CN105521473A - Poliomyelitis sequela treatment medicine and preparation method thereof - Google Patents

Poliomyelitis sequela treatment medicine and preparation method thereof Download PDF

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CN105521473A
CN105521473A CN201511001749.9A CN201511001749A CN105521473A CN 105521473 A CN105521473 A CN 105521473A CN 201511001749 A CN201511001749 A CN 201511001749A CN 105521473 A CN105521473 A CN 105521473A
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余勇
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
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    • A61K36/11Pteridophyta or Filicophyta (ferns)
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    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
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Abstract

The invention discloses a poliomyelitis sequela treatment medicine and a preparation method thereof. The medicine is mainly prepared from Aster tataricus, Radix Ophiopogonis, Radix Astragali, Radix Codonopsis, Chinese angelica root, white peony root, Chinese magnoliavine, licorice root, Gambir Plant, honeysuckle stem and scorpion according to a certain weight ratio. The medicine has blood circulation invigorating, muscle and tendon relaxing, wind dispelling, pain relieving, toxin draining and tissue regeneration promoting, and has the advantages of fast effectiveness, good treatment effect and no side effects in alleviation and treatment of poliomyelitis sequela.

Description

A kind of medicine for the treatment of poliomyelitis sequela and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of poliomyelitis sequela and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Poliomyelitis sequela is also known as poliomyelitis sequela.It is the spinal nerves infectious disease caused by poliovirus.All can occur throughout the year, with the summer, autumn sickness rate the highest.The children's of 6 months ~ 5 years old the most easily catches an illness.Modern medicine thinks that primary disease is a kind of acute infectious intestinal disease, by poliovirus, propagate through the spittle and feces two approach, and food, water, hands and various articles for use also by virus contamination are as clothes.Toy, books etc., per os and entering, makes children's ill.Virus is main invades ventricornu motor neurocyte, is invaded position and to be inflamed pathological changes, cause respective muscle flaccid paralysis.Chinese medicine belongs to " myopathy " category primary disease.Flaccidity refers to that limbs muscle arteries and veins relaxes, and brothers wither soft unable, can not the disease of voluntary activity.Think and invade lung stomach two warp primarily of wind, cold, wet heresy, make qi and blood circulation smooth, muscles venation is lost caused by moisten and support.Or because of prolonged illness deficiency of both the liver and kidney, then see muscles and bones amyotrophy, even deformity.Because Western medicine cannot effective fast treating poliomyelitis sequela, therefore there is great demand in the Chinese medicine of people to effective treatment poliomyelitis sequela, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor, according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial, finally have found the medicine of effective remissive treatment poliomyelitis sequela, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective remissive treatment poliomyelitis sequela.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Radix Asteris selected by medicine of the present invention, Radix Ophiopogonis, the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Ramulus Uncariae Cum Uncis, Caulis Lonicerae, Scorpio, the Radix Polygoni Multiflori, Radix Achyranthis Bidentatae, Radix Puerariae, Radix Gentianae Macrophyllae, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, Concretio Silicea Bambusae, Cortex Cinnamomi, Radix Notoginseng, Caulis Akebiae, Herba Schizonepetae, Radix Saposhnikoviae, Olibanum, Myrrha, Herba speranskiae tuberculatae, Radix Peucedani, Rhizoma Polygonati, Cacumen Platycladi, Radix Clematidis, the Cortex Eucommiae, Radix Angelicae Pubescentis, Flos Carthami, Semen Persicae, Radix Dipsaci, Fructus Chaenomelis, Rhizoma Zingiberis Recens, Herba Lycopodii crude drug carries out combination preparation, each efficacy of drugs is made by these drug regimens to produce synergism, thus effectively can treat poliomyelitis sequela.Wherein, select Radix Asteris to be because its nature and flavor are bitter, temperature, enter lung meridian, have warming the lung, the therapeutic method to keep the adverse QI flowing downwards, water expectorant, the function of cough-relieving, controls wind and cold, and cough, Zhichuan, asthenia coughs vomiting bloody pus.Select be because its property sweet and slightly bitter taste Radix Ophiopogonis, cold, enter lung, stomach, heart channel, have nourishing YIN and moistening the lung, clear away heart-fire relieving restlessness, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, asthenia dysphoria with smothery sensation, and clearly yearningly, calentura Tianjin is hindered, dry mouth and throat, constipation.Select the Radix Astragali to