CN103638495A - Medicament for treating paranasal sinusitis and preparation method of medicament - Google Patents

Medicament for treating paranasal sinusitis and preparation method of medicament Download PDF

Info

Publication number
CN103638495A
CN103638495A CN201310663476.9A CN201310663476A CN103638495A CN 103638495 A CN103638495 A CN 103638495A CN 201310663476 A CN201310663476 A CN 201310663476A CN 103638495 A CN103638495 A CN 103638495A
Authority
CN
China
Prior art keywords
grams
gram
herba
clean
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201310663476.9A
Other languages
Chinese (zh)
Other versions
CN103638495B (en
Inventor
张朝兰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201310663476.9A priority Critical patent/CN103638495B/en
Publication of CN103638495A publication Critical patent/CN103638495A/en
Application granted granted Critical
Publication of CN103638495B publication Critical patent/CN103638495B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicament for treating paranasal sinusitis and a preparation method of the medicament. The medicament is mainly prepared from medicines such as magnolia flower, lotus rhizoma node, artemisia capillaries, fructus viticis, antelope horn, radix semiaquilegiae, houttuynia cordata, cassia twig and the like according to a certain weight ratio. The medicament disclosed by the invention has the functions of clearing away heat and toxic materials and dispelling the wind and removing stasis, and is rapid to take an effect, good in curative effect, free of reoccurrence and free of side effect when used for treating paranasal sinusitis.

