CN105343490A - Medicine for treating haemorrhoids and preparation method of medicine - Google Patents
Medicine for treating haemorrhoids and preparation method of medicine Download PDFInfo
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- CN105343490A CN105343490A CN201510985244.4A CN201510985244A CN105343490A CN 105343490 A CN105343490 A CN 105343490A CN 201510985244 A CN201510985244 A CN 201510985244A CN 105343490 A CN105343490 A CN 105343490A
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Abstract
The invention discloses a medicine for treating haemorrhoids and a preparation method of the medicine. The medicine is mainly prepared from flos sophorae, Chinese angelica, honeysuckle, Chinese honeylocust spine, golden thread, dandelion, astragalus membranaceus, garden burnet roots, oriental waterplantain rhizomes, safflower, liquorice, medulla junci, weeping forsythiae capsule, swordlike atractylodes rhizomes, thunberg fritillary bulb, bitter orange, rehmannia roots, areca seeds, incised notopterygium rhizomes, desertliving cistanche, diverse wormwood herb, dahurian angelica roots, tea leaves, red paeony roots, moutan bark and szechuan lovage rhizomes by weight. The medicine has the functions of kidney tonification, essence enrichment, blood replenishment and harmonizing, qi regulation, stagnancy removal, heat clearing, detoxification, dryness moistening, intestine lubrication, exterior consolidation and spleen invigorating, takes effect quickly when used for treating haemorrhoids and has a good curative effect, and haemorrhoids do not relapse.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of hemorrhoid and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Hemorrhoid are the vein groups formed with the venous plexus congestion under anal canal skin, expansion and flexing under distal rectal mucosa.The traditional Chinese medical science thinks hemorrhoid and qi depression to blood stasis, and wind hinders intestinal network, sinking of QI due to deficiency of the spleen, and damp invasion of lower energizer is relevant.Because western medicine side effect is large, therefore there is great demand to the Chinese medicine of effectively treating hemorrhoid in people, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effectively treatment hemorrhoid, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of effective treatment hemorrhoid.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Flos Sophorae, Radix Angelicae Sinensis, Flos Lonicerae, Spina Gleditsiae, Rhizoma Coptidis, Herba Taraxaci, the Radix Astragali, Radix Sanguisorbae, Rhizoma Alismatis, Flos Carthami, Radix Glycyrrhizae, Medulla Junci, Fructus Forsythiae, Rhizoma Atractylodis, Bulbus Fritillariae Thunbergii, Fructus Aurantii, Radix Rehmanniae, Semen Arecae, Rhizoma Et Radix Notopterygii, Herba Cistanches, Herba Artemisiae Anomalae, the Radix Angelicae Dahuricae, Folium Camelliae sinensis, Radix Paeoniae Rubra, Cortex Moutan, Rhizoma Chuanxiong, Massa Medicata Fermentata, Cortex Phellodendri, Rhizoma Paridis to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat hemorrhoid.Wherein, Flos Sophorae is selected to be that cool, enter liver, large intestine channel, have heat clearing away, removing heat from blood, the function of hemostasis, controls discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, epistaxis because its nature and flavor are bitter, under dysentery with red and white feces, wind heat conjunctival congestion, skin sore, and for prevention of stroke.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Spina Gleditsiae to be that temperature, searches wind, draw out pus by applying a plaster to the affected part because its nature and flavor are pungent, detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Rhizoma Coptidis is selected to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, have pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, pulmonary tuberculosis, tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Radix Sanguisorbae is selected to be because of its nature and flavor picric acid, to tremble with fear.Enter liver, large intestine channel.Cooling blood for hemostasis, heat-clearing and toxic substances removing.Control haematemesis, epistaxis, dysentery, collapse, hemorrhoidal hamorrhage, anal fistula, carbuncle, eczema, incised wound, burn.Select Rhizoma Alismatis to be that cold, enter urinary bladder channel, have diuretic, eliminating dampness by diuresis, the function expelled the heat-evil, controls dysuria because its nature and flavor are sweet, edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Medulla Junci to be because its property slightly sweet flavor, cold, enter the heart, lung, small intestine meridian, have clearing heart fire, the function of inducing diuresis for treating stranguria syndrome, controls gonorrhea, edema, dysuria, jaundice due to damp-heat, dysphoria and insomnia, the nocturnal fretfulness in infants, sore throat, wound.Select Fructus Forsythiae to