CN103768465B

CN103768465B - A kind of medicine for the treatment of hypochondriac pain and preparation method thereof

Info

Publication number: CN103768465B
Application number: CN201410038479.8A
Authority: CN
Inventors: 蒋玲
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-01-27
Filing date: 2014-01-27
Publication date: 2016-04-06
Anticipated expiration: 2034-01-27
Also published as: CN103768465A

Abstract

The invention discloses a kind of medicine for the treatment of hypochondriac pain and preparation method thereof, it is mainly prepared from according to a certain weight ratio by medicines such as Radix Gentianae, Gypsum Fibrosum, Herba Artemisiae Scopariae, Radix Bupleuri, Semen Trichosanthis, Flos Citri Sarcodactylis, Oletum Trogopteroris, medicine of the present invention has activating QI to eliminate phlegm, soothing the liver YANG invigorating, search the function that wind is drawn out pus by applying a plaster to the affected part, be used for the treatment of hypochondriac pain instant effect, good effect, have no side effect.

Description

A kind of medicine for the treatment of hypochondriac pain and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of hypochondriac pain and preparation method thereof, belong to the field of Chinese medicines.

Background technology

The disease that hypochondriac pain is is main manifestations with one or both sides side of body flank pain.Ancient also known as the side of body costalgia, hypochondriac pain or pain over the hypochondrium.The side of body refers to thoracotomy, for axil is with the general designation down to twelfth rib osseous part.Hypochondriac pain is symptom common in liver and gall diseases, and hypochondriac pain paathogenic factor has depression of liver-QI, blood stasis is at a stop, dampness-heat in the liver and gallbladder, deficiecny of liver-YIN etc., and its pathological changes is mainly in liver and gall.At present, western medicine hypochondriac pain poor effect, and long-term taking Western medicine has more side effect, therefore, there is very large demand to the Chinese medicine of rapid, effective treatment hypochondriac pain in people.

Summary of the invention

The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment hypochondriac pain, thus completes the present invention.

Object of the present invention is just to provide a kind of composition of medicine effectively can treating hypochondriac pain.

Another object of the present invention just there is provided the preparation method of this composition of medicine.

