Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and clinical test repeatedly and checking, finally have found the medicine of effectively treatment catarrhal conjunctivitis, thus completes the present invention.
Object of the present invention is just to provide a kind of composition of medicine effectively can treating catarrhal conjunctivitis.
Another object of the present invention just there is provided the preparation method of this composition of medicine.
Herba Asari selected by medicine of the present invention, Flos Chrysanthemi, Periostracum Cicadae, Fructus Arctii, the Fructus Kochiae, Flos Eriocauli, Spora Lygodii, Herba Schizonepetae, Zaocys, Herba Centipedae, Semen Cassiae, Cortex Fraxini, Rhizoma Paridis, Cortex Dictamni, Indigo Naturalis, Mirabilitum crystallina, Herba Taraxaci, Radix Cynanchi Atrati, Herba Violae, Rhizoma Et Radix Notopterygii, Radix Isatidis, Pericarpium Zanthoxyli, Herba Equiseti Hiemalis, Semen Armeniacae Amarum, Radix Curcumae, Fructus Gardeniae, Fructus Leonuri, Gypsum Fibrosum, Flos Lonicerae, Rhizoma Coptidis, Fructus Tribuli, Herba Setariae Viridis, Rhizoma Phragmitis, Pseudobulbus Bletillae (Rhizoma Bletillae), Cortex Moutan, Spica Prunellae, Herba Erodii, Mel medicine carries out combining, each efficacy of drugs is made by these drug regimens to produce synergism, thus effectively can treat the recurrence of catarrhal conjunctivitis.Wherein select Herba Asari to be that temperature, enters lung, kidney channel, dispel the wind, cold expelling, row water because its nature and flavor are pungent, open the function of stealing, control air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Flos Chrysanthemi is selected to be that cool, enter lung, Liver Channel, have dispelling wind, disappear heat, improving eyesight, and the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling because its nature and flavor sweetness and bitterness.Select Periostracum Cicadae to be because its property sweet-salty, cool, enter lung, Liver Channel, have loose wind heat, lung qi dispersing, determine the function of convulsion, control affection due to external wind and heat, cough hoarseness, measles is sent out not smooth thoroughly, and rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Select Fructus Arctii to be that cool, enter lung, stomach warp, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating, controls cough due to pathogenic wind-heat, laryngopharynx swelling and pain because its nature and flavor are worked hard, macule is not saturating, and rubella is had an itch, carbuncle sore tumefacting virus.Select the Fructus Kochiae to be because its nature and flavor sweetness and bitterness, cold, enter kidney, urinary bladder channel, have diuresis, the function of clearing away damp-heat, controls dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.Flos Eriocauli is selected to be that flat, return liver, lung meridian, have dispelling wind and heat pathogens, improving eyesight, nebula removing, control wind heat conjunctival congestion, swell and ache photophobia, nebula of looking unfamiliar film, headache due to pathogenic wind-heat because its nature and flavor are pungent, sweet.Select Spora Lygodii to be because its property slightly sweet flavor, cold, enter small intestinal, urinary bladder channel, have heat-clearing and toxic substances removing, the function of relieving stranguria by diuresis, controls urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster.Select Herba Schizonepetae to be that temperature, enters lung, Liver Channel, deliver, dispel the wind, the function for the treatment of blood disorders because its nature and flavor are pungent, parch to black stops blooding, and cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, and spit blood, epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Zaocys is selected to be because its nature and flavor are sweet, flat, return Liver Channel, have dispelling, collateral-activating, spasmolytic, dispelling the wind and dampness pathogens arthralgia pain, numb limbs and tense tendons, tic spasm, skin pruritus, leprosy.Select Herba Centipedae to be that temperature, enters meridian of Hand-TAI YIN edema caused by disorder of QI, dispel the wind, cold expelling because its nature and flavor are pungent, victory is wet, removing nebula, the function of stuffy nose relieving plug, cure cold, asthma of cold-type, sore throat, pertussis, eruptive disease is suffered from abdominal pain, amebic dysentery, malaria, infantile malnutrition with diarrhea, nasal sinusitis, polyp, corneal nebula is puckery itches, ecthyma, scabies, traumatic injury.Semen Cassiae is selected to be because its property bitter but sweet flavor, cool, enter liver, kidney channel, have