be that tepor, enters lung, spleen channel because its nature and flavor are sweet, life defends consolidating superficial resistance with useful, inducing diuresis to remove edema, poison holding, and the function of granulation promoting, controls spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, and carbuncle is not burst or burst and holds back for a long time; Processing the function with there being invigorating middle warmer benefit, controlling internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, meridian of Foot-TAI YIN edema caused by disorder of QI, have invigorating the spleen and replenishing QI, the function of promoting the production of body fluid, controls weakness of the spleen and stomach, deficiency of both QI and blood, fatigue and lack of strength, and lack of appetite is thirsty, chronic diarrhea, proctoptosis.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm, enter the heart, liver, spleen channel, have benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize the function of laxation, control menoxenia, amenorrhea stomachache , mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood is dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty is just, heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select the Radix Paeoniae Alba to be because its nature and flavor picric acid, cool, enter liver, spleen channel, have nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, and dysentery is suffered from abdominal pain, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Fructus Schisandrae Chinensis is selected to be that temperature, enters lung, kidney channel, astringe the lung, nourishing kidney, promote the production of body fluid, and receive antiperspirant, the function of arresting seminal emission, controls the deficiency of the lung and breath with cough, and xerostomia is done thirsty, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, chronic diarrhea chronic dysentery because its nature and flavor acid.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, frightened carbuncle, raw with controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores, separates poison of drug and alimentary toxicosis.Select Ramulus Uncariae Cum Uncis to be because its nature and flavor are bitter, cool, enter liver, heart channel, have heat clearing away suppressing the hyperactive liver, the function of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., controls little Jing Epilepsy Chi Zong, adult's slight Hypertension, dizzy, dizzy, married woman's eclampsia.Caulis Lonicerae is selected to be because its nature and flavor are sweet, cold, enter the heart, lung meridian, have heat clearing away, removing toxic substances, the function of dredging collateral, control epidemic febrile disease heating, toxic-heat and blood stasis, infectious hepatitis, carbuncle sore tumefacting virus, bones and muscles pain.Select Scorpio to be because its nature and flavor are salty pungent, flat, poisonous, enter meridian of Foot-JUE YIN, dispel the wind, relieving convulsion, dredging collateral, the function of removing toxic substances, control convulsion with spasms , epilepsy, apoplexy, hemiplegia, deviation of the eye and mouth, migraine, rheumatic arthralgia, tetanus, tuberculous lymphadenitis, rubella skin ulcer swells.Radix Polygoni Multiflori is selected to be that tepor, enters liver, kidney channel, have tonifying liver, kidney tonifying, nourish blood, the function of dispeling the wind because its property bitter but sweet flavor is puckery, control hepatic and renal YIN deficiency, sending out must be early white, and blood deficiency is dizzy, and waist knee joint is weak, and muscles and bones is ached, seminal emission, metrorrhagia and leukorrhagia, chronic malaria, chronic dysentery, chronic hepatitis, carbuncle, scrofula, hemorrhoidal hamorrhage, haemorrhoids.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid, flat, enter liver, kidney channel, dissipating blood stasis blood is used in life, and the function of subduing inflammation, controls gonorrhea, hematuria, amenorrhea , mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis is suffered from abdominal pain, sore throat, carbuncle, traumatic injury, ripe invigorating the liver and kidney, bone and muscle strengthening, controls waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, have yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is quenched the thirst, cure the wound cold, warm, headache, stiffness of the nape, dysphoria with smothery sensation disappears and drinks, and has loose bowels, dysentery, and abnormal pigmentary deposit on the skin is examined not saturating, hypertension, and angina pectoris is deaf.Radix Gentianae Macrophyllae is selected to be because its nature and flavor toil, flat, enter liver, stomach, gallbladder meridian, have expelling wind and removing dampness, and blood relaxing muscles and tendons, the function of clearing away heat and promoting diuresis, dispelling the wind and dampness pathogens arthralgia pain, muscles and bones contracture, jaundice, has blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Rhizoma Et Radix Notopterygii is selected to be that temperature, enter bladder, kidney