Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment catarrhal conjunctivitis, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat catarrhal conjunctivitis.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention is to select Herba Asari, Flos Chrysanthemi, Periostracum Cicadae, Fructus Arctii, the Fructus Kochiae, Flos Eriocauli, Spora Lygodii, Herba Schizonepetae, Zaocys, Herba Centipedae, Semen Cassiae, Cortex Fraxini, Rhizoma Paridis, Cortex Dictamni, Indigo Naturalis, Mirabilitum crystallina, Herba Taraxaci, Radix Cynanchi Atrati, Herba Violae, Rhizoma Et Radix Notopterygii, Radix Isatidis, Pericarpium Zanthoxyli, Herba Equiseti Hiemalis, Semen Armeniacae Amarum, Radix Curcumae, Fructus Gardeniae, Fructus Leonuri, Gypsum Fibrosum, Flos Lonicerae, Rhizoma Coptidis, Fructus Tribuli, Herba Setariae Viridis, Rhizoma Phragmitis, Pseudobulbus Bletillae (Rhizoma Bletillae), Cortex Moutan, Spica Prunellae, Herba Erodii, Mel medicine combines, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the recurrence of catarrhal conjunctivitis.Wherein select Herba Asari to be because its nature and flavor are pungent, temperature, enters lung, kidney channel, dispel the wind, and cold expelling, row water, opens the function of stealing, and controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Flos Chrysanthemi to be because its nature and flavor sweetness and bitterness is cool, enter lung, Liver Channel, has dispelling wind, the heat that disappears, and improving eyesight, the function of removing toxic substances, controls headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.Selecting Periostracum Cicadae is because its property sweet-salty, cool, enters lung, Liver Channel, has loose wind heat, and lung qi dispersing determine the function of convulsion, controls affection due to external wind and heat, cough hoarseness, and measles is thoroughly not smooth, rubella pruritus, little youngster shies Epilepsy, conjunctival congestion, cataracta, furuncle swelling toxin, tetanus.Select Fructus Arctii to be because its nature and flavor are arduous, cool, enter lung, stomach warp, have dispelling wind and heat pathogens, lung qi dispersing rash, the function of subduing swelling and detoxicating, controls cough due to pathogenic wind-heat, laryngopharynx swelling and pain, macule is not saturating, and rubella is had an itch, carbuncle sore tumefacting virus.Select the Fructus Kochiae to be because its nature and flavor sweetness and bitterness is cold, enter kidney, urinary bladder channel, have diuresis, the function of clearing away damp-heat, controls dysuria, gonorrhea, leukorrhagia, hernia, rubella, sore, scabies, pudendum pruritus due to damp pathogen.Select Flos Eriocauli to be because its nature and flavor are pungent, sweet, flat, return liver, lung meridian, there is dispelling wind and heat pathogens, improving eyesight, nebula removing, controls wind heat conjunctival congestion, the photophobia that swells and ache, the nebula of looking unfamiliar film, headache due to pathogenic wind-heat.Select Spora Lygodii to be because its property slightly sweet flavor is cold, enter small intestinal, urinary bladder channel, have heat-clearing and toxic substances removing, the function of relieving stranguria by diuresis, controls urinary tract infection, lithangiuria, nebulousurine, leucorrhea, hepatitis, oedema due to nephritis, laryngopharynx swelling and pain, mumps, enteritis, dysentery, skin eczema, herpes zoster.Select Herba Schizonepetae to be because its nature and flavor are pungent, temperature, enters lung, Liver Channel, delivers, dispel the wind, and the function for the treatment of blood disorders, parch to black hemostasis, the heating that cures cold, headache, laryngopharynx swelling and pain, apoplexy locked mouth, spits blood, and epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Select Zaocys to be because its nature and flavor are sweet, flat, return Liver Channel, there is dispelling, collateral-activating, spasmolytic, dispelling the wind and dampness pathogens arthralgia pain, numb limbs and tense tendons, tic spasm, skin pruritus, leprosy.Select Herba Centipedae to be because its nature and flavor are pungent, temperature, enters meridian of Hand-TAI YIN edema caused by disorder of QI, dispel the wind, and cold expelling, victory is wet, removing nebula, the function of stuffy nose relieving plug, cure cold, asthma of cold-type, sore throat, pertussis, eruptive disease stomachache, amebic dysentery, malaria, infantile malnutrition with diarrhea, nasal sinusitis, polyp, corneal nebula is puckery itches, ecthyma, scabies, traumatic injury.Select Semen Cassiae to be because its property bitter but sweet flavor is cool, enter liver, kidney channel, have liver heat removing, improving eyesight, diuretic, the function of relieving constipation, controls wind heat acute conjunctivitis, optic atrohic