Description

A kind of medicine for the treatment of nasal sinusitis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of nasal sinusitis and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Nasal sinusitis comprises acute rhinosinusitis and chronic paranasal rhinitis.Sinusitis is also referred to as nasal sinusitis, Wei Bi section common disease, and chronic person is in the majority.Front group of nasal sinuses is high compared with the sickness rate of posterior nasal sinuses, and wherein maxillary sinus is the most common.Sinusitis can betide a side, also can bilateral.A hole morbidity can be limited to, also many holes can be involved.If the whole nasal sinuses in one or both sides is all fallen ill, be " entirely organizing sinusitis ".At present, because Western medicine cannot effectively be treated nasal sinusitis, and long-term taking Western medicine has certain side effect, and therefore, people exist very large demand to the Chinese medicine of rapid, effective treatment nasal sinusitis.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical test and checking repeatedly, has finally found the medicine of effective treatment nasal sinusitis, thereby has completed the present invention.
Object of the present invention is just to provide a kind of composition of medicine that can effectively treat nasal sinusitis.
Another object of the present invention has just been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects Flos Magnoliae, Nodus Nelumbinis Rhizomatis, Herba Artemisiae Scopariae, Fructus Viticis, Cornu Saigae Tataricae, Radix Semiaquilegiae, Herba Houttuyniae, Ramulus Cinnamomi, Herba Menthae, Herba Violae, Bulbus Lilii, Fructus Liquidambaris, Radix Trichosanthis, Concretio Silicea Bambusae, Fructus Amomi Rotundus, Rhizoma Zingiberis Recens, Bombyx Batryticatus, Folium Camelliae sinensis, Semen Armeniacae Amarum, Radix Achyranthis Bidentatae, Herba Taraxaci, Cortex Albiziae, Folium Isatidis, Rhizoma Acori Graminei, Spina Gleditsiae, Semen Coicis, Caulis Akebiae, Herba Houttuyniae, Rhizoma Phragmitis, Radix Scrophulariae medicine to combine, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can fast treating nasal sinusitis.Wherein select Flos Magnoliae to be because its nature and flavor are pungent, temperature, enters lung, stomach warp, dispels the wind, and sensible function, controls headache, and nasal sinusitis is had a stuffy nose obstructed, toothache.Select Nodus Nelumbinis Rhizomatis to be because its property sweet-puckery flavor is flat, few the moon of starting with, foot sun is bright, and JUE YIN meridian, has hemostasis, and the function of dissipating blood stasis, controls hemoptysis, spits blood, epistaxis, hematuria, has blood in stool, dysentery, metrorrhagia.Select Herba Artemisiae Scopariae to be because its nature and flavor toil is cool, enter liver, spleen, urinary bladder channel, have the function of clearing away heat-damp and promoting diuresis, control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Selecting Fructus Viticis is because its nature and flavor toil, cool, enters liver, stomach, and urinary bladder channel, has dispelling wind and heat pathogens, and the clear sharp head's function, controls anemopyretic cold, just, migraine, and toothache, pain in order eyeball.Select Cornu Saigae Tataricae to be because its nature and flavor are salty, cold, enter liver, heart channel, there is suppressing the hyperactive liver to relieve the wind syndrome, heat clearing away is relieving convulsion, and the function of removing toxic substances is controlled calentura coma convulsion and is fainted, and delirium is gone mad, and the dizzy , Jing Epilepsy of having a headache is twitched, conjunctivitis.Select Radix Semiaquilegiae to be because its nature and flavor sweetness and bitterness is cold, enter spleen, small intestinal, bladder three warps, have heat clearing away, removing toxic substances, detumescence, eliminating stagnation, the function of diuresis, controls carbuncle, scrofula, furuncle, stranguria with turbid discharge, leukorrhagia, cough due to deficiency of the lung, hernia , epilepsy, infantile convulsion, hemorrhoid, traumatic injury.Select Herba Houttuyniae to be because its nature and flavor are pungent, cold, enter meridian of Hand-TAI YIN, there is heat-clearing and toxic substances removing, the function of inducing diuresis to remove edema, controls pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.Selecting Ramulus Cinnamomi is that temperature, enters bladder, the heart, lung meridian, has diaphoresis expelling pathogenic factors from muscles because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation, controls exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Select Herba Menthae to be because its nature and flavor are pungent, cool, enter lung, Liver Channel, have dispelling wind, heat radiation, wards off dirtyly, and the function of removing toxic substances, controls affection due to external wind and heat, headache, conjunctival congestion, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria.Selecting Herba Violae is that GUIXIN, Liver Channel, have heat-clearing and toxic substances removing because of its nature and flavor bitter, acrid, cold, and