CN103520530B - Medicament for treating erysipelas and preparation method thereof - Google Patents
Medicament for treating erysipelas and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicament for treating erysipelas and a preparation method thereof. The medicament is prepared mainly from cyathula officinalis, phellodendron amurense, atractylodes lancea, scrophularia ningpoensis, liquorice, Ixeris chinensis, dandelion, Chinese date, angelica, red paeony root and peony bark according to a certain weight proportion. The medicament disclosed by the invention hs functions of clearing heat, removing toxicity, removing stasis, diminishing swelling, expelling toxicity and relieving pain, is used for treating erysipelas, has a short treatment course and a high response speed, has no toxic or side effects and cannot relapse.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of erysipelas and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Erysipelas is that one involves the vasculolymphatic infection of high dermis, and Main Pathogenic Bacteria is A group β Hemolytic streptococcus.Risk factor is below surgical wound or nostril, external auditory meatus, ear-lobe, anus, crack between penis and toe.Any inflammation of skin, especially has and to chap or the inflammation of ulcer is the approach that pathogenic bacterium provide intrusion.Minor abrasions or scratch, damage beyond head, uncleanly ligature of the cord, prophylactic immunization and chronic calf ulcer all may cause this sick.Pathogenic bacterium can hide in intralymphatic, cause recurrence.At present, Western medicine effectively cannot treat erysipelas, and life-time service Western medicine has more side effect, and therefore, people exist very large demand to the Chinese medicine of effectively treating erysipelas.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment erysipelas, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine effectively can treating erysipelas.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Medicine of the present invention selects Radix Cyathulae, Cortex Phellodendri, Rhizoma Atractylodis, Radix Scrophulariae, Radix Glycyrrhizae, Herba Ixeritis chinensis, Herba Taraxaci, Fructus Jujubae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Cortex Moutan, the Radix Astragali, Flos Lonicerae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Radix Bupleuri, Rhizoma Coptidis, Radix Scutellariae, Semen Plantaginis, Semen Phaseoli, Folium Mori, Radix Gentianae, Fructus Chaenomelis, Fructus Liquidambaris, Herba Violae, Folium Isatidis, Radix Isatidis, the Rhizoma Anemarrhenae, Olibanum, Rhizoma Imperatae, Cortex Dictamni, Radix Et Rhizoma Rhei, Rhizoma Alismatis, Radix Sophorae Flavescentis, arnebia medicinal to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of erysipelas.Radix Cyathulae is wherein selected to be that the micro-hardship of bitter in the mouth, nontoxic, enter liver, kidney two warp, dispel the wind, dampness removing, stimulates the menstrual flow, the function of invigorating blood circulation, dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle, stranguria with blood, hematuria, women's amenorrhea ， mass in the abdomen because its nature and flavor are put down.Cortex Phellodendri is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Rhizoma Atractylodis are selected to be that temperature, enters spleen, stomach warp, have spleen invigorating, dampness, resolving depression, ward off dirty function because its nature and flavor are worked hard, control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Select Radix Scrophulariae to be because its nature and flavor are bitter, salty, cool, enter lung, kidney channel, have YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances, control calentura excessive thirst, send out speckle, hectic fever due to YIN-deficiency consumptive fever, sleep night not peaceful, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Herba Ixeritis chinensis is selected to be because it has antidiarrheal, the function of detumescence, treating snakebite, urinary stone.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Fructus Jujubae to be that temperature, enters spleen, stomach warp, have spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid because its nature and flavor are sweet, adjust battalion to defend, separate the function of poison of drug, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea ， Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle ， Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer, flutters damage.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Flos Lonicerae is selected to be because its nature and flavor are sweet, cold, enter lung, stomach warp, have heat clearing away, the function of removing toxic substances, control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Radix Salviae Miltiorrhizae is selected to be that tepor, enters the heart, Liver Channel, have blood circulation and promoting silt, calming heart and tranquilizing mind, evacuation of pus, and the function of pain relieving, controls angina pectoris, menoxenia, dysmenorrhea, and to close, metrorrhagia leukorrhagia ， mass in the abdomen, gathers, abdominal pain due to blood stasis, arthralgia because its nature and flavor are bitter, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Fructus Forsythiae to be because its nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Rhizoma Coptidis is selected to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, have pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, pulmonary tuberculosis, tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Radix Scutellariae is selected to be because its nature and flavor are bitter, cold, enter the heart, lung, gallbladder, large intestine channel, have removing the relative excess fire, except damp and hot, hemostasis, antiabortive function, controls high fever excessive thirst, cough due to lung-heat, damp-heat dysentery, jaundice, pyretic stranguria, tells, is defeated in battle, collapses, leaks, conjunctival congestion and swelling pain, frequent fetal movement, carbuncle furuncle.Semen Plantaginis is selected to be that cold, enter kidney, urinary bladder channel, have diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, and arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view because its nature and flavor are sweet.Semen Phaseoli is selected to be because the sweet acid of its nature and flavor, flat, enter the heart, small intestine meridian, have diuretic to dehumidify, and blood evacuation of pus, the function of subduing swelling and detoxicating, harnesses the river swollen, beriberi, jaundice, and dysentery, has blood in stool, carbuncle.Select Folium Mori to be because its property bitter but sweet flavor, cold, enter lung, Liver Channel, have expelling wind and clearing away heat, the function of cooling blood for improving eyesight, dispelling the wind and dampness pathogens generates heat, headache, and conjunctival congestion is thirsty, cough due to lung-heat, migratory arthralgia, urticaria, lower limb elephatiasis.Select Radix Gentianae to be that cold, enter liver, gallbladder meridian, have eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B because its nature and flavor are bitter, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.Fructus Chaenomelis is selected to be that temperature, enters liver, spleen channel, have suppressing the hyperactive liver and easing the stomach, the function of the relaxing muscles and tendons that dries, and controls convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery because its nature and flavor acid.Fructus Liquidambaris is selected to be that current 12 warps, have dispelling wind and removing obstruction in the collateral, the function of promoting urination to remove dampness, harness the river swollen, distension, amenorrhea, and breast is few, contracture of the limbs because its nature and flavor hardship is flat.Select Herba Violae to be that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because its nature and flavor bitter, acrid, cold, the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Folium Isatidis is selected to be because its nature and flavor are bitter, cold, enter liver, the heart, stomach warp, have heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Select Radix Isatidis to be because its nature and flavor are bitter, cold, enter liver, stomach blood system, have heat clearing away, removing toxic substances, the function of removing heat from blood, controls influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, and pyretic toxicity sends out speckle, and coma tells nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash.The Rhizoma Anemarrhenae is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Olibanum to be that temperature, enters the heart, liver, spleen channel, have regulating qi and activating blood, analgesic therapy because its nature and flavor are worked hard, chase after the function of poison, control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select Rhizoma Imperatae to be sweet because of its nature and flavor, cold, enter lung, stomach, small intestine meridian, have removing heat from blood, hemostasis, heat clearing away, the function of diuresis, controls calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Cortex Dictamni is selected to be because its nature and flavor are bitter, salty, cold, enter spleen, stomach warp, dispel the wind, dampness, heat clearing away, the function of removing toxic substances, control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.Radix Et Rhizoma Rhei is selected to be that enter stomach, large intestine, liver footpath, have the poison that purges heat, removing mass is stagnant because its nature and flavor are bitter, cold, the function of clots absorbing blood, control excess-heat constipation, delirium is gone mad, food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia, spits blood, epistaxis, YANG jaundice, edema, stranguria with turbid discharge, urinates red, carbuncle and ulcer toxic swelling, furuncle, burn.Select Rhizoma Alismatis to be that cold, enter urinary bladder channel, have diuretic, eliminating dampness by diuresis, the function expelled the heat-evil, controls dysuria because its nature and flavor are sweet, edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Radix Sophorae Flavescentis is selected to be that cold, enter liver, kidney, large intestine, small intestine meridian, have heat clearing away, dampness, the function of parasite killing, controls toxic-heat and blood stasis because its nature and flavor are bitter, discharging fresh blood stool, jaundice, leucorrhea with red and white discharge, infantile pneumonia, infantile malnutrition, acute tonsillitis, anal fistula, proctoptosis, skin pruritus, erosion of vulva pruritus due to damp pathogen, scrofula, scalds.Radix Arnebiae (Radix Lithospermi) is selected to be because its nature and flavor earnestly, are trembled with fear, entered percardium, Liver Channel, have removing heat from blood, invigorate blood circulation, the function of heat-clearing and toxic substances removing, control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, dysentery, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Radix Cyathulae 10-20 gram of Cortex Phellodendri 10-20 gram of Rhizoma Atractylodis 5-15 gram