channel, have loose exterior cold, wind-damp dispelling, the function in sharp joint, cure cold wind and cold, has a headache lossless, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore because its nature and flavor are worked hard.Select Rhizoma Gastrodiae to be because its nature and flavor are sweet, flat, enter Liver Channel, have endogenous wind stopping, the function of arresting convulsion, control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia, aphasia, little Jing Epilepsy wind symptom.Select Concretio Silicea Bambusae to be that GUIXIN, Liver Channel, have clear heat and eliminate phlegm because its nature and flavor are sweet, the function of cool heart arresting convulsion, controls calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, twitches, night cry.Select Cortex Cinnamomi to be because its property acrid-sweet flavor, heat, enters kidney, spleen, urinary bladder channel, has complement sun, warming the spleen and stomach, removing accumulated cold, the function of promoting blood circulation, controls decline of the fire from the gate of life, cold extremities faint pulse, and YANG-depletion is collapsed, and stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea and mass in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, heat in the upper and cold in the lower.Select Radix Notoginseng to be because its property sweet and slightly bitter taste, temperature, enters liver, stomach, large intestine channel, has hemostasis, dissipating blood stasis, and detumescence, the function of analgesic therapy, controls haematemesis, hemoptysis, and epistaxis is had blood in stool, dysentery, metrorrhagia, mass in the abdomen, puerperal blood faints, and retention of lochia falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.Caulis Akebiae is selected to be that cool, enter the heart, small intestinal, urinary bladder channel, have pathogenic fire purging row water, the function of promoting blood circulation, controls hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis because its nature and flavor are bitter.Select Herba Schizonepetae to be that temperature, enters lung, Liver Channel, deliver, dispel the wind, the function for the treatment of blood disorders because its nature and flavor are pungent, parch to black stops blooding, and cure cold heating, headache, laryngopharynx swelling and pain, apoplexy locked mouth, and spit blood, epistaxis, has blood in stool, metrorrhagia, puerperal blood faints, carbuncle, skin ulcer scabies, scrofula.Select Radix Saposhnikoviae to be because its property acrid-sweet flavor, temperature, enters bladder, lung, spleen channel, delivers, dispel the wind, and victory is wet, and the function of pain relieving, controls affection of exogenous wind-cold, and headache is dizzy, stiffness of the nape, anemofrigid-damp arthralgia, and joint is ached, and extremity contraction is anxious, tetanus.Select Olibanum to be that temperature, enters the heart, liver, spleen channel, have regulating qi and activating blood, analgesic therapy because its nature and flavor are worked hard, chase after the function of poison, control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Myrrha is selected to be that flat, enter Liver Channel, have loose blood blood stasis removing, the function of subduing swelling and relieving pain, controls and fall damage, incised wound, muscles and bones, trusted subordinate all Tong , mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye because its nature and flavor are bitter.Select Herba speranskiae tuberculatae to be because its property and flavor of peppery and warm, dispel the wind, dehumidifying, relaxing muscles and tendons, invigorates blood circulation, the function of pain relieving, dispelling the wind and dampness pathogens arthralgia pain, muscles and bones contracture, skin ulcer tinea toxic swelling.Select Radix Peucedani to be that be slightly cold, return lung meridian, have loose wind heat clearing away, the function of lowering the adverse-rising QI to resolve phlegm, controls cough due to pathogenic wind-heat, abundant expectoration because its nature and flavor are pungent, bitter, expectorant dyspnea of heat type is full, coughs up phlegm yellow thick.Select Rhizoma Polygonati to be because its nature and flavor are sweet flat, enter spleen, lung, kidney channel, have invigorating the spleen and replenishing QI, profit cardiopulmonary, the function of bone and muscle strengthening, controls deficient cold and heat, pulmonary tuberculosis hemoptysis, after being ill the empty lack of appetite of body, and muscles and bones is weak, rheumatalgia, wind favus disease.Select Cacumen Platycladi to be because its nature and flavor are pained, cold, enter the heart, liver, large intestine channel, have removing heat from blood, hemostasis, wind-damp dispelling, the function of loose toxic swelling, controls haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, rheumatic arthralgia, bacillary dysentery, hypertension, cough, erysipelas, and mumps is scalded.Select Radix Clematidis to be because its nature and flavor are pungent salty, temperature, poisonous, enter urinary bladder channel, have wind-damp dispelling, the