the function of removing heat from blood detumescence, controls furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Select Bulbus Lilii to be because its property sweet and slightly bitter taste is flat, enter the heart, lung meridian, have nourishing the lung to arrest cough, the function of clearing away heart-fire for tranquillization, controls pulmonary tuberculosis chronic cough, cough and spit expectorant blood, and after calentura, waste heat is unclear, fidgets due to deficiency palpitation with fear, staring spells, beriberi edema.Select Fructus Liquidambaris to be because its nature and flavor are bitter flat, current 12 warps, have dispelling wind and removing obstruction in the collateral, and the function of promoting urination to remove dampness, harnesses the river swollen, distension, and amenorrhea, breast is few, contracture of the limbs.Select Radix Trichosanthis to be because its nature and flavor sweetness and bitterness acid is cool, enter lung, stomach warp, have and promote the production of body fluid, quench the thirst, pathogenic fire reducing, moisturizes, evacuation of pus, and the function of detumescence, controls calentura thirsty, quenches one's thirst, jaundice, dryness of the lung hemoptysis, carbuncle, hemorrhoid complicated by anal fistula.Select Concretio Silicea Bambusae to be because its nature and flavor are sweet, GUIXIN, Liver Channel, have clear heat and eliminate phlegm, and the function of cool heart arresting convulsion, controls calentura coma, middle wind-phlegm fan, and the hot infantile convulsion of children's's expectorant, twitches, night cry.Select Fructus Amomi Rotundus be because its nature and flavor pungent, temperature, enters lung, spleen channel, has sector-style, warming the stomach, helps digestion, the function of alleviating distention in middle-JIAO, controls the stagnation of QI, dyspepsia is uncomfortable in chest, abdominal distention, eructation, dysphagic, tell contrary, regurgitation, malaria.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enters lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting, opens the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Bombyx Batryticatus to be because its nature and flavor are pungent, salty, flat, return liver, lung meridian.Expelling wind to relieve convulsion, dissipating phlegm and resolving masses.For apoplexy facial hemiparalysis, infantile convulsion is twitched, and head is grant, sore throat, scrofula tuberculosis, rubella erysipelas.Select Folium Camelliae sinensis to be because its property bitter but sweet flavor, cool.Enter the heart, lung, stomach warp.Refresh oneself, relieving thirst and restlessness, reduces phlegm, helps digestion, diuresis, removing toxic substances.Control headache, blurred vision, kind the sleeping of sleeping more, restlessness and thirst, food stagnation expectorant is stagnant, malaria, dysentery.Select Semen Armeniacae Amarum to be because its nature and flavor are bitter, temperature, poisonous, enter lung, large intestine channel, there is expelling phlegm for arresting cough, to relieving asthma, the function of intestine moistening, controls exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and the function of subduing inflammation, controls gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury, ripe in invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select Herba Taraxaci to be because its property bitter but sweet flavor is cold, enter liver, stomach warp, have heat-clearing and toxic substances removing, the function of diuresis eliminating stagnation, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.Select Cortex Albiziae to be because its nature and flavor are sweet, flat, enter the heart, Liver Channel, there is resolving depression, and blood, mind calming, the function of subduing inflammation, controls irritability, melancholy insomnia, lung abscess, carbuncle, scrofula, injured bone.Select Folium Isatidis to be because its nature and flavor are bitter, cold, enter liver, the heart, stomach warp, there is heat clearing away, removing toxic substances, removing heat from blood, the function of hemostasis, controls epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas, spits blood, epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Select Rhizoma Acori Graminei to be because its nature and flavor are arduous, tepor, enters the heart, liver, spleen channel, has and has one's ideas straightened out, and eliminating phlegm, regulates the flow of vital energy, and invigorates blood circulation, loose wind, the function of drying, Zhi epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Select Spina Gleditsiae to be because its nature and flavor are pungent, temperature, searches wind, draw out pus by applying a plaster to the affected part, and detumescence, the function of evacuation of pus, controls carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Select Semen Coicis to be because its property slightly sweet flavor is cool, enter spleen, lung, kidney channel, have spleen invigorating, tonifying the lung, heat clearing away, the function of dampness removing, controls and has loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.Select Caulis