Radix Scrophulariae 5-15 gram of Radix Glycyrrhizae 5-15 Keshan gutweed 10-20 gram
Herba Taraxaci 10-20 gram of Fructus Jujubae 4-10 gram of Radix Angelicae Sinensis 10-20 gram
Radix Paeoniae Rubra 10-20 gram of Cortex Moutan 10-20 gram of Radix Astragali 15-25 gram
Flos Lonicerae 10-20 gram of Radix Salviae Miltiorrhizae 10-20 gram of Fructus Forsythiae 5-15 gram
Radix Bupleuri 10-20 gram of Rhizoma Coptidis 2-5 gram of Radix Scutellariae 5-15 gram
Semen Plantaginis 5-15 gram of Semen Phaseoli 5-15 gram of Folium Mori 5-15 gram
Radix Gentianae 3-10 gram of Fructus Chaenomelis 5-15 gram of Fructus Liquidambaris 10-20 gram
Herba Violae 5-15 gram of Folium Isatidis 10-20 gram of Radix Isatidis 5-15 gram
Rhizoma Anemarrhenae 5-15 gram of Olibanum 10-15 gram of Rhizoma Imperatae 10-15 gram
Cortex Dictamni 5-15 gram of Radix Et Rhizoma Rhei 5-15 gram of Rhizoma Alismatis 5-15 gram
Radix Sophorae Flavescentis 10-20 gram of Radix Arnebiae (Radix Lithospermi) 5-15 gram.
Preferable amount is
Radix Cyathulae 15 grams of Cortex Phellodendris 15 grams of Rhizoma Atractylodis 10 grams
Radix Scrophulariae 10 grams of Radix Glycyrrhizae 10 Keshan gutweeds 15 grams
Herba Taraxaci 15 grams of Fructus Jujubaes 6 grams of Radix Angelicae Sinensis 15 grams
Radix Paeoniae Rubra 15 grams of Cortex Moutans 15 grams of Radixs Astragali 20 grams
Flos Lonicerae 15 grams of Radix Salviae Miltiorrhizaes 15 grams of Fructus Forsythiaes 10 grams
Radix Bupleuri 15 grams of Rhizoma Coptidis 3 grams of Radix Scutellariaes 10 grams
10 grams, Semen Plantaginis 10 grams of Semen Phaseolis 10 grams of Folium Mori
Radix Gentianae 5 grams of Fructus Chaenomeliss 10 grams of Fructus Liquidambaris 15 grams
Herba Violae 10 grams of Folium Isatidiss 15 grams of Radix Isatidis 10 grams
The Rhizoma Anemarrhenae 10 grams of Olibanums 12 grams of Rhizoma Imperataes 12 grams
Cortex Dictamni 10 grams of Radix Et Rhizoma Rhei 10 grams of Rhizoma Alismatis 10 grams
Radix Sophorae Flavescentis 15 grams of Radix Arnebiae (Radix Lithospermi)s 10 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Cyathulae: pick decontamination, dries;
2, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
3, Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
4, Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;
5, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
6, Herba Ixeritis chinensis: pick decontamination, cleans earth;
7, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
8, Fructus Jujubae: pick clean impurity, dry;
9, Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;
10, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
11, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
12, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
13, Flos Lonicerae: sieve removes silt, picks clean impurity;
14, Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
15, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
16, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
17, Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
18, Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and section, dries;
19, Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
20, Semen Phaseoli: get crude drug, removing impurity, the used time smashs to pieces;
21, Folium Mori: pick decontamination, rub with the hands broken, winnow with a dustpan destemming, and sieve removes spare;
22, Radix Gentianae: pick decontamination, removes residual stem, cleans, runs through rear cutting, dry;
23, Fructus Chaenomelis: clear water is cleaned, and slightly soaks, moistening, to thoroughly, is put in food steamer and is cooked, take advantage of fervent sheet, weather exposure, with by the red atropurpureus that turns for degree;
24, Fructus Liquidambaris: removing impurity, cleans, dries;
25, Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
26, Folium Isatidis: pick decontamination and dead leaf, cleans, slightly moistens, cutting, dry;
27, Radix Isatidis: pick clean impurity, cleans, runs through, and section, dries;
28, the Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
29, Olibanum: pick the sub-impurity of shakeout;
30, Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;
31, Cortex Dictamni: pick clean impurity, removing rough bark, cleans, slightly moistens, and section, dries;
32, Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;
33, Rhizoma Alismatis: pick decontamination, size stepping, be soaked in water to eighty per cant thoroughly, pull out, shine cool, moistening is even to inside and outside humidity, and section, dries;
34, Radix Sophorae Flavescentis: pick clean impurity, removes residual stem, cleans earth, is soaked in water, pulls out, run through, and section, dries;
35, Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries.