meridian dredging, expectorant saliva, the function of the loose hypochondriac lump, controls gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria , lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.Select the Cortex Eucommiae be because its nature and flavor sweet micro-pungent, temperature, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, antiabortive function, control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, vaginal bleeding during pregnancy for falling, hypertension.Select Radix Angelicae Pubescentis to be that temperature, enters kidney, urinary bladder channel, dispel the wind because its nature and flavor are worked hard, victory is wet, cold expelling, and the function of pain relieving, controls anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Select Flos Carthami to be that temperature, enters the heart, Liver Channel, have promoting blood circulation to restore menstrual flow, the function of blood stasis removing pain relieving, control amenorrhea , mass in the abdomen because its nature and flavor are pungent, difficult labour, stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Semen Persicae is selected to be because its property bitter but sweet flavor, flat, enter the heart, liver, large intestine channel, have blood stasis removing and clots absorbing, moisturize the function of sliding warp, control amenorrhea, mass in the abdomen, calentura blood-retention, arthralgia due to stagnation of blood, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.Select Radix Dipsaci to be that tepor, enters liver, kidney channel, have invigorating the liver and kidney, reuniting the fractured tendons and bones, and the function of blood circulation regulating, controls aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia because its nature and flavor toil, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.Fructus Chaenomelis is selected to be that temperature, enters liver, spleen channel, have suppressing the hyperactive liver and easing the stomach, the function of the relaxing muscles and tendons that dries, and controls convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery because its nature and flavor acid.Select Rhizoma Zingiberis Recens to be because its nature and flavor are pungent, temperature, enter lung, stomach, spleen channel, deliver, cold expelling, preventing or arresting vomiting, open the function of expectorant, cure cold wind and cold, vomiting, and phlegm retention, breathes with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Herba Lycopodii to be because its nature and flavor toil, temperature, enters liver, stomach, kidney three warp, has expelling wind and cold, and dehumidifying detumescence, the function of relaxing muscles and tendons to promote blood circulation, controls anemofrigid-damp arthralgia, joint aches, skin numbness, tetraparesis, edema, traumatic injury.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight:
Radix Asteris 4-8 gram, Radix Ophiopogonis 4-8 gram, Radix Astragali 10-20 gram, Radix Codonopsis 8-10 gram, Radix Angelicae Sinensis 8-10 gram, Radix Paeoniae Alba 4-5 gram, Fructus Schisandrae Chinensis 4-5 gram, Radix Glycyrrhizae 4-5 gram, Ramulus Uncariae Cum Uncis 8-10 gram, Caulis Lonicerae 8-10 gram, Scorpio 4-8 gram, Radix Polygoni Multiflori 4-8 gram, Radix Achyranthis Bidentatae 4-8 gram, Radix Puerariae 4-8 gram, Radix Gentianae Macrophyllae 4-5 gram, Rhizoma Et Radix Notopterygii 4-5 gram, Rhizoma Gastrodiae 4-5 gram, Concretio Silicea Bambusae 4-5 gram, Cortex Cinnamomi 10-20 gram, Radix Notoginseng 8-10 gram, Caulis Akebiae 8-10 gram, Herba Schizonepetae 8-10 gram, Radix Saposhnikoviae 8-10 gram, Olibanum 8-10 gram, Myrrha 8-10 gram, Herba speranskiae tuberculatae 8-10 gram, Radix Peucedani 5-7 gram, Rhizoma Polygonati 8-10 gram, Cacumen Platycladi 8-10 gram, Radix Clematidis 4-8 gram, Cortex Eucommiae 4-5 gram, Radix Angelicae Pubescentis 4-5 gram, Flos Carthami 2-3 gram, Semen Persicae 3-4 gram, Radix Dipsaci 5-6 gram, Fructus Chaenomelis 4-6 gram, Rhizoma Zingiberis Recens 4-6 gram, Herba Lycopodii 6-8 gram.
Be preferably:
Radix Asteris 6 grams, Radix Ophiopogonis 6 grams, the Radix Astragali 15 grams, Radix Codonopsis 9 grams, Radix Angelicae Sinensis 9 grams, the Radix Paeoniae Alba 4.5 grams, Fructus Schisandrae Chinensis 4.5 grams, 4.5 grams, Radix Glycyrrhizae, Ramulus Uncariae Cum Uncis 9 grams, Caulis Lonicerae 9 grams, Scorpio 6 grams, the Radix Polygoni Multiflori 6 grams, Radix Achyranthis Bidentatae 6 grams, Radix Puerariae 6 grams, Radix Gentianae Macrophyllae 4.5 grams, Rhizoma Et Radix Notopterygii 4.5 grams, 4.5 grams, Rhizoma Gastrodiae, Concretio Silicea Bambusae 4.5 grams, Cortex Cinnamomi 15 grams, Radix Notoginseng 9 grams, Caulis Akebiae 9 grams, Herba Schizonepetae 9 grams, Radix Saposhnikoviae 9 grams, Olibanum 9 grams, Myrrha 9 grams, Herba speranskiae tuberculatae 9 grams, Radix Peucedani 6 grams, Rhizoma Polygonati 9 grams, Cacumen Platycladi 9 grams, Radix Clematidis 6 grams, the Cortex Eucommiae 4.5 grams, Radix Angelicae Pubescentis 4.5 grams, 3 grams, Flos Carthami, 3 grams, Semen Persicae, Radix Dipsaci 6 grams, Fructus Chaenomelis 6 grams, 5 grams, Rhizoma Zingiberis Recens, Herba Lycopodii 7 grams.