blindness, nyctalopia, hypertension, hepatitis, liver cirrhosis abdomen, habitual constipation.Select Cortex Fraxini to be because its nature and flavor are bitter, cold, enter liver, gallbladder meridian, there is the hot dampness that disappears, antiasthmatic-antitussive, the function of improving eyesight, controls bacillary dysentery, enteritis, leucorrhea, chronic tracheitis, conjunctival congestion and swelling pain, epiphora induced by wind, psoriasis.Select Rhizoma Paridis to be because its nature and flavor are bitter, be slightly cold, slightly poisonous, return Liver Channel, there is heat-clearing and toxic substances removing, reducing swelling and alleviating pain, the function of cool liver arresting convulsion, controls furuncle carbuncle, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, convulsion with spasms.Select Cortex Dictamni to be because its nature and flavor are bitter, salty, cold, enter spleen, stomach warp, dispel the wind, dampness, heat clearing away, the function of removing toxic substances, controls wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.Select Indigo Naturalis to be because its nature and flavor are salty, cold, enter liver, lung, stomach warp, there is heat clearing away, removing heat from blood, the function of removing toxic substances, controls epidemic febrile disease intenseness of heat, and macule is spitted blood, is spat blood, little Jing Epilepsy, skin ulcer is swollen, erysipelas, snake bite and insect sting.Select Mirabilitum crystallina to be because its nature and flavor are pungent salty, cold, enter the heart, stomach, kidney channel, there is resolving heat and reducing pathogenic fire, sharp key, the function of detumescence, row calentura while controlling, accumulated heat excessive thirst, vomits and diarrhoea, edema, urine retention, bleeding from the gum, erysipelas, scalds.Select Herba Taraxaci to be because its property bitter but sweet flavor is cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Radix Cynanchi Atrati to be because its nature and flavor hardship is salty, cold, enter lung, stomach, kidney channel, have heat clearing away, the function of removing heat from blood, controls yin asthenia generating intrinsic heat, the scorching hot hypersomnia of rheumatism, lung-heat hemoptysis, pyrexial malaria, intermittent high fever, puerperal fidgets due to deficiency syncope due to excessive bleeding, pyretic stranguria, stranguria with blood, rheumatalgia, scrofula.Selecting Herba Violae is that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because of its nature and flavor bitter, acrid, cold, and the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Select Rhizoma Et Radix Notopterygii to be because its nature and flavor are arduous, temperature, enters bladder, kidney channel, has loose exterior cold, wind-damp dispelling, and the function in sharp joint, the wind and cold that cures cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.Select Radix Isatidis to be because its nature and flavor are bitter, cold, enter liver, stomach blood system, there is heat clearing away, removing toxic substances, the function of removing heat from blood, controls influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, pyretic toxicity is sent out speckle, and coma is told nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash.Select Pericarpium Zanthoxyli to be because its nature and flavor are pungent, temperature, poisonous, enter spleen, lung, kidney channel, there is warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separate fish raw meat poison, control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, and cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies.Select Herba Equiseti Hiemalis to be because its nature and flavor sweetness and bitterness is flat, enter lung, liver, gallbladder meridian, have wind-dispelling heat-dissipating, expelling pathogenic factors from muscles, the function of nebula removing, controls the raw nebula of order, epiphora induced by wind, discharging fresh blood stool, dysentery, proctoptosis, malaria, laryngalgia, carbuncle.Select Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, enter lung, large intestine channel, there is expelling phlegm for arresting cough, to relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Select Radix Curcumae to be because its nature and flavor are arduous, cool, enter the heart, lung, Liver Channel, have circulation of qi promoting solution with, the function of removing heat from blood removing blood stasis with potent drugs, controls all pains of breast abdomen side of body rib, loses the heart demented, calentura coma, spits blood, epistaxis, hematuria, stranguria with blood, women's vicarious menstruation, jaundice.Select Fructus Gardeniae to be because its nature and flavor are bitter, cold, enter the heart, liver, lung, stomach warp, there is heat clearing away, pathogenic fire purging, the function of