Two, prepare
1, by the Radix Cyathulae of described weight, Cortex Phellodendri, Rhizoma Atractylodis, Radix Scrophulariae, Radix Glycyrrhizae, Herba Ixeritis chinensis, Herba Taraxaci, Fructus Jujubae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Cortex Moutan, the Radix Astragali, Flos Lonicerae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Radix Bupleuri, Rhizoma Coptidis, Radix Scutellariae, Semen Plantaginis, Semen Phaseoli, Folium Mori, Radix Gentianae, Fructus Chaenomelis, Fructus Liquidambaris, Herba Violae, Folium Isatidis, Radix Isatidis, the Rhizoma Anemarrhenae, Olibanum, Rhizoma Imperatae, Cortex Dictamni, Radix Et Rhizoma Rhei, Rhizoma Alismatis, Radix Sophorae Flavescentis, arnebia medicinal adds 10 times of water gagings and soaks, soak after 200 minutes, intense fire decocts boiling 25 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor.
2, add water the medicinal residues of filtration 6 times amount, and intense fire decocts boiling 10 minutes, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor.
3, merge twice decoction liquor, mix homogeneously and get final product, decoction liquor be divided into 6 doses to take.
Medicine of the present invention has heat-clearing and toxic substances removing, eliminating stagnation, detumescence, evacuation of pus, and effect of pain relieving, is used for the treatment of erysipelas, short treating period, instant effect, non-relapse after healing, has no side effect.
Detailed description of the invention
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, and every day, secondary, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] Drug therapy erysipelas of the present invention
1, physical data
Accept out-patient's totally 155 examples for medical treatment.
2, diagnostic criteria
Advanced symptoms has unexpected heating, shiver with cold, it is nauseating not accommodate.There is erythema in a few hours, and Progressive symmetric erythrokeratodermia expands after 1 day, boundary clear.Affected part Pi Wengao, anxiety, and occur scleroma and nonpitting edema, affected area has tenderness, causalgia, commonly closely defends lymphadenectasis, companion or do not accompany lymphadenitis.Also the hemorrhagic necrosis of pustule, vesicle or small size can be there is.Be apt to occur in shank, facial area.
The recurrence of erysipelas can cause persistence regional nodes edema, and end product is permanent hypertrophica fibrosis, is called elephantiasis nostras.Patients with mastocarcinoma armpit lymph node dissection is postoperative due to lymphostasis, also easily repeatedly suffers from erysipelas.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 7 days, is a course for the treatment of, takes 4 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: erysipelas transference cure, body constitution recovers normal, observes half a year without recidivist;
Take a turn for the better: erysipelas symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy erysipelas patient 155 example of the present invention, effective 148 examples of result, obvious effective rate is 95.48%, and take a turn for the better 5 examples, and improvement rate is 3.23%, and invalid 2 examples, total effective rate is 98.71%.