Medicine of the present invention selects Radix Gentianae, Gypsum Fibrosum, Herba Artemisiae Scopariae, Radix Bupleuri, Semen Trichosanthis, Flos Citri Sarcodactylis, Oletum Trogopterori, Caulis Perillae, Radix Glehniae, Herba Lysimachiae, Rhizoma Sparganii, Fructus Aurantii, Rhizoma Polygoni Cuspidati, the Radix Astragali, Myrrha, Polyporus, Rhizoma Paridis, Cortex Magnoliae Officinalis, Endothelium Corneum Gigeriae Galli, Thallus Laminariae (Thallus Eckloniae), Rhizoma Corydalis, Caulis Spatholobi, Pericarpium Citri Reticulatae Viride, Bungarus Parvus, Poria, the Radix Euphorbiae Pekinensis, Fructus Evodiae, Caulis Bambusae In Taenia, Radix Kansui, Spina Gleditsiae medicine to combine, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat the recurrence of hypochondriac pain.Wherein select Radix Gentianae to be that cold, enter liver, gallbladder meridian, have eliminating pathogen in the liver excess-fire, except the function of damp-heat in lower-JIAO, treating the liver is manic through intenseness of heat ， Jing Epilepsy, encephalitis B because its nature and flavor are bitter, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, carbuncle skin infection, scrotum swells and ache, pudendum pruritus due to damp pathogen.Gypsum Fibrosum is selected to be because its property acrid-sweet flavor, cold, enter lung, stomach warp, raw with there being expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst, controls calentura high fever and does not move back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, forges deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, bursts and does not regain, the burning hot wound of soup.Herba Artemisiae Scopariae is selected to be because its nature and flavor toil, cool, enter liver, spleen, urinary bladder channel, have the function of clearing away heat-damp and promoting diuresis, control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Select Radix Bupleuri to be that cool, enter liver, gallbladder meridian, have reconciling superficies and interior, soothing the liver, the function of yang invigorating, controls alternate attack of chill and fever, fullness in the chest and hypochondriac pain because its nature and flavor are bitter, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.Semen Trichosanthis is selected to be because its nature and flavor are sweet, cold, return lung, stomach, large intestine channel, have moistening the lung and resolving phlegm, the function of laxation relieving constipation, control cough caused by dryness expectorant and stick, dryness of the intestine constipation.Select Flos Citri Sarcodactylis to be because its nature and flavor are sad, temperature, has the function of activating QI to eliminate phlegm, treats for stomachache, coerce swollen, vomiting, dysphagic cough with asthma.Select Oletum Trogopterori to be because its property bitter but sweet flavor, temperature, enters liver, spleen channel, and raw by the function having promoting the circulation of blood pain relieving, control all pains of trusted subordinate's vim and vigour, women's amenorrhea, postnatal blood stasis is had a pain; External treatment Serpentis, scorpion, centipete bite, stir-fry is stopped blooding, and control metrorrhagia, menorrhagia, leucorrhea with bloody discharge is without cease.Select Caulis Perillae to be because its property acrid-sweet flavor, tepor, enter lung, stomach, lung three warp, regulate the flow of vital energy, Shu Yu, pain relieving, antiabortive function, controls the stagnation of QI, dyspepsia, and chest and diaphragm painful abdominal mass is vexed, epigastric pain, and nausea is got along well.Select Radix Glehniae to be that enter lung, spleen channel, have nourishing YIN and clearing away lung-heat, the function of expelling phlegm for arresting cough, controls lung-heat type cough, chronic consumptive disease chronic cough because its nature and flavor sweetness and bitterness is light, cool, the moon hinders dry pharynx, thirsty.Herba Lysimachiae is selected to be because its nature and flavor toil, cool, there is heat clearing away, diuresis, antitussive, detumescence, the function of removing toxic substances, subcutaneous ulcer of harnessing the Yellow River, edema, vesical calculus, malaria, lung abscess, cough, spit blood, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, infantile malnutrition ， Jing Epilepsy, carbuncle, skin ulcer tinea, eczema.Select Rhizoma Sparganii to be because its nature and flavor toil, flat, enter liver, spleen channel, have removing blood stasis, circulation of qi promoting, removing food stagnancy, the function ， Zhi lumps in the chest and abdomen of pain relieving, the solidifying band of QI and blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, and traumatic injury, skin ulcer swells hard.Fructus Aurantii is selected to be because its nature and flavor toil, cool, enter lung, spleen, large intestine channel, have dispelling the stagnated QI, row expectorant, the function of removing food stagnancy, control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.Select Rhizoma Polygoni Cuspidati to be because its nature and flavor are bitter, flat, dispel the wind, dampness removing, removing blood stasis with potent drugs, the function of stimulating the menstrual flow, dispelling the wind and dampness pathogens bones and muscles pain, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, women's amenorrhea, lochiostasis ， lumps in the chest and abdomen, anal fistula hematochezia, injury from falling down, scalds, malignant boil tinea disease.