be because its nature and flavor are bitter, cool, enter the heart, liver, gallbladder meridian, have heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, controls warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.Rhizoma Atractylodis are selected to be that temperature, enters spleen, stomach warp, have spleen invigorating, dampness, resolving depression, ward off dirty function because its nature and flavor are worked hard, control wet Sheng and be stranded spleen, asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting, has loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens is caught a cold, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Bulbus Fritillariae Thunbergii is selected to be that be slightly cold, return lung, heart channel, have heat clearing away eliminating stagnation, the function of preventing phlegm from forming and stopping coughing, controls wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore, and ambition is gloomy because its nature and flavor are bitter.Fructus Aurantii is selected to be because its nature and flavor toil, cool, enter lung, spleen, large intestine channel, have dispelling the stagnated QI, row expectorant, the function of removing food stagnancy, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Radix Rehmanniae to be that cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, the function of promoting the production of body fluid, and controls calentura excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, and interior-heat is quenched one's thirst because its nature and flavor are sweet, spit blood, epistaxis, sends out speckle dermexanthesis.Select Semen Arecae to be because its nature and flavor toil, temperature, enters spleen, stomach, large intestine channel, has parasite killing, removing mass, the therapeutic method to keep the adverse QI flowing downwards, the function of row water, control malnutrition due to parasitic infestation, dyspepsia, abdominal distention, and heavy after dysentery, malaria, edema, beriberi, accumulation of phlegm in the hypochondrium , Disorder ties.Rhizoma Et Radix Notopterygii is selected to be that temperature, enter bladder, kidney channel, have loose exterior cold, wind-damp dispelling, the function in sharp joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore because its nature and flavor are worked hard.Select Herba Cistanches to be that temperature, enters kidney, large intestine channel, have the kidney invigorating because the sweet acid of its nature and flavor is salty, benefit essence, moisturize, the function of bowel relieving, controls impotence in male, infertilitas feminis, leukorrhagia, metrorrhagia, chills and pain of the waist and kness, blood depletion constipation.Select Herba Artemisiae Anomalae to be because its nature and flavor are bitter, temperature, enter the heart, spleen channel, have removing blood stasis to stimulate the menstrual flow, the function of healing up sore and subduing swelling, controls amenorrhea and mass in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, Yong Du burning swelling.Select the Radix Angelicae Dahuricae to be that temperature, enters lung, spleen, stomach warp, dispel the wind, dampness because its nature and flavor are pungent, detumescence, the function of pain relieving, controls headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.Select Folium Camelliae sinensis to be that cool, GUIXIN lung stomach warp, has and reduce phlegm, help digestion because its property bitter but sweet flavor, the function of diuresis removing toxic substances, control headache blurred vision, food stagnation expectorant is stagnant, malaria, dysentery.Select Radix Paeoniae Rubra to be because its nature and flavor are bitter, be slightly cold, return Liver Channel, have clearing away heat and cooling blood, the function of eliminating stasis to stop pain, control warm poison and go mad, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea , Epilepsy abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Fructus Cannabis is selected to be that flat, enter spleen, stomach, large intestine channel, have and moisturize, laxation, treating stranguria, the function of invigorating blood circulation, control dryness of the intestine constipation, quench one's thirst, pyretic stranguria, migratory arthralgia, dysentery, menoxenia, scabies, tinea is insane because its nature and flavor are sweet.