Akebiae to be because its nature and flavor are bitter, cool, enter the heart, small intestinal, urinary bladder channel, have pathogenic fire purging row water, the function of promoting blood circulation, controls hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.Select Herba Houttuyniae to be because its nature and flavor are pungent, cold, enter meridian of Hand-TAI YIN, there is heat-clearing and toxic substances removing, the function of inducing diuresis to remove edema, controls pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, tinea alba, scabies.Select Rhizoma Phragmitis to be because its nature and flavor are sweet, cold, enter lung, stomach warp, has heat clearing away, promotes the production of body fluid, relieving restlessness, the function of preventing or arresting vomiting, controls calentura excessive thirst, and gastropyretic vomiting is dysphagic, regurgitation, consumptive lung disease, lung abscess, and separate Fugu ocellatus ichthyotoxin.Select Radix Scrophulariae to be because its nature and flavor are bitter, salty, cool, enter lung, kidney channel, have YIN nourishing, pathogenic fire reducing, relieving restlessness, the function of removing toxic substances, controls calentura excessive thirst, sends out speckle, and hectic fever due to YIN-deficiency consumptive fever, sleeps not peaceful night, spontaneous sweating, constipation is hindered in Tianjin, hematemesis and epistaxis, laryngopharynx swelling and pain, carbuncle, scrofula.
The specific embodiment
The drug dose of component of the present invention is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect within the scope of following weight
Flos Magnoliae 25-35 gram of Nodus Nelumbinis Rhizomatis 10-20 gram of Herba Artemisiae Scopariae 5-15 gram
Fructus Viticis 10-20 gram of Cornu Saigae Tataricae 5-15 gram of Radix Semiaquilegiae 5-15 gram
Herba Houttuyniae 10-20 gram of Ramulus Cinnamomi 15-25 gram of Herba Menthae 25-35 gram
Herba Violae 25-35 gram of Bulbus Lilii 15-25 gram of Fructus Liquidambaris 10-20 gram
Radix Trichosanthis 10-20 gram of Concretio Silicea Bambusae 10-15 gram of Fructus Amomi Rotundus 10-20 gram
Rhizoma Zingiberis Recens 5-15 gram of Bombyx Batryticatus 10-20 gram of Folium Camelliae sinensis 8-15 gram
Semen Armeniacae Amarum 5-15 gram of Radix Achyranthis Bidentatae 10-20 gram of Herba Taraxaci 5-15 gram
Cortex Albiziae 25-35 gram of Folium Isatidis 10-15 gram of Rhizoma Acori Graminei 10-20 gram
Spina Gleditsiae 3-9 gram of Semen Coicis 5-15 gram of Caulis Akebiae 25-35 gram
Herba Houttuyniae 25-35 gram of Rhizoma Phragmitis 3-9 gram of Radix Scrophulariae 3-9 gram
Preferable amount is
10 grams of 15 grams of Herba Artemisiae Scopariae of 30 grams of Nodus Nelumbinis Rhizomatis of Flos Magnoliae
10 grams of 10 grams of Radix Semiaquilegiaes of 15 grams of Cornu Saigae Tataricae of Fructus Viticis
30 grams of 20 grams of Herba Menthaes of 15 grams of Ramulus Cinnamomi of Herba Houttuyniae
15 grams of 20 grams of Fructus Liquidambaris of 30 grams of Bulbus Liliies of Herba Violae
15 grams of 12 grams of Fructus Amomi Rotunduss of 15 grams of Concretio Silicea Bambusaes of Radix Trichosanthis
10 grams of 15 grams of Folium Camelliae sinensis of 10 grams of Bombyx Batryticatus of Rhizoma Zingiberis Recens
10 grams of 15 grams of Herba Taraxacis of 10 grams of Radix Achyranthis Bidentataes of Semen Armeniacae Amarum
15 grams of 12 grams of Rhizoma Acori Graminei of 30 grams of Folium Isatidiss of Cortex Albiziae
30 grams of 10 grams of Caulis Akebiaes of 6 grams of Semen Coiciss of Spina Gleditsiae
6 grams of 6 grams of Radix Scrophulariaes of 30 grams of Rhizoma Phragmitiss of Herba Houttuyniae
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Flos Magnoliae: choose clean branch stalk impurity, smash use to pieces;
2, Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and to be black to outside, inside is strong yellow, slightly spills clear water, takes out, dry;
3, Herba Artemisiae Scopariae: sieve, choose decontamination, remove undesirable root, pulverize, remove spare after sieve;
4, Fructus Viticis: well sifted ash bits, remove remaining sepal, put in pot and fry with high heat to coke yellow, slightly spray clear water, cool;
5, Cornu Saigae Tataricae: except the plug of boning, enter in water after dipping, pull muscle out, the longitudinal thin slice of pound one-tenth, dries;
6, Radix Semiaquilegiae: clear water is cleaned, section, dries;
7, Herba Houttuyniae: remove impurity, remove undesirable root, clean cutting, dry;
8, Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
9, Herba Menthae: choose clean impurity, remove undesirable root, first leaf is trembled and separately put down, then stem is sprayed to clear water, run through rear cutting, dry, then with leaf and even;
10, Herba Violae: get crude drug, remove impurity, clean, slightly dry in the air, cutting, dry;
11, Bulbus Lilii: choose decontamination, black lobe, the ash disposal of winnowing with a dustpan bits;
12, Fructus Liquidambaris: remove impurity, clean, dry;
13, Radix Trichosanthis: choose decontamination, size block separately, saturating with blister approximately sixty percent, pulls out, and moistening is even to inside and outside humidity, and section, dries, or wash, and pulls out, shines extremely dryly, smashes into fritter;