Claims (3)
1. treat a medicine for erysipelas, it is characterized in that: it is made up of the crude drug in following weight range:
Radix Cyathulae 10-20 gram of Cortex Phellodendri 10-20 gram of Rhizoma Atractylodis 5-15 gram
Radix Scrophulariae 5-15 gram of Radix Glycyrrhizae 5-15 Keshan gutweed 10-20 gram
Herba Taraxaci 10-20 gram of Fructus Jujubae 4-10 gram of Radix Angelicae Sinensis 10-20 gram
Radix Paeoniae Rubra 10-20 gram of Cortex Moutan 10-20 gram of Radix Astragali 15-25 gram
Flos Lonicerae 10-20 gram of Radix Salviae Miltiorrhizae 10-20 gram of Fructus Forsythiae 5-15 gram
Radix Bupleuri 10-20 gram of Rhizoma Coptidis 2-5 gram of Radix Scutellariae 5-15 gram
Semen Plantaginis 5-15 gram of Semen Phaseoli 5-15 gram of Folium Mori 5-15 gram
Radix Gentianae 3-10 gram of Fructus Chaenomelis 5-15 gram of Fructus Liquidambaris 10-20 gram
Herba Violae 5-15 gram of Folium Isatidis 10-20 gram of Radix Isatidis 5-15 gram
Rhizoma Anemarrhenae 5-15 gram of Olibanum 10-15 gram of Rhizoma Imperatae 10-15 gram
Cortex Dictamni 5-15 gram of Radix Et Rhizoma Rhei 5-15 gram of Rhizoma Alismatis 5-15 gram
Radix Sophorae Flavescentis 10-20 gram of Radix Arnebiae (Radix Lithospermi) 5-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Cyathulae 15 grams of Cortex Phellodendris 15 grams of Rhizoma Atractylodis 10 grams
Radix Scrophulariae 10 grams of Radix Glycyrrhizae 10 Keshan gutweeds 15 grams
Herba Taraxaci 15 grams of Fructus Jujubaes 6 grams of Radix Angelicae Sinensis 15 grams
Radix Paeoniae Rubra 15 grams of Cortex Moutans 15 grams of Radixs Astragali 20 grams
Flos Lonicerae 15 grams of Radix Salviae Miltiorrhizaes 15 grams of Fructus Forsythiaes 10 grams
Radix Bupleuri 15 grams of Rhizoma Coptidis 3 grams of Radix Scutellariaes 10 grams
10 grams, Semen Plantaginis 10 grams of Semen Phaseolis 10 grams of Folium Mori
Radix Gentianae 5 grams of Fructus Chaenomeliss 10 grams of Fructus Liquidambaris 15 grams
Herba Violae 10 grams of Folium Isatidiss 15 grams of Radix Isatidis 10 grams
The Rhizoma Anemarrhenae 10 grams of Olibanums 12 grams of Rhizoma Imperataes 12 grams
Cortex Dictamni 10 grams of Radix Et Rhizoma Rhei 10 grams of Rhizoma Alismatis 10 grams
Radix Sophorae Flavescentis 15 grams of Radix Arnebiae (Radix Lithospermi)s 10 grams.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Radix Cyathulae: pick decontamination, dries;
(2) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
(3) Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
(4) Radix Scrophulariae: pick clean impurity, except removing LU, clean and run through, section, dries;
(5) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, runs through, section, airing;
(6) Herba Ixeritis chinensis: pick decontamination, cleans earth;
(7) Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
(8) Fructus Jujubae: pick clean impurity, dry;
(9) Radix Angelicae Sinensis: pick decontamination, cleans, moistening, and slightly dry in the air when being suitable for inside and outside humidity, section is dried;
(10) Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
(11) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(12) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
(13) Flos Lonicerae: sieve removes silt, picks clean impurity;
(14) Radix Salviae Miltiorrhizae: pick clean impurity, removing rhizome, cleans, pulls out, run through rear section, dry;
(15) Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
(16) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear timely section, dry immediately;
(17) Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
(18) Radix Scutellariae: pick decontamination, removes residual stem, infiltrates or put in boiled water slightly to soak to pull out with cold water, and section, dries;
(19) Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
(20) Semen Phaseoli: get crude drug, removing impurity, the used time smashs to pieces;
(21) Folium Mori: pick decontamination, rub with the hands broken, winnow with a dustpan destemming, and sieve removes spare;