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Myrrha is selected to be that flat, enter Liver Channel, have loose blood blood stasis removing, the function of subduing swelling and relieving pain, controls and fall damage, incised wound, muscles and bones, trusted subordinate all Tong ， mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye because its nature and flavor are bitter.Select Polyporus to be because its property slightly sweet flavor, flat, enter spleen, kidney, urinary bladder channel, have the function of diuresis eliminating dampness by diuresis, control dysuria, edema distension, beriberi, has loose bowels, and drenches, turbid, leukorrhagia.Select Rhizoma Paridis to be because its nature and flavor are bitter, be slightly cold, slightly poisonous, return Liver Channel, have heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutter the pain of injury, convulsion with spasms.Select Cortex Magnoliae Officinalis to be because its nature and flavor toil, temperature, enter spleen, stomach, large intestine channel, have warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, dampness, the function of expectorant, control breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, cold-damp dysentery.Select Endothelium Corneum Gigeriae Galli to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, control stagnant, the function of strengthening the spleen and stomach, control food stagnation distension, vomiting regurgitation, dysentery, infantile malnutrition, quenches one's thirst, incontinence of urine, sore throat tonsillitis, ulcerative gingivitis aphtha.Select Thallus Laminariae (Thallus Eckloniae) to be because its nature and flavor are salty, cold, enter stomach warp, have softening the hard mass, the function of row water, controls scrofula, and goiter is dysphagic, edema, painful and swollen testis, leukorrhagia.Rhizoma Corydalis is selected to be that temperature, enter liver, stomach warp, invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, the function of pain relieving, controls all pains of trusted subordinate's waist knee joint, menoxenia ， mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury because its nature and flavor are worked hard.Select Caulis Spatholobi to be because its property bitter but sweet flavor, temperature, enters the heart, spleen two warp, have invigorate blood circulation, the function of relaxing muscles and tendons, control soreness of waist and knee joint, paralysis and numbness, menoxenia.Select Pericarpium Citri Reticulatae Viride to be that tepor, enters liver, gallbladder meridian, has soothing the liver dispelling the stagnated QI, the function of eliminating stagnation expectorant because its nature and flavor toil, control breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.Bungarus Parvus is selected to be that temperature, poisonous, return Liver Channel, dispel the wind, dredging collateral, relieving convulsion, the function of counteracting toxic substances, controls hemiplegia, numb limbs and tense tendons, tic spasm, tetanus, joint aches, rheumatoid arthritis stubborn, leprosy because its nature and flavor are sweet, salty.Select Poria to be because its property slightly sweet flavor, flat, enter the heart, spleen, lung meridian, have eliminating dampness and diuresis, strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming, control dysuria edema distending pain, phlegm retention cough with dyspnea, the sound of vomiting of vomitting, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.Select the Radix Euphorbiae Pekinensis to be because its nature and flavor toil, cold, poisonous, enter lung, spleen, kidney channel, have removing water retention by purgation to drink, profit two function just, harnesses the river swollen, dropsy, phlegm retention, scrofula, swollen ulcer drug.Select Fructus Evodiae to be because its nature and flavor are worked hard, temperature, poisonous, enter liver, stomach warp, have warming middle-JIAO, pain relieving, regulate the flow of vital energy, the function of dampness, stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.Select Caulis Bambusae In Taenia to be because its nature and flavor are sweet, cool, enter stomach, gallbladder meridian, have heat clearing away, removing heat from blood, reduce phlegm, the function of emesis, control dysphoria with smothery sensation vomiting, singultus, expectorant heat syndrome cough is breathed heavily, and spits blood, epistaxis, metrorrhagia, malignant histocytosis, fetal movement ， Jing Epilepsy.Select Radix Kansui to be because its property bitter but sweet flavor, cold, poisonous, enter spleen, lung, kidney channel, have removing water retention by purgation drink, removing mass gathers, and logical two functions just, swelling of harnessing the river is expired, prolonged fluid-retention, blocked-up chest, and epilepsy is dysphagic, lumps in the chest and abdomen, constipation and anuresis.Select Spina Gleditsiae to be that temperature, searches wind, draw out pus by applying a plaster to the affected part because its nature and flavor are pungent, detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.