14, Concretio Silicea Bambusae: get crude drug, remove impurity, ash bits;
15, Fructus Amomi Rotundus: choose clean impurity, sieve scurf removing, smashes, or peel off shell, gets core and smashes use;
16, Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
17, Bombyx Batryticatus: get crude drug, remove residual silk, impurity;
18, Folium Camelliae sinensis: get crude drug, remove impurity, branch stalk;
19, Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, pull out when the micro-wrinkle of crust, soak in cold water, slough kind of a skin, dry, winnow with a dustpan clean;
20, Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
21, Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
22, Cortex Albiziae: clear water soak to be cleaned, and pulls out, is first divided into after moistening and equates large rectangular, then stripping and slicing or shredding, dry;
23, Folium Isatidis: choose decontamination and dead leaf, clean, slightly moisten, cutting, dries;
24, Rhizoma Acori Graminei: choose decontamination, clean, slightly soak, run through, section, dries;
25, Spina Gleditsiae: choose decontamination, be soaked in water, run through rear section, dry;
26, Semen Coicis: get crude drug, remove residual cot, impurity;
27, Caulis Akebiae: water slightly soaks, moistening, to thoroughly, is cut into slices, and dries;
28, Herba Houttuyniae: remove impurity, remove undesirable root, clean cutting, dry;
29, Rhizoma Phragmitis: choose decontamination and root, cutting, dries;
30, Radix Scrophulariae: choose clean impurity, except removing LU, clean and run through, section, dries.
Two, preparation
The Flos Magnoliae of described weight, Nodus Nelumbinis Rhizomatis, Herba Artemisiae Scopariae, Fructus Viticis, Cornu Saigae Tataricae, Radix Semiaquilegiae, Herba Houttuyniae, Ramulus Cinnamomi, Herba Menthae, Herba Violae, Bulbus Lilii, Fructus Liquidambaris, Radix Trichosanthis, Concretio Silicea Bambusae, Fructus Amomi Rotundus, Rhizoma Zingiberis Recens, Bombyx Batryticatus, Folium Camelliae sinensis, Semen Armeniacae Amarum, Radix Achyranthis Bidentatae, Herba Taraxaci, Cortex Albiziae, Folium Isatidis, Rhizoma Acori Graminei, Spina Gleditsiae, Semen Coicis, Caulis Akebiae, Herba Houttuyniae, Rhizoma Phragmitis, Radix Scrophulariae medicine are added to 8 times of amounts of water, soak 200 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 35 minutes, filter to obtain decoction liquor for the first time; The medicinal residues of filtration are added to 6 times of amounts of water, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time; Merge secondary decoction liquor, intense fire boils, then with slow fire boiling 10 minutes and get final product, decoction liquor is divided into 4 doses and takes.
Medicine of the present invention has heat clearing away, and removing toxic substances, dispels the wind, sensible effect, and treatment nasal sinusitis instant effect, short treating period, do not recur.
By test example, further set forth below the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention
Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.4kg, divides two groups, and 15 every group, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, every day 2 times, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 167 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation
1. have a stuffy nose
Not etc., how, because of due to the congested swelling of nasal mucosa and secretions increase, nasal obstruction often can not cause temporary olfactory disorder to weight.
2. pus tears are many
Nasal mucus mostly is purulence or glutinous purulence, blows only, can be with a little blood in pus tears.Anaerobe or coli-infection person's pus tears stench.Pus tears can after flow to pharyngeal and throat, stimulate local mucosa to cause to itch, feel sick, cough and expectoration.
3. headache
Chronic purulent sinusitis is generally obvious local pain or headache.
4. other
Because pus tears flow into the mouth breathing of pharyngeal and long-term use, often with chronic pharyngitis symptom, as abundant expectoration, foreign body sensation or have sore throat etc.If affect pharyngotympanic tube, also can there be the symptoms such as tinnitus, deafness.
3, Therapeutic Method
Select above-mentioned medicament, to patient, take, each serving with 1 dose, every day, early, middle and late respectively clothes 1 time, 7 days was a course for the treatment of, took continuously 3 courses for the treatment of.
4, efficacy assessment standard
Effective: nasal sinusitis is eliminated, and physical recovery is normal, observe after half a year without recurrence;
Take a turn for the better: nasal sinusitis symptom is clearly better, and body constitution obviously recovers;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
Figure 2013106634769100002DEST_PATH_IMAGE001
In above-mentioned treatment, by Drug therapy nasal sinusitis patient of the present invention 167 examples, effective 160 examples of result, obvious effective rate is 95.81%, 5 examples that take a turn for the better, and improvement rate is 2.99%, invalid 2 examples, total effective rate is 98.8%.

