used time smashs to pieces;

4, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;

5, Rhizoma Phragmitis: removing impurity and fibrous root, cutting, dries;

6, Rhizoma Polygonati Odorati: removing impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;

7, Radix Rehmanniae Preparata: get crude drug, steams to surperficial corvinus, takes out, when shining dry to eighty per cant, and section, dry;

8, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;

9, Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;

10, Radix Asparagi: pick decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

11, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;

12, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;

13, Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;

14, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;

15, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;

16, Fructus Solani melongenae: the autumn in summer gathers when fruit is ripe, section, dries;

17, Flos Rosae Chinensis: summer, autumn gather semi-open flower, dry, or dry with low baking temperature;

18, Herba Cistanches: pick clean impurity, clear water soaks, and changes water every day 1-2 times, and as being salty Herba Cistanches, bubble is salinity to the greatest extent, runs through, longitudinal section, dries;

19, Fructus Jujubae: pick clean impurity, enucleation, dry;

20, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;

21, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;

22, catechu: removing impurity, the used time smashs to pieces;

23, Folium Musae: pick decontamination, dries;

24, Nidus Vespae: get crude drug, removing impurity, stripping and slicing, sieve removes chip;

25, Semen Sesami Nigrum: get raw material, removing magazine, sieve removes chip;

Two, prepare

1, the Fructus Arctii of described weight, Herba Menthae, Fructus Gardeniae, Herba Taraxaci, Rhizoma Phragmitis, Rhizoma Polygonati Odorati, Radix Rehmanniae Preparata, Cortex Moutan, Fructus Evodiae, Radix Asparagi, Radix Glycyrrhizae, the Rhizoma Anemarrhenae, Herba Pogostemonis, Fructus Forsythiae, Radix Paeoniae Rubra, Fructus Solani melongenae, Flos Rosae Chinensis, Herba Cistanches, Fructus Jujubae, Radix Codonopsis, Rhizoma Corydalis, catechu, Folium Musae, Nidus Vespae, Semen Sesami Nigrum are decocted with water secondary, add water 8 times amount for the first time, soak after 80 minutes, intense fire decocts boiling 10 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor.

2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 30 minutes, filters to obtain second time decoction liquor.

3, by twice decoction liquor mixing and stirring, be divided into 6 doses and take.

Medicine of the present invention has heat-clearing and toxic substances removing, dissipating blood stasis removing heat from blood, and the function of anti-inflammatory analgetic, is used for the treatment of oral ulcer, short treating period, instant effect, non-relapse after healing, has no side effect.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] Drug therapy oral ulcer of the present invention

1, physical data

Accept out-patient's totally 42 examples for medical treatment.

2, diagnostic criteria

Clinical manifestation

Responsive or occur needle point sample size or slightly large congested district from the beginning of lesion, namely form diameter in a short time at about 2 ~ 4mm, circular or oval, sharply marginated shallow aphtha.Center micro-pits, surface is covered with the faint yellow pseudomembrane of one deck, and around ulcer, mucosa hyperemia is in blush shape, and it is not hard that its end lays one's hand on.Ulcer number is generally about 2 ~ 3.More violent burning pain is had after ulcer.Blush around ulcer, local has an intense pain and can accompany regional glandular enlargement, heating etc.The course of disease be everlasting the moon remaining more than.More afterwards leave over cicatrix, severe patient can formative tissue defect or deformity.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 3 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.

4, efficacy assessment standard

Effective: transference cure, recovery from illness, observes half a year without recidivist;

Take a turn for the better: symptom is clearly better, pain relief, and ulcer surface heals gradually;

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, by Drug therapy oral ulcer patient 42 example of the present invention, effective 38 examples of result, obvious effective rate is 90.48%, and take a turn for the better 3 examples, and improvement rate is 7.14%, and invalid 1 example, total effective rate is 97.62%.