Detailed description of the invention

The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight

Radix Gentianae 5-15 gram of Gypsum Fibrosum 10-20 gram of Herba Artemisiae Scopariae 15-25 gram

Radix Bupleuri 5-15 gram of Semen Trichosanthis 10-20 gram of Flos Citri Sarcodactylis 15-25 gram

Oletum Trogopterori 5-15 gram of Caulis Perillae 10-20 gram of Radix Glehniae 15-25 gram

Herba Lysimachiae 15-25 gram of Rhizoma Sparganii 10-20 gram of Fructus Aurantii 15-25 gram

Rhizoma Polygoni Cuspidati 15-25 gram of Radix Astragali 10-20 gram of Myrrha 15-25 gram

Polyporus 15-25 grammes per square metre building 10-20 gram Cortex Magnoliae Officinalis 15-25 gram

Endothelium Corneum Gigeriae Galli 5-15 gram of Thallus Laminariae (Thallus Eckloniae) 5-15 gram of Rhizoma Corydalis 10-20 gram

Caulis Spatholobi 5-15 gram of Pericarpium Citri Reticulatae Viride 5-15 gram of Bungarus Parvus 10-20 gram

Poria 5-15 gram of Radix Euphorbiae Pekinensis 5-15 gram of Fructus Evodiae 10-20 gram

Caulis Bambusae In Taenia 15-25 gram of Radix Kansui 10-20 gram of Spina Gleditsiae 15-25 gram

Preferable amount is

Radix Gentianae 10 grams of Gypsum Fibrosum 15 grams of Herba Artemisiae Scopariae 20 grams

Radix Bupleuri 10 grams of Semen Trichosanthis 15 grams of Flos Citri Sarcodactyliss 20 grams

Oletum Trogopterori 10 grams of Caulis Perillaes 15 grams of Radix Glehniaes 20 grams

Herba Lysimachiae 20 grams of Rhizoma Sparganii 15 grams of Fructus Aurantiis 20 grams

Rhizoma Polygoni Cuspidati 20 grams of Radixs Astragali 15 grams of Myrrhas 20 grams

15 grams, Polyporus 20 grammes per square metre building Cortex Magnoliae Officinalis 20 grams

Endothelium Corneum Gigeriae Galli 10 grams of Thallus Laminariae (Thallus Eckloniae)s 10 grams of Rhizoma Corydalis 15 grams

Caulis Spatholobi 10 grams of Pericarpium Citri Reticulatae Virides 10 grams of Bungarus Parvus 15 grams

Poria 10 grams, 10 grams of Radixs Euphorbiae Pekinensis Fructus Evodiae 15 grams

Caulis Bambusae In Taenia 20 grams of Radix Kansuis 15 grams of Spina Gleditsiaes 20 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Radix Gentianae: pick decontamination, removes residual stem, cleans, runs through rear cutting, dry;

2, Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter;

3, Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, after the clean spare of basket sieve;

4, Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear section, dry;

5, Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;

6, Flos Citri Sarcodactylis: gather during flower thinning before sunrise in morning, or pickup fallen flowers, dry or dry;

7, Oletum Trogopterori: pick clean impurity, smashes or sieves dedust bits;

8, Caulis Perillae: removing impurity, after being soaked in water, runs through, and section, dries;

9, Radix Glehniae: pick decontamination, removing stem foot, slightly washes with water, pulls out, slightly moisten, cutting, dry;

10, Herba Lysimachiae: pick clean impurity, sieve dedust bits, dry;

11, Rhizoma Sparganii: pick clean impurity, be soaked in water, pull out and run through, section, dries;

12, Fructus Aurantii: removing flesh, core, edulcoration, slightly soaks, and pulls out, softens, and section, dries;

13, Rhizoma Polygoni Cuspidati: get crude drug, removing impurity, cleaning, drying, split broken;

14, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;

15, Myrrha: pick decontamination, breaks into fragment;

16, Polyporus: clean silt particle, soften section, dry;

17, Rhizoma Paridis: removing fibrous root, cleaning, drying;

18, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;

19, Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;

20, Thallus Laminariae (Thallus Eckloniae): pick decontamination, rinses with water, is cut into wide silk, dries;

21, Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;

22, Caulis Spatholobi: run through with water, section, or steam soft rear section, dry;

23, Pericarpium Citri Reticulatae Viride: pick clean impurity, be soaked in water, pull out, run through, section, dries;

24, Bungarus Parvus: get crude drug, removing bamboo let and head, used time cutting;

25, Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;

26, the Radix Euphorbiae Pekinensis: pick decontamination, washes, and runs through, and cutting or section, dry;

27, Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;

28, Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;

29, Radix Kansui: pick decontamination, rinses with water, pulls out, dries;

30, Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries.