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Rhizoma Chuanxiong to be that temperature, enters liver, gallbladder meridian, have activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, the function of promoting blood circulation and stopping pain, control air-cooled headache and revolve dizzy because its nature and flavor are pungent, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.Select Massa Medicata Fermentata to be because its nature and flavor sweet, acrid, warm, enter upright stone tablet, stomach warp, have invigorating the spleen and regulating the stomach, the function helped digestion in adjusting, controls retention of food and drink, feeling of stuffiness in chest abdominal distention, vomiting dysentery, and postnatal blood stasis is suffered from abdominal pain, and children's's enlarged abdomen heavily fortified point is long-pending.Cortex Phellodendri is selected to be because its nature and flavor are bitter, cold, enter lung, stomach, kidney channel, have nourishing YIN to lower pathogenic fire, moisturize the function of laxation, control dysphoria with smothery sensation and quench one's thirst, hectic fever due to YIN-deficiency consumptive fever, cough due to lung-heat, constipation due to dry stool, dysuria.Select Rhizoma Paridis to be because its nature and flavor are bitter, be slightly cold, slightly poisonous, return Liver Channel, have heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutter the pain of injury, convulsion with spasms.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Flos Sophorae 5-15 gram, Radix Angelicae Sinensis 15-25 gram, Flos Lonicerae 10-20 gram, Spina Gleditsiae 15-25 gram, Rhizoma Coptidis 10-20 gram, Herba Taraxaci 10-20 gram, Radix Astragali 15-20 gram, Radix Sanguisorbae 10-15 gram, Rhizoma Alismatis 5-15 gram, Flos Carthami 5-15 gram, Radix Glycyrrhizae 10-20 gram, Medulla Junci 10-15 gram, Fructus Forsythiae 10-20 gram, Rhizoma Atractylodis 10-15 gram, Bulbus Fritillariae Thunbergii 5-15 gram, Fructus Aurantii 5-15 gram, Radix Rehmanniae 10-15 gram, Semen Arecae 10-15 gram, Rhizoma Et Radix Notopterygii 5-15 gram, Herba Cistanches 10-20 gram, Herba Artemisiae Anomalae 5-15 gram, Radix Angelicae Dahuricae 5-15 gram, Folium Camelliae sinensis 5-10 gram, Radix Paeoniae Rubra 5-15 gram, Fructus Cannabis 10-20 gram, Cortex Moutan 10-20 gram, Rhizoma Chuanxiong 10-15 gram, Massa Medicata Fermentata 5-15 gram, Cortex Phellodendri 10-15 gram, Rhizoma Paridis 5-15 gram.
Be preferably:
10 grams, Flos Sophorae, Radix Angelicae Sinensis 20 grams, Flos Lonicerae 15 grams, Spina Gleditsiae 20 grams, Rhizoma Coptidis 15 grams, Herba Taraxaci 15 grams, the Radix Astragali 18 grams, Radix Sanguisorbae 12 grams, Rhizoma Alismatis 10 grams, 10 grams, Flos Carthami, 15 grams, Radix Glycyrrhizae, Medulla Junci 12 grams, Fructus Forsythiae 15 grams, Rhizoma Atractylodis 12 grams, Bulbus Fritillariae Thunbergii 10 grams, Fructus Aurantii 10 grams, Radix Rehmanniae 12 grams, Semen Arecae 12 grams, Rhizoma Et Radix Notopterygii 10 grams, Herba Cistanches 15 grams, Herba Artemisiae Anomalae 10 grams, the Radix Angelicae Dahuricae 10 grams, Folium Camelliae sinensis 8 grams, Radix Paeoniae Rubra 10 grams, Fructus Cannabis 15 grams, Cortex Moutan 15 grams, Rhizoma Chuanxiong 12 grams, Massa Medicata Fermentata 10 grams, Cortex Phellodendri 12 grams, Rhizoma Paridis 10 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
2, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
3, Flos Lonicerae: sieve removes silt, picks clean impurity;
4, Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;
5, Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
6, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
7, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
8, Radix Sanguisorbae: pick decontamination, washes, and slightly soaks, and runs through, and is cut into sheet, dries;
9, Rhizoma Alismatis: pick decontamination, size stepping, be soaked in water to eighty per cant thoroughly, pull out, shine cool, moistening is even to inside and outside humidity, and section, dries;
10, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
11, Radix Glycyrrhizae: extracting liquorice sheet, adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed, and put in pot and fry to deepening yellow with slow fire, till tack-free, taking-up cools, 100 jin, every Radix Glycyrrhizae, with cooked Mel 25-30 jin;
12, Medulla Junci: get Medulla Junci and put in pot, above cover the pot that a bore is smaller, paste with blank sheet of paper, two pots of junctions, use brine sludge sealing, do not make to lose heart, and being calcined to blank sheet of paper is that coke yellow is ceased fire, and takes out after cooling completely;
13, Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
14, Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
15, Bulbus Fritillariae Thunbergii: removing impurity, size stepping, cleans, runs through, cut sheet, dry, and sieve removes chip, or smashes;
16, Fructus Aurantii: removing flesh, core, edulcoration, slightly soaks, and pulls out, softens, and till pinching doubling with hands, section, dries;
17, Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
18, Semen Arecae: pick decontamination, soaks with clear water, changes water, to soaking, pick up by temperature situation, and section, dries;
19, Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
20, Herba Cistanches: pick clean impurity, clear water soaks, and changes water every day 1-2 times, and as being salty Herba Cistanches, bubble is salinity to the greatest extent, runs through, longitudinal section, dries;