liver heat removing, improving eyesight, diuretic, the function of relieving constipation, control wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, liver cirrhosis abdomen, habitual constipation.Cortex Fraxini is selected to be that cold, enter liver, gallbladder meridian, have the hot dampness that disappears, antiasthmatic-antitussive, the function of improving eyesight, controls bacillary dysentery, enteritis, leucorrhea, chronic tracheitis, conjunctival congestion and swelling pain, epiphora induced by wind, psoriasis because its nature and flavor are bitter.Select Rhizoma Paridis to be because its nature and flavor are bitter, be slightly cold, slightly poisonous, return Liver Channel, have heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutter the pain of injury, convulsion with spasms.Cortex Dictamni is selected to be because its nature and flavor are bitter, salty, cold, enter spleen, stomach warp, dispel the wind, dampness, heat clearing away, the function of removing toxic substances, control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.Select Indigo Naturalis to be because its nature and flavor are salty, cold, enter liver, lung, stomach warp, have heat clearing away, removing heat from blood, the function of removing toxic substances, control epidemic febrile disease intenseness of heat, macule, spit blood, spit blood, little Jing Epilepsy, skin ulcer swells, erysipelas, snake bite and insect sting.Mirabilitum crystallina is selected to be because its nature and flavor are pungent salty, cold, enter the heart, stomach, kidney channel, have resolving heat and reducing pathogenic fire, sharp key, the function of detumescence, row calentura when controlling, accumulated heat excessive thirst, vomit and diarrhoea, edema, urine retention, bleeding from the gum, erysipelas, scald.Select Herba Taraxaci to be because its property bitter but sweet flavor, cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Radix Cynanchi Atrati to be that cold, enter lung, stomach, kidney channel, have heat clearing away, the function of removing heat from blood, controls yin asthenia generating intrinsic heat, the scorching hot hypersomnia of rheumatism, lung-heat hemoptysis, pyrexial malaria, intermittent high fever because its nature and flavor hardship is salty, puerperal fidgets due to deficiency syncope due to excessive bleeding, pyretic stranguria, stranguria with blood, rheumatalgia, scrofula.Select Herba Violae to be that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because its nature and flavor bitter, acrid, cold, the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Rhizoma Et Radix Notopterygii is selected to be that temperature, enter bladder, kidney channel, have loose exterior cold, wind-damp dispelling, the function in sharp joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore because its nature and flavor are worked hard.Select Radix Isatidis to be because its nature and flavor are bitter, cold, enter liver, stomach blood system, have heat clearing away, removing toxic substances, the function of removing heat from blood, controls influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, and pyretic toxicity sends out speckle, and coma tells nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash.Pericarpium Zanthoxyli is selected to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, lung, kidney channel, have warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separate fish raw meat poison, control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.Herba Equiseti Hiemalis is selected to be because its nature and flavor sweetness and bitterness, flat, enter lung, liver, gallbladder meridian, have wind-dispelling heat-dissipating, expelling pathogenic factors from muscles, the function of nebula removing, control the raw nebula of order, epiphora induced by wind, discharging fresh blood stool, dysentery, proctoptosis, malaria, laryngalgia, carbuncle.Semen Armeniacae Amarum is selected to be that temperature, poisonous, enter lung, large intestine channel, have expelling phlegm for arresting cough, relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation because its nature and flavor are bitter.Radix Curcumae is selected to be because its nature and flavor are worked hard, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, control all pains of breast abdomen side of body rib, lose the heart demented, calentura coma, spit blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, have heat clearing away, pathogenic fire purging, the function of removing heat from blood, control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Fructus Leonuri to be that enter heart born of the same parents, Liver Channel, have