Two, prepare

1, the Radix Gentianae of described weight, Gypsum Fibrosum, Herba Artemisiae Scopariae, Radix Bupleuri, Semen Trichosanthis, Flos Citri Sarcodactylis, Oletum Trogopterori, Caulis Perillae, Radix Glehniae, Herba Lysimachiae, Rhizoma Sparganii, Fructus Aurantii, Rhizoma Polygoni Cuspidati, the Radix Astragali, Myrrha, Polyporus, Rhizoma Paridis, Cortex Magnoliae Officinalis, Endothelium Corneum Gigeriae Galli, Thallus Laminariae (Thallus Eckloniae), Rhizoma Corydalis, Caulis Spatholobi, Pericarpium Citri Reticulatae Viride, Bungarus Parvus, Poria, the Radix Euphorbiae Pekinensis, Fructus Evodiae, Caulis Bambusae In Taenia, Radix Kansui, Spina Gleditsiae medicine are decocted with water secondary, first time adds 6 times of water gagings and soaks, soak after 90 minutes, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor.

2, add water the medicinal residues of filtration 5 times amount, and intense fire decocts boiling, then uses slow fire boiling 40 minutes, filters to obtain second time decoction liquor.

3, by twice decoction liquor mixing, then simmer in water 10 minutes, decoction liquor be divided into 6 doses to take.

Medicine of the present invention has reconciling superficies and interior, and activating QI to eliminate phlegm is soothing the liver, effect of yang invigorating, is used for the treatment of hypochondriac pain short treating period, instant effect, non-relapse after healing, has no side effect.

Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples include animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] Drug therapy hypochondriac pain of the present invention

1, physical data

Accept out-patient's totally 173 examples for medical treatment.

2, diagnostic criteria

To coerce the disease that flank one or both sides pain is main manifestations.Under liver occupies the side of body, its passages through which vital energy circulates is distributed in two sides of body, the gallbladder being attached to the liver, and its arteries and veins also follows in the side of body, so hypochondriac pain is how relevant with liver and gall diseases.All depressed emotions, depression of liver-QI, or surfeit delicious food, be addicted to drink immoderate, or weakness due to chronic disease, melancholy,anxiety and overstrain, or tumbling down wound etc. all can cause hypochondriac pain.Time dialectical, should first divide QI and blood deficiency and excess, general stagnation of QI person mostly is distending pain, and sore spot migration is indefinite.Blood stasis person mostly is twinge, localized pain.Deficiency syndrome hypochondriac pain has a dull ache more, and the many pain bursts of excess syndrome hypochondriac pain, pain gesture is more acute.

3, Therapeutic Method

Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 10 days, is a course for the treatment of, takes 4 courses for the treatment of continuously.

4, efficacy assessment standard

Effective: hypochondriac pain transference cure, body constitution recovers normal;

Take a turn for the better: hypochondriac pain symptom is clearly better, and body constitution is progressively recovered;

Invalid: not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, by Drug therapy hypochondriac pain patient 173 example of the present invention, effective 164 examples of result, obvious effective rate is 94.8%, and take a turn for the better 6 examples, and improvement rate is 3.47%, and invalid 3 examples, total effective rate is 98.27%.

Claims

1. treat a medicine for hypochondriac pain, it is characterized in that: it is made up of the crude drug in following weight range:

Caulis Bambusae In Taenia 15-25 gram of Radix Kansui 10-20 gram of Spina Gleditsiae 15-25 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Caulis Bambusae In Taenia 20 grams of Radix Kansuis 15 grams of Spina Gleditsiaes 20 grams.