21, Herba Artemisiae Anomalae: pick clean impurity, remove root, uses water edulcoration, slightly soaks, cutting, dry;
22, the Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
23, Folium Camelliae sinensis: after fresh leaf gathers, through completing, knead, green tea is made in drying;
24, Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
25, Fructus Cannabis: pick decontamination and residual shell, get clean core;
26, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
27, Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
28, Massa Medicata Fermentata: get wheat bran and sprinkle evenly in hot pot, cigarette of having waited, pours into Massa Medicata Fermentata, fry to yellow, take out, sieve removes wheat bran, cools;
29, Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
30, Rhizoma Paridis: removing fibrous root, cleaning, drying;
Two, prepare
1, the Flos Sophorae cooked, Radix Angelicae Sinensis, Flos Lonicerae, Spina Gleditsiae, Rhizoma Coptidis, Herba Taraxaci, the Radix Astragali, Radix Sanguisorbae, Rhizoma Alismatis, Flos Carthami, Radix Glycyrrhizae, Medulla Junci, Fructus Forsythiae, Rhizoma Atractylodis, Bulbus Fritillariae Thunbergii, Fructus Aurantii, Radix Rehmanniae, Semen Arecae, Rhizoma Et Radix Notopterygii, Herba Cistanches, Herba Artemisiae Anomalae, the Radix Angelicae Dahuricae, Folium Camelliae sinensis, Radix Paeoniae Rubra, Fructus Cannabis, Cortex Moutan, Rhizoma Chuanxiong, Massa Medicata Fermentata, Cortex Phellodendri, Rhizoma Paridis are put into decocting container, add water 8 times amount for the first time, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
2, the medicinal residues of filtration are added 6 times amount, intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
3, by twice decoction liquor mixing and stirring, 4 doses are divided into take.
In prescription, Herba Cistanches has the kidney invigorating, benefit essence, and moisturize, the function of bowel relieving is monarch drug; Fructus Cannabis is moisturized, laxation, treating stranguria, invigorates blood circulation; Radix Angelicae Sinensis has benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes the function of laxation, and the two is ministerial drug, three taste medicines play the kidney invigorating jointly, and benefit essence, enriches blood, invigorate blood circulation, moisturize, the effect of laxation, treatment hemorrhoid effect is comprehensive, and with the kidney invigorating, and blood, moisturizing is that master can be effected a permanent cure, and the Radix Astragali is useful defends consolidating superficial resistance, inducing diuresis to remove edema, poison holding, the function of granulation promoting is adjuvant drug, and Rhizoma Atractylodis have spleen invigorating, dampness, resolving depression, wards off dirty function for making medicine, is take stopgap measures with all medicines of remainder.
Medicine of the present invention has the kidney invigorating and essence nourishing, benefiting blood and regulating blood circulation, pleasant intestinal stasis relieving, and heat clearing away toxin expelling, moisturizes laxation, and benefit defends consolidating superficial resistance, and the function of spleen invigorating, is used for the treatment of hemorrhoid, short treating period, instant effect, non-relapse after healing.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Taking medicinal liquid super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept hemorrhoid out-patient totally 27 examples for medical treatment.
2, diagnostic criteria
Classical symptom is for having blood in stool, the character of having blood in stool can be painless, intermittent, blood after an action of the bowels, just bleed time or blood is with by toilet paper, constipation, to drink or irritable food postemphasis of taking food, pure internal hemorrhoid is without pain only falling inflation sense, can be hemorrhage, be developed to prolapsus, when merging thrombosis, incarceration, infection, just occur pain; . external hemorrhoid, at ordinary times without characteristic symptom, can have the symptom such as swelling, pain when there is thrombosis and inflammation.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day early, evening respectively takes 1 time, within 7 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: hemorrhoid symptom disappears, body constitution recovers normal, recovery from illness;
Take a turn for the better: patient has blood in stool, anus swelling, and the phenomenon of pain and falling inflation sense alleviates, and hemorrhoid symptom is clearly better, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy hemorrhoid patients 27 example of the present invention, effective 21 examples of result, obvious effective rate is 77.78%, and take a turn for the better 5 examples, and improvement rate is 18.51%, and invalid 1 example, total effective rate is 96.29%.