Claims (3)

1. a medicine for the treatment of nasal sinusitis, is characterized in that: it is to be made by the crude drug in following weight range:
Flos Magnoliae 25-35 gram of Nodus Nelumbinis Rhizomatis 10-20 gram of Herba Artemisiae Scopariae 5-15 gram
Fructus Viticis 10-20 gram of Cornu Saigae Tataricae 5-15 gram of Radix Semiaquilegiae 5-15 gram
Herba Houttuyniae 10-20 gram of Ramulus Cinnamomi 15-25 gram of Herba Menthae 25-35 gram
Herba Violae 25-35 gram of Bulbus Lilii 15-25 gram of Fructus Liquidambaris 10-20 gram
Radix Trichosanthis 10-20 gram of Concretio Silicea Bambusae 10-15 gram of Fructus Amomi Rotundus 10-20 gram
Rhizoma Zingiberis Recens 5-15 gram of Bombyx Batryticatus 10-20 gram of Folium Camelliae sinensis 8-15 gram
Semen Armeniacae Amarum 5-15 gram of Radix Achyranthis Bidentatae 10-20 gram of Herba Taraxaci 5-15 gram
Cortex Albiziae 25-35 gram of Folium Isatidis 10-15 gram of Rhizoma Acori Graminei 10-20 gram
Spina Gleditsiae 3-9 gram of Semen Coicis 5-15 gram of Caulis Akebiae 25-35 gram
Herba Houttuyniae 25-35 gram of Rhizoma Phragmitis 3-9 gram of Radix Scrophulariae 3-9 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
10 grams of 15 grams of Herba Artemisiae Scopariae of 30 grams of Nodus Nelumbinis Rhizomatis of Flos Magnoliae
10 grams of 10 grams of Radix Semiaquilegiaes of 15 grams of Cornu Saigae Tataricae of Fructus Viticis
30 grams of 20 grams of Herba Menthaes of 15 grams of Ramulus Cinnamomi of Herba Houttuyniae
15 grams of 20 grams of Fructus Liquidambaris of 30 grams of Bulbus Liliies of Herba Violae
15 grams of 12 grams of Fructus Amomi Rotunduss of 15 grams of Concretio Silicea Bambusaes of Radix Trichosanthis
10 grams of 15 grams of Folium Camelliae sinensis of 10 grams of Bombyx Batryticatus of Rhizoma Zingiberis Recens
10 grams of 15 grams of Herba Taraxacis of 10 grams of Radix Achyranthis Bidentataes of Semen Armeniacae Amarum
15 grams of 12 grams of Rhizoma Acori Graminei of 30 grams of Folium Isatidiss of Cortex Albiziae
30 grams of 10 grams of Caulis Akebiaes of 6 grams of Semen Coiciss of Spina Gleditsiae
6 grams of 6 grams of Radix Scrophulariaes of 30 grams of Rhizoma Phragmitiss of Herba Houttuyniae.
3. according to the preparation method of medicine described in claim 1 or 2, it is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Flos Magnoliae: choose clean branch stalk impurity, smash use to pieces;
(2) Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and to be black to outside, inside is strong yellow, slightly spills clear water, takes out, dry;
(3) Herba Artemisiae Scopariae: sieve, choose decontamination, remove undesirable root, pulverize, remove spare after sieve;
(4) Fructus Viticis: well sifted ash bits, remove remaining sepal, put in pot and fry with high heat to coke yellow, slightly spray clear water, cool;
(5) Cornu Saigae Tataricae: except the plug of boning, enter in water after dipping, pull muscle out, the longitudinal thin slice of pound one-tenth, dries;
(6) Radix Semiaquilegiae: clear water is cleaned, section, dries;
(7) Herba Houttuyniae: remove impurity, remove undesirable root, clean cutting, dry;
(8) Ramulus Cinnamomi: water slightly soaks, pulls out, and moistening, to thoroughly, is cut into slices, and dries, and sieves anti-dandruff;
(9) Herba Menthae: choose clean impurity, remove undesirable root, first leaf is trembled and separately put down, then stem is sprayed to clear water, run through rear cutting, dry, then with leaf and even;
(10) Herba Violae: get crude drug, remove impurity, clean, slightly dry in the air, cutting, dry;
(11) Bulbus Lilii: choose decontamination, black lobe, the ash disposal of winnowing with a dustpan bits;