removing heat from blood, controls calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quenches one's thirst, conjunctival congestion, pharyngalgia, spits blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.Select Fructus Leonuri to be because its nature and flavor are sweet pungent, cool, enter heart born of the same parents, Liver Channel, have promoting blood flow to regulate menstruation, the function of wind and heat dispersing, controls menoxenia, metrorrhagia leukorrhagia, and postnatal blood stasis is had a pain, liver-heat headache, conjunctival congestion and swelling pain, or raw nebula film.Select Gypsum Fibrosum to be because its property acrid-sweet flavor is cold, enter lung, stomach warp, raw with there being expelling pathogenic factors from muscles for clearing heat, the function that relieving restlessness is quenched the thirst, controls calentura high fever and does not move back, vexed coma, delirium is gone mad, thirsty and dry pharynx, lung-heat dyspnea with rapid respiration, heatstroke spontaneous perspiration, stomach-fire headache, toothache, hyperactivity of toxic heat, send out speckle dermexanthesis, aphtha of the mouth and tongue, forges deposited promoting tissue regeneration and ulcer healing, external treatment ulcer sores, bursts and does not regain, the burning hot wound of soup.Select Flos Lonicerae to be because its nature and flavor are sweet, cold, enter lung, stomach warp, there is heat clearing away, the function of removing toxic substances, controls epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle and ulcer, toxic swelling, scrofula, anal fistula.Select Rhizoma Coptidis to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, there is pathogenic fire purging, dampness, removing toxic substances, the function of parasite killing, row pyretic toxicity, typhoid fever while controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis, tells, nosebleed, hematochezia, quenches one's thirst, and infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Selecting Fructus Tribuli is because its nature and flavor toil, and temperature, enters liver, lung meridian, has loose wind, improving eyesight, and the therapeutic method to keep the adverse QI flowing downwards, the function of promoting the circulation of blood, controls headache, itching over the body, the conjunctival congestion nebula that swell, fullness in the chest, cough with dyspnea , mass in the abdomen, breast difficulty, carbuncle, scrofula.Select Herba Setariae Viridis to be because its nature and flavor are cool, light, have heat extraction, dry, the function of detumescence, controls carbuncle, skin ulcer tinea, acute conjunctivitis.Select Rhizoma Phragmitis to be because its nature and flavor are sweet, cold, enter lung, stomach warp, has heat clearing away, promotes the production of body fluid, relieving restlessness, the function of preventing or arresting vomiting, controls calentura excessive thirst, and gastropyretic vomiting is dysphagic, regurgitation, consumptive lung disease, lung abscess, and separate Fugu ocellatus ichthyotoxin.Select Pseudobulbus Bletillae (Rhizoma Bletillae) to be because its property bitter but sweet flavor is cool, enter lung meridian, have tonifying the lung, hemostasis, detumescence, raw sight, the function of sore, controls lung and hinders hemoptysis, epistaxis, incised wound is hemorrhage, swollen ulcer drug, ulcer pain, soup fire is burnt, rhagadia manus et pedis.Select Cortex Moutan to be because its nature and flavor are arduous, cool, enter the heart, liver, kidney channel, have heat clearing away, removing heat from blood, and blood, the function of repercussive, controls the pathogenic heat attacking blood system in febrile diseases, sends out speckle , Jing Epilepsy, and tell, be defeated in battle, have blood in stool, hectic fever due to YIN-deficiency consumptive fever, amenorrhea , mass in the abdomen, carbuncle and ulcer, flutters damage.Select Spica Prunellae to be because its nature and flavor toil is cold, enter liver, gallbladder meridian, have liver heat removing, the function of eliminating stagnation, controls scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia is shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia.Select Herba Erodii to be because its nature and flavor toil is dispeled the wind, invigorate blood circulation, the function of heat-clearing and toxic substances removing, dispelling the wind and dampness pathogens pain, contracture is numb, carbuncle, traumatic injury, enteritis, dysentery.Select Mel to be because its nature and flavor are sweet, flat, enter lung, spleen, large intestine channel, there is invigorating middle warmer, moisturize, pain relieving, the function of removing toxic substances, controls xeropulmonary cough, dryness of the intestine constipation, gastralgia, nasal sinusitis, aphtha, the burning hot wound of soup, separates Aconitum Carmichaeli.