3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:

(1) get the raw materials ready

(1) Radix Gentianae: pick decontamination, removes residual stem, cleans, runs through rear cutting, dry;

(2) Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter;

(3) Herba Artemisiae Scopariae: sieve, picks decontamination, and removing undesirable root, pulverizes, after the clean spare of basket sieve;

(4) Radix Bupleuri: pick decontamination, removes residual stem, cleans silt, pulls out, run through rear section, dry;

(5) Semen Trichosanthis: get crude drug, remove shrivelled seed, impurity, the used time smashs to pieces;

(6) Flos Citri Sarcodactylis: gather during flower thinning before sunrise in morning, or pickup fallen flowers, dry or dry;

(7) Oletum Trogopterori: pick clean impurity, smashes or sieves dedust bits;

(8) Caulis Perillae: removing impurity, after being soaked in water, runs through, and section, dries;

(9) Radix Glehniae: pick decontamination, removing stem foot, slightly washes with water, pulls out, slightly moisten, cutting, dry;

(10) Herba Lysimachiae: pick clean impurity, sieve dedust bits, dry;

(11) Rhizoma Sparganii: pick clean impurity, be soaked in water, pull out and run through, section, dries;

(12) Fructus Aurantii: removing flesh, core, clean, slightly soak, pull out, soften, section, dries;

(13) Rhizoma Polygoni Cuspidati: get crude drug, removing impurity, cleaning, drying, split broken;

(14) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;

(15) Myrrha: pick decontamination, breaks into fragment;

(16) Polyporus: clean silt particle, soften section, dry;

(17) Rhizoma Paridis: removing fibrous root, cleaning, drying;

(18) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrapes off rough bark after running through, and clean, shredding, dries;

(19) Endothelium Corneum Gigeriae Galli: pick decontamination, rinses and dries;

(20) Thallus Laminariae (Thallus Eckloniae): pick decontamination, rinses with water, is cut into wide silk, dries;

(21) Rhizoma Corydalis: pick decontamination, is soaked in water, and clean, solarization is dried in the air, and profit is even to inside and outside humidity, cuts into slices or smashes;

(22) Caulis Spatholobi: run through with water, section, or steam soft rear section, dry;

(23) Pericarpium Citri Reticulatae Viride: pick clean impurity, be soaked in water, pull out, run through, section, dries;

(24) Bungarus Parvus: get crude drug, removing bamboo let and head, used time cutting;

(25) Poria: be soaked in water, cleans and pulls out, and after vexed, section, dries;

(26) Radix Euphorbiae Pekinensis: pick decontamination, washes, and runs through, and cutting or section, dry;

(27) Fructus Evodiae: get crude drug, removing fruit stem, branch and impurity, sieve removes chip;

(28) Caulis Bambusae In Taenia: remove hard bamboo let, impurity, shakes off ash bits, is kneaded into little group or cutting;

(29) Radix Kansui: pick decontamination, rinses with water, pulls out, dries;

(30) Spina Gleditsiae: pick decontamination, is soaked in water, and runs through rear section, dries;

(2) prepare

(1) Radix Gentianae of described weight, Gypsum Fibrosum, Herba Artemisiae Scopariae, Radix Bupleuri, Semen Trichosanthis, Flos Citri Sarcodactylis, Oletum Trogopterori, Caulis Perillae, Radix Glehniae, Herba Lysimachiae, Rhizoma Sparganii, Fructus Aurantii, Rhizoma Polygoni Cuspidati, the Radix Astragali, Myrrha, Polyporus, Rhizoma Paridis, Cortex Magnoliae Officinalis, Endothelium Corneum Gigeriae Galli, Thallus Laminariae (Thallus Eckloniae), Rhizoma Corydalis, Caulis Spatholobi, Pericarpium Citri Reticulatae Viride, Bungarus Parvus, Poria, the Radix Euphorbiae Pekinensis, Fructus Evodiae, Caulis Bambusae In Taenia, Radix Kansui, Spina Gleditsiae medicine are decocted with water secondary, first time adds 6 times of water gagings and soaks, soak after 90 minutes, intense fire decocts boiling 10 minutes, use slow fire boiling again 25 minutes, filter first time decoction liquor;

(2) add water the medicinal residues of filtration 5 times amount, and intense fire decocts boiling, then uses slow fire boiling 40 minutes, filters to obtain second time decoction liquor;

(3) by twice decoction liquor mixing, then simmer in water 10 minutes, decoction liquor be divided into 6 doses to take.