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Radix Asteris: pick decontamination, removes residual stem, and clean, slightly moistening, is cut into segment, dries;
2, Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
3, the Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
4, Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
5, Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
6, the Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
7, Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;
8, Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, run through, section, dries;
9, Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
10, Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;
11, Scorpio: clear water floats the matter that desalts, and dries, or low baking temperature roasting is used;
12, Radix Polygoni Multiflori: pick decontamination, cleans, saturating with blister to eighty per cant, pulls out, and profit is even to inside and outside humidity, and section or dice, dry;
13, Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;
14, Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;
15, Radix Gentianae Macrophyllae: pick decontamination, except removing LU, slightly soaks, runs through section, dry;
16, Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
17, Rhizoma Gastrodiae: pick decontamination, size stepping, be soaked in water to seventy percent thoroughly, pull out, slightly dry in the air, then moisten to internal and external temperature even, section, dries;
18, Concretio Silicea Bambusae: get crude drug, removing impurity, ash bits;
19, Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
20, Radix Notoginseng: pick clean impurity, smashs to pieces and runs through rear section and dry;
21, Caulis Akebiae: slightly soak with water, moistening, to thoroughly, is cut into slices, is dried;
22, Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;
23, Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
24, Olibanum: pick the sub-impurity of shakeout;
25, Myrrha: pick decontamination, breaks into fragment;
26, Herba speranskiae tuberculatae: pick clean impurity, cutting;
27, Radix Peucedani: get crude drug, removing impurity, cleans, runs through, shave, dry, and sieve removes chip;
28, Rhizoma Polygonati: clean earth, slightly profit, section, dries;
29, Cacumen Platycladi: pick clean impurity, rubs broken destemming, well sifted ash bits;
30, Radix Clematidis: pick clean impurity, removes residual stem, is soaked in water, pull out and run through, cutting, dry;
31, the Cortex Eucommiae: removing rough bark, clean, run through, dice or strand, dry;
32, Radix Angelicae Pubescentis: pick decontamination, separately size, clean, run through rear section, dry;
33, Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
34, Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
35, Radix Dipsaci: clean silt, removing retained root head, runs through rear section and dries, sieve anti-dandruff;
36, Fructus Chaenomelis: clear water is cleaned, and slightly soaks, moistening, to thoroughly, is put in food steamer and is cooked, cut into slices while hot, weather exposure, with by red turn atropurpureus till;
37, Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
38, Herba Lycopodii: sieve dedust bits, pick clean impurity, be cut into segment;
Two, prepare
1, by the Radix Asteris of described weight, Radix Ophiopogonis, the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Ramulus Uncariae Cum Uncis, Caulis Lonicerae, Scorpio, the Radix Polygoni Multiflori, Radix Achyranthis Bidentatae, Radix Puerariae, Radix Gentianae Macrophyllae, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, Concretio Silicea Bambusae, Cortex Cinnamomi, Radix Notoginseng, Caulis Akebiae, Herba Schizonepetae, Radix Saposhnikoviae, Olibanum, Myrrha, Herba speranskiae tuberculatae, Radix Peucedani, Rhizoma Polygonati, Cacumen Platycladi, Radix Clematidis, the Cortex Eucommiae, Radix Angelicae Pubescentis, Flos Carthami, Semen Persicae, Radix Dipsaci, Fructus Chaenomelis, Rhizoma Zingiberis Recens, Herba Lycopodii puts into decocting container, add water 8 times amount for the first time, soak after 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container.
2, add water the medicinal residues of filtration 6 times amount, and intense fire boils, then within 20 minutes, filter with slow fire boiling, second time decoction liquor poured in container.
3, boiled by twice decoction liquor mixing and stirring intense fire, slow fire boiling 10 minutes, obtains medicinal liquid, is divided into 6 doses and takes.