promoting blood flow to regulate menstruation, the function of wind and heat dispersing, controls menoxenia, metrorrhagia leukorrhagia, and postnatal blood stasis is had a pain because its nature and flavor are sweet pungent, cool, liver-heat is had a headache, conjunctival congestion and swelling pain, or raw nebula film.Gypsum Fibrosum is selected to be because its property acrid-sweet flavor, cold, enter lung, stomach warp, raw with there being expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst, controls calentura high fever and does not move back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, forges deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, bursts and does not regain, the burning hot wound of soup.Flos Lonicerae is selected to be because its nature and flavor are sweet, cold, enter lung, stomach warp, have heat clearing away, the function of removing toxic substances, control epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Rhizoma Coptidis is selected to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, have pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, and diarrhea of heat type is suffered from abdominal pain, pulmonary tuberculosis, tells, is defeated in battle, hematochezia, quenches one's thirst, infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Fructus Tribuli to be because its nature and flavor toil, temperature, enter liver, lung meridian, have loose wind, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, the function of promoting the circulation of blood, controls headache, itching over the body, and conjunctival congestion swells nebula, and fullness in the chest, cough with dyspnea , mass in the abdomen, breast is difficult, carbuncle, scrofula.Herba Setariae Viridis is selected to be that have heat extraction, dry, the function of detumescence, controls carbuncle, skin ulcer tinea, acute conjunctivitis because its nature and flavor are cool, light.Rhizoma Phragmitis is selected to be that cold, enter lung, stomach warp, has heat clearing away, promotes the production of body fluid, relieving restlessness, and the function of preventing or arresting vomiting controls calentura excessive thirst, gastropyretic vomiting, dysphagic, regurgitation, consumptive lung disease, lung abscess, and separates Fugu ocellatus ichthyotoxin because its nature and flavor are sweet.Select Pseudobulbus Bletillae (Rhizoma Bletillae) to be because its property bitter but sweet flavor, cool, enter lung meridian, have tonifying the lung, hemostasis, detumescence, raw sight, the function of sore, control lung and hinder hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, canker sores, and soup fire is burnt, rhagadia manus et pedis.Cortex Moutan is selected to be because its nature and flavor are worked hard, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, and send out speckle , Jing Epilepsy, tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Spica Prunellae to be because its nature and flavor toil, cold, enter liver, gallbladder meridian, have liver heat removing, the function of eliminating stagnation, controls scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Select Herba Erodii to be because its nature and flavor toil, dispel the wind, invigorate blood circulation, the function of heat-clearing and toxic substances removing, dispelling the wind and dampness pathogens pain, contracture is numb, carbuncle, traumatic injury, enteritis, dysentery.Select Mel to be that flat, enter lung, spleen, large intestine channel, have invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup because its nature and flavor are sweet, separate Aconitum Carmichaeli.
Detailed description of the invention
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Herba Asari 8-15 gram of Flos Chrysanthemi 8-15 gram of Periostracum Cicadae 8-15 gram
Fructus Arctii 8-15 gram of Fructus Kochiae 8-15 gram of Flos Eriocauli 8-15 gram
Spora Lygodii 10-20 gram of Herba Schizonepetae 8-15 gram of Zaocys 6-10 gram
Herba Centipedae 8-15 gram of Semen Cassiae 6-10 gram of Cortex Fraxini 8-15 gram
Rhizoma Paridis 8-15 gram of Cortex Dictamni 8-15 gram Indigo Naturalis 8-15 gram
Mirabilitum crystallina 6-10 gram of Herba Taraxaci 8-15 gram of Radix Cynanchi Atrati 8-15 gram
Herba Violae 8-15 gram of Rhizoma Et Radix Notopterygii 6-10 gram of Radix Isatidis 15-20 gram
Pericarpium Zanthoxyli 6-10 gram of Herba Equiseti Hiemalis 8-15 gram of Semen Armeniacae Amarum 8-15 gram
Radix Curcumae 8-15 gram of Fructus Gardeniae 8-15 gram of Fructus Leonuri 8-15 gram
Gypsum Fibrosum 3-6 gram of Flos Lonicerae 8-15 gram of Rhizoma Coptidis 6-10 gram
Fructus Tribuli 8-15 gram of Herba Setariae Viridis 8-15 gram of Rhizoma Phragmitis 8-15 gram
Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15 gram of Cortex Moutan 8-15 gram of Spica Prunellae 8-15 gram
Herba Erodii 10-20 gram of Mel 6-15 gram
Preferable amount is
Herba Asari 10 grams of Flos Chrysanthemis 10 grams of Periostracum Cicadaes 10 grams
Fructus Arctii 10 grams of Fructus Kochiae 10 grams of Flos Eriocaulis 10 grams
Spora Lygodii 15 grams of Herba Schizonepetae 10 grams of Zaocyss 8 grams
Herba Centipedae 10 grams of Semen Cassiaes 8 grams of Cortex Fraxinis 10 grams
Rhizoma Paridis 10 grams of Cortex Dictamni 10 grams of Indigo Naturaliss 10 grams
Mirabilitum crystallina 8 grams of Herba Taraxacis 10 grams of Radix Cynanchi Atratis 10 grams
Herba Violae 10 grams of Rhizoma Et Radix Notopterygiis 8 grams of Radix Isatidis 18 grams
10 grams, Pericarpium Zanthoxyli 8 grams of Herba Equiseties Hiemalis 10 grams of Semen Armeniacae Amarums
Radix Curcumae 10 grams of Fructus Gardeniaes 10 grams of Fructus Leonuris 12 grams
Gypsum Fibrosum 5 grams of Flos Loniceraes 10 grams of Rhizoma Coptidis 6 grams
Fructus Tribuli 10 grams of Herba Setariae Viridis 10 grams of Rhizoma Phragmitiss 10 grams
Pseudobulbus Bletillae (Rhizoma Bletillae) 10 grams of Cortex Moutans 10 grams of Spica Prunellaes 10 grams
Herba Erodii 15 grams of Mel 10 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Herba Asari: Ex-all impurity, by water spray profit, timely cutting, dries;
2, Flos Chrysanthemi: pick clean leaf stalk, anthocaulus and spare impurity;
3, Periostracum Cicadae: pick decontamination, cleans and dries;
4, Fructus Arctii: pick decontamination, sieve removes spare;
5, the Fructus Kochiae: get crude drug, removing impurity, sieve removes chip;
6, Flos Eriocauli: removing sheath, impurity, cutting;
7, Spora Lygodii: get crude drug, crosses dusting cover, and sieve gets spore, removing impurity;
8, Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;
9, Zaocys: get crude drug, brush away ash bits, the used time decaptitates, squama, cutting;
10, Herba Centipedae: pick clean impurity, cutting, dry;
11, Semen Cassiae: get clean Semen Cassiae, putting in pot to fry has fragrance to micro-, takes out, cools;
12, Cortex Fraxini: pick decontamination, cleans, runs through rear stripping and slicing or cutting, dry;
13, Rhizoma Paridis: removing fibrous root, cleaning, drying;
14, Cortex Dictamni: pick clean impurity, removing rough bark, cleans, slightly moistens, and section, dries;
15, Indigo Naturalis: pick decontamination, sieves;
16, Mirabilitum crystallina: get crude drug, removing impurity, cleaning, drying, break into fragment;
17, Herba Taraxaci: pick decontamination, clean earth, cutting, dries;
18, Radix Cynanchi Atrati: pick clean impurity, removing stem Seedling, cleans, slightly soaks, run through, cutting, dry;
19, Herba Violae: get crude drug, removing impurity, cleans, slightly dries in the air, cutting, dry;
20, Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
21, Radix Isatidis: pick clean impurity, cleans, runs through, and section, dries;
22, Pericarpium Zanthoxyli: removing fruit stem and seed, Semen zanthoxyli, puts stir-fry in pot and, to making sound, takes out, cool;
23, Herba Equiseti Hiemalis: clean, slightly moisten, cut off root, cutting, dry;
24, Semen Armeniacae Amarum: pick clean impurity, put in boiling water and slightly boil, pulls out when crust micro-wrinkle, in leaching cold water, sloughs seed coat, dries, and winnows with a dustpan clean;
25, Radix Curcumae: be soaked in water, cleans, pulls solarization out and dry in the air, run through, and section, dries;
26, Fructus Gardeniae: sieve dedust bits, pick decontamination, pulverize and sieve or cut off two ends;
27, Fructus Leonuri: extract Herb during fruit maturation, dries, and lays fruit, picks debranching leaf, well sifted impurity;
28, Gypsum Fibrosum: remove assorted stone, cleans earth, is broken into fritter;
29, Flos Lonicerae: sieve removes silt, picks clean impurity;
30, Rhizoma Coptidis: pick decontamination, cleans silt particle, runs through, and section, dries in the shade;
31, Fructus Tribuli: silt is removed in drift, the hard thorn that Ex-all is residual;
32, Herba Setariae Viridis: summer, autumn gather, and dry;
33, Rhizoma Phragmitis: pick decontamination and root, cutting, dry;
34, Pseudobulbus Bletillae (Rhizoma Bletillae): pick decontamination, is soaked in water, and pulls out, dries in the air even to inside and outside humidity, and section is dry;
35, Cortex Moutan: pick decontamination, removing core, cleans, runs through, and section, dries;
36, Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
37, Herba Erodii: pick decontamination, removing undesirable root, washes, pulls out, cutting, dry;
38, Mel: get pure Mel, temper with slow fire, filters skimming.