The specific embodiment
The drug dose of the present invention's combination is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Herba Asari 8-15 gram of Flos Chrysanthemi 8-15 gram of Periostracum Cicadae 8-15 gram
Fructus Arctii 8-15 gram of Fructus Kochiae 8-15 gram of Flos Eriocauli 8-15 gram
Spora Lygodii 10-20 gram of Herba Schizonepetae 8-15 gram of Zaocys 6-10 gram
Herba Centipedae 8-15 gram of Semen Cassiae 6-10 gram of Cortex Fraxini 8-15 gram
Rhizoma Paridis 8-15 gram of Cortex Dictamni 8-15 gram of Indigo Naturalis 8-15 gram
Mirabilitum crystallina 6-10 gram of Herba Taraxaci 8-15 gram of Radix Cynanchi Atrati 8-15 gram
Herba Violae 8-15 gram of Rhizoma Et Radix Notopterygii 6-10 gram of Radix Isatidis 15-20 gram
Pericarpium Zanthoxyli 6-10 gram of Herba Equiseti Hiemalis 8-15 gram of Semen Armeniacae Amarum 8-15 gram
Radix Curcumae 8-15 gram of Fructus Gardeniae 8-15 gram of Fructus Leonuri 8-15 gram
Gypsum Fibrosum 3-6 gram of Flos Lonicerae 8-15 gram of Rhizoma Coptidis 6-10 gram
Fructus Tribuli 8-15 gram of Herba Setariae Viridis 8-15 gram of Rhizoma Phragmitis 8-15 gram
Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15 gram of Cortex Moutan 8-15 gram of Spica Prunellae 8-15 gram
Herba Erodii 10-20 gram of Mel 6-15 gram
Preferable amount is
10 grams of 10 grams of Periostracum Cicadaes of 10 grams of Flos Chrysanthemis of Herba Asari
10 grams of 10 grams of Flos Eriocaulis of 10 grams of Fructus Kochiae of Fructus Arctii
8 grams of 10 grams of Zaocyss of 15 grams of Herba Schizonepetae of Spora Lygodii
10 grams of 8 grams of Cortex Fraxinis of 10 grams of Semen Cassiaes of Herba Centipedae
10 grams of 10 grams of Indigo Naturaliss of 10 grams of Cortex Dictamni of Rhizoma Paridis
10 grams of 10 grams of Radix Cynanchi Atratis of 8 grams of Herba Taraxacis of Mirabilitum crystallina
18 grams of 8 grams of Radix Isatidis of 10 grams of Rhizoma Et Radix Notopterygiis of Herba Violae
10 grams, 10 grams of Semen Armeniacae Amarums of 8 grams of Herba Equiseties Hiemalis of Pericarpium Zanthoxyli
12 grams of 10 grams of Fructus Leonuris of 10 grams of Fructus Gardeniaes of Radix Curcumae
6 grams of 10 grams of Rhizoma Coptidis of 5 grams of Flos Loniceraes of Gypsum Fibrosum
10 grams of 10 grams of Rhizoma Phragmitiss of 10 grams of Herba Setariae Viridis of Fructus Tribuli
10 grams of 10 grams of Spica Prunellaes of 10 grams of Cortex Moutans of Pseudobulbus Bletillae (Rhizoma Bletillae)
10 grams of 15 grams of Mel of Herba Erodii
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Herba Asari: Ex-all impurity, water spray profit, cutting in time, dries;
2, Flos Chrysanthemi: choose clean leaf stalk, anthocaulus and spare impurity;
3, Periostracum Cicadae: choose decontamination, clean and dry;
4, Fructus Arctii: choose decontamination, sieve removes spare;
5, the Fructus Kochiae: get crude drug, remove impurity, sieve removes chip;
6, Flos Eriocauli: remove sheath, impurity, cutting;
7, Spora Lygodii: get crude drug, cross dusting cover, sieve is got spore, removes impurity;
8, Herba Schizonepetae: choose clean impurity, water is bubble slightly, pulls cutting out, dries;
9, Zaocys: get crude drug, brush away ash bits, the used time decaptitates, squama, cutting;
10, Herba Centipedae: choose clean impurity, cutting, dries;
11, Semen Cassiae: get clean Semen Cassiae, put in pot and fry extremely micro-fragrance that has, take out, cool;
12, Cortex Fraxini: choose decontamination, clean, run through rear stripping and slicing or cutting, dry;
13, Rhizoma Paridis: remove fibrous root, cleaning, drying;
14, Cortex Dictamni: choose clean impurity, remove rough bark, clean, slightly profit, cuts into slices, and dries;
15, Indigo Naturalis: choose decontamination, sieve;
16, Mirabilitum crystallina: get crude drug, remove impurity, cleaning, drying, break into fragment;
17, Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
18, Radix Cynanchi Atrati: choose clean impurity, remove stem Seedling, clean, slightly soak, run through, cutting, dries;
19, Herba Violae: get crude drug, remove impurity, clean, slightly dry in the air, cutting, dry;
20, Rhizoma Et Radix Notopterygii: choose decontamination, clean, run through, section, dries;
21, Radix Isatidis: choose clean impurity, clean, run through, section, dries;
22, Pericarpium Zanthoxyli: remove fruit stem and seed, Semen zanthoxyli, put pot interior stir-fry to making sound, take out, cool;
23, Herba Equiseti Hiemalis: clean, slightly profit, cuts off root, and cutting, dries;
24, Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, pull out when the micro-wrinkle of crust, soak in cold water, slough kind of a skin, dry, winnow with a dustpan clean;