Claims (3)
1. treat a medicine for hemorrhoid, it is characterized in that: it is made up of the crude drug in following weight range:
Flos Sophorae 5-15 gram, Radix Angelicae Sinensis 15-25 gram, Flos Lonicerae 10-20 gram, Spina Gleditsiae 15-25 gram, Rhizoma Coptidis 10-20 gram, Herba Taraxaci 10-20 gram, Radix Astragali 15-20 gram, Radix Sanguisorbae 10-15 gram, Rhizoma Alismatis 5-15 gram, Flos Carthami 5-15 gram, Radix Glycyrrhizae 10-20 gram, Medulla Junci 10-15 gram, Fructus Forsythiae 10-20 gram, Rhizoma Atractylodis 10-15 gram, Bulbus Fritillariae Thunbergii 5-15 gram, Fructus Aurantii 5-15 gram, Radix Rehmanniae 10-15 gram, Semen Arecae 10-15 gram, Rhizoma Et Radix Notopterygii 5-15 gram, Herba Cistanches 10-20 gram, Herba Artemisiae Anomalae 5-15 gram, Radix Angelicae Dahuricae 5-15 gram, Folium Camelliae sinensis 5-10 gram, Radix Paeoniae Rubra 5-15 gram, Fructus Cannabis 10-20 gram, Cortex Moutan 10-20 gram, Rhizoma Chuanxiong 10-15 gram, Massa Medicata Fermentata 5-15 gram, Cortex Phellodendri 10-15 gram, Rhizoma Paridis 5-15 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
10 grams, Flos Sophorae, Radix Angelicae Sinensis 20 grams, Flos Lonicerae 15 grams, Spina Gleditsiae 20 grams, Rhizoma Coptidis 15 grams, Herba Taraxaci 15 grams, the Radix Astragali 18 grams, Radix Sanguisorbae 12 grams, Rhizoma Alismatis 10 grams, 10 grams, Flos Carthami, 15 grams, Radix Glycyrrhizae, Medulla Junci 12 grams, Fructus Forsythiae 15 grams, Rhizoma Atractylodis 12 grams, Bulbus Fritillariae Thunbergii 10 grams, Fructus Aurantii 10 grams, Radix Rehmanniae 12 grams, Semen Arecae 12 grams, Rhizoma Et Radix Notopterygii 10 grams, Herba Cistanches 15 grams, Herba Artemisiae Anomalae 10 grams, the Radix Angelicae Dahuricae 10 grams, Folium Camelliae sinensis 8 grams, Radix Paeoniae Rubra 10 grams, Fructus Cannabis 15 grams, Cortex Moutan 15 grams, Rhizoma Chuanxiong 12 grams, Massa Medicata Fermentata 10 grams, Cortex Phellodendri 12 grams, Rhizoma Paridis 10 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Flos Sophorae: get crude drug, except destemming, leaf and impurity, sieve dedust bits;
(2) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(3) Flos Lonicerae: sieve removes silt, picks clean impurity;
(4) Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;
(5) Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
(6) Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
(7) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
(8) Radix Sanguisorbae: pick decontamination, washes, and slightly soaks, and runs through, and is cut into sheet, dries;
(9) Rhizoma Alismatis: pick decontamination, size stepping, be soaked in water to eighty per cant thoroughly, pull out, shine cool, moistening is even to inside and outside humidity, and section, dries;
(10) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(11) Radix Glycyrrhizae: extracting liquorice sheet, adds cooked Mel and boiled water is a little, mixes thoroughly, slightly vexed, and put in pot and fry to deepening yellow with slow fire, till tack-free, taking-up cools, 100 jin, every Radix Glycyrrhizae, with cooked Mel 25-30 jin;
(12) Medulla Junci: get Medulla Junci and put in pot, above cover the pot that a bore is smaller, paste with blank sheet of paper, two pots of junctions, use brine sludge sealing, do not make to lose heart, and being calcined to blank sheet of paper is that coke yellow is ceased fire, and takes out after cooling completely;
(13) Fructus Forsythiae: pick clean impurity, stranding is opened, except discarding stalk;
(14) Rhizoma Atractylodis: pick decontamination, with blister to seven, most probably thoroughly, pull out, run through rear section, dry;
(15) Bulbus Fritillariae Thunbergii: removing impurity, size stepping, cleans, runs through, cut sheet, dry, and sieve removes chip, or smashes;
(16) Fructus Aurantii: removing flesh, core, edulcoration, slightly soaks, and pulls out, softens, and till pinching doubling with hands, section, dries;