(22) Radix Gentianae: pick decontamination, removes residual stem, cleans, runs through rear cutting, dry;
(23) Fructus Chaenomelis: clear water is cleaned, and slightly soaks, moistening, to thoroughly, is put in food steamer and is cooked, take advantage of fervent sheet, weather exposure, with by the red atropurpureus that turns for degree;
(24) Fructus Liquidambaris: removing impurity, cleans, dries;
(25) Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
(26) Folium Isatidis: pick decontamination and dead leaf, cleans, slightly moistens, cutting, dry;
(27) Radix Isatidis: pick clean impurity, cleans, runs through, and section, dries;
(28) Rhizoma Anemarrhenae: pick clean impurity, hit with water and wash, pull out, soften, section is dried;
(29) Olibanum: pick the sub-impurity of shakeout;
(30) Rhizoma Imperatae: pick clean impurity, clean, micro-profit, cutting, dries, clean chip of winnowing with a dustpan;
(31) Cortex Dictamni: pick clean impurity, removing rough bark, cleans, slightly moistens, and section, dries;
(32) Radix Et Rhizoma Rhei: pick clean impurity, size stepping, stews to moisten to inside and outside humidity even, cuts into slices or is cut into small pieces, dries;
(33) Rhizoma Alismatis: pick decontamination, size stepping, be soaked in water to eighty per cant thoroughly, pull out, shine cool, moistening is even to inside and outside humidity, and section, dries;
(34) Radix Sophorae Flavescentis: pick clean impurity, removes residual stem, cleans earth, is soaked in water, pulls out, run through, and section, dries;
(35) Radix Arnebiae (Radix Lithospermi): clean, run through, section, dries;
(2) prepare
(1) by the Radix Cyathulae of described weight, Cortex Phellodendri, Rhizoma Atractylodis, Radix Scrophulariae, Radix Glycyrrhizae, Herba Ixeritis chinensis, Herba Taraxaci, Fructus Jujubae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Cortex Moutan, the Radix Astragali, Flos Lonicerae, Radix Salviae Miltiorrhizae, Fructus Forsythiae, Radix Bupleuri, Rhizoma Coptidis, Radix Scutellariae, Semen Plantaginis, Semen Phaseoli, Folium Mori, Radix Gentianae, Fructus Chaenomelis, Fructus Liquidambaris, Herba Violae, Folium Isatidis, Radix Isatidis, the Rhizoma Anemarrhenae, Olibanum, Rhizoma Imperatae, Cortex Dictamni, Radix Et Rhizoma Rhei, Rhizoma Alismatis, Radix Sophorae Flavescentis, arnebia medicinal adds 10 times of water gagings and soaks, soak after 200 minutes, intense fire decocts boiling 25 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor,
(2) add water the medicinal residues of filtration 6 times amount, and intense fire decocts boiling 10 minutes, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) twice decoction liquor is merged, mix homogeneously and get final product.
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| CN103877286A (en) * | 2014-03-11 | 2014-06-25 | 四川金堂海纳生物医药技术研究所 | Orally taken medicine for treating erysipelas and preparation method thereof |
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| CN112972559B (en) * | 2021-03-30 | 2022-10-28 | 上海市第七人民医院(上海中医药大学附属第七人民医院) | Traditional Chinese medicine composition and traditional Chinese medicine mixture for treating bone and soft tissue suppurative inflammation |
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| CN101095821A (en) * | 2007-07-05 | 2008-01-02 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating diabetes erysipelas |
| CN102370799A (en) * | 2010-08-19 | 2012-03-14 | 王雅欣 | Traditional Chinese medicine decoction for treating head erysipelas |
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| CN101095821A (en) * | 2007-07-05 | 2008-01-02 | 北京艺信堂医药研究所 | Chinese traditional medicine preparations for treating diabetes erysipelas |
| CN102370799A (en) * | 2010-08-19 | 2012-03-14 | 王雅欣 | Traditional Chinese medicine decoction for treating head erysipelas |
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| Title |
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| 234首丹毒内服方剂的用药规律分析;周园龙等;《江苏中医药》;20120930;第44卷(第9期);64-66 * |
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