(12) Fructus Liquidambaris: remove impurity, clean, dry;
(13) Radix Trichosanthis: choose decontamination, size block separately, saturating with blister approximately sixty percent, pulls out, and moistening is even to inside and outside humidity, and section, dries, or wash, and pulls out, shines extremely dryly, smashes into fritter;
(14) Concretio Silicea Bambusae: get crude drug, remove impurity, ash bits;
(15) Fructus Amomi Rotundus: choose clean impurity, sieve scurf removing, smashes, or peel off shell, gets core and smashes use;
(16) Rhizoma Zingiberis Recens: choose decontamination, clean earth, used time section;
(17) Bombyx Batryticatus: get crude drug, remove residual silk, impurity;
(18) Folium Camelliae sinensis: get crude drug, remove impurity, branch stalk;
(19) Semen Armeniacae Amarum: choose clean impurity, put in boiling water and slightly boil, pull out when the micro-wrinkle of crust, soak in cold water, slough kind of a skin, dry, winnow with a dustpan clean;
(20) Radix Achyranthis Bidentatae: choose decontamination, clean, soften, go reed, cutting, dries;
(21) Herba Taraxaci: choose decontamination, clean earth, cutting, dries;
(22) Cortex Albiziae: clear water soak to be cleaned, and pulls out, is first divided into after moistening and equates large rectangular, then stripping and slicing or shredding, dry;
(23) Folium Isatidis: choose decontamination and dead leaf, clean, slightly moisten, cutting, dries;
(24) Rhizoma Acori Graminei: choose decontamination, clean, slightly soak, run through, section, dries;
(25) Spina Gleditsiae: choose decontamination, be soaked in water, run through rear section, dry;
(26) Semen Coicis: get crude drug, remove residual cot, impurity;
(27) Caulis Akebiae: water slightly soaks, moistening, to thoroughly, is cut into slices, and dries;
(28) Herba Houttuyniae: remove impurity, remove undesirable root, clean cutting, dry;
(29) Rhizoma Phragmitis: choose decontamination and root, cutting, dries;
(30) Radix Scrophulariae: choose clean impurity, except removing LU, clean and run through, section, dries;
(2) preparation
The Flos Magnoliae of described weight, Nodus Nelumbinis Rhizomatis, Herba Artemisiae Scopariae, Fructus Viticis, Cornu Saigae Tataricae, Radix Semiaquilegiae, Herba Houttuyniae, Ramulus Cinnamomi, Herba Menthae, Herba Violae, Bulbus Lilii, Fructus Liquidambaris, Radix Trichosanthis, Concretio Silicea Bambusae, Fructus Amomi Rotundus, Rhizoma Zingiberis Recens, Bombyx Batryticatus, Folium Camelliae sinensis, Semen Armeniacae Amarum, Radix Achyranthis Bidentatae, Herba Taraxaci, Cortex Albiziae, Folium Isatidis, Rhizoma Acori Graminei, Spina Gleditsiae, Semen Coicis, Caulis Akebiae, Herba Houttuyniae, Rhizoma Phragmitis, Radix Scrophulariae medicine are added to 8 times of amounts of water, soak 200 minutes, intense fire decocts boiling 10 minutes, use again slow fire boiling 35 minutes, filter to obtain decoction liquor for the first time; The medicinal residues of filtration are added to 6 times of amounts of water, and intense fire boils, then uses slow fire boiling 20 minutes, filters to obtain decoction liquor for the second time; Merge secondary decoction liquor, intense fire boils, then with slow fire boiling 10 minutes and get final product, decoction liquor is divided into 4 doses and takes.
CN201310663476.9A 2013-12-10 2013-12-10 Medicament for treating paranasal sinusitis and preparation method of medicament Expired - Fee Related CN103638495B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310663476.9A CN103638495B (en) 2013-12-10 2013-12-10 Medicament for treating paranasal sinusitis and preparation method of medicament