Two, prepare
1, by the Herba Asari of described weight, Flos Chrysanthemi, Periostracum Cicadae, Fructus Arctii, the Fructus Kochiae, Flos Eriocauli, Spora Lygodii, Herba Schizonepetae, Zaocys, Herba Centipedae, Semen Cassiae, Cortex Fraxini, Rhizoma Paridis, Cortex Dictamni, Indigo Naturalis, Mirabilitum crystallina, Herba Taraxaci, Radix Cynanchi Atrati, Herba Violae, Rhizoma Et Radix Notopterygii, Radix Isatidis, Pericarpium Zanthoxyli, Herba Equiseti Hiemalis, Semen Armeniacae Amarum, Radix Curcumae, Fructus Gardeniae, Fructus Leonuri, Gypsum Fibrosum, Flos Lonicerae, Rhizoma Coptidis, Fructus Tribuli, Herba Setariae Viridis, Rhizoma Phragmitis, Pseudobulbus Bletillae (Rhizoma Bletillae), Cortex Moutan, Spica Prunellae, Herba Erodii, Mel decocts with water twice, add water 6 times amount for the first time, intense fire decocts boiling 10 minutes, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, add water medicinal residues after first time filtration 4 times amount, decocts boiling, then within 20 minutes, namely obtain second time decoction liquor with slow fire boiling.
3, by the mixing of twice decoction liquor, intense fire decocts, then with slow fire boiling 10 minutes and get final product, decoction liquor is divided into 6 doses to take.
Medicine of the present invention has heat clearing away, removing toxic substances, liver heat removing, improving eyesight, effect of diuretic, and treatment catarrhal conjunctivitis instant effect, short treating period, do not recur.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.4kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient 235 example for medical treatment.
2, diagnostic criteria
1. wind overweights pattern of fever
Patient's blepharoedema, hyperemia of the bulbar conjunctiva, sufferings double as, the many tear of photophobia, headache nasal obstruction, fever with aversion to wind.
2. wind type is hankered after
Show as white of the eye edema, more very, born of the same parents' eyelid is red and swollen for swelling pain, hot tears as soup, adversion to heat and photophobia, thirsty yellowish urine.
3. wind heat is also heavy
Disease sees that white of the eye is red heavy, and sufferings have concurrently, aversion to cold photophobia, headache nasal obstruction, heating, thirst with desire to drink, constipation dark coloured urine.With the passing of time lose the person of controlling, can change into chronic.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, each serving with 1 dose, every day is early, middle and late respectively takes 1 time, within 5 days, is a course for the treatment of, takes 4 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: catarrhal conjunctivitis is eliminated, without recurring after observing half a year;
Take a turn for the better: catarrhal conjunctivitis symptom is clearly better;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy catarrhal conjunctivitis patient 235 example of the present invention, effective 223 examples of result, obvious effective rate is 94.9%, and take a turn for the better 8 examples, and improvement rate is 3.4%, and invalid 4 examples, total effective rate is 98.3%.