In prescription, Rhizoma Gastrodiae has endogenous wind stopping, and the function of arresting convulsion is monarch drug; Radix Gentianae Macrophyllae expelling wind and removing dampness, and blood relaxing muscles and tendons, Radix Saposhnikoviae is delivered, and dispels the wind, victory is wet, and both pain relievings are ministerial drug, and three taste medicines play expelling wind and removing dampness, promoting blood circulation and stopping pain jointly, the effect of expelling wind for relieving convulsion, remissive treatment poliomyelitis sequela effect is comprehensive, and with endogenous wind stopping, arresting convulsion is main, can effect a permanent cure; Herba speranskiae tuberculatae dispels the wind, dehumidifying, and relaxing muscles and tendons, invigorates blood circulation, and pain relieving is adjuvant drug; Myrrha falls apart blood blood stasis removing, and subduing swelling and relieving pain is take stopgap measures with all medicines that is left.
Medicine of the present invention has relaxing muscles and tendons to promote blood circulation, wind-expelling pain-stopping, the function of promoting pus discharge and tissue regeneration strengthening, for remissive treatment poliomyelitis sequela, short treating period, instant effect, to have no side effect.
Detailed description of the invention:
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these test examples comprise animal toxicity test report and the clinical observation on the therapeutic effect data of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Taking medicinal liquid super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is administration by gavage administration, twice daily, serve on 7 days, observes administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept poliomyelitis sequela out-patient totally 28 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation is: sick just can have the diseases such as heating, headache, hyperhidrosis, general malaise, constipation or diarrhoea.Generally step back in heat, then occur that irregular, asymmetric human body is paralysed, be common in extremity, maximum with lower extremity paralysis.Most of sick child can partially or completely recover normal in 1 year, still then left paralysis sequela without recuperator after 1 year.Suffering limb muscle has atrophy in various degree, and active receiving limits, and thin, soft, cool and various deformities etc. often appear in limbs.
Diagnostic point 1, there is acute child paralysis medical history.2, age-3 years old children that are mainly in 6 months.3, degree is first heavy rear light.4, only loss of motor function, sensation and fecal and urinary functions all normal.5, paralysis is most asymmetric, and in segmental, non-clustered, quadriceps femoris is got involved at most.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, 2 times on the one, each serving with 1 dose, every day early, evening respectively takes 1 time, within 30 days, is a course for the treatment of, takes 3 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: poliomyelitis sequela transference cure, recovery from illness, body constitution recovers normal;
Take a turn for the better: poliomyelitis sequela symptom is clearly better, and amyotrophy takes a turn for the better to some extent, and body constitution is progressively recovered;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
In above-mentioned treatment, by Drug therapy poliomyelitis sequela patient 28 example of the present invention, effective 17 examples of result, obvious effective rate is 60.71%, and take a turn for the better 7 examples, and improvement rate is 25%, and invalid 4 examples, total effective rate is 85.71%.

Claims (3)

1. treat a medicine for poliomyelitis sequela, it is characterized in that: it is made up of the crude drug in following amount ranges:
Radix Asteris 4-8 gram, Radix Ophiopogonis 4-8 gram, Radix Astragali 10-20 gram, Radix Codonopsis 8-10 gram, Radix Angelicae Sinensis 8-10 gram, Radix Paeoniae Alba 4-5 gram, Fructus Schisandrae Chinensis 4-5 gram, Radix Glycyrrhizae 4-5 gram, Ramulus Uncariae Cum Uncis 8-10 gram, Caulis Lonicerae 8-10 gram, Scorpio 4-8 gram, Radix Polygoni Multiflori 4-8 gram, Radix Achyranthis Bidentatae 4-8 gram, Radix Puerariae 4-8 gram, Radix Gentianae Macrophyllae 4-5 gram, Rhizoma Et Radix Notopterygii 4-5 gram, Rhizoma Gastrodiae 4-5 gram, Concretio Silicea Bambusae 4-5 gram, Cortex Cinnamomi 10-20 gram, Radix Notoginseng 8-10 gram, Caulis Akebiae 8-10 gram, Herba Schizonepetae 8-10 gram, Radix Saposhnikoviae 8-10 gram, Olibanum 8-10 gram, Myrrha 8-10 gram, Herba speranskiae tuberculatae 8-10 gram, Radix Peucedani 5-7 gram, Radix Clematidis 4-8 gram, Cortex Eucommiae 4-5 gram, Radix Angelicae Pubescentis 4-5 gram, Flos Carthami 2-3 gram, Semen Persicae 3-4 gram, Radix Dipsaci 5-6 gram, Fructus Chaenomelis 4-6 gram, Rhizoma Zingiberis Recens 4-6 gram, Herba Lycopodii 6-8 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Asteris 6 grams, Radix Ophiopogonis 6 grams, the Radix Astragali 15 grams, Radix Codonopsis 9 grams, Radix Angelicae Sinensis 9 grams, the Radix Paeoniae Alba 4.5 grams, Fructus Schisandrae Chinensis 4.5 grams, 4.5 grams, Radix Glycyrrhizae, Ramulus Uncariae Cum Uncis 9 grams, Caulis Lonicerae 9 grams, Scorpio 6 grams, the Radix Polygoni Multiflori 6 grams, Radix Achyranthis Bidentatae 6 grams, Radix Puerariae 6 grams, Radix Gentianae Macrophyllae 4.5 grams, Rhizoma Et Radix Notopterygii 4.5 grams, 4.5 grams, Rhizoma Gastrodiae, Concretio Silicea Bambusae 4.5 grams, Cortex Cinnamomi 15 grams, Radix Notoginseng 9 grams, Caulis Akebiae 9 grams, Herba Schizonepetae 9 grams, Radix Saposhnikoviae 9 grams, Olibanum 9 grams, Myrrha 9 grams, Herba speranskiae tuberculatae 9 grams, Radix Peucedani 6 grams, Rhizoma Polygonati 9 grams, Cacumen Platycladi 9 grams, Radix Clematidis 6 grams, the Cortex Eucommiae 4.5 grams, Radix Angelicae Pubescentis 4.5 grams, 3 grams, Flos Carthami, 3 grams, Semen Persicae, Radix Dipsaci 6 grams, Fructus Chaenomelis 6 grams, 5 grams, Rhizoma Zingiberis Recens, Herba Lycopodii 7 grams.
3. the preparation method of medicine according to claim 1 or 2, it comprises the following steps:
(1) get the raw materials ready
(1) Radix Asteris: pick decontamination, removes residual stem, and clean, slightly moistening, is cut into segment, dries;
(2) Radix Ophiopogonis: pick clean impurity, be soaked in water, pull out, pump the heart after running through, then clean dry;
(3) Radix Astragali: pick clean impurity, the root head that removing is residual and hollow larger root, be soaked in water, pull out, run through rear timely section, dry;
(4) Radix Codonopsis: run through reed after cleaning silt, section or cutting, dry;
(5) Radix Angelicae Sinensis: pick decontamination, clean, moistening, slightly dries in the air, and section is dried;
(6) Radix Paeoniae Alba: pick decontamination, separately size, be soaked in water to eighty per cant thoroughly, pull out, solarization is dried in the air, and profit is even to inside and outside humidity, and section is dry;
(7) Fructus Schisandrae Chinensis: sieve dedust bits, removing impurity, put in food steamer and steam thoroughly, taking-up is dried;
(8) Radix Glycyrrhizae: pick decontamination, cleans, and when being soaked in water saturating to eighty per cant, pulling out, run through, section, dries;
(9) Ramulus Uncariae Cum Uncis: pick old stalk, impurity, cleans, dries;
(10) Caulis Lonicerae: pick decontamination, is soaked in water, and runs through, and section, dries;
(11) Scorpio: clear water floats the matter that desalts, and dries, or low baking temperature roasting is used;
(12) Radix Polygoni Multiflori: pick decontamination, cleans, saturating with blister to eighty per cant, pulls out, and profit is even to inside and outside humidity, and section or dice, dry;
(13) Radix Achyranthis Bidentatae: pick decontamination, cleans, softens, go reed, cutting, dry;
(14) Radix Puerariae: pick decontamination, cleans, is soaked in water, pulls out, run through, cut into slices in time, dry;
(15) Radix Gentianae Macrophyllae: pick decontamination, except removing LU, slightly soaks, runs through section, dry;
(16) Rhizoma Et Radix Notopterygii: pick decontamination, cleans, runs through, and section, dries;
(17) Rhizoma Gastrodiae: pick decontamination, size stepping, be soaked in water to seventy percent thoroughly, pull out, slightly dry in the air, then moisten to internal and external temperature even, section, dries;
(18) Concretio Silicea Bambusae: get crude drug, removing impurity, ash bits;