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310663476.9A CN103638495B (en) 2013-12-10 2013-12-10 Medicament for treating paranasal sinusitis and preparation method of medicament

Publications (2)

Publication Number Publication Date
CN103638495A true CN103638495A (en) 2014-03-19
CN103638495B CN103638495B (en) 2015-04-08

Family

ID=50243867

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310663476.9A Expired - Fee Related CN103638495B (en) 2013-12-10 2013-12-10 Medicament for treating paranasal sinusitis and preparation method of medicament

Country Status (1)

Country Link
CN (1) CN103638495B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105412705A (en) * 2015-12-26 2016-03-23 卢文华 Medicine for treating acute nasosinusitis and preparation method thereof
CN112438387A (en) * 2019-09-02 2021-03-05 五原县金麦提升科技有限公司 Sunflower seed shelling method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106685A (en) * 1994-09-28 1995-08-16 孙培义 Sachet medicine
CN102349991A (en) * 2011-05-29 2012-02-15 王红芳 Composition for killing virus and preventing influenza and cold prevention plaster prepared by composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106685A (en) * 1994-09-28 1995-08-16 孙培义 Sachet medicine
CN102349991A (en) * 2011-05-29 2012-02-15 王红芳 Composition for killing virus and preventing influenza and cold prevention plaster prepared by composition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李凡成: "鼻部炎症辨证论治规律探讨", 《湖南中医药大学学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105412705A (en) * 2015-12-26 2016-03-23 卢文华 Medicine for treating acute nasosinusitis and preparation method thereof
CN112438387A (en) * 2019-09-02 2021-03-05 五原县金麦提升科技有限公司 Sunflower seed shelling method

Also Published As

Publication number Publication date
CN103638495B (en) 2015-04-08

Similar Documents

Publication Publication Date Title
CN102805805B (en) Medicament for treating rhinitis and preparation method thereof
CN104173988A (en) Medicine for treating cold and preparation method thereof
CN103656406B (en) One treats phthisical medicine and preparation method thereof
CN103520530B (en) Medicament for treating erysipelas and preparation method thereof
CN105148106A (en) Drug for treating phthisis and preparation method of drug
CN105477487A (en) Medicine for treating chronic pharyngitis and preparation method thereof
CN103638495B (en) Medicament for treating paranasal sinusitis and preparation method of medicament
CN105381411A (en) Medicine for treating epilepsy and preparation method of medicine
CN105434952A (en) Medicine for treating scarlatina and preparation method thereof
CN104398925A (en) Medicine treating dermatopathy and preparation method thereof
CN103611005B (en) Medicine for treating chronic pharyngitis and preparation method thereof
CN103656291B (en) Medicine for treating pharyngitis and preparation method thereof
CN103386066B (en) Medicine used for treating hernia and preparation method thereof
CN103656589B (en) Drug for treating viral myocarditis and preparation method thereof
CN103623297B (en) Medicine for treating acute mastitis and preparation method of medicine
CN103656294B (en) Medicine for treating acute glomerulonephritis and preparation method thereof
CN102988883B (en) Medicament for treating pneumonia and preparation method of medicament
CN103751658B (en) A kind ofly treat medicine of the hepatitis B that damp-heat accumulation causes and preparation method thereof
CN103656451B (en) Medicine for treating dampness and heat and preparation method thereof
CN103611028B (en) Medicine for treating pneumonia and preparation method thereof
CN105963586A (en) Medicine for treating lung abscess and preparation method thereof
CN105381416A (en) Medicine for treating upper gastrointestinal hemorrhage and preparation method thereof
CN105343854A (en) Medicament for treating epigastric pain and preparation method of medicament
CN103623377B (en) A kind of medicine for the treatment of arthromyodynia and preparation method thereof
CN105435034A (en) Medicine for treating hemoptysis and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150408

Termination date: 20151210

EXPY Termination of patent right or utility model