Claims (3)

1. treat a medicine for oral ulcer, its spy is: it is made up of the crude drug in following weight range:

Herba Menthae 5-15 gram of Fructus Gardeniae 3-9 gram of Herba Taraxaci 5-15 gram

Rhizoma Phragmitis 5-15 gram of Rhizoma Polygonati Odorati 10-20 gram of Radix Rehmanniae Preparata 5-15 gram

Cortex Moutan 5-15 gram of Fructus Evodiae 5-15 gram of Radix Asparagi 5-15 gram

Radix Glycyrrhizae 5-15 gram of Rhizoma Anemarrhenae 5-15 gram of Herba Pogostemonis 5-15 gram

Fructus Forsythiae 6-12 gram of Radix Paeoniae Rubra 6-12 gram of Fructus Solani melongenae 8-15 gram

Flos Rosae Chinensis 15-25 gram of Semen Sesami Nigrum 5-15 gram of Herba Cistanches 5-10 gram

Fructus Jujubae 8-15 gram of Radix Codonopsis 4-8 gram of Rhizoma Corydalis 5-15 gram

Catechu 5-15 gram of Folium Musae 15-25 gram of Nidus Vespae 15-22 gram

Fructus Arctii 3-9 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Fructus Arctii 6 grams of Herba Menthaes 10 grams of Fructus Gardeniaes 6 grams

Herba Taraxaci 10 grams of Rhizoma Phragmitiss 10 grams of Rhizoma Polygonati Odorati 15 grams

Radix Rehmanniae Preparata 10 grams of Cortex Moutans 10 grams of Fructus Evodiaes 10 grams

Radix Asparagi 10 grams of Radix Glycyrrhizaes 10 grams of Rhizoma Anemarrhenaes 10 grams

Herba Pogostemonis 10 grams of Fructus Forsythiaes 9 grams of Radix Paeoniae Rubra 9 grams

Fructus Solani melongenae 10 grams of Flos Rosae Chinensiss 20 grams of Semen Sesami Nigrums 10 grams

Herba Cistanches 6 grams of Fructus Jujubaes 10 grams of Radix Codonopsis 5 grams

10 grams, Rhizoma Corydalis 10 grams of Folium Musae 20 grams of catechu

20 grams, Nidus Vespae.

3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:

One, get the raw materials ready

1, Fructus Arctii: pick decontamination, sieve removes spare;

2, Herba Menthae: pick clean impurity, removing undesirable root, first trembles leaf and separately to put down, then stem is sprayed clear water, run through rear cutting, dry, then with leaf and even;

3, Fructus Gardeniae: get crude drug, removing impurity, the used time smashs to pieces;

4, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;

5, Rhizoma Phragmitis: removing impurity and fibrous root, cutting, dries;

6, Rhizoma Polygonati Odorati: removing impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;

7, Radix Rehmanniae Preparata: get crude drug, steams to surperficial corvinus, takes out, when shining dry to eighty per cant, and section, dry;

8, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;

9, Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;

10, Radix Asparagi: pick decontamination, water is cleaned, and moistening is even to inside and outside humidity, cutting, drying;

11, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;

12, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;

13, Herba Pogostemonis: pick decontamination, removing undesirable root and old stem, first taken by leaf and separately put, stem water runs through, and cutting is dried, then with leaf and even;

14, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;

15, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;

16, Fructus Solani melongenae: the autumn in summer gathers when fruit is ripe, section, dries;

17, Flos Rosae Chinensis: summer, autumn gather semi-open flower, dry, or dry with low baking temperature;

18, Herba Cistanches: pick clean impurity, clear water soaks, and changes water every day 1-2 times, and as being salty Herba Cistanches, bubble is salinity to the greatest extent, runs through, longitudinal section, dries;

19, Fructus Jujubae: pick clean impurity, enucleation, dry;

20, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;

21, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;

22, catechu: removing impurity, the used time smashs to pieces;

23, Folium Musae: pick decontamination, dries;

24, Nidus Vespae: get crude drug, removing impurity, stripping and slicing, sieve removes chip;

25, Semen Sesami Nigrum: get raw material, removing magazine, sieve removes chip;

Two, prepare

1, the Fructus Arctii of described weight, Herba Menthae, Fructus Gardeniae, Herba Taraxaci, Rhizoma Phragmitis, Rhizoma Polygonati Odorati, Radix Rehmanniae Preparata, Cortex Moutan, Fructus Evodiae, Radix Asparagi, Radix Glycyrrhizae, the Rhizoma Anemarrhenae, Herba Pogostemonis, Fructus Forsythiae, Radix Paeoniae Rubra, Fructus Solani melongenae, Flos Rosae Chinensis, Herba Cistanches, Fructus Jujubae, Radix Codonopsis, Rhizoma Corydalis, catechu, Folium Musae, Nidus Vespae, Semen Sesami Nigrum are decocted with water secondary, add water 8 times amount for the first time, soak after 80 minutes, intense fire decocts boiling 10 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor;

2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 30 minutes, filters to obtain second time decoction liquor;

3, by twice decoction liquor mixing and stirring, be divided into 6 doses and take.