(19) Cortex Cinnamomi: pick clean impurity, scrape off rough bark, the used time smashes, or scrapes off rough bark, infiltrates a moment by warm water, and section, dries;
(20) Radix Notoginseng: pick clean impurity, smash to pieces, runs through rear section and dries;
(21) Caulis Akebiae: slightly soak with water, moistening, to thoroughly, is cut into slices, is dried;
(22) Herba Schizonepetae: pick clean impurity, with water slightly bubble, pulls cutting out, dries;
(23) Radix Saposhnikoviae: remove residual stem, be soaked in water, pull out, run through section, dry;
(24) Olibanum: pick the sub-impurity of shakeout;
(25) Myrrha: pick decontamination, breaks into fragment;
(26) Herba speranskiae tuberculatae: pick clean impurity, cutting;
(27) Radix Peucedani: get crude drug, removing impurity, cleans, runs through, shave, dry, and sieve removes chip;
(28) Rhizoma Polygonati: clean earth, slightly profit, section, dries;
(29) Cacumen Platycladi: pick clean impurity, rubs broken destemming, well sifted ash bits;
(30) Radix Clematidis: pick clean impurity, removes residual stem, is soaked in water, pull out and run through, cutting, dry;
(31) Cortex Eucommiae: removing rough bark, clean, run through, dice or strand, dry;
(32) Radix Angelicae Pubescentis: pick decontamination, separately size, clean, run through rear section, dry;
(33) Flos Carthami: pick clean impurity, removing stem and leaf, base of a fruit head, dry;
(34) Semen Persicae: removing duricrust impurity, puts in boiling water pot and boils to the micro-wrinkle of crust, pull out, immerse in cold water, rub with the hands and remove seed coat, dry, winnow with a dustpan clean;
(35) Radix Dipsaci: clean silt, removing retained root head, runs through rear section and dries, sieve anti-dandruff;
(36) Fructus Chaenomelis: clear water is cleaned, and slightly soaks, moistening, to thoroughly, is put in food steamer and is cooked, cut into slices while hot, weather exposure, with by red turn atropurpureus till;
(37) Rhizoma Zingiberis Recens: pick decontamination, cleans earth, and the used time cuts into slices;
(38) Herba Lycopodii: sieve dedust bits, pick clean impurity, be cut into segment;
(2) prepare
(1) by the Radix Asteris of described weight, Radix Ophiopogonis, the Radix Astragali, Radix Codonopsis, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Ramulus Uncariae Cum Uncis, Caulis Lonicerae, Scorpio, the Radix Polygoni Multiflori, Radix Achyranthis Bidentatae, Radix Puerariae, Radix Gentianae Macrophyllae, Rhizoma Et Radix Notopterygii, Rhizoma Gastrodiae, Concretio Silicea Bambusae, Cortex Cinnamomi, Radix Notoginseng, Caulis Akebiae, Herba Schizonepetae, Radix Saposhnikoviae, Olibanum, Myrrha, Herba speranskiae tuberculatae, Radix Peucedani, Rhizoma Polygonati, Cacumen Platycladi, Radix Clematidis, the Cortex Eucommiae, Radix Angelicae Pubescentis, Flos Carthami, Semen Persicae, Radix Dipsaci, Fructus Chaenomelis, Rhizoma Zingiberis Recens, Herba Lycopodii medicine, add water 8 times amount for the first time, soak after 60 minutes, intense fire decocts boiling, use slow fire boiling again 30 minutes, filter first time decoction liquor, first time decoction liquor is poured in container,
(2) add water the medicinal residues of filtration 6 times amount, and intense fire boils, then within 20 minutes, filter with slow fire boiling, and pour in container by second time decoction liquor, intense fire boils, then uses slow fire boiling 10 minutes;
(3) by twice decoction liquor mixing and stirring, obtain medicinal liquid, be divided into 6 doses and take.
CN201511001749.9A 2015-12-29 2015-12-29 Poliomyelitis sequela treatment medicine and preparation method thereof Withdrawn CN105521473A (en)

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CN106511820A (en) * 2016-12-29 2017-03-22 王勤 Medicine for treating polio sequelae and preparation method thereof
CN107397920A (en) * 2016-05-21 2017-11-28 陈茹 A kind of Chinese medicine composition for treating children's measles and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN107397920A (en) * 2016-05-21 2017-11-28 陈茹 A kind of Chinese medicine composition for treating children's measles and preparation method thereof
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Application publication date: 20160427