25, Radix Curcumae: be soaked in water, clean, pull out to shine and dry in the air, run through, section, dries;
26, Fructus Gardeniae: sieve dedust bits, choose decontamination, pulverize and sieve or cut off two ends;
27, Fructus Leonuri: extract Herb during fruit maturation, dry, lay fruit, choose debranching leaf, well sifted impurity;
28, Gypsum Fibrosum: remove assorted stone, clean earth, be broken into fritter;
29, Flos Lonicerae: sieve removes silt, chooses clean impurity;
30, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dries in the shade;
31, Fructus Tribuli: float silt, the hard thorn that Ex-all is residual;
32, Herba Setariae Viridis: summer, autumn gather, and dry;
33, Rhizoma Phragmitis: choose decontamination and root, cutting, dries;
34, Pseudobulbus Bletillae (Rhizoma Bletillae): choose decontamination, be soaked in water, pull out, dry in the air even to inside and outside humidity, section, dry;
35, Cortex Moutan: choose decontamination, remove core, clean, run through, section, dries;
36, Spica Prunellae: get crude drug, except discarding stalk, blade and impurity, sieve dedust bits;
37, Herba Erodii: choose decontamination, remove undesirable root, wash, pull out, cutting, dries;
38, Mel: get pure Mel, temper with slow fire, filter skimming.
Two, preparation
1, by the Herba Asari of described weight, Flos Chrysanthemi, Periostracum Cicadae, Fructus Arctii, the Fructus Kochiae, Flos Eriocauli, Spora Lygodii, Herba Schizonepetae, Zaocys, Herba Centipedae, Semen Cassiae, Cortex Fraxini, Rhizoma Paridis, Cortex Dictamni, Indigo Naturalis, Mirabilitum crystallina, Herba Taraxaci, Radix Cynanchi Atrati, Herba Violae, Rhizoma Et Radix Notopterygii, Radix Isatidis, Pericarpium Zanthoxyli, Herba Equiseti Hiemalis, Semen Armeniacae Amarum, Radix Curcumae, Fructus Gardeniae, Fructus Leonuri, Gypsum Fibrosum, Flos Lonicerae, Rhizoma Coptidis, Fructus Tribuli, Herba Setariae Viridis, Rhizoma Phragmitis, Pseudobulbus Bletillae (Rhizoma Bletillae), Cortex Moutan, Spica Prunellae, Herba Erodii, Mel decocts with water twice, add for the first time 6 times of amounts of water, intense fire decocts boiling 10 minutes, use again slow fire boiling 30 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.
2, will filter for the first time rear medicinal residues and add 4 times of amounts of water, and decoct boiling, then within 20 minutes, obtain decoction liquor for the second time with slow fire boiling.
3, twice decoction liquor mixed, intense fire decocts, then with slow fire boiling 10 minutes and get final product, decoction liquor is divided into 6 doses and takes.
Medicine of the present invention has heat clearing away, removing toxic substances, and liver heat removing, improving eyesight, the effect of diuretic, treatment catarrhal conjunctivitis instant effect, short treating period, do not recur.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.4kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 235 examples for medical treatment.
2, diagnostic criteria
1. wind overweights pattern of fever
Patient's blepharoedema, hyperemia of the bulbar conjunctiva, sufferings double as, the many tear of photophobia, headache nasal obstruction, fever with aversion to wind.
2. hanker after wind type
Show as white of the eye edema, more very, born of the same parents' eyelid is red and swollen for swelling pain, and hot tears are as soup, adversion to heat and photophobia, thirsty yellowish urine.
3. wind heat is also heavy
Disease sees that white of the eye is red heavy, and sufferings have concurrently, aversion to cold photophobia, headache nasal obstruction, heating, thirst with desire to drink, constipation dark coloured urine.With the passing of time lose the person of controlling, can change into chronic.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day, early, middle and late respectively clothes 1 time, 5 days was a course for the treatment of, took continuously 4 courses for the treatment of.
4, efficacy assessment standard
Effective: catarrhal conjunctivitis is eliminated, observe after half a year without recurrence;
Take a turn for the better: catarrhal conjunctivitis symptom is clearly better;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, by Drug therapy catarrhal conjunctivitis patient of the present invention 235 examples, effective 223 examples of result, obvious effective rate is 94.9%, 8 examples that take a turn for the better, and improvement rate is 3.4%, invalid 4 examples, total effective rate is 98.3%.