(17) Radix Rehmanniae: get crude drug, removing impurity, cleans, slightly moistens, cut sheet, dry, and sieve removes chip;
(18) Semen Arecae: pick decontamination, soaks with clear water, changes water, to soaking, pick up by temperature situation, and section, dries;
(19) Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
(20) Herba Cistanches: pick clean impurity, clear water soaks, and changes water every day 1-2 times, and as being salty Herba Cistanches, bubble is salinity to the greatest extent, runs through, longitudinal section, dries;
(21) Herba Artemisiae Anomalae: pick clean impurity, remove root, uses water edulcoration, slightly soaks, cutting, dry;
(22) Radix Angelicae Dahuricae: pick clean impurity, wash, soaks, pulls out and run through, slightly shine to crust without soapy feeling time, then after moistening, chip drying;
(23) Folium Camelliae sinensis: after fresh leaf gathers, through completing, knead, green tea is made in drying;
(24) Radix Paeoniae Rubra: get crude drug, removing impurity, size stepping, cleans, runs through, shave, dry, and sieve removes chip;
(25) Fructus Cannabis: pick decontamination and residual shell, get clean core;
(26) Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
(27) Rhizoma Chuanxiong: pick decontamination, separately large and small, be soaked in water, solarization is dried in the air, and cuts into slices after moistening, dry;
(28) Massa Medicata Fermentata: get wheat bran and sprinkle evenly in hot pot, cigarette of having waited, pours into Massa Medicata Fermentata, fry to yellow, take out, sieve removes wheat bran, cools;
(29) Cortex Phellodendri: pick decontamination, washes, and pulls out, runs through, and section or shredding, dry;
(30) Rhizoma Paridis: removing fibrous root, cleaning, drying;
(2) prepare
(1) Flos Sophorae cooked, Radix Angelicae Sinensis, Flos Lonicerae, Spina Gleditsiae, Rhizoma Coptidis, Herba Taraxaci, the Radix Astragali, Radix Sanguisorbae, Rhizoma Alismatis, Flos Carthami, Radix Glycyrrhizae, Medulla Junci, Fructus Forsythiae, Rhizoma Atractylodis, Bulbus Fritillariae Thunbergii, Fructus Aurantii, Radix Rehmanniae, Semen Arecae, Rhizoma Et Radix Notopterygii, Herba Cistanches, Herba Artemisiae Anomalae, the Radix Angelicae Dahuricae, Folium Camelliae sinensis, Radix Paeoniae Rubra, Fructus Cannabis, Cortex Moutan, Rhizoma Chuanxiong, Massa Medicata Fermentata, Cortex Phellodendri, Rhizoma Paridis are put into decocting container, add water 8 times amount, soak after 100 minutes, intense fire decocts boiling, use slow fire boiling again 20 minutes, filter first time decoction liquor, first time decoction liquor is poured in container;
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain second time decoction liquor;
(3) by twice decoction liquor mixing and stirring, 4 doses are divided into take.
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CN105902742A (en) * | 2016-05-20 | 2016-08-31 | 沈玲 | Dried alum and bile haemorrhoids powder for treating haemorrhoids and preparation method of dried alum and bile haemorrhoids powder |
CN107569625A (en) * | 2017-10-26 | 2018-01-12 | 杨莉 | A kind of medicine for treating discharging fresh blood stool and preparation method thereof |
ES2927996A1 (en) * | 2021-05-10 | 2022-11-14 | Beijing Marchheard Hightec Co | AN OINTMENT FOR HEMORRHOIDS AND THE METHOD OF PREPARING THE SAME (Machine-translation by Google Translate, not legally binding) |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105902742A (en) * | 2016-05-20 | 2016-08-31 | 沈玲 | Dried alum and bile haemorrhoids powder for treating haemorrhoids and preparation method of dried alum and bile haemorrhoids powder |
CN107569625A (en) * | 2017-10-26 | 2018-01-12 | 杨莉 | A kind of medicine for treating discharging fresh blood stool and preparation method thereof |
ES2927996A1 (en) * | 2021-05-10 | 2022-11-14 | Beijing Marchheard Hightec Co | AN OINTMENT FOR HEMORRHOIDS AND THE METHOD OF PREPARING THE SAME (Machine-translation by